Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (nr6a1). | the number of vertebrae in pigs varies and is associated with meat productivity. wild boars, which are ancestors of domestic pigs, have 19 vertebrae. in comparison, european commercial breeds have 21-23 vertebrae, probably owing to selective breeding for enlargement of body size. we previously identified two quantitative trait loci (qtl) for the number of vertebrae on sus scrofa chromosomes (ssc) 1 and 7. these qtl explained an increase of more than two vertebrae. here, we performed a map-based ... | 2007 | 17416745 |
| an advanced sheep (ovis aries, 2n = 54) cytogenetic map and assignment of 88 new autosomal loci by fluorescence in situ hybridization and r-banding. | presented herein is an updated sheep cytogenetic map that contains 452 loci (291 type i and 161 type ii) assigned to specific chromosome bands or regions on standard r-banded ideograms. this map, which significantly extends our knowledge of the physical organization of the ovine genome, includes new assignments for 88 autosomal loci, including 74 type i loci (known genes) and 14 type ii loci (ssrs/microsatellite marker/stss), by fish-mapping and r-banding. comparison of the ovine map to the catt ... | 2007 | 17433010 |
| [laparoscopic diagnostics of the acute bowel ischemia--first experimental experience]. | aim of the study was to prove possibilities of laparoscopic diagnostics of an acute bowel ischemia when using fluorescein dye and the ultra-violet (uv) light. | 2007 | 17436677 |
| effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillation. | an impedance threshold device (itd) has been designed to enhance circulation during cpr by creating a negative intrathoracic pressure during the relaxation phase of chest compression. | 2007 | 17454804 |
| pandemic influenza planning: shouldn't swine and poultry workers be included? | recent research has demonstrated that swine and poultry professionals, especially those who work in large confinement facilities, are at markedly increased risk of zoonotic influenza virus infections. in serving as a bridging population for influenza virus spread between animals and man, these workers may introduce zoonotic influenza virus into their homes and communities as well as expose domestic swine and poultry to human influenza viruses. prolonged and intense occupational exposures of huma ... | 2007 | 17459539 |
| rational intraabdominal pressure monitoring: how to do it? | intraabdominal hypertension (iah) is increasingly appreciated by intensivists as an important cause of organ dysfunction, even at pressure levels which were previously thought to be harmless. therefore, the goal of this review is to describe the different methods commonly used in clinical practice for intraabdominal pressure (iap) measurement, the advised methodology for each measurement method, and finally to give a rational approach for iap monitoring in daily clinical practice. | 2007 | 17469698 |
| use of laryngeal mask airway compared to endotracheal tube with positive-pressure ventilation in anesthetized swine. | to compare the ease of placement and ventilatory parameters of a laryngeal mask airway (lma) with an endotracheal tube (ett) in anesthetized swine during positive-pressure ventilation (ppv). | 2007 | 17490468 |
| fibroepithelial hamartoma in a domestic pig. | this case report is the first description of a fibroepithelial hamartoma in a pig. the dysplasia, which covered half of the face of the newborn piglet, did not increase in relative size until the animal was euthanatized at 6 months of age. histologic examination revealed a moderate orthokeratotic hyperkeratosis with variable degrees of epithelial proliferation. the main body of the dysplasia consisted of collagenous fibers. in addition, some proliferating small blood vessels as well as focally g ... | 2007 | 17491090 |
| proof-of-concept study of the aer-o-scope omnidirectional colonoscopic viewing system in ex vivo and in vivo porcine models. | the limited angle of view of standard colonoscopes means that lesions can be missed. a multidirectional viewing system (omnivision) has been developed recently and has been incorporated into the aer-o-scope (gi view ltd., ramat gan, israel), a disposable, self-propelling, and self-navigating colonoscope. the objectives of this study were to qualitatively assess the sensitivity of this viewing system in an ex vivo porcine polyp induction model, and to demonstrate its feasibility and safety in liv ... | 2007 | 17516347 |
| skin changes following minor trauma. | bruises are currently evaluated by visual inspection, and little is known about the first phase after injury. the temporal development of fresh injuries must be accurately described to be able to age bruises in a reliable manner. color changes in a bruise caused by hemoglobin breakdown products will depend on the severity of the trauma, and thus on the local immune response in the skin. it is therefore important to relate the nature of the impact to the temporal tissue responses. | 2007 | 17523178 |
| transgastric cholecystectomy: transgastric accessibility to the gallbladder improved with the semf method and a novel multibending therapeutic endoscope. | transgastric cholecystectomy is thought to technically and anatomically challenge a single entry flexible endoscopic approach. | 2007 | 17531637 |
| an animal training model for endoscopic treatment of zenker's diverticulum. | zenker's diverticulum (zd) is an uncommon disease, which is typically treated surgically. the alternative to surgery is a diverticulotomy, performed endoscopically. given the rarity of this condition, it is not possible to obtain training. there has been no animal model identified that resembles the disease in human beings. | 2007 | 17531640 |
| histological and histomorphometric investigation of the condylar cartilage of juvenile pigs after anterior mandibular displacement. | the condylar cartilage of the mandible is considered a secondary growth center and represents a joint cartilage different from other cartilage structures regarding its histological structure, its histochemical and immunohistochemical properties and its growth pattern. this study aimed to histologically and histomorphometrically investigate the condylar cartilage after anterior mandibular displacement similar to functional orthopedic treatment. a total of 12 pigs (sus scrofa domesticus) aged 10 w ... | 2007 | 17534034 |
| characteristics of primary and immortalized fibroblast cells derived from the miniature and domestic pigs. | the pig, sus scrofa domestica includes both the miniature and commercial domestic breed. these animals have influenced the human life and economies and have been studied throughout history. although the miniature breeds are more recent and have increasingly been used in a variety of biomedical studies, their cell lines have rarely been established. therefore, we sought to establish primary and immortal cell lines derived from both the miniature and domestic pig to better enable insight into poss ... | 2007 | 17543094 |
| treating ischemic left ventricular dysfunction with hypertonic saline administered after coronary occlusion in pigs. | the effects of hypertonic saline on ventricular function are controversial, whether it is increasing contractility or preload. there are no data, however, on the influence of hypertonic saline in a stunned myocardium. | 2007 | 17544894 |
| the quality of chest compressions during cardiopulmonary resuscitation overrides importance of timing of defibrillation. | we address the quality of chest compressions and the impact on initial defibrillation or initial chest compressions after sudden death. | 2007 | 17550931 |
| cytochrome p450arom, androgen and estrogen receptors in pig sperm. | androgens and estrogens are crucial for mammalian sperm differentiation but their role in biology of mature male gamete is not still defined. the expression of proteins involved in the biosynthesis and action of these steroid hormones has been demonstrated in human spermatozoa, but very few data have been reported in mature sperm from non human species. the purpose of the current study was to investigate the expression of aromatase (p450arom), estrogen (eralpha/erbeta) and androgen (ar) receptor ... | 2007 | 17553131 |
| [sex-linked erythrocyte antigens of the domestic pig]. | it has been demonstrated that the domestic pig has a blood group systems whose haplotypes (complex alleles) are formed by at least three closely linked loci that are located, like the mic2 locus of human blood group systems, in the homologous region of sex chromosomes. | 2007 | 17555129 |
| effectiveness and renal tolerance of multidetector helical ct with gadobutrol: results of a comparative porcine study. | to prospectively evaluate the safety and effectiveness of high doses of 1 mol/l gadobutrol as a contrast agent for computed tomography (ct). | 2007 | 17562809 |
| the no donor sin-1 improves intestinal-arterial p(co(2)) gap in experimental endotoxemia: an animal study. | dysfunction of the microcirculation is a prominent feature of sepsis and endotoxemia. recently, it has been shown that microcirculatory alterations are completely reversed by local or systemic application of vasodilators in severely septic patients. therefore, we investigated the influence of vasodilator therapy on microcirculatory dysfunction of the ileum during endotoxic shock in a prospective, controlled animal study. | 2007 | 17567269 |
| alternative splicing and expression profile analysis of expressed sequence tags in domestic pig. | domestic pig (sus scrofa domestica) is one of the most important mammals to humans. alternative splicing is a cellular mechanism in eukaryotes that greatly increases the diversity of gene products. expression sequence tags (ests) have been widely used for gene discovery, expression profile analysis, and alternative splicing detection. in this study, a total of 712,905 ests extracted from 101 different non-normalized est libraries of the domestic pig were analyzed. these est libraries cover the n ... | 2007 | 17572361 |
| first isolation of haemophilus parasuis and other nad-dependent pasteurellaceae of swine from european wild boars. | haemophilus parasuis is a colonizer of the upper respiratory tract of pigs and the etiological agent of glässer's disease, which is characterized by a fibrinous polyserositis, meningitis and arthritis. glässer's disease has never been reported in wild boar (sus scrofa), although antibodies against h. parasuis have been detected. the goal of this study was to confirm the presence of this bacterium in wild boar by bacterial isolation and to compare the strains to h. parasuis from domesticated pigs ... | 2007 | 17574352 |
| microwave ablation with multiple simultaneously powered small-gauge triaxial antennas: results from an in vivo swine liver model. | to prospectively investigate the ability of a single generator to power multiple small-diameter antennas and create large zones of ablation in an in vivo swine liver model. | 2007 | 17581900 |
| identification of genotype 4 hepatitis e virus strains from a patient with acute hepatitis e and farm pigs in bali, indonesia. | a previous study revealed that antibodies to hepatitis e virus (hev) (anti-hev) are highly prevalent among healthy individuals and farm pigs in bali, indonesia, and suggested that hev infection may occur via zoonosis among balinese people. however, there were no reports of acute hepatitis e in bali. to elucidate whether balinese hev strains recovered from infected humans and pigs have significant sequence similarity, serum samples obtained from 57 patients (age, mean +/- standard deviation, 31.1 ... | 2007 | 17596841 |
| positive effect of darbepoetin on peri-infarction remodeling in a porcine model of myocardial ischemia-reperfusion. | erythropoietin (epo) has anti-apoptotic and pro-angiogenic effects in rodent models of myocardial infarction (mi). we tested the hypothesis that a long-acting epo derivative (darbepoetin) has a beneficial effect on infarct size and peri-infarct remodeling in a clinically relevant large animal model of ischemia-reperfusion. a human acute mi scenario was simulated in 16 domestic pigs by inflating an angioplasty balloon in the proximal left circumflex (lcx) artery for 60 min. the animals were rando ... | 2007 | 17597149 |
| analysis of the full-length genome of hepatitis e virus isolates obtained from farm pigs in mongolia. | although no outbreaks of hepatitis e have been reported in mongolia, a significant proportion of the general population had antibodies to hepatitis e virus (hev). to investigate whether pigs are possible reservoirs of hev in mongolia, serum samples obtained from 243 2- or 3-month-old pigs on four swine farms surrounding ulaanbaatar, the capital city of mongolia, were tested for the presence of anti-hev antibodies and hev rna. overall, 223 pigs (91.8%) tested positive for anti-hev, while 89 pigs ... | 2007 | 17597486 |
| laboratory and clinical development of single keyhole umbilical nephrectomy. | to describe our initial experience with single keyhole nephrectomy in a porcine model and in human subjects. | 2007 | 18158008 |
| a porcine deep vein thrombosis model for magnetic resonance-guided monitoring of different thrombectomy procedures. | to establish a porcine model of deep iliac vein thrombosis, which allows monitoring of thrombectomy and thrombolytic procedures by magnetic resonance imaging (mri). | 2007 | 18030194 |
| assessment of global left and right ventricular function using dual-source computed tomography (dsct) in comparison to mri: an experimental study in a porcine model. | we sought to evaluate the ability of retrospectively ecg-gated dual-source computed tomography (dsct) to assess left (lv) and right ventricular (rv) functional parameters in comparison to 1.5 t magnetic resonance imaging (mri). | 2007 | 18030198 |
| the sarcocystis-cyst containing beef and pork as the sources of natural intestinal sarcocystosis in thai people. | human intestinal sarcocystosis is a zoonotic disease caused by two coccidians, i.e. sarcocystis fusiformis (syn. s. bovihominis, s. hominis) due to consumption of raw infected beef and sarcocystis meischeriana (syn. s. suihominis) due to consumption of infected raw pork. in 1987, survey of the macroscopic s. fusiformis cysts in market beef mainly from old water buffalos aged more than 15 years were commonly observed in bangkok. in 2005, the macroscopic cyst was no longer seen in beef of cattle a ... | 2007 | 18041433 |
| interstitial laser ablation of the kidney: acute and chronic porcine study using new-generation diffuser tip fiber. | many ablative techniques have been described for treatment of small renal tumors. we investigated interstitial laser ablation (ila) of porcine kidneys with a new-generation diffuser tip fiber. | 2007 | 18042035 |
| value of skin punch biopsies for the diagnosis of acute classical swine fever. | the objective of this study was to determine if skin punch biopsies are appropriate for the diagnosis of classical swine fever. for this purpose, 6 wild boars and 2 domestic pigs were experimentally infected with the highly virulent classical swine fever virus (csfv) koslov and 5 domestic pigs with a csfv field isolate (genotype 2.3 uelzen) derived from wild boar. skin biopsy specimens were tested using virus isolation, real-time reverse transcription polymerase chain reaction (rtrt-pcr), and fl ... | 2007 | 17998561 |
| survival of trichinella papuae muscle larvae in a pig carcass maintained under simulated natural conditions in papua new guinea. | in papua new guinea, trichinella papuae, a non-encapsulated species, is circulating among wild and domestic pigs and saltwater crocodiles. since an important phase of the life cycle of nematodes of the genus trichinella is the time of survival of infective larvae in decaying muscle tissues of the hosts, the carcass of a pig, experimentally infected with larvae of t. papuae, was exposed to the environmental conditions of papua new guinea to establish how long these larvae would survive and remain ... | 2007 | 18005466 |
| population phylogenomic analysis of mitochondrial dna in wild boars and domestic pigs revealed multiple domestication events in east asia. | previously reported evidence indicates that pigs were independently domesticated in multiple places throughout the world. however, a detailed picture of the origin and dispersal of domestic pigs in east asia has not yet been reported. | 2007 | 18021448 |
| [transmission of agents of the porcine respiratory disease complex (prdc) between swine herds: a review. part 2--pathogen transmission via semen, air and living/nonliving vectors]. | the transmission of prdc-pathogens (prrsv, influenza virus a, pcv2, m. hyopneumoniae, a. pleuropneumoniae) between swine herds, which was summarized in the first part of the review, mainly occurs via pig movement. the risk of pathogen transmission by insemination with contaminated semen plays only a relevant role in the infection with prrsv and pcv2. a risk of the aerogen transmission of pathogens between herds within a distance of 2 to 3 km is described for m. hyopneumoniae and prrsv. evidence ... | 2007 | 17970334 |
| composition of intestinal enterobacteriaceae populations of healthy domestic pigs. | in this study, the enterobacteriaceae microbiota, including their diversity as well as the distribution of haemolytic and virulence gene-harbouring escherichia coli of 56-day-old healthy piglets, was characterized. both the composition and the diversity of enterobacteriaceae populations varied considerably between individual pigs and intestinal sections. e. coli, enterobacter cloacae, citrobacter freundii and klebsiella pneumoniae dominated the enterobacteriaceae microbiota. however, mucosa-asso ... | 2007 | 17975092 |
| fibrinolytic treatment improves the quality of lungs retrieved from non-heart-beating donors. | the use of non-heart-beating donors (nhbds) is an alternative strategy to increase the limited number of donors. the ex vivo evaluation has been proposed to assess the function of the lungs from nhbds as an interim evaluation of the graft before transplantation. we evaluated the effect of a fibrinolytic agent, urokinase, in a pig ex vivo evaluation model. | 2007 | 17919627 |
| angiographic, ultrasonographic, and macroscopic assessment of aortic growth after vcs clips, interrupted polypropylene, or running polyglycolic acid anastomosis. | lack of growth after surgery is still an unsolved issue in growing vessels. aortic surgery is an integral part of vascular pediatric surgery. as an alternative to address this lack of growth in this scenario, we propose the use of titanium clips for vascular anastomosis. | 2007 | 17923198 |
| inhibition of pseudointimal hyperplasia in swine tips models: the efficacy of local delivery of paclitaxel using a perforated balloon catheter. | the aim of this study was to investigate the efficacy and feasibility of local delivery of paclitaxel to inhibit pseudointimal hyperplasia/intimal hyperplasia in swine transjugular intrahepatic portosystemic shunt (tips) models tips were created in seven healthy domestic swine (15-20 kg). before tips stent insertion, we performed a short-term infusion of paclitaxel (treatment group: n = 4) and saline (control group: n = 3) into the tips tract using a balloon catheter in which two 0.010 inch hole ... | 2007 | 17928498 |
| immunity against ns3 protein of classical swine fever virus does not protect against lethal challenge infection. | classical swine fever is a highly contagious disease of swine caused by classical swine fever virus, an oie list a pathogen. in the european union the virus has been eradicated from the domestic pig population and prophylactic immunization has been banned. nevertheless, intervention immunizations using marker vaccines are one possibility to deal with reintroduced csfv. at present, baculovirus-expressed e2 protein is used as such a marker vaccine. however, this vaccine cannot fully protect agains ... | 2007 | 17931119 |
| the wild boar (sus scrofa) lymphocyte function-associated antigen-1 (cd11a/cd18) receptor: cdna sequencing, structure analysis and comparison with homologues. | the most predominant beta2-integrin lymphocyte function-associated antigen-1 (lfa-1, cd11a/cd18, alphalbeta2), expressed on all leukocytes, is essential for many adhesive functions of the immune system. interestingly, rtx toxin-producing bacteria specifically target this leukocyte beta2-integrin which exacerbates lesions and disease development. | 2007 | 17937788 |
| less smoke and minimal tissue carbonization using a thulium laser for laparoscopic partial nephrectomy without hilar clamping in a porcine model. | we evaluated the utility of a thulium laser and a novel implementation of its use for laparoscopic partial nephrectomy to achieve precise, smokeless, and hemostatic dissection without hilar clamping and with minimal charring in a porcine model. | 2007 | 17941795 |
| use of concentrated human albumin with argon-beam coagulation in laparoscopic partial nephrectomy. | laparoscopic partial nephrectomy (lpn) remains a technically challenging procedure mainly because of the lack of reliable methods of hemostasis. we evaluated the feasibility of using concentrated human albumin with argon-beam coagulation to control hemorrhaging and urinary leakage during lpn. | 2007 | 17941797 |
| zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism. | to investigate whether sodium-hydrogen exchanger isoform-1 (nhe-1) inhibition attenuates myocardial injury during resuscitation from ventricular fibrillation through effects on energy metabolism, using an open-chest pig model in which coronary perfusion was controlled by extracorporeal circulation. | 2007 | 17944021 |
| [early sibling aggression in mammals and its hormonal correlates]. | early sibling aggression is a widespread phenomenon in birds. ornithologists distinguish species with "obligate" and "facultative" siblicide. sibling aggression was described in some mammal species: the domestic pig (sus scrofa), the spotted hyena (crocuta crocuta), the eurasian lynx (lynx lynx), and the iberian lynx (l. par-dinus). in all of them, sibling aggression corresponds well with the "facultative" siblicide model in birds. sibling aggression was observed at the age of 36-64 days in both ... | 2007 | 17944114 |
| molecular coronary mr imaging of human thrombi using ep-2104r, a fibrin-targeted contrast agent: experimental study in a swine model. | the aim of this study was to investigate the use of a fibrin-specific contrast agent (ep-2104r, epix pharmaceuticals, lexington, massachusetts, usa) for targeted molecular magnetic resonance (mr) imaging of human clot material removed from patients in a model of coronary thrombosis in swine. | 2007 | 17948194 |
| chromosomal instability in afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies. | extant placental mammals are divided into four major clades (laurasiatheria, supraprimates, xenarthra and afrotheria). given that afrotheria is generally thought to root the eutherian tree in phylogenetic analysis of large nuclear gene data sets, the study of the organization of the genomes of afrotherian species provides new insights into the dynamics of mammalian chromosomal evolution. here we test if there are chromosomal bands with a high tendency to break and reorganize in afrotheria, and b ... | 2007 | 17958882 |
| the epidemiology of animal trichinellosis in china. | the epidemiology of animal trichinellosis in china based mainly upon original chinese literature published between 1937 and 2004 is reviewed. the seroprevalence of trichinella infection in herbivores was 0.7% (2/300) in cattle and 0.8% (4/500) in sheep. the prevalence of trichinellosis in naturally infected cattle was 1.2% (2/163). trichinella larvae were detected in 1.4% (3/215) of sheep and in 2.1% (1/47) of beef cattle sold at markets. canine trichinellosis was recorded in 13 provinces, auton ... | 2007 | 16162414 |
| implantation and testing of subretinal film electrodes in domestic pigs. | by definition, an electronic subretinal visual prosthesis requires the implantation of stimulation electrodes in the subretinal space of the eye. polyimide film electrodes with flat contacts were implanted subretinally and used for electrical stimulation in acute experiments in anaesthetised domestic pigs. in two pigs, the film electrode was inserted through a sclerostomy into the vitreous cavity and, subsequently, via a retinotomy into the subretinal space around the posterior pole (ab interno ... | 2006 | 16125172 |
| antioxidant enzymes in ringed seal tissues: potential protection against dive-associated ischemia/reperfusion. | diving seals experience heart rate reduction and preferential distribution of the oxygenated blood flow to the heart and brain, widespread peripheral vasoconstriction, and selective ischemia in the most hypoxia-tolerant tissues. the first breath after the dive restores the oxygenated blood flow to all tissues and raises the potential for the production of reactive oxygen species (ros). we hypothesized that in order to counteract the damaging effects of ros and to tolerate repetitive cycles of is ... | 2006 | 16269268 |
| acute inhibition of the endogenous xanthine oxidase improves renal hemodynamics in hypercholesterolemic pigs. | hypercholesterolemia (hc), a major risk factor for onset and progression of renal disease, is associated with increased oxidative stress, potentially causing endothelial dysfunction. one of the sources of superoxide anion is xanthine oxidase (xo), but its contribution to renal endothelial function in hc remains unclear. we tested the hypothesis that xo modulates renal hemodynamics and endothelial function in hc pigs. four groups (n = 23) of female domestic pigs were studied 12 wk after either no ... | 2006 | 16284087 |
| prp modulates expression of bone matrix proteins in vivo without long-term effects on bone formation. | this experimental study (domestic pig) examined the bone formation after filling defined defects of the frontal skull with autogenous bone or a deproteinized bovine bone matrix (dbbm) in combination with platelet-rich plasma (prp). six groups, both materials with and without prp in two different concentrations (4.1x and 6.5x referring to untreated whole blood) were evaluated at 2, 4, 12, and 26 weeks by means of immunohistochemical staining for different bone matrix proteins, microradiography, l ... | 2006 | 16257592 |
| enhanced external counterpulsation improves endothelium-dependent vasorelaxation in the carotid arteries of hypercholesterolemic pigs. | enhanced external counterpulsation (eecp) has been demonstrated to be an effective method for the treatment of atherosclerotic vascular disease. however, the exact mechanism underlying the beneficial effects of eecp is not completely clear. we hypothesized that eecp leads to improvement in endothelial function, contributing to its clinical benefits. | 2006 | 16310261 |
| genetic characterization of type 2 porcine circoviruses detected in hungarian wild boars. | porcine circoviruses (pcv) are present in pigs worldwide; they are grouped into two types: pcv1 comprising non-pathogenic viruses and pcv2 responsible for several clinical manifestations. both types are frequently detected in domestic pigs, the prevalence and role of pcv in wild boars however, is not well studied. during the years 2002-2003 over 2000 organ samples of hungarian wild boars were collected, grouped and samples from 307 different animals were tested by polymerase chain reaction for t ... | 2006 | 16328152 |
| people, pigs and parasites in new guinea: relational contexts and epidemiological possibilities. | within papua new guinea the relationship people have with their pigs varies between societies. these differences arise in the earliest phase of rearing piglets and result in domestic animals whose primary attachments are to other pigs, to places or to people. for papua new guineans, different pig management regimes fulfill ecological and social needs. in addition, however, the ways in which pigs are raised and managed, and the presence or absence of a local population of wild pigs, have conseque ... | 2006 | 16337181 |
| molecular cloning, expression and functional characterization of miniature swine cd86. | cd86 is one of the key molecules involved in the co-stimulation of t cells. the complete cdna encoding cd86 molecule of miniature swine was cloned and analyzed. a comparison of two cd86 amino acid sequences of miniature swine and domestic swine showed only three amino acid differences suggesting that it is unlikely to affect the major structural features of the miniature swine cd86 (mscd86). in the expression study, constitutive expression of cd86 mrna was detected in various tissues, and the ab ... | 2006 | 16337491 |
| the ppar-alpha activator fenofibrate fails to provide myocardial protection in ischemia and reperfusion in pigs. | rodent studies suggest that peroxisome proliferator-activated receptor-alpha (ppar-alpha) activation reduces myocardial ischemia-reperfusion (i/r) injury and infarct size; however, effects of ppar-alpha activation in large animal models of myocardial i/r are unknown. we determined whether chronic treatment with the ppar-alpha activator fenofibrate affects myocardial i/r injury in pigs. domestic farm pigs were assigned to treatment with fenofibrate 50 mg.kg(-1).day(-1) orally or no drug treatment ... | 2006 | 16339839 |
| a new method of selective, rapid cooling of the brain: an experimental study. | to determine whether retrograde perfusion of cooled blood into one internal jugular vein (ijv) in the pig can selectively reduce the brain temperature without affecting the core body temperature (cbt). | 2006 | 16362468 |
| healing pattern of bone defects covered by different membrane types--a histologic study in the porcine mandible. | few investigations on guided bone regeneration (gbr) focus on the behaviour of tissues adjacent to barrier membranes. this study was conducted to (1) evaluate the barrier function potential of different resorbable and nonresorbable membranes for gbr, (2) investigate their structural changes after different intervals, and (3) characterize tissue composition and reaction adjacent to the barrier by qualitative histologic evaluation. seven barriers for gbr were used per animal (made of dense or expa ... | 2006 | 16362958 |
| [wild and domestic animals as permanent trichinella reservoir in poland]. | [corrected] since owen first described trichinella as a human patogen in 1835, the number of organisms comprising this genus has grown dramatically. this etiological agent of human trichinellosis shows worldwide distribution in domestic and/or sylvatic animals. | 2006 | 17432240 |
| biomechanical response of the pediatric abdomen, part 1: development of an experimental model and quantification of structural response to dynamic belt loading. | the abdomen is the second most commonly injured region in children using adult seat belts, but engineers are limited in their efforts to design systems that mitigate these injuries since no current pediatric dummy has the capability to quantify injury risk from loading to the abdomen. this paper develops a porcine (sus scrofa domestica) model of the 6-year-old human's abdomen, and then defines the biomechanical response of this abdominal model. first, a detailed abdominal necropsy study was unde ... | 2006 | 17311157 |
| seasonality of reproduction in gilts and sows. | in the wild, the pig adapts her reproductive functions according to the seasonal changes in the environment, such as the ambient temperature and availability of food. like in other short day seasonal breeders, breeding season is favoured in the mid winter in order to provide the offspring with the best chances to survive four months later. seasonal changes in environment are perceived mainly by the ability of the pig to recognise seasonal changes in photoperiod. this information is mediated thro ... | 2006 | 16866319 |
| testis morphometry, duration of spermatogenesis, and spermatogenic efficiency in the wild boar (sus scrofa scrofa). | the wild boar is a natural inhabitant of europe, asia, and north africa and is phylogenetically the ancestor of the domestic pig. because of its phylogenetic and economic importance, this species is an interesting model for studying testis function in boars. therefore, the present study was performed to investigate the testis structure, spermatogenic cycle length, and sertoli cell (sc) and spermatogenic efficiencies in eight adult wild boars. each spermatogenic cycle lasted 9.05 days, and the to ... | 2006 | 16870941 |
| retinal oximetry using intravitreal illumination. | to demonstrate spectroscopic retinal oximetry measurements on arteries and veins in swine using intravitreal illumination. retinal arterial and venous saturations are measured for a range of inspired o2 levels after pars plana vitrectomy. | 2006 | 16877270 |
| optic nerve ph and po2: the effects of carbonic anhydrase inhibition, and metabolic and respiratory acidosis. | earlier studies have demonstrated that carbonic anhydrase inhibitors (cais) increase optic nerve oxygen tension (onpo(2)) in pigs. we hypothesized that the mechanism of this effect was either a co(2) increase or a ph decrease in tissue and blood. to test this hypothesis we investigated and compared how optic nerve ph (onph) and onpo(2) are affected by: (1) carbonic anhydrase inhibition; (2) respiratory acidosis, and (3) metabolic acidosis. we measured onph with a glass ph electrode and onpo(2) w ... | 2006 | 16879567 |
| adaptive conditioning of skeletal muscle in a large animal model (sus domesticus). | recognition of the adaptive capacity of mammalian skeletal muscle has opened the way to a number of clinical applications. for most of these, the fast, fatigue-susceptible fibres need to be transformed stably to fast, fatigue-resistant fibres that express the 2a myosin heavy chain isoform. the thresholds for activity-induced change are size-dependent, so although the requisite patterns of electrical stimulation are known for the rabbit, in humans these same patterns would produce type 1 fibre ch ... | 2006 | 16879597 |
| auto-transplantation of the uterus in the domestic pig (sus scrofa): surgical technique and early reperfusion events. | to develop a method for auto-transplantation of the uterus in the pig and to evaluate the early reperfusion events after short-term cold ischemia. | 2006 | 16882260 |
| [diversity of wild and domestic pig populations estimated by a set of serum allotypes]. | variation of serum protein allotypes serving as genetic markers of the blood has been analyzed in 29 populations of the domestic pig and subspecies of the wild boar. the population biodiversity and genetic structure have been estimated by two methods: by the frequencies of allotype combinations and with the use of a map constructed in the space of two principal components. the results obtained are the basis for determining the characteristics of the microevolution of wild boars and formation of ... | 2006 | 16649668 |
| the peritoneal cavity is a distinct compartment of angiogenic molecular mediators. | this study was designed to analyze porcine plasma and peritoneal fluid for concentration differences of angiogenic molecular mediators and to determine local peritoneal sites of production of these molecules. | 2006 | 16650862 |
| tensile strength comparison of small intestinal submucosa body wall repair. | porcine small intestinal submucosa (sis) has been studied for body wall repair. however, the best method to implant the biological material has not been investigated. the objective of this study was to compare tensile strengths achieved after healing when sis was placed using three implant techniques (onlay, inlay, underlay) in a porcine model of abdominal wall defect. | 2006 | 16650864 |
| intracoronary aqueous oxygen perfusion, performed 24 h after the onset of postinfarction reperfusion, experimentally reduces infarct size and improves left ventricular function. | intracoronary aqueous oxygen (ao) hyperoxemic perfusion, initiated shortly (15-30 min) after the onset of postinfarction reperfusion, reduces infarct size and improves left ventricular function. whether such therapy provides similar benefits when administered many hours after the onset of reperfusion is unknown. accordingly, the hypothesis was tested that ao hyperbaric perfusion, performed 24 h after the onset of postinfarction reperfusion, reduces infarct size and improves left ventricular ejec ... | 2006 | 16650907 |
| the safety of autologous intracoronary stem cell injections in a porcine model of chronic myocardial ischemia. | intracoronary mononuclear cell therapy may produce angiogenesis in chronic myocardial ischemia. potential complications include periprocedural infarction secondary to: reduced coronary blood flow; hyperviscosity from the cell preparation; or microvascular dysfunction. to date, no studies to evaluate these potential complications have been reported. the objective of this report was to study the safety and feasibility of intracoronary injections of autologous bone marrow mononuclear cells in a por ... | 2006 | 16670448 |
| infection of pigs in ireland with lymphotropic gamma-herpesviruses and relationship to postweaning multisystemic wasting syndrome. | three species of porcine lymphotropic herpesviruses (plhvs) have been described but there are few reports on the distribution and prevalence of these viruses in domestic pigs. we aimed to determine the plhv status of irish commercial pig herds, and to this end spleens taken from 110 healthy adult pigs sourced from 22 geographically distributed farms in ireland were analysed for plhv dna using novel species-specific polymerase chain reaction assays. we now report that plhv infection is widespread ... | 2006 | 16672182 |
| differences in femoral compact bone tissue microscopic structure between adult cows (bos taurus) and pigs (sus scrofa domestica). | the purpose of this investigation was to study in detail compact bone tissue microscopic structure of adult cows and pigs with an emphasis to find an adequate key for the species identification. altogether 18 femurs were analysed. each of the bones was sectioned at the smallest breadth of their diaphysis. specimens were prepared using standard histological equipment, producing thin sections approximately 80-100 mum thick. the qualitative differences between investigated species were examined in ... | 2006 | 16677211 |
| hydroxyethyl starch 130 kd/0.4 and albumin improve cvvh biocompatibility whereas gelatin and hydroxyethyl starch 200 kd/0.5 lead to adverse side effects of cvvh in anesthetized pigs. | both fluid management and renal replacement therapies play a fundamental role in the treatment of critically ill patients. in a recent in vitro study, we have shown specific interactions of different colloids and the hemocompatibility of hemofilters. the present study was performed to compare the five most common fluids for volume resuscitation, i.e., normal saline (sal), hydroxyethyl starch 130 kd/0.4 (hes130), hydroxyethyl starch 200 kd/0.5 (hes200), albumin (alb), and gelatin (gel) with respe ... | 2006 | 16680020 |
| preclinical safety assessment of a dna vaccine using particle-mediated epidermal delivery in domestic pig, minipig and mouse. | dna vaccination involves the direct injection of genes coding for specific antigenic proteins. one technique known as particle-mediated epidermal delivery (pmed) is a practical approach for epidermal delivery and provides a strong immune response. an important aspect of the preclinical safety assessment of dna vaccines is the selection of a pharmacologically relevant animal model for the assessment of antigen expression, optimization of delivery and formulation of the plasmid. this paper describ ... | 2006 | 16713213 |
| [genetic typing of classical swine fever viruses--a review]. | classical swine fever (csf) is a notifiable disease of domestic pigs and wild boar. it is caused by the highly contagious csf virus and in its acute form the disease generally results in high morbidity and mortality. due to the great economical impact an outbreak can cause to the pig industry it is one of the most important swine diseases worldwide. to limit the damage in the case of a new outbreak it is necessary to identify the virus as fast as possible. this information helps epidemiologists ... | 2006 | 16716047 |
| replication of classical swine fever virus strains and isolates in different porcine cell lines. | classical swine fever virus (csfv) is an economically important pathogen of domestic pigs and wild boar. due to the highly variable clinical picture of csf, laboratory methods are essential for an unambiguous diagnosis. virus isolation using cell culture is still considered the gold standard. it is based on the incubation of permissive cells with organ or leukocyte preparations followed by antigen detection. in the "eu diagnostic manual for csf diagnosis", the permanent cell line pk(15) (porcine ... | 2006 | 16716048 |
| case report: the significance of genotyping for the epidemiological tracing of classical swine fever (csf). | in germany, eleven outbreaks of csf in domestic pig holdings were reported in 2002. they occurred exclusively in regions where csf virus circulated in the wild boar population. in ten cases the phylogenetic analysis revealed that the isolates from domestic pigs and wild boar had identical sequences in the 5' non-translated region (5'ntr). however, in one case a subtype was isolated which was slightly different from the virus subtype found in the wild boar population of that region. this case is ... | 2006 | 16716053 |
| the minipig in toxicology. | the use of pigs (sus scrofa) in biomedical research is well established in particular in surgical and physiological research. for years both pigs and minipigs have been used in pharmacology and toxicology to answer specific questions when the more conventional species have been found unsuitable. the development of minipigs has resulted in strains of more manageable size than the domestic pig. because of their well-accepted physiological and other similarities to humans, minipigs are becoming inc ... | 2006 | 16725317 |
| domestic swine in a visceral leishmaniasis endemic area produce antibodies against multiple leishmania infantum antigens but apparently resist to l. infantum infection. | in order to investigate whether pigs can be infected by leishmania infantum, a serological and parasitological study was carried out on swine in the jequié municipality, northeast of brazil. anti-leishmania infantum antibodies were detected in 37 out of 92 swine (40.2%), by two different assays: an anti-l. infantum lysate and an anti-k39 recombinant protein elisa. an experimental study was also carried out to verify the susceptibility of domestic pigs to l. infantum infection. three sows inocula ... | 2006 | 16730628 |
| monitoring of classical swine fever in wild boar (sus scrofa) in slovenia. | classical swine fever (csf) is a highly contagious multi-systemic haemorrhagic viral disease of pigs. not only domestic pigs, but also wild boar appear to play a crucial role in the epidemiology of csf. spleen (n = 739) and blood coagulum (n = 562) sampled from wild boars (sus scrofa) shot in 2002, and serum samples from 746 wild boar shot in 2003 and 2004, were tested throughout slovenia. in 2002, 17 samples were positive on enzyme-linked immunosorbent assay (elisa) test for antibodies against ... | 2006 | 16732885 |
| measuring the extent of linkage disequilibrium in commercial pig populations. | to evaluate the extent of linkage disequilibrium in domestic pigs, we genotyped 33 and 44 unrelated individuals from two commercial populations for 29 and five microsatellite markers located on chromosomes 15 and 2 respectively. a high proportion of marker pairs up to 40 cm apart exhibited significant linkage disequilibrium in both populations. pair-wise r(2) values averaged between 0.15 and 0.50 (depending on chromosome and population) for markers <1 cm apart and declined to values of 0.05 for ... | 2006 | 16734681 |
| identification of a single killer immunoglobulin-like receptor (kir) gene in the porcine leukocyte receptor complex on chromosome 6q. | human killer immunoglobulin-like receptors (kir) are expressed on natural killer (nk) cells and are involved in their immunoreactivity. while kir with a long cytoplasmic tail deliver an inhibitory signal when bound to their respective major histocompatibility complex class i ligands, kir with a short cytoplasmic tail can activate nk responses. the expansion of the kir gene family originally appeared to be a phenomenon restricted to primates (human, apes, and monkeys) in comparison to rodents, wh ... | 2006 | 16738944 |
| some factors affecting skin and wound healing. | the domestic pig is the preferred animal for studying the effects of environmental factors on skin and wound because its integument is more like that of man than any other. the three factors that most drastically affect the pattern, speed and quality of healing are dehydration of exposed tissues, the status of the blood supply bringing oxygen and nutrients to the area and sepsis. wounds exposed to the air lose water vapour, the upper dermis dries and healing takes place beneath a dry scab. cover ... | 2006 | 16752710 |
| one-shock versus three-shock defibrillation protocol significantly improves outcome in a porcine model of prolonged ventricular fibrillation cardiac arrest. | the success of resuscitation with a 1-shock versus the conventional 3-shock defibrillation protocol was investigated subject to the range of treatment variation imposed by automated external defibrillators (aeds). | 2006 | 16754801 |
| histological and fluorescence microscopic examination of the bone/implant interface in orthodontic miniscrews (mondeal). | the temporary nature of orthodontic implants demands optimisation of size and design in order to minimise damage and risk to the patient. slender and shorter miniscrews offer the advantage over conventional implants of easier and more ubiquitous positioning with minimised risk of injury to neighbouring anatomical structures such as tooth roots, nerves or vessels. the question is raised, however, as to what extent these advantages are gained at the price of diminished stability or a more unfavour ... | 2006 | 16783742 |
| mitochondrial diversity in european and chinese pigs is consistent with population expansions that occurred prior to domestication. | mitochondrial dna (mtdna) diversity in european and asian pigs was assessed using 1536 samples representing 45 european and 21 chinese breeds. diagnostic nucleotide differences in the cytochrome b (cytb) gene between the european and asian mtdna variants were determined by pyrosequencing as a rapid screening method. subsequently, 637bp of the hypervariable control region was sequenced to further characterize mtdna diversity. all sequences belonged to the d1 and d2 clusters of pig mtdna originati ... | 2006 | 16790414 |
| influence of negative expiratory pressure ventilation on hemodynamic variables during severe hemorrhagic shock. | outcome after trauma with severe hemorrhagic shock is still dismal. since the majority of blood is present in the venous vessels, it might be beneficial to perform venous recruiting via the airway during severe hemorrhagic shock. therefore, the purpose of our study was to evaluate the effects of negative expiratory pressure ventilation on mean arterial blood pressure, cardiac output, and short-term survival during severe hemorrhagic shock. | 2006 | 16791108 |
| in planta production of two peptides of the classical swine fever virus (csfv) e2 glycoprotein fused to the coat protein of potato virus x. | classical swine fever (csfv) is one of the most important viral infectious diseases affecting wild boars and domestic pigs. the etiological agent of the disease is the csf virus, a single stranded rna virus belonging to the family flaviviridae. all preventive measures in domestic pigs have been focused in interrupting the chain of infection and in avoiding the spread of csfv within wild boars as well as interrupting transmission from wild boars to domestic pigs. the use of plant based vaccine ag ... | 2006 | 16792815 |
| evaluation of myocardial metabolism with microdialysis after protection with cold blood- or cold crystalloid cardioplegia. a porcine model. | there has been a considerable change in the patient population referred for cardiac surgery in the last decade. more complex and marginal patients require optimized myocardial protection. an insufficient cardioplegic procedure results in anaerobic metabolism during cardiac arrest with subsequent lactate accumulation. increased lactate level is regarded as a predictor for low cardiac output syndrome. in an acute porcine model we examined two standard cardioplegic methods. myocardial microdialysis ... | 2006 | 16798667 |
| multislice computed tomography and magnetic resonance imaging for the assessment of reperfused acute myocardial infarction. | we evaluated the accuracy of in vivo delayed-enhancement multislice computed tomography (de-msct) and delayed-enhancement magnetic resonance imaging (de-mri) for the assessment of myocardial infarct size using postmortem triphenyltetrazolium chloride (ttc) pathology as standard of reference. | 2006 | 16814660 |
| luteinization of porcine preovulatory follicles leads to systematic changes in follicular gene expression. | the lh surge initiates the luteinization of preovulatory follicles and causes hormonal and structural changes that ultimately lead to ovulation and the formation of corpora lutea. the objective of the study was to examine gene expression in ovarian follicles (n = 11) collected from pigs (sus scrofa domestica) approaching estrus (estrogenic preovulatory follicle; n = 6 follicles from two sows) and in ovarian follicles collected from pigs on the second day of estrus (preovulatory follicles that we ... | 2006 | 16816339 |
| reconstructing impairment of secretory ameloblast function in porcine teeth by analysis of morphological alterations in dental enamel. | we studied the relationship between the macroscopic appearance of hypoplastic defects in the dental enamel of wild boar and domestic pigs, and microstructural enamel changes, at both the light and the scanning electron microscopic levels. deviations from normal enamel microstructure were used to reconstruct the functional and related morphological changes of the secretory ameloblasts caused by the action of stress factors during amelogenesis. the deduced reaction pattern of the secretory amelobl ... | 2006 | 16822273 |
| zoonotic implications of the swine-transmitted protozoal infections. | pig production is an important part of the economy in many countries. domestic and wild pigs (sus scrofa) are susceptible to a wide range of infectious and parasitic diseases. some of these diseases are specifically limited to pigs while some of the other diseases are shared with other species of wildlife and domestic livestock. as the numbers and geographic distribution of wild and domestic swines continue to increase, it is certain that the number of contacts between these swines and domestic ... | 2006 | 16828229 |
| pestiviruses in wild animals. | pestiviruses are not strictly host-species specific and can infect not only domestic but also wild animals. the most important pestivirus, csfv, infects domestic pigs and wild boars, which may cause a major problem for successful csfv eradication programmes. mainly bvdv specific antibodies have been reported in captive and free-living animals. virus has been isolated from some of these animal species, but since bvdv can contaminate cell cultures and foetal calf serum, early reports of bvdv isola ... | 2006 | 16839713 |
| first description and morphology of haemal nodes in piglets (sus scrofa domestica). | in this study, the presence of haemal nodes, previously recognised especially in ruminants, was determined for the first time in piglets. the morphology of haemal nodes located in the abdominal cavity of seven piglets was studied by gross inspection and by histological methods. haemal nodes reddish in colour and oval or round in shape were observed on the thin branches originating from the caudal and cranial mesenteric arteries. these nodes, having connection only with blood vessels, were covere ... | 2006 | 16841752 |
| effect of a short-acting no donor on bubble formation from a saturation dive in pigs. | it has previously been reported that a nitric oxide (no) donor reduces bubble formation from an air dive and that blocking no production increases bubble formation. the present study was initiated to see whether a short-acting no donor (glycerol trinitrate, 5 mg/ml; nycomed pharma) given immediately before start of decompression would affect the amount of vascular bubbles during and after decompression from a saturation dive in pigs. a total of 14 pigs (sus scrofa domestica of the strain norsk l ... | 2006 | 16857861 |
| [ultrastructural study of the pulmonary veins in pigs]. | to explore the possible relationship between the ultrastructural characteristics of pulmonary veins and the pathogenesis of atrial fibrillation originating from pulmonary veins. | 2006 | 16626553 |
| consumption of alcohol by sows in a choice test. | the domestic pig (sus scrofa domesticus) has been proposed as an animal model for human alcoholism because pigs have been observed to consume alcohol voluntarily to a state of intoxication and to exhibit tolerance and physical dependence. however, it has not been established whether pigs can develop psychological dependence on alcohol. we hypothesised that feed-restricted, stall-housed pregnant sows fed alcohol non-voluntarily for 5 weeks would develop a preference for alcohol and retain this pr ... | 2006 | 16631215 |