Publications

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pulmonary gas exchange and exercise performance in pulmonary hypertension.patients with pulmonary hypertension have disordered pulmonary gas exchange and impaired exercise tolerance. the hypoxemia is due to mild ventilation-perfusion (va/q) inequality exaggerated by the presence of a low mixed venous po2 (pvo2) and is accentuated during exercise due to a further fall in pvo2. this in turn may be worsened by vasodilators which increase the degree of va/q inequality. decreased exercise tolerance is due predominantly to cardiac limitation, and thus an improvement in card ...20144042731
[transient psychogenic concentric narrowing of the visual field]. 20144028220
[the prayer of the anxious patient]. 20143969750
naloxone causes urinary urgency.we present 2 cases in which naloxone, the opioid antagonist, produced urinary urgency. the mechanism of action and possible therapeutic applications are discussed.20143942028
gas chromatographic patterns of some apple surface wax constituents. 20144019626
cerebrospinal fluid vasopressin in neurological and psychiatric disorders.vasopressin was determined in csf and plasma of 243 patients with different neurological and psychiatric disorders, including control patients. csf vasopressin was significantly higher in patients with high pressure hydrocephalus, intracranial tumour, benign intracranial hypertension, intracranial haemorrhage, ischaemic stroke, and craniocerebral trauma. in patients with primary degenerative dementia, csf vasopressin was lower than in control patients. among patients with psychiatric disorders, ...20143973621
intraoperative autologous transfusion.intraoperative autologous transfusion is a technique that was first used almost 2 centuries ago but that has realized its potential only in the past 5 years. a growing national awareness of transfusion-related morbidity, of the need for alternative blood sources, and of improved methods for red blood cell recovery has led to an increased frequency of use of autologous transfusion. most hospital programs use semicontinuous flow centrifugation or canister technology for the intraoperative salvage ...20143919219
neuroblastoma and nutritional support: influence on the host-tumor relationship.the nutritional sequelae of neuroblastoma are secondary to tumor burden, tumor-host influenced metabolism, and antitumor operative, pharmacologic, and radiation therapy. nutritional support and its influence on the outcome of clinical cancer is confusing; but in a defined murine system, we hypothesized that whether or not nutritional repletion favors the host-tumor relationship is dependent on a nutritional augmentation of host antitumor immunity. c1300 murine neuroblastoma (nb) elicits a host a ...20143958885
[the pemphigoid allergodermia under the clinical picture of toxic epidermal necrolysis (lyell's syndrome)]. 20144237344
[pharmacologic therapy of angina pectoris]. 20144402001
[pharmacologic therapy of angina pectoris]. 20144402001
a principal components analysis of the kaufman assessment battery for children (k-abc): implications for the test results of children with learning disabilities. 20143950518
corporate and foundation support of "nontargeted" biological research in nonprofit institutions. 20143943129
[chemodectoma of the tongue: differential diagnostic and histogenetic criteria]. 20144325964
student nurses-or training--fewer or nurses. 20144118853
[treatment of chronic progressive polyarthritis and spondylarthritis ankylopoietica]. 20144294202
[treatment of chronic progressive polyarthritis and spondylarthritis ankylopoietica]. 20144294202
[mandibular osteosynthesis. conclusion]. 20144532294
superior vena caval syndrome: scintiphotographic evaluation of response to radiation therapy. 20144348248
superior vena caval syndrome: scintiphotographic evaluation of response to radiation therapy. 20144348248
[agenda for public health in the americas]. 20144249025
leonardo da vinci's views on arteriosclerosis. 20144601167
studies concerning metastasis formation and its chemotherapeutic prevention. 20144724881
studies concerning metastasis formation and its chemotherapeutic prevention. 20144724881
[methods of evaluating oral hygiene in children and juveniles]. 20144519465
[methods of evaluating oral hygiene in children and juveniles]. 20144519465
[erraneously diagnosed and treated knee injury]. 20144147865
[401 continuous series prostatectomies by r. denis' technic]. 20144117512
dispersion staining, dispersion, refractive indices in early enamel caries. 20144114197
[modern technics in dentistry and prosthodontics (iii). 3/4-crowns supported from the posterior side of the teeth]. 20144520716
[immunohistochemical studies using an enzyme-immunoglobulin conjugate. demonstration of in vivo bound immunoglobulins in lupus erythematosus, pemphigus vulgaris, pemphigus erythematosus and pemphigoid]. 20144102576
silver protein staining of nerve fibers in celloidin sections. 20144168292
computerized eeg pattern classification by adaptive segmentation and probability-density-function classification. description of the method.a phenomenological model for the representation of clinical eegs is proposed. it assumes each individual record to consist of a few repetitive patterns which are described sufficiently by their power spectra. an algorithm for automatic eeg evaluation is described. it consists of two steps, a segmentation process which isolates the elementary patterns, and a clustering procedure which groups similar patterns with each other. results are represented in graphical form. diagnostic classification is ...20144042635
severe chronic airflow obstruction: can corticosteroids slow down progression?a long-term (14-18 yr) prognostic study on patients with severe chronic airflow obstruction (cao) (fev1 less than 1000 ml) is reported. in 65 of the 79 patients under study at least 7 serial fev1 values were available. at the beginning of the study long-term treatment with oral prednisolone in doses of 10-15 mg/d was started. side-effects and introduction of inhalation corticosteroid therapy resulted in a decrease or complete cessation of oral corticosteroid treatment. three distinct patterns of ...20144054257
the mechanism of immunity in the light of current research. 20144159642
cerebral intravascular coagulation in diabetic ketoacidosis. 20144133643
rheumatic diseases in the community. 20144215069
surgery of the knee. 20143983070
pre-school children of amphetamine-addicted mothers. ii. environment and supportive social welfare.sixty-five children, whose 63 mothers took amphetamine during pregnancy, were followed prospectively with regard to their environmental conditions, during their first four years of life. nine of the 16 mothers, who gave up drug-taking in early pregnancy, were able to remain drug-free until their children reached four years of age. all but three of the remaining 47 mothers have continued to be addicts. twenty-two of 52 children (42%), who had initially been left in the care of their mothers, were ...20143993363
animal models of environmentally induced memory impairment. 20143925851
new techniques for the mass spectrometry of natural products. 20143896991
[septum deviation and concomitant sinusitis].it is generally assumed that there is a relation between nasal obstruction due to deformities of the nasal septum and disease of the paranasal sinuses. we investigated patients with septal deviation and rhinomanometrically determined nasal obstruction and checked the sinuses before septal surgery by radiography, ultrasonography, and endoscopy. the results of our investigation on 150 unselected patients during 1983 support the hypothesis. we found that non-invasive diagnostic methods, i.e. radiog ...20143910625
application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer.fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. these flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. i ...20143901789
child psychiatrists seen through pediatricians' eyes: results of a national survey. 20143968351
patients who sign against medical advice. 20143911241
[prevalence of gingivitis and dental caries. comparative study carried out in white brazilian school children of the rural zone of aracatuba]. 20144390642
[prevalence of gingivitis and dental caries. comparative study carried out in white brazilian school children of the rural zone of aracatuba]. 20144390642
[treatment of pertussis with hyperimmune gammaglobulin]. 20144112885
dentistry: a profession at the crossroad. 20144232325
the in vitro production of anti-dna antibody by cultured peripheral blood or tonsillar lymphoid cells from normal donors and sle patients.anti-dna antibody responses by cultured circulating lymphocytes from sle patients and by the tonsillar lymphoid cells of normal donors were detected and enumerated by a sensitive specific elisa of culture supernatants, or by a hemolytic anti-dna pfc assay. although spontaneous igm and igg anti-dna and anti-ssdna responses were characteristic of sle lymphocytes and spontaneous igm anti-ssdna responses were characteristic of tonsillar lymphocytes, the circulating lymphocytes of normal controls nev ...20143905965
preoperative radiation. 20144297395
prevalence of down's syndrome. 20144273167
colchicine-sensitive microtubules. 20144267164
ultrastructural features of the granulocytes in down's syndrome. 20144275399
ultrastructural features of the granulocytes in down's syndrome. 20144275399
androgens and androgen responsiveness in the feminizing testis syndrome. comparison of complete and "incomplete" forms. 20144252811
[function of the adrenal in rheumatic heart disease]. 20144300233
[observations on the article by h. schulze and h. haike: "on the increase in age of onset of juvenile osteochondrosis of the hip"]. 20144227932
[the treatment of bronchiolar obstruction (author's transl)]. 20144155789
automated serum calcium analyses corrected for dialysis effects. 20144629771
[celioscopy and female gonads (morphologic and functional correlation)]. 20144258846
preservation of sulphacetamide eye drops. 20144144887
electron paramagnetic resonance signal ii in spinach chloroplasts. ii. alternative spectral forms and inhibitor effects on kinetics of signal ii in flashing light. 20144360258
[experimental study of dolispan in the therapy of peptic ulcer]. 20144151718
intracellular complex carbohydrates in the normal and inflamed dental pulp. 20144129442
tumor-specific and allospecific immunogenicity of soluble extracts from chemically induced murine sarcomas. 20144136043
[teaching aids in basic clinical sciences (1): audiovisual tapes as an introduction to physical diagnosis]. 20144105565
technology in ambulatory medical care: cost increasing or cost saving?health insurers fear that increased use of medical technology in ambulatory care results in increased billings per physician. this view may overlook certain subtle links between available, appropriated technology in ambulatory practice and the propensity to hospitalize a marginal patient. in this paper, the impacts of technology on four components of total per physician treatment cost were analyzed statistically using 1976-1978 percentage changes for a sample of more than 700 swiss physicians: n ...20144081817
blood banking in the united states--1981.combined data from the american association of blood banks, american national red cross, and community council of blood centers for 1981 compared to similar data for 1980 show an increase in the collection and use of blood and components. in 1981, a greater percent of donor units was converted to multiple components. use of blood resources was more efficient in 1981 than in 1980.20144024226
polymorphic metabolism of metoprolol: clinical studies.after a single 200 mg oral dose of metoprolol tartrate the mean metoprolol auc was found to be six-fold higher in poor metabolizers (pms) of debrisoquine than in extensive metabolizers (ems). this was associated with impaired metabolic clearance via alpha-hydroxylation and o-dealkylation. a population study (n = 143) has shown a bimodal distribution in the ratio of metoprolol: alpha-hydroxymetoprolol recovered in urine which was correlated highly with the debrisoquine metabolic ratio. nine per c ...20144054194
quantitative analysis of veralipride in plasma and urine by gas chromatography-mass spectrometry and gas chromatography with flame-ionization detection.a highly sensitive and selective quantitative assay for unchanged veralipride has been developed. the compound is extracted from alkalized samples (plasma or urine) with dichloromethane and converted to its trimethylated derivative by reaction with trimethylanilinium hydroxide. the reaction mixture is then chromatographed on a 3% ov-1 column. trimethylated derivatives of plasma samples were assayed by selected-ion monitoring in the chemical-ionization mode and quantified by comparing the intensi ...20144019658
urinary retention secondary to ovarian dysgerminoma in a girl.a thirteen-year-old girl sought medical advice because of a markedly weakened urinary stream with severe hesitancy. she was referred to the pediatric clinic because of 3 episodes of acute urinary retention during a previous month. pelvic examination showed a retrovesical tumor. an excretory urogram revealed bilateral ureterectasis and pyelocalicectasis. two weeks after left nephrostomy, surgical exploration demonstrated a right ovarian mass causing compression of the left ureter and obstruction ...20144012986
[correlation between severity of haemolytic disease of the newborn and impairment of placental maturation (author's transl)]. 20144203350
[dispensary service to patients with dermatoses at the present stage]. 20143993218
a wilcoxon-type test for trend. 20144089356
interpeak intervals of auditory brainstem response, interaural differences in normal-hearing subjects and patients with sensorineural hearing loss.abr recordings were made on 31 normal-hearing subjects and 253 patients with sensorineural hearing loss (86 patients with unilateral hearing loss, 61 patients with asymmetrical hearing loss, 34 patients with symmetrical hearing loss, 55 patients with noise-induced hearing loss and 17 patients in the late chronic stage of menière's disease). in the patient group with unilateral hearing loss, the mean interpeak interval (ipi) i-v was significantly shorter than in normal-hearing subjects. the inter ...20144023603
mitral valve prolapse in sickle cell disease: manifestation of a generalized connective tissue disorder.previous studies have shown an association of sickle cell disease with generalized connective tissue disorders such as pseudoxanthoma elasticum. we recently documented an unexpectedly high prevalence of mitral valve prolapse, a connective tissue disorder, in sickle cell disease. to investigate this association, skin biopsies were analyzed from 32 sickle cell disease patients, 11 of whom had mitral prolapse. total and type iii collagen, collagen solubility, and uronic acid were not different betw ...20143985003
detection of the c-myc oncogene product in testicular cancer.a set of monoclonal antibodies was constructed by immunising mice with peptide fragments of the c-myc oncogene product. one such antibody, myc 1-6e10 was shown to bind to a 62,000 dalton protein identifiable with the c-myc product (p62c-myc). the antigen recognised was not destroyed by paraffin wax embedding. myc 1-6e10 was used to characterise the distribution of p62c-myc in archival testicular tumour material. normal testes expressed only small amounts of p62c-myc. seminomas showed increased n ...20144027160
["feasible model attempts for new service forms". from the compensation insurance day 1968]. 20144235727
pathogenesis and treatment conceptualization of dentofacial malrelations as related to the pattern of occlusal relationship. 20144059242
biotin-dependent carboxylase deficiencies (propionyl-coa and pyruvate carboxylases). 20143925855
reduction of skeletal blood flow in paget's disease with disodium etidronate therapy.fourteen patients with paget's disease of bone were treated with disodium etidronate in doses of 5 to 7 mg/kg per day. skeletal blood flow (sbf), was measured by the modified 18f clearance technique of wootton et al. (1976) before treatment and again during treatment. in 10 patients restudied 3-4 months after the start of therapy, sbf had fallen by a mean of 21% of the initial value, and the individual differences correlated well with the individual reductions in serum alkaline phosphatase (r = ...20143922391
[the reliability of clinical, hormonal and ultrasonic examination in the diagnosis of extrauterine pregnancy]. 20143910266
[activity of killer cells in normal pregnancy]. 20144080357
recent advances in cardiac surgery.virtually all forms of congenital heart disease can be repaired or significantly palliated. the risk of surgery in infancy continues to decline, and many lesions are being routinely repaired at an early age. this may permit an improved functional result later in life. other recent advances include the arterial switch procedure for transposition of the great arteries, the palliative repair of hypoplastic left heart syndrome, and the increased application of the fontan procedure in patients with o ...20143897982
cerebral blood flow and brain atrophy correlated by xenon contrast ct scanning.correlations between cerebral blood flow (cbf) measured during stable xenon contrast ct scanning and standard ct indices of brain atrophy were investigated in the patients with senile dementia of alzheimer type, multi-infarct dementia and idiopathic parkinson's disease. compared to age-matched normal volunteers, significant correlations were found in patients with idiopathic parkinson's disease between cortical and subcortical gray matter blood flow and brain atrophy estimated by the ventricular ...20143879209
defects in pulsatile lh release in normally menstruating runners.intense physical exercise has been associated with reproductive dysfunction and menstrual cycles may be abnormal in a majority of women with a heavy training load. to determine whether training influenced pulsatile lh release, we measured lh pulse frequency, lh pulse amplitude and area under the curve over six hours during the early follicular phase of the menstrual cycle in four sedentary women and six eumenorrheic women runners with a training volume of at least 32 km per week. all three lh va ...20143972973
ultrastructure in septa in blastobotrys and sporothrix.transmission electron micrographs of septa in blastobotrys species invariably showed central micropores. septa of species of sporothrix, however, exhibited three types of pores: micropores which were central if single, or scattered; central simple pores with woronin bodies; dolipores. the results confirm the heterogeneity of the genus sporothrix.20144039913
the total structure of viomycin by sequential analysis. 20144346588
the total structure of viomycin by sequential analysis. 20144346588
[results of treatment of fractures of the proximal end of the humerus by poelchen's method]. 20144248776
[enzymatic evaluation of diseases in otorhinolaryngology]. 20144249059
chromosomes in the de lange syndrome. 20144121247
osteoid osteoma of the thoracic spine with surgical decompression aided by somatosensory evoked potentials. a case report. 20144049102
selective surgical management of neural tube malformations.the physical characteristics of 49 children with spina bifida cystica, survivors of a group subjected to selection for early surgery are compared with 39 children alive from an earlier unselected series, born in the 1960s, and reviewed retrospectively. sixteen children were also studied in whom the initial decision not to operate had been followed by survival and subsequent treatment. children selected for initial surgery have a significantly lower mortality than those not selected and their mob ...20144015145
[the product "essentiale" in therapy of acute epidemic hepatitis]. 20144136123
cerebral energy reserves and glycolysis in neural tissue of 6-aminonicotinamide-treated mice. 20144156048
detection of specific dna sequences with short biotin-labeled probes.we have developed a simple, general synthesis of nonradioactive dna probes in which biotin is attached to the 5'-terminal phosphate of an oligodeoxyribonucleotide 16 bases long via an ethylenediamine or hexamethylenediamine linker. the products are stable under normal hybridization conditions. they hybridize to target dna as efficiently as the underivatized oligodeoxyribonucleotide. color development, using a commercially available kit, is complete within 3 hr using the biotin-detection method. ...20144042814
masturbation and the male adolescent. 20144429008
masturbation and the male adolescent. 20144429008
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