Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| development of a recombinant antigen-based elisa for the sero-detection of porcine lymphotropic herpesviruses. | xenotransplantation using pigs as donor species carries a risk for the activation of latent porcine herpesviruses and potential transmission to the human recipient. the porcine lymphotropic herpesviruses (plhv-1, -2, -3) are widespread in domestic pigs and closely related to the human gammaherpesviruses, epstein-barr virus and kaposi sarcoma herpesvirus, causing lymphoproliferative disorders. plhv-1 has been associated with a porcine post-transplantation lymphoproliferative disorder (ptld), affe ... | 2008 | 19152663 |
| expression of vascular endothelial growth factor receptors coincide with blood vessel in-growth and reactive bone remodelling in experimental intervertebral disc degeneration. | to analyze immunohistochemically the localization of the vegf receptors in experimental intervertebral disc degeneration tissues in a pig model. | 2008 | 19210865 |
| modulation of porcine (sus scrofa domestica) and pheasant (phasianus colchicus) carbonyl reducing enzymes by anthelmintic therapy with flubendazole. | flubendazole (flu) is a widely administered benzimidazole anthelmintic indicated for the control of parasitic diseases in farm animals including pigs and pheasants. this study was designed to test the biotransformation of flu in control animals and animals treated with flu in recommended therapeutic doses. the activities of several pheasant and porcine hepatic and intestinal carbonyl reducing enzymes and their modulation by flu were also studied. twelve adult pheasant hens, approximately 1 year ... | 2008 | 19356067 |
| traditional zootherapeutic studies in india: a review. | the present study aims to review the zootherapeutic practices of the different ethnic communities of india. this work is also an attempt to present a list of animals' use for medicinal purposes by different communities of india. data were gathered from 15 published research papers of various authors on zootherapeutic studies in india from 2000 to 2007. approximately 109 animals and their 270 uses are reported in traditional medicine in different parts of india. of these, the highest numbers of a ... | 2008 | 18634551 |
| differentiation of european wild boar (sus scrofa scrofa) and domestic swine (sus scrofa domestica) meats by pcr analysis targeting the mitochondrial d-loop and the nuclear melanocortin receptor 1 (mc1r) genes. | this work describes the differentiation of european wild boar (sus scrofa scrofa) and domestic swine (sus scrofa domestica) meats by pcr targeting sequences from two molecular markers: the mitochondrial displacement loop (d-loop) region and the nuclear melanocortin receptor 1 (mc1r) gene. a polymorphic d-loop fragment (~270bp) was amplified and sequenced in a number of wild and domestic sus scrofa meat samples, to find a nucleotide region suitable for pcr-rflp analysis. sequence data showed the ... | 2008 | 22062284 |
| the amplitude spectrum area correctly predicts improved resuscitation and facilitated defibrillation with head cooling. | when systemic hypothermia was maintained before inducing cardiac arrest, the likelihood of successful defibrillation and meaningful survival was increased. when hypothermia is induced during cardiopulmonary resuscitation, mortality is also improved. with the introduction of the amplitude spectrum area as a predictor of the success of electrical defibrillation, we investigated the effect of preferential head cooling initiated coincident with cardiopulmonary resuscitation on amplitude spectrum are ... | 2008 | 20449903 |
| a comparison between head cooling begun during cardiopulmonary resuscitation and surface cooling after resuscitation in a pig model of cardiac arrest. | employing transnasal head-cooling in a pig model of prolonged ventricular fibrillation, we compared the effects of 4 hrs of head-cooling started during cardiopulmonary resuscitation with those of 8 hrs of surface-cooling started at 2 hrs after resuscitation on 96-hr survival and neurologic outcomes. | 2008 | 20449906 |
| intra-arrest rapid head cooling improves postresuscitation myocardial function in comparison with delayed postresuscitation surface cooling. | to compare resuscitation outcomes and myocardial function among intra-arrest head cooling, delayed surface cooling, and uncooled controls. | 2008 | 20449907 |
| neuroprotective effects of the inhalational anesthetics isoflurane and xenon after cardiac arrest in pigs. | neurologic outcome after cardiopulmonary resuscitation from cardiac arrest carries a poor prognosis and treatment options to ameliorate brain damage are limited. | 2008 | 20449916 |
| volumetric tracking tool using four-dimensional ct for image guided-radiation therapy. | to analyze lung vessel motion automatically, we developed computerized tracking software for multi-slice ct (msct) data. here, we evaluated the tracking accuracy in images of healthy porcine lungs obtained by 256 multi-slice ct (256-msct). a domestic pig was scanned with 256-msct under free breathing conditions. the 256-msct provides 128-mm scan coverage with a 0.5-mm slice thickness in a single rotation (1.0 s/rot). automatic tracking was performed by template matching, where volumes of interes ... | 2008 | 20821162 |
| ten years evidence-based high-tech acupuncture--a short review of peripherally measured effects. | since 1997, the research unit of biomedical engineering in anesthesia and intensive care medicine of graz medical university has been dealing with the demystification of acupuncture and examining, using non-invasive methods, how different stimulation modalities (manual needle acupuncture, laserneedle acupuncture and electro acupuncture) affect peripheral and central functions. laser is also an important instrument for acupuncture. one only needs to mention the treatment of children or of patient ... | 2007 | 18955279 |
| anomalous ion diffusion within skeletal muscle transverse tubule networks. | skeletal muscle fibres contain transverse tubular (t-tubule) networks that allow electrical signals to rapidly propagate into the fibre. these electrical signals are generated by the transport of ions across the t-tubule membranes and this can result in significant changes in ion concentrations within the t-tubules during muscle excitation. during periods of repeated high-frequency activation of skeletal muscle the t-tubule k+ concentration is believed to increase significantly and diffusive k+ ... | 2007 | 17509153 |
| beating heart aortic valve replacement using real-time mri guidance. | : the principal limitations of percutaneous techniques to replace the aortic valve are detailed visualization and durable prostheses. we report the feasibility of using real-time magnetic resonance imaging (mri) to provide precise anatomic detail and visual feedback to implant a proven bioprosthesis. | 2007 | 22436922 |
| rational intraabdominal pressure monitoring: how to do it? | intraabdominal hypertension (iah) is increasingly appreciated by intensivists as an important cause of organ dysfunction, even at pressure levels which were previously thought to be harmless. therefore, the goal of this review is to describe the different methods commonly used in clinical practice for intraabdominal pressure (iap) measurement, the advised methodology for each measurement method, and finally to give a rational approach for iap monitoring in daily clinical practice. | 2007 | 24881697 |
| efficacy of lyophilised c-strain vaccine after oral immunisation of domestic pigs and wild boar against classical swine fever: first results. | the aim of this study was to evaluate the efficacy of lyophilised c-strain vaccine in domestic pigs and wild boar after oral application. a new spherical bait form (diameter 3 cm) containing lyophilised vaccine virus and the recent vaccine baits were used for animal experiments. four vaccination groups were established in experiment 1 (group 1: recent liquid bait vaccine; group 2: spherical baits containing one dose of the lyophilised vaccine; groups 3 (domestic pigs) and 4 (wild boar): spherica ... | 2007 | 18077931 |
| the morphology of the inner ear from the domestic pig (sus scrofa). | the morphology of the hair cells of the inner ear end organs from the domestic pig (sus scrofa) have been studied using a combination of scanning and transmission electron microscopy (sem and tem), revealing hair cells from the cochlea and vestibule using a novel surgical and technical approach. this is the first time that the inner ear hair cells from s. scrofa have been studied, thus providing useful anatomical information on the morphology of the hair cells from the cochlea, saccule and utric ... | 2007 | 18045329 |
| efficacy and safety of pimecrolimus-eluting stents in porcine coronary arteries. | we aimed to evaluate an effective dosage and safety profile of pimecrolimus as an anti-inflammatory drug for drug-eluting stents. | 2007 | 18053948 |
| focal epidural cooling reduces the infarction volume of permanent middle cerebral artery occlusion in swine. | the protective effect against ischemic stroke by systemic hypothermia is limited by the cooling rate and it has severe complications. this study was designed to evaluate the effect of sbh induced by epidural cooling on infarction volume in a swine model of pmcao. | 2007 | 17254860 |
| microwave ablation with a single small-gauge triaxial antenna: in vivo porcine liver model. | to evaluate the performance of a 17-gauge triaxial antenna at microwave ablation in an in vivo porcine liver model. | 2007 | 17255414 |
| cp7_e2alf: a safe and efficient marker vaccine strain for oral immunisation of wild boar against classical swine fever virus (csfv). | wild boar are an important reservoir of classical swine fever virus (csfv) in several european countries, where most of the primary outbreaks in domestic pigs are directly related to the endemic disease situation in the wild boar population. oral immunisation has been introduced as an additional control measure to accelerate csf eradication in wild boar in germany since 1993. immunisation with an oral bait vaccine based on the conventionally attenuated live vaccine strain "c" proved to be safe a ... | 2007 | 17257713 |
| evaluation of the mechanical strength and patency of functional end-to-end anastomoses. | although many mechanical devices are being developed for functional end-to-end anastomosis (fetea), the best choice remains to be determined. the mechanical strength of each device is an important factor associated with anastomotic leakage. in turn, anastomotic patency is related to postoperative stenosis. this study examined the bursting pressure and circumference of several feteas. | 2007 | 17285383 |
| analysis of the physical properties of costal cartilage in a porcine model. | to determine the impact of interventions on the degree of warping of costal cartilage. | 2007 | 17224486 |
| post-resuscitation haemodynamics in a novel acute myocardial infarction cardiac arrest model in the pig. | although a considerable amount of promising experimental research has been performed on cardiopulmonary resuscitation, clinical data indicate an ongoing limited outcome in human beings. one reason for this discrepancy could be that experimental studies use healthy animals whereas most human beings undergoing cardiopulmonary resuscitation suffer from acute or chronic myocardial dysfunction. to overcome this problem, we sought to develop a new model of myocardial infarction, that is easy to perfor ... | 2007 | 17241498 |
| assessment of acute reperfused myocardial infarction with delayed enhancement 64-mdct. | objective: the purpose of this study was to evaluate the utility of delayed enhancement 64-mdct in the assessment of myocardial infarct size in a porcine model of acute reperfused myocardial infarction. ct can be used for noninvasive assessment of coronary artery stenosis, but to our knowledge, evaluation of myocardial viability in the subacute phase of acute myocardial infarction has not been validated. we performed delayed enhancement imaging on six domestic swine 5 days after reperfused acute ... | 2007 | 17242218 |
| mri-based safety evaluation of the ventrica magnetic coronary anastomotic system. | the ventrica magnetic vascular positioner system is a novel automatic anastomotic coupling device for distal coronary artery anastomosis. there is concern that enormous magnetic fields may negatively affect graft anastomosis or coronary artery blood flow, or that they may lead to disconnection of the magnetic ports. forty-five domestic swine (26.6 +/- 5.9 kg) underwent magnetic resonance imaging after a single ventrica anastomosis of the left internal mammary artery to the left anterior descendi ... | 2007 | 17244918 |
| patent foramen ovale: standards for a preclinical model of prevalence, structure, and histopathologic comparability to human hearts. | this study evaluated and standardized a patent foramen ovale (pfo) preclinical model in gross anatomic and histopathologic features. | 2007 | 17173313 |
| genetic characterisation of african swine fever viruses from outbreaks in southern africa (1973-1999). | african swine fever (asf) is a highly lethal and economically significant disease of domestic pigs in the southern african sub-region, where outbreaks regularly occur. there is anecdotal evidence suggesting that trans-boundary movement of infected animals may have played a role in precipitating widespread outbreaks in the past, however, since the 1970s outbreaks have generally been more localised, particularly in those countries where control of animal movement is strictly regulated. the origin ... | 2007 | 17174485 |
| subretinal posterior pole injury induces selective proliferation of rpe cells in the periphery in in vivo studies in pigs. | to study topographical differences in porcine retinal pigment epithelial (rpe) cell proliferation (1) in vivo, after experimental central surgical subretinal injury, and (2) in vitro. | 2007 | 17197554 |
| acetylcholine injection into the amygdala elicits vocalization in domestic pigs (sus scrofa). | in a pilot study we have injected the amygdala of five female pigs (age 8 weeks) with acetylcholine (ach, 5.5mum/20mul) and recorded short latency utterances. the evoked vocalizations displayed the characteristics of natural screams in sonagram appearance and hearing impression. quantitative analyses, too, revealed the similarity of the ach-evoked vocalizations with natural screaming. the results demonstrate for the first time that aversive vocalizations can be triggered by cholinergic amygdala ... | 2007 | 17215052 |
| progenitor cells from the porcine neural retina express photoreceptor markers after transplantation to the subretinal space of allorecipients. | work in rodents has shown that cultured retinal progenitor cells (rpcs) integrate into the degenerating retina, thus suggesting a potential strategy for treatment of similar degenerative conditions in humans. to demonstrate the relevance of the rodent work to large animals, we derived progenitor cells from the neural retina of the domestic pig and transplanted them to the laser-injured retina of allorecipients. prior to grafting, immunocytochemical analysis showed that cultured porcine rpcs wide ... | 2007 | 17218397 |
| low tube voltage improves computed tomography imaging of delayed myocardial contrast enhancement in an experimental acute myocardial infarction model. | we sought to evaluate the influence of tube voltage on the visualization of acute myocardial infarction (mi) in cardiac multislice spiral computed tomography (msct). | 2007 | 17220730 |
| prevalence of streptococcus suis genotypes in wild boars of northwestern germany. | invasive serotype 2 (cps2+) strains of streptococcus suis cause meningitis in pigs and humans. four case reports of s. suis meningitis in hunters suggest transmission of s. suis through the butchering of wild boars. therefore, the objective of this study was to investigate the prevalence of potentially human-pathogenic s. suis strains in wild boars. s. suis was isolated from 92% of all tested tonsils (n=200) from wild boars. a total of 244 s. suis isolates were genotyped using pcr assays for the ... | 2007 | 17085699 |
| a one-step, gel-based rt-pcr assay with comparable performance to real-time rt-pcr for detection of classical swine fever virus. | classical swine fever, a notifiable disease to the office international des epizooties (oie), is a highly contagious viral disease affecting both domestic pigs and wild boars. rapid, sensitive, and specific detection of the causing agent classical swine fever virus (csfv) is therefore essential for diagnosis and control of the disease. most protocols for gel-based pcr consist of two steps, reverse transcription followed by pcr. such a protocol is time consuming, laborious and more prone to conta ... | 2007 | 17123637 |
| chinese white rongchang pig does not have the dominant white allele of kit but has the dominant black allele of mc1r. | the mast/stem cell growth factor receptor (kit) and melanocortin receptor 1 (mc1r) mutations are responsible for coat color phenotypes in domestic pigs. rongchang is a chinese indigenous pig breed with a white coat color phenotype. to investigate the genetic variability of the kit and mc1r genes and their possible association with the coat color phenotype in this breed, a gene duplication and splice mutation of kit were diagnosed in a sample of 93 unrelated rongchang animals. the results show th ... | 2007 | 17150979 |
| porcine circovirus type 2 antibody detection in backyard pigs from mexico city. | pcv2 antibodies have been found in pigs from all continents. however, this finding has been mainly studied in domestic swine reared under intensive production conditions. mexico city, with a human population over 19 million in 2005, has both urban and rural areas. the pig production in its rural area is based on small family backyard farms. taking into account this rather unique form of rearing pigs, the objective of this study was to determine the seroprevalence in backyard pigs from the rural ... | 2007 | 17157886 |
| laparoscopic ice slurry coolant for renal hypothermia. | we assessed the safety and efficacy of microparticulate ice slurry for laparoscopic hypothermia during renal ischemia in a single kidney porcine model. | 2007 | 17162095 |
| enteric caliciviruses in domestic pigs in hungary. | caliciviruses closely related to human norovirus and sapovirus were recently detected in domestic pigs, causing discussions about the animal reservoir and the potential for zoonotic transmission to humans. to detect porcine caliciviruses, 17 fecal samples collected on two swine farms in southwestern hungary were tested by reverse transcription-polymerase chain reaction. three (17.6%) samples were positive for caliciviruses. this study confirms the presence of caliciviruses, both porcine sapoviru ... | 2007 | 17180626 |
| a history of normal plates, tables and stages in vertebrate embryology. | developmental biology is today unimaginable without the normal stages that define standard divisions of development. this history of normal stages, and the related normal plates and normal tables, shows how these standards have shaped and been shaped by disciplinary change in vertebrate embryology. the article highlights the normal plates of the development of the vertebrates edited by the german anatomist franz keibel (16 volumes, 1897-1938). these were a major response to problems in the relat ... | 2007 | 17183461 |
| marker vaccine strategies and candidate csfv marker vaccines. | classical swine fever (csf) is an economically important highly contagious disease of swine worldwide. classical swine fever virus (csfv) is its etiological agent, and the only natural hosts are domestic pigs and wild boars. although field csfv strains vary in the virulence, they all result in serious losses in pig industry. highly virulent field strains generally cause acute disease and high mortality; moderately virulent field strains raise subacute or chronic infections; postnatal infection b ... | 2007 | 16934915 |
| increased spatial vasa vasorum density in the proximal lad in hypercholesterolemia--implications for vulnerable plaque-development. | vasa vasorum (vv) neovascularization is associated with advanced and ruptured atherosclerotic lesions that occur predominantly within the proximal third of the lad. to investigate further the possible role of vv spatial distribution in determining this predominantly proximal location of complex lesions we analyzed the changes in vv spatial densities along the lad in early atherosclerosis. | 2007 | 16919638 |
| molecular identification of trichuris vulpis and trichuris suis isolated from different hosts. | trichuris suis was isolated from the cecum of two different hosts (sus scrofa domestica -- swine and sus scrofa scrofa -- wild boar) and trichuris vulpis from dogs in sevilla, spain. genomic dna was isolated and internal transcribed spacers (its)1-5.8s-its2 segment from the ribosomal dna (rdna) was amplified and sequenced using polymerase chain reaction techniques. the sequence of t. suis from both hosts was 1,396 bp in length while that of t. vulpis was 1,044 bp. its1 of both populations isolat ... | 2007 | 17004099 |
| molecular epidemiology of trichinella spp. in three baltic countries: lithuania, latvia, and estonia. | meat of domestic pigs and wild boars has been the significant source of emerged human trichinellosis in lithuania, latvia, and estonia over the past two decades. however, there is very little known on the occurrence of trichinella spp. in main wildlife reservoirs and its transmission in domestic and sylvatic cycles in these countries. the present study demonstrated considerably higher endemicity of trichinella spp. in main sylvatic reservoirs (28.9-42% in foxes (vulpes vulpes) and raccoon dogs ( ... | 2007 | 17013647 |
| evaluation of baculovirus-derived recombinant 53-kda protein of trichinella spiralis for detection of trichinella-specific antibodies in domestic pigs by elisa. | the complete gene encoding the 53-kda protein derived from trichinella spiralis was cloned and expressed using a baculovirus-based system. characterization of a purified fusion protein consisting of the 53-kda protein and the glutathione s-transferase protein showed unspecific reactivity with swine pre-immune serum in both enzyme-linked immunosorbent assay (elisa) and western blot analysis. subsequently, a purified c-terminal 6xhis-tagged 53-kda protein was used in an elisa. the evaluation of th ... | 2007 | 17016726 |
| nutrient losses from manure and fertilizer applications as impacted by time to first runoff event. | nutrient losses to surface waters following fertilization contribute to eutrophication. this study was conducted to compare the impacts of fertilization with inorganic fertilizer, swine (sus scrofa domesticus) manure or poultry (gallus domesticus) litter on runoff water quality, and how the duration between application and the first runoff event affects resulting water quality. fertilizers were applied at 35 kg p ha-1, and the duration between application and the first runoff event varied betwee ... | 2007 | 17029684 |
| dental and skeletal characterization of the br-1 minipig. | this study was designed to characterize the development of oral structures in the br-1 minipig and to compare these data with literature reports on domestic swine and other minipig lineages. twelve male minipigs were anesthetized and given physical and radiographic examinations. the presence and chronology of tooth eruption from 3 to 15 months of age were assessed, and the radiographic results were interpreted by two certified researchers, who obtained a high index of agreement (kappa>0.81). the ... | 2007 | 16376127 |
| identify the injury implements by sem/edx and icp-aes. | the forensic investigator is frequently confronted with the discrimination and deduction of injury implements, which is one of the most important physical testimonies in courts. the usual method used in actual cases is from points of morphology. in the forensic discrimination of injury implements, such as metal implements, the analysis and comparison of elements are expected to provide excellent results, and simultaneous multi-elemental analysis is required to analyze various kinds of elements. ... | 2007 | 16621384 |
| compound subretinal prostheses with extra-ocular parts designed for human trials: successful long-term implantation in pigs. | subretinal implants aim to replace photoreceptor function in patients suffering from degenerative retinal disease like retinitis pigmentosa by topically applying electrical stimuli in the subretinal space. this study-as a last step before upcoming human trials-explored a newly developed surgical technique for permanent implantation of complex subretinal implants with extra-ocular parts. | 2007 | 16645861 |
| genetic involvement in skin wound healing and scarring in domestic pigs: assessment of molecular expression patterns in (yorkshire x red duroc) x yorkshire backcross animals. | yorkshire, red duroc, and f1 (first-generation cross) pigs heal with normal, fibroproliferative/hypercontractile, and intermediate levels of scarring, respectively. the purpose of this study was to evaluate the healing phenotype of yorkshire x f1 backcross animals, to address the molecular basis for genetic transmission of the red duroc scarring phenotype. macroscopically and histologically, full-thickness wounds on backcross animals followed the yorkshire phenotype, with one exception; the back ... | 2007 | 16858423 |
| the pygmy hog is a unique genus: 19th century taxonomists got it right first time round. | the pygmy hog, sus salvanius, the smallest and rarest extant suid was first described as the only member of the genus porcula. it is currently regarded as member of the genus sus and a sister taxon of the domestic pig/eurasian wild boar (sus scrofa). phylogenetic analyses of 2316 bp from three mtdna loci (control-region, cytochrome b, 16s) by bayesian inference and statistical testing of alternative phylogenetic hypotheses all support the original classification of the pygmy hog as a unique genu ... | 2007 | 17905601 |
| the temperature-dependent viscoelasticity of porcine lumbar spine ligaments. | a uniaxial tensile loading study of 13 lumbar porcine ligaments under varying environmental temperature conditions. | 2007 | 17632382 |
| implication of cortisol and 11beta-hydroxysteroid dehydrogenase enzymes in the development of porcine (sus scrofa domestica) ovarian follicles and cysts. | this study investigated cortisol inactivation by 11beta-hydroxysteroid dehydrogenase (11beta hsd) enzymes in porcine granulosa cells from antral follicles at different developmental stages and in ovarian cysts. in granulosa cells, cortisol oxidation increased threefold with antral follicle diameter (p < 0.001). this trend was paralleled by a threefold increase in nadp(+)-dependent 11beta-dehydrogenase activity in granulosa cell homogenates with follicle diameter. intact granulosa cells from ovar ... | 2007 | 17636169 |
| rapid communication: transvaginal single-port notes nephrectomy: initial laboratory experience. | natural orifice translumenal endoscopic surgery (notes) using purpose-built equipment has never been applied to urologic surgery. herein, we present our initial experience with a trans-vaginal single-port notes nephrectomy. | 2007 | 17638562 |
| effects of commonly used hemostatic agents on the porcine collecting system. | topical hemostatic agents have been particularly useful for preventing bleeding in tubeless percutaneous nephrolithotomy. in the present study, we investigated the effect of gelatin matrix hemostatic sealant (floseal), fibrin glue (tisseel,), polyethylene glycol polymers (coseal), and bovine serum albumin/ glutaraldehyde (bioglue) in the pig urinary collecting system after injection through a percutaneous nephrostomy (pcn) tract. | 2007 | 17638564 |
| [gastro-entero anastomosis with flexible endoscope with the help of rare-earth magnets on biosynthetic model made of the gastrointestinal tract of slaughtered pigs]. | gastro-entero anastomosis with flexible endoscope with the help of rare-earth magnets on biosynthetic model made of the gastrointestinal tract of slaughtered pigs | 2007 | 17649852 |
| [monitoring of infectious diseases among wild boars]. | sixty-seven serum samples and 43 pathological material samples from wild boars, taken in 5 regions of russia and in the kharkov region of the ukraine in 2002 to 2005 were studied. wild boars in some regions of russia were shown to be carriers of aujeszky's disease virus, porcine parvovirus, porcine circovirus type 2, lymphotropic herpesvirus-1, porcine cytomegalovirus, mycoplasma hyopneumoniae and pasteurella multocida. the classical swine fever (csf) virus genome was detected by polymerase chai ... | 2007 | 17601049 |
| retrospective analyses of serum lipids and lipoproteins and severity of disease in 60co-irradiated sus scrofa domestica and macaca mulatta. | profound neutropenia that provides an opportunity for infections to develop into sepsis remains an important cause of morbidity and mortality in patients after irradiation. human clinical studies find extremely low concentrations of cholesterol (less than 120 mg/dl) associated with high risk of death in critically ill adult patients admitted to intensive care units. this retrospective study was initiated as part of separate investigations of radiation-induced acquired infections in 2 large anima ... | 2007 | 17605346 |
| infertile finnish yorkshire boars carry a full-length line-1 retrotransposon within the kpl2 gene. | the kpl2 gene is expressed predominantly in cells with cilia or flagella. we have previously demonstrated that a large intronic insertion in kpl2 is associated with immotile sperm cells and infertility in the domesticated pig (sus scrofa). to fully characterize the structure of the mutation, we have now cloned and sequenced the insertion. the data identified the presence of a long interspersed nuclear element-1 (line-1) encoding all activities required for retrotransposition, including a 5'-untr ... | 2007 | 17610085 |
| peptidergic and nitrergic innervation of the pineal gland in the domestic pig: an immunohistochemical study. | the presence and co-localization of vasoactive intestinal polypeptide (vip), peptide n-terminal histidine c-terminal isoleucine (phi), pituitary adenylate cyclase-activating peptide (pacap), somatostatin (som), calcitonin gene-related peptide (cgrp), substance p (sp) and the neuronal isoform of nitric oxide synthase (nos) were studied in neuronal structures of the pig pineal gland. paraformaldehyde-fixed pineals of 3-month-old gilts were sliced into serial cryostat sections, which were subjected ... | 2007 | 17617110 |
| arginine vasopressin during sinus rhythm: effects on haemodynamic variables, left anterior descending coronary artery cross sectional area and cardiac index, before and after inhibition of no-synthase, in pigs. | we have shown previously that arginine vasopressin (avp) given during sinus rhythm increases mean arterial blood pressure (map) and left anterior descending (lad) coronary artery cross sectional area. avp was assumed to result in vasodilatation via activation of the endothelial nitric oxide system. the purpose of the present study was to assess the effects of avp before and after no-inhibition. nine domestic pigs were instrumented for measurement of haemodynamic variables using micromanometer-ti ... | 2007 | 17621455 |
| a high utility integrated map of the pig genome. | the domestic pig is being increasingly exploited as a system for modeling human disease. it also has substantial economic importance for meat-based protein production. physical clone maps have underpinned large-scale genomic sequencing and enabled focused cloning efforts for many genomes. comparative genetic maps indicate that there is more structural similarity between pig and human than, for example, mouse and human, and we have used this close relationship between human and pig as a way of fa ... | 2007 | 17625002 |
| effects of intraluminal irradiation with holmium-166 for tips stenosis: experimental study in a swine model. | we wanted to evaluate the effectiveness of intraluminal irradiation with holmium-166 ((166)ho) for reducing the pseudointimal hyperplasia (pih) in the transjugular intrahepatic portosystemic shunt (tips) tract in a swine model. | 2007 | 17420630 |
| antioxidant vitamins induce angiogenesis in the normal pig kidney. | the effects of chronic supplementation with antioxidant vitamins on angiogenesis are controversial. the aim of the present study was to evaluate in kidneys of normal pigs the effect of chronic supplementation with vitamins e and c, at doses that are effective in reducing oxidative stress and attenuating angiogenesis under pathological conditions. domestic pigs were randomized to receive a 12-wk normal diet without (n = 6) or with antioxidant vitamins supplementation (1g/day vitamin c, 100 iu.kg( ... | 2007 | 17429028 |
| modified ileal conduit stoma: safety of freeing the mesenteric edge of the distal part of ileal conduits. | an ileal conduit is created in about half of all urinary diversions. difficulties in constructing an abdominal stoma in morbidly obese patients can be challenging, especially if the patient has a short mesentery. excessive traction on the mesentery in an attempt to pass the distal segment of ileum through the thick abdominal wall may result in ischemia of the whole segment blood supply. we evaluated the safety of freeing the terminal portion of the conduit from its mesentery to facilitate easy p ... | 2007 | 17655874 |
| comparison of novel tissue apposing device and standard anastomotic technique for vesicourethral anastomoses. | to evaluate a novel sutureless tissue apposing vesicourethral anastomosis (vua) device in a porcine model and compare it with standard laparoscopically sutured vua. | 2007 | 17656246 |
| vasopressin improves survival in a porcine model of abdominal vascular injury. | we sought to determine and compare the effects of vasopressin, fluid resuscitation and saline placebo on haemodynamic variables and short-term survival in an abdominal vascular injury model with uncontrolled haemorrhagic shock in pigs. | 2007 | 17659093 |
| melagatran for thromboprophylaxis after mechanical valve implantation: results in a heterotopic porcine model. | melagatran, the active form of ximelagatran, is a novel, direct thrombin inhibitor that does not have a narrow therapeutic window regarding hemorrhagic and thromboembolic events. we aimed to determine whether melagatran would be effective in preventing thrombus formation on heterotopically placed mechanical heart valves. | 2007 | 17662773 |
| patent foramen ovale closure by radiofrequency thermal coaptation: first experience in the porcine model and healing mechanisms over time. | percutaneous transcatheter patent foramen ovale (pfo) closure is now standard practice and may limit embolic complications for at least 10 years. implantable pfo closure devices may be complicated by thrombosis, infection, device fracture, or embolization. a novel strategy uses radiofrequency-based thermal energy to seal pfo membranes, with no implanted device. we successfully used this method and examined histopathologic events in swine to characterize safety and efficacy. | 2007 | 17664371 |
| intra-genotypic resolution of african swine fever viruses from an east african domestic pig cycle: a combined p72-cvr approach. | two of the 22 presently recognised african swine fever (asf) virus p72 genotypes are genetically homogeneous and are associated with domestic pig cycles. of these, genotype viii comprises just two p72 variants, designated 'a' and 'b' in this study, and is confined to four east african countries where it has caused numerous outbreaks between 1961 and 2001. in order to resolve relationships within this homogeneous genotype, the central variable region (cvr) of the 9rl open reading frame of 38 viru ... | 2007 | 17674176 |
| strategies for the elimination of taeniasis/cysticercosis. | advances in the field of neurocysticercosis continue to shape our understanding of the disease and our efforts to control it. several attempts have been made to eradicate the disease with active interventions such as changing domestic pig-raising practices, mass chemotherapy of porcine cysticercosis and taeniasis, selective detection and treatment of taeniasis, and community health education. moreover, ongoing progress in the diagnosis of taeniasis and the development of a porcine vaccine agains ... | 2007 | 17681546 |
| metric analysis of the upper space of the temporomandibular joint (tmj) in pigs (sus scrofa domestica) for evaluation of the pig as a model for arthroscopic tmj surgery. | minimally invasive arthroscopic surgery of the temporomandibular joint (tmj) is more technically demanding than procedures in larger joints. the acquisition of adequate arthroscopic skills for tmj surgery requires extensive specialized training that can hardly be obtained from patients. in order to introduce a proper animal model for tmj arthroscopy, this study focuses on the morphology of the upper joint cavity of pigs at different ages. plastic casts of the upper joint cavity were obtained fro ... | 2007 | 17695994 |
| species-specific visitation and removal of baits for delivery of pharmaceuticals to feral swine. | within the domestic swine industry there is growing trepidation about the role feral swine (sus scrofa) play in the maintenance and transmission of important swine diseases. innovative disease management tools for feral swine are needed. we used field trials conducted in southern texas from february to march 2006 to compare species-specific visitation and removal rates of fish-flavored and vegetable-flavored baits with and without commercially available raccoon (procyon lotor) repellent (trial 1 ... | 2007 | 17699086 |
| the prevalence, organ distribution and fertility of cystic echinoccosis in feral pigs in tropical north queensland, australia. | an investigation was carried out to study the prevalence of echinococcus granulosus hydatidosis in feral pigs (sus domesticus) in the charters towers region of tropical north queensland. data were collected from a total of 238 carcasses, which were hunted and shot in the burdekin river catchment area. organs of the abdominal, thoracic, and pelvic cavities were examined for the presence of hydatid cysts. in the laboratory, cysts and hydatid cyst fluids were examined under a stereoscopic binocular ... | 2007 | 17708154 |
| 11beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology. | 11beta-hydroxysteroid dehydrogenase (11betahsd) enzymes modulate the target cell actions of corticosteroids by catalysing metabolism of the physiological glucocorticoid (gc), cortisol, to inert cortisone. recent studies have implicated gcs in boar sperm apoptosis. hence, the objective of this study was to characterise 11betahsd enzyme expression and activities in the boar testis and reproductive tract. although 11betahsd1 and 11betahsd2 mrna transcripts and proteins were co-expressed in all tiss ... | 2007 | 17709565 |
| laparoscopic diagnostics of acute bowel ischemia using ultraviolet light and fluorescein dye: an experimental study. | the aim of the study was to show the diagnostic potential of laparoscopy using fluorescein dye and ultraviolet light in acute bowel ischemia. | 2007 | 17710051 |
| brain metabolism during a decrease in cerebral perfusion pressure caused by an elevated intracranial pressure in the porcine neocortex. | cranial hypertension coincides with a reduction in cerebral blood flow as well as in oxygen delivery and influences outcome. in this study, we monitored changes in energy-related metabolites in the porcine cortex during an increase of intracranial pressure (icp) and to determine the level at which damage occurs. | 2007 | 17717234 |
| hypothalamic neurons innervating fat tissue in the pig express leptin receptor immunoreactivity. | while leptin receptors have been found in both the autonomic ganglion neurons and the hypothalamic nuclei, studies dealing with the projections from the central nervous system to the adipose tissue have been conducted mainly in laboratory animals. therefore, the purpose of our study was to establish whether hypothalamic neurons are transsynaptically connected to adipose tissue depots in the pig, and if these neurons express leptin receptor immunoreactivity. pseudorabies virus (prv; bartha's k st ... | 2007 | 17720315 |
| the characteristics of head wounds inflicted by "humane killer" (captive-bolt gun)--a 15-year study. | the "humane killer" or captive-bolt gun, is the tool/weapon widely used in meat industry and private farmer households for slaughtering animal stock. out of 17,250 autopsies performed at the institute of forensic medicine in novi sad during the 15-year period (1991-2005), 29 cases of suicides and two homicides were committed by captive-bolt pistols. wounds inflicted by captive-bolt guns have specific morphological features, distinctive from wounds made by other kinds of hand firearms. selected f ... | 2007 | 17767661 |
| intestinal toxicity induced by 5-fluorouracil in pigs: a new preclinical model. | the goal of this study was to develop an animal model of intestinal injury induced by 5-fluorouracil (5-fu) in pigs. | 2007 | 17785971 |
| adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts. | vascular access dysfunction is a major problem in hemodialysis patients. only 50% of arteriovenous grafts (avgs) will remain patent 1 year after surgery. avgs frequently develop stenoses and occlusions at the venous anastomoses in the venous outflow tract. lumen diameter is not only determined by intimal thickening but is also influenced by remodeling of the vessel wall. vascular remodeling requires degradation and reorganization of the extracellular matrix by the degradation enzymes, matrix met ... | 2007 | 17826244 |
| promoter activity of the long terminal repeats of porcine endogenous retroviruses of the korean domestic pig. | porcine endogenous retroviruses (pervs) in the pig genome represent a potential risk of infection in pig-to-human transplantation and are transmitted vertically. the solitary long terminal repeat (ltr) elements of the pervs affect the replication properties of the individual viruses via their repeat sequences and by encoding a set of specific transcription factors. we examined the promoter activities of solitary ltr elements belonging to the perv-a and -b families of the korean domestic pig (kdp ... | 2007 | 17846510 |
| molecular characterization and temporal expression profiling of presenilins in the developing porcine brain. | the transmembrane presenilin (psen) proteins, psen1 and psen2, have been proposed to be the catalytic components of the gamma-secretase protein complex, which is an intramembranous multimeric protease involved in development, cell regulatory processes, and neurodegeneration in alzheimer's disease. here we describe the sequencing, chromosomal mapping, and polymorphism analysis of psen1 and psen2 in the domestic pig (sus scrofa domesticus). | 2007 | 17854491 |
| ancient dna, pig domestication, and the spread of the neolithic into europe. | the neolithic revolution began 11,000 years ago in the near east and preceded a westward migration into europe of distinctive cultural groups and their agricultural economies, including domesticated animals and plants. despite decades of research, no consensus has emerged about the extent of admixture between the indigenous and exotic populations or the degree to which the appearance of specific components of the "neolithic cultural package" in europe reflects truly independent development. here ... | 2007 | 17855556 |
| effects of epinephrine and vasopressin on cerebral microcirculatory flows during and after cardiopulmonary resuscitation. | both epinephrine and vasopressin increase aortic and carotid arterial pressure when administered during cardiopulmonary resuscitation. however, we recently demonstrated that epinephrine reduces cerebral cortical microcirculatory blood flow. accordingly, we compared the effects of nonadrenergic vasopressin with those of epinephrine on cerebral cortical microvascular flow together with cortical tissue po2 and pco2 as indicators of cortical tissue ischemia. | 2007 | 17855828 |
| efficacy and safety of absorbable metallic stents with adjunct intracoronary beta radiation in porcine coronary arteries. | absorbable metallic stents (ams) utilizing mg alloy carry advantages over permanent metallic stents because of their potential to eliminate stent thrombosis, chronic inflammation, or artifacts with noninvasive imaging. these stents, however, are associated with a modest degree of late recoil and intimal hyperplasia. the aim of the study was to test whether adjunct vascular brachytherapy (vbt) compared to ams alone can overcome these limitations. | 2007 | 17880333 |
| differential anti-influenza activity among allelic variants at the sus scrofa mx1 locus. | a promising way to oppose infectious challenges would be to improve the resistance of the target species through genetic selection. theoretically, a candidate gene is available against influenza viruses since a resistance trait was fortuitously discovered in the a2g mouse strain. this trait was demonstrated to be correlated with the expression of a specific isoform of the type i interferon (ifn)-dependent protein mx, an isoform coded by a specific allele at the mouse mx1 locus. two allelic polym ... | 2007 | 17316142 |
| bloodless laparoscopic liver resection using radiofrequency thermal energy in the porcine model. | the aim of this study was to assess the feasibility and safety of laparoscopic hepatectomy using radiofrequency (rf) thermal energy in a porcine model. fifteen female domestic pigs weighing 29.3 kg (range 25 to 35 kg) were used. five transversal abdominal incisions (3 of 1 cm and 2 of 0.5 cm) were made for the introduction of the video camera and the other laparoscopic instruments. with the porta hepatis not clamped, the liver was inspected and the preferred lobe each time was divided using rf ( ... | 2007 | 17318049 |
| sero-survey on aino, akabane, chuzan, bovine ephemeral fever and japanese encephalitis virus of cattle and swine in korea. | vector-borne arboviruses produce mild to severe symptoms in domestic animals. bovine ephemeral fever (bef), akabane, aino, and chuzan virus have been primarily attributed to reproductive disorders or febrile diseases in cattle, and japanese encephalitis virus (jev) is mainly associated with reproductive failures in swine. we investigated antibody titers from domestic swine against four bovine arboviruses (bef, akabane, aino, and chuzan virus) and from cattle against jev in korea. while the posit ... | 2007 | 17322773 |
| anesthesia for cardiovascular interventions and magnetic resonance imaging in pigs. | large animal models are still required for many experimental purposes. the aim of the current study was to define a viable narcotic procedure for experimental cardiovascular interventions and imaging in pigs. a total of 32 domestic pigs were used. animals received propofol, midazolam, and fentanyl as continuous intravenous infusion anesthesia for complex vascular interventions, angiographic x-ray imaging, and magnetic resonance imaging (mri). anesthesia was maintained for 6 to 10 h. the initial ... | 2007 | 17343350 |
| phylogeny and ancient dna of sus provides insights into neolithic expansion in island southeast asia and oceania. | human settlement of oceania marked the culmination of a global colonization process that began when humans first left africa at least 90,000 years ago. the precise origins and dispersal routes of the austronesian peoples and the associated lapita culture remain contentious, and numerous disparate models of dispersal (based primarily on linguistic, genetic, and archeological data) have been proposed. here, through the use of mtdna from 781 modern and ancient sus specimens, we provide evidence for ... | 2007 | 17360400 |
| genetic variability and evolution of hepatitis e virus. | hepatitis e virus (hev) is the sole member of the genus hepevirus in the family hepeviridae. hev is transmitted primarily by the fecal-oral route, and water-borne epidemics are characteristic of hepatitis e in many developing countries in asia, africa and latin america where sanitation conditions are suboptimal. accumulating lines of evidence indicate that hev-associated hepatitis also occurs domestically among individuals in industrialized countries, that there are animal reservoirs of hev such ... | 2007 | 17363102 |
| optical coherence tomography: a noninvasive method to assess wound reepithelialization. | accurate assessment of wound healing may require invasive tissue biopsies, limiting its clinical usefulness in humans. optical coherence tomography (oct) is a novel, high-resolution method using light reflection to obtain noninvasive cross sectional imaging of biological tissues. | 2007 | 17363766 |
| skin decontamination of mustards and organophosphates: comparative efficiency of rsdl and fuller's earth in domestic swine. | research in skin decontamination and therapy of chemical warfare agents has been a difficult problem due to the simultaneous requirement of rapid action and non-aggressive behaviour. the aim of this study was to compare the performance of two decontaminating systems: the canadian reactive skin decontaminant lotion (rsdl) and the fuller's earth (fe). the experiment was conducted with domestic swine, as a good model for extrapolation to human skin. rsdl and fe were tested against sulphur mustard ( ... | 2007 | 17370872 |
| microbubbles in the pulmonary artery generated during experimental hepatic radiofrequency ablation is correlated with increased pulmonary arterial pressure. | microbubbles in hepatic veins during hepatic radiofrequency (rf) ablation is a well-known observation. in this experimental study, we examined the association between microbubbles in the pulmonary artery and alterations in mean pulmonary arterial pressure (mpap) during hepatic rf ablation with a perfusion electrode system. | 2007 | 17377191 |
| assessment of the lapraty clip for facilitating reconstructive laparoscopic surgery in a porcine model. | to assess the efficacy, reliability, and performance of the lapraty clip (ltc) as a substitute for knot tying during reconstructive surgery in a porcine model. | 2007 | 17382183 |
| assessment of cu-ets as a pet radiopharmaceutical for evaluation of regional renal perfusion. | the copper(ii) complex of ethylglyoxal bis(thiosemicarbazone) (cu-ets) was evaluated as a positron emission tomography (pet) radiopharmaceutical for assessment of regional renal perfusion. | 2007 | 17383574 |
| advances in swine biomedical model genomics. | this review is a short update on the diversity of swine biomedical models and the importance of genomics in their continued development. the swine has been used as a major mammalian model for human studies because of the similarity in size and physiology, and in organ development and disease progression. the pig model allows for deliberately timed studies, imaging of internal vessels and organs using standard human technologies, and collection of repeated peripheral samples and, at kill, detaile ... | 2007 | 17384736 |
| cardiac effects of endothelin receptor antagonism in endotoxemic pigs. | myocardial depression in sepsis is frequently encountered clinically and contributes to morbidity and mortality. increased plasma levels of endothelin-1 (et-1) have been described in septic shock, and previous reports have shown beneficial effects on cardiovascular performance and survival in septic models using et receptor antagonists. the aim of the current study was to investigate specific cardiac effects of et receptor antagonism in endotoxicosis. sixteen domestic pigs were anesthetized and ... | 2007 | 17400719 |
| preweaning housing effects on behavior and physiological measures in pigs during the suckling and fattening periods. | the effect of the preweaning housing system on the stress response of pigs before weaning and during fattening was studied in 33 litters of domestic pigs. three preweaning housing systems were compared: barren crate (standard farrowing crate without straw), enriched crate (20% larger crate, with straw), and as a control, a farrowing pen (pen, 60% larger than the barren crate, with straw). at 25 d of age, pigs were tested with an isolation test and 1 d later with a human approach test (humant). p ... | 2007 | 17400972 |
| high prevalence of unusual genotypes of toxoplasma gondii infection in pork meat samples from erechim, southern brazil. | toxoplasmosis is the most common cause of infectious uveitis in brazil, with a higher frequency in the south of the country. we have collected samples from porcine tongue and diaphragm obtained in both large and small abattoirs and used molecular biological technique to determine the prevalence of infection and rflp analysis to type the parasites. seventeen out of 50 (34%) samples from the diaphragm and 33 out of 50 (66%) samples from the tongue demonstrated a positive pcr reaction for t. gondii ... | 2007 | 17401480 |
| is all ventricular fibrillation the same? a comparison of ischemically induced with electrically induced ventricular fibrillation in a porcine cardiac arrest and resuscitation model. | the standard porcine cardiac arrest model uses electrical induction of ventricular fibrillation. reported restoration of spontaneous circulation and survival rates in this model are as high as 90% for ventricular fibrillation durations of 7-10 mins, values substantially greater than rates in the clinical population (i.e., 20% to 30%). a high first shock success rate, infrequent refibrillation, and short times for restoration of spontaneous circulation are typical of the model. the purpose of thi ... | 2007 | 17414084 |