Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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key sites for p2x receptor function and multimerization: overview of mutagenesis studies on a structural basis. | p2x receptors constitute a seven-member family (p2x1-7) of extracellular atp-gated cation channels of widespread expression. because p2x receptors have been implicated in neurological, inflammatory and cardiovascular diseases, they constitute promising drug targets. since the first p2x cdna sequences became available in 1994, numerous site-directed mutagenesis studies have been conducted to disclose key sites of p2x receptor function and oligomerization. the publication of the 3-a crystal struct ... | 0 | 25439586 |