Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [frequency of chromosomes carrying endogenous retroviruses in the populations of domestic pig and wild boar]. | statistical analysis of the frequency of chromosomes carrying three types (a, b, and c) of porcine endogenous retroviruses (perv) was based on molecular-genetic testing of populations of domestic pigs and wild boars. domestic pigs were shown to have higher frequency of perv and haplotypes containing two and three types of perv than wild boars. | 2008 | 18727389 |
| post-resuscitation hemodynamics and relationship to the duration of ventricular fibrillation. | we have observed consistent hemodynamic patterns after restoration of spontaneous circulation (rosc) after ventricular fibrillation (vf) cardiac arrest. we sought to characterize the time-course of these patterns, and to determine whether these differed based on duration of the vf insult. | 2008 | 18573588 |
| caspase-3 activation and dna damage in pig skin organ culture after solar irradiation. | in the present study, a convenient and easy-to-handle skin organ culture was developed from domestic pig ears using polycarbonate transwell culture inserts in 12-well plate. this alternative model was then tested for its suitability in analyzing the short-term effects of a single solar radiation dose (from 55 to 275 kj.m(-2)). differentiation of the pig skin was maintained for up to 48 h in culture, and its morphology was similar to that of fresh human skin. solar irradiation induced a significa ... | 2008 | 18282184 |
| simulating the spread of classical swine fever virus between a hypothetical wild-boar population and domestic pig herds in denmark. | denmark has no free-range wild-boar population. however, danish wildlife organizations have suggested that wild boar should be reintroduced into the wild to broaden national biodiversity. danish pig farmers fear that this would lead to a higher risk of introduction of classical swine fever virus (csfv), which could have enormous consequences in terms of loss of pork exports. we conducted a risk assessment to address the additional risk of introducing and spreading csfv due to the reintroduction ... | 2008 | 18339438 |
| microwave ablation with triaxial antennas tuned for lung: results in an in vivo porcine model. | to prospectively determine in swine the size and shape of coagulation zones created in normal lung tissue by using small-diameter triaxial microwave antennas and to prospectively quantify the effects of bronchial occlusion and multiple antennas on the coagulation zone. | 2008 | 18292471 |
| nutritional skewing of conceptus sex in sheep: effects of a maternal diet enriched in rumen-protected polyunsaturated fatty acids (pufa). | evolutionary theory suggests that in polygynous mammalian species females in better body condition should produce more sons than daughters. few controlled studies have however tested this hypothesis and controversy exists as to whether body condition score or maternal diet is in fact the determining factor of offspring sex. here, we examined whether maternal diet, specifically increased n-6 polyunsaturated fatty acid (pufa) intake, of ewes with a constant body condition score around the time of ... | 2008 | 18541015 |
| selection in the making: a worldwide survey of haplotypic diversity around a causative mutation in porcine igf2. | domestic species allow us to study dramatic evolutionary changes at an accelerated rate due to the effectiveness of modern breeding techniques and the availability of breeds that have undergone distinct selection pressures. we present a worldwide survey of haplotype variability around a known causative mutation in porcine gene igf2, which increases lean content. we genotyped 34 snps spanning 27 kb in 237 domestic pigs and 162 wild boars. although the selective process had wiped out variability f ... | 2008 | 18245828 |
| bioavailability of heme iron in biscuit filling using piglets as an animal model for humans. | the objective of this work was to evaluate the bioavailability of heme iron added to biscuit filling. it comprised two stages: first, the development of the heme iron enriched biscuit filling; second, the evaluation of the bioavailability of the mineral in fattening piglets. two groups were selected randomly and fed: a) low iron feed and biscuits with heme iron supplemented filling; b) normal feed (with ferrous sulphate). weight and blood parameters were measured every fifteen days. averages wer ... | 2008 | 18311330 |
| long beneficial effects after lipo-prostaglandin e1 administration on the ischemic gastric tube in pigs. | lipo-prostaglandin e1 (pge1) is a new preparation of pge1 in which it is bound to lipids in order to slow pge1 release and delay its rate of metabolism. we investigated how long the beneficial effects of intravenous administration of lipo-pge1 on the ischemic gastric tube continue. the gastric tube was constructed using 15 domestic pigs under general anesthesia and saline, unmodified pge1 and lipo-pge1 were infused continuously at a rate of 0.05 microg/kg/min for 10 minutes. tissue blood flow (t ... | 2008 | 18564164 |
| development of the movement of the epiglottis in infant and juvenile pigs. | although backward folding of the epiglottis is one of the signal events of the mammalian adult swallow, the epiglottis does not fold during the infant swallow. how this functional change occurs is unknown, but we hypothesize that a change in swallow mechanism occurs with maturation, prior to weaning. using videofluoroscopy, we found three characteristic patterns of swallowing movement at different ages in the pig: an infant swallow, a transitional swallow and a post-weaning (juvenile or adult) s ... | 2008 | 18387794 |
| dynamic chemical characteristics of soil solution after pig manure application: a column study. | when manures from intensive livestock operations are applied to agricultural or vegetable fields at a high rate, large amounts of salts and metals will be introduced into soils. using a column leaching experiment, this study assessed the leaching potential of the downward movement of cu and zn as well as some salt ions after an intensive farm pig manure at rates of 0%, 5% and 10% (w/w) were applied to the top 20 cm of two different textured soils (g soil -sandy loam soil; h soil-silty clay loam ... | 2008 | 18576224 |
| renal injury and the application of polysaccharide hemospheres: a laparoscopic experimental model. | microporous polysaccharide hemospheres (mph) are hemostatic beads engineered from purified plant starch. mph accelerates the natural clotting cascade by concentrating clotting factors and proteins on their surface while absorbing aqueous and low molecular weight components from blood. the purpose of this study was to determine the efficacy of mph in achieving hemostasis in the setting of laparoscopic renal injury. | 2008 | 18578666 |
| plasmin-matrix metalloproteinase cascades in spinal response to an experimental disc lesion in pig. | proteinases were immunohistochemically stained to analyze degenerated discs and paradiscal tissues in comparison to contiguous control tissues in an experimental porcine model of intervertebral disc degeneration. | 2008 | 18404101 |
| snipork - a microarray of snps in candidate genes potentially associated with pork yield and quality - development and validation in commercial breeds. | snipork is an oligonucleotide microarray based on the arrayed primer extension (apex) technique, allowing genotyping of single nucleotide polymorphisms (snps) in genes of interest for pork yield and quality traits. apex consists of a sequencing reaction primed by an oligonucleotide anchored with its 5' end to a glass slide and terminating one nucleotide before the polymorphic site. extension with one fluorescently labeled dideoxynucleotide complementary to the template reveals the polymorphism. ... | 2008 | 18228175 |
| carbon dioxide contrast agent for ct arteriography: results in a porcine model. | to test the feasibility of carbon dioxide (co(2))-enhanced computed tomographic (ct)-arteriography in an animal model. | 2008 | 18589320 |
| acalculous and clostridial cholecystitis in a pig. | a 21-month-old domestic hanford pig (sus scrofa domestica) in a 1-year study for experimental myocardial infarction was euthanized at the end of the study. one week earlier, the animal had symptoms and elevated clinical chemistry results suggestive of hepatobiliary disease, which resolved after medical therapy. at necropsy, the gallbladder was markedly enlarged, discolored, and had a thickened wall. within the gallbladder, there was abundant friable green-brown material. a culture of the gallbla ... | 2008 | 18599865 |
| attenuating the defibrillation dosage decreases postresuscitation myocardial dysfunction in a swine model of pediatric ventricular fibrillation. | the optimal biphasic defibrillation dose for children is unknown. postresuscitation myocardial dysfunction is common and may be worsened by higher defibrillation doses. adult-dose automated external defibrillators are commonly available; pediatric doses can be delivered by attenuating the adult defibrillation dose through a pediatric pads/cable system. the objective was to investigate whether unattenuated (adult) dose biphasic defibrillation results in greater postresuscitation myocardial dysfun ... | 2008 | 18496405 |
| epidemiological survey of swine influenza a virus in selected wild boar populations in germany. | the aim of this study was to evaluate the epidemiological situation of swine influenza virus (siv) infections in different wild boar populations in germany based on a serological surveillance in some bundeslaender (federal states) in connection with virological investigations in wild boar shot in northern germany (mecklenburg-western pomerania, district of nordvorpommern). altogether, 1245 sera from wild boar were tested using the hemagglutination inhibition test. the established seroprevalence ... | 2008 | 18440732 |
| non-robotic thoracoscopic internal mammary artery preparation in the pig. a training model. | notwithstanding non-robotic, thoracoscopic preparation of the internal mammary artery (ima) is a difficult surgical task, an appropriate experimental training model is lacking. we evaluated the young domestic pig for this purpose. four domestic female pigs (30-40 kg body weight) were used for this study. bilateral thoracoscopic preparation of the ima was carried out under continuous, pressure controlled co(2) insufflation. a 30 degrees rigid thoracoscope was inserted through a 10-mm port in the ... | 2008 | 18502784 |
| domestic pigs have low susceptibility to h5n1 highly pathogenic avian influenza viruses. | genetic reassortment of h5n1 highly pathogenic avian influenza viruses (hpai) with currently circulating human influenza a strains is one possibility that could lead to efficient human-to-human transmissibility. domestic pigs which are susceptible to infection with both human and avian influenza a viruses are one of the natural hosts where such reassortment events could occur. virological, histological and serological features of h5n1 virus infection in pigs were characterized in this study. two ... | 2008 | 18617994 |
| development of real-time polymerase chain reaction assays for rapid detection and differentiation of wild-type pseudorabies and gene-deleted vaccine viruses. | the successful eradication of pseudorabies in u.s. domestic swine was accomplished through the use of glycoprotein e (ge) deleted modified live virus vaccines and an accompanying ge differential enzyme-linked immunosorbent assay (elisa). yet, pseudorabies virus (prv) was established in feral swine in the united states, becoming a potential reservoir of prv for infection of domestic swine and other native wildlife. a critical need for the current prv surveillance program in the united states is t ... | 2008 | 18599848 |
| the differences between venous air embolism and fat embolism in routine intraoperative monitoring methods, transesophageal echocardiography, and fatal volume in pigs. | venous air embolism (vae) or fat embolism (fe) may occur in similar clinical settings such as after multiple injuries or total hip replacement. we designed this study to observe the differences between vae and fe in routine intraoperative monitoring methods, transesophageal echocardiography (tee), and fatal volume in pigs. | 2008 | 18636024 |
| signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity. | cytokines play a pivotal role in allergy development through activating signaling mechanisms, such as the janus kinase/signal transducer and activator of transcription (stat) pathway, which controls the expression of numerous proinflammatory genes. | 2008 | 17981315 |
| cryopreservation of the germplasm of animals used in biological and medical research: importance, impact, status, and future directions. | molecular genetics and developmental biology have created thousands of new strains of laboratory animals, including rodents, drosophila, and zebrafish. this process will accelerate. a decreasing fraction can be maintained as breeding colonies; hence, the others will be lost irretrievably unless their germplasm can be cryopreserved. because of the increasingly critical role of cryopreservation, and because of wide differences in the success with which various forms of germplasm can be cryopreserv ... | 2008 | 17901073 |
| alkali-labile sites in sperm cells from sus and ovis species. | constitutive alkali-labile sites (alss) have been investigated using a protocol of dna breakage detection-fluorescence in situ hybridization (dbd-fish) in sperm cells from sus domesticus (pig), ovis gmelini musimon (mouflon) and ovis aries (sheep). the results were compared with those obtained using leucocytes from the same species. whole comparative genomic hybridization (w-cgh) showed that most of the constitutive alss in somatic and germ line cells in all species examined were constrained to ... | 2008 | 17651406 |
| topography of the porcine epicardiac nerve plexus as revealed by histochemistry for acetylcholinesterase. | the aim of the present study was to map the topography of the porcine epicardiac nerve plexus (enp) and to re-examine the total number and distribution of the porcine intracardiac ganglia and neurons. eleven juvenile pigs (sus scrofa domestica, 3-4 weeks of age) were examined employing histochemistry for acetylcholinesterase to reveal the enp on total hearts. the nerves entered porcine epicardium at five sites: (1) ventro-medially to the origin of the superior vena cava, (2) dorsally to the orig ... | 2008 | 18063424 |
| short-term effects of biocorrodible iron stents in porcine coronary arteries. | biocorrodible iron stents carry the potential to overcome limitations, such as chronic inflammation and premature recoil, posed by biodegradable polymer and magnesium alloy stents. this study aimed to test the safety and efficacy of biocorrodible iron stents in porcine coronary arteries. | 2008 | 18086136 |
| electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. | newer guidelines address the importance of effective chest compressions, citing evidence that this primary intervention is usually suboptimally performed during cardiopulmonary resuscitation. we therefore sought a readily available option for monitoring the effectiveness of chest compressions, specifically using the electrocardiogram. | 2008 | 18090357 |
| postresuscitation myocardial diastolic dysfunction following prolonged ventricular fibrillation and cardiopulmonary resuscitation. | postresuscitation myocardial dysfunction is one of the leading causes of early death after successful resuscitation from sudden death. however, the diastolic characteristics of postresuscitation myocardial dysfunction are not well defined. we therefore investigated the postresuscitation left ventricular diastolic function following prolonged cardiac arrest and subsequent cardiopulmonary resuscitation. | 2008 | 18090365 |
| a new device to simplify flexible endoscopic treatment of zenker's diverticulum. | endoscopic treatment of a zenker's diverticulum (zd) is challenged by maintaining a stable position and visual field. an oblique transparent cap and an overtube have been used with success. the porcine hypopharyngeal pouch is similar to a zd. while using the widespread emr device (wemr) in the esophagus, we realized that the design may be advantageous for treatment of a zd. | 2008 | 18155432 |
| variability and action mechanism of a family of anticomplement proteins in ixodes ricinus. | ticks are blood feeding arachnids that characteristically take a long blood meal. they must therefore counteract host defence mechanisms such as hemostasis, inflammation and the immune response. this is achieved by expressing batteries of salivary proteins coded by multigene families. | 2008 | 18167559 |
| epidemiology of trichinellosis in germany, 1996-2006. | the epidemiology of trichinellosis in germany was investigated by analyzing national surveillance data from 1996-2006. during this period, 95 laboratory-confirmed infections and 12 outbreaks were reported. the highest mean annual incidence was found in immigrants from southeast european countries (0.3 cases/100,000 vs. 0.01 cases/100,000 in the german population) with an incidence rate ratio of 26.0 (95% confidence interval 11.6-51.8). the predominant clinical symptom was muscle pain in 79 patie ... | 2008 | 18171103 |
| effect of liquid swine manure rate, incorporation, and timing of rainfall on phosphorus loss with surface runoff. | excessive manure phosphorus (p) application increases risk of p loss from fields. this study assessed total runoff p (tpr), bioavailable p (bap), and dissolved reactive p (drp) concentrations and loads in surface runoff after liquid swine (sus scrofa domesticus) manure application with or without incorporation into soil and different timing of rainfall. four replicated manure p treatments were applied in 2002 and in 2003 to two iowa soils testing low in p managed with corn (zea mays l.)-soybean ... | 2008 | 18178885 |
| bone regeneration in osseous defects-application of particulated human and bovine materials. | different bone substitute materials are used to manage the challenge of local bone loss subsequent to craniofacial reconstructive surgery. in this animal study we examined the de novo bone formation in bone defects after insertion of puros allograft of human origin or navigraft of bovine origin, and compared the regenerative potential of each material to that of autogenous bone. | 2008 | 18206408 |
| a subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels. | hyperpolarization-activated cyclic nucleotide-gated (hcn) channels contribute to stabilizing resting membrane potential, thus controlling neuron excitability. subclasses of nociceptive neurons differ in their excitability, therefore, these channels could be a distinguishing marker. we investigated isolated dorsal root ganglion neurons from a non-rodent species, the pig, sus scrofa domesticus. single labeling revealed capsaicin-induced cobalt-uptake in 54.3% and transient receptor potential v1 (t ... | 2008 | 18218331 |
| detection and surveillance for animal trichinellosis in gb. | the zoonotic disease trichinellosis is considered one of the re-emerging diseases with surveillance and control methods constantly gaining more importance worldwide. recent change in european union (eu) legislation introduces trichinella-free production, and the possibility of risk-based monitoring for trichinella in pigs. this has increased the role of wildlife surveillance programmes and their impact on protecting human health as well as highlighted the need for harmonised surveillance protoco ... | 2008 | 18160221 |
| prostasome-like vesicles stimulate acrosome reaction of pig spermatozoa. | the presence of small membranous particles characterizes the male genital fluids of different mammalian species. the influence of semen vesicles, denominated prostasomes, on sperm functional properties has been well documented in humans, but their biological activity is scarcely known in other species. the present work investigated prostasome-like vesicles in pig semen for their ability to interact with spermatozoa and to affect acrosome reaction. | 2008 | 18234073 |
| intravenous tezosentan improves gas exchange and hemodynamics in acute lung injury secondary to meconium aspiration. | meconium aspiration induces acute lung injury (ali) and subsequent pulmonary arterial hypertension (pah) which may lead to right ventricular failure. increase of endothelin-1, thromboxane-a, and phosphodiesterases are discussed molecular mechanisms. we investigated the intrapulmonary and hemodynamic effects of the intravenous dual endothelin a and b receptor blocker tezosentan and inhalational iloprost in a model of ali due to meconium aspiration. | 2008 | 17898997 |
| setup and dosimetry for exposing anaesthetised pigs in vivo to 900 mhz gsm mobile phone fields. | the aim of this study was a dosimetrical analysis of the setup used in the exposure of the heads of domestic pigs to gsm-modulated radio frequency electromagnetic fields (rf-emf) at 900 mhz. the heads of pigs were irradiated with a half wave dipole using three different exposure routines; short bursts of 1-3 s at two different exposure levels and a continuous 10-min exposure. the electroencephalogram (eeg) was registered continuously during the exposures to search for rf-emf originated changes. ... | 2008 | 18247366 |
| immunoglobulin light chain (igl) genes in zebrafish: genomic configurations and inversional rearrangements between (v(l)-j(l)-c(l)) gene clusters. | in mammals, immunoglobulin light chain (igl) are localized to two chromosomal regions (designated kappa and lambda). here we report a genome-wide survey of igl genes in the zebrafish revealing (v(l)-j(l)-c(l)) clusters spanning 5 separate chromosomes. to elucidate igl loci present in the zebrafish genome assembly (zv6), conventional sequence similarity searches and a novel scanning approach based on recombination signal sequence (rss) motifs were applied. rt-pcr with zebrafish cdna was used to c ... | 2008 | 18022691 |
| validation of two commercial real-time rt-pcr kits for rapid and specific diagnosis of classical swine fever virus. | two real-time rt-pcr kits, developed by lsi (taqvet csf) and adiagene (adiavet csf), obtained an agreement to be commercialised in france, subject to conditions, defined by the french classical swine fever (csf) national reference laboratory. the producers were asked to introduce an internal control to check the rna extraction efficacy. the different criteria assessed were sensitivity, "pestivirus specificity", reproducibility and ease of handling, using 189 different samples. these samples were ... | 2008 | 17913249 |
| concepts for visualization of multidirectional phase-contrast mri of the heart and large thoracic vessels. | multidirectional phase-contrast magnetic resonance imaging allows the acquisition of time-resolved velocity fields (vectors) of cardiac and vascular blood flow. its unique ability to provide vectorial flow information promises to give new insights into hemodynamic physiology. however, up to now appropriate and standardized procedures and software tools are missing to take advantage of all the information contained in the data. the objective of this work is to present a new versatile software too ... | 2008 | 18280934 |
| porcine circovirus type 2 (pcv2) viral components immunomodulate recall antigen responses. | porcine circovirus type 2 (pcv2) is a single-stranded circular dna virus infecting domestic pigs worldwide. interaction of this virus with the immune system apparently modulates the immune response of the host. in the present study, the implication of different components of pcv2 in the modulation of the immune response of the host were investigated by using pcv2 viral-like particles (vlps) and 16 novel oligodeoxyribonucleotides containing cpg motifs (cpg-odns) based on the pcv2 genomic sequence ... | 2008 | 18304652 |
| comparison of a novel one-step percutaneous nephrolithotomy sheath with a standard two-step device. | percutaneous nephrolithotomy (pcnl) is the treatment of choice for large renal calculi. the most widely used access sheath for pcnl involves two steps including placement of a high-pressure balloon catheter (hpbc) followed by advancement of a sheath over the balloon. a novel pcnl balloon/sheath combination (nss) has been developed that allows for both dilation and sheath placement in a single step. the objective of this study was to compare the safety and efficacy of the nss to the hpbc in a por ... | 2008 | 18308088 |
| use of a chitosan-based hemostatic dressing in laparoscopic partial nephrectomy. | an external chitosan-based hemostatic bandage has been used to control aggressive bleeding from traumatic injuries. this study was to evaluate the feasibility of using an internal chitosan dressing based on the external platform to control hemorrhage and urinary leakage by sealing off the parenchymal wound following laparoscopic partial nephrectomy (lpn) in a porcine model. | 2008 | 17932955 |
| indomethacin decreases optic nerve oxygen tension by a mechanism other than cyclo-oxygenase inhibition. | we investigated the effect of several non-steroidal anti-inflammatory drugs (nsaids), on the preoptic nerve oxygen tension (onpo2), as indomethacin previously has demonstrated a strong decreasing effect on onpo2. we tested whether these nsaids, like indomethacin, also reduce the increasing effect of dorzolamide on onpo2. | 2008 | 17965100 |
| detection and analysis of porcine circovirus type 1 in hungarian wild boars: short communication. | porcine circovirus type 1 (pcv1) is considered to be a non-pathogenic virus detected in cell cultures, vaccines or products used for cell culture preparations, all of them of porcine origin. serological evidence and genetic studies suggested that pcv1 was widespread in domestic pigs. the presence of pcv1 in wild boars in germany was also described using serological methods. this paper reports the first detection of pcv1 in hungarian wild boars. samples were collected at slaughterhouses and proce ... | 2008 | 18401965 |
| genetic imprinting of h19 and igf2 in domestic pigs (sus scrofa). | the genes insulin-like growth factor 2 (igf2) and h19 express paternally and maternally, respectively, in humans, mice, sheep, and cattle. additionally, igf2 has been shown to be regulated by at least four promoters in a tissue- or development-specific manner. in the domestic pigs, the promoter- and tissue-specific imprinting pattern of igf2 has not been well characterized, nor is the imprinting pattern of h19. in the present study, we identified two polymorphisms in each of igf2 (exons 2 and 9) ... | 2008 | 18228173 |
| pharmacological analyses of two naturally occurring porcine melanocortin-4 receptor mutations in domestic pigs. | the melanocortin-4 receptor (mc4r) is critical in regulating mammalian food intake and energy expenditure. numerous mutations in the mc4r gene have been identified from obese humans. so far two naturally occurring porcine mc4r (pmc4r) mutations, d298n and r236h, have been identified from various strains of pigs and d298n is being utilized as a genetic marker to screen performance traits of pigs. in this study, we performed functional analyses of pmc4r d298n and r236h, including their ligand bind ... | 2008 | 18262384 |
| conventional high pressure versus newly developed continuous-flow ureterorenoscope: urodynamic pressure evaluation of the renal pelvis and flow capacity. | we evaluated the pressure and flow relation of a newly developed continuous-flow ureterorenoscope (urs) in comparison with a common ureterorenoscope in an ex-vivo urinary tract model. | 2008 | 18419336 |
| development of a transoral fundoplication device and related experimental research. | this paper describes a device and surgical techniques developed between 1999 and 2003 to enable an entirely transoral approach to fundoplication. the endofundoplication system (efs) system consisted of a multifunctional flexible tube for oral introduction (18 mm) as the key component, with a specially designed retroverted grasper that was used to grasp the lower esophageal sphincter (les) area of the esophagus, for invaginating the les into the stomach and folding the gastric wall onto the wall ... | 2008 | 18270877 |
| neurocognitive performance after cardiopulmonary resuscitation in pigs. | to test the feasibility of a neurocognitive test based on operant conditioning in a porcine model of cardiac arrest and cardiopulmonary resuscitation. furthermore, to characterize the influence of different durations of cardiac arrest on cognitive performance and the accompanying neurohistopathological changes. | 2008 | 18431271 |
| prearrest administration of low-molecular-weight heparin in porcine cardiac arrest: hemodynamic effects and resuscitability. | both animal and human studies demonstrate activation of coagulation during cardiac arrest. prearrest anticoagulation is used routinely in many experimental studies. we studied the hemodynamic effects of prearrest anticoagulation with a low-molecular-weight heparin suitable for clinical use during cardiopulmonary resuscitation in pigs. | 2008 | 18431276 |
| cerebral cortical microvascular flow during and following cardiopulmonary resuscitation after short duration of cardiac arrest. | to examine changes in cerebral cortical macro- and microcirculation and their relationship to the severity of brain ischaemia during and following resuscitation from a short duration of cardiac arrest. | 2008 | 18280632 |
| comparison of a novel radially dilating balloon ureteral access sheath to a conventional sheath in the porcine model. | traditional ureteral access sheaths rely on tapered dilators and the dotter principle of axial force to gain access into the ureter. we compared the performance of a novel balloon expandable ureteral access sheath using radial dilatation with that of a conventional ureteral access sheath. | 2008 | 18355865 |
| tissue response to surgical energy devices. | there is little data available on the effects of energy-based surgical devices (esd) on tissues other than arteries and veins. as such, we quantified the lateral thermal damage associated with contemporary esd: the harmonic ace, a prototype bipolar device known as the gyrus trisector, the harmonic lcs-c5, and the ligasure v. | 2008 | 18289646 |
| cytokine mrna expression and pathological findings in pigs inoculated with african swine fever virus (e-70) deleted on a238l. | african swine fever virus (asfv) induces a variety of immune responses and clinical forms in domestic pigs. as it is the only member of the asfarviridae family, asfv encodes many novel genes not encoded by other virus families. among these genes, a238l may regulate the synthesis of pro-inflammatory cytokines, controlled mainly by nfkappab and nfat pathways. in this study, we inoculated two groups of pigs, one with the asfv highly virulent e-70 isolate, deleted on a238l gene, and the other group ... | 2008 | 18384883 |
| the contribution of social effects to heritable variation in finishing traits of domestic pigs (sus scrofa). | social interactions among individuals are ubiquitous both in animals and in plants, and in natural as well as domestic populations. these interactions affect both the direction and the magnitude of responses to selection and are a key factor in evolutionary success of species and in the design of breeding schemes in agriculture. at present, however, very little is known of the contribution of social effects to heritable variance in trait values. here we present estimates of the direct and social ... | 2008 | 18245326 |
| a comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. | continuous flow cultures of feral (culture fc) and domesticated (culture rpcf) pig gut microflora were established in steady state. cultures were continuously infused with 25 or 100 microg tylosin/ml and sampled at intervals to assess effects on total culturable anaerobes, bacteroides and enterococcus via plating to agar supplemented without or with 100 microg tylosin/ml, the latter to assess bacterial sensitivity to tylosin. endogenous tylosin-insensitive anaerobes within the cultures, while si ... | 2008 | 18260812 |
| production of transgenic and non-transgenic clones in miniature pigs by somatic cell nuclear transfer. | miniature pigs have been recognized as valuable experimental animals in various fields such as medical and pharmaceutical research. however, the amount of information on somatic cell cloning in miniature pigs, as well as genetically modified miniature pigs, is much less than that available for common domestic pigs. the objective of the present study was to establish an efficient technique of cloning miniature pigs by somatic cell nuclear transfer. a high pregnancy rate was achieved following tra ... | 2008 | 18296867 |
| robotic notes (natural orifice translumenal endoscopic surgery) in reconstructive urology: initial laboratory experience. | to present an initial experience with robotic natural orifice translumenal surgery (r-notes) in reconstructive urology using the da vinci surgical system. | 2008 | 18455769 |
| hepatitis e virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention. | hepatitis e virus (hev), the sole member of the genus hepevirus in the family of hepeviridae, is the major cause of several outbreaks of waterborne hepatitis in tropical and subtropical countries and of sporadic cases of viral hepatitis in endemic and industrialized countries. transmission of hev occurs predominantly by the fecal-oral route although parenteral and perinatal routes have been implicated. the overall death rate among young adults and pregnant women is 0.5-3% and 15-20%, respectivel ... | 2008 | 18297720 |
| potential for cavitation-mediated tissue damage in shockwave lithotripsy. | shockwave lithotripsy (swl) injures renal tissue, and cavitation has been reported to mediate some of these effects. much of the work characterizing the cavitation injury of swl has been performed in small animals or in vitro. we describe experiments that promote cavitation during swl and estimate the spatial distribution of the resulting hemorrhagic lesion in a large-animal (porcine) model of clinical lithotripsy. | 2008 | 18315482 |
| thermal effects of laparoscopic saline-enhanced radiofrequency cautery on renal parenchyma in a porcine model. | advances in the field of surgery have recently developed a number of devices and materials to improve surgical hemostasis. the effects of one such device, saline-cooled monopolar radiofrequency electrocautery, has been well scrutinized in splenic and hepatic applications. despite the utilization of this device in urologic surgery, the classification of the thermal effects has been poorly characterized to date. the purpose of this study was to discern the thermal characteristics of the device in ... | 2008 | 18315485 |
| production of viable cloned miniature pig embryos using oocytes derived from domestic pig ovaries. | for production of viable somatic cell nuclear transferred (scnt) miniature pig embryos, in vitro condition for controlling the quality of recipient oocytes derived from domestic pig ovaries should be evaluated. in the present study, to get information on optimal in vitro maturation (ivm) condition of oocytes, we investigated the effect of ivm duration of recipient oocytes on subsequent development of scnt miniature pig embryos, the maturation-promoting factor (mpf) activity in recipient oocytes ... | 2008 | 18352818 |
| rapid communication: robot-assisted notes nephrectomy: initial report. | natural orifice transluminal endoscopic surgery (notes) using the davinci robot (intuitive surgical, sunnyvale, ca) has never been applied to urologic surgery. here we present our initial experience with a combined transvaginal and transcolonic, single-port, robot-assisted notes nephrectomy. | 2008 | 18355143 |
| risk factors associated with renal parenchymal fracture during laparoscopic cryoablation. | to assess the risk factors for haemorrhage and renal fracture associated with renal cryoablation. | 2008 | 18485040 |
| chitosan hemostatic dressing for renal parenchymal wound sealing in a porcine model: implications for laparoscopic partial nephrectomy technique. | this study was to evaluate the feasibility of using a novel chitosan hemostatic dressing to control hemorrhage and urinary leakage by sealing off the parenchymal wound following lpn. | 2008 | 18402734 |
| myocardial cytokine il-8 and nitric oxide synthase activity during and after resuscitation: preliminary observations in regards to post-resuscitation myocardial dysfunction. | increases in serum cytokines have been reported after successful resuscitation from prolonged ventricular fibrillation (vf). pro-inflammatory cytokines can stimulate inducible nitric oxide synthase (inos) to produce excessive levels of nitric oxide (no). high levels of both myocardial inflammatory cytokines and nitric oxide levels can depress myocardial contractile function. we hypothesized that myocardial pro-inflammatory cytokines and inos activity would increase following successful resuscita ... | 2008 | 18359140 |
| diagnostic specificity of a real-time rt-pcr in cattle for foot-and-mouth disease and swine for foot-and-mouth disease and classical swine fever based on non-invasive specimen collection. | foot-and-mouth disease virus (fmdv) and classical swine fever virus (csfv) are highly contagious and can cause great economic losses when introduced into disease-free regions. accurate estimates of diagnostic specificity (sp) are important when considering the implementation of surveillance for these agents. the purpose of this study was to estimate diagnostic sp of a real-time reverse-transcriptase pcr assay developed for detection of fmdv in cattle and domestic swine and csfv in domestic swine ... | 2008 | 18499360 |
| isolation and characterisation of rhodococcus equi from submaxillary lymph nodes of wild boars (sus scrofa). | rhodococcus equi has been isolated from the submaxillary lymph nodes of domesticated pigs, but little is known about the presence of r. equi in wild boars. the aim of the study was the evaluation of the incidence of r. equi in wild boars and the characterisation of them. of 482 submaxillary lymph nodes of wild boars shot in 39 settlements throughout hungary, r. equi was isolated from 60 specimens, and plasmid types of 82 isolates were examined. the isolates were tested for the presence of 15-17- ... | 2008 | 18499361 |
| expression of vascular endothelial growth factor receptors coincide with blood vessel in-growth and reactive bone remodelling in experimental intervertebral disc degeneration. | to analyze immunohistochemically the localization of the vegf receptors in experimental intervertebral disc degeneration tissues in a pig model. | 2008 | 19210865 |
| the adult göttingen minipig as a model for chronic heart failure after myocardial infarction: focus on cardiovascular imaging and regenerative therapies. | porcine models have become increasingly popular in cardiovascular research. the standard farm pig rapidly increases in body weight and size, potentially confounding serial measurements of cardiac function and morphology. we developed an adult porcine model that does not show physiologic increases in heart mass during the study period and is suitable for long-term study. we compared adult minipigs with the commonly used adolescent yorkshire swine. myocardial infarction was induced in adult göttin ... | 2008 | 19149414 |
| bama miniature pigs (sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin. | the objective of this study was to demonstrate that bama miniature pigs are a suitable experimental animal model for the evaluation of drugs for man. to this end, in vitro lovastatin metabolism at the minipig liver microsomal level and in vivo pharmacokinetics were studied. results were compared with those obtained from humans. our data indicate that the main metabolites and enzyme kinetic parameters of lovastatin metabolism are similar in pigs and humans. triacetyloleandomycin, a specific inhib ... | 2008 | 19149415 |
| intraindividual comparison of image quality in mr urography at 1.5 and 3 tesla in an animal model. | experimental evaluation of image quality of the upper urinary tract in mr urography (mru) at 1.5 and 3 tesla in a porcine model. | 2008 | 19238642 |
| spatial distribution of taenia solium porcine cysticercosis within a rural area of mexico. | cysticercosis is caused by taenia solium, a parasitic disease that affects humans and rurally bred pigs in developing countries. the cysticercus may localize in the central nervous system of the human, causing neurocysticercosis, the most severe and frequent form of the disease. there appears to be an association between the prevalence of porcine cysticercosis and domestic pigs that wander freely and have access to human feces. in order to assess whether the risk of cysticercosis infection is cl ... | 2008 | 18846230 |
| evaluation of shape and size changes of bone and remodelled bone substitute after different fixation methods. | suitable tissue fixation is indispensable to histological analysis. this investigation, therefore, sought to evaluate changes of shape and size of bone specimens and remodelled bone substitute material following different fixation methods. mandibular bones of 9 pigs (sus scrofa domesticus) served as specimens. two mandibular premolars were extracted respectively and the extraction alveoli were filled with synthetic bone substitute material. the samples were collected after 70 days. fixation of 6 ... | 2008 | 19075329 |
| soft tissue integration in the neck area of titanium implants--an animal trial. | dental implant materials are required to enable good apposition of bone and soft tissues. they must show sufficient resistance to chemical, physical and biological stress in the oral cavity to achieve good long-term outcomes. a critical issue is the apposition of the soft tissues, as they have provided a quasi-physiological closure of oral cavity. the present experiment was performed to study the peri-implant tissue response to non-submerged (1-stage) implant installation procedures. two differe ... | 2008 | 19075332 |
| the environmental and public health risks associated with arsenical use in animal feeds. | arsenic exposures contribute significantly to the burden of preventable disease worldwide, specifically related to increased risks of cancer, diabetes, and cardiovascular disease. most exposures are associated with natural contamination of groundwater, which is difficult to mitigate when these sources are used for drinking water. an anthropogenic source of arsenic exposure stems from the widespread use of arsenical drugs in food-animal production in the united states and china, among many countr ... | 2008 | 18991934 |
| diffuse spectral fundus reflectance measured using subretinally placed spectralon. | the diffuse fundus reflectance and the spectral transmittance of the swine sensory retina was measured in vivo using intravitreal illumination. pars plana vitrectomy and intravitreal manipulations were performed on a female american yorkshire domestic swine. light from a scanning monochromator was coupled into a fiber optic intraocular illuminator inserted into the vitreous. a 1.93-mm(2) region of the illuminated fundus was imaged from an oblique illumination angle. multispectral retinal images ... | 2008 | 19021332 |
| platelets from diabetic pigs exhibit hypersensitivity to thrombin. | responses of platelets from diabetic and diabetic-hyperlipidemic pigs were studied. pigs were made diabetic with single dose of alloxan, which acts by selectively destroying insulin-producing pancreatic beta cells thus inducing type 1 diabetes. pigs were kept for 1 or 12 wk, during which thrombin-induced aggregation was monitored in washed platelets. the platelets showed increased sensitivity to aggregation within 1 wk of induction of diabetes. hyperlipidemia alone for 12 wk did not increase pla ... | 2008 | 19004374 |
| transvenous intramyocardial cellular delivery increases retention in comparison to intracoronary delivery in a porcine model of acute myocardial infarction. | clinical trials using intracoronary (ic) delivery of cells have addressed efficacy but the optimal delivery technique is unknown. our study aimed to determine whether transvenous intramyocardial (tvim) approach was advantageous for cellular retention in ami. | 2008 | 19012733 |
| ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study. | tachycardia often facilitates ischemic ventricular fibrillation (vf). | 2008 | 19034029 |
| isolation and characterization of perv-c env from domestic pig in korea. | clone perv-c (a3) env was isolated from the genomic dna of domestic pig (sus scrofa domesticus) in korea to investigate the molecular properties of perv-c. the nucleic acid homologies between the perv-msl (type c) reference and the perv-c(a3) clone was 99% for env, but a single base pair deletion was found in the transmembrane (tm) region of the env open reading frame. to examine the functional characteristics of truncated perv-c env, we constructed a replication-incompetent retroviral vector by ... | 2008 | 18955828 |
| notes: a review of the technical problems encountered and their solutions. | natural orifice translumenal endoscopic surgery (notes) is currently investigated and developed worldwide. in the past few years, multiple groups have confronted this challenge. many technical problems are encountered in this technique due to the currently available tools for this approach. some of the unique technical problems in notes include: blindly performed primary incisions; uncontrolled pneumoperitoneal pressure; no support for the endoscope in the abdominal cavity; inadequate vision; in ... | 2008 | 18721009 |
| evaluation of unmeshed and 1:1 meshed alloderm bolsters for stapled rectal anastomoses in a porcine model. | the major morbidity of colorectal anastomoses is leaks. the concept of staple-line reinforcement is a growing area of interest. in this study, we evaluated the feasibility and effect of utilizing alloderm to bolster end-to-end stapled rectal anastomoses in a porcine model. | 2008 | 18721018 |
| expression, cellular localization and antibody responses of the african swine fever virus genes b602l and k205r. | previously, we identified serological immunodeterminants of african swine fever virus (asfv), including pk205r and pb602l, without homologues in the database. pk205r is expressed as a 33-kd protein from 4 h post-infection onward, initially diffusely distributed throughout cells, and subsequently in viral factories. pk205r was not found in purified virus. both pk205r and pb602l are recognised by hyperimmune antisera from domestic pigs and bushpigs at late time points after infection, suggesting t ... | 2008 | 19011730 |
| development of a recombinant antigen-based elisa for the sero-detection of porcine lymphotropic herpesviruses. | xenotransplantation using pigs as donor species carries a risk for the activation of latent porcine herpesviruses and potential transmission to the human recipient. the porcine lymphotropic herpesviruses (plhv-1, -2, -3) are widespread in domestic pigs and closely related to the human gammaherpesviruses, epstein-barr virus and kaposi sarcoma herpesvirus, causing lymphoproliferative disorders. plhv-1 has been associated with a porcine post-transplantation lymphoproliferative disorder (ptld), affe ... | 2008 | 19152663 |
| [experimental study on a new method for colonoscopic closure of large-bowel perforations with the otsc clip]. | iatrogenic perforation of the colon during interventional endoscopic procedures, e.g., mucosectomy, is a problematic complication, as safe treatment often requires surgical repair. iatrogenic perforation of the colon is indeed a rare complication; however, given the increasing case numbers in interventional endoscopy it is of considerable practical relevance. the closure of perforations can be achieved with conventional endoscopic clips; however, these working channel based clips are often too s ... | 2008 | 18979620 |
| endothelin-1 is not predictive of ventricular ectopy or ventricular fibrillation during acute myocardial ischemia. | endothelin(et)-1 (et-1) increases after myocardial infarction and may have effects on myocardial function. et-1 has also been shown to affect the action potential (ap) which may be arrhythmogenic and predispose to ventricular fibrillation (vf). the effects of et-2 and et-3 are uncertain. we hypothesized that the ets increase during acute ischemia and that plasma levels are predictive of ischemically induced vf. thirty-four domestic swine underwent balloon occlusion of the proximal lad coronary a ... | 2008 | 18844577 |
| natural orifice translumenal endoscopic surgery (notes) renal cryoablation in a porcine model. | to present our laboratory experience with natural orifice translumenal endoscopic surgery (notes) renal cryoablation. | 2008 | 18778358 |
| optical coherence tomography and intravascular ultrasound imaging of bioabsorbable magnesium stent degradation in porcine coronary arteries. | absorbable metallic stents (ams) composed of magnesium alloy were designed to complete degradation within 90-120 days. among the potential advantages of these stents, when compared to conventional stents, are the elimination of late stent thrombosis, chronic inflammation, and artifacts during noninvasive imaging. | 2008 | 18928950 |
| the effect of continuous release of recombinant human epidermal growth factor (rh-egf) in chitosan film on full thickness excisional porcine wounds. | the purpose of this article is to evaluate the effect of continuously released recombinant human epidermal growth factor (rh-egf) in chitosan film in full thickness porcine wounds. a total of 10 domestic pigs (yorkshire species) weighing 18 to 22 kg between the ages of 50 to 60 days were used. the wounds were divided into 3 groups and treated selectively with rh-egf in chitosan film (egf 20 ug/wound/d), chitosan film without rh-egf, or remained as the control group. one hundred percent healing t ... | 2008 | 18812721 |
| continuous hemofiltration in pigs with hyperdynamic septic shock affects cardiac repolarization. | sepsis has been defined as the systemic host response to infection with an overwhelming systemic production of both proinflammatory and anti-inflammatory mediators. continuous hemofiltration has been suggested as possible therapeutic option that may remove the inflammatory mediators. however, hemodialysis and hemofiltration were reported to influence cardiac electrophysiologic parameters and to increase the arrhythmogenic risk. we hypothesize that sepsis affects electrophysiologic properties of ... | 2008 | 18936693 |
| the proinflammatory cytokine response following resuscitation in the swine model depends on the method of ventricular fibrillation induction. | a systemic inflammatory response has been reported following resuscitation from cardiac arrest. the purpose of this study was to compare the magnitude of the tumor necrosis factor-alpha (tnf-alpha) response in two different swine models of ventricular fibrillation (vf) arrest. | 2008 | 18785945 |
| restenosis is not associated with stent length in a pig model of coronary stent implantation. | the aim of this study was to determine if stent length is by itself a risk factor for intimal proliferation and restenosis. long lesions represent an independent risk factor for restenosis after coronary stent implantation. a longer stented segment might result in a higher probability of restenosis. | 2008 | 18810722 |
| finite element representation of bone substitute remodelling in the jaw bone. | the finite element (fe) method was originally developed on a physical basis for the computation of structure-mechanical problems. meanwhile, it has been widely applied to medical issues. this study sought a suitable method to build a fe model for remodelling processes in osseous defects supplemented with bone substitute material. for this purpose, the second right premolars were extracted from four pig mandibles (sus scrofa domesticus) and the extraction alveoli were provided with synthetic bone ... | 2008 | 18803527 |
| insect succession and decomposition patterns on shaded and sunlit carrion in saskatchewan in three different seasons. | a study was conducted on decomposition and insect succession in the prairie ecozone of saskatchewan in the year 2000. eighteen domestic pig carcasses (42-79 kg) were employed as human models for applications to future homicide investigations in this region. two major variables were considered including the effect of season and habitat (sun versus shade). research was conducted over 25 weeks, spanning three seasons: spring, summer and fall. ambient temperature, internal carcass temperature, fauni ... | 2008 | 18662603 |
| probing of actinobacillus pleuropneumoniae apxiiia toxin-dependent cytotoxicity towards mammalian peripheral blood mononucleated cells. | abstract: | 2008 | 19046441 |
| african swine fever virus isolate, georgia, 2007. | african swine fever (asf) is widespread in africa but is rarely introduced to other continents. in june 2007, asf was confirmed in the caucasus region of georgia, and it has since spread to neighboring countries. dna fragments amplified from the genome of the isolates from domestic pigs in georgia in 2007 were sequenced and compared with other asf virus (asfv) isolates to establish the genotype of the virus. sequences were obtained from 4 genome regions, including part of the gene b646l that enc ... | 2008 | 19046509 |