Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| endemic hepatitis e in two nordic countries. | antibodies against hepatitis e virus (anti-hev) were found in 248 swedish and danish patients between 1993 and 2007. most patients were symptomatic and tested for anti-hev due to travel abroad. among patients with known country of infection, most were infected in asia, mainly on the indian subcontinent. however, 29 patients were infected in europe, nine of these had hev igm and/or hev rna in serum. in sera from 65 of 141 tested patients hev rna could be detected, and 63 strains could be typed by ... | 2009 | 19442399 |
| recording diffusion responses from contralateral intercostal muscles after stimulus-triggered electromyography: refining a tool for the assessment of thoracic pedicle screw placement in an experimental porcine model. | a new stimulus-triggered electromyography (emg) test for detecting stimulus diffusion to contralateral intercostal muscles during thoracic pedicle screw placement was assessed in a porcine model. | 2009 | 19444052 |
| comparison of vascularized osteoperiosteal femur flaps and nonvascularized femur grafts for reconstruction of mandibular defects: an experimental study. | the aim of this study was to compare the vascularized osteoperiosteal femur flaps (vffs) and the nonvascularized femur grafts (nvfgs) for reconstruction of the mandibular defects of pigs. | 2009 | 19446201 |
| wound healing and the immune response in swine treated with a hemostatic bandage composed of salmon thrombin and fibrinogen. | we investigated the inflammatory response in pigs exposed to salmon fibrinogen/thrombin dressings. animals were exposed to the material in 3 ways: (a) thrombin and fibrinogen were injected intravenously, (b) dual full-thickness skin lesions were surgically created on the dorsal aspect of the swine and treated with the fibrinogen/thrombin bandage and a commercial bandage or (c) a fibrinogen/thrombin bandage was inserted through an abdominal incision into the peritoneal cavity. blood was collected ... | 2009 | 19449202 |
| prevention of vasa vasorum neovascularization attenuates early neointima formation in experimental hypercholesterolemia. | vasa vasorum (vv) neovascularization is a key feature of early atherosclerosis and adds substantial endothelial exchange-surface to the coronary vessel wall. thus, it is conceivable that vv neovascularization favors the entry of pro-inflammatory and pro-atherosclerotic blood components into the coronary vessel wall. we sought to investigate the effects of thalidomide (th), a potent anti-angiogenic drug on vasa vasorum (vv) neovascularization, vessel wall inflammation, and neointima formation in ... | 2009 | 19458984 |
| molecular taxonomy, phylogeny and biogeography of nematodes belonging to the trichinella genus. | studying parasites of the genus trichinella provides scientists of today many advantages. this is a group of zoonotic nematodes that circulates freely among wildlife hosts with one in particular, trichinella spiralis that is exceptionally well adapted to domestic swine. recent reports suggest that human infections from hunted animals are on the rise worldwide and numerous countries still experience problems with t. spiralis in their domestic food supplies. trichinella is a genus whose members ar ... | 2009 | 19460327 |
| meat juice as diagnostic sample for virological and serological diagnosis of classical swine fever. | the objective of this paper was to assess if meat juice is a suitable substrate for virological and serological diagnosis of classical swine fever (csf). fifty-six domestic pigs and 21 wild boars experimentally vaccinated and/or infected as well as 129 field samples from wild boars were involved in this study. meat juice from diaphragm, forequarter and hindquarter was used for investigations. csfv and viral rna were detected in meat juice between days 5 and 21 post infection (pi). animals which ... | 2009 | 19462640 |
| imaging of the midpalatal suture in a porcine model: flat-panel volume computed tomography compared with multislice computed tomography. | an investigation was conducted to compare the image quality of prototype flat-panel volume computed tomography (fpvct) and multislice computed tomography (msct) of suture structures. | 2009 | 19464211 |
| comparative analysis of solar radiation-induced cellular damage between ex vivo porcine skin organ culture and in vitro reconstructed human epidermis. | reconstructed human epidermis models (rhe) constitute an innovative alternative to study phototoxicity and photoprotection in the cosmetic industry. however, little information is currently available concerning the harmful effects of solar-simulated radiation (ssr) in these in vitro skin models. in this study, the phototoxic effects of a single acute ssr dose of 275 kj m(-2) were evaluated in a validated rhe model (from skinethic), and were compared with those obtained from an ex vivo skin organ ... | 2009 | 19467030 |
| trichuris suis and trichuris trichiura are different nematode species. | in this paper, a morphological and biometrical study by optical microscopy and scanning electronic microscopy (sem) of trichuris suis isolated from different hosts (sus scrofa domestica and sus scrofa scrofa) and trichuris trichiura isolated from chimpanzee, has been carried out. our results demonstrate the existence of typical pericloacal papillae in both species. biometrical parameters of t. suis and t. trichiura overlapped but males and females of t. trichiura tended to be shorter and thinner ... | 2009 | 19467214 |
| usefulness of mri to differentiate between temporary and long-term coronary artery occlusion in a minimally invasive model of experimental myocardial infarction. | the surgical technique employed to determine an experimental ischemic damage is a major factor in the subsequent process of myocardial scar development. we set out to establish a minimally invasive porcine model of myocardial infarction using cardiac contrast-enhanced magnetic resonance imaging (ce-mri) as the basic diagnostic tool. twenty-seven domestic pigs were randomized to either temporary or permanent occlusion of the left anterior descending artery (lad). temporary occlusion was achieved ... | 2009 | 19472001 |
| receptor activator of nuclear factor kappa b ligand in an experimental intervertebral disc degeneration. | this study was designed to clarify the role of the receptor activator of nuclear factor kappa b ligand (rankl) in the process of discus degeneration and spondylarthrosis. it was hypothesized that experimental discus lesion would initiate not only local bone remodelling but also increased osteoclast formation on a location remote to the injury site due to altered spinal biomechanics. it was speculated that these changes in vertebral bone remodelling could be reflected in an increased rankl expres ... | 2009 | 19473572 |
| isolation and fluorescence spectrum of cardiac myosin from pig heart. | cardiac myosin is the most abundant and bioactive protein presented in heart tissue. in this work, a simple method was described for preparation of high purity cardiac myosin for further research. with the use of a domestic pig left ventricle as the starting tissue, this method yielded 4.5 mg myosin per gram of wet tissue with a specific activity of 0.293 u/mg. the purification factor was 4.9-fold with an activity recovery of 42.1%. in addition, the investigation of fluorescence spectrum shown t ... | 2009 | 19475499 |
| remarkable sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen african swine fever virus. | heterocapsa circularisquama dna virus (hcdnav; previously designated as hcv) is a giant virus (girus) with a approximately 356-kbp double-stranded dna (dsdna) genome. hcdnav lytically infects the bivalve-killing marine dinoflagellate h. circularisquama, and currently represents the sole dna virus isolated from dinoflagellates, one of the most abundant protists in marine ecosystems. its morphological features, genome type, and host range previously suggested that hcdnav might be a member of the f ... | 2009 | 19860921 |
| tick-borne encephalitis from eating goat cheese in a mountain region of austria. | we report transmission of tick-borne encephalitis virus (tbev) in july 2008 through nonpasteurized goat milk to 6 humans and 4 domestic pigs in an alpine pasture 1,500 m above sea level. this outbreak indicates the emergence of ticks and tbev at increasing altitudes in central europe and the efficiency of oral transmission of tbev. | 2009 | 19861072 |
| the robust phylogeny of korean wild boar (sus scrofa coreanus) using partial d-loop sequence of mtdna. | in order to elucidate the precise phylogenetic relationships of korean wild boar (sus scrofa coreanus), a partial mtdna d-loop region (1,274 bp, nc_000845 nucleotide positions 16576-1236) was sequenced among 56 korean wild boars. in total, 25 haplotypes were identified and classified into four distinct subgroups (k1 to k4) based on bayesian phylogenetic analysis using markov chain monte carlo methods. an extended analysis, adding 139 wild boars sampled worldwide, confirmed that korean wild boars ... | 2009 | 19855937 |
| technical development and initial animal experience with a novel, uncovered, self-expanding, highly flexible aortic stent with improved side branch access. | to present a novel, uncovered, self-expanding aortic stent for use as a thoracoabdominal stent-graft extension to improve distal flow in aortic dissections complicated by malperfusion syndrome and to enhance the remodeling process in the abdominal aorta after thoracic endovascular aortic repair. | 2009 | 19842725 |
| review of african swine fever: transmission, spread and control. | african swine fever is one of the most important and serious diseases of domestic pigs. its highly contagious nature and ability to spread over long distances make it one of the most feared diseases, since its devastating effects on pig production have been experienced not only in most of sub-saharan africa but also in western europe, the caribbean, brazil and, most recently, the caucasus. unlike most diseases of livestock, there is no vaccine, and therefore prevention relies entirely upon preve ... | 2009 | 19831264 |
| cervical spinal cord therapeutics delivery: preclinical safety validation of a stabilized microinjection platform. | the current series represents a preclinical safety validation study for direct parenchymal microinjection of cellular grafts into the ventral horn of the porcine cervical spinal cord. | 2009 | 19834381 |
| detection of novel sequences related to african swine fever virus in human serum and sewage. | the family asfarviridae contains only a single virus species, african swine fever virus (asfv). asfv is a viral agent with significant economic impact due to its devastating effects on populations of domesticated pigs during outbreaks but has not been reported to infect humans. we report here the discovery of novel viral sequences in human serum and sewage which are clearly related to the asfarvirus family but highly divergent from asfv. detection of these sequences suggests that greater genetic ... | 2009 | 19812170 |
| international ring trial to detect anti-trichinella igg by elisa on pig sera. | to determine the reproducibility and robustness of an elisa to detect anti-trichinella igg in pig sera which was previously validated at the community reference laboratory for parasites (crlp), a ring trial was organized involving european and extra-european reference laboratories for trichinella. the sensitivity and specificity of the assay determined by the crlp validation resulted to be 100% and 98.29%, respectively. the assay was reproducible, moreover, based on the receiver-operator charact ... | 2009 | 19819075 |
| influence of portosystemic shunt on liver regeneration after hepatic resection in pigs. | the minimal amount of liver mass necessary for regeneration is still a matter of debate. the aim of the study was to analyze liver regeneration factors after extended resection with or without portosystemic shunt. | 2009 | 19794827 |
| transmissibility studies of vacuolar changes in the rostral colliculus of pigs. | histopathological examinations of brains from healthy pigs have revealed localised vacuolar changes, predominantly in the rostral colliculus, that are similar to the neuropil vacuolation featured in the transmissible spongiform encephalopathies and have been described in pigs challenged parenterally with the agent causing bovine spongiform encephalopathy (bse). feedstuff containing bse-contaminated meat and bone meal (mbm) may have been fed to pigs prior to the ban of mammalian mbm in feed of fa ... | 2009 | 19765298 |
| kisspeptin signaling in the brain. | kisspeptin (a product of the kiss1 gene) and its receptor (gpr54 or kiss1r) have emerged as key players in the regulation of reproduction. mutations in humans or genetically targeted deletions in mice of either kiss1 or kiss1r cause profound hypogonadotropic hypogonadism. neurons that express kiss1/kisspeptin are found in discrete nuclei in the hypothalamus, as well as other brain regions in many vertebrates, and their distribution, regulation, and function varies widely across species. kisspept ... | 2009 | 19770291 |
| measurement of ninhydrin reactive nitrogen influx into gravesoil during aboveground and belowground carcass (sus domesticus) decomposition. | carcass decomposition results in the release of nitrogenous compounds into associated soil. the current study investigated the release of ninhydrin reactive nitrogen (nrn) following burial (approximately 40 cm depth) and decomposition on the soil surface. also investigated was the lateral extent of nrn in gravesoil. nrn concentration increased significantly in gravesoil collected from the center of graves (approximately 20 cm depth) during the initial two months of burial. a similar finding was ... | 2009 | 19773138 |
| differing sperm ability to penetrate the oocyte in vivo and in vitro as revealed using colloidal preparations. | the penetration ability of boar (sus scrofa domestica) spermatozoa exposed to viscous preparations under in vivo and in vitro fertilization conditions has been examined. experiments involving induced ovulation in prepubertal animals and surgical insemination directly into the oviduct isthmus revealed an advantage of colloidal preparations. based on within-animal comparisons, the incidence of penetration was 100% using both spermatozoa suspended in a viscous preparation of plant extracts and sper ... | 2009 | 19744704 |
| influence of habitat and seasonal variation on wild mammal diversity and distribution with special reference to the trypanosoma brucei gambiense host-reservoir in bipindi (cameroon). | to evaluate the role of wildlife in the resurgence and perenisation of human african trypanosomiasis (hat), we investigated the influence of habitat and seasonal variations on the diversity and spatial distribution of wild mammals, with special reference to those recognised as potential host-reservoirs of trypanosoma brucei gambiense in bipindi (southwestern cameroon). to achieve this, we carried out transect surveys in four habitat types over two years. a total of 31 mammal species were recorde ... | 2009 | 19732737 |
| the use of a hypo-osmotic swelling (hos) test on sperm of the pig (sus scrofa domesticus), emu (dromaius novaehollandiae), asian elephant (elephas maximus), hamadryas baboon (papio hamadryas hamadryas), and central rock rat (zyzomys pedunculatus). | a hypo-osmotic swelling test using talp-hepes medium over a range of 50 to 300 mosm/kg was applied to sperm from domestic and endangered species. maximal responses of curling of the sperm tails were seen over a range of osmolalities for epididymal sperm from the pig (100 mosm/kg), hamadryas baboon (range 50-125 mosm/kg), and central rock rat (range 50-100 mosm/kg), and the ejaculated sperm from the emu (50 mosm/kg) and the asian elephant (range 75-150 mosm/kg). a solution of talp-hepes medium at ... | 2009 | 19734955 |
| arginine-vasopressin attenuates beneficial norepinephrine effect on jejunal mucosal tissue oxygenation during endotoxinaemia. | the objective of the present study was to investigate the effects of increasing doses of norepinephrine (ne) with or without arginine-vasopressin (avp) on intestinal oxygen supply and jejunal mucosal tissue oxygen tension in an acute endotoxic pig model. | 2009 | 19720610 |
| amphiregulin promotes the proliferation of trophoblast cells during preimplantation development of porcine embryos. | our objective was to investigate the effects of in vitro culture (ivc) medium supplemented with amphiregulin (areg) on the preimplantation embryonic development of porcine (genus: sus domestica, species: landrace) embryos derived from in vitro fertilization (ivf) and parthenogenetic activation (pa). in vitro fertilization and pa embryos at the 1-cell stage were cultured in ivc medium supplemented with 0, 0.5, 5, or 50 ng/ml areg for 7 d. there were significantly greater total numbers of cells in ... | 2009 | 19729194 |
| effects of stomach inflation on haemodynamic and pulmonary function during spontaneous circulation in pigs. | stomach inflation during mask ventilation is frequent, but the effects on haemodynamic and pulmonary function are unclear. we evaluated the effects of stomach inflation on haemodynamic and pulmonary function during spontaneous circulation in a porcine model. | 2009 | 19211181 |
| endoscopic closure of the natural orifice transluminal endoscopic surgery (notes) access site to the peritoneal cavity by means of transmural resorbable sutures: an animal survival study. | endoscopic closure of the transgastric access site is still a critical area of active research and development into natural orifice transluminal surgery (notes). to date, no endoscopic technique has utilized resorbable transmural sutures for closure of the notes gastrostomy. | 2009 | 19214896 |
| african swine fever virus. | african swine fever virus (asfv) is a large, intracytoplasmically-replicating dna arbovirus and the sole member of the family asfarviridae. it is the etiologic agent of a highly lethal hemorrhagic disease of domestic swine and therefore extensively studied to elucidate the structures, genes, and mechanisms affecting viral replication in the host, virus-host interactions, and viral virulence. increasingly apparent is the complexity with which asfv replicates and interacts with the host cell durin ... | 2009 | 19216435 |
| characterization and zoonotic potential of endemic hepatitis e virus (hev) strains in humans and animals in hungary. | hepatitis e virus (hev) is a common cause of acute, fecally transmitted hepatitis in developing countries. identification of hev in indigenous human infection and in domestic pig raising the possibility that hev infection is also a zoonosis. objectives/study design: molecular detection and epidemiology of hev in humans (south-east hungary) with acute hepatitis and in domestic (pig, cattle) and wild (boar and roe-deer) animals (countrywide) by elisa and rt-pcr. | 2009 | 19217346 |
| [molecular epidemiology of hepatitis e virus in hungary: endemic, food-borne zoonosis]. | hepatitis e virus (hev) is one of a common cause of acute, fecally transmitted hepatitis in developing countries. identification of hev in indigenous human infection and in domestic pig raises the possibility that hev infection is also a zoonosis. | 2009 | 19228570 |
| mechanical transmission of vesicular stomatitis new jersey virus by simulium vittatum (diptera: simuliidae) to domestic swine (sus scrofa). | biting flies have been suggested as mechanical vectors of vesicular stomatitis new jersey virus (family rhabdoviridae, genus vesiculovirus, vsnjv) in livestock populations during epidemic outbreaks in the western united states. we conducted a proof-of-concept study to determine whether biting flies could mechanically transmit vsnjv to livestock by using a black fly, simulium vittatum zetterstedt (diptera: simuliidae), domestic swine, sus scrofa l., model. black flies mechanically transmitted vsn ... | 2009 | 19960709 |
| [dynamics of heterozygosity and its correlation with fitness in a population of domestic pigs]. | variation of heterozygosity at 11 loci for blood group systems (erythrocyte antigens), occurred during 14 years in the domestic pig population of kemerovskaya breed is described. the two estimates computed for the population examined were represented by expected population heterozygosity, as a measure resistant to stochastic fluctuations, and individual heterozygosity, as a measure with the features of a quantitative trait. our results showed that relative fitness of genotypic classes, formed by ... | 2009 | 19947552 |
| animals to heal animals: ethnoveterinary practices in semiarid region, northeastern brazil. | animal-based remedies constitute an integral part of traditional medicine and this is true in brazil as well both in rural and urban areas of the country. due to its long history, zootherapy has in fact become an integral part of folk medicine in the country. the use of these natural resources for medical purposes, however, is not restricted to human diseases treatment, being also widely used for the treatment of animal illnesses. ethnoveterinary is a science that involves the popular practical ... | 2009 | 19941663 |
| comparison of two different forms of bovine-derived hydroxyapatite in sinus augmentation and simultaneous implant placement: an experimental study. | the aim of this study was to compare two different forms of bovine-derived hydroxyapatite (ha) in sinus augmentation and simultaneous implant placement. | 2009 | 19885412 |
| concentrations of lipoproteins in the serum of wild boar and lithuanian pig breeds followed by principal component and cluster analyses to demonstrate the differences among genotypes. | with the aim of evaluating serum cholesterol and triglyceride concentrations in lithuanian wild boar and lithuanian pig breeds, twelve gilts from three genotype groups were used in the experiment. only the concentration of high-density lipoprotein (hdl) was significantly higher in the serum of wild boar than in serum of domestic pig breeds (p < 0.05). factor loadings of the principal components (pcs) revealed that lipoproteins were positively related in pc1 for wild boars but associations betwee ... | 2009 | 19886266 |
| characterization of selected nutrients and bacteria from anaerobic swine manure lagoons on sow, nursery, and finisher farms in the mid-south usa. | swine (sus scrofa domestica) production in the mid-south usa comprises sow, nursery, and finisher farms. a 2007 packing plant closure started a regional shift from finisher to sow and nursery farms. changes in manure stored in lagoons and land-applied as fertilizer were expected but were unknown because nutrient and bacterial levels had not been characterized by farm type. the objectives of this study were to quantify selected nutrients and bacteria, compare levels by farm types, and project imp ... | 2009 | 19875798 |
| new records of calyptrate dipterans (fanniidae, muscidae and sarcophagidae) associated with the decomposition of domestic pigs in brazil. | the calyptrate dipterans are the most important decomposers of human cadavers. knowledge of their species and distribution are of great importance to forensic entomology, especially because of the enormous diversity in brazil. carcasses of domestic pigs (sus scrofa, l) were the experimental models used to attract calyptrates of forensic interest during the winters of 2006 and 2007 and the summers of 2006 and 2008. a total of 24,423 specimens from 44 species were collected (19 muscidae, 2 fanniid ... | 2009 | 19876568 |
| elicitation of broad ctl response against hiv-1 by the dna vaccine encoding artificial multi-component fusion protein multihiv--study in domestic pigs. | broad ctl response against hiv-1 is one factor that helps to control the viral replication. we have constructed a dna vaccine that encodes a large artificial fusion protein (multihiv) and shown it to be immunogenic in mice, swine and macaques. inbred mice revealed ctl response only against two epitopes due to limited mhc class i variability. to assess the quality of the ctl response we addressed this question in domestic swine. number of presented epitopes varied between 7 and 14 among the five ... | 2009 | 19879232 |
| role of wild suids in the epidemiology of african swine fever. | there is presently no vaccine to combat african swine fever (asf), a viral hemorrhagic fever of domestic pigs that causes up to 100% morbidity and mortality in naive, commercial pig populations. in its endemic setting, asf virus cycles between asymptomatic warthogs and soft ticks, with persistence in exotic locations being ascribed to the almost global distribution of susceptible soft tick and suid hosts. an understanding of the role played by diverse hosts in the epidemiology of this multi-host ... | 2009 | 19915917 |
| indirect estimation of porcine parvovirus maternal immunity decay in free-living wild boar (sus scrofa) piglets by capture-recapture data. | linear mixed regression and logspline density estimation were performed to estimate the survival curve and half life of passively acquired antibodies against porcine parvovirus (ppv) in 44 wild boar piglets captured in the northern apennines, italy. one piglet had no detectable maternal antibodies at 2.5 months post partum and no antibodies were detected in any of the remaining piglets by 4 months of age. fitted survival curves indicated that maternal antibodies were undetectable from 2.5 to 6 m ... | 2009 | 18295517 |
| production of transgenic and non-transgenic clones in miniature pigs by somatic cell nuclear transfer. | miniature pigs have been recognized as valuable experimental animals in various fields such as medical and pharmaceutical research. however, the amount of information on somatic cell cloning in miniature pigs, as well as genetically modified miniature pigs, is much less than that available for common domestic pigs. the objective of the present study was to establish an efficient technique of cloning miniature pigs by somatic cell nuclear transfer. a high pregnancy rate was achieved following tra ... | 2008 | 18296867 |
| hepatitis e virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention. | hepatitis e virus (hev), the sole member of the genus hepevirus in the family of hepeviridae, is the major cause of several outbreaks of waterborne hepatitis in tropical and subtropical countries and of sporadic cases of viral hepatitis in endemic and industrialized countries. transmission of hev occurs predominantly by the fecal-oral route although parenteral and perinatal routes have been implicated. the overall death rate among young adults and pregnant women is 0.5-3% and 15-20%, respectivel ... | 2008 | 18297720 |
| porcine circovirus type 2 (pcv2) viral components immunomodulate recall antigen responses. | porcine circovirus type 2 (pcv2) is a single-stranded circular dna virus infecting domestic pigs worldwide. interaction of this virus with the immune system apparently modulates the immune response of the host. in the present study, the implication of different components of pcv2 in the modulation of the immune response of the host were investigated by using pcv2 viral-like particles (vlps) and 16 novel oligodeoxyribonucleotides containing cpg motifs (cpg-odns) based on the pcv2 genomic sequence ... | 2008 | 18304652 |
| comparison of a novel one-step percutaneous nephrolithotomy sheath with a standard two-step device. | percutaneous nephrolithotomy (pcnl) is the treatment of choice for large renal calculi. the most widely used access sheath for pcnl involves two steps including placement of a high-pressure balloon catheter (hpbc) followed by advancement of a sheath over the balloon. a novel pcnl balloon/sheath combination (nss) has been developed that allows for both dilation and sheath placement in a single step. the objective of this study was to compare the safety and efficacy of the nss to the hpbc in a por ... | 2008 | 18308088 |
| bioavailability of heme iron in biscuit filling using piglets as an animal model for humans. | the objective of this work was to evaluate the bioavailability of heme iron added to biscuit filling. it comprised two stages: first, the development of the heme iron enriched biscuit filling; second, the evaluation of the bioavailability of the mineral in fattening piglets. two groups were selected randomly and fed: a) low iron feed and biscuits with heme iron supplemented filling; b) normal feed (with ferrous sulphate). weight and blood parameters were measured every fifteen days. averages wer ... | 2008 | 18311330 |
| potential for cavitation-mediated tissue damage in shockwave lithotripsy. | shockwave lithotripsy (swl) injures renal tissue, and cavitation has been reported to mediate some of these effects. much of the work characterizing the cavitation injury of swl has been performed in small animals or in vitro. we describe experiments that promote cavitation during swl and estimate the spatial distribution of the resulting hemorrhagic lesion in a large-animal (porcine) model of clinical lithotripsy. | 2008 | 18315482 |
| thermal effects of laparoscopic saline-enhanced radiofrequency cautery on renal parenchyma in a porcine model. | advances in the field of surgery have recently developed a number of devices and materials to improve surgical hemostasis. the effects of one such device, saline-cooled monopolar radiofrequency electrocautery, has been well scrutinized in splenic and hepatic applications. despite the utilization of this device in urologic surgery, the classification of the thermal effects has been poorly characterized to date. the purpose of this study was to discern the thermal characteristics of the device in ... | 2008 | 18315485 |
| simulating the spread of classical swine fever virus between a hypothetical wild-boar population and domestic pig herds in denmark. | denmark has no free-range wild-boar population. however, danish wildlife organizations have suggested that wild boar should be reintroduced into the wild to broaden national biodiversity. danish pig farmers fear that this would lead to a higher risk of introduction of classical swine fever virus (csfv), which could have enormous consequences in terms of loss of pork exports. we conducted a risk assessment to address the additional risk of introducing and spreading csfv due to the reintroduction ... | 2008 | 18339438 |
| similarity of the swine vasculature to the human carotid bifurcation: analysis of arterial diameters. | we assessed the similarities of the iliac bifurcation in two breeds of swine to the known human carotid bifurcation, in order to assess its applicability as a preclinical model of the human carotid bifurcation. | 2008 | 18341957 |
| production of viable cloned miniature pig embryos using oocytes derived from domestic pig ovaries. | for production of viable somatic cell nuclear transferred (scnt) miniature pig embryos, in vitro condition for controlling the quality of recipient oocytes derived from domestic pig ovaries should be evaluated. in the present study, to get information on optimal in vitro maturation (ivm) condition of oocytes, we investigated the effect of ivm duration of recipient oocytes on subsequent development of scnt miniature pig embryos, the maturation-promoting factor (mpf) activity in recipient oocytes ... | 2008 | 18352818 |
| rapid communication: robot-assisted notes nephrectomy: initial report. | natural orifice transluminal endoscopic surgery (notes) using the davinci robot (intuitive surgical, sunnyvale, ca) has never been applied to urologic surgery. here we present our initial experience with a combined transvaginal and transcolonic, single-port, robot-assisted notes nephrectomy. | 2008 | 18355143 |
| comparison of a novel radially dilating balloon ureteral access sheath to a conventional sheath in the porcine model. | traditional ureteral access sheaths rely on tapered dilators and the dotter principle of axial force to gain access into the ureter. we compared the performance of a novel balloon expandable ureteral access sheath using radial dilatation with that of a conventional ureteral access sheath. | 2008 | 18355865 |
| myocardial cytokine il-8 and nitric oxide synthase activity during and after resuscitation: preliminary observations in regards to post-resuscitation myocardial dysfunction. | increases in serum cytokines have been reported after successful resuscitation from prolonged ventricular fibrillation (vf). pro-inflammatory cytokines can stimulate inducible nitric oxide synthase (inos) to produce excessive levels of nitric oxide (no). high levels of both myocardial inflammatory cytokines and nitric oxide levels can depress myocardial contractile function. we hypothesized that myocardial pro-inflammatory cytokines and inos activity would increase following successful resuscita ... | 2008 | 18359140 |
| expec-typical virulence-associated genes correlate with successful colonization by intestinal e. coli in a small piglet group. | upon studying the transmission of escherichia coli from a sow to five of her piglets, we observed domination of the coliform flora in piglets by a single e. coli clone, especially after weaning. this haemolytic cloneh1 did not harbour any virulence determinants typical for intestinal pathogenic e. coli isolates from swine but had a virulence gene profile very similar to extraintestinal e. coli (expec), including genes coding for p fimbriae and several iron acquisition systems, besides having an ... | 2008 | 18373678 |
| cytokine mrna expression and pathological findings in pigs inoculated with african swine fever virus (e-70) deleted on a238l. | african swine fever virus (asfv) induces a variety of immune responses and clinical forms in domestic pigs. as it is the only member of the asfarviridae family, asfv encodes many novel genes not encoded by other virus families. among these genes, a238l may regulate the synthesis of pro-inflammatory cytokines, controlled mainly by nfkappab and nfat pathways. in this study, we inoculated two groups of pigs, one with the asfv highly virulent e-70 isolate, deleted on a238l gene, and the other group ... | 2008 | 18384883 |
| development of the movement of the epiglottis in infant and juvenile pigs. | although backward folding of the epiglottis is one of the signal events of the mammalian adult swallow, the epiglottis does not fold during the infant swallow. how this functional change occurs is unknown, but we hypothesize that a change in swallow mechanism occurs with maturation, prior to weaning. using videofluoroscopy, we found three characteristic patterns of swallowing movement at different ages in the pig: an infant swallow, a transitional swallow and a post-weaning (juvenile or adult) s ... | 2008 | 18387794 |
| detection and analysis of porcine circovirus type 1 in hungarian wild boars: short communication. | porcine circovirus type 1 (pcv1) is considered to be a non-pathogenic virus detected in cell cultures, vaccines or products used for cell culture preparations, all of them of porcine origin. serological evidence and genetic studies suggested that pcv1 was widespread in domestic pigs. the presence of pcv1 in wild boars in germany was also described using serological methods. this paper reports the first detection of pcv1 in hungarian wild boars. samples were collected at slaughterhouses and proce ... | 2008 | 18401965 |
| chitosan hemostatic dressing for renal parenchymal wound sealing in a porcine model: implications for laparoscopic partial nephrectomy technique. | this study was to evaluate the feasibility of using a novel chitosan hemostatic dressing to control hemorrhage and urinary leakage by sealing off the parenchymal wound following lpn. | 2008 | 18402734 |
| plasmin-matrix metalloproteinase cascades in spinal response to an experimental disc lesion in pig. | proteinases were immunohistochemically stained to analyze degenerated discs and paradiscal tissues in comparison to contiguous control tissues in an experimental porcine model of intervertebral disc degeneration. | 2008 | 18404101 |
| conventional high pressure versus newly developed continuous-flow ureterorenoscope: urodynamic pressure evaluation of the renal pelvis and flow capacity. | we evaluated the pressure and flow relation of a newly developed continuous-flow ureterorenoscope (urs) in comparison with a common ureterorenoscope in an ex-vivo urinary tract model. | 2008 | 18419336 |
| bone regeneration after topical bmp-2-gene delivery in circumferential peri-implant bone defects. | the aims of this study were to evaluate the rate of bone formation and osseointegration after topical gene delivery with a liposomal vector system carrying bone morphogenetic protein (bmp)-2 cdna in combination with a collagen carrier and autologous bone as a carrier in freshly created peri-implant bone defects. | 2008 | 18422983 |
| neurocognitive performance after cardiopulmonary resuscitation in pigs. | to test the feasibility of a neurocognitive test based on operant conditioning in a porcine model of cardiac arrest and cardiopulmonary resuscitation. furthermore, to characterize the influence of different durations of cardiac arrest on cognitive performance and the accompanying neurohistopathological changes. | 2008 | 18431271 |
| prearrest administration of low-molecular-weight heparin in porcine cardiac arrest: hemodynamic effects and resuscitability. | both animal and human studies demonstrate activation of coagulation during cardiac arrest. prearrest anticoagulation is used routinely in many experimental studies. we studied the hemodynamic effects of prearrest anticoagulation with a low-molecular-weight heparin suitable for clinical use during cardiopulmonary resuscitation in pigs. | 2008 | 18431276 |
| influenza exposure in united states feral swine populations. | swine play an important role in the disease ecology of influenza. having cellular receptors in common with birds and humans, swine provide opportunities for mixed infections and potential for genetic reassortment between avian, human, and porcine influenza. feral swine populations are rapidly expanding in both numbers and range and are increasingly coming into contact with waterfowl, humans, and agricultural operations. in this study, over 875 feral swine were sampled from six states across the ... | 2008 | 18436668 |
| hybrid natural orifice translumenal surgery (notes) sleeve gastrectomy: a feasibility study using an animal model. | the indications for natural orifice translumenal surgery (notes) are yet to be determined. morbidly obese patients may be one population that would benefit from this approach due to the elimination of wound complications and possibly a faster recovery. as a bariatric restrictive procedure, sleeve gastrectomy could be one indication for notes. to test the feasibility of this procedure with a notes approach, a pig model was used. | 2008 | 18437477 |
| gene silencing of cd47 and antibody ligation of thrombospondin-1 enhance ischemic tissue survival in a porcine model: implications for human disease. | insufficient tissue perfusion underlies many acute and chronic diseases. tissue perfusion in turn requires adequate blood flow, determined in large part by the relative state of relaxation or constriction of arterial vessels. nitric oxide (no) produced by vascular cells modulates blood flow and tissue perfusion by relaxing and dilating arteries. recently, we reported that the secreted protein thrombospondin-1 (tsp1), through its cell surface receptor cd47, limits the ability of no to relax and d ... | 2008 | 18438125 |
| epidemiological survey of swine influenza a virus in selected wild boar populations in germany. | the aim of this study was to evaluate the epidemiological situation of swine influenza virus (siv) infections in different wild boar populations in germany based on a serological surveillance in some bundeslaender (federal states) in connection with virological investigations in wild boar shot in northern germany (mecklenburg-western pomerania, district of nordvorpommern). altogether, 1245 sera from wild boar were tested using the hemagglutination inhibition test. the established seroprevalence ... | 2008 | 18440732 |
| transcription analysis in the melim swine model identifies rack1 as a potential marker of malignancy for human melanocytic proliferation. | metastatic melanoma is a severe disease. few experimental animal models of metastatic melanoma exist. melim minipigs exhibit spontaneous melanoma. cutaneous and metastatic lesions are histologically similar to human's. however, most of them eventually spontaneously regress. our purpose was to investigate whether the melim model could reveal markers of malignancy in human melanocytic proliferations. | 2008 | 18442364 |
| imaging of the coronary venous system: validation of three-dimensional rotational venous angiography against dual-source computed tomography. | information on the anatomy of the cardiac venous system (cvs) is increasingly important for cardiac resynchronization therapy or percutaneous transvenous mitral valve annuloplasty. three-dimensional (3d) imaging can further improve the understanding of the relationship of cardiac structures. this study was performed to validate the accuracy of rotational coronary sinus angiography (csa) displaying the 3d anatomy of the cvs compared to ecg-gated, contrast-enhanced, cardiac dual-source computed to ... | 2008 | 18449597 |
| portal vein segmentation of a 3d-planning system for liver surgery--in vivo evaluation in a porcine model. | computer systems allow the planning of complex liver operations. the segmentation of intrahepatic vessels builds the basis for the calculation of liver segments and resection proposals. for surgical use, it is essential to know the capabilities and limitations of the segmentation. the aim of this study was to determine the sensitivity and precision of the portal vein segmentation of a computer planning system for liver surgery in vivo. | 2008 | 18449610 |
| influence of methylmalonyl-coa mutase alleles on resistance to bovine tuberculosis in the european wild boar (sus scrofa). | an association study was carried out to examine the influence of methylmalonyl-coa mutase (mut) polymorphisms on the susceptibility of a well-studied wild boar population from southern spain to develop bovine tuberculosis (btb). to this end, we examined polymorphisms at a closely linked dinucleotide microsatellite flanking exon 2 of the mut gene in 37 wild boars with btb and 36 non-infected individuals. the microsatellite showed low polymorphism in the studied population, with only three alleles ... | 2008 | 18454807 |
| robotic notes (natural orifice translumenal endoscopic surgery) in reconstructive urology: initial laboratory experience. | to present an initial experience with robotic natural orifice translumenal surgery (r-notes) in reconstructive urology using the da vinci surgical system. | 2008 | 18455769 |
| low levels of haptoglobin and putative amino acid sequence in taiwanese lanyu miniature pigs. | porcine haptoglobin (hp) is an acute phase protein. its plasma level increases significantly during inflammation and infection. one of the main functions of hp is to bind free hemoglobin (hb) and inhibit its oxidative activity. in the present report, we studied the hp phenotype of taiwanese lanyu miniature pigs (tly minipigs; n=43) and found their hp structure to be a homodimer (beta-alpha-alpha-beta) similar to human hp 1-1. interestingly, western blot and high performance liquid chromatographi ... | 2008 | 18460833 |
| foreign-body granulomas within intramyocardial arteries in a transcoronary safety assessment in pigs. | foreign-body granulomas within intramyocardial arteries were detected in three domestic pigs (sus scrofa domestica) in a routine transcoronary safety assessment study. the foreign bodies stained light grayish-blue by hematoxylin and eosin (h&e) and were strongly birefringent by polarized light microscopy. by their morphological features, they were identified as cotton fibers. embolization of foreign-body material into the myocardial arteries following catheter-based procedures is an unusual even ... | 2008 | 18467686 |
| transumbilical endoscopic cholecystectomy with the trichannel trocar technique: a porcine feasibility study. | the aim of this study is to verify the feasibility of another option: transumbilical endoscopic cholecystectomy by using the trichannel trocar technique. eight domestic pigs were submitted to transumbilical endoscopic cholecystectomy by using the trichannel trocar technique. a fine grasper of 2 mm in diameter was inserted through a small skin incision on the right upper abdomen for grasping the gallbladders. the natural scar of the umbilicus was restored after extract of the specimen. all the ga ... | 2008 | 18480087 |
| attainment of local drug delivery with paclitaxel-eluting balloon in porcine coronary arteries. | our purpose was to confirm the local drug delivery of a paclitaxel-eluting balloon by percutaneous intervention of single arterial segments or bifurcations of porcine coronary arteries. | 2008 | 18480668 |
| immediate post-shock chest compressions improve outcome from prolonged ventricular fibrillation. | this study was designed to test the hypothesis that immediate post-shock chest compressions improve outcome from prolonged ventricular fibrillation (vf) compared with typical "hands off" period (i.e., delayed post-shock compressions) associated with aed use. | 2008 | 18482786 |
| risk factors associated with renal parenchymal fracture during laparoscopic cryoablation. | to assess the risk factors for haemorrhage and renal fracture associated with renal cryoablation. | 2008 | 18485040 |
| prevalence of cryptosporidium genotypes in pre and post-weaned pigs in australia. | a total of 289 pig faecal samples were collected from pre-weaned and post-weaned piglets and sows from 1 indoor and 3 outdoor piggeries located in the south-west region of western australia and screened at the 18s rrna locus for the presence of cryptosporidium. an overall prevalence of 22.1% (64/289) was identified. cryptosporidium was more prevalent in post-weaned animals (p<0.05); 32.7% (51/156) versus 10.6% (13/123) for pre-weaned animals. sequence analysis identified cryptosporidium suis in ... | 2008 | 18486131 |
| attenuating the defibrillation dosage decreases postresuscitation myocardial dysfunction in a swine model of pediatric ventricular fibrillation. | the optimal biphasic defibrillation dose for children is unknown. postresuscitation myocardial dysfunction is common and may be worsened by higher defibrillation doses. adult-dose automated external defibrillators are commonly available; pediatric doses can be delivered by attenuating the adult defibrillation dose through a pediatric pads/cable system. the objective was to investigate whether unattenuated (adult) dose biphasic defibrillation results in greater postresuscitation myocardial dysfun ... | 2008 | 18496405 |
| diagnostic specificity of a real-time rt-pcr in cattle for foot-and-mouth disease and swine for foot-and-mouth disease and classical swine fever based on non-invasive specimen collection. | foot-and-mouth disease virus (fmdv) and classical swine fever virus (csfv) are highly contagious and can cause great economic losses when introduced into disease-free regions. accurate estimates of diagnostic specificity (sp) are important when considering the implementation of surveillance for these agents. the purpose of this study was to estimate diagnostic sp of a real-time reverse-transcriptase pcr assay developed for detection of fmdv in cattle and domestic swine and csfv in domestic swine ... | 2008 | 18499360 |
| isolation and characterisation of rhodococcus equi from submaxillary lymph nodes of wild boars (sus scrofa). | rhodococcus equi has been isolated from the submaxillary lymph nodes of domesticated pigs, but little is known about the presence of r. equi in wild boars. the aim of the study was the evaluation of the incidence of r. equi in wild boars and the characterisation of them. of 482 submaxillary lymph nodes of wild boars shot in 39 settlements throughout hungary, r. equi was isolated from 60 specimens, and plasmid types of 82 isolates were examined. the isolates were tested for the presence of 15-17- ... | 2008 | 18499361 |
| use of a chitosan-based hemostatic dressing in laparoscopic partial nephrectomy. | an external chitosan-based hemostatic bandage has been used to control aggressive bleeding from traumatic injuries. this study was to evaluate the feasibility of using an internal chitosan dressing based on the external platform to control hemorrhage and urinary leakage by sealing off the parenchymal wound following laparoscopic partial nephrectomy (lpn) in a porcine model. | 2008 | 17932955 |
| validation of two commercial real-time rt-pcr kits for rapid and specific diagnosis of classical swine fever virus. | two real-time rt-pcr kits, developed by lsi (taqvet csf) and adiagene (adiavet csf), obtained an agreement to be commercialised in france, subject to conditions, defined by the french classical swine fever (csf) national reference laboratory. the producers were asked to introduce an internal control to check the rna extraction efficacy. the different criteria assessed were sensitivity, "pestivirus specificity", reproducibility and ease of handling, using 189 different samples. these samples were ... | 2008 | 17913249 |
| a lightweight, partially absorbable mesh (ultrapro) for endoscopic hernia repair: experimental biocompatibility results obtained with a porcine model. | a meticulous surgical technique, a mesh of adequate dimensions, and use of a mesh with good biocompatibility properties are decisively important for minimizing the development of recurrences after endoscopic hernia repair surgery. mesh "shrinkage" is a function of the mesh's biocompatibility, that is, the properties of the mesh. large-pore, lightweight polypropylene meshes possess the best biocompatibility, and the newly developed meshes meet these requirements. | 2008 | 17963002 |
| indomethacin decreases optic nerve oxygen tension by a mechanism other than cyclo-oxygenase inhibition. | we investigated the effect of several non-steroidal anti-inflammatory drugs (nsaids), on the preoptic nerve oxygen tension (onpo2), as indomethacin previously has demonstrated a strong decreasing effect on onpo2. we tested whether these nsaids, like indomethacin, also reduce the increasing effect of dorzolamide on onpo2. | 2008 | 17965100 |
| signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity. | cytokines play a pivotal role in allergy development through activating signaling mechanisms, such as the janus kinase/signal transducer and activator of transcription (stat) pathway, which controls the expression of numerous proinflammatory genes. | 2008 | 17981315 |
| immunoglobulin light chain (igl) genes in zebrafish: genomic configurations and inversional rearrangements between (v(l)-j(l)-c(l)) gene clusters. | in mammals, immunoglobulin light chain (igl) are localized to two chromosomal regions (designated kappa and lambda). here we report a genome-wide survey of igl genes in the zebrafish revealing (v(l)-j(l)-c(l)) clusters spanning 5 separate chromosomes. to elucidate igl loci present in the zebrafish genome assembly (zv6), conventional sequence similarity searches and a novel scanning approach based on recombination signal sequence (rss) motifs were applied. rt-pcr with zebrafish cdna was used to c ... | 2008 | 18022691 |
| epidemiological study of hepatitis e virus infection in european wild boars (sus scrofa) in spain. | evidence of hepatitis e virus (hev) infection in spanish domestic pig has been reported and hence it was advisable to search for this zoonotic pathogen in wild boar populations. a total of 150 wild boar serum samples from eight geographic areas from south-central spain were used to investigate hev infection in european wild boar (sus scrofa) by means of serology and pcr and its distribution by age, region and management system. anti-hev igg, igm and iga were determined by an in-house elisa. the ... | 2008 | 18082340 |
| short-term effects of biocorrodible iron stents in porcine coronary arteries. | biocorrodible iron stents carry the potential to overcome limitations, such as chronic inflammation and premature recoil, posed by biodegradable polymer and magnesium alloy stents. this study aimed to test the safety and efficacy of biocorrodible iron stents in porcine coronary arteries. | 2008 | 18086136 |
| short- and long-term effects of a novel paclitaxel coated stent in the porcine coronary model. | drug eluting stents (des) are unique in allowing sustained release for weeks after a single short intervention. the challenge with des still remaining is the combination of a biocompatible drug-eluting matrix including an antiproliferative drug showing efficacy and safety in restenosis prevention. the aim of the present animal studies was to evaluate the novel paclitaxel coated coroflex. please stent in the porcine coronary model. | 2008 | 18087665 |
| electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. | newer guidelines address the importance of effective chest compressions, citing evidence that this primary intervention is usually suboptimally performed during cardiopulmonary resuscitation. we therefore sought a readily available option for monitoring the effectiveness of chest compressions, specifically using the electrocardiogram. | 2008 | 18090357 |
| postresuscitation myocardial diastolic dysfunction following prolonged ventricular fibrillation and cardiopulmonary resuscitation. | postresuscitation myocardial dysfunction is one of the leading causes of early death after successful resuscitation from sudden death. however, the diastolic characteristics of postresuscitation myocardial dysfunction are not well defined. we therefore investigated the postresuscitation left ventricular diastolic function following prolonged cardiac arrest and subsequent cardiopulmonary resuscitation. | 2008 | 18090365 |
| effects of ventilation with 100% oxygen during early hyperdynamic porcine fecal peritonitis. | early goal-directed therapy aims at balancing tissue oxygen delivery and demand. hyperoxia (i.e., pure oxygen breathing) has not been studied in this context, since sepsis increases oxygen radical production, which is believed to be directly related to the oxygen tension. on the other hand, oxygen breathing improved survival in various shock models. therefore, we hypothesized that hyperoxia may be beneficial during early septic shock. | 2008 | 18091553 |
| a new device to simplify flexible endoscopic treatment of zenker's diverticulum. | endoscopic treatment of a zenker's diverticulum (zd) is challenged by maintaining a stable position and visual field. an oblique transparent cap and an overtube have been used with success. the porcine hypopharyngeal pouch is similar to a zd. while using the widespread emr device (wemr) in the esophagus, we realized that the design may be advantageous for treatment of a zd. | 2008 | 18155432 |