Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| fatty acids in tea shoots (camellia sinensis (l.) o. kuntze) and their effects on the growth of retinal rf/6a endothelial cell lines. | chemo-protective effects of tea on ocular diseases were recorded in chinese pharmacopoeia about 2000 years ago by eating tea. in the present study, contents of fatty acids (fas) in tea shoots were determined by capillary gc; and the growth of rf/6a cells was also investigated by exposure to various representative fas existing in tea shoots with pathologically relevant concentrations (40-500 microm) by ameliorated mtt assay and flow cytometry. electron spin resonance (esr) was used to measure oxy ... | 2007 | 17262883 |
| effect of nitrogen form and root-zone ph on growth and nitrogen uptake of tea (camellia sinensis) plants. | tea (camellia sinensis) is considered to be acid tolerant and prefers ammonium nutrition, but the interaction between root zone acidity and n form is not properly understood. the present study was performed to characterize their interaction with respect to growth and mineral nutrition. | 2007 | 17204540 |
| interactions between smoking and other exposures associated with lung cancer risk in women: diet and physical activity. | the objective of the study is to estimate the differences in the impact of diet and physical exercise on lung cancer risk in female nonsmokers vs. smokers, and reveal interactions, if any. in a hospital based case-control study, data collected by in-person interviews from 569 female lung cancer cases and 2120 controls were analyzed using unconditional logistic regression stratifying by appropriate factors. protective effects were observed for intake of milk/dairy products (or=0.57, 95%ci 0.35-0. ... | 2007 | 17203897 |
| bioactive saponins and glycosides. xxv. acylated oleanane-type triterpene saponins from the seeds of tea plant (camellia sinensis). | seven new acylated oleanane-type triterpene oligoglycosides, theasaponins a(4) (1), a(5) (2), c(1) (3), e(8) (4), e(9) (5), g(1) (6), and h(1) (7), were isolated from the seeds of japanese tea plant (camellia sinensis). the structures of 1-7 were elucidated on the basis of chemical and physicochemical evidence. | 2007 | 17202702 |
| protective effect of black tea polyphenols against 7,12-dimethylbenz[a]anthracene-induced genotoxicity and oxidative stress during hamster buccal pouch carcinogenesis. | abstract this study was designed to evaluate the protective effect of black tea polyphenols (polyphenon b) against genotoxicity and oxidative stress during 7,12-dimethylbenz[a]anthracene (dmba)-induced hamster buccal pouch (hbp) carcinogenesis. since the bone marrow reflects hematopoietic stress caused by tumor cells, we used the frequency of micronuclei, the extent of lipid peroxidation, and the status of antioxidants in the bone marrow plasma as intermediate biomarkers of oxidative stress. all ... | 2007 | 20020977 |
| evaluation of black tea gel and its protection potential against uv. | in this study, aqueous and alcoholic extracts of black tea were obtained. the black tea extracts were tested in vitro for their ultraviolet (uv) absorption profile. it was found that both extracts showed uv absorption and followed the same path based on the wavelength. aqueous extract showed a stronger absorptivity per weight basis than the alcoholic extract of black tea. a peak was obtained between 250 and 300 nm. after 300 nm, uv absorption decreased fast towards 400 nm with a low absorptivity ... | 2007 | 18489382 |
| structures of epicatechin gallate trimer and tetramer produced by enzymatic oxidation. | during black tea production, catechins and their galloyl esters are enzymatically oxidized to generate a complex mixture of black tea polyphenols. the role of galloyl ester groups in this process has yet to be determined. enzymatic oxidation of epicatechin 3-o-gallate (1) yielded two new oxidation products, theaflavate c and bistheaflavate a, along with theaflavate a (2), a known dimer of 1 generated by coupling of the b-ring with the galloyl group. theaflavate c is a trimer of 1 and possesses t ... | 2007 | 18057757 |
| the effects of tea on psychophysiological stress responsivity and post-stress recovery: a randomised double-blind trial. | tea has anecdotally been associated with stress relief, but this has seldom been tested scientifically. | 2007 | 17013636 |
| assessment of the polyphenolic composition of the organic extracts of mauritian black teas: a potential contributor to their antioxidant functions. | there is increasing interest in the emerging view that tea improves the antioxidant status in vivo and thereby helps to lower risk of certain types of cancer, coronary heart disease and stroke and its component biofactors could provide prophylactic potential for these diseases. the polyphenolic composition and the antioxidant properties of organic extracts (acetone/methanol) of mauritian commercial black teas were evaluated. hplc data of the individual compounds revealed remarkably high levels ( ... | 2006 | 17012766 |
| copper(ii)-selective fluorimetric bulk optode membrane based on a 1-hydroxy-9,10-anthraquinone derivative having two propenyl arms as a neutral fluorogenic ionophore. | a new optical chemical sensor has been developed for the selective determination of copper(ii) ions in aqueous solutions. the reversible sensing system was prepared by incorporating 1-hydroxy-2-(prop-2'-enyl)-4-(prop-2'-enyloxy)-9,10-anthraquinone (aq) as a neutral cu2+-selective fluoroionophore in the plasticized pvc membrane with potassium tetrakis(p-chlorophenyl borate) as an anionic additive. the response of the sensor is based on the fluorescence quenching of aq by cu2+ ions. at a ph 5.5, t ... | 2006 | 16344241 |
| green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies. | experimental studies have shown that tea and tea polyphenols have anti-carcinogenic properties against breast cancer. a number of epidemiologic studies, both case-control and cohort in design, have examined the possible association between tea intake and breast cancer development in humans. this meta-analysis included 13 papers which examined populations in eight countries and provided data on consumption of either green tea or black tea, or both in relation to breast cancer risk. summary odds r ... | 2006 | 16311246 |
| copper(ii)-selective fluorimetric bulk optode membrane based on a 1-hydroxy-9,10-anthraquinone derivative having two propenyl arms as a neutral fluorogenic ionophore. | a new optical chemical sensor has been developed for the selective determination of copper(ii) ions in aqueous solutions. the reversible sensing system was prepared by incorporating 1-hydrpxy-2-(prop-2'-enyl)-4-(prop-2'-enyloxy)-9,10-anthraquinone (aq) as a neutral cu2+-selective fluoroionophore in the plasticized pvc membrane with potassium tetrakis(p-chlorophenyl borate) as an anionic additive. the response of the sensor is based on the fluorescence quenching of aq by cu2+ ions. at a ph 5.5, t ... | 2006 | 16307904 |
| more tea for septic patients?--green tea may reduce endotoxin-induced release of high mobility group box 1 and other pro-inflammatory cytokines. | despite recent advances in antibiotic therapy and intensive care, sepsis remains widespread problems in critically ill patients. the high mortality of sepsis is in part mediated by bacterial endotoxin, which stimulates macrophages/monocytes to sequentially release early (e.g., tnf, il-1, and ifn-gamma) and late (e.g., hmgb1) pro-inflammatory cytokines. in light of our recent discovery of hmgb1 as a late mediator of lethal systemic inflammation, and the observation that green tea (camellia sinens ... | 2006 | 16266789 |
| characterization of the key aroma compounds in the beverage prepared from darjeeling black tea: quantitative differences between tea leaves and infusion. | by application of the aroma extract dilution analysis on the volatile fraction isolated from a black tea infusion (darjeeling gold selection), vanillin (vanilla-like), 4-hydroxy-2,5-dimethyl-3(2h)-furanone (caramel), 2-phenylethanol (flowery), and (e,e,z)-2,4,6-nonatrienal (oat-flake-like) were identified with the highest flavor dilution (fd) factors among the 24 odor-active compounds detected in the fd factor range of 4-128. quantitative measurements performed by means of stable isotope dilutio ... | 2006 | 16448203 |
| stimulated parametric emission microscopy. | we propose a novel microscopy technique based on the four-wave mixing (fwm) process that is enhanced by two-photon electronic resonance induced by a pump pulse along with stimulated emission induced by a dump pulse. a ti:sapphire laser and an optical parametric oscillator are used as light sources for the pump and dump pulses, respectively. we demonstrate that our proposed fwm technique can be used to obtain a one-dimensional image of ethanol-thinned coumarin 120 solution sandwiched between a ho ... | 2006 | 19503398 |
| the role of tea and tea flavonoids in cardiovascular health. | consumption of green or black tea has been inversely associated with the development and progression of cardiovascular diseases. in this review, the current knowledge about protective effects of tea and tea constituents, particularly flavonoids, on the cardiovascular system is summarized. underlying mechanisms for the beneficial effects of tea include vasculoprotective, antioxidative, antithrombogenic, anti-inflammatory, and lipid-lowering properties of tea flavonoids. although promising experim ... | 2006 | 16404706 |
| catechin transformation as influenced by aluminum. | polyphenols (catechins) are vital biomolecules in tea plants (camellia sinensis), which are well-known as typical al accumulators. however, the interaction between al and catechin remains obscured. the objective of the present study was to investigate the effect of al on the transformation of (+)-catechin. solutions with oh/al molar ratios of 2.5 (ph 5.5) and 3.0 (ph 7.0) prepared at al/catechin molar ratios (r) of 0, 0.2, 0.4, 0.6, 0.8, and 1.0 were aged for 7 and 30 days, respectively. the pre ... | 2006 | 16390201 |
| hepatotoxicity associated with supplements containing chinese green tea (camellia sinensis). | 2006 | 16389263 | |
| consumption of coffee, but not black tea, is associated with decreased risk of premenopausal breast cancer. | caffeine has been suggested as a possible risk factor for breast cancer, potentially through its effect of facilitating the development of benign breast disease. however, coffee and tea also contain polyphenols, which exhibit anticarcinogenic properties. a hospital-based, case-control study was conducted to evaluate the role of coffee, decaffeinated coffee, and black tea in breast cancer etiology. study participants included 1932 cases with primary, incident breast cancer and 1895 hospital contr ... | 2006 | 16365077 |
| genetic integrity of somaclonal variants in tea (camellia sinensis (l.) o kuntze) as revealed by inter simple sequence repeats. | adoption of inter simple sequence repeats (issr) technique to analyze the genetic variability of somatic embryo derived tea plants was evaluated. morphological characterisation of the field grown plants revealed no identical character aligning with the parent, upasi-10. out of 40 primers, 15 exhibited concurrent polymorphism were selected for the study. genetic variability of somaclones derived from single line cotyledonary culture ranged from 33.0 to 55.0%. a unique fragment of 1.2kb was visibl ... | 2006 | 16360228 |
| tealeaves may release or absorb fluoride, depending on the fluoride content of water. | as the tea plant (camellia sinensis) is known to accumulate fluoride from the soil, the tealeaves may contain high concentrations of fluoride, which is easily released during infusion. in this study, we have tested the possible effect of original fluoride concentration in the water on the fluoride release from tea. moreover, we wanted to test the possible capacity of tealeaves (commercially available tea) to absorb fluoride from high-fluoride water. in low-fluoride water, fluoride is easily rele ... | 2006 | 16356534 |
| theaflavin-3, 3'-digallate induces epidermal growth factor receptor downregulation. | black tea is one of the most popular beverages worldwide and especially in western nations. theaflavins, a mixture of theaflavin (tf-1), theaflavin-3-gallate (tf-2a), theaflavin-3'-gallate (tf-2b), and theaflavin-3,3'-digallate (tf-3) are the major components of black tea. among these black tea components, theaflavin is generally considered to be the more effective component for the inhibition of carcinogenesis. recently, tf-3 has been shown to have an antiproliferative effect on tumor cells, bu ... | 2006 | 16353237 |
| analytical separation of tea catechins and food-related polyphenols by high-speed counter-current chromatography. | high-speed counter-current chromatography (hsccc) using the type-j coil planet centrifuge was applied to compositional analysis of tea catechins and separation of other food-related polyphenols. the hsccc separation of nine different standard compounds and those from extracts of commercial tea leaves was performed with a two-phase solvent system composed of tert-butyl methyl ether-acetonitrile-0.1% aqueous trifluoroacetic acid (tfa) (2:2:3, v/v/v) by eluting the upper organic phase at a flow rat ... | 2006 | 16239007 |
| green tea leaf extract improves lipid and glucose homeostasis in a fructose-fed insulin-resistant hamster model. | the present study evaluated the effect of green tea (camellia sinensis l.) leaf extract on triglyceride and glucose homeostasis in a fructose-fed hypertriglyceridemic, insulin-resistant hamster model. there was a significant decrease in plasma triglyceride levels following supplementation of the green tea epigallocatechin gallate-enriched extract (42% at 150 mg/(kg day) to 62% at 300 mg/(kg day) for 4 weeks). compared to baseline, the fructose control group at the end of the study showed elevate ... | 2006 | 16202550 |
| influence of tea drinking on manganese intake, manganese status and leucocyte expression of mnsod and cytosolic aminopeptidase p. | since black tea contains high levels of manganese (mn), we investigated the relationship between dietary mn intake, circulating mn levels and leucocyte expression of two mn-dependent enzymes in tea drinkers and non-tea drinkers. | 2006 | 16118651 |
| all teas are not created equal: the chinese green tea and cardiovascular health. | tea is one of the most widely consumed beverages in the world, next only to water. it can be categorized into three types, depending on the level of fermentation, i.e., green (unfermented), oolong (partially fermented) and black (fermented) tea. in general, green tea has been found to be superior to black tea in terms of antioxidant activity owing to the higher content of (-)-epigallocatechin gallate. the processes used in the manufacture of black tea are known to decrease levels of the monometr ... | 2006 | 15978686 |
| novel inhibitors of fatty-acid synthase from green tea (camellia sinensis xihu longjing) with high activity and a new reacting site. | recent studies have shown that fas (fatty acid synthase) is a potential therapeutic target of obesity. in the present paper we report that extract of green tea (camellia sinensis xihu longjing) inhibits fas effectively with an ic50 value of 12.2 microg dry weight/ml. the ability of gte (green tea extract) to inhibit fas is more potent than that of two known inhibitors in green tea leaves, egcg (epigallocatechin gallate) and ecg (epicatechin gallate). we find that (-)-cg (catechin gallate) is a v ... | 2006 | 15943584 |
| age-related variations in flavonoid intake and sources in the australian population. | to estimate flavonoid intake in the australian population. | 2006 | 17125569 |
| black tea polyphenols protect against 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. | dietary chemoprevention has emerged as a cost-effective approach for cancer control. we evaluated the chemopreventive effects of black tea polyphenols (polyphenon-b) administration during the preinitiation phase of 7,12-dimethylbenz[a]anthracene (dmba)-induced hamster buccal pouch (hbp) carcinogenesis. the expression of proliferating cell nuclear antigen (pcna) in the buccal pouch and the concentration of lipid peroxides, protein carbonyl, and the antioxidant status in the buccal pouch, liver an ... | 2006 | 17120615 |
| flow injection potentiometric determination of total antioxidant activity of plant extracts. | a new flow injection potentiometric (fip) method, rapid, reproducible and simple to apply, has been developed for the in vitro evaluation of antioxidative capacity of aqueous plant extracts. this method is based on the transient negative signal measurements with a flow-type platinum electrode detector due to the composition change of a [fe(cn)6]3-/[fe(cn)6]4- redox-reagent solution. the variables affecting the signal height such as composition and concentration of redox-reagent, injected sample ... | 2006 | 17723555 |
| isotheasaponins b1-b3 from camellia sinensis var. sinensis tea leaves. | three saponins, isotheasaponins b1-b3, were isolated from the leaves of the tea plant camellia sinensis var. sinensis, and their structures were determined to be theasapogenol b [beta-d-galactopyranosyl(1-->2)][beta-d-xylopyranosyl(1-->2)-alpha-l-arabinopyranosyl(1-->3)]-beta-d-gulcopyranosiduronic acid with two acyl groups by spectroscopic analysis. | 2006 | 16808937 |
| hepatotoxicity due to extracts of chinese green tea (camellia sinensis): a growing concern. | 2006 | 16793166 | |
| characterization of epoxydecenal isomers as potent odorants in black tea (dimbula) infusion. | in a black tea (dimbula) infusion, the potent "sweet and/or juicy" odorants were identified as the cis- and trans-4,5-epoxy-(e)-2-decenals by comparison of their gas chromatography retention indices, mass spectra, and odor quality to those of the actual synthetic compounds. of the two odorants, cis-4,5-epoxy-(e)-2-decenal has been identified for the first time in the black tea. on the basis of the aroma extract dilution analysis on the flavor distillate obtained using the solvent-assisted flavor ... | 2006 | 16787030 |
| nutritional risk factors for the development of chronic obstructive pulmonary disease (copd) in male smokers. | the aim of this study was to investigate whether nutritional risk factors, especially black tea consumptions, are inversely associated with the development of chronic obstructive pulmonary disease (copd) in male smokers. | 2006 | 16782241 |
| acute effect of black and green tea on aortic stiffness and wave reflections. | while most studies have shown an inverse relation between tea consumption and cardiovascular risk, other studies have shown opposite results. aortic stiffness and wave reflections are markers of cardiovascular disease and prognosticators of cardiovascular risk. | 2006 | 16766780 |
| metabolite profiling and characterization of somaclonal variants in tea (camellia spp.) for identifying productive and quality accession. | a study has been undertaken to characterize 15 field grown somaclonal variants derived from cotyledonary tissues of upasi-10 using morphological, physiological and biochemical characters. although variants were derived from upasi-10, a very few variants possessed unique "chinery" characters while others exhibited "assam" characters. however, no variant showed identical morphological characters aligning with the parent. somaclonal variants showed distinct variation in terms of photosynthetic carb ... | 2006 | 16714038 |
| selected diet and lifestyle factors are associated with estrogen metabolites in a multiracial/ethnic population of women. | diet and lifestyle factors, body size, and smoking behavior may influence estrogen metabolism, but the nature of these relations may vary according to race/ethnic groups. we evaluated the association of lifestyle factors with estrogen metabolites 2-hydroxyestrone (2-ohe1) and 16alpha-hydroxyestrone (16alpha-ohe1) in a racially diverse population. with a cross-sectional study design, urine samples from 1881 african-american, caucasian, chinese, japanese, and hispanic women, aged 42-52 y, from the ... | 2006 | 16702326 |
| modulation of aromatase activity by diet polyphenolic compounds. | estrogens are involved in physiological actions related to reproduction, body fat distribution, and maintenance of bone mass and are also related to the pathogenesis of estrogen-dependent cancers. the aim of this work was to study the effect of polyphenols on estrogen synthesis. the effect of polyphenols and polyphenolic-rich beverages on aromatase activity was tested in jar cells (a choriocarcinoma cell line) through the tritiated water release assay. some of the tested polyphenols inhibited es ... | 2006 | 19127721 |
| the effect of green tea in oxidative stress. | green tea, an infusion prepared with the leaves of camellia sinensis is particularly rich in flavonoids, which are strong antioxidants. tea drinking, by providing antioxidants, may become valuable in several oxidative stress conditions. our aim was to evaluate the effect of green tea drinking on some factors reflecting the development of oxidative stress in plasma and in erythrocytes. | 2006 | 16698148 |
| black tea extract and its major polyphenolic pigment may ameliorate the gastrointestinal disorder in irritable bowel syndrome. | 2006 | 16678978 | |
| high tea consumption diminishes salivary 17beta-estradiol concentration in polish women. | we hypothesized that among reproductive-age women consuming large quantities of tea, the production of estradiol would be suppressed. it has been shown that catechins and theaflavines, the major constituents of tea, inhibit aromatase, an enzyme which catalyses the conversion of androgens to oestrogens. our study included polish women living in urban (n 61) and rural (n 48) areas. women collected daily saliva samples for one complete menstrual cycle and filled out dietary questionnaires. saliva s ... | 2006 | 16611391 |
| potent inhibitory effects of black tea theaflavins on off-odor formation from citral. | the present study was conducted to investigate the ability of black tea theaflavins to inhibit the off-odor formation from citral under acidic aqueous conditions. acidic buffer solutions (ph 3.0) containing citral (10 mg/l) and an inhibitor (0-5 mg/l) were stored at 40 degrees c for 2 weeks. the formation of possible off-odorants p-cresol and p-methylacetophenone in the citral solutions was monitored by high-performance liquid chromatography. a mixture of the theaflavins showed inhibitory effect ... | 2006 | 16608230 |
| induction of neutral endopeptidase (nep) activity of sk-n-sh cells by natural compounds from green tea. | deposition of amyloid beta-peptide as senile plaques in the brain is one of the neuropathological hallmarks of alzheimer's disease, which is the most prevalent progressive neurodegenerative disease leading to dementia. neutral endopeptidase is one of the major beta-amyloid-degrading enzymes in the brain. to examine the influence of different polyphenols and other natural products from green tea extract (from camellia sinensis, theaceae), we used the neuroblastoma cell line sk-n-sh and studied th ... | 2006 | 16597367 |
| metabolic effects of spices, teas, and caffeine. | consumption of spiced foods or herbal drinks leads to greater thermogenesis and in some cases to greater satiety. in this regard, capsaicin, black pepper, ginger, mixed spices, green tea, black tea and caffeine are relevant examples. these functional ingredients have the potential to produce significant effects on metabolic targets such as satiety, thermogenesis, and fat oxidation. a significant clinical outcome sometimes may appear straightforwardly but also depends too strongly on full complia ... | 2006 | 16580033 |
| preconcentration system for cadmium and lead determination in environmental samples using polyurethane foam/me-btanc. | in this work, polyurethane foam (puf) loaded with 2-(6'-methyl-2'-benzothiazolylazo)chromotropic acid (me-btanc) was packed in a minicolumn and it was used in an on-line preconcentration system for cadmium and lead determination. optimum hydrodynamic and chemical conditions for metal sorption were investigated. the effects of several foreign substances on the adsorption of cadmium and lead were also reported. the enrichment factor obtained was 37 (cd and pb) for 180 s preconcentration time. the ... | 2006 | 16530947 |
| fluoride levels in various black tea commodities: measurement and safety evaluation. | in order to determine the fluoride content of various products of black tea and to make safety evaluations, 37 commodities in the different manufactured forms of tea were assessed by means of ion-selective electrode and spectrophotometric methods. the results showed wide differences in fluoride levels. the fluoride content was found 0.95-1.41 mg/l in black tea sticks, 0.70-2.44 mg/l in black tea granules and 1.15-6.01 mg/l in black tea bags. of the products tested, the fluoride content was great ... | 2006 | 16510229 |
| effects of tea polyphenols on emulsification of olive oil in a small intestine model system. | tea catechins have been shown to reduce plasma cholesterol and suppress hypertriacylglycerolemia by reducing triglyceride absorption. however, the mechanism is not yet clear. one of the possible mechanisms is that tea polyphenols may modify dietary fat emulsification in the gastrointestinal tract. the digestive enzyme (lipase) acts on specific emulsion interface properties (droplet size and surface area). therefore, changes in these properties may modify emulsification and lead to changes in die ... | 2006 | 16506852 |
| 5s rdna gene diversity in tea (camellia sinensis (l.) o. kuntze) and its use for variety identification. | variability in the organization of repeats of 5s rdna is useful for phylogenetic studies in various crops. we found variable repeats of 5s rdna gene in the genome of tea (camellia sinensis (l.) o. kuntze) during southern hybridization. variability in the repeats of 5s rdna with specific restriction endonucleases (sau3ai, bamhi, and apoi) was analyzed in 28 different tea clones representing 3 types of tea. our results clearly show that the 5s rdna gene in tea could be used as a molecular marker t ... | 2006 | 16462906 |
| enhancement of erythrocyte antioxidants by green and black tea polyphenols during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. | we evaluated the comparative chemopreventive efficacy of green tea polyphenols (polyphenon-e) and black tea polyphenols (polyphenon-b) on 7,12-dimethylbenz[a]anthracene (dmba)-induced hamster buccal pouch (hbp) carcinogenesis. lipid peroxidation, reduced and oxidized glutathione (gsh and gssg, respectively), and the gsh-dependent enzymes glutathione peroxidase and glutathione s-transferase in the erythrocytes were used as biomarkers of chemoprevention. enhanced lipid peroxidation in erythrocytes ... | 2006 | 17004901 |
| high-throughput analysis of catechins and theaflavins by high performance liquid chromatography with diode array detection. | increased interest in potential health-protective activities of flavonoid-rich tea has created the need to take advantage of hplc column and system advances in order to optimize methodologies for flavonoid analysis. two new rp-c18 methods for hplc-dad analysis of tea flavonoids were developed to facilitate separation of catechins within 5 min and separation of catechins and theaflavins within 10 min total analysis time. calibration results indicate that these methods have on-column limits of det ... | 2006 | 16919286 |
| adsorption of chlorhexidine and black tea onto in vitro salivary pellicles, as studied by ellipsometry. | the adsorption from 0.2% (w/w) chlorhexidine and black tea solutions onto an in vitro pellicle from whole unstimulated saliva on hydroxyapatite discs was studied by ellipsometry. it was found that chlorhexidine adsorbed to the pellicle and caused a modification of the pellicle properties, leading to a subsequent increase in adsorption of salivary and black tea components. there was a distinct order-of-addition effect, whereby chlorhexidine followed by black tea gave an overall greater adsorption ... | 2006 | 16911105 |
| [damage to and protection of sperm dna]. | the damage to sperm dna is one of the most important causes of male infertility. some sperm with damaged dna may escape from the sperm surveillance mechanism and transmit the damage to the offspring. so research on the damage to sperm dna has become one of the hot spots in reproductive medicine. the factors that would damage sperm dna include oxidative stress, microelements, reproductive toxic substances, radioactive rays, and so on, while the body depends on the compressed sperm dna and anti-ox ... | 2006 | 16894946 |
| epigallocatechin-3-gallate (egcg): chemical and biomedical perspectives. | the compound (-)-epigallocatechin-3-gallate (egcg) is the major catechin found in green tea [camellia sinensis l. ktze. (theaceae)]. this polyphenolic compound and several related catechins are believed to be responsible for the health benefits associated with the consumption of green tea. the potential health benefits ascribed to green tea and egcg include antioxidant effects, cancer chemoprevention, improving cardiovascular health, enhancing weight loss, protecting the skin from the damage cau ... | 2006 | 16876833 |
| mechanisms of cancer prevention by green and black tea polyphenols. | drinking green tea is associated with decreased frequency of cancer development. this review outlines the wide range of mechanisms by which epigallocatechin gallate (ecgc) and other green and black tea polyphenols inhibit cancer cell survival. egcg suppressed androgen receptor expression and signalling via several growth factor receptors. cell cycle arrest or apoptosis involved caspase activation and altered bcl-2 family member expression. egcg inhibited telomerase activity and led to telomere f ... | 2006 | 17017850 |
| trapping reactions of reactive carbonyl species with tea polyphenols in simulated physiological conditions. | the carbonyl stress that leads to the formation of advanced glycation end products (ages) in diabetes mellitus has drawn much attention recently. reactive alpha-dicarbonyl compounds, such as glyoxal (go) and methylglyoxal (mgo), have been shown to be a high potential glycation agent in vitro and in vivo. in this study, epicatechins in green tea and theaflavins in black tea were found to be able to reduce the concentration of mgo in physiological phosphate buffer conditions. modified mgo derivati ... | 2006 | 17103374 |
| [effect of plant biocomposites based on georgian tea "per se" and in combination with cisplatin on walker carcinosarcoma w-256 and guerin's carcinoma growth rate in rats]. | green tea biocomposite had effectivey hampered the growth of rat walker w-256 carcinoma and in less extent rat guerin's carcinoma. black tea biocomposite had not practically influenced on guerin's carcinoma growth. the biocomposite from green tea and extract from red vine rind and lemon suppressed at the level of tendency the growth of rat walker w-256 carcinoma. the biocomposite from green tea and extract from red vine rind had hampered only guerin's carcinoma growth and at the tendency had inc ... | 2006 | 17427433 |
| black tea polyphenols restrict benzopyrene-induced mouse lung cancer progression through inhibition of cox-2 and induction of caspase-3 expression. | lung cancer is one of the leading causes of cancer related death in most developed and many developing countries of the world. due to lack of validated screening methods and poor prognosis, treatment of lung cancer has not improved significantly over the last two decades. therefore the risk of the disease needs to be minimized by preventive measures. one approach for lung cancer prevention envisages reversal or restriction of precancerous lesions by chemopreventive intervention. it demands a dee ... | 2006 | 17250449 |
| theaflavin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-inflammatory effect and modulation of stat-1. | theaflavin, a major constituent of black tea, possesses biological functions such as the antioxidative, antiviral, and anti-inflammatory ones. the purpose of this study was to verify whether theaflavin reduces focal cerebral ischemia injury in a rat model of middle cerebral artery occlusion (mcao). male sprague-dawley rats were anesthetized and subjected to 2 hours of mcao followed 24 hours reperfusion. theaflavin administration (5, 10, and 20 mg/kg, i.v.) ameliorated infarct and edema volume. t ... | 2006 | 17392572 |
| black tea ameliorates aflatoxin-induced lipid peroxidation in the kidney of mice. | oral administration of 25 and 50 mg of aflatoxin in 0.2 ml olive oil/animal/day for 30 days caused dose-dependent and significantly higher lipid peroxidation in the kidney of aflatoxin-treated mice than in the controls. the levels of non-enzymatic antioxidant such as glutathione as well as the enzymatic antioxidants such as superoxide dismutase, glutathione peroxidase and catalase were significantly lower in the kidney of aflatoxin-treated mice than in the controls. black tea extract (2%) treatm ... | 2006 | 17203869 |
| green tea [camellia sinensis (l.) o. kuntze] extract reverses the despair behaviour in reserpinised and diabetic mice. | green tea (c. sinensis) extract (gte) dose dependently produced reversal of despair in normal, reserpinised and diabetic mice, thereby demonstrating an antidepressant effect. although the exact mechanism is yet to be explored, the possible inhibition of catechol-o-methyl transferase and monoamine oxidase enzymes may be responsible for antidepressant activity of gte. | 2006 | 17205714 |
| inhibition of pathogenic bacterial adhesion by acidic polysaccharide from green tea (camellia sinensis). | an acidic polysaccharide cs-f2 from camellia sinensis was examined to characterize its anti-adhesive effects against pathogenic bacteria, most notably helicobacter pylori, propionibacterium acnes, and staphylococcus aureus. cs-f2 showed marked inhibitory activity against the pathogen-mediated hemagglutination with a minimum inhibitory concentration (mic) between 0.01 and 0.1 mg/ml, which is lower than the previously reported mic values for panax ginseng and artemisia capillaris. the inhibitory e ... | 2006 | 17090112 |
| availability of weight-loss supplements: results of an audit of retail outlets in a southeastern city. | the sale of nonprescription weight-loss products accounts for millions of dollars spent by americans trying to lose weight, yet there is little evidence for effectiveness and there are multiple safety concerns. the purpose of this study was to determine what products, and ingredients within products, were available at retail outlets in a metropolitan area. a purposive sampling strategy identified 73 retail outlets. an audit form was used to collect information from product labels. the audit iden ... | 2006 | 17126636 |
| reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols. | the immunosuppressants ciclosporin (cyclosporin a, csa) and tacrolimus can cause severe nephrotoxicity. since csa increases free radical formation, this study investigated whether an extract from camellia sinensis, which contains several polyphenolic free radical scavengers, could prevent nephrotoxicity caused by csa and tacrolimus. rats were fed powdered diet containing polyphenolic extract (0-0.1%) starting 3 days before csa or tacrolimus. free radicals were trapped with alpha-(4-pyridyl-1-oxi ... | 2006 | 17132217 |
| the cupric ion reducing antioxidant capacity and polyphenolic content of some herbal teas. | the total antioxidant capacity of the aqueous extracts of some endemic herbs-prepared as infusions by steeping these herbs in hot water--was assayed with bis(neocuproine)copper(ii) chloride, also known as the cupric ion reducing antioxidant capacity (cuprac) reagent, which was easily accessible, rapid, stable and responsive to both hydrophilic and lipophilic antioxidants. the highest antioxidant capacities of some herbal teas available in the turkish market were observed for scarlet pimpernel (a ... | 2006 | 17135020 |
| the effects of tea extracts on proinflammatory signaling. | skin toxicity is a common side effect of radiotherapy for solid tumors. its management can cause treatment gaps and thus can impair cancer treatment. at present, in many countries no standard recommendation for treatment of skin during radiotherapy exists. in this study, we explored the effect of topically-applied tea extracts on the duration of radiation-induced skin toxicity. we investigated the underlying molecular mechanisms and compared effects of tea extracts with the effects of epigalloca ... | 2006 | 17140430 |
| protective effect of black and green tea against carbon tetrachloride-induced oxidative stress in rats. | to assess the effects of green and black tea on carbon tetrachloride (ccl4)-induced oxidative stress in rats. | 2006 | 17143353 |
| efficacy of 12 weeks supplementation of a botanical extract-based weight loss formula on body weight, body composition and blood chemistry in healthy, overweight subjects--a randomised double-blind placebo-controlled clinical trial. | the aim of this study was to evaluate the efficacy and safety of composite extracts in reducing weight, as the main outcome measure. secondary measures of the study were body composition change. | 2006 | 17052970 |
| arsenic removal from groundwater by pretreated waste tea fungal biomass. | arsenic contamination in ground water poses a serious threat on human health. the tea fungus, a waste produced during black tea fermentation has been examined for its capacity to sequester the metal ions from ground water samples. autoclaved tea fungal mat and autoclaving followed by fecl3 pretreated tea fungal mat were exploited for removal of as(iii), as(v) and fe(ii) from ground water sample collected from kolkata, west bengal, india. the biosorption rate tends to increase with the increase i ... | 2006 | 16216732 |
| determination of minerals extracted from several commercial teas (camellia sinensis) to hot water (infusion). | mineral contents of some tea and their infusions drunk in turkey were established by inductively coupled plasma atomic emission spectrometry. the al, ca, k, mg, mn, p, and s contents were very high in both infusions and tea (i.e., pieces of the tea plant). the as, cd, cr, li, pb, and se contents of infusion and tea were found to be very low. the level of k of all samples is higher than those of other minerals. generally, mineral contents of tea were found to be higher than those of tea infusions ... | 2006 | 16579740 |
| beneficial effects of green tea--a review. | tea is the most consumed drink in the world after water. green tea is a 'non-fermented' tea, and contains more catechins, than black tea or oolong tea. catechins are in vitro and in vivo strong antioxidants. in addition, its content of certain minerals and vitamins increases the antioxidant potential of this type of tea. since ancient times, green tea has been considered by the traditional chinese medicine as a healthful beverage. recent human studies suggest that green tea may contribute to a r ... | 2006 | 16582024 |
| aqueous extract of black tea (camellia sinensis) prevents ethanol+cholecystokinin-induced pancreatitis in a rat model. | black tea extract (bte), a phytocompound has been attributed with a plethora of health-promoting actions. we have previously demonstrated that bte inhibits chronic hepatitis in a rat model induced with high-fat and ethanol (etoh). this study reports that bte prevents altered pancreatic acinar cell functions, oxidative stress, inflammatory changes and dna damage in the etoh+cholecystokinin (cck)-induced model of pancreatitis. the etoh+cck model rats were administered with bte, and were examined t ... | 2006 | 16289561 |
| in vitro cytotoxicity of a theaflavin mixture from black tea to malignant, immortalized, and normal cells from the human oral cavity. | the growth inhibitory effects of a theaflavin mixture from black tea were more pronounced to malignant (cal27; hsc-2; hsg1) and immortalized (s-g; gt1) cells than to normal (hgf-2) cells from the human oral cavity. studies with malignant carcinoma cal27 cells and immortalized gt1 fibroblasts showed that cytotoxicity of the theaflavin mixture was enhanced as the exposure time was increased, with the tumor cal27 cells more sensitive than the gt1 cells. hydrogen peroxide (h(2)o(2)) was detected in ... | 2006 | 16297594 |
| anticlastogenic effects of black tea polyphenols theaflavins and thearubigins in human lymphocytes in vitro. | black tea accounts for nearly 80% of total world tea production. it contains dimeric flavanols and polymeric polyphenols known as theaflavins (tf) and thearubigins (tr). tr is exclusively present in black tea. on the basis of our previous potent antimutagenic and anticlastogenic effects of tf and tr in vitro in bacterial system and in vivo in mouse bone marrow cells, we have decided to extend our study in human cells in vitro. this study investigated the anticlastogenic effects of black tea poly ... | 2006 | 16314069 |
| safety studies on epigallocatechin gallate (egcg) preparations. part 1: genotoxicity. | public interest in green tea has grown recently due to the potential health benefits from its consumption. epigallocatechin gallate (egcg), a principal polyphenolic component of green tea, is considered key to these healthful qualities. although numerous studies have evaluated the anti-cancer effects of green tea and egcg, few have examined the safety of egcg consumption. the genotoxic potential of a concentrated egcg preparation was tested in salmonella and l5178y tk+/- mouse lymphoma cell assa ... | 2006 | 16364532 |
| of the major phenolic acids formed during human microbial fermentation of tea, citrus, and soy flavonoid supplements, only 3,4-dihydroxyphenylacetic acid has antiproliferative activity. | dietary flavonoids are poorly absorbed from the gastrointestinal tract. colonic bacteria convert flavonoids into smaller phenolic acids (pa), which can be absorbed into the circulation and may contribute to the chemopreventive activity of the parent compounds. the purpose of our study was to determine whether flavonoids from green and black tea (gt, bt), citrus fruit with rutin (cf+r) and soy (s) supplements exposed to the same conditions in a dynamic in vitro model of the colon (tim-2) will for ... | 2006 | 16365058 |
| inhibition of cwr22rnu1 tumor growth and psa secretion in athymic nude mice by green and black teas. | cancer of the prostate gland (cap), the most common invasive malignancy and a major cause of cancer related deaths in male population in the usa, is an ideal candidate disease for chemoprevention because it is typically detected in elderly population with a relatively slower rate of growth and progression. many dietary phytochemicals are showing promising chemopreventive effects, at-least in pre-clinical models of cap. our published data in cell culture and animal studies, supported by the work ... | 2006 | 16387739 |
| inhibition of angiotensin converting enzyme activity by flavanol-rich foods. | angiotensin converting enzyme (ace) activity was evaluated in the presence of flavanol-rich foods, i.e., wines, chocolates, and teas, and of purified flavonoids. all foods assayed inhibited ace activity, red wines being more effective than white wine, and green tea more effective than black tea. the inhibition of ace activity was associated with both phenolic and flavanol content in the foods. when isolated polyphenols were assayed, procyanidins (dimer and hexamer) and epigallocatechin significa ... | 2006 | 16390204 |
| inhibitory effects of black tea theaflavin derivatives on 12-o-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears. | tea has been shown to possess several health beneficial properties primarily due to its polyphenolic content. the major polyphenolic compounds in black tea leaves are theaflavins (tfs) formed by oxidative coupling of catechins in tea leaves during its processing. in this paper, we report the characterization of 12-o-tetradecanoylphorbol-13-acetate (tpa)-induced mouse ear inflammatory model and the inhibitory effects of major black tea tfs derivatives on this inflammation. in addition, the effect ... | 2006 | 16404705 |
| neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. | teas represent a large family of plants containing high amounts of polyphenols that may confer health benefits in various diseases. recently, it has been hypothesized that tea consumption may also reduce the risk of age-related neurodegenerative pathologies. considering the deleterious role of beta-amyloid (abeta) in the aetiology of alzheimer's disease (ad), we investigated green and black tea extracts and flavan-3-ols (present as monomers and dimers in green and black forms, respectively) agai ... | 2006 | 16420415 |
| short-term bioaccumulation of vanadium when ingested with a tea decoction in streptozotocin-induced diabetic rats. | sodium orthovanadate suspended in a lichee black tea decoction effectively regulates blood glucose levels in rats with insulin-dependent, streptozotocin (stz)-induced diabetes. the primary advantage of vanadate delivery with the tea decoction over conventional systems that use water suspensions of vanadate is a significant reduction in the toxic side effects of vanadate. it is unknown if the tea alters the bioavailability of vanadate. male sprague-dawley rats were administered an intravenous inj ... | 2006 | 16423636 |
| chemoprevention of lung cancer by tea. | tea is the second only to water as the most consumed beverage in the world. both green and black teas have been studied for their health benefits for a variety of diseases, particularly cancer. lung cancer is the predominant cause of cancer mortality in developed countries. smokers' risk of lung cancer is 20 times that of persons who have never smoked. epidemiological studies on the cancer-preventive effects of tea produce inconsistent results, which could in part be attributed to the lack of a ... | 2006 | 16425282 |
| tumor-induced thymic involution via inhibition of il-7r alpha and its jak-stat signaling pathway: protection by black tea. | down-regulation of cell-mediated immune functions occurring at late stages of cancer may be related to the thymic involution since thymus is the major site of t cell maturation, proliferation, and differentiation. we found that in ehrlich's ascites carcinoma (eac)-bearing mice there was profound depletion of cd4+ and cd8+ cells in peripheral blood with severely damaged thymus on 21st day of tumor inoculation. however, treatment with black tea at an antitumor dose of 2.5% significantly reduced su ... | 2006 | 16428079 |
| green tea (camellia sinensis) extract ameliorates endotoxin induced sickness behavior and liver damage in rats. | immune activation, either by cytokines or endotoxin, elicits a constellation of nonspecific symptoms such as weakness, malaise, listlessness, fatigue, adipsia, anorexia, depression and anxiety collectively termed as sickness behavior. further, endotoxin administration in animals has been implicated in the pathogenesis of many types of liver disease. green tea, a common household drink, is rich in antioxidant polyphenols demonstrating inhibitory effects on cytokine production. the present study w ... | 2006 | 16444665 |
| neuroprotective and neurorescue effect of black tea extract in 6-hydroxydopamine-lesioned rat model of parkinson's disease. | in the present study, an attempt has been made to explore the neuroprotective and neuroreparative (neurorescue) effect of black tea extract (bte) in 6-hydroxydopamine (6-ohda)-lesioned rat model of parkinson's disease (pd). in the neuroprotective (bte + 6-ohda) and neurorescue (6-ohda + bte) experiments, the rats were given 1.5% bte orally prior to and after intrastriatal 6-ohda lesion respectively. a significant recovery in d-amphetamine induced circling behavior (stereotypy), spontaneous locom ... | 2006 | 16480889 |
| targeting angiogenesis with integrative cancer therapies. | an integrative approach for managing a patient with cancer should target the multiple biochemical and physiological pathways that support tumor development while minimizing normal tissue toxicity. angiogenesis is a key process in the promotion of cancer. many natural health products that inhibit angiogenesis also manifest other anticancer activities. the authors will focus on natural health products (nhps) that have a high degree of antiangiogenic activity but also describe some of their many ot ... | 2006 | 16484711 |
| antimicrobial activities of tea catechins and theaflavins and tea extracts against bacillus cereus. | we evaluated the antimicrobial activities of seven green tea catechins and four black tea theaflavins, generally referred to as flavonoids, as well as the aqueous extracts (infusions) of 36 commercial black, green, oolong, white, and herbal teas against bacillus cereus (strain rm3190) incubated at 21 degrees c for 3, 15, 30, and 60 min. the results obtained demonstrate that (i) (-)-gallocatechin-3-gallate, (-)-epigallocatechin-3-gallate, (-)-catechin-3-gallate, (-)-epicatechin-3-gallate, theafla ... | 2006 | 16496576 |
| triterpene saponins with gastroprotective effects from tea seed (the seeds of camellia sinensis). | six new triterpene saponins, theasaponins a(1) (1), a(2) (2), a(3) (3), f(1) (4), f(2) (5), and f(3) (6), were isolated from the saponin fraction of the seeds of camellia sinensis. the stereostructures of 1-6 were elucidated on the basis of chemical and physicochemical evidence. theasaponin a(2) (2) showed an inhibitory effect on ethanol-induced gastric mucosal lesions in rats at a dose of 5.0 mg/kg, p.o., and its activity was more potent than that of omeplazole. structure-activity relationships ... | 2006 | 16499314 |
| chronic black tea administration protects plasma proteins, plasma, liver and kidney lipids against oxidation. | black tea is known to have protective effects against plasma lipid and lipoprotein oxidation, but its influence on lipid peroxidation in tissue has been less studied. the effect of oral black tea consumption on protein oxidation has also not been demonstrated. the present study investigated the antioxidant effects of oral black tea consumption. | 2006 | 16501415 |
| green tea, black tea and colorectal cancer risk: a meta-analysis of epidemiologic studies. | experimental studies have supported tea as a chemopreventive agent for colorectal cancer. no quantitative summary of the epidemiologic evidence on tea and colorectal cancer risk has ever been performed. the current meta-analysis included 25 papers conducted in 11 countries across three continents (north america, asia and europe). summary odds ratios (ors) for highest versus non/lowest tea consumption levels were calculated based on fixed and random effects models. the meta-regression and stratif ... | 2006 | 16638787 |
| transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice. | epigallocatechin-3-gallate (egcg) is the most studied catechin in green tea (camellia sinensis). egcg and green tea are cancer preventive in many animal models, and numerous mechanisms have been proposed in cell lines. egcg is poorly bioavailable in man and rodents. we hypothesized that transdermal delivery of egcg could result in improved bioavailability. following application of egcg transdermal gel (50 mg kg(-1), t.d.) to skh-1 mice, egcg was observed in the epidermis (1365.7-121.0 ng g(-1)) ... | 2006 | 16640828 |
| plant growth promotion and induction of resistance in camellia sinensis by bacillus megaterium. | bacillus megaterium de bary trs-4 was isolated from tea rhizosphere and tested for its ability to promote growth and cause disease reduction in tea plants. in vivo studies revealed the ability of this bacterium to promote growth of tea plants very significantly. brown root rot disease, caused by fomes lamaoensis was markedly reduced by application of the bacterium to the soil. population of f. lamaoensis in soil before and after application of b. megaterium, as determined by elisa and dot-blot u ... | 2006 | 16721878 |
| protective effect of black tea against ethanol-induced oxidative modifications of liver proteins and lipids. | black tea has been recently ascertained as a source of water-soluble antioxidants that may enhance cellular antioxidant abilities. the present study was designed to investigate the efficacy of the preventive effect of black tea on oxidative modifications of liver lipids and proteins of 2-month-old rats intoxicated chronically (28 days) with ethanol. | 2006 | 16736070 |
| tea polyphenols and theaflavins are present in prostate tissue of humans and mice after green and black tea consumption. | green and black tea have shown promise in the chemoprevention of prostate cancer. the objective of this study was to determine the bioavailability and bioactivity of tea polyphenols (pp) and theaflavins in human serum and human and mouse tissues. a decaffeinated black tea diet was administered to c57bl/6 mice. pps and theaflavins were found in the small and large intestine, liver, and prostate in conjugated and free forms. the relative prostate bioavailability of theaflavin was 70% higher than t ... | 2006 | 16772446 |
| epicatechins purified from green tea (camellia sinensis) differentially suppress growth of gender-dependent human cancer cell lines. | the anticancer potential of catechins derived from green tea is not well understood, in part because catechin-related growth suppression and/or apoptosis appears to vary with the type and stage of malignancy as well as with the type of catechin. this in vitro study examined the biological effects of epicatechin (ec), epigallocatechin (egc), ec 3-gallate (ecg) and egc 3-gallate (egcg) in cell lines from human gender-specific cancers. cell lines developed from organ-confined (hh870) and metastatic ... | 2006 | 16786054 |
| evaluation of the hypolipemic property of camellia sinensisvar. ptilophylla on postprandial hypertriglyceridemia. | a naturally decaffeinated tea, camellia sinensis var. ptilophylla (cocoa tea), has long been popular in southern china as a healthy beverage. our experiments indicate that a single oral administration of 500 mg/kg of cocoa tea extract suppresses increases in plasma triacylgycerol (tg) levels when fed with 5 ml/kg of olive or lard oil in mice and that the inhibition rates are 22.9% and 31.5%, respectively, compared with controls. under the same condition, cocoa tea extract did not affect the leve ... | 2006 | 16819905 |
| chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways. | chemoprevention of colorectal cancer has become essential in the modern industrialized world as cancer of the large bowel has become one of the major causes of cancer mortality, second only to lung cancer. colon cancer integrates lifestyle factors and multistep genetic alterations, and without preventive intervention, a substantial part of the population is likely to develop colorectal cancer at some point during their lives. diet and nutrition clearly play a role in the etiology of colon cancer ... | 2006 | 16835502 |
| urinary flavonoids and phenolic acids as biomarkers of intake for polyphenol-rich foods. | estimation of dietary intake of polyphenols is difficult, due to limited availability of food composition data and bias inherent to dietary assessment methods. the aim of the present study was to evaluate the associations between the intake of polyphenol-rich foods and the urinary excretion of several phenolic compounds and therefore explore whether these phenolic compounds could be used as a biomarker of intake. fifty-three participants of the su.vi.max study (a randomised primary-prevention tr ... | 2006 | 16870009 |
| tea flavanols inhibit angiotensin-converting enzyme activity and increase nitric oxide production in human endothelial cells. | a diversity of pharmacological effects on the cardiovascular system have been reported for camellia sinensis: antioxidative, antiproliferative and anti-angiogenic activity, and nitric oxide synthase activation. the purpose of this study was to investigate if the connection between tea and angiotensin-converting enzyme (ace) and nitric oxide (no) might be an explanation of the pharmacological effects of tea on the cardiovascular system. cultured endothelial cells from human umbilical veins (huvec ... | 2006 | 16872562 |
| protection from experimental colitis by theaflavin-3,3'-digallate correlates with inhibition of ikk and nf-kappab activation. | inflammatory bowel disease (ibd) is associated with activation of nuclear factor kappa b (nf-kappab) involved in regulating the expression of inducible nitric oxide synthase (inos) and proinflammatory cytokine genes. as theaflavin-3,3'-digallate (tfdg), the most potent anti-oxidant polyphenol of black tea, down-regulates nf-kappab activation, we investigated if tfdg is beneficial in colonic inflammation by suppressing inos and proinflammatory cytokines. | 2006 | 16880762 |
| pre-exposure to a novel nutritional mixture containing a series of phytochemicals prevents acetaminophen-induced programmed and unprogrammed cell deaths by enhancing bcl-xl expression and minimizing oxidative stress in the liver. | from a disease-prevention perspective, recent progress in phytochemical and nutraceutical research clearly suggests (benefits outweigh the risk pattern). although powerful antioxidant properties have been the most acclaimed mechanism of action for these entities, the individual antioxidants studied in clinical trials do not appear to have consistent preventative effects. the actions of the antioxidant nutrients alone do not explain the observed health benefits of diets rich in fruits and vegetab ... | 2006 | 16902808 |