Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| myxobolus linzhiensis n. sp. (myxozoa: myxobolidae) from the gill filament of schizothorax oconnori lloyd (cyprinidae: schizothoracinae) in tibet, china: morphological and molecular characterization. | in this report, a new myxosporean species, myxobolus linzhiensis n. sp. (cnidaria: myxozoa: bivalvulida), was described from the endemic cyprinid schizothorax oconnori inhabiting the yarlung tsangpo river in the tibetan plateau, china. the whitish ellipsoidal plasmodia of m. linzhiensis n. sp. grew under the epithelium of gill filaments, 1.7-mm long and 0.4-mm wide, and were found in the 3 of 8 examined s. oconnori (37.5%). mature spores appeared suborbicular in frontal view, fusiform shaped in ... | 2017 | 28956158 |
| are the ttagg and ttaggg telomeric repeats phylogenetically conserved in aculeate hymenoptera? | despite the (ttagg)n telomeric repeat supposed being the ancestral dna motif of telomeres in insects, it was repeatedly lost within some insect orders. notably, parasitoid hymenopterans and the social wasp metapolybia decorata (gribodo) lack the (ttagg)n sequence, but in other representatives of hymenoptera, this motif was noticed, such as different ant species and the honeybee. these findings raise the question of whether the insect telomeric repeat is or not phylogenetically predominant in hym ... | 2017 | 28956077 |
| double salt ionic liquids based on 1-ethyl-3-methylimidazolium acetate and hydroxyl-functionalized ammonium acetates: strong effects of weak interactions. | the properties of double salt ionic liquids based on solutions of cholinium acetate ([ch][oac]), ethanolammonium acetate ([nh3(ch2)2oh][oac]), hydroxylammonium acetate ([nh3oh][oac]), ethylammonium acetate ([nh3ch2ch3][oac]), and tetramethylammonium acetate ([n(ch3)4][oac]) in 1-ethyl-3-methylimidazolium acetate ([c2mim][oac]) were investigated by nmr spectroscopy and x-ray crystallography. through mixture preparation, the solubility of [n(ch3)4][oac] is the lowest, and [ch][oac] shows a 3-fold ... | 2017 | 28956042 |
| suppression of mage-a10 alters the metastatic phenotype of tongue squamous cell carcinoma cells. | mage-a10 is a member of the mage protein family (melanoma associated antigen) which is overexpressed in cancer cells. although mage-a10 has been characterized for some time and is generally associated to metastasis its function remains unknown. here we describe experiments using as models oral squamous cell carcinoma (oscc) cell lines displaying increasing metastatic potential (ln1 and ln2). these cell lines were transduced with lentivirus particles coding for short hairpin against mage-a10 mrna ... | 2017 | 28955754 |
| enhanced production of xylanase by fusarium sp. bvkt r2 and evaluation of its biomass saccharification efficiency. | growth of fusarium sp. bvkt r2, a potential isolate of forest soils of eastern ghats on birchwood xylan in mineral salts medium (msm) under un-optimized conditions of 30 °c, ph of 5.0, 150 rpm and inoculum size of 5 agar plugs for 7 days, yielded titer of 1290 u/ml of xylanase (ec 3.2.1.8). the effect of various operating parameters such as different substrates and their concentration, additional carbon and nitrogen sources, incubation temperature, initial ph, agitation and inoculum size on the ... | 2017 | 28955648 |
| cloning and expression analysis of tps, and cryopreservation research of trehalose from antarctic strain pseudozyma sp. | trehalose is a non-reducing disaccharide sugar that widely exists in a variety of organisms, such as bacteria and eukaryotes except the vertebrates. it plays an important role in a number of critical metabolic functions especially in response to stressful environmental conditions. however, the biosynthetic pathways of trehalose in cold-adapted yeast and its responses to temperature and salinity changes remain little understood. in this study, the genome of antarctic-isolated pseudozyma sp. nj7 w ... | 2017 | 28955640 |
| optimization of physicochemical parameters influencing the production of prodigiosin from serratia nematodiphila rl2 and exploring its antibacterial activity. | in the present study, role of various physicochemical parameters influencing the production of antimicrobial pigment prodigiosin from serratia nematodiphila rl2 was determined and optimized. the pigment-producing strain was isolated and based on molecular characterization (16s rrna sequencing), was identified as s. nematodiphila rl2. the pigment produced by s. nematodiphila rl2 was characterized by thin layer chromatography (rf 0.94), spectrophotometrically (λmax 535 nm) and identified as prodig ... | 2017 | 28955635 |
| a halotolerant laccase from chaetomium strain isolated from desert soil and its ability for dye decolourization. | a novel fungal laccase produced by the ascomycete chaetomium sp. isolated from arid soil was purified and characterized and its ability to remove dyes was determined. extracellular laccase was purified 15-fold from the crude culture to homogeneity with an overall yield of 50% using ultrafiltration and anion-exchange chromatography. the purified enzyme was found to be a monomeric protein with a molecular mass of 68 kda, estimated by sds-page, and with an isoelectric point of 5.5. the optimal temp ... | 2017 | 28955626 |
| reactive oxygen species-scavenging system is involved in l-amino acid oxidase accumulation in pseudoalteromonas sp. b3. | to date, the mechanisms underlying the flavoprotein l-amino acid oxidase (laao) accumulation in cells remain unclear. in this study, using laao-producer pseudoalteromonas spp. as model organisms, we found that the cell biomass is negatively associated with laao accumulation, whereas the laao accumulation is positively associated with the reactive oxygen species (ros)-scavenging capability. the expression levels of ros-scavenging-associated genes were up-regulated with laao accumulation in pseudo ... | 2017 | 28955623 |
| characterization of ligninolytic enzyme production in white-rot wild fungal strains suitable for kraft pulp bleaching. | fungal strains identified by phylogenetic analysis of the its rdna region as trametes versicolor (cmu-ta01), irpex lacteus (cmu-84/13), and phlebiopsis sp. (cmu-47/13) are able to grow on and bleach kraft pulp (kp) in a simple solid-state fermentation (ssf) assay conducted in petri dishes. kappa number reductions obtained with phlebiopsis sp. (48.3%), t. versicolor (43%), and i. lacteus (39.3%), evidence their capability for lignin breakdown. scanning electron microscopy images of kp fibers from ... | 2017 | 28955616 |
| endophytic bacteria: a new source of bioactive compounds. | in recent years, bioactive compounds are in high demand in the pharmaceuticals and naturopathy, due to their health benefits to human and plants. microorganisms synthesize these compounds and some enzymes either alone or in association with plants. microbes residing inside the plant tissues, known as endophytes, also produce an array of these compounds. endophytic actinomycetes act as a promising resource of biotechnologically valuable bioactive compounds and secondary metabolites. endophytic st ... | 2017 | 28955612 |
| evaluation of styloid process morphology and calcification types in both genders with different ages and dental status. | the purpose of this study was to investigate the morphology and calcification pattern of the styloid process (sp) and to determine their relations with subjects' age, gender, and dental status. | 2017 | 28955593 |
| expression of ercc1, bcl-2, lin28a, and ki-67 as biomarkers of response to first-line platinum-based chemotherapy in patients with high-grade extrapulmonary neuroendocrine carcinomas or small cell lung cancer. | small cell lung cancer (sclc) and high-grade extrapulmonary neuroendocrine carcinomas (epnec) share similar histopathological features and treatment, but outcomes may differ. we evaluated in our study the expression of biomarkers associated with response rate (rr) to chemotherapy and overall survival (os) for these entities. | 2017 | 28955403 |
| the laci-family transcription factor, rbsr, is a pleiotropic regulator of motility, virulence, siderophore and antibiotic production, gas vesicle morphogenesis and flotation in serratia. | gas vesicles (gvs) are proteinaceous, gas-filled organelles used by some bacteria to enable upward movement into favorable air/liquid interfaces in aquatic environments. serratia sp. atcc39006 (s39006) was the first enterobacterium discovered to produce gvs naturally. the regulation of gv assembly in this host is complex and part of a wider regulatory network affecting various phenotypes, including antibiotic biosynthesis. to identify new regulators of gvs, a comprehensive mutant library contain ... | 2017 | 28955306 |
| intra- and inter-observer agreement in the ao and garnavos systems for diaphyseal humerus fracture. | the objective of this study was to compare inter- and intra-observer agreement using the garnavos and ao/asif systems for classifying humeral diaphysis fractures . | 2017 | 28955174 |
| postural control assessment in physically active and sedentary individuals with paraplegia. | the aim of this study was to evaluate functional independence and trunk control during maximum-range tasks in individuals with spinal cord injuries, who were divided into sedentary (ssi, n=10) and physically active (pasi, n=10) groups . | 2017 | 28955171 |
| struthers' ligament and supracondylar humeral process: an anatomical study and clinical implications. | the objective of this study was to determine the frequency and anatomical characteristics of struthers' ligament and the supracondylar humeral process and evaluate the clinical implications in compressive neuropathy of the median nerve . | 2017 | 28955169 |
| comparison between two types of abduction orthotics in treating congenital clubfoot. | the objective of this study was to analyze and compare the effectiveness of two types of abduction orthotics used for the feet, the denis-browne type (traditional) and the dobbs type (dynamic), with regard to maintenance of deformity correction and prevention of recurrence . | 2017 | 28955166 |
| design of a locator for designing the shortest incision for a polygonal dural window. | when a wide polygonal dural window is created, a short dural incision length is preferred by surgeons because suturing a wastefully long incision line during closure is troublesome. a locator to facilitate making the shortest dural incision when creating a polygonal dural window would be helpful. we geometrically analyzed the shortest incision design for a pentagonal dural window and produced a simple locator for intraoperatively implementing this design. the design for a pentagonal dural window ... | 2017 | 28954944 |
| elevation of three subspecies of lonsdalea quercina to species level: lonsdalea britannica sp. nov., lonsdalea iberica sp. nov. and lonsdalea populi sp. nov. | four subspecies of lonsdalea quercina (l. quercina subsp. quercina, l. quercina subsp. britannica, l. quercina subsp. iberica and l. quercina subsp. populi) were studied by genome sequence-derived average nucleotide identity (ani), phylogenetic analysis based on 16s rrna gene sequences, multilocus sequence analysis (mlsa) and phenotypic characteristics. in phylogenetic trees, based on 16s rrna gene sequences, and in mlsa data, the four subspecies were divided into four subclusters in the lonsdal ... | 2017 | 28954646 |
| asprobacter aquaticus gen. nov., sp. nov., a prosthecate alphaproteobacterium isolated from fresh water. | a novel gram-negative bacterium strain, drw22-8t, was isolated from fresh water taken at a depth of 22 m at daechung reservoir, republic of korea. the cells of strain drw22-8t were aerobic and motile with a single polar flagellum or non-motile (stalked), and formed creamy-white colonies on r2a agar. the phylogenetic analysis based on 16s rrna gene sequencing indicated that the strain formed a separate lineage within the order rhodobacterales, showing similarity values under 91.8 % with its close ... | 2017 | 28954645 |
| caldovatus sediminis gen. nov., sp. nov., a moderately thermophilic bacterium isolated from a hot spring. | a gram-stain-negative, ovoid-shaped, aerobic, non-motile, catalase- and oxidase-positive, and moderately thermophilic bacterial strain, designated strain yim 72346t, was isolated from a sediment sample collected from a hot spring in tengchong county, yunnan province, south-west china. growth occurred at 37-50 °c (optimum, 45 °c), at ph 6.0-9.0 (optimum, ph 6.5-7.0) and in the presence of 0.5-1.0 % (w/v) nacl (optimum, 0.5 %). the major cellular fatty acids were c18 : 1ω7c, c16 : 0, c19 : 0cyclo ... | 2017 | 28954642 |
| clusterin modulates transdifferentiation of non-small-cell lung cancer. | secreted clusterin (sclu), a 75-80 kda disulfide-linked heterodimeric protein, plays crucial roles in various pathophysiological processes, including lipid transport, tissue remodeling, cell apoptosis and reproduction. our previous studies demonstrated that sclu could influence cell apoptosis, proliferation, and invasion of non-small cell lung cancer (nsclc) cells. | 2017 | 28954633 |
| recent advances in biological production of erythritol. | erythritol is a natural sweetener commonly used in the food and pharmaceutical industries. produced by microorganisms as an osmoprotectant, it is an ideal sucrose substitute for diabetics or overweight persons due to its almost zero calorie content. currently, erythritol is produced on an industrial scale through the fermentation of sugars by some yeasts, such as moniliella sp. however, the popularity of erythritol as a sweetener is still small because of its high retail price. this creates an o ... | 2017 | 28954540 |
| brown algae padina sanctae-crucis børgesen: a potential nutraceutical. | padina sanctae-crucis børgesen is distributed worldwide in tropical and subtropical seas; belongs to the dictyotaceae family, and has proven to be an exceptional source of biologically active compounds. four compounds were isolated and identified, namely: dolastane diterpene new for the genus padina; phaeophytin and hidroxy-phaeophytin new for the family dictyotaceae, and; mannitol first described in this species. saturated fatty acids as compared to the percentages of unsaturated fatty acids we ... | 2017 | 28954390 |
| partial purification and characterization of the recombinant benzaldehyde dehydrogenase from rhodococcus ruber ukmp-5m. | benzaldehyde dehydrogenase (bzdh) is encoded by the xylc that catalyzes the conversion of benzaldehyde into benzoate in many pathways such as toluene degradation. | 2017 | 28959354 |
| genetic and biochemical characterization of 2-chloro-5-nitrophenol degradation in a newly isolated bacterium, cupriavidus sp. strain cnp-8. | compound 2-chloro-5-nitrophenol (2c5np) is a typical chlorinated nitroaromatic pollutant. to date, the bacteria with the ability to degrade 2c5np are rare, and the molecular mechanism of 2c5np degradation remains unknown. in this study, cupriavidus sp. strain cnp-8 utilizing 2-chloro-5-nitrophenol (2c5np) and meta-nitrophenol (mnp) via partial reductive pathways was isolated from pesticide-contaminated soil. biodegradation kinetic analysis indicated that 2c5np degradation by this strain was conc ... | 2017 | 28959252 |
| pnpm, a lysr-type transcriptional regulator activates the hydroquinone pathway in para-nitrophenol degradation in pseudomonas sp. strain wbc-3. | a lysr-type transcriptional regulator (lttr), pnpr, has previously been shown to activate the transcription of operons pnpa, pnpb, and pnpcdefg for para-nitrophenol (pnp) degradation in pseudomonas sp. strain wbc-3. further preliminary evidence suggested the possible presence of an lttr additional binding site in the promoter region of pnpcdefg. in this study, an additional lttr pnpm, which shows 44% homology to pnpr, was determined to activate the expression of pnpcdefg. interestingly, a pnpm-d ... | 2017 | 28959240 |
| druggability and binding site interaction studies of potential metabolites isolated from marine sponge aurora globostellata against human epidermal growth factor receptor-2. | to study the involvement of compounds stigmasterol and oleic acid isolated from marine sponge aurora globostellata and docking against the human epidermal growth factor receptor-2 in breast cancer. the comparative molecular docking was performed with the natural compounds from marine sponge and the synthetic drugs used in breast cancer treatment against the target her2. the molecular docking analysis was done using glide in schrodinger software package. the adme properties were calculated using ... | 2017 | 28959095 |
| vaterite induced by lysinibacillus sp. gw-2 strain and its stability. | studies on the formation and stability of vaterite by bacteria in experimental systems are of great importance for understanding the mechanism by which microbes contribute to carbonate mineralization. in this study, mineralization experiments using lysinibacillus sp. strain gw-2 were carried out for 72h under shaking conditions and aging experiments using biotic and chemically synthesized vaterite were performed for 60days in distilled water and air. our results indicate that lysinibacillus sp. ... | 2017 | 28958863 |
| long-term therapy with intravenous zoledronate increases the number of nonattached osteoclasts. | the purpose of this study was to investigate the influence of long-term therapy with intravenous zoledronate (za) on the healing of extraction sockets in rats. forty rats, divided into groups c (control) and z (zoledronate), received intravenous injections of either saline solution or za for 24 weeks. their right maxillary incisor was extracted. euthanasia was performed at 7 or 28 days postoperative. histomorphometric (newly formed bone area) and immunohistochemical (rankl, opg and trap) analyse ... | 2017 | 28958784 |
| modified conventional bioreactor for microalgae cultivation. | microalgae, a renewable source for third generation biofuel production, have a great potential if cultivated in high concentration economically. bottleneck lies with designing economical and efficient photobioreactor. in addition, proportional c and n inputs in the known media does not support high specific growth rate and high biomass build-up. nitrates in fermentation media, f/2 for nannochloropsis sp. and zarrouk's for arthrospiraplatensis, were modified. aeration and agitation were altered i ... | 2017 | 28988616 |
| associations between symptoms of depression and heart rate variability: an exploratory study. | major depressive disorder (mdd) is associated with decreased heart rate variability (hrv), a predictor of cardiovascular morbidity by many, but not all studies. this inconsistency could be due to the association of hrv with specific depressive symptoms. here, we investigated the association of hrv parameters with components of depressive symptoms from 120 mdd patients, at baseline of a published trial comparing the effect of sertraline to transcranial direct current stimulation. we used principa ... | 2017 | 28958456 |
| characterization of an alteromonas long-type ulvan lyase involved in the degradation of ulvan extracted from ulva ohnoi. | ulvan is a sulfated polysaccharide found in the cell wall of the green algae ulva. we first isolated several ulvan-utilizing alteromonas sp. from the feces of small marine animals. the strain with the highest ulvan-degrading activity, kul17, was analyzed further. we identified a 55-kda ulvan-degrading protein secreted by this strain and cloned the gene encoding for it. the deduced amino acid sequence indicated that the enzyme belongs to polysaccharide lyase family 24 and thus the protein was nam ... | 2017 | 28958183 |
| low-temperature single carbon nanotube spectroscopy of sp3 quantum defects. | aiming to unravel the relationship between chemical configuration and electronic structure of sp3 defects of aryl-functionalized (6,5) single-walled carbon nanotubes (swcnts), we perform low-temperature single nanotube photoluminescence (pl) spectroscopy studies and correlate our observations with quantum chemistry simulations. we observe sharp emission peaks from individual defect sites that are spread over an extremely broad, 1000-1350 nm, spectral range. our simulations allow us to attribute ... | 2017 | 28958146 |
| structure-based design of herg-neutral antihypertensive oxazalone and imidazolone derivatives. | angiotensin ii receptor type 1 (at1) antagonists are the most recent drug class against hypertension. recently first crystal structure of at1 receptor is deposited to the protein data bank (pdb id: 4yay). in this work, several molecular screening methods such as molecular docking and de novo design studies were performed and it is found that oxazolone and imidazolone derivatives reveal similar/better interaction energy profiles compared to the fda approved sartan molecules at the binding site of ... | 2017 | 28957753 |
| how myristyltrimethylammonium bromide enhances biomass harvesting and pigments extraction from synechocystis sp. pcc 6803. | myristyltrimethylammonium bromide (mtab) is a cationic surfactant used to improve biomass harvesting and pigment extraction form microalgae, but the mechanisms underlying its effectiveness are poorly defined. we document the mechanisms for enhanced harvesting and pigment extraction for the cyanobacterium synechocystis sp. pcc 6803 using measurements from flow cytometer, zeta potential, release of soluble components, and microscopy. harvesting efficiency increased as the mtab/biomass dose increas ... | 2017 | 28957695 |
| a hypothesis for the composition of the tardigrade brain and its implications for panarthropod brain evolution. | incredibly disparate brain types are found in metazoa, which raises the question of how this disparity evolved. ecdysozoa includes representatives that exhibit ring-like brains-the cycloneuralia-and representatives that exhibit ganglionic brains-the panarthropoda (euarthropoda, onychophora, and tardigrada). the evolutionary steps leading to these distinct brain types are unclear. phylogenomic analyses suggest that the enigmatic tardigrada is a closely related outgroup of a euarthropoda + onychop ... | 2017 | 28957526 |
| alternagin-c (alt-c), a disintegrin-like cys-rich protein isolated from the venom of the snake rhinocerophis alternatus, stimulates angiogenesis and antioxidant defenses in the liver of freshwater fish, hoplias malabaricus. | alternagin-c (alt-c) is a disintegrin-like protein isolated from rhinocerophis alternatus snake venom, which induces endothelial cell proliferation and angiogenesis. the aim of this study was to evaluate the systemic effects of a single dose of alternagin-c (0.5 mg·kg-1, via intra-arterial) on oxidative stress biomarkers, histological alterations, vascular endothelial growth factor (vegf) production, and the degree of vascularization in the liver of the freshwater fish traíra, hoplias malabaricu ... | 2017 | 28956818 |
| assessment of the antioxidant, cytotoxic, and genotoxic potential of the annona muricata leaves and their influence on genomic stability. | the popular use of annona muricata l. is based upon a range of medicinal purposes, and the plant exhibits biological activities including antihyperglycemic, antiparasitic, and antitumor activities. the objectives of this study were to examine the antioxidant, cytotoxic, and genotoxic potential of the hydroalcoholic extract of a. muricata leaves (ames), as well as its effects on genotoxicity induced by methyl methanesulfonate (mms) and hydrogen peroxide (h2o2). the results using 2,2-diphenyl-1-pi ... | 2017 | 28956726 |
| arsenic trioxide exposure impairs testicular morphology in adult male mice and consequent fetus viability. | the acute promyelocytic leukemia (apl) is a rare disease, affecting 0.1/100,000 individuals globally. despite significant advances in apl therapy, some patients still experience relapsed disease. currently, arsenic trioxide (as2o3) was found to be effective in relapsed apl treatment and considered as standard treatment for these cases. however, it has been shown that exposure to as2o3 may exert adverse effects on the male reproductive system since this substance might also induce apoptosis of ot ... | 2017 | 28956719 |
| intestinal barrier and gut microbiota: shaping our immune responses throughout life. | the gastrointestinal (gi) tract is considered the largest immunological organ in the body having a central role in regulating immune homeostasis. contrary to earlier belief, the intestinal epithelial barrier is not a static physical barrier but rather strongly interacts with the gut microbiome and cells of the immune system. this intense communication between epithelial cells, immune cells and microbiome will shape specific immune responses to antigens, balancing tolerance and effector immune fu ... | 2017 | 28956703 |
| copper-catalyzed synthesis of indol-3-yl α-(difluoromethyl)-α-(trifluoromethyl)carbinols: construction of difluoromethylated sp3 carbon centers. | an efficient copper-catalyzed synthesis of indol-3-yl α-(difluoromethyl)-α-(trifluoromethyl)carbinols is developed. the reaction proceeds in good to excellent yields through a friedel-crafts-type mechanism, and a variety of indoles with commonly occurring functional groups such as formyl, cyano, nitro, alkyloxide, and halogen are well tolerated. in addition, these carbinol products are readily transformed into diversified difluoromethylated dinitrile indol-3-yl derivatives. this strategy provide ... | 2017 | 28956615 |
| c(sp3)-h amination of 8-methylquinolines with azodicarboxylates under rh(iii) catalysis: cytotoxic evaluation of quinolin-8-ylmethanamines. | the rhodium(iii)-catalyzed c(sp3)-h amination reaction of 8-methylquinolines and azodicarboxylates is described. a cationic rhodium catalyst in the presence of lithium acetate and lithium carbonate was found to be an optimal catalytic system for the construction of quinolin-8-ylmethanamine derivatives, which were evaluated for in vitro cytotoxicity against human breast adenocarcinoma cells (mcf-7) and human prostate adenocarcinoma cells (lncap). | 2017 | 28956557 |
| spatial distribution of zika virus infection in northeastern colombia. | in this study, we investigated the weekly reported spatio-temporal distribution and topographic risk factors for zika virus (zikv) infection in northeastern colombia. weekly reported surveillance data, including clinical, suspected and confirmed cases from the ongoing zikv epidemic in the santander and norte de santander departments (santanderes) in colombia were used to estimate cumulative incidence rates. spatial analysis was performed to develop hot spot maps and to identify spatial topograph ... | 2017 | 28956541 |
| effects of deslorelin acetate on plasma testosterone concentrations in captive yellow-bellied sliders (trachemys scripta sp.). | in europe, the yellow-bellied slider (trachemys scripta sp.) is a non-native species in competition with native freshwater turtles. research on contraception could be useful to control the captive population. identifying a method of contraception in chelonians would potentially help to control aggression in other chelonian species. the objective of the current study was to evaluate the effects of a single 4.7-mg deslorelin acetate implant on plasma testosterone concentrations in yellow-bellied s ... | 2017 | 28956487 |
| the mechanism of action of (-)-lomaiviticin a. | (-)-lomaiviticin a (4) is a complex c2-symmetric bacterial metabolite that contains two diazofluorene functional groups. the diazofluorene consists of naphthoquinone, cyclopentadiene, and diazo substituents fused through a σ- and π-bonding network. additionally, (-)-lomaiviticin a (4) is a potent cytotoxin, with half-maximal inhibitory potency (ic50) values in the low nanomolar range against many cancer cell lines. because of limitations in supply, its mechanism of action had remained a "black b ... | 2017 | 28956437 |
| [aide encodes an n-acyl homoserine lactonase in acinetobacter]. | quorum sensing (qs) is a cell-cell communication mechanism that allows bacterial populations to coordinate gene expression in response to cell density. n-acylhomoserine lactones (ahl) are used as quorum-sensing signal molecules by many gram negative bacteria. acinetobacter sp. 77, an ahl-degrading bacterium, was isolated in our previous work. the gene aide for ahl inactivation was cloned in this study by screening a genomic dna library. the deduced protein aide is 268 amino acids in length and s ... | 2017 | 28956406 |
| rhodoferax koreense sp. nov, an obligately aerobic bacterium within the family comamonadaceae, and emended description of the genus rhodoferax. | gram-staining-negative, uniflagellated, rod-shaped, designated as dcy110t, was isolated from sludge located in gangwon province, republic of korea. the phylogenetic tree of 16s rrna gene sequence showed that the strain dcy110t belonged to the genus rhodoferax with a close similarity to rhodoferax saidenbachensis dsm 22694t (97.7%), rhodoferax antarcticus dsm 24876t (97.5%), rhodoferax ferrireducens dsm 15236t (97.3%), and rhodoferax fermentans jcm 7819t (96.7%). the predominant isoprenoid quinin ... | 2017 | 28956356 |
| mutation of the cyclic di-gmp phosphodiesterase gene in burkholderia lata sk875 attenuates virulence and enhances biofilm formation. | burkholderia sp. is a gram-negative bacterium that commonly exists in the environment, and can cause diseases in plants, animals, and humans. here, a transposon mutant library of a burkholderia lata isolate from a pig with swine respiratory disease in korea was screened for strains showing attenuated virulence in caenorhabditis elegans. one such mutant was obtained, and the tn5 insertion junction was mapped to rpfr, a gene encoding a cyclic di-gmp phosphodiesterase that functions as a receptor. ... | 2017 | 28956352 |
| effects of metal ions on the cultivation of an oleaginous microalga chlorella sp. | a coupling technique to purify wastewater for lipid production based on microalgae is attractive and promising for its potential to clean water and as biofuel feedstocks. metal ions from wastewater might be involved in microalgal cultivation. in this study, the effects of metal ions on algal growth, lipid-producing potential, and water purifying capability of chlorella sp. hq were investigated. the effects of metal ions (cr6+, cu2+, mn2+, zn2+, fe3+, na+, and k+) on alga lipid production combine ... | 2017 | 28956234 |
| novel bacteria capable of degrading phenanthrene in activated sludge revealed by stable-isotope probing coupled with high-throughput sequencing. | the indigenous microorganisms responsible for degrading phenanthrene (phe) in activated biosludge were identified using dna-based stable isotope probing. besides the well-known phe degraders burkholderia, ralstonia, sinobacteraceae and arthrobacter, we for the first time linked the taxa paraburkholderia and kaistobacter with in situ phe biodegradation. analysis of pah-rhdα gene detected in the heavy dna fraction of 13c-phe treatment suggested the mechanisms of horizontal gene transfer or inter-s ... | 2017 | 28956196 |
| prostaglandin e2 restrains human treg cell differentiation via e prostanoid receptor 2-protein kinase a signaling. | regulatory t cells (treg cells) belong to a class of immunosuppressive cells that control the pathological changes of autoimmunity and inflammation. prostaglandin e2 (pge2) is a potent lipid mediator of immune inflammation including rheumatoid arthritis (ra) that exerts its effects via four subtypes of g-protein-coupled receptors (ep1-4). the ability of pge2 to regulate human treg differentiation has not yet been reported. in the current study, we investigated the effects of pge2 on the differen ... | 2017 | 28963072 |
| the role of lsa23 to mediate the interaction of leptospira interrogans with the terminal complement components pathway. | leptospirosis is a severe worldwide zoonotic disease caused by pathogenic leptospira spp. it has been demonstrated that pathogenic leptospires are resistant to the bactericidal activity of normal human serum while saprophytic strains are susceptible. pathogenic strains have the ability to bind soluble complement regulators and these activities are thought to contribute to bacterial immune evasion. one strategy used by some pathogens to evade the complement cascade, which is not well explored, is ... | 2017 | 28963011 |
| newly discovered role of the heterotrophic nanoflagellate katablepharis japonica, a predator of toxic or harmful dinoflagellates and raphidophytes. | heterotrophic nanoflagellates are ubiquitous and known to be major predators of bacteria. the feeding of free-living heterotrophic nanoflagellates on phytoplankton is poorly understood, although these two components usually co-exist. to investigate the feeding and ecological roles of major heterotrophic nanoflagellates katablepharis spp., the feeding ability of katablepharis japonica on bacteria and phytoplankton species and the type of the prey that k. japonica can feed on were explored. furthe ... | 2017 | 28962983 |
| interactions between the mixotrophic dinoflagellate takayama helix and common heterotrophic protists. | the phototrophic dinoflagellate takayama helix that is known to be harmful to abalone larvae has recently been revealed to be mixotrophic. although mixotrophy elevates the growth rate of t. helix by 79%-185%, its absolute growth rate is still as low as 0.3d-1. thus, if the mortality rate of t. helix due to predation is high, this dinoflagellate may not easily prevail. to investigate potential effective protistan grazers on t. helix, feeding by diverse heterotrophic dinoflagellates such as engulf ... | 2017 | 28962979 |
| mixotrophy in the marine red-tide cryptophyte teleaulax amphioxeia and ingestion and grazing impact of cryptophytes on natural populations of bacteria in korean coastal waters. | cryptophytes are ubiquitous and one of the major phototrophic components in marine plankton communities. they often cause red tides in the waters of many countries. understanding the bloom dynamics of cryptophytes is, therefore, of great importance. a critical step in this understanding is unveiling their trophic modes. prior to this study, several freshwater cryptophyte species and marine cryptomonas sp. and geminifera cryophila were revealed to be mixotrophic. the trophic mode of the common ma ... | 2017 | 28962973 |
| the role of wine polysaccharides on salivary protein-tannin interaction: a molecular approach. | polysaccharides are described to inhibit aggregation between food polyphenols and salivary proteins (sp) and may hence lead to astringency modulation. in this work, the effect of two wine polysaccharides (arabinogalactan proteins-agps and rhamnogalacturonan ii- rgii) on sp-polyphenol interaction was evaluated. in general, both polysaccharides were effective to inhibit or reduce sp-polyphenol interaction and aggregation. they can act by two different mechanisms (ternary or competitive) depending ... | 2017 | 28962798 |
| synthesis and characterization of a multi-sensitive polysaccharide hydrogel for drug delivery. | salecan is a novel water soluble polysaccharide produced by a salt-tolerant strain agrobacterium sp. zx09. poly(dimethylaminoethyl methacrylate) (pdmaema) is a ph, thermo, and ionic strength multi-sensitive polymer with anti-bacterial property. here, we report a semi-interpenetrating polymer network (semi-ipn) hydrogel based on salecan and pdmaema. the obtained hydrogel is simultaneous sensitive to ph, ionic strength and temperature: the swelling ratio maximizes at ph 1.2 and shrinks at ph value ... | 2017 | 28962769 |
| self-aggregates of 3,6-o,o'-dimyristoylchitosan derivative are effective in enhancing the solubility and intestinal permeability of camptothecin. | the aim of this work was to investigate the potential of a new 3,6-o,o'-dimyristoyl derivative amphiphilic chitosan (dmch), in improving the solubility of camptothecin (cpt), a hydrophobic anticancer drug, and its potential oral delivery. ftir, 1h nmr and solid-state 13c nmr spectroscopy were used to characterize dmch and to determine its average degree of substitution (ds¯=6.8%). dmch/cpt micelles size ranged from (281-357nm), zeta potential (+32-50mv) of encapsulation efficiency of 42-100%. th ... | 2017 | 28962756 |
| a unique heterologous fibrin sealant (hfs) as a candidate biological scaffold for mesenchymal stem cells in osteoporotic rats. | the injection of mesenchymal stem cells (mscs) directly into the bone of osteoporotic (op) patients for rapid recovery has been studied worldwide. scaffolds associated with mscs are used to maintain and avoid cell loss after application. a unique heterologous fibrin sealant (hfs) derived from snake venom was evaluated for the cytotoxicity of its main components and as a three-dimensional biological scaffold for mscs to repair a critical femur defect in osteoporotic rats. | 2017 | 28962655 |
| perspectives and experiences of community health workers in brazilian primary care centers using m-health tools in home visits with community members. | mobile health (m-health) tools are a promising strategy to facilitate the work of community health workers (chws) in low- and middle-income countries (lmics). despite their potential value, little is known about chws' experiences working with m-health tools in their outreach activities with community members. | 2017 | 28962569 |
| reducing capacity and enzyme activity of chromate reductase in a chrt-engineered strain. | in order to remediate the metal-contaminated soil and water ecosystems with microorganisms, an engineered strain, which contained the chromate reductase chrt gene from serratia sp. s2, was studied in detail for its cr (vi) reduction efficiency, optimal culture condition and chromate reductase activity. results demonstrated that the engineered strain had a high cr (vi) reduction rate of up to 40% at a concentration of 50 mg/l after being cultured for 48 h. additionally, the optimal culture condit ... | 2017 | 28962168 |
| soil microbial community dynamics and assembly under long-term land use change. | we evaluated the bacterial and archaeal community dynamics and assembly in soils under forest, grassland and no-till cropping, using a high-throughput shotgun metagenomics approach. no significant alterations in alpha diversity were observed among different land uses, but beta diversity in grassland was lower than that observed in forest and no-till soils. grassland communities showed assembly that predominantly followed the neutral model, i.e. high homogenizing selection with moderate dispersio ... | 2017 | 28961809 |
| enteroaggregative escherichia coli with uropathogenic characteristics are present in feces of diarrheic and healthy children. | enteroaggregative escherichia coli (eaec) has been recently associated with urinary tract infections (uti). since eaec are found in feces of both diarrheic and asymptomatic individuals, their presence in the intestine may be a source of uti. in this study, we detected in feces of diarrheic and healthy children a subset of eaec strains with genetic markers of extraintestinal pathogenic e. coli (expec). mlst grouped these eaec with expec markers in three main clusters along with prototypes strains ... | 2017 | 28961708 |
| bioactive and biocontrol potential of endophytic fungi associated with brugmansia aurea lagerh. | this study describes 32 fungal endophytes isolated from different tissues of brugmansia aurea lagerh. each fungal strain was authenticated based on internal transcribed spacer rdna sequence. phylogenetic analysis showed that these fungi are distributed in three classes, seven orders and 12 genera. the dichloromethane extracts of endophytic strains were screened for anticancer and antimicrobial activity. anticancer activity of extracts against human cancer cell lines revealed that 50% strains are ... | 2017 | 28961698 |
| graphene quantum dots electrochemistry and sensitive electrocatalytic glucose sensor development. | graphene quantum dots (gqds), derived from functionalized graphene precursors are graphene sheets a few nanometers in the lateral dimension having a several-layer thickness. they are zero-dimensional materials with quantum confinement and edge site effects. intense research interest in gqds is attributed to their unique physicochemical phenomena arising from the sp²-bonded carbon nanocore surrounded with edged plane functional moieties. in this work, gqds are synthesized by both solvothermal and ... | 2017 | 28961225 |
| halogen bonds formed between substituted imidazoliums and n bases of varying n-hybridization. | heterodimers are constructed containing imidazolium and its halogen-substituted derivatives as lewis acid. n in its sp³, sp² and sp hybridizations is taken as the electron-donating base. the halogen bond is strengthened in the cl < br < i order, with the h-bond generally similar in magnitude to the br-bond. methyl substitution on the n electron donor enhances the binding energy. very little perturbation arises if the imidazolium is attached to a phenyl ring. the energetics are not sensitive to t ... | 2017 | 28961202 |
| a marine bacterium, bacillus sp. isolated from the sediment samples of algoa bay in south africa produces a polysaccharide-bioflocculant. | bioflocculants mediate the removal of suspended particles from solution and the efficiency of flocculation is dependent on the characteristics of the flocculant. apart from the merits of biodegradability and harmlessness, bioflocculants could be viable as industrially relevant flocculants as they are a renewable resource. additionally, the shortcomings associated with the conventionally used flocculants such as aluminium salts and acrylamide polymers, which include dementia and cancer, highlight ... | 2017 | 28961180 |
| diaporisoindoles a-c: three isoprenylisoindole alkaloid derivatives from the mangrove endophytic fungus diaporthe sp. sysu-hq3. | diaporisoindoles a (1) and b (2), two novel isoprenylisoindole alkaloids, and an unusual diisoprenylisoindole dimer diaporisoindole c (3), together with a precursor tenellone c (4) were all isolated from the endophytic fungus diaporthe sp. sysu-hq3. the absolute configurations of 1-4 were elucidated by spectroscopic analysis, x-ray diffraction, and quantum chemical calculations. diaporisoindole a (1) and tenellone c (4) exhibited inhibitory activity against mycobacterium tuberculosis protein tyr ... | 2017 | 28961015 |
| smart fluid system dually responsive to light and electric fields: an electrophotorheological fluid. | electrophotorheological (epr) fluids, whose rheological activity is dually responsive to light and electric fields (e fields), is formulated by mixing photosensitive spiropyran-decorated silica (sp-ssio2) nanoparticles with zwitterionic lecithin and mineral oil. a reversible photorheological (pr) activity of the epr fluid is developed via the binding and releasing mechanism of lecithin and merocyanine (mc, a photoisomerized form of sp) under ultraviolet (uv) and visible (vis) light applications. ... | 2017 | 28960964 |
| polymerization of coniferyl alcohol by mn3+ -mediated (enzymatic) oxidation: effects of h2 o2 concentration, aqueous organic solvents, and ph. | the objective of this study was to evaluate the ability of one versatile peroxidase and the biocatalytically generated complex mn(iii)-malonate to polymerize coniferyl alcohol (ca) to obtain dehydrogenation polymers (dhps) and to characterize how closely the structures of the formed dhps resemble native lignin. hydrogen peroxide was used as oxidant and mn2+ as mediator. based on the yields of the polymerized product, it was concluded that the enzymatic reaction should be performed in aqueous sol ... | 2017 | 28960884 |
| effect of asymmetric tension on biomechanics and metabolism of vertebral epiphyseal plate in a rodent model of scoliosis. | to investigate the effect of asymmetric tension on idiopathic scoliosis (is) and to understand its pathogenic mechanism. | 2017 | 28960815 |
| surfactant protein d multimerization and gene polymorphism in copd and asthma. | a structural single nucleotide polymorphism rs721917 in the surfactant protein d (sp-d) gene, known as met11thr, was reported to influence the circulating levels and degree of multimerization of sp-d and was associated with both copd and atopy in asthma. moreover, disease-related processes are known to degrade multimerized sp-d, however, the degree of the protein degradation in these diseases is not clarified. we aimed to determine the distribution of multimerized (high molecular weight (hmw)) a ... | 2017 | 28960651 |
| total synthesis of (-)-spiroleucettadine. | one of a number of intriguing new alkaloids isolated from the leucetta sp. sponge in 2004, spiroleucettadine displayed unique structural features on a restricted scaffold: a trans-fused 5,5-bicyclic ring system together with an amino hemiketal moiety. attempts to synthesize the initially proposed structure failed, raising questions as to its veracity, and structure revision ensued in 2008; no successful synthetic approach has been reported to date. herein, we describe the enantiospecific total s ... | 2017 | 28960638 |
| jak1/2 inhibitors azd1480 and cyt387 inhibit canine b-cell lymphoma growth by increasing apoptosis and disrupting cell proliferation. | canine diffuse large b-cell lymphoma (dlbcl) is a common and aggressive hematologic malignancy. the lack of conventional therapies with sustainable efficacy warrants further investigation of novel therapeutics. the janus kinase (jak) and signal transducer and activator of transcription (stat) pathways play important roles in the pathogenesis of hematologic malignancies in humans including dlbcls. azd1480 and cyt387 are novel jak1/2 inhibitors that have been used in clinical trials for treating v ... | 2017 | 28960447 |
| antimicrobial effectiveness of combinations of oxidant and chelating agents in infected dentine: an ex vivo confocal laser scanning microscopy study. | to evaluate the intratubular antimicrobial activity of several oxidant and chelating agents associated with or without surfactants in experimentally infected root canals, using confocal laser scanning microscopy. | 2017 | 28960350 |
| in-vivo monitoring of infectious diseases in living animals using bioluminescence imaging. | traditional methods of localizing and quantifying the presence of pathogenic microorganisms in living experimental animal models of infections have mostly relied on sacrificing the animals, dissociating the tissue and counting the number of colony forming units. however, the discovery of several varieties of the light producing enzyme, luciferase, and the genetic engineering of bacteria, fungi, parasites and mice to make them emit light, either after administration of the luciferase substrate, o ... | 2017 | 28960132 |
| lipidomic alterations of in vitro macrophage infection by l. infantum and l. amazonensis. | particular lipid profiles have been found in two different protozoa of the leishmania genus. leishmania infantum, a visceral leishmaniasis causative agent and leishmania amazonensis, a cutaneous leishmaniasis, reveal distinctive lipid contents of phosphatidylethanolamine and phosphatidylserine plasmalogens, sphingolipids, phosphatidylinositols, phosphatidylcholine, and phosphatidylethanolamine, which have been shown to be related to species, life-cycle of the parasite, and macrophage infection. ... | 2017 | 28960008 |
| leptocneria vinarskii sp. nov. (lepidoptera: erebidae: lymantriinae), an overlooked wallacean lineage of the australian genus. | the tussock moth genus leptocneria butler, 1886 (lepidoptera: erebidae: lymantriinae) has been considered an entirely australian taxon that includes two species: l. reducta (walker, 1855) and l. binotata butler, 1886. however, we discovered a divergent lineage of leptocneria inhabiting flores island, lesser sundas, indonesia. here, we describe this lineage as the third species of the genus, l. vinarskii bolotov, kondakov et spitsyn sp. nov. the new species is sister to l. reducta but differs fro ... | 2017 | 28963487 |
| biogenic manganese oxide nanoparticle formation by a multimeric multicopper oxidase mnx. | bacteria that produce mn oxides are extraordinarily skilled engineers of nanomaterials that contribute significantly to global biogeochemical cycles. their enzyme-based reaction mechanisms may be genetically tailored for environmental remediation applications or bioenergy production. however, significant challenges exist for structural characterization of the enzymes responsible for biomineralization. the active mn oxidase in bacillus sp. pl-12, mnx, is a complex composed of a multicopper oxidas ... | 2017 | 28963463 |
| draft genome sequence of pseudomonas sp. strain drbhi1 (phylum proteobacteria). | here, we report the draft genome sequence of pseudomonas sp. strain drbhi1. the total assembly length is 5,649,751 bp in 146 contigs. this strain was isolated from zebrafish (danio rerio) feces. | 2017 | 28963227 |
| draft genome sequence of a gordonia sp. isolated from the soil of a red alder plant. | a gordonia species was cultured from soil of a red alder (alnus rubra) plant. here we present the assembled and annotated genome sequence to aid investigations into the potential of this organism as a symbiont and comparative studies of the genus gordonia. | 2017 | 28963216 |
| accuracy of serum ige concentrations and papule diameter in the diagnosis of cow's milk allergy. | to compare serum concentrations of specific ige and mean papule diameters induced in the immediate skin reactivity test with cow's milk (cm) and its fractions with results of the oral challenge test (oct), and to establish cutoff points capable of predicting clinical reactivity to cm in patients treated at a referral service. | 2017 | 28963879 |
| human parainfluenza virus surveillance in pediatric patients with lower respiratory tract infections: a special view of parainfluenza type 4. | characterize the role of human parainfluenza virus and its clinical features in brazilian children under 2 years of age presenting with acute lower respiratory tract infections. | 2017 | 28963878 |
| unveiling the biotransformation mechanism of indole in a cupriavidus sp. strain. | indole, an important signaling molecule as well as a typical n-heterocyclic aromatic pollutant, is widespread in nature. however, the biotransformation mechanisms of indole are still poorly studied. here, we sought to unlock the genetic determinants of indole biotransformation in strain cupriavidus sp. she based on genomics, proteomics and functional studies. a total of 177 proteins were notably altered (118 up- and 59 downregulated) in cells grown in indole mineral salt medium when compared wit ... | 2017 | 28963777 |
| stereoselective direct chlorination of alkenyl mida boronates: divergent synthesis of e and z α-chloroalkenyl boronates. | the individual molecules of α-chloroalkenyl boronates include both an electrophilic c-cl bond and a nucleophilic c-b bond, which makes them intriguing organic synthons. reported herein is a stereodivergent synthesis of both e and z α-chloroalkenyl n-methyliminodiacetyl (mida) boronates through the direct chlorination of alkenyl mida boronates using tbuocl and phsecl reagents, respectively. both reaction processes are stereospecific and the use of sp3 -b mida boronate is the key contributor to th ... | 2017 | 28963766 |
| ethical and legal aspects in the care of singers and actors. | 2017 | 28964692 | |
| exercise training improves hypertension-induced autonomic dysfunction without influencing properties of peripheral cardiac vagus nerve. | we examined the vagal transfer function of autonomic heart rate (hr) control in anesthetized sedentary and exercise-trained spontaneously hypertensive rats (shr). to this end, male shr and wystar-kyoto (wky) rats with 48-50weeks of age-old were divided into 4 groups: sedentary (shrs, n=12) and trained (shrt, n=14) hypertensive rats, sedentary (wkys, n=13) and trained (wkyt, n=13) normotensive rats. the trained groups were submitted to swimming protocol for 9weeks. blood pressure (bp), hr, hr var ... | 2017 | 28964689 |
| complete calcified ureteral stent: a combined 1-session approach. | to demonstrate a successful 1-session approach to a complete calcified ureteral stent, preserving the affected kidney without complications. | 2017 | 28964566 |
| author reply. | 2017 | 28964564 | |
| milk and serum il-4, il-6, il-10, and amyloid a concentrations in cows with subclinical mastitis caused by coagulase-negative staphylococci. | the aim of the study was to evaluate the concentrations of cytokines il-4, il-6, and il-10 and acute phase protein amyloid a in milk and in serum from cows with subclinical mastitis caused by coagulase-negative staphylococci and from healthy cows. the blood and milk samples were obtained from 35 midlactation, multiparous (between parities 2 and 4) holstein-friesian cows. in the milk samples from 20 cows with subclinical mastitis, the following species of staphylococcus were detected: staphylococ ... | 2017 | 28964518 |
| performance of first trimester biochemical markers and mean arterial pressure in prediction of early-onset pre-eclampsia. | to develop a predictive risk model for early-onset pre-eclampsia (eo-pe) using maternal characteristics, combined screening markers, previously reported biomarkers for pe and mean arterial pressure (map). | 2017 | 28964327 |
| expression of calcium-binding proteins s100a8, s100a9 and s100a12 in otitis media. | calgranulins (calcium-binding proteins s100a8, s100a9 and s100a12) are predominant cytoplasmic proteins of neutrophils and produced by various cells, playing multiple functions in innate immunity and the inflammatory process. although up-regulated expression of s100a8 and s100a9 genes were observed in an animal model of otitis media (om), their expressions have not been studied in human middle ear epithelial cells in response to the om pathogen or in patients with recurrent or chronic om (recurr ... | 2017 | 28964306 |
| the effect of pneumococcal conjugate vaccines on incidence and microbiology associated with complicated acute otitis media. | the objectives of this study were to investigate the incidence of complicated acute otitis media (caom) as well as the associated microbiology before and after introduction of the 7- and 13-valent pneumococcal conjugate vaccines (pcv-7 and -13), respectively. caom comprises "heavy" aom (aom demanding hospitalization), mastodismus (m) and acute mastoiditis (am). | 2017 | 28964304 |
| cryogenic stm in 3d vector magnetic fields realized through a rotatable insert. | spin-polarized scanning tunneling microscopy (sp-stm) performed in vector magnetic fields promises atomic scale imaging of magnetic structure, providing complete information on the local spin texture of a sample in three dimensions. here, we have designed and constructed a turntable system for a low temperature stm which in combination with a 2d vector magnet provides magnetic fields of up to 5 t in any direction relative to the tip-sample geometry. this enables stm imaging and spectroscopy to b ... | 2017 | 28964195 |
| polymorphisms in siglec1 contribute to susceptibility to pulmonary active tuberculosis possibly through the modulation of il-1ß. | siglec-1/cd169 is a sialoadhesin expressed by macrophages thought to function in cell-to-cell interactions. in the lung, the expression of siglec-1 is specific for alveolar macrophages and single nucleotide polymorphisms (snps) in siglec1 have been recently associated with asthma severity. taking in account the role of alveolar macrophages in the control of m. tuberculosis and the poor literature about the contribution of siglec1 genetics in m. tuberculosis susceptibility and development of pulm ... | 2017 | 28964857 |
| cytotoxicity, genotoxicity and antibacterial activity of poly(vinyl alcohol)-coated silver nanoparticles and farnesol as irrigating solutions. | to evaluate the cytotoxicity, genotoxicity and antibacterial activity of poly(vinyl alcohol)-coated silver nanoparticles (agnps-pva) and farnesol (far). | 2017 | 28965044 |
| redox imbalance due to the loss of mitochondrial nad(p)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice. | the mechanisms by which a high fat diet (hfd) promotes non-alcoholic fatty liver disease (nafld) appear to involve liver mitochondrial dysfunctions and redox imbalance. we hypothesized that a hfd would increase mitochondrial reliance on nad(p)-transhydrogenase (nnt) as the source of nadph for antioxidant systems that counteract nafld development. therefore, we studied hfd-induced liver mitochondrial dysfunctions and nafld in c57unib.b6 congenic mice with (nnt+/+) or without (nnt-/-) nnt activity ... | 2017 | 28964917 |
| lactate determination in pleural and abdominal effusions: a quick diagnostic marker of exudate-a pilot study. | pleural or abdominal effusions are frequent findings in icu and internal medicine patients. diagnostic gold standard to distinguish between transudate and exudate is represented by "light's criteria," but, unfortunately, the chemical-physical examination for their calculation is not a rapid test. pursuing an acid-base assessment of the fluid by a blood-gas analyzer, an increase of lactate beyond the normal serum range is reported in the exudative effusions. the advantages of this test are that i ... | 2017 | 28965174 |