Publications

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the influence of maternal effects on the response of fast and slow growing chickens to a marek's disease virus. 19734754048
neutralization studies with marek's disease virus and turkey herpesvirus.use of marek's disease virus (mdv) in a neutralization test presents several problems, which are described, making this potentially useful test difficult. to obviate these difficulties, a plaque reduction test has been designed based on cross-neutralization of turkey herpesvirus (hvt) by serum-neutralizing mdv. the technique for such a neutralization test is outlined. kinetics of development of neutralizing antibodies in chickens inoculated with hvt and mdv are described. the neutralization test ...19734767297
[a study of the properties of the kekava strain of marek's disease virus in experiments on chickens]. 19734789250
released and extracted virions of marek's disease virus. 19734797375
immunological surveillance against neoplasia. 19734376812
detecting marek's disease herpesvirus: evaluation of biological systems. 19734197288
falcon herpesvirus, the etiologic agent of inclusion body disease of falcons.a viral agent has been isolated from five fatal cases of naturally occurring inclusion body disease in three different falcon species, namely, the prairie falcon (falco mexicanus), the red-headed falcon (f. chiquera), and the peregrine falcon (f. peregrinus). the virus has been shown to possess the physical, chemical, and biological properties of a herpesvirus and has been used to reproduce inclusion body disease in the prairie falcon, merlin (f. columbarius), and american kestrel (f. sparverius ...19734352453
oncogenic marek's disease herpesvirus in avian encephalitis (temporary paralysis). 19734355225
public health implications of marek's disease virus and herpesvirus of turkeyes. studies on human and subhuman primates. 19734355599
protection of chickens against marek's disease virus jm-v strain with statolon and exogenous interferon. 19734358305
a comparative study of marek's disease virus proteins. 19734360181
biological and biochemical evidence for an interaction between marek's disease herpesvirus and avian leukosis virus in vivo.the dna-containing epstein-barr herpesvirus has been implicated in the etiology of burkitt's lymphoma, a malignant tumor of children in africa. recently, however, particles possessing four biochemical characteristics of rna tumor viruses have also been identified in these tumors. the fact that both types of viruses are found suggests that an interaction between them may be playing a role in the etiology of burkitt's lymphoma. to explore this possibility with a defined animal model, experiments w ...19734361680
susceptibility of mammalian (hamster) cell culture to infection with cellular and cell-free type ii leukosis (marek's disease) virus. 19734348217
immunoglobulin response in experimental infection with cell-free and cell-associated marek's disease virus. 19734123370
serological relationships among herpesviruses: cross-reaction between marek's disease virus and pseudorabies virus as detected by immunogluorescence.marek's disease virus (mdv) and pseudorabies virus (prv) cross-reacted by fluorescent antibody test but not by gel diffusion, virus neutralization, or cross-protection tests. herpesvirus of turkeys cross-reacted with mdv but not with prv. other herpesviruses tested did not have cross-reactions.19724117951
cell surface antigen on quail cells infected with herpesvirus of turkey or marek's disease virus. 19724349460
detection of virus-associated antigen on membranes of cells productively infected with marek's disease herpesvirus. 19724333493
marek's disease herpesvirus: growth and detection in vivo and in vitro. 19724333637
structural proteins of marek's disease virus. 19724333738
eb virus in relation to tumours. 19724376155
oncogenic herpesvirus infections of animals. 19724376157
production of circulating and cell-bound interferon in chickens by type 1 and type 2 plaque-producing agents of the cal-1 strain of marek's disease herpesvirus and herpesvirus of turkeys. 19724335399
influence of maternal antibody on infection with virulent or attenuated marek's disease herpesvirus. 19724335611
comparison of cytopathic effects of a classical isolate of marek's disease virus in cell cultures of duck embryo fibroblasts and chicken kidney. 19724335828
precipitating antibody development in birds infected with marek's disease virus. 19724335832
control of marek's disease in the netherlands. i. isolation of an avirulent marek's disease virus (strain cvi 988) and its use in laboratory vaccination trials. 19724337307
control of marek's disease in the netherlands. ii. field trials on vaccination with an avirulent strain (cvi 988) of marek's disease virus. 19724337309
attenuated marek's disease herpesvirus: protection conferred on strains of chickens varying in genetic resistance. 19724337320
marek's disease herpesvirus particles in tissues from chickens free of precipitating antibodies. 19724337914
radial immunodiffusion: a simple and rapid method for detection of marek's disease antigen(s).a qualitative radial immunodiffusion technique is described which detects antigen(s) in feathers from live or dead chickens infected with marek's disease herpesvirus. antiserum, which is incorporated into a support medium, reacts with antigen(s) in the feather tip producing a radial precipitin ring. antigen(s) was detected in 93.3% of experimentally inoculated chickens 21 days postinoculation and in 100% of infected birds subsequently tested through 6 weeks. no antigen was detectable in the feat ...19724338006
observations on field trials with an experimental attenuated marek's disease virus vaccine. 19724339083
lack of pathogenicity of marek's disease virus and herpesvirus of turkeys in marmoset monkeys. 19724343475
some characteristics of the a antigen in marek's disease virus--infected cell cultures. 19724345660
the fine structure of marek's disease virus and herpesvirus of turkey in cell culture. 19724347435
efficiency of commercial air filters against marek's disease virus.in a series of 10 replicate trials with susceptible chickens as indicators of the presence of virus in the air, filter b(1) (dri pak, american air filter co.), which has a dust spot rating of 93 to 97%, and filter c (astrocel), with a dioctyl phathalate aerosol rating of over 99%, completely removed marek's disease virus (mdv) from highly contaminated air. however, air passed through filter b(2) (duracel), with a dust spot rating of 34 to 45%, remained infectious. thus, an air filter with a dust ...19725021970
viral interference of types 1 and 2 plaque-producing agents derived from cal-1 strain of marek's disease herpesvirus and turkey herpesvirus. 19725030950
isolation of an anaerobic mycoplasma from avian cell cultures and some of its effects on marek's disease virus. 19725038652
induction of deoxyribonucleic acid synthesis and the oncogenicity of marek's disease virus.leukocytes recovered from birds inoculated with an oncogenic strain of marek's disease virus synthesized deoxyribonucleic acid in vitro at a rate 7.9 times that of leukocytes from normal birds or birds inoculated with the nononcogenic herpesvirus of turkeys. a close relationship was observed between the level of in vitro deoxyribonucleic acid synthesis and in vivo tumor formation.19725073927
isolation of marek's disease virus in lebanon. 19725078480
course of infection in tissues of susceptible chickens after exposure to strains of marek's disease virus and turkey herpesvirus. 19724650200
growth characteristics of a herpesvirus of turkeys.the herpesvirus of turkeys remains associated with cells attached to the culture vessel throughout its growth cycle. the level of infectious centers is essentially constant between 24 and 48 hr when the culture medium is unchanged. thereafter, the number of infectious centers decreases. the cessation of virus synthesis is not due to insufficient numbers of uninfected cells or interferon production. herpesvirus of turkeys does not replicate at 22 c and is similar to other herpesviruses in its sen ...19724675446
effects of passive antibody on early pathogenesis of marek's disease.the effects of passive marek's disease virus (mdv) antibody were characterized in three experiments in which 1- or 2-day-old pdrc chickens were inoculated with cell-associated mdv. antibody acquired naturally from the dam, or injected prior to, or at the time of, virus inoculation, failed to prevent infection, but the incidence and severity of the acute necrotizing disease were reduced. also, the number of tissues with viral antigen (fluorescent antibody test) and the amount of antigen in positi ...19724569917
decrease of antibody response to mycoplasma synoviae in chickens infected with marek's disease herpesvirus. 19724627550
isolation and characterization of an isolate (hn) of marek's disease virus with low pathogenicity.a cytopathic agent was isolated and characterized as an isolate of marek's disease herpesvirus (mdhv) with low pathogenicity, and referred to as the hn isolate. this isolate of mdhv did not cause clinical marek's disease (md) or death in a highly susceptible line of chickens within 5 weeks after exposure. gross lesions of limited extent were noted in a few of the inoculated birds. microscopic nerve lesions in the inoculated and contact-infected birds were invariably minimal, closely resembling c ...19724627960
genetic resistance to marek's disease. delineation of the response of genetically resistant chickens to marek's disease virus infection. 19724628020
delayed hypersensitivity reactions in marek's disease virus-infected chickens. 19724628212
[survival of marek's disease virus in the dust]. 19724629681
[presence and survival of the marek's disease virus in dust]. 19724631027
the epizootiology of marek's disease: i. incidence of antibody, viraemia and marek's disease in six flocks.six flocks consisting of the female grandparent line of a well known broiler strain were studied in an effort to determine the important aetiological factors in marek's disease. each flock was hatched in the same hatchery but at intervals of six weeks. chicks of each flock were reared to between 8 and 9 weeks of age on a rearing site after which they were moved to a production site. mortality was recorded to house and pen in all flocks. in addition six pens of about 300 chickens on each of the p ...197218777367
pathogenicity and antigenicity of clones from strains of marek's disease virus and the herpesvirus of turkeys.virus was extracted by filtration from chicken embryo fibroblast cultures infected with the jm, high passage jm(jmhp), ga, and rpl39 strains of marek's disease virus (mdv) and from the herpesvirus of turkeys (hvt) and purified by cloning. the plaques produced by clones of hvt, jmhp, and other mdv strains differed in morphology from one another. clones of mdv varied greatly in pathogenicity for chickens, but jmhp and hvt were nonpathogenic. two pathogenic clones of jm virus and a clone of jmhp vi ...197116557968
in vitro cell association of marek's disease herpesvirus. 19715101852
isolation and identification of marek's disease herpesvirus by yolk-sac inoculation method. 19715102179
evaluation of the chicken immune response to marek's disease herpesvirus. 19715155564
pathogenetic and serologic studies of type 1 and type 2 plaque-producing agents derived rom cal-1 strain of marek's disease virus. 19714993528
effect of vaccination with herpesvirus of turkeys (hvt) on horizontal spread of marek's disease herpesvirus. 19714325826
further studies on the replication of marek's disease virus in the chicken and in cell culture. 19714328192
the effect of marek's disease virus on the erythrocyte content of chicken blood. 19714328662
influence of bursa of fabricius on infection and pathological response of chickens exposed to marek's disease herpesvirus. 19714329202
some characteristics of cell-free preparations of marek's disease virus. 19714329205
large-scale production of marek's disease virus. 19714329206
antibodies for marek's disease virus in sera from domestic chickens and wild fowl in kenya. 19714329207
an improved in vitro assay for cell-free marek's disease virus. brief report. 19714330260
herpesviral isolates related to marek's disease virus from chicken and turkey kidney cell cultures. 19714334004
influence of natural exposure on response to subsequent challenge with virulent marek's disease virus. 19714334074
the temporal relationship between vaccination with the herpesvirus of turkeys and challenge with virulent marek's disease virus. 19714334075
experiments on the mode of spreading of marek's disease virus. 19714334325
interactions between marek's disease herpesvirus and avian leucosis virus in tissue culture. 19714331996
immunisation against newcastle disease in the presence of marek's disease virus. 19714332079
ultrastructural studies of a herpesvirus of turkeys antigenically related to marek's disease virus. 19714322626
size and composition of marek's disease virus deoxyribonucleic acid.deoxyribonucleic acid (dna) extracted from purified nucleocapsids of marek's disease herpesvirus (mdv) was cosedimented with t4 and with herpes simplex virus (hsv) dna in neutral sucrose density gradients and with t4 dna in alkaline sucrose density gradients. these experiments indicated that the intact mdv dna had a sedimentation constant of 56s corresponding to a molecular weight of 1.2 x 10(8) daltons. in the alkaline gradients, the largest and most prominent band contains a dna sedimenting at ...19714101222
responses of cell cultures from various avian species to marek's disease virus and herpesvirus of turkeys. 19714107762
specificity of the humoral and pathological response to marek's disease virus. 19704322705
marek's disease herpesvirus: comparison of foci (macro) in infected duck embryo fibroblasts under agar medium with foci (micro) in chicken cells. 19704323091
evidence against embryo transmission of marek's disease virus. 19704323098
isolation from turkeys of a cell-associated herpesvirus antigenically related to marek's disease virus. 19704314928
studies on the epidemiology of marek's disease herpesvirus in broiler flocks. 19704316766
the influence of ultraviolet-inactivated sendai virus on marek's disease virus infection in tissue culture. 19704320685
lyophilization of cell-free marek's disease herpesvirus and a herpesvirus from turkeys.cell extracts of the jm and ga strains of marek's disease herpesvirus and the fc 126 strain of turkey herpesvirus were lyophilized with various stabilizers. much higher virus titers were obtained with stabilizer than without stabilizer. titers increased even further in the case of the marek's disease virus strains by the addition of a chelating agent, disodium ethylenediaminetetraacetate.19704320863
cell-free transmission and in vivo replication of marek's disease virus.marek's disease virus recovered from the feather follicle of infected chickens was found to be infectious for chickens in cell-free preparations. the virus replicated in epithelial cells of the germinative layer of the feather follicle epidermis, producing both intranuclear and round or diffuse cytoplasmic inclusion bodies in the infected cells. it was found at this site 2 weeks postinoculation and prior to the development of tumor or other gross lesions. in the nucleus, many naked and a few env ...19704191324
marek's disease herpesvirus in peripheral nerve lesions. 19704331641
combined fluorescent-antibody and electron microscopy study of marek's disease virus-infected cell culture.duck embryo fibroblast (def) and chicken embryo fibroblast (cef) cultures infected with marek's disease virus were studied by combined fluorescent antibody and electron microscopy techniques. in both def and cef cultures, cells containing immunofluorescent (if) antigen also contained herpesvirus particles; conversely, cells lacking this antigen lacked herpesvirus particles. two morphologically distinct if antigens were detected in the cytoplasm. (i) a granular antigen in the perinuclear region w ...19704909910
detection of marek's disease herpesvirus antigen by fluorescent and coating antibody. 19704987720
site of replication of marek's disease virus. 19705538356
attenuation of marek's disease virus and study of its properties in two different cell cultures. 197011515447
infectivity of marek's disease agent after different treatments used in vaccine production. 196910200110
localization of viral antigen in chickens infected with marek's disease herpesvirus. 19694310100
marek's disease herpesvirus: in vivo and in vitro infection of kidney cells of different genetic strains of chickens. 19694311861
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