Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| familiarity breeds contempt: kangaroos persistently avoid areas with experimentally deployed dingo scents. | whether or not animals habituate to repeated exposure to predator scents may depend upon whether there are predators associated with the cues. understanding the contexts of habituation is theoretically important and has profound implication for the application of predator-based herbivore deterrents. we repeatedly exposed a mixed mob of macropod marsupials to olfactory scents (urine, feces) from a sympatric predator (canis lupus dingo), along with a control (water). if these predator cues were al ... | 2010 | 20463952 |
| epidemiological survey of trichinellosis in wild boar (sus scrofa) and fox (vulpes vulpes) in a french insular region, corsica. | the mediterranean island of corsica was considered trichinella-free until 2004, when t. britovi larvae were discovered in domestic pigs at meat inspection. one red fox was also found infected the same year and in the same area than the infected pigs. this last finding highlighted the presence of trichinellosis in corsican wildlife. a trichinella survey was thus performed in wild boar (sus scrofa) and fox (vulpes vulpes), the two large wild species present on the island, to determine prevalence o ... | 2010 | 20471753 |
| defibrillation delivered during the upstroke phase of manual chest compression improves shock success. | the current standard of manual chest compression during cardiopulmonary resuscitation requires pauses for rhythm analysis and shock delivery. however, interruptions of chest compression greatly decrease the likelihood of successful defibrillations, and significantly better outcomes are reported if this interruption is avoided. we therefore undertook a prospective randomized controlled animal study in an electrically induced ventricular fibrillation pig model to assess the effects of timing of de ... | 2010 | 20042857 |
| prevalence of hepatitis e virus-specific antibodies in sera of german domestic pigs estimated by using different assays. | hepatitis e virus is the causative agent of an acute hepatitis in humans. in industrialized countries, autochthonous hepatitis e cases in the past were mainly of undetermined origin, whereupon nowadays some cases may be linked to zoonotic transmission of hev from pigs and wild boars. in contrast to several european countries the hev status of german domestic pigs and a possible risk of transmission are unknown so far. here, a novel peptide-based elisa was used to detect hev-specific antibodies i ... | 2010 | 20045268 |
| development of an ultra-high-pressure liquid chromatography-tandem mass spectrometry multi-residue sulfonamide method and its application to water, manure slurry, and soils from swine rearing facilities. | an analytical method was developed using ultra-high-pressure liquid chromatography-triple quadrupole-tandem mass spectrometry (uhplc-tq-ms/ms) to simultaneously analyze 14 sulfonamides (sa) in 6 min. despite the rapidity of the assay the system was properly re-equilibrated in this time. no carryover was observed even after high analyte concentrations. the instrumental detection limit based on signal-to-noise ratio (s/n)>3, was below 1 pg/microl (5 pg on column) for all sas except sulfachloropyri ... | 2010 | 20047751 |
| molecular characterisation of african swine fever viruses from nigeria (2003-2006) recovers multiple virus variants and reaffirms cvr epidemiological utility. | samples collected from wild and domestic suids in nigeria, over a 3-year period (2003-2006), were evaluated for african swine fever (asf) virus genome presence by targeting three discrete genome regions, namely the 478-bp c-terminal p72 gene region advocated for genotype assignment, a 780-bp region spanning the 5'-ends of the pb125r and pb646l (p72) genes and the hypervariable central variable region (cvr) encoded within the 9rl orf (pb602l). asf virus (asfv) presence was confirmed in 23 of the ... | 2010 | 20052526 |
| seasonal effect on sperm messenger rna profile of domestic swine (sus scrofa). | seasonal infertility is a well-known problem in the modern swine (sus scrofa) industry. the molecular mechanisms responsible for thermal effects on spermatogenesis are, however, just beginning to be elucidated. the existence of specific messenger rna (mrna) remnants contained within freshly ejaculated sperm has been identified in several species. investigators have obtained differential rna profiles of infertile men compared with fertile individuals; however, there are limited to the probes, whi ... | 2010 | 20056359 |
| effects of oxygen tension and follicle cells on maturation and fertilization of porcine oocytes during in vitro culture in follicular fluid. | the objective was to investigate the effects of oxygen tension and follicle cells (fcs) during in vitro maturation of porcine oocytes in only porcine (sus scrofa domesticus) follicular fluid (pff), using static and non-static (rotating) culture systems, on the nuclear maturation and subsequent in vitro fertilization of the oocytes. in the first experiment, cumulus-oocyte complexes (cocs) were matured for 48 h in pff supplemented with (+) or without (-) fcs (5.2x10(6) cells/ml), using the static ... | 2010 | 20060577 |
| serological, pathological and polymerase chain reaction studies on mycoplasma hyopneumoniae infection in the wild boar. | there are evidences that wild boar and domestic pig populations share the vulnerability to certain pathogens and, in consequence, the risk of pathogen transmission. based on serological evidences, it is known that mycoplasma hyopneumoniae (mhyo) is able to infect the wild boar. however, if this infection causes lesions and disease in this species is still unknown. the objectives of the present study were to assess the seroprevalence to mhyo, as well as the rates of detection of mhyo (by nested p ... | 2010 | 20060659 |
| comparing the demonstration of freedom from trichinella infection of domestic pigs by traditional and risk-based surveillance. | traditionally, the routine artificial digestion test is applied to assess the presence of trichinella larvae in pigs. however, this diagnostic method has a low sensitivity compared to serological tests. the results from artificial digestion tests in switzerland were evaluated over a time period of 15 years to determine by when freedom from infection based on these data could be confirmed. freedom was defined as a 95% probability that the prevalence of infection was below 0.0001%. freedom was dem ... | 2010 | 20067658 |
| preliminary studies into the characterization of chemical markers of decomposition for geoforensics. | in this paper, we report the results of our preliminary studies into chemical characterization of the fluids produced during decomposition in the absence of a soil matrix. pig (sus domestica) carcasses were used to model the human decomposition process in two separate locations, western australia (perth) and canada (oshawa). analysis involved simple dilution and filtration of the decomposition fluids followed by gas chromatography-mass spectrometry. several previously unreported compounds were d ... | 2010 | 20070470 |
| survival and neurological outcomes after nasopharyngeal cooling or peripheral vein cold saline infusion initiated during cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest. | we have previously demonstrated that nasopharyngeal cooling initiated during cardiopulmonary resuscitation improves the success of resuscitation. in this study, we compared the effects of nasopharyngeal cooling with cold saline infusion initiated during cardiopulmonary resuscitation on resuscitation outcome in a porcine model of prolonged cardiac arrest. we hypothesized that nasopharyngeal cooling initiated during cardiopulmonary resuscitation would yield better resuscitation outcome when compar ... | 2010 | 20081534 |
| tissue distribution of polybrominated diphenyl ethers (pbdes) in captive domestic pigs, sus scrofa, from a village near an electronic waste recycling site in south china. | the dominant part of pbdes residue in pig tissues was bde-47 accounted for 48.2% approximately 66.9%, followed by bde-99 from 15.9% to 24.2%. when the data were on lipid weight basis, the summation operatorpbdes concentrations in tissues of individual pig showed the same order of liver > muscle, intestine > fat. principal component analysis and pbde congener mean concentration ratios of muscle versus liver (m/l), fat versus liver (f/l) and intestine versus liver (i/l) showed the higher accumulat ... | 2010 | 20091151 |
| ex vivo skin infection model. | over the past decade, the emergence of bacterial strains resistant to conventional antibiotics has necessitated the discovery and development of new antimicrobial therapies. this chapter describes a skin infection model that is based on the use of excised skin derived from the domestic pig. the model conditions mimic the environment of human skin and efficiently support the growth of clinically relevant bacterial and fungal species, thus making it useful for evaluating the activity of antimicrob ... | 2010 | 20094875 |
| spatial and temporal expression of spermadhesin genes in reproductive tracts of male and female pigs and ejaculated sperm. | spermadhesins, a novel protein family identified in the reproductive tract of ungulates, have important roles in reproduction. in this study, the expression of pig (sus domesticus) spermadhesion genes in seminal vesicles, prostate, and bulbourethral glands from birth to sexual maturity and the spatial expression in adult male and female genital tracts and ejaculated sperm of meishan pigs were evaluated by reverse transcription-polymerase chain reaction (rt-pcr). in general, all spermadhesin gene ... | 2010 | 20102779 |
| developmental ability of miniature pig embryos cloned with mesenchymal stem cells. | the present study compared the developmental ability of miniature pig embryos cloned with fetal fibroblasts (ffs), bone marrow-derived mesenchymal stem cells (mscs) and differentiated (osteocytes, adipocytes and chondrocytes) mscs. mscs were isolated from an approximately 1-month-old female miniature pig (t-type, pwg micro-pig((r)), pwg genetics korea). mscs were differentiated into osteocytes, adipocytes and chondrocytes under controlled conditions and characterized by cell surface antigen prof ... | 2010 | 20103985 |
| functional and comparative evaluation of flexible monopolar endoscopic scissors. | the continued success of natural orifice translumenal endoscopic procedures requires reliable, accurate tissue dissection and suture cutting. this study aimed to evaluate a flexible endoscopic scissors prototype. | 2010 | 20108151 |
| discriminating the effect of accelerated compression from accelerated decompression during high-impulse cpr in a porcine model of cardiac arrest. | piston based mechanical chest compression devices deliver compressions and decompressions in an accelerated pattern, resulting in superior haemodynamics compared to manual compression in animal studies. the present animal study compares haemodynamics during two different hybrid compression patterns to a standard compression pattern resembling that of modern mechanical chest compression devices. | 2010 | 20122780 |
| heterogeneity in spike protein genes of porcine epidemic diarrhea viruses isolated in korea. | porcine epidemic diarrhea virus (pedv) has plagued the domestic swine industry in korea causing significant economic impacts on pig production nationwide. in the present study, we determined the complete nucleotide sequences of the spike (s) glycoprotein genes of seven korean pedv isolates. the entire s genes of all isolates were found to be nine nucleotides longer in length than other pedv reference strains. this size difference was due to the combined presence of notable 15 bp insertion and 6 ... | 2010 | 20132850 |
| the influence of penetrative trauma on the rate of decomposition. | an understanding of the factors affecting decomposition is important for the accurate estimation of postmortem interval. an experimental study on the influence of penetrating trauma on decomposition rate was carried out using the domestic pig, sus scrofa. the results of this study were: (i) diptera were preferentially attracted to and oviposited at natural orifices. trauma sites were not preferentially selected for oviposition; (ii) no differences between trauma and non-trauma groups were found ... | 2010 | 20141561 |
| refinement of pig retroperfusion technique: global retroperfusion with ligation of the azygos connection preserves hemodynamic function in an acute infarction model in pigs (sus scrofa domestica). | in ischemic hearts, venous retroperfusion is a potential myocardial revascularization strategy. this study aimed to refine the technical and functional aspects of a pig model of acute myocardial infarction and retroperfusion with respect to the azygos connection. global retroperfusion after ligation of the ramus interventricularis paraconalis (equivalent to the left anterior descending artery in humans) was performed in 16 landrace pigs (sus scrofa domestica). coronary sinus perfusion was perfor ... | 2010 | 20158947 |
| nanofiber micro-dispersed oxidized cellulose as a carrier for topical antimicrobials: first experience. | micro-dispersed oxidized cellulose, already used for hemostasis, might be helpful for introduction of an antimicrobial drug. | 2010 | 20163259 |
| [the influence of hypothermia therapy on enzymology and pathology of lung after cardiac arrest]. | to study the effect of hypothermia on pro-inflammatory mediators in serum, the enzymology and pathology of lung tissue. | 2010 | 20170611 |
| a novel double-endoloop technique for natural orifice transluminal endoscopic surgery gastric access site closure. | effective and safe access site closure is critical for clinical application of natural orifice transluminal endoscopic surgery. | 2010 | 20170912 |
| human perception of vocalizations of domestic piglets and modulation by experience with domestic pigs (sus scrofa). | interspecific communication between humans and pets is possible through vocal cues. we studied how humans with differing experience with domestic pigs (sus scrofa) interpret pig vocalizations. forty-eight ethologists studying pigs, 31 pig-caretakers and 54 naive students evaluated the emotional intensity and valence (negative/positive) of recordings from two negative (castration, isolation) and two positive (reunion with the sow, postsuckling) contexts. they also identified the context in which ... | 2010 | 20175599 |
| reduction of odorants in swine manure by carbohydrate and bacterial amendments. | malodors from pig manure storage pits are a problem lacking a cost-efficient solution particularly for small pig (sus domestica) farms. the objective of this study was to reduce emissions of noxious odorants by changing the conditions in the pig manure to favor an altered microbial community. sugars (maltose, lactose, and saccharose), carbohydrate-rich waste (maltose syrup and wheat flour), and bacterial amendments (lactobacillus plantarum and l. amylophilus) were tested for their effect on manu ... | 2010 | 20176840 |
| artificial selection of the melanocortin receptor 1 gene in chinese domestic pigs during domestication. | black coat colour is common in chinese indigenous domestic pigs, but not among their wild ancestors, and it is thus presumed to be a 'domestication trait.' to determine whether artificial interference contributes to morphological diversification, we examined nucleotide variation from 157 chinese domestic pigs and 40 wild boars in the melanocortin receptor 1 (mc1r) gene, which has a key role in the coat pigmentation of sus scrofa. compared with a pseudogene gpip, our results showed that the joint ... | 2010 | 20179735 |
| a trucut biopsy needle for bipolar radiofrequency ablation of needle tract: a proof-of-concept experiment. | to develop a trucut biopsy needle featuring two electrodes that allow for bipolar radiofrequency (rf) coagulation of the puncture tract. | 2010 | 20179938 |
| peritoneal inflammation in pigs is associated with early mitochondrial dysfunction in liver and kidney. | the objective of this study was to investigate early effects of peritoneal inflammation on the mitochondrial function in the vital organs, liver and kidney, and their relation to inflammatory and oxidative stress mediators. the study was performed on 14 domestic pigs. peritoneal inflammation was induced in anesthetized pigs after a midline laparotomy by autologous feces. fluid resuscitation maintained a map above 60 mmhg. animals were sacrificed 12 h later, and tissue samples were obtained to de ... | 2010 | 20180005 |
| interplay between ovine bone marrow stromal cell antigen 2/tetherin and endogenous retroviruses. | endogenous betaretroviruses (enjsrvs) of sheep are expressed abundantly in the female reproductive tract and play a crucial role in conceptus development and placental morphogenesis. interestingly, the colonization of the sheep genome by enjsrvs is likely still ongoing. during early pregnancy, enjsrv expression correlates with the production of tau interferon (ifnt), a type i ifn, by the developing conceptus. ifnt is the pregnancy recognition signal in ruminants and possesses potent antiviral ac ... | 2010 | 20181686 |
| rapid and selective enzymatic debridement of porcine comb burns with bromelain-derived debrase: acute-phase preservation of noninjured tissue and zone of stasis. | deep burns are associated with the formation of an eschar, which delays healing and increases the risk of infection. surgical debridement of the eschar is, at present, the fastest means to achieve an eschar-free bed, but the process can not differentiate between the viable tissue and the eschar and follow the minute irregularities of the interface between the two. we evaluated the efficacy and selectivity of a novel enzymatic bromelain-based debriding agent, debrase gel dressing (debrase), in a ... | 2010 | 20182376 |
| comparison of articular cartilage repair by autologous chondrocytes with and without in vitro cultivation. | autologous chondrocyte implantation usually requires in vitro cell expansion before implantation. we compared the efficacy of cartilage regeneration by in vitro-expanded chondrocytes at high density and freshly harvested chondrocytes at low density. | 2010 | 20187869 |
| seroprevalence and risk factors associated with toxoplasma gondii infection in pig farms from catalonia, north-eastern spain. | seroprevalence and associated risk factors for toxoplasma gondii infection in pigs were analyzed in 1202 sera samples, including sows and pigs of three, seven, 11, 15 and 20 weeks of age, from 23 farms in catalonia, north-eastern spain. antibodies were tested by the modified agglutination test (mat) at titers > or =1:25. antibodies to t. gondii were found in 228 samples (19.0%; 95% ci: 16.8-21.2). the individual prevalence in animals higher than 7 weeks of age was 22.8% (174/762; 95% ci: 16.6-29 ... | 2010 | 20189210 |
| the effect of posterior distraction on vertebral growth in immature pigs: an experimental simulation of growing rod technique. | experimental study. | 2010 | 20195208 |
| blood meal analysis to identify reservoir hosts for amblyomma americanum ticks. | efforts to identify wildlife reservoirs for tick-borne pathogens are frequently limited by poor understanding of tick-host interactions and potentially transient infectivity of hosts under natural conditions. to identify reservoir hosts for lone star tick (amblyomma americanum)-associated pathogens, we used a novel technology. in field-collected ticks, we used pcr to amplify a portion of the 18s rrna gene in remnant blood meal dna. reverse line blot hybridization with host-specific probes was th ... | 2010 | 20202418 |
| tame affairs: domesticated transposase and domestic pigs. | 2010 | 20203696 | |
| spatial distribution and risk factors of brucellosis in iberian wild ungulates. | the role of wildlife as a brucellosis reservoir for humans and domestic livestock remains to be properly established. the aim of this work was to determine the aetiology, apparent prevalence, spatial distribution and risk factors for brucellosis transmission in several iberian wild ungulates. | 2010 | 20205703 |
| evaluation of a hemostatic sponge (tachosil) for sealing of the renal collecting system in a porcine laparoscopic partial nephrectomy survival model. | the objective of this study was to evaluate the efficacy of tachosil (nycomed uk, oxford, buckinghamshire, uk), a hemostatic sponge, to seal major collecting system injuries (in addition to providing an adjunct to hemostasis) after partial nephrectomy in a porcine chronic survival model. | 2010 | 20218894 |
| impact of tube current in the quantitative assessment of acute reperfused myocardial infarction with 64-slice delayed-enhancement ct: a porcine model. | this study evaluated the impact of tube current (mas) in delayed-enhancement computed tomography (ct) imaging for assessing acute reperfused myocardial infarction in a porcine model. | 2010 | 20221710 |
| deciphering modifications in swine cardiac troponin i by top-down high-resolution tandem mass spectrometry. | cardiac troponin i (ctni) is an important regulatory protein in cardiac muscle, and its modification represents a key mechanism in the regulation of cardiac muscle contraction and relaxation. ctni is often referred to as the "gold-standard" serum biomarker for diagnosing patients with acute cardiac injury since it is unique to the heart and released into the circulation following necrotic death of cardiac tissue. the swine (sus scrofa) heart model is extremely valuable for cardiovascular researc ... | 2010 | 20223681 |
| ischemia as a possible effect of increased intra-abdominal pressure on central nervous system cytokines, lactate and perfusion pressures. | the aims of our study were to evaluate the impact of increased intra-abdominal pressure (iap) on central nervous system (cns) cytokines (interleukin 6 and tumor necrosis factor), lactate and perfusion pressures, testing the hypothesis that intra-abdominal hypertension (iah) may possibly lead to cns ischemia. | 2010 | 20230612 |
| mammalian limb loading and chondral modeling during ontogeny. | the adaptive growth response of cartilage, or chondral modeling, can result in changes in joint and limb proportions during ontogeny and ultimately contribute to the adult form. despite hamrick's (1999) reevaluation of the mechanisms of chondral modeling, the process of chondral modeling remains poorly studied in animal models. here, we characterize the macro- and microanatomical responses of the femoral growth plate, articular cartilage, and bone in 15 juvenile sus scrofa domestica subjected to ... | 2010 | 20235322 |
| mutations in the ns1 c-terminal tail do not enhance replication or virulence of the 2009 pandemic h1n1 influenza a virus. | the 'classical' swine h1n1 influenza a virus lineage was established after the devastating 1918 human pandemic virus entered domestic pig herds. a descendent of this lineage recently re-emerged in humans as the 2009 pandemic h1n1 virus. adaptation in pigs has led to several changes in the multifunctional viral ns1 protein as compared with the parental 1918 virus, most notably a k217e substitution that abolishes binding to host crk/crkl signalling adapters, and an 11 aa c-terminal truncation. usi ... | 2010 | 20237225 |
| comparison between locking and non-locking plates for fixation of metacarpal fractures in an animal model. | the use of locking plates increases the primary load to failure, thereby reducing the rate of implant-related failure. the good clinical and biomechanical results of locking plates in long bones might be applicable to treatment of metacarpal fractures. the purpose of this study was to determine strength and stiffness of locking plates in a metacarpal fracture model with mono- and bicortical screw fixation in comparison to non-locking plate mono- and bicortical screw fixation, with both types of ... | 2010 | 20299161 |
| patterns of gene expression in swine macrophages infected with classical swine fever virus detected by microarray. | infection of domestic swine with highly virulent, classical swine fever virus (csfv) strain brescia, causes lethal disease in all infected animals. however, the molecular mechanisms involved in modulating the host cellular processes and evasion of the immune response have not been clearly established. to gain insight into, the early host response to csfv, we analyzed the pattern of gene expression in infected swine macrophages, using custom designed swine microarrays. macrophages, the target cel ... | 2010 | 20302897 |
| treatment with bioartificial liver improves lung injury in a swine model of partial hepatectomy and ischemia/reperfusion. | hepatic ischemia/reperfusion injury can lead to remote lung injury by inducing oxidative stress and inflammation. this study aims to investigate whether support of liver function with a bioartificial liver can attenuate remote lung injury after extended hepatectomy. | 2010 | 20306437 |
| [haemorrhagic septicaemia in a pig caused by extraintestinal pathogenic escherichia coli (expec) as a differential diagnosis in classical swine fever--case report and review of the literature]. | domestic pig herds in some regions of germany are permanently threatened by classical swine fever. in the case of suspicion, a series of infectious and non infectious causes has to be excluded. the present paper describes a case of escherichia coli septicaemia, with clinical and pathological symptoms that could not be differentiated from european or african swine fever. the e. coli strain could not be classified by standard serotyping. virulence factors common for etec (enterotoxic e. coli) or e ... | 2010 | 20329644 |
| a gel-free approach in vascular smooth muscle cell proteome: perspectives for a better insight into activation. | abstract: | 2010 | 20334645 |
| [radiofrequency ablation as a palliative therapy option in ent tumors: in vivo and in vitro testing]. | high frequency thermotherapy (hftt) is an established palliative therapy for hepatic malignancies. an in vivo and in vitro trial examined the preconditions for the application of hftt with liquid-cooled wet electrodes for minimally invasive palliation of head and neck tumors. | 2010 | 20336271 |
| the optimal phasic relationship between synchronized shock and mechanical chest compressions. | pauses for shock delivery in chest compressions are detrimental to the success of resuscitation and may be eliminated with the use of mechanical chest compressors. however, the optimal phasic relationship between mechanical chest compression and defibrillation is still unknown. we therefore undertook a study to assess the effects of timing of defibrillation in the mechanical chest compression cycle on the defibrillation threshold (dft) using a porcine model of cardiac arrest. | 2010 | 20346567 |
| qualitative and quantitative distribution of pcv2 in wild boars and domestic pigs in germany. | porcine circovirus 2 (pcv2), the causative agent of postweaning multisystemic wasting syndrome (pmws), has been detected in north american and european wild boars at prevalences arguing for high circulation rates among populations. systematic data on the qualitative distribution of pcv2 infections and on pcvd (pcv2 diseases) in wild boars are rare, however, and quantitative data about viral loads are missing. to be able to judge the pcv2/pcvd situation in wild boars, evaluation of the nationwide ... | 2010 | 20346600 |
| glucagon-like peptide-1 (glp-1) attenuates post-resuscitation myocardial microcirculatory dysfunction. | post-resuscitation syndrome leads to death in approximately 2 out of every 3 successfully resuscitated victims, and myocardial microcirculatory dysfunction is a major component of this syndrome. the aim of this study was to determine if glucagon-like peptide-1 (glp-1) improves post-resuscitation myocardial microcirculatory function. | 2010 | 20347207 |
| calcium-dependent signalling is essential during collateral growth in the pig hind limb-ischemia model. | we investigated the effect of pharmacological activation of the ca(2+)-channel transient receptor potential cation channel, subfamily v, member 4 (trpv4) on collateral growth in a pig hind limb-ischemia model thereby identifying subcellular mechanisms. domestic pigs received femoral artery ligature and were randomly assigned to one of the following groups (each n=6): (1) 4alpha-phorbol 12,13-didecanoate (4alphapdd) treatment; (2) treatment with an arterio-venous shunt (av-shunt) distal to the oc ... | 2010 | 20363225 |
| studying phenotypic evolution in domestic animals: a walk in the footsteps of charles darwin. | charles darwin used domesticated plants and animals as proof of principle for his theory on phenotypic evolution by means of natural selection. inspired by darwin's work, we developed an intercross between the wild boar and domestic pigs to study the genetic basis for phenotypic changes during domestication. the difference in coat color is controlled by two major loci. dominant white color is due to two consecutive mutations in the kit gene: a 450-kb duplication and a splice mutation. black spot ... | 2010 | 20375320 |
| heterogeneous memory in restitution of action potential duration in pig ventricles. | restitution of action potential duration and memory importantly affect electrical stability in ventricles. studies have reported heterogeneous restitution among different regions of the ventricles. however, existence of heterogeneity in memory is not as well investigated. | 2010 | 20378123 |
| a novel approach for reinforcing the pancreatic remnant in laparoscopic distal pancreatectomy: an experimental study on a porcine model. | the major postoperative complication after open and laparoscopic distal pancreatectomy is pancreatic fistula. different operative techniques have been tested to minimize this unpleasant complication. we evaluated a new technique for pancreatic stump reinforcement with synthetic glue after laparoscopic distal pancreatectomy. ten female domestic pigs were divided into 2 groups; in group a (n=5), the pancreas was transected using an endogia stapler, whereas in group b (n=5), the pancreas was transe ... | 2010 | 20393319 |
| development and validation of a sensitive hplc method for the quantification of hi-6 in guinea pig plasma and evaluated in domestic swine. | a rapid and small volume assay to quantify hi-6 in plasma was developed to further the development and licensing of an intravenous formulation of hi-6. the objective of this method was to develop a sensitive and rapid assay that clearly resolved hi-6 and an internal standard in saline and plasma matrices. a fully validated method using ion-pair hplc and 2-pam as the internal standard fulfilled these requirements. small plasma samples of 35 microl were extracted using acidification, filtration an ... | 2010 | 20395179 |
| relative distribution of drugs in decomposed skeletal tissue. | skeletal tissues from a domestic pig exposed to amitriptyline, diazepam, and pentobarbital were analyzed to determine the relative distribution of these drugs in bone. following drug exposure and euthanasia, remains were allowed to decompose outdoors to complete skeletonization between summer 2007 and fall 2009. remains were recovered and separated according to bone type. twelve different bone types were pulverized and sampled in triplicate. each bone sample underwent methanolic extraction (96 h ... | 2010 | 21819797 |
| orthodontic tooth movement into jaw regions treated with synthetic bone substitute. | orthodontic tooth movement is fraught with risks and complications. root resorption is the most frequent and important outcome which may arise due to inappropriate force magnitude or tooth movement into dense or altered bone. this study was aimed to demonstrate histologic changes in tooth roots following movement into a jaw region treated with synthetic bone substitute. another objective was to evaluate the method of experimental tooth movement using an animal model. | 2010 | 21469267 |
| distribution of myocardial bridges in domestic pig. | localisation and morphology of myocardial bridges in the heart of domestic pig remain an open issue. since these structures significantly influence haemodynamics in the coronary arteries, their occurance may lead to numerous pathologies. in the examined group of 150 domestic pig's hearts, myocardial bridges were diagnosed in 47.3% of the material, mostly in males. in majority of cases the bridges were present above the posterior interventricular branch of the right coronary artery, less often ab ... | 2010 | 21370748 |
| morphological changes and immunohistochemical expression of rage and its ligands in the sciatic nerve of hyperglycemic pig (sus scrofa). | the aim of our project was to study the effect of streptozotocin (stz)-induced hyperglycemia on sciatic nerve morphology, blood plasma markers and immunohistochemical expression of rage (the receptor for advanced glycation end-products), and its ligands-s100b and carboxymethyl lysine (cml)-advanced glycation endproduct (age) in the laboratory pig. six months after stz-injections, blood plasma measurements, morphometric analysis of sciatic nerve fiber density, immunofluorescent distribution of po ... | 2010 | 21852897 |
| a comparative assessment of zootherapeutic remedies from selected areas in albania, italy, spain and nepal. | zootherapy is the treatment of human ailments with remedies derived from animals and their products. despite its prevalence in traditional medical practices worldwide, research on this phenomenon has often been neglected in comparison to medicinal plant research. interviews regarding zootherapeutic traditions were conducted with informants from albania, italy, nepal and spain. we identified 80 species used in zootherapeutic remedies, representing 4 phyla in the animal kingdom: annelida, arthropo ... | 2010 | 21625340 |
| application of gis in epizootiological surveillance of swine trichinellosis in one endemic district in serbia. | application of new tools for epizootiological investigations in veterinary medicine, such as geographical information systems (gis), offers a new approach and possibilities for the eradication or control of infectious diseases. gis is particularly useful for research conducted in small areas strongly impacted by man. trichinellosis is a world-wide zoonosis, which is endemic in some european countries, balkan district and serbia in particular. there are very few data on gis application in the fie ... | 2010 | 21275245 |
| evaluation of genetic variability in the collared peccary pecari tajacu and the white-lipped peccary tayassu pecari by microsatellite markers. | in this study, the microsatellite technique was used to evaluate the genetic variability in populations of collared and white-lipped peccaries kept in captivity. six primers developed for domestic pigs were used and amplified in both species. they revealed the presence of five polymorphic loci and one monomorphic locus. the polymorphic loci included 4 of the 16 alleles in collared peccaries, and 3 of the 10 alleles in the white-lipped peccaries. polymorphic information content (pic) in both spec ... | 2010 | 21637606 |
| feasibility and safety of endoscopic transesophageal access and closure using a maryland dissector and a self-expanding metal stent. | background: secure access and reliable closure is paramount in the setting of transesophageal mediastinal endoscopic surgery. the purpose of this study was to develop a secure transesophageal access technique and to evaluate the feasibility, safety, and efficacy of a novel covered, self-expanding, retractable stent for closure of 15-mm esophageal defects. methods: fifteen-millimeter esophagotomies were created in 18 domestic pigs using needle knife puncture and balloon dilatation or a blunt diss ... | 2010 | 21136086 |
| porcine models for the metabolic syndrome, digestive and bone disorders: a general overview. | the aim of this review article is to provide an overview of the role of pigs as a biomedical model for humans. the usefulness and limitations of porcine models have been discussed in terms of metabolic, cardiovascular, digestive and bone diseases in humans. domestic pigs and minipigs are the main categories of pigs used as biomedical models. one drawback of minipigs is that they are in short supply and expensive compared with domestic pigs, which in contrast cost more to house, feed and medicate ... | 2010 | 22444262 |
| identification of mitochondrial markers for genetic traceability of european wild boars and iberian and duroc pigs. | iberian pigs and wild boars are the source of highly priced meat and dry-cured products. iberian maternal origin is mandatory for labeled iberian products, making necessary the authentication of their maternal breed origin. discrimination between wild and domestic pig maternal origin may be useful to distinguish labeled wild boar meat obtained from hunting or farming. in order to detect useful polymorphisms to trace iberian, duroc and wild boar maternal lineages, we herein investigated the compl ... | 2009 | 22444897 |
| epicardial ablation on the beating heart: limited efficacy of a novel, cooled radiofrequency ablation device. | objective: to perform a minimally invasive procedure for atrial fibrillation without cardiopulmonary bypass, it is necessary to create transmural lesions on the beating heart. although bipolar radiofrequency clamps can isolate the pulmonary veins, they have difficulty in performing any other left atrial lesions, particularly those of the traditional cox-maze procedure. this study examined the performance of an internally cooled, bipolar radiofrequency device designed for such an application. met ... | 2009 | 22323899 |
| comparative animal study on hard tissue integration and bone formation of different nobel biocare implants. | dental implantation aims at optimal and long-term hard tissue integration. beside primary stability, loading time and other factors, e.g. the surface of the endosteal part of the implant, is a matter of special importance. in this animal trial, hard tissue integration of two different implant types was studied using radiological, histological and histomorphometric analysis. two different implants with an oxidized surface (tiunite; nobel biocare ab, goteborg, sweden, nobelreplace tapered groovy 4 ... | 2009 | 20400804 |
| brucella suis infection in domestic pigs and wild boar in croatia. | between the years 2000 and 2004, 93,107 sera from 1,997 pig herds in 11 regions of croatia were tested for the presence of antibodies against brucellosis. positive results were observed in 67 herds from seven regions (mean individual prevalence: approximately 1%; herd prevalence: 3.4%). the herds from all but two of the infected farms were reared outdoors and thus almost certainly came into contact with wildlife. from 2003 to 2004, 424 sera, which were randomly collected from hunted wild boar (s ... | 2009 | 20462164 |
| sequential activation of ground pads reduces skin heating during radiofrequency ablation: initial in vivo porcine results. | radiofrequency (rf) ablation is a common treatment modality for inoperable liver cancer. skin burns below ground pads during rf ablations are increasingly prevalent, hindering the development of higher-power rf generators capable of creating larger ablation zones. | 2009 | 19963820 |
| african swine fever. | african swine fever (asf) is a devastating haemorrhagic fever of pigs that causes up to 100% mortality, for which there is no vaccine. it is caused by a unique dna virus that is maintained in an ancient cycle between warthogs and argasid ticks, making it the only known dna arbovirus. asf has a high potential for transboundary spread, and has twice been transported from africa to other continents--europe and subsequently the caribbean and brazil (1957, 1959) and the caucasus (2007). it is also a ... | 2009 | 19967933 |
| the genome sizes of megabats (chiroptera: pteropodidae) are remarkably constrained. | it has long been recognized that bats and birds contain less dna in their genomes than their non-flying relatives. it has been suggested that this relates to the high metabolic demands of powered flight, a notion that is supported by the fact that pterosaurs also appear to have exhibited small genomes. given the long-standing interest in this question, it is surprising that almost no data have been presented regarding genome size diversity among megabats (family pteropodidae). the present study ... | 2009 | 19324635 |
| effect of betaine supplementation on power performance and fatigue. | the purpose of this study was to examine the efficacy of 15 days of betaine supplementation on muscle endurance, power performance and rate of fatigue in active college-aged men. | 2009 | 19250531 |
| physiologic compliance in engineered small-diameter arterial constructs based on an elastomeric substrate. | compliance mismatch is a significant challenge to long-term patency in small-diameter bypass grafts because it causes intimal hyperplasia and ultimately graft occlusion. current engineered grafts are typically stiff with high burst pressure but low compliance and low elastin expression. we postulated that engineering small arteries on elastomeric scaffolds under dynamic mechanical stimulation would result in strong and compliant arterial constructs. this study compares properties of engineered a ... | 2009 | 19962188 |
| the risk of extrapolation in neuroanatomy: the case of the mammalian vomeronasal system. | the sense of smell plays a crucial role in mammalian social and sexual behaviour, identification of food, and detection of predators. nevertheless, mammals vary in their olfactory ability. one reason for this concerns the degree of development of their pars basalis rhinencephali, an anatomical feature that has been considered in classifying this group of animals as macrosmatic, microsmatic or anosmatic. in mammals, different structures are involved in detecting odours: the main olfactory system, ... | 2009 | 19949452 |
| comparative snp diversity among four eucalyptus species for genes from secondary metabolite biosynthetic pathways. | there is little information about the dna sequence variation within and between closely related plant species. the combination of re-sequencing technologies, large-scale dna pools and availability of reference gene sequences allowed the extensive characterisation of single nucleotide polymorphisms (snps) in genes of four biosynthetic pathways leading to the formation of ecologically relevant secondary metabolites in eucalyptus. with this approach the occurrence and patterns of snp variation for ... | 2009 | 19775472 |
| mouse x pig chimeric antibodies expressed in baculovirus retain the same properties of their parent antibodies. | the development of hybridoma and recombinant dna technologies has made it possible to use antibodies against cancer, autoimmune disorders, and infectious diseases in humans. these advances in therapy, as well as immunoprophylaxis, could also make it possible to use these technologies in agricultural species of economic importance such as pigs. porcine reproductive and respiratory syndrome virus (prrsv) is an arterivirus causing very important economic losses to the industry. passive transfer of ... | 2009 | 19301248 |
| molecular magnetic resonance imaging of myocardial perfusion with ep-3600, a collagen-specific contrast agent: initial feasibility study in a swine model. | cardiac magnetic resonance (mr) perfusion imaging during the first pass after intravenous administration of extracellular contrast agents is hampered by the spatial and temporal resolution achievable and by the artifacts seen in ultrafast mr imaging. furthermore, time-consuming quantitative data analysis is often added. the use of molecular mr imaging with a target-specific contrast agent with perfusion-dependent binding to myocardium may enable prolonged visualization of perfusion defects and t ... | 2009 | 19307474 |
| comparison of electrically induced flare response patterns in human and pig skin. | we compared the characteristics of neurogenic flare responses in human and pig skin to establish a translational research animal model. | 2009 | 19319479 |
| non-iterative variance component estimation in qtl analysis. | in variance component quantitative trait loci (qtl) analysis, a mixed model is used to detect the most likely chromosome position of a qtl. the putative qtl is included as a random effect and a method is needed to estimate the qtl variance. the standard estimation method used is an iterative method based on the restricted maximum likelihood (reml). in this paper, we present a novel non-iterative variance component estimation method. this method is based on henderson's method 3, but relaxes the c ... | 2009 | 19320767 |
| mitochondrial dna sequence variations in some italian wild boar populations. | in order to investigate the relationships between italian wild boar and major pig breeds, we studied the genetic variability of four wild boar populations in italy (arezzo, pisa, parma, bergamo) using a 533-bp fragment of the mitochondrial control region. sixty-nine wild boar samples were analysed, allowing the identification of 10 distinct haplotypes, which involve a total of 15 single nucleotide polymorphisms. phylogenetic and network analyses were performed also considering several sequences ... | 2009 | 19320773 |
| normal profiles for deciduous dental eruption in domestic piglets: effect of sow, litter, and piglet characteristics. | the deciduous dentition of the domestic pig is comprised of 28 teeth (2 x incisors 3/3, canine 1/1, premolars 3/3, molars 0/0). the timing and sequence of deciduous dental eruption were determined from oral exams on 233 yorkshire piglets from 0 to 5 wk of age. eruption occurred sooner in gilts for all molariform premolars (p(3), p(4), and p(4), p < 0.01) and first incisor, i(1) (p = 0.004). birth weight influenced eruption for all teeth except i(1) (i(1), p(3), p(3), p(4), and p(4); p < 0.01), w ... | 2009 | 19329477 |
| portal vein embolization with radiolabeled polyvinyl alcohol particles in a swine model: hepatic distribution and implications for pancreatic islet cell transplantation. | the distribution of radiolabeled polyvinyl alcohol microspheres (pvams) when infused into the portal vein of domestic swine was investigated, with the purpose of assessing implications for pancreatic islet cell transplantation. pvams measuring 100-300 microm (contour se) and labeled with (99m)tc were infused into the main portal vein of 12 swine, with intermittent portal venous pressure measurements. the infusion catheter was introduced antegradely via direct or indirect cannulation of the porta ... | 2009 | 19330373 |
| complex porcine model of atherosclerosis: induction of early coronary lesions after long-term hyperlipidemia without sustained hyperglycemia. | the incidence of coronary artery disease (cad) is still increasing in industrialized countries and it is even higher in diabetic patients. for experimental studies investigating the pathophysiology of cad, the use of an animal model comparable with the pathological situation in patients is crucial. | 2009 | 19340354 |
| evaluation of endoscopic-ultrasound-guided celiac ganglion irradiation with iodine-125 seeds: a pilot study in a porcine model. | implantation of iodine-125 ( (125)i) seeds under the guidance of endoscopic ultrasonography (eus) has been proved to be a safe alternative treatment option for advanced pancreatic cancer. the main purpose of this study was to evaluate the feasibility and safety of eus-guided radiation of the celiac ganglia with (125)i seeds in a porcine model. | 2009 | 19340740 |
| imaging sequences for intraoperative mr-guided laparoscopic liver resection in 1.0-t high field open mri. | the aim of this study was to identify suitable interactive (dynamic) magnetic resonance (mr) sequences for real-time mr-guided liver dissection in a 1.0-t high field open mri system. four dynamic sequences encompassing balanced steady state free precession (bssfp), t1w gradient echo (gre), t2w gre and t2w fast spin echo (fse) were analysed regarding the image quality, artefact susceptibility and the performance of snr and cnr. the t2w fse sequence (1.5 s/image) was considered superior because of ... | 2009 | 19350246 |
| percutaneous left ventricular assist in ischemic cardiac arrest. | ischemic cardiac arrest represents a challenge for optimal emergency revascularization therapy. a percutaneous left ventricular assist device (lvad) may be beneficial. | 2009 | 19242324 |
| epinephrine reduces cerebral perfusion during cardiopulmonary resuscitation. | epinephrine has been the primary drug for cardiopulmonary resuscitation (cpr) for more than a century. the therapeutic rationale was to restore threshold levels of myocardial and cerebral blood flows by its alpha1 (alpha1) and alpha2 (alpha2)-adrenergic agonist vasopressor actions. on the basis of coincidental observations on changes in microvascular flow in the cerebral cortex, we hypothesized that epinephrine selectively decreases microvascular flow. | 2009 | 19242339 |
| phase-contrast mri-based elastography technique detects early hypertensive changes in ex vivo porcine aortic wall. | to measure the elastic properties of ex vivo porcine aortas in control and hypertensive groups using a phase contrast magnetic resonance imaging (mri)-based elastography technique. | 2009 | 19243040 |
| a stochastic model to quantify the risk of introduction of classical swine fever virus through import of domestic and wild boars. | classical swine fever (csf) is a disease of pigs that imposes major hardship on the industry of infected regions. the recent history of csf epidemics suggests that animal movements remain the main source of csf virus (csfv) infection for susceptible populations in europe. this study presents an assessment of the risk of introducing csfv into spain through the importation of live susceptible animals. results suggest that, if prevailing conditions persist, introduction of csfv into spain is likely ... | 2009 | 19243649 |
| isolate designation and characterization of toxoplasma gondii isolates from pigs in the united states. | pigs are considered to be the most important meat source of toxoplasma gondii for humans in the united states. in the present study, 168 t. gondii isolates (designated tgpgus15-182) from various sources were genotyped using 10 polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) markers (sag1, sag2, sag3, btub, gra6, c22-8, c29-2, l358, pk1, and apico). genotyping data from an additional 14 isolates collected from t. gondii-infected pigs in maryland were included for ana ... | 2009 | 19245283 |
| the effects of fasting and general anesthesia on serum chemistries in kcg miniature pigs. | investigators are obligated to optimize the perioperative care of experimental animals, but little is known about the effects of anesthesia and surgery on serum chemistries in kcg pigs. the objective of this study was to examine the influence of fasting and surgery under general anesthesia on 27 serum chemistries in kcg miniature pigs to improve management. crossbred kcg minipigs were used at a mean of 12.3 mo of age (range, 8.6 to 14.9) and 33.4 kg of body weight (range, 24.0 to 40.2). serum ch ... | 2009 | 19245748 |
| effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism. | streptozotocin (stz) given intravenously destroys pancreatic beta cells and is widely used in animal models to mimic type 1 diabetes. the effects of stz on the clinical state of health and metabolism were studied in six high health certified domestic pigs weighing 19+/-1.3 kg at the start of the experiment. a single stz dose of 150 mg/kg of body weight successfully induced hyperglycaemia and alterations in amino acid metabolism. within 9 h after stz administration, the blood glucose values fell ... | 2009 | 19246503 |
| animal evolution during domestication: the domesticated fox as a model. | we review the evolution of domestic animals, emphasizing the effect of the earliest steps of domestication on its course. using the first domesticated species, the dog (canis familiaris), for illustration, we describe the evolutionary peculiarities during the historical domestication, such as the high level and wide range of diversity. we suggest that the process of earliest domestication via unconscious and later conscious selection of human-defined behavioral traits may accelerate phenotypic v ... | 2009 | 19260016 |
| cysticercosis of soft tissue. | cysticercosis is a systemic illness caused by dissemination of the larval form of the pork tapeworm, taenia solium. a high prevalence has been reported from the developing countries because of the co-existence of poor sanitary conditions and domestic pig raising. human cysticercosis occurs when eggs are ingested via faecal-oral transmission from a tapeworm host. the human then becomes an accidental intermediate host, with development of cysticerci within organs. cysticercosis is a preventable fa ... | 2009 | 19260577 |
| the association between central venous pressure, pneumoperitoneum, and venous carbon dioxide embolism in laparoscopic hepatectomy. | laparoscopic hepatectomy (lh) is increasingly used. however, the safety and outcomes of lh have yet to be elucidated. the risk of venous gas embolism is increased during liver parenchymal transection. this risk may be increased with positive pressure carbon dioxide (co(2)) pneumoperitoneum (pp). this may be exacerbated further when low central venous pressure (cvp) anesthesia is used to minimize hemorrhage during liver resection. | 2009 | 19266234 |
| giardia genotypes in pigs in western australia: prevalence and association with diarrhea. | little is known of the prevalence of giardia species and genotypes in pre- and post-weaned domestic pigs. in the present study, a total of 297 pig faecal samples were screened for the presence of giardia by pcr and genotyped. an overall prevalence of 31.1% (90/289) (25.8, 36.5 ci) was detected. giardia was detected in 17% (23/123) (11.8-25.6 ci) of pre-weaned piglet faecal samples and 41% (64/156) (33.3-48.7 ci) post-weaned faecal samples analysed. sequence analysis identified assemblage a and e ... | 2009 | 19271283 |
| comparison of two different paclitaxel-coated balloon catheters in the porcine coronary restenosis model. | drug-eluting balloon (deb) catheters coated with paclitaxel in a water-soluble matrix have shown beneficial effects in the treatment and prevention of restenosis in the porcine coronary overstretch model and in clinical trials. adherence of paclitaxel, same dose, on another recently introduced coated percutaneous coronary intervention (pci) catheter (dior) is mediated by a roughened balloon surface. only scarce experimental and clinical data has been published on the new coating method. the aim ... | 2009 | 19280084 |
| a family of splice variants of cstf-64 expressed in vertebrate nervous systems. | alternative splicing and polyadenylation are important mechanisms for creating the proteomic diversity necessary for the nervous system to fulfill its specialized functions. the contribution of alternative splicing to proteomic diversity in the nervous system has been well documented, whereas the role of alternative polyadenylation in this process is less well understood. since the cstf-64 polyadenylation protein is known to be an important regulator of tissue-specific polyadenylation, we examin ... | 2009 | 19284619 |