Publications

bartonella henselae-associated acute multifocal retinitis in a patient with acquired immunodeficiency syndrome.		1997	9355199
analysis of 36-kilodalton protein (papa) associated with the bacteriophage particle of bartonella henselae.	a library of bartonella henselae dna was screened with antibody raised to the bacteriophage particle associated with this organism. a clone was isolated that expresses a 36-kd protein (termed papa for particle-associated protein) when examined by immunoblot analysis using antibody raised to the particle. southern blot hybridization indicates that the gene is present on the bacterial chromosome and packaged into the 14-kb particle-associated dna. a papa-specific probe hybridized to multiple bands ...	1997	9364933
american academy of dermatology 1997 awards for young investigators in dermatology. pathogenesis of bartonella henselae in cutaneous and systemic disease.		1997	9366828
efficacy of enrofloxacin or doxycycline for treatment of bartonella henselae or bartonella clarridgeiae infection in cats.	enrofloxacin and doxycycline are antimicrobial agents used to treat bacterial diseases of cats. in vitro susceptibility data indicate that either drug should be effective against bartonella species. in vivo efficacies of these drugs for eradication of chronic bartonella henselae or bartonella clarridgeiae infections were examined in 18 experimentally infected cats and 25 naturally exposed cats treated with enrofloxacin (22.7 mg given orally [po] every 12 h [q12h] [14 days, n = 10; 28 days, n = 1 ...	1997	9371348
interaction of bartonella henselae with endothelial cells results in bacterial aggregation on the cell surface and the subsequent engulfment and internalisation of the bacterial aggregate by a unique structure, the invasome.	vascular colonisation by bartonella henselae may cause vaso-proliferative tumour growth with clumps of bacteria found in close association with proliferating endothelial cells. by using b. henselae-infected human umbilical vein endothelial cells as an in vitro model for endothelial colonisation, we report here on a novel mechanism of cellular invasion by bacteria. first, the leading lamella of endothelial cells establishes cellular contact to sedimented bacteria and mediates bacterial aggregatio ...	1997	9378764
[cat scratch disease. diagnostic and therapeutic considerations].		1997	9382360
distribution, diversity, and host specificity of bartonella in rodents from the southeastern united states.	a number of bartonella isolates were obtained from seven species of rodents sampled from 12 geographic sites representing the major biotic communities of the southeastern united states. bartonella were isolated from the blood of 42.2% of 279 tested rodents. the highest prevalence of infection typically occurred among the most commonly captured species in the rodent community. four phylogenetic groups, uniting 14 genotypic variants of bartonella, were identified by sequence analysis of the citrat ...	1997	9392599
bartonella-like erythrocyte inclusions in thrombotic thrombocytopenic purpura.		1997	9393349
possible role of lutzomyia maranonensis and lutzomyia robusta (diptera: psychodidae) as vectors of human bartonellosis in three provinces of region nor oriental del marañon, peru.		1997	9394538
[a case of cat scratch disease identified by an elevated bartonella henselae antibody level using enzyme immunoassay].	a 68-year-old male was admitted to our hospital because of fever and a 2-week history of inguinal adenomegaly. since he owned a cat, cat scratch disease was suspected. but it was necessary to distinguish cat scratch disease from lymphoma type adult t-cell leukemia because he showed a high level of antibody against htlv-1. an excisional biopsy of the inguinal node was performed. histopathologic examination revealed abscess-forming granulomatous lymphadenitis compatible with cat scratch disease. a ...	1997	9394562
inflammatory mass of the optic nerve head associated with systemic bartonella henselae infection.		1997	9400801
molecular epidemiology of bartonella infections in patients with bacillary angiomatosis-peliosis.	bacillary angiomatosis and bacillary peliosis are vascular proliferative manifestations of infection with species of the genus bartonella that occur predominantly in patients infected with the human immunodeficiency virus. two species, b. henselae and b. quintana, have been associated with bacillary angiomatosis, but culture and speciation are difficult, and there has been little systematic evaluation of the species-specific disease characteristics. we studied 49 patients seen over eight years w ...	1997	9407154
of cats, humans, and bartonella.		1997	9407161
comparison of the abilities of proteins from bartonella bacilliformis and bartonella henselae to deform red cell membranes and to bind to red cell ghost proteins.	infections in humans by bartonella bacilliformis, but not bartonella henselae, are characterized by invasion of red cells. supernatants of culture medium from b. bacilliformis and b. henselae each contain a protein which causes invagination of membranes of human red cells and formation of intracellular vacuoles. these two proteins are very similar in molecular mass, heat stability and mechanism of action. b. henselae does not bind to human red cells, but human red cell ghost membrane proteins we ...	1997	9418257
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 2-1997. a 38-year-old man with digital clubbing, low-grade fever, and a murmur.		1997	8988901
maintenance of broad-host-range incompatibility group p and group q plasmids and transposition of tn5 in bartonella henselae following conjugal plasmid transfer from escherichia coli.	the first demonstration of conjugal plasmid transfer from escherichia coli to bartonella henselae is reported. transconjugants bearing plasmids of incompatibility groups p (incp) and q (incq), expressing various resistance markers, were generated. tn5 transposons delivered on suicide plasmids by conjugation showed transpositional insertion into random chromosomal sites.	1997	8990308
redefining aids: towards a modification of the current aids case definition.	aids is defined by the occurrence of an opportunistic infection or tumor considered indicative of advanced infection with human immunodeficiency virus (hiv). even though recent modifications have improved the widely used aids case definition issued by the world health organization and the centers for disease control and prevention, the modified version has fallen short of generating a globally functional instrument for the surveillance of hiv-related infections. the clinical aids case definition ...	1997	8994765
the expanding spectrum of bartonella infections: i. bartonellosis and trench fever.		1997	9002093
experimental and natural infection with bartonella henselae in domestic cats.	domestic cats were experimentally infected with culture propagated bartonella henselae by intradermal (i.d.) and intravenous (i.v.) routes. cats were more efficiently infected by the i.d. (8/8 cats) than by the i.v. (2/16) route. bacteremia was detected 1-3 weeks following inoculation and lasted for most cats for 1-8 months. however, one naturally infected cat was observed for 24 months and was found to be cyclically bacteremic, with bacterial levels varying one hundred fold or more from one per ...	1997	9023040
bacillary angiomatosis: presentation of six patients, some with unusual features.	bacillary angiomatosis (ba) is an unusual systemic vascular proliferation seen predominantly in patients with the acquired immunodeficiency syndrome. these vascular lesions are probably due to infection with a bartonella species, most often b. henselae and, in some patients, b. quintana. ba is treatable and often curable, but without therapy, may be life-threatening. clinically, the lesions, when superficial, are said to often resemble pyogenic granulomas, appearing polypoid histologically with ...	1997	9039296
isolation of bartonella (rochalimaea) henselae: effects of methods of blood collection and handling.	bartonella (rochalimaea) henselae causes cat-scratch disease, bacillary angiomatosis, peliosis hepatis, and fever in humans. b. henselae can be difficult to culture axenically, and as many as 5 weeks may be required before colonies are visible. we compared how different methods of blood collection and handling affect isolation of this pathogen. blood specimens from b. henselae-infected cats were collected in both edta and isolator blood-lysis tubes and were subsequently plated onto rabbit blood- ...	1997	9041385
detection and identification of two bartonella henselae variants in domestic cats in germany.	to determine the prevalence of bacteremia caused by bartonella henselae in domestic cats in the region of freiburg, germany, we investigated culture of blood from 100 cats from 89 different households over a 12-month period. b. henselae could be isolated from 13% (13 of 100) of these cats. in eight households with two cats each and in one household with three cats, b. henselae bacteremia was found either in all of the animals or in none of the animals. positive cultures were more likely to be fo ...	1997	9041393
the expanding spectrum of bartonella infections: ii. cat-scratch disease.	recent advancements and developments in molecular biotechnology have allowed more precise reclassification of many microorganisms. with the use of these new taxonomy tools, several organisms previously thought to belong to other genera have been recently described as bartonellae. of the 11 organisms now described as bartonella spp., only four have been shown to be pathogenic for humans. table 1 lists the four bartonella human pathogens along with the their known epidemiology and the scope and ra ...	1997	9041596
in vitro susceptibilities of bartonella henselae, b. quintana, b. elizabethae, rickettsia rickettsii, r. conorii, r. akari, and r. prowazekii to macrolide antibiotics as determined by immunofluorescent-antibody analysis of infected vero cell monolayers.	the in vitro susceptibilities of bartonella (rochalimaea) henselae, b. quintana, b. elizabethae, rickettsia akari, r. conorii, r. prowazekii, and r. rickettsii to different concentrations of azithromycin, clarithromycin, dirithromycin, erythromycin, and roxithromycin in vero cell cultures were evaluated. bartonella and rickettsia spp. were allowed to initiate infection of the antibiotic-free vero cell monolayers, which were maintained in 16-chamber microscope slides in the absence of antibiotics ...	1997	9055996
survey of veterinary professionals and other veterinary conference attendees for antibodies to bartonella henselae and b quintana.	to determine serologic and epidemiologic characteristics of an occupational group potentially at risk for bartonella sp infection.	1997	9057914
acute multifocal retinitis.	to describe the clinical presentation, ophthalmoscopic and fluorescein angiographic findings, and natural history of 14 eyes in nine otherwise healthy, young-to-middle-age adults with idiopathic, acute, multifocal retinitis.	1997	9063244
hepatosplenic cat-scratch disease and abdominal pain.	there have been several recent reports that cat-scratch disease (csd) causes a multiplicity of atypical clinical syndromes. we recently diagnosed hepatosplenic csd in a child who was seen with fever and abdominal pain. we report this case and 10 other patients with hepatosplenic csd and highlight the importance of abdominal pain in this clinical entity.	1997	9076813
[cat-scratch disease. a report of 4 cases and a review of the literature].	four cases of cat-scratch diseases are here reported and a review of the literature is made. the disease, apart from its typical presentation form as a usually self-limited regional lymph node enlargement, can occasionally spread and involve several organs systems. indirect immunofluorescence serological tests have been of help for its diagnosis and should be included among the diagnostic criteria for the disease. in particular cases, nuclear magnetic resonance can be useful to suggests the diag ...	1997	9102668
cat-scratch disease and related clinical syndromes.	bartonella (rochalimaea) henselae is a common cause of cat-scratch disease. this newly identified bacterium is also the cause of several other clinical syndromes, including bacillary angiomatosis, bacillary peliosis hepatitis and splenitis, and acute and relapsing bacteremia. a high percentage of young cats carry b. henselae. fortunately, serious complications of b. henselae infections are rare in immunocompetent patients. cat-scratch disease is usually a self-limited illness that does not neces ...	1997	9105205
bartonella spp. as emerging human pathogens.	members of the genus bartonella (formerly rochalimaea) were virtually unknown to modern-day clinicians and microbiologists until they were associated with opportunistic infections in aids patients about 6 years ago. since that time, bartonella species have been associated with cat scratch disease, bacillary angiomatosis, and a variety of other disease syndromes. clinical presentation of infection with bartonella ranges from a relatively mild lymphadenopathy with few other symptoms, seen in cat s ...	1997	9105751
pathogenetic role of phagocytic abnormalities in human virus immunodeficiency infection: possible therapeutical approaches. a review.	polymorphonuclear cells (pmn) and monocytes/macrophages (m/m) represent the first defence line against invading microorganisms. both phagocytic cell functions are precociously compromised in human immunodeficiency virus (hiv)-infected subjects, thus leading to infectious and neurological complications in the late stages of disease. among intracellular pathogens, emerging bacteria such as bartonella henselae and rhodococcus equi can cause peculiar clinical pictures, i.e. the bacillary parenchimal ...	1997	9130002
flea-borne rickettsioses: ecologic considerations.	ecologic and economic factors, as well as changes in human behavior, have resulted in the emergence of new and the reemergence of existing but forgotten infectious diseases during the past 20 years. flea-borne disease organisms (e.g., yersinia pestis, rickettsia typhi, r. felis, and bartonella henselae) are widely distributed throughout the world in endemic-disease foci, where components of the enzootic cycle are present. however, flea-borne diseases could reemerge in epidemic form because of ch ...	1997	9284376
bartonellosis in ecuador: serosurvey and current status of cutaneous verrucous disease.	human bartonellosis is a classically biphasic disease caused by infection with the alpha-2 proteobacteria bartonella bacilliformis, which is phylogenetically related to the etiologic agents of cat scratch disease, bacillary angiomatosis, and trench fever. in ecuador, typical bartonellosis has remained endemic for the past century in highland provinces near the peruvian border. during the past six years, public health officials have noted an increasing number of atypical cases in which monophasic ...	1997	9288812
epidemiologic evaluation of the risk factors associated with exposure and seroreactivity to bartonella vinsonii in dogs.	to determine seroprevalence to bartonella vinsonii subsp berkhoffii in a population of sick dogs from north carolina and virginia and to evaluate potential risk factors associated with increased likelihood of exposure to the organism.	1997	9140552
relapsing bacteremia after blood transmission of bartonella henselae to cats.	to determine persistence of bacteremia, pathogenicity, and immunoglobulin kinetics after blood transmission of bartonella henselae in cats.	1997	9140557
cat-scratch disease in a patient undergoing haemodialysis.		1997	9141021
a carboxy-terminal processing protease gene is located immediately upstream of the invasion-associated locus from bartonella bacilliformis.	a gene with homology to those encoding an unusual class of c-terminal processing proteases that flanks the invasion-associated locus ialab of bartonella bacilliformis has been identified. the 1302 bp gene, termed ctpa, is located immediately upstream of the iala gene and encodes a predicted nascent product of 434 amino acids, producing a mature protein of 411 amino acid residues. the bartonella ctpa appears to undergo autolysis in vitro, producing multiple products of 43-46 kda, and a second gro ...	1997	9141685
bacillary angiomatosis associated with myositis in a patient infected with human immunodeficiency virus.	a man with aids presented with a deep soft-tissue mass involving the right thigh. biopsy of a skin lesion on the back and culture of a specimen from this lesion showed bacillary angiomatosis due to bartonella (formerly rochalimaea) quintana. magnetic resonance imaging revealed a large heterogeneous mass involving the vastus medialis and intermedius muscles. therapy with erythromycin caused rapid resolution of both the cutaneous lesion and the muscle lesion. bartonella infection is proposed as an ...	1997	9145727
cat scratch disease in a child.	we report a case of a 9-year-old girl scratched on the right side of her neck by a kitten about one month prior to admission. she was well until three weeks later when she developed enlarged right neck masses, a pustula on the scratch site, right injected conjunctiva, headache, general malaise and fever, thus fulfilling the clinical criteria for csd. initially, she was treated by a practicing physician but the manifestations persisted for one week. after admission, leukocytosis and a mildly elev ...	1997	9151470
[2 patients with atypical manifestations of cat-scratch disease].	in 2 boys aged 8 years and 10 months, respectively, uncommon manifestations of cat scratch disease were seen. the first patient had acute encephalopathy: coma and generalized tonic-clinic convulsions. the second patient was presented with fever and peripheral lymphadenopathy in combination with hypodense lesions in the liver on ultrasound. diagnosis was established on the clinical picture and the positive results of serological testing of antibody titres for bartonella henselae. both patients re ...	1997	9157299
[visceral granulomas and pericardial effusion caused by a bartonella henselae infection].	a 57 year-old woman was seen after a three-week period of upper abdominal pain, nausea, fever, headache and exertional dyspnoea. laboratory examination showed an elevated esr and serum gamma-gt activity. the chest x-ray showed cardiomegaly resulting from a pericardial effusion as was demonstrated by echocardiography. an abdominal ct-scan disclosed multiple hypodense lesions in the liver and spleen and lymphadenopathy along the hepatoduodenal ligament. liver biopsy showed a necrotising granulomat ...	1997	9157300
cat scratch disease as a rare cause of obstructive jaundice: a case report.		1997	9157863
prevalence of bartonella henselae and bartonella clarridgeiae in stray cats.	the aim of the present work was to determine by blood culture the prevalence of blood infection with bartonella species in a well-defined, european, urban stray cat population. therefore, 94 stray cats were trapped from 10 cat colonies. blood samples of these cats were cultured on both blood agar and liquid medium in order to raise the likelihood of bacterial detection. fifty blood samples (53%) gave a positive culture result for bartonella species. isolate identification was performed by sequen ...	1997	9163438
seroprevalence of immunoglobulin g antibodies to bartonella henselae in cat owners.		1997	9177972
infective endocarditis due to unusual or fastidious microorganisms.	infective endocarditis due to fastidious microorganisms is commonly encountered in clinical practice. some organisms such as fungi account for up to 15% of cases of prosthetic valve infective endocarditis, whereas organisms of the hacek group (haemophilus parainfluenzae, h. aphrophilus, and h. paraphrophilus, actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens, and kingella kingae) cause 3% of community-acquired cases of infective endocarditis. special techniques a ...	1997	9179137
bartonella infections.		1997	9189670
[cat-scratch disease--an overlooked disease in denmark?].	only one patient with cat-scratch disease (csd) has been reported in denmark. a case and retrospective investigation among patients admitted to the ward is presented. over a period of 3.5 years, six patients were found to have suffered from csd. the yearly incidence was calculated to 2.6/100,000. the patients were tested for antibodies against bartonella (rochalimaea) henselae with a new test developed at the danish serum institute. only two of the patients with csd had titres of antibodies high ...	1997	9190717
bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease).	shortly after adopting a 6-week-old cat, a veterinarian was bitten on the left index finger. within 3 weeks, he developed headache, fever, and left axillary lymphadenopathy. initial blood cultures from the cat and veterinarian were sterile. repeat cultures from the cat grew bartonella-like organisms with lophotrichous flagella. sera from the veterinarian were not reactive against bartonella henselae, b. quintana, or b. elizabethae antigens but were seroreactive (reciprocal titer, 1,024) against ...	1997	9196200
culture-negative endocarditis: contribution of bartonella infections.	two cases of bartonella endocarditis are described: one in a 55 year old homeless alcoholic man, caused by bartonella quintana; the other in a 41 year old male with a history of exposure to cat fleas, caused by b henselae. serological testing and polymerase chain reaction of the excised valves were used to identify the organisms. false positive serology for chlamydia was detected in one case.	1997	9196420
detection of antibodies to bartonella henselae in clinically diagnosed cat scratch disease.	to determine the usefulness of an indirect immunoflourescence antibody test for antibodies to bartonella henselae in diagnosing cat scratch disease (csd).	1997	9196486
trench fever among homeless people in marseille, france: a seroprevalence survey.		1997	9196653
never discount an animal vector.		1997	9197061
[cat-scratch disease: historical, clinical, phylogenetic and taxonomic aspects].	the cat-scratch disease (csd) is known as a nosological entity since 1950. it was diagnosed by the clinical symptoms, epidemiologic data, and the intracutaneous test of hanger and rose. the aetiologic agent is bartonella (formerly rochalimaea) henselae occurring in thirty to fifty percent of healthy cats. the gramnegative alpha-2-proteobacteria cause the csd but also fever in healthy humans. patients suffering from aids show bacillary angiomatosis, bacillary peliosis hepatis, endocarditis, and s ...	1997	9198973
[cat scratch disease and associated infections].	cat scratch disease (csd) was first described in france by debré et al. in 1950, yet the causative bacterial agent of csd remained obscure until 1992, when bartonella (formerly rochalimaea) henselae was implicated in csd by serological and microbiologic studies. b. henselae had been linked initially to bacillary angiomatosis (ba), but also bacillary peliosis, relapsing bacteremia and endocarditis. cats are healthy carriers of b. henselae and b. clarridgeiae, and can be bacteremic for months to y ...	1997	9203735
molecular diagnosis of deep nodular bacillary angiomatosis and monitoring of therapeutic success.	a 51-year-old human immunodeficiency virus (hiv)-positive male patient (cdc stage 3c) had had a painful nodule on his external ankle joint for 10 months. a biopsy suggested bacillary angiomatosis, but kaposi's sarcoma could not be excluded. rods were detectable in lesional skin by a warthin-starry stain. a 298 base pair (bp) gene fragment specific for bartonella species was amplified from lesional skin and direct nucleotide sequence analysis of the amplification product clearly identified barton ...	1997	9205511
experimental infection of young specific pathogen-free cats with bartonella henselae.	eighteen 12-week-old specific pathogen-free cats, blood culture- and serum antibody-negative for bartonella henselae, were randomly allocated to groups and were intravenously inoculated with 10(10) (group 1), 10(8) (group 2), or 10(6) (group 3) b. henselae or with saline (group 4) or were not inoculated (group 5). cats were humanely killed at 2, 4, 8, 16, and 32 weeks after inoculation. all b. henselae-inoculated cats were bacteremic by 2 weeks after infection. bacteremia persisted until 32 week ...	1997	9207369
application of polymerase chain reaction assay in the diagnosis of orbital granuloma complicating atypical oculoglandular cat scratch disease.	parinaud oculoglandular syndrome is uncommon. most cases are caused by cat scratch disease (csd), recently discovered to be associated with the pathogen bartonella henselae. before isolation of the micro-organism, diagnosis relied on the presence of characteristic clinical features. however, atypical cases could cause diagnostic problems. with the development of an indirect fluorescent antibody test and polymerase chain reaction (pcr) assay, oculoglandular csd can be diagnosed readily.	1997	9224472
rapid polymerase chain reaction-based detection of the causative agent of cat scratch disease (bartonella henselae) in formalin-fixed, paraffin-embedded samples.	bartonella (formerly rochalimaea) henselae (bh) plays a central role in cat scratch disease. a polymerase chain reaction (pcr)-based assay that can detect bh dna in formalin-fixed, paraffin-embedded (ff-pe) samples would have utility in the evaluation of processed lymph nodes suggestive of this disorder. fresh or ff-pe cultures of bh and related species were analyzed. thirteen lymph nodes (12 ff-pe and one fresh cell suspension) with necrotizing suppurative granulomatous inflammation and seven f ...	1997	9224751
the 75-kilodalton antigen of bartonella bacilliformis is a structural homolog of the cell division protein ftsz.	a genomic library of bartonella bacilliformis was constructed and screened with human anti-bartonella serum from a patient with the chronic, verruga peruana phase of bartonellosis. an immunoreactive clone isolated from this library was found to code for a 591-amino-acid protein with a high degree of sequence similarity to the ftsz family of proteins. the degree of amino acid identity between the b. bacilliformis protein (ftsz[bb]) and the other ftsz proteins is especially pronounced over the n-t ...	1997	9226264
molecular diagnosis of cat scratch disease: a two-step approach.	amplification of bartonella henselae dna has been proposed as a diagnostic test for cat scratch disease (csd). the sensitivities of the following three pcr assays were compared. pcr/rrna with universal primers amplifies part of the 16s rrna gene, followed by hybridization with a specific b. henselae probe; pcr/cs and pcr/hsp amplify portions of the glta and the htra genes, respectively, each followed by restriction fragment length polymorphism analysis. the threshold of detection of b. henselae ...	1997	9230357
pitfalls and fallacies of cat scratch disease serology: evaluation of bartonella henselae-based indirect fluorescence assay and enzyme-linked immunoassay.	the diagnostic value of the detection of immunoglobulin g (igg) and igm by bartonella henselae-based indirect fluorescence assay (ifa) and enzyme-linked immunoassay (eia) for the diagnosis of cat scratch disease (csd) was evaluated. the ifa was performed either with b. henselae that was cocultivated for a few hours with vero cells or with noncocultivated b. henselae as the antigen. additionally, the performance of a bartonella pcr hybridization assay based on the 16s rrna gene was determined and ...	1997	9230358
pcr amplification and comparison of nucleotide sequences from the groesl heat shock operon of ehrlichia species.	degenerate pcr primers derived from conserved regions of the eubacterial groesl heat shock operon were used to amplify groesl sequences of ehrlichia equi, ehrlichia phagocytophila, the agent of human granulocytic ehrlichiosis (hge), ehrlichia canis, bartonella henselae, and rickettsia rickettsii. the groesl nucleotide sequences were less conserved than the previously determined 16s rrna gene sequences of these bacteria. a phylogenetic tree derived from deduced groel amino acid sequences was simi ...	1997	9230387
coinfection with bartonella clarridgeiae and bartonella henselae and with different bartonella henselae strains in domestic cats.	bartonella clarridgeiae and several strains of bartonella henselae, the agent of cat scratch disease, with variations in the 16s rrna gene have been found to infect the blood of cats. an epidemiologic study of bartonella infection in domestic french cats revealed that of 436 cats sampled, 5 cats (1.1%) were coinfected with b. henselae and b. clarridgeiae and 2 cats (0.5%) were coinfected with two strains of b. henselae with variations in the 16s rrna gene, b. henselae type i and type ii. in an i ...	1997	9230394
bartonellosis and human immunodeficiency disease (aids): l-forms as persisters, activating factors, and mechanism of disease.	bartonella, genus proteus, can cause immunodepressive disease. the organisms, in parasitized red blood cells, may invade the brain and every other system and space in the human body. bartonella henselae is proposed to have a role in the pathogenesis of acquired immunodeficiency syndrome (aids) encephalopathy. bartonella bacilliformis produces two known toxins that can induce spasm and angiomatosis, respectively, and manifest as diseases associated with symptomatic aids. the skin lesions of barto ...	1997	9247895
bacillary angiomatosis, cat-scratch disease, and bartonellosis: what's the connection?		1997	9248882
sternal abscess due to bartonella (rochalimaea) henselae in a renal transplant patient.	bartonella henselae, previously called rochalimaea henselae, is the causative agent of cat scratch disease (csd) in immunocompetent subjects and bacillary angiomatosis in immunocompromised ones. bone lesions are common in bacillary angiomatosis, but not in csd. we present the case of a patient with a renal transplant treated by immunosuppressive therapy who developed a sternal abscess with a histological pattern of csd. the ct pattern was that of a lytic bone lesion with adjacent fluid collectio ...	1997	9259103
immunologic response to bartonella henselae as determined by enzyme immunoassay and western blot analysis.	bartonella henselae is now regarded as the etiologic agent of cat-scratch disease and a cause of bacillary angiomatosis. we examined the human immune response to bartonella henselae infection using a newly developed enzyme immunoassay (eia) and a western blot procedure using outer-membrane proteins. the eia showed 98.6% and 91.4% agreement with an indirect fluorescence method (ifa) for detection of igm and igg antibodies, respectively. by using western blot analysis, reactivity to an 8-kd band s ...	1997	9260762
ease of isolation and semiquantitative culture of bartonella henselae from cats in melbourne.		1997	9271032
current knowledge of bartonella species.	bartonella species are now considered emerging pathogens. of the 11 currently recognized species, four have been implicated in human disease, although only two have been encountered in europe. bartonella quintana infections are now being diagnosed among the urban homeless and deprived, manifesting as trench fever, and bartonella henselae has been shown to be the causative agent of cat scratch disease. both species also cause a variety of hiv-associated infections, including bacillary anglomatosi ...	1997	9272384
heat shock response and groel sequence of bartonella henselae and bartonella quintana.	transmission of bartonella species from ectoparasites to the mammalian host involves adaptation to thermal and other forms of stress. in order to better understand this process, the heat shock response of bartonella henselae and bartonella quintana was studied. cellular proteins synthesized after shift to higher temperatures were intrinsically labelled with [25s]methionine and analysed by gel electrophoresis and fluorography. the apparent molecular masses of three of the major heat shock protein ...	1997	9274034
prevalence of bartonella species in domestic cats in the netherlands.	cats have been shown to provide the only known reservoir of bartonella henselae, the causative agent of cat scratch disease. to determine the prevalence of bartonella bacteremia and antibodies in dutch cats, blood samples from 113 cats from shelters (sheltered cats), 50 pet cats, and 25 specific-pathogen-free (spf) cats were analyzed. culture and subsequent pcr-restriction fragment length polymorphism (rflp) analysis of the 16s-23s rrna intergenic region and 16s rrna gene pcr-hybridization assay ...	1997	9276397
serological cross-reactions between bartonella and chlamydia species: implications for diagnosis.	diagnosis of chlamydia or bartonella infections continues to rely mainly on serology. however, serological cross-reactions between members of these genera have recently been described. sera from eight patients originally diagnosed as having chlamydia pneumoniae endocarditis reacted with both chlamydia sp. and bartonella quintana antigens (microimmunofluorescence technique). adsorption of sera with b. quintana or c. pneumoniae antigens removed anti-c. pneumoniae antibodies, whereas adsorption wit ...	1997	9276403
central nervous system infection associated with bartonella quintana: a report of two cases.		1997	9282717
detection of bartonella henselae and bartonella quintana by a simple and rapid procedure using broad-range pcr amplification and direct single-strand sequencing of part of the 16s rrna gene.	objective: to detect directly bartonella henselae and bartonella quintana using culture-independent, molecular techniques, and to evaluate a simple and rapid procedure that allows uncultivable bacteria to be detected in usually sterile clinical specimens in a diagnostic laboratory. methods: from four clinical specimens proven to contain b. henselae (n=3) or b. quintana (n=1) dna, part of the 16s rrna gene was amplified using the polymerase chain reaction (pcr) and broad-range bacterial primers f ...	1997	11864111
human infection with bartonella species.		1997	11864213
endocarditis in a dutch patient caused by bartonella quintana.		1997	11864215
paronychia caused by bartonella henselae.		1997	10213558
[bartonella infections].		1996	9636758
bartonella (rochalimaea) quintana endocarditis in an algerian farmer.		1996	11866779
bartonella (rochalimaea) henselae in southern africa--evidence for infections in domestic cats and implications for veterinarians.	substantial evidence has recently accumulated showing domestic cats to be the principal reservoirs of bartonella henselae, the aetiological agent of human diseases including cat-scratch disease, bacillary angiomatosis, bacillary peliosis and a febrile bacteraemia syndrome. to determine the prevalence of antibodies reactive with bartonella henselae in cats from southern africa, indirect fluorescent antibody assays were carried out on feline sera from south africa and zimbabwe. overall, 23% (39/17 ...	1996	9284029
cat-scratch disease diagnosed serologically using an enzyme immunoassay in a patient with neuroretinitis.		1996	8602794
seroprevalence to bartonella quintana among patients at a community clinic in downtown seattle.	in 1993, an outbreak of 10 cases of bartonella quintana bacteremia occurred among homeless, alcoholic, human immunodeficiency virus (hiv)-negative persons in seattle. to estimate the prevalence of past exposure b. quintana among this population, a serosurvey was conducted in 1994 among patients at a downtown seattle clinic. microimmunofluorescent titers to b. quintana in 192 clinic patients were compared with titers in 199 age- and sex-matched seattle volunteer blood donors. titers > or = 64 wer ...	1996	8603944
mr imaging of the knee: findings in cat-scratch disease.		1996	8615286
carboxyl-terminal processing protease for the d1 precursor protein: cloning and sequencing of the spinach cdna.	a previous study has demonstrated that the carboxyl-terminal (c-terminal) processing protease in spinach for the d1 precursor protein (pdl) of the photosystem ii reaction center is a monomeric protein of about 45 kda. based on the amino acid sequence data of the purified protease, a cdna clone encoding the enzyme has been identified and sequenced, from a spinach green leaf cdna library. in order to determine the 5' end of the transcript, the rapid amplification of cdna end (5'-race) technique wa ...	1996	8616242
new serotype of bartonella henselae in endocarditis and cat-scratch disease.	the fastidious nature of bartonella henselae is such that demonstration of clinical infection relies mainly on serological or molecular biological methods. only five isolates have been obtained from patients with cat-scratch disease (csd) and none from endocarditis.	1996	8618486
[cat-scratch disease and other infections caused by bartonella species].	bartonella henselae, the causative agent of cat-scratch disease, was identified recently by dna amplification techniques. several other bartonellae (most of which were called rochalimaea before) cause disease in humans: b. bacilliformis (carrion's disease), b. elizabethae (endocarditis) and b. quintana (bacillary angiomatosis and peliosis, chronic bacteraemia and endocarditis, trench fever). b. henselae is transmitted to humans by scratch or bite of a bacteraemic, but asymptomatic, cat, which ev ...	1996	8618634
etiology of cat-scratch disease.		1996	8623713
emerging bacterial zoonotic and vector-borne diseases. ecological and epidemiological factors.	among the etiologic agents of emerging infectious diseases are several bacterial organisms that naturally reside in animal and arthropod hosts. the most compelling emerging bacterial zoonotic and vector-borne diseases in the united states are lyme disease; a southern erythema migrans-like illness; human monocytic ehrlichiosis; human granulocytic ehrlichiosis; a novel cat flea-associated typhus group rickettsiosis; bartonelloses of immunocompetent and immunocompromised persons, particularly with ...	1996	8627968
[cat scratch disease. bartonella henselae antibodies and dna detection in regional lymphadenopathy].	history and clinical findings: two hard, pressure-sensitive nodules developed in the lower jaw of a 22-year-old woman. after a dental cause had been excluded, she was treated for suspected tonsillitis with ceftibuten. erythrocyte sedimentation rate was increased to 18 mm in the first hour. there were no other significant biochemical findings and fine-needle biopsy of one of the nodules showed nonspecific inflammatory reaction. investigations: sonography revealed two lymph nodes, 7 and 22 mm in d ...	1996	8631227
isolation of bartonella henselae from domestic cats in japan.	during the period from january to march 1995, the authors first isolated bartonella henselae from the blood of three (9.1%) of 33 domestic cats in japan. the three cats were a 1.5-year male pet cat-old with urinary retention, and 6-year-old female pound and age-unknown female pet cats with no abnormalities. the blood was taken in a lysis-centrifugation tube (wampole isolator tube) and cultured on 5% rabbit-blood heart infusion agar plates at 35 degrees c in the 5% co2 atmosphere. visible tiny ro ...	1996	8645765
bartonella (rochalimaea) infections: beyond cat scratch.	five species of bartonella have been found to infect humans, henselae, quintana, elizabethae, bacilliformis, and vinsonii. the most common of these in north america are bartonella quintana and bartonella henselae, the agents of trench fever, bacillary angiomatosis, and parenchymal peliosis, and in the case of b. henselae cat-scratch disease. b. bacilliformis is endemic in peru and ecuador, where it causes oroya fever or carrion's disease. new methods of diagnosing bartonella infections have resu ...	1996	8712787
bartonella (rochalimaea) quintana causing fever and bacteremia in an immunocompromised patient with non-hodgkin's lymphoma.	a 48-yr-old man with stage iv non-hodgkin's lymphoma, became neutropenic following chemotherapy and developed a fever. his blood cultures were processed to enhance the yield of fastidious bacteria. a slow-growing, capnophilic gram-negative rod was isolated. the febrile episode was treated with cefotaxime, imipenem and vancomycin and resolved. the bacterial isolate was identified as bartonella (rochalimaea) quintana by 16s-rdna gene sequencing. the isolate showed 99.8% sequence homology with the ...	1996	8714279
bartonella infections.		1996	8718458
[detection of bartonella (rochalimaea) henselae/b. quintana by polymerase chain reaction (pcr)].	bartonella (rochalimaea) henselae and/or b. quintana are the causative agents of a variety of infections such as trench fever, bacillary angiomatosis, septicemia, peliosis hepatis and endocarditis. recently, b. henselae has been identified as a major cause of cat scratch disease. diagnosis of such infections is based on clinical information, histopathology, culture and serology. however, none of these methods alone is sufficiently sensitive or specific. we have used the pcr to search for dna spe ...	1996	8720724
q fever and trench fever.		1996	8727131
bacillary angiomatosis.		1996	8727133
bartonella (rochalimaea) quintana infection in a seronegative hemodialyzed patient.	bartonella quintana is a reemerging pathogen responsible for trench fever, endocarditis, bacteremia, and bacillary angiomatosis. we previously reported the first case of a patient with b. quintana-induced chronic adenomegaly, and here we present a report on a second patient. a hemodialyzed patient with sjögren's syndrome presented with mediastinal adenomegalies and secondary pancytopenia. all diagnostic investigations remained negative, except that a bartonella-like microorganism was isolated fr ...	1996	8727894
bartonella (rochalimaea) henselae hepatosplenic infection occurring simultaneously in two siblings.		1996	8729220
[visceral localizations of cat-scratch disease in an immunocompetent patient].	locoregional expression of cat scratch disease is well known, but despite advances in microbiology over the last 10 years leading to the description of two new bacteria (afipia felis, bartonella henselae) the infective agent responsible for cat scratch syndrome remains unknown. until the 80s, only one systemic disease was attributed to infection with a germ in the bartonella genus: trench fever. with the onset of the aids epidemic, new clinical syndromes caused by bartonella bacteria have been d ...	1996	8729380
emergence of bartonella quintana infection among homeless persons.		1996	8903217