Publications

[bacterial colonization and home mechanical ventilation: prevalence and risk factors].	to investigate the prevalence of bacterial contamination of ventilators and colonization of patients, the bacteria implicated, and predisposing factors in noninvasive home ventilation.	2004	15458614
beta-lactam susceptibilities and prevalence of esbl-producing isolates among more than 5000 european enterobacteriaceae isolates.	in vitro susceptibility to 15 beta-lactam antibiotics was evaluated using enterobacteriaceae isolated during the sentry antimicrobial surveillance program. piperacillin/tazobactam was the most active penicillin against escherichia coli, proteus mirabilis, klebsiella oxytoca and klebsiella pneumoniae (94.9%, 98.3%, 87.4% and 82.9% of isolates susceptible). of the cephalosporins, cefepime was most effective against escherichia coli, proteus mirabilis and enterobacter cloacae (99.2%, 96.3% and 95.2 ...	2004	15555882
use of translational fusion of the mrph fimbrial adhesin-binding domain with the cholera toxin a2 domain, coexpressed with the cholera toxin b subunit, as an intranasal vaccine to prevent experimental urinary tract infection by proteus mirabilis.	this is a follow-up to our previous study using an intranasal vaccine composed of mrph, the tip adhesin of the mr/p fimbria, and cholera toxin to prevent urinary tract infection by proteus mirabilis (x. li, c. v. lockatell, d. e. johnson, m. c. lane, j. w. warren, and h. l. mobley, infect. immun. 72:66-75, 2004). here, we have expressed a cholera toxin-like chimera in which the mrph adhesin-binding domain (residues 23 to 157) replaces the cholera toxin a1 adp-ribosyltransferase domain. this chim ...	2004	15557656
s-adenosylmethionine and pneumocystis.	pneumocystis is a parasitic fungus causing pneumonia in immunosuppressed mammals and s-adenosylmethionine a key intermediary metabolite for all cells. other than a species of rickettsia bacteria and an aberrant strain of the protozoan amoeba proteus, pneumocystis is the only cell known unable to synthesize adomet; it must extract this key compound from its host. this was discovered using a culture system and confirmed by observing depletion of adomet in the plasma of infected animals. depletion ...	2004	15321660
phylogenetic characterization of legionella-like endosymbiotic x-bacteria in amoeba proteus: a proposal for 'candidatus legionella jeonii' sp. nov.	the x-bacteria which initiated organismic association with the d strain of amoeba proteus in 1966 as parasites have changed to obligate endosymbionts on which the host depends for survival. owing to the difficulty in cultivating the bacteria in vitro, the identity of x-bacteria has not been determined. as the life cycle of x-bacteria is similar to that of legionella spp. in soil amoebae, we applied the polymerase chain reaction method with specific primers aimed at legionella spp. for the detect ...	2004	15560823
cockroaches as potential vectors of nosocomial infections.	to determine the possible role of cockroaches in the epidemiology of nosocomial infections.	2004	15566034
species-dependent premature degradation of absorbable suture materials caused by infection--impact on the choice of thread in vascular surgery.	in case of infection after vascular reconstruction, preference is often given to absorbable suture material with the aim of preventing persistence of infection. we have investigated the functional deficit of absorbable sutures on incubation with various different bacteria.	2004	15461069
[antimicrobial activity of new original 2-aryliden-6-furfuryliden cyclohexanones and hexahydroindazoles on their basis].	antimicrobial activity of 25 new original 2-aryliden-6-furfuryliden cyclohexanones and hexahydroindazoles based on them was studied. the majority of the compounds had low or moderate activity against the test cultures of staphylococcus spp., pseudomonas aeruginosa, proteus spp. and escherichia coil. compound xix (2,3-diphenyl-7-(5-nitrofurfuryliden)-3,3a,4,5,6,7-hexahydroindazole) with high antistaphylococcal activity was selected among several 2-aryliden-6-furfuryliden cyclohexanones and hexahy ...	2004	15460019
[microbiocenosis of the bowels in patients with gastroduodenal ulcers].	gastroduodenal ulcer is accompanied by the bowels dysbacteriosis irrespective of the helicobacter pylori infection. any variant of ulcer treatment aggravates the bowels dysbacteriosis intensity. eradication therapy destroys bifidobacteria mostly.	2004	15462314
klippel-trénaunay syndrome: the importance of "geographic stains" in identifying lymphatic disease and risk of complications.	klippel-trénaunay syndrome (kts) is a rare congenital anomaly classically defined as the triad of vascular stain, soft tissue and/or bony hypertrophy, and venous varicosities.	2004	15337982
correlation of extended spectrum beta lactamases production with cephalosporin resistance in gram negative bacilli.	beta lactamase production is an important mechanism of developing resistance to beta lactam group of antibiotics. cephlosporins with extended spectrum of activity and stability were introduced to overcome this resistance, but soon production of extended spectrum beta lactamases (esbls), which are inducible in nature was reported. in this study klebsiella aerogenes--166, escherichia coli--120, citrobacter spps--116, pseudomonas spps--50, proteus spps--32 and s. typhi--16, strains were subjected t ...	2004	15471144
digestion of cellulose and xylan by symbiotic bacteria in the intestine of the indian flying fox (pteropus giganteus).	bats (order chiroptera) are a widely distributed group of mammals. pteropus giganteus belongs to the suborder megachiroptera. this bat consumes fruits and leaves as their major food. cellulose and xylan are the major composition of leaves. as they consume leaves in their diet, their digestive tract must contain cellulolytic and xylanolytic bacteria which help in the digestion of cellulose and xylan. the cellulolytic and xylanolytic bacteria were isolated and screened on berg's agar containing ce ...	2004	15471682
[effect of delay of blood cultures on positive detection by automated blood culture system].	the effect of entry delayed blood culture bottles until the start of incubation for mechanical detection of organism were compared using 2 major blood culture systems; bactec 9240 system and bact/alert 3d system. total of 13 bacterial strains; 5 gram-positive cocci, 7 gram-negative bacilli and candida parapsilosis which were isolated mainly from blood cultures were used as the test strains. bactec 92f, 93f and bact/alert fa, fn bottles were used as the blood culture bottles. all the bottles inoc ...	2004	15628528
a novel glutamate-dependent acid resistance among strains belonging to the proteeae tribe of enterobacteriaceae.	morganella, providencia and proteus strains were capable of surviving ph 2.0 for 1 h if glutamate was present. these strains did not have glutamic acid decarboxylase activity and the gadab genes were not detected in any of these bacteria. when exposed to ph 2.0 acid shocks, the survival rate of these bacteria was significantly increased with glutamate concentrations as low as 0.3 mm in the acid media. escherichia coli cells incubated at ph 3.4 consumed four times more glutamate and produced at l ...	2004	15321677
defense function of pigment granules in the ciliate blepharisma japonicum against two predatory protists, amoeba proteus (rhizopodea) and climacostomum virens (ciliata).	the defense function of pigment granules in the red ciliate blepharisma japonicum against two predatory protists, amoeba proteus and climacostomum virens, was investigated by (1) comparing normally-pigmented and albino mutant cells of b. japonicum as the prey of these predators and (2) comparing resistance of the predators to blepharismin, the toxic pigment contained in the pigment granules of b. japonicum. normally pigmented cells which contained more blepharismin than albino cells were less vu ...	2004	15333994
effects of trifluoromethyl ketones on the motility of proteus vulgaris.	in the present study, we showed the inhibition of motility by trifluoromethyl ketone (tf) derivatives (1-8) in proteus vulgaris (p. vulgaris) cultures. among them, 1-(2-benzoxazoyl)-3,3,3-trifluoro-2-propanone (1) showed a much stronger inhibitory effect on the motility of p. vulgaris than other tf compounds at 10% mic. our results suggest the possibility of an inhibitory action of tf compounds on the proton motive forces by affecting the action of biological motor and proton efflux in the membr ...	2004	15340240
epidermal nevus syndromes: clinical findings in 35 patients.	of the patients with epidermal nevi, 10-18% may have disorders of the eye, nervous, and musculoskeletal systems. a predisposition to malignant neoplasms in ectodermal and mesodermal structures may also be found. there are six different epidermal nevus syndromes described so far: proteus, congenital hemidysplasia with ichthyosiform nevus and limb defect syndrome, phakomatosis pigmentokeratotica, sebaceous nevus, becker nevus, and nevus comedonicus. thirty-five patients with epidermal nevus syndro ...	2004	15283784
otitis externa infection in jordan. clinical and microbiological features.	aims of this study were to investigate the clinical findings and to identify causative microorganisms and their susceptibility to antibiotics in otitis externa infection.	2004	15448765
cutaneous manifestations of proteus syndrome: correlations with general clinical severity.	proteus syndrome is a rare congenital disorder with progressive asymetric overgrowth of multiple tissues.	2004	15313810
proteus mirabilis zapa metalloprotease degrades a broad spectrum of substrates, including antimicrobial peptides.	the 54-kda extracellular metalloprotease zapa is an important virulence factor of uropathogenic proteus mirabilis. while zapa has the ability to degrade host immunoglobulins (igs), the dramatic attenuation of virulence in zapa mutants suggests that this enzyme may have a broader spectrum of activity. this hypothesis was tested by in vitro assays with purified zapa and an array of purified protein or peptide substrates. the data reveal that many proteins found in the urinary tract are substrates ...	2004	15322010
pcr method based on the ogdh gene for the detection of salmonella spp. from chicken meat samples.	in a previous paper, the ogdh gene that encodes 2-oxoglutarate dehydrogenase was isolated from salmonella typhimurium. the catalytic n-terminal region in the enzyme was found to be very specific for the salmonella species. therefore, the aim of the present study was to detect s. typhimurium in food sources using primers designed for ogdh-1 and ogdh-2 which were based on the salmonella-specific region of the ogdh gene. a simple polymerase chain reaction (pcr) detection method was developed to det ...	2004	15459651
[causes of urinary tract infection in pregnant women].	data of etiology characteristics of uroinfections with pregnant women are presented treated at university hospital of obstetrics and gynecology "maichin dom" in three periods. gram negative species of microorganisms (e. coli, proteus, klebsiella) are the agens of uroinfections in 95.4% of cases in the period 1988/89. after 10-year period gram (-) are the uroinfection in 66.1% of the cases. the growing etiologycal importance of gram positive species of microorganisms (s. aureus, enterococcus, gbs ...	2004	15341251
poly(vinyl chloride)-coated sol-gels for studying the effects of nitric oxide release on bacterial adhesion.	nitric oxide (no) releasing sol-gel materials coated with poly(vinyl chloride) (pvc) films exhibit increased stability at ambient and physiological temperatures. the polymer overcoat, however, reduces the no fluxes by 5-35% over the initial week of release. the variation in no fluxes between unmodified and pvc-coated sol-gels is negligible after 7 days. the pvc polymeric layer provides controlled surface chemistry for systematic studies of the effects of no release on bacterial adhesion. as an e ...	2004	15360321
nosocomial transmission of ctx-m-2 beta-lactamase-producing acinetobacter baumannii in a neurosurgery ward.	three strains of cefotaxime (ctx)-resistant acinetobacter baumannii, fm0209680, fm0300106, and fm0301433, were isolated from transtracheal aspirate cultures of three patients with probable nosocomial infections in a neurosurgery ward in japan. the ctx mics for these isolates were greater than 128 microg/ml but were drastically reduced in the presence of 4 microg of clavulanic acid per ml. these strains were also resistant to ceftriaxone, cefpodoxime, and aztreonam but were susceptible to ceftazi ...	2004	15364979
microbiological quality of fermented cassava flour 'kpor umilin'.	a study was conducted on the microbiological quality of traditionally fermented cassava flour 'kpor umilin' and a laboratory modification of the method developed with a view to upgrading the traditional process. microbial analysis of samples from both processing methods was evaluated using standard microbiological methods. the bacterial count in the traditionally processed flours ranged from 2.7 x 10(3) to 1.2 x 10(7) cfu/g, while the modified sample had a count of 3.5 x 10(2) cfu/g. the predomi ...	2004	15369985
evaluation of the microscan esbl plus confirmation panel for detection of extended-spectrum beta-lactamases in clinical isolates of oxyimino-cephalosporin-resistant gram-negative bacteria.	we aimed to assess the performance of the microscan esbl plus confirmation panel using a series of 87 oxyimino-cephalosporin-resistant gram-negative bacilli of various species.	2004	15471997
diagnosis of proteus syndrome was correct.		2004	15372511
detection of staphylococcus aureus enterotoxin a and b genes with pcr-eia and a hand-held electrochemical sensor.	two electrochemical assays for detecting staphylococcus aureus enterotoxin a and b genes were developed. the assays are based on pcr amplification with biotinylated primers, hybridization to a fluorescein-labeled probe, and detection with horseradish peroxidase-conjugated anti-fluorescein antibody using a hand-held electrochemical detector. the limit of detection (lod) for both assays was approximately 16 copies of the sea and seb genes. the assays were evaluated in blinded studies, each with 81 ...	2004	15488376
micredox--development of a ferricyanide-mediated rapid biochemical oxygen demand method using an immobilised proteus vulgaris biocomponent.	biochemical oxygen demand (bod) is an international regulatory environmental index for monitoring organic pollutants in wastewater and the current legislated standard test for bod monitoring requires 5 days to complete (bod5 test). we are developing a rapid microbial technique, micredox, for measuring bod by eliminating oxygen and, instead, quantifying an equivalent biochemical co-substrate demand, the co-substrate being a redox mediator. elevated concentrations of proteus vulgaris, either as fr ...	2004	15494235
incidence of enteric bacteria and staphylococcus aureus in day care centers in akwa ibom state, nigeria.	the incidence of enteric bacteria and staphylococcus aureus in four day care centers in akwa ibom state was studied using culture techniques. the percentage frequencies of the isolates from 124 samples were staphylococcus aureus (33.9), escherichia coli (19.0), klebsiella sp (14.4), citrobacter sp (12.5) and proteus mirabilis (7.4). the sources of contamination were floors, chairs, skin, bed linen, door handles, fans, children's tables, walls, windows, ceiling, headmistress's table and chairs, d ...	2004	15272770
mutation analysis of the tumor suppressor pten and the glypican 3 (gpc3) gene in patients diagnosed with proteus syndrome.	proteus syndrome is a complex hamartomatous disorder characterized by asymmetrical gigantism, epidermal nevi, vascular malformations, hamartomas, lipomas, and hyperostosis. since the syndrome was first described, many hypotheses have been proposed to explain its occurrence. the most plausible is happle's somatic mosaic hypothesis, but no somatic mutations in candidate genes have been reported to be clearly involved in proteus syndrome. however, germ-line pten mutations have been reported in pati ...	2004	15372512
reassessment of the proteus syndrome literature: application of diagnostic criteria to published cases.	the medical care of patients affected by rare disorders depends heavily on experiences garnered from prior cases, including those patients evaluated by the treating physician and those published in the medical literature. the utility of published cases is wholly dependent upon accurate diagnosis of those patients. in our experience, the rate of misdiagnosis in proteus syndrome (ps) is high. diagnostic criteria have been published, but these criteria have not been applied consistently and were pu ...	2004	15372514
traditional medicine in sakarya province (turkey) and antimicrobial activities of selected species.	traditional medicine in north-west of turkey (sakarya province) were studied during a 2 months field study by interviewing local informants from several villages. plant species used to treat infections were tested for antimicrobial activity. information was collected for 46 plant species from 30 families and for 5 animal species. twenty four of the plant species were cultivated. most used families were asteraceae, cucurbitaceae, lamiaceae and rosaceae and the most used plants were artemisia absi ...	2004	15507351
prulifloxacin.	prulifloxacin, the prodrug of ulifloxacin, is a broad-spectrum oral fluoroquinolone antibacterial agent. after absorption, prulifloxacin is metabolised by esterases to ulifloxacin. the drug has a long elimination half-life, allowing once-daily administration. ulifloxacin is generally more active in vitro than other fluoroquinolones against a variety of clinical isolates of gram-negative bacteria, including community and nosocomial isolates of escherichia coli, klebsiella spp., proteus, providenc ...	2004	15456336
detection of ticarcillin-clavulonic acid susceptibility with microdilution method in citrobacter, hafnia, proteus and some gram negative bacteria.	the broth dilution method has been regarded as a good alternative test for detection of susceptibilities to antimicrobial agents. in this study, the antimicrobial activity of ticarcillin-clavulonic acid (tim) was investigated by the minimal inhibitory concentration (mic) method on strains of aeromonas, citrobacter, hafnia, morganella, proteus, pseudomonas and gram negative bacteria isolated from raw milk. the isolate collection included 91 gram negative strains. fifty-one (56.04%) isolates were ...	2004	15508433
rapidly rising prevalence of nosocomial multidrug-resistant, gram-negative bacilli: a 9-year surveillance study.	to examine and quantify the temporal trends of nosocomial multidrug-resistant, gram-negative bacilli.	2004	15518026
[urinary stones in tunisian infants, based on a series of 64 cases].	to define the epidemiological and clinical characteristics of urinary stones in infants, to study the role of stone chemical analysis in the aetiological assessment of urinary stones and to define the various treatment modalities adapted to this age-group.	2004	15373180
mucosal vaccination of mice with recombinant proteus mirabilis structural fimbrial proteins.	proteus mirabilis, a common cause of urinary tract infection (uti), expresses several types of fimbria including mannose-resistant/proteus-like fimbriae (mrp), uroepithelial cell adhesin (uca), renamed non-agglutinating fimbriae (naf) by some authors, and p. mirabilis fimbriae (pmf), which are potentially involved in adhesion to the uroepithelium. in this study, we immunised different groups of mice with recombinant structural subunits of these fimbriae (mrpa, ucaa and pmfa) using two mucosal ro ...	2004	15374007
[xanthogranulomatous pyelonephritis: clinical, radiological and pathologic characteristics].	xanthogranulomatous pyelonephritis is an atypical chronic infection which simulates a malignant renal neoplasia, definitive diagnosis of which is obtained by pathologic study after surgical removal. in this paper we analyze our experience and compare it to that reported on the literature.	2004	15382434
antimicrobial effect of water extract of sumac (rhus coriaria l.) on the growth of some food borne bacteria including pathogens.	the antimicrobial effect of water extracts of sumac (rhus coriaria l.) at concentrations of 0.1%, 0.5%, 1.0%, 2.5% and 5.0% (w/v), non-neutralized and after neutralization to ph 7.2+/-0.1, was studied on the growth of 12 bacterial strains (six gram positive strains and six gram negative strains), mostly food borne including pathogens. it was found to be effective against all the test organisms with gram positive strains being more sensitive than gram negative strains. significant differences (p< ...	2004	15527919
intestinal microflora in 45 crows in ueno zoo and the in vitro susceptibilities of 29 escherichia coli isolates to 14 antimicrobial agents.	microorganisms from 45 jungle crows (corvus macrorhynchos) captured from july to december 2002 at ueno zoo, tokyo were identified as escherichia coli, proteus mirabilis, klebsiella pneumoniae, klebsiella oxytoca, enterobacter aerogenes, enterobacter cloacae, enterobacter agglomerans, pseudomonas maltophila, staphylococcus spp., micrococcus spp., and streptococcus spp. e. coli showed the highest rate of isolation (21.6%). in an in vitro susceptibility test for 29 isolates of e. coli to 14 antimic ...	2004	15528866
effect of ceftazidime, amikacin and ciprofloxacin on biofilm formation by some enterobacterial clinical isolates.	the effect of sub-minimal inhibitory concentrations of antimicrobial agents on the biofilm formationto polystyrene by escherichia coli, proteus vulgaris, providencia stuartii, and morganella morganii was investigated by examining eight clinical strains. all the isolates tested were efficient biofilm-forming strains in the microtiter plate assay, with crystal violet staining (od595 nm) ranging from 0.13 +/- 0.01 for p. stuartii er21870 to 1.23 +/- 0.02 for p. vulgaris er50120. the biofilm formati ...	2004	15528892
in vitro antimicrobial properties of aqueous garlic extract against multidrug-resistant bacteria and candida species from nigeria.	the antimicrobial effects of aqueous garlic extract (age) against 133 multidrug-resistant gram-positive and gram-negative bacterial isolates, including staphylococcus aureus, staphylococcus epidermidis, streptococcus pneumoniae, streptococcus pyogenes, haemophilus influenzae, salmonella typhi, pseudomonas aeruginosa, escherichia coli, shigella spp., and proteus spp., and against 10 candida spp. were studied. antibacterial activity of age by well-diffusion and macrobroth dilution method was chara ...	2004	15383227
genetic and physiological interactions in the amoeba-bacteria symbiosis.	amoebae of the xd strain of amoeba proteus that arose from the d strain by spontaneous infection of legionella-like x-bacteria are now dependent on their symbionts for survival. each xd amoeba contains about 42,000 symbionts within symbiosomes, and established xd amoebae die if their symbionts are removed. thus, harmful infective bacteria changed into necessary cell components. as a result of harboring x-bacteria. xd amoebae exhibit various physiological and genetic characteristics that are diff ...	2004	15537083
the susceptibility of certain bacterial strains to imidazotriazine derivatives.	the synthesized imidazo[2,1-c]triazines were tested for their antimicrobial activity. microbiological screening tests conducted in relation to 54 strains of gram-positive and 52 strains of gram-negative bacteria, 6 strains of yeast-like fungi and 3 strains of moulds showed significant activity of compound 19 against 52 gram-negative bacterial strains. this compound was active against 16 strains of escherichia coli, 12 strains of pseudomonas, 10 strains of proteus spp., 8 strains of klebsiella pn ...	2004	16146057
oropharyngeal flora changes in patients with head and neck malignancy post radiotherapy.	radiotherapy has been recognized as a valuable modality of treatment in the management of head and neck cancers. it can have a direct bactericidal effect on the normal flora of the oropharynx. the objective of this study is to determine the changes in the oropharyngeal flora after external beam radiation. this prospective non randomized control study was performed to aid in identification of organisms involved in sepsis, as well as aid in choosing appropriate antibiotics for surgical procedures ...	2004	15889559
childhood urinary tract infection: a clinical analysis of 597 cases.	objectives of study: to gain new insights into the epidemiology, genitourinary (gu) tract anomalies, etiologies, susceptibility of urinary pathogens to antibiotics in children with urinary tract infection (uti) during the past decade in taiwan.	2004	15868848
urinary tract infection in children: incidence of vesicoureteral reflux, imaging studies, and antimicrobial resistance among e. coli.		2004	15868844
synthesis, spectra and biomimetic properties of copper(ii)-copper(ii) and copper(ii)-zinc(ii) binuclear complexes with cun5 chromophores.	x-band electron spin resonance (esr) and uv-vis spectra of a homobinuclear [(bipy)2cu-e-im-cu(bipy)2](bf4)3 and a heterobinuclear [(bipy)2cu-e-im-zn(bipy)2](bf4)3 complexes, e-im=2-ethylimidazolate ion have been described as possible models for superoxide dismutase (sod). magnetic moment and esr spectral measurements of the homobinuclear complex have shown an antiferromagnetic exchange interaction. from ph-dependent esr and uv-vis spectral measurements studies, these complexes have been found to ...	2004	16043054
recurrent urinary tract infections--uropathogen incidence and drug sensitivity.	the aim of the study was the retrospective analysis of the results of the drug sensitivity studies of bacterial species cultured from 681 urinary specimens collected from 79 children (12 boys and 67 girls) aged 0-18 years with recurrent urinary tract infection in a period from 1997 to 2001. factors predisposing to recurrent urinary tract infections and the incidences of particular uropathogens were also analyzed. escherichia coli (57.3%), proteus spp. (15.6%) and pseudomonas aeruginosa (9.1%) we ...	2004	16146092
bacteriology of diabetic foot lesions.	clinical grading and bacteriological study of 107 patients with diabetic foot lesions revealed polymicrobial aetiology in 69 (64.4%) and single aetiology in 21 (19.6%). among 107 patients 62 had ulcer. of these 31 had mixed aerobes. twenty six patients with cellulitis and 12 with gangrene had more than 5 types of aerobes and anaerobes such as e. coli, klebsiella spp., pseudomonas spp., proteus spp., enterobactor spp., enterococci spp., clostridium perfringens, bacteroides spp., prevotella spp. a ...	2004	17642727
bacteriological quality of some pharmaceutical products marketed by drug vendors in uyo, nigeria.	bacteriological quality of some pharmaceutical products purchased from open markets, buses and drug stores in uyo metropolis was studied in order to determine the level of contamination of the drugs. the drug samples examined were tetracycline capsules, paracetamol tablets, ampicillin capsules, chloroquine tablets, chloroquine syrup, chloroquine injections, flagyl tablets and chloramphenicol tablets. the bacterial count ranged from 2.3x10(4) cfu/g to 4.4x10(4) cfu/g for the 16 samples of ampicil ...	2004	17298130
evaluation of the antimicrobial activity of the acetone extract of the lichen ramalina farinacea and its (+)-usnic acid, norstictic acid, and protocetraric acid constituents.	the acetone extract of the lichen ramalina farinacea and its (+)-usnic acid constituent showed antimicrobial activity against bacillus subtilis, listeria monocytogenes, proteus vulgaris, staphylococcus aureus, streptococcus faecalis, yersinia enterocolitica, candida albicans, and candida glabrata. norstictic acid was active against aeromonas hydrophila as well as the above microorganisms except yersinia enterocolitica. protocetraric acid showed activity only against the tested yeasts candida alb ...	2004	18998406
depression - the proteus of medicine.	depression is discussed as a disease of antiquity with suitable contemporary references also. the prevalence of this disorder, which at a given time constitutes 121 millions world-wide is mentioned. among the types of depression, comorbid depression forms an important one. classical depression forms the visible part of the depression iceberg while somatic and other life contextual situation forms the submerged part. somatic manifestations per se do not carry diagnostic weightage unless the core ...	2004	21408045
a rapid method for determining mycobacterium tuberculosis based on a bulk acoustic wave impedance biosensor.	the bulk acoustic wave impedance biosensor was set up and used to monitor the growth of mycobacterium tuberculosis (m.tb). this sensor is rapid, simple, sensitive (lower limit is 2 x 10(3) cells ml(-1)) and cheap (easy to generalize). the typical response curve was different from other bacteria's, such as escherichia coli, staphylococcus aureus, proteus mirabilis. the frequency detection time was used to quantitatively determine m.tb. it was proportional to logarithm of the initial concentration ...	2003	18968982
polymicrobial osteomyelitis of the odontoid process with epidural abscess: case report and review of literature.	osteomyelitis of the odontoid process is a rare disease and staphylococcus aureus is the usual causative organism. we present a case caused by a synergistic infection with staphylococcus aureus and proteus mirabilis, which has not been reported previously. a high index of suspicion is required for diagnosis, and early institution of broad antimicrobial therapy, including agents active against gram-negative organisms, is mandatory.	2003	15912167
temporary catheter infections in hemodialysis patients: results from a single center in turkey.	in this study, we aimed to determine the frequencies of catheter exit-site infection (cesi), catheter-related bloodstream infection (cr-bsi) and catheter colonization (cc); causative microorganisms; and resistance patterns in patients with temporary hemodialysis catheters. from march 1999 to march 2000, 67 hemodialysis patients (38 males, 29 females; median age: 52, range: 17-84) were evaluated. the cdc criteria were used to diagnose cesi, cr-bsi and cc. the tips of catheters were cultured by ma ...	2003	15068127
[relationship between antibacterial activity of aloe and its anthaquinone compounds].	to investigate the relationship between the antibacterial activity of aloe and its contents of anthaquinone compounds, measure and compale antibacterial activities of aloin and aloe-emodin, and analyse the effect of glycoside on the antibacterial activity of aloin.	2003	15615409
structural studies on the lipopolysaccharide core of proteus ox strains used in weil-felix test: a mass spectrometric approach.	the core region of the lipopolysaccharides of proteus group ox bacteria, which are used as antigens in weil-felix test for serodiagnosis of rickettsiosis, were studied by chemical degradations in combination with esi ftms, including infrared multi-photon dissociation (irmpd) ms/ms and capillary skimmer dissociation. structural variants of the inner core region were found to be the same as in proteus non-ox strains that have been studied earlier. the outer core region has essentially the same str ...	2003	14670728
bioassay screening of amazonian plants.	the purpose of this study was to evaluate several biological activities of thirty plant extracts collected in the north west amazon (ecuador). some of these plants are being used for their reputed medicinal properties by the natives of this region.	2003	14619457
separation of glutathione transferase subunits from proteus vulgaris by two-dimensional gel electrophoresis.	cytosolic glutathione transferases of proteus vulgaris were purified by affinity chromatography and characterized by two-dimensional gel electrophoresis. four different subunits were identified, and each subunit contained a different molecular mass, ranging from 26.2 kda to 28.5 kda; a different pi value, ranging from 8.2 to 9.4; and a different amount of protein fraction, ranging from 10% to 56%. all four subunits existed as basic proteins (pi > 7.0). from these results, we concluded that multi ...	2003	14629019
vesical calculi with unrepaired vesicovaginal fistula: a clinical appraisal of an uncommon association.	primary vesical calculi are uncommon in patients with vesicovaginal fistula (vvf). we retrospectively analyzed 19 such cases and present our experience with the management of this condition.	2003	14634380
septicemia caused by retained pacemaker lead tip.		2003	14693331
antimicrobial activity of gymnema sylvestre leaf extract.	the ethanolic extract of gymnema sylvestre leaves demonstrated antimicrobial activity against bacillus pumilis, b. subtilis, pseudomonas aeruginosa and staphylococcus aureus and inactivity against proteus vulgaris and escherichia coli.	2003	14630178
role of arginine 226 in the mechanism of tryptophan indole-lyase from proteus vulgaris.	in the spatial structure of tryptophanase from proteus vulgaris the guanidinium group of arginine 226 forms a salt bridge with the 3;-oxygen atom of the coenzyme. the replacement of arginine 226 with alanine using site-directed mutagenesis reduced the affinity of the coenzyme for the protein by one order of magnitude compared to the wild-type enzyme. the catalytic activity of the mutant enzyme in the reaction with l-tryptophan was reduced 10(5)-fold compared to the wild-type enzyme. the rates of ...	2003	14640959
differential regulation of the proteus mirabilis urease gene cluster by urer and h-ns.	proteus mirabilis, a cause of catheter-associated urinary tract infection, relies on several virulence factors to colonize the urinary tract. among these, urease contributes to the development of urinary stones resulting from the increase in local ph due to urease-mediated hydrolysis of urea to nh(3) and co(2). urer, an arac-like transcriptional activator, activates transcription of the genes encoding the urease subunits and accessory proteins (uredabcefg) in the presence of urea. urer also init ...	2003	14663072
temporomandibular joint involvement in malignant external otitis.	the purpose of this study was to present 6 patients with malignant external otitis (meo) that resulted in temporomandibular joint (tmj) involvement and to discuss the incidence, clinical presentation, and treatment modalities.	2003	14561963
relationship between fluoroquinolone use and changes in susceptibility to fluoroquinolones of selected pathogens in 10 united states teaching hospitals, 1991-2000.	we retrospectively examined the relationship between fluoroquinolone use and the susceptibilities of 11 bacterial pathogens to fluoroquinolones in 10 us teaching hospitals from 1991 through 2000. statistical significance was determined by 2-way analysis of variance, with the number of isolates tested each year as a weighting factor. the analysis of baseline-to-end point change in the percentage of susceptibility and the slope of the regression line (trend line) for logit percentage of susceptibi ...	2003	14689346
[comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2001). i. susceptibility distribution].	the bacterial strains isolated from patients diagnosed as having urinary tract infections (utis) in 10 institutions in japan were supplied between the period of september and december 2001. then, the susceptibilities of them to a variety of antimicrobial agents were investigated. the number of them were 496 strains. the breakdown of these strains was gram-positive bacteria as 29.6% and gram-negative bacteria as 70.4%. susceptibilities of these bacteria to antimicrobial agents were as follows; ag ...	2003	14692378
[post-marketing surveillance of antibacterial activities of cefozopran against various clinical isolates--ii. gram-negative bacteria].	as a post-marketing surveillance, the in vitro antibacterial activities of cefozopran (czop), an agent of cephems, against various clinical isolates were yearly evaluated and compared with those of other cephems, oxacephems, carbapenems, monobactams, and penicillins. changes in czop susceptibility among bacteria were also evaluated with the bacterial resistance ratio calculated from the breakpoint mic. twenty-five species (4,154 strains) of gram-negative bacteria were isolated from the clinical ...	2003	14692381
structure of the o-polysaccharide leads to classification of proteus penneri 31 in proteus serogroup o19.	o-polysaccharide was obtained by mild acid degradation of the lipopolysaccharide (lps) of proteus penneri strain 31. sugar and methylation analyses along with nmr spectroscopic studies, including 2d 1h,1h cosy, tocsy, roesy, 1h,13c and 1h,31p hmqc experiments, demonstrated the following structure of the polysaccharide: [carbohydrate structure: see text] where fucnac is 2-acetamido-2,6-dideoxygalactose and etnp is 2-aminoethyl phosphate. the polysaccharide studied has the same carbohydrate backbo ...	2003	14556999
why are foley catheters so vulnerable to encrustation and blockage by crystalline bacterial biofilm?	many patients undergoing long-term bladder catheterisation experience blockage and encrustation of their catheters. the problem stems from infection by urease producing bacteria, particularly proteus mirabilis. bacterial biofilms colonise the catheters, the activity of urease raises the ph and induces the deposition of calcium and magnesium phosphate crystals. in this study, a laboratory model of the catheterised bladder has been used to examine the early stages in the formation of the crystalli ...	2003	14574534
[urinary tract infection in institutionalized elderly patients. incidence of bacterial resistance and risk factors].	the goal of the present work was to study urinary tract infections (uti) in a sociosanitary center in order to characterize etiology, define sensitivity profiles, and study associations between these profiles and various clinical parameters.	2003	14576919
the antimicrobial activity of extracts of the lichen cetraria aculeata and its protolichesterinic acid constituent.	in this study, the antimicrobial activity of the acetone, diethyl ether and ethanol extracts of the lichen cetraria aculeata has been investigated. the extracts were tested against twelve bacteria and eight fungi and found active against escherichia coli, staphylococcus aureus, aeromonas hydrophila, proteus vulgaris, streptococcus faecalis, bacillus cereus, bacillus subtilis, pseudomonas aeruginosa, listeria monocytogenes. no antimicrobial activity against the fungi was detected. it was determin ...	2003	14713164
polyhalogenated benzo- and naphthoquinones are potent inhibitors of plant and bacterial ureases.	polyhalogenated benzo- and naphthoquinones were found to be potent inhibitors of pure ureases from bacillus pasteurii and canavalia ensiformis. they also inhibited ureases in whole cells of helicobacter pylori, klebsiella oxytoca and proteus mirabilis. inhibition was non-competitive with k(i) values in the micromolar range or below. inhibition was irreversible as shown by equilibrium dialysis. inhibitory power decreased considerably when halogens were replaced by -oh, -cn, alkoxy or alkyl groups ...	2003	14644444
proteus mirabilis and rheumatoid arthritis: no association with the disease.	proteus mirabilis (pm) is implicated in different studies in the pathogenesis of rheumatoid arthritis (ra) because of the structural homogeneity of its haemolysin b precursor with eqrraa sequences in drb 1 haplotype. the aim of the study was to compare the levels of antibodies specific to pm in the sera of patients with ra and healthy controls in our population. serum samples from 78 consecutive ra patients and 75 healthy controls were analysed for the presence of igg isotype and total immunoglo ...	2003	14576988
proteus mirabilis fimbriae (pmf) are important for both bladder and kidney colonization in mice.	proteus mirabilis expresses different types of fimbriae simultaneously. several fimbrial types have been described and their role in the colonization of the urinary tract is under study. previously, p. mirabilis fimbriae (pmf) have been shown to be associated with bacterial colonization of the lower urinary tract but not of the kidneys. in this study, a pmfa mutant was generated and used in several in vivo and in vitro studies. two different urinary tract infection models in the mouse and two in ...	2003	14600235
structural studies of proteus mirabilis catalase in its ground state, oxidized state and in complex with formic acid.	the structure of proteus mirabilis catalase in complex with an inhibitor, formic acid, has been solved at 2.3 a resolution. formic acid is a key ligand of catalase because of its ability to react with the ferric enzyme, giving a high-spin iron complex. alternatively, it can react with two transient oxidized intermediates of the enzymatic mechanism, compounds i and ii. in this work, the structures of native p. mirabilis catalase (pmc) and compound i have also been determined at high resolution (2 ...	2003	14646074
antimicrobial sensitivity pattern of organisms causing urinary tract infection in children with sickle cell anaemia in ibadan, nigeria.	as part of a larger project on childhood urinary tract infection, antimicrobial sensitivity tests were carried out on the bacterial isolates from the urine of febrile children seen at the university college hospital, ibadan, nigeria.	2003	14529216
soil microbial populations, community composition, and activity as affected by repeated applications of hog and cattle manure in eastern saskatchewan.	a field site near humboldt, saskatchewan, was annually treated with hog or cattle manure and cropped to canola, spring wheat, barley, and canola from 1997 to 2000. during each growing season, soil was analyzed for microbial populations in terms of activity and community structure, and crops were assessed for root rot and foliar diseases. microbial activity in soils treated with cattle manure was higher than in soils treated with hog manure or urea. similarly, nitrous oxide emissions from soil in ...	2003	14608420
endoscopic treatment in a patient with obstructive jaundice caused by pancreatic pseudocyst.	we report a case of chronic alcoholic pancreatitis with obstructive jaundice due to compression of the common bile duct by pancreatic pseudocyst. ultrasonography and computed tomographic scan on admission demonstrated an 8 cm cystic lesion located at the head of the pancreas. endoscopic retrograde cholangiopancreatography (ercp) revealed a segment of narrowing at the distal common bile duct which was compressed by the pancreatic pseudocyst. communication between the cyst and pancreatic duct was ...	2003	14649681
[antibacterial activity of pure cultures of cyanobacteria and algae].	pure cultures of microcystis aeruginosa, platymonas viridis and nephrochloris salina have been grown on the media with different nitrogen and phosphorus content. their supernatants and pellets, as well as lipid complex, terpene fraction and some its components from m. aeruginosa had selective antibacterial characteristics. the increase of nitrogen content in the medium correlated with the intensification (m. aeruginosa, n. salina) or conservation (p. viridis) of bactericidal activity. the pellet ...	2003	14618789
fusarium infections in burn patients: a case report and review of the literature.	fusarium species, or saprophytic molds, are important plant pathogens and recognized as agents of human mycotic infections. frequently superficial, deep-tissue involvement, and dissemination occurs in immunocompromised hosts with hematologic malignancies, aplastic anemia, and chemotherapy treatment. presented in this work is a burn patient with a fatal disseminated infection in addition to a review of the literature. a 40-year-old white male acquired a 73% grease scald injury at work. his hospit ...	2003	14501396
beta-lactamase stability of faropenem.	faropenem (far) is an orally available member of the penem class unique among carbapenems and other available beta-lactams. this study compared far to cephalosporins and imipenem with respect to beta-lactamase (bla) stability and emergence of resistance to staphylococcus aureus and escherichia coli. bla stability was studied using enzyme preparations from sonicated/centrifuged 24-hour cultures of e. coli, enterobacter cloacae, proteus vulgaris, providencia rettgeri, klebsiella pneumoniae, s. aur ...	2003	14504433
in vitro susceptibilities of gram-negative bacteria isolated from hospitalized patients in four european countries, canada, and the united states in 2000-2001 to expanded-spectrum cephalosporins and comparator antimicrobials: implications for therapy.	access to current antimicrobial agent surveillance data is an important prerequisite for the optimal management of patients with hospital-acquired infections. the present study used data collected in 2000 to 2001 from 670 laboratories in europe (france, germany, italy, and spain), canada, and the united states to report on the in vitro activities of ceftriaxone, cefotaxime, and comparative agents against >125,000 isolates of gram-negative bacteria from hospitalized patients. all but two isolates ...	2003	14506014
proteus syndrome with gingival hyperplasia.		2003	14521702
[brain abscesses after extracranial infections of the head and neck area].	the authors report on 20 immunocompetent patients with brain abscess after 12 cases of middle ear, seven tooth and a single frontal sinus infection. the clinical aspects, hematochemical and microbiological data, the role of imaging diagnostics (ct, mr) and the type of treatment are analysed. neurosurgery was performed on 17 patients (85%), eight of whom subsequently underwent evacuation of the primary source of infection (four mastoidectomies, two timpanoplasties, two tooth extractions). mastoid ...	2003	14523535
role of aspartate-133 and histidine-458 in the mechanism of tryptophan indole-lyase from proteus vulgaris.	tryptophan indole-lyase (trpase) from proteus vulgaris is a pyridoxal 5'-phosphate dependent enzyme that catalyzes the reversible hydrolytic cleavage of l-trp to yield indole and ammonium pyruvate. asp-133 and his-458 are strictly conserved in all sequences of trpase, and they are located in the proposed substrate-binding region of trpase. these residues were mutated to alanine to probe their role in substrate binding and catalysis. d133a mutant trpase has no measurable activity with l-trp as su ...	2003	14503866
antimicrobial activity of some 2- and 3-pyridinyl-1h-benzimidazoles and their feiii, cuii, znii, and agi complexes.	2-(2-pyridinyl)- (li), 2-(6-methyl-2-pyridinyl)- (lii), 2-(6-methyl-2-pyridinyl)-5-methyl-(liii), 2-(3-pyridinyl)- (liv), 2-(3-pyridinyl)-5-methyl-1h-benzimidazoles (lv) and their complexes with fe(no3)3, cu(no3)2, zn(no3)2, and agno3 were synthesized and antibacterial activity of the compounds was tested toward staphylococcus aureus, staphylococcus epidermidis, escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, salmonella typhi, shigella flexneri, proteus mirabilis and antifungal ...	2003	14533478
effect of nacl concentration on the survival and growth of coliforms in raw seasoned sausages.		2003	14535413
are infections due to resistant pathogens associated with a worse outcome in critically ill patients?	to evaluate the outcome of critically ill patients infected with antimicrobial resistant microorganisms, and to analyse the factors involved in the development of antimicrobial resistance.	2003	14556755
staghorn calculus in renal allograft presenting as acute renal failure.	urolithiasis is a rare complication in renal transplant recipients. we report a case of a staghorn calculus occurring in renal allograft, presenting as anuric renal failure with gram-negative sepsis.	2003	14508619
immunodetection and intracellular localization of caldesmon-like proteins in amoeba proteus.	caldesmon immunoanalogues were detected in amoeba proteus cell homogenates by the western blot technique. three immunoreactive bands were recognized by polyclonal antibodies against the whole molecule of chicken gizzard caldesmon as well as by a monoclonal antibody against its c-terminal domain: one major and two minor bands corresponding to proteins with apparent molecular masses of 150, 69, and 60 kda. the presence of caldesmon-like protein(s) in amoebae was revealed as well in single cells af ...	2003	14513313
[yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--ii. gram-negative bacteria].	the in vitro antibacterial activities of cefozopran (czop), an agent of cephems, against various clinical isolates obtained between 1996 and 2001 were yearly evaluated and compared with those of other cephems, oxacephems and carbapenems. a total of 3,245 strains in 32 species of gram-negative bacteria were isolated from the clinical materials annually collected from january to december, and consisted of moraxella subgenus branhamella catarrhalis, escherichia coli, citrobacter freundii, citrobact ...	2003	14567255
structure of the n-acetyl-l-rhamnosamine-containing o-polysaccharide of proteus vulgaris tg 155 from a new proteus serogroup, o55.	the o-polysaccharide of the lipopolysaccharide (lps) of proteus vulgaris tg 155 was found to contain 2-acetamido-2,6-dideoxy-l-mannose (n-acetyl-l-rhamnosamine, l-rhanac), a monosaccharide that occurs rarely in nature. the following structure of the o-polysaccharide was established by nmr spectroscopy, including 2d cosy, tocsy, roesy and 1h,13c hsqc experiments, along with chemical methods: [carbohydrate structure in text] rabbit polyclonal o-antiserum against p. vulgaris tg 155 reacted with bot ...	2003	14499576
proteus mirabilis and rheumatoid arthritis: no association with the disease.	proteus mirabilis(pm) is implicated in different studies in the pathogenesis of rheumatoid arthritis (ra) because of the structural homogeneity of its haemolysin b precursor with eqrraa sequences in drb 1 haplotype. the aim of the study was to compare the levels of antibodies specific to pm in the sera of patients with ra and healthy controls in our population. serum samples from 78 consecutive ra patients and 75 healthy controls were analysed for the presence of igg isotype and total immunoglob ...	2003	14505214
susceptibility trends in bacteraemias: analyses of 7544 patient-unique bacteraemic episodes spanning 11 years (1990-2000).	the aim of the present study was to design more accurate tools for the selection of appropriate antimicrobial therapy for hospitalized patients with suspected sepsis. we created a large database comprising data on all patient-unique blood cultures obtained over an 11 year period (1 january, 1990 through 31 december, 2000). improved statistical tools were applied to assess the trends in in vitro activity of individual antibiotic agents against various bacteria over time, and to calculate suscepti ...	2003	14572487
structure of the o-polysaccharide of a serologically separate strain of proteus mirabilis, tg 332, from a new proposed proteus serogroup o50.	the o-polysaccharide was obtained by mild acid degradation of the lipopolysaccharide of proteus mirabilis tg 332 strain. the following structure of the o-polysaccharide was determined by chemical methods along with nmr spectroscopy, including 2d cosy, tocsy, roesy and 1h, 13c hmqc experiments: [see equation in text]. the o-polysaccharide studied has a unique structure among proteus o-antigens. accordingly, p. mirabilis tg 332 is serologically separate, and we propose to classify this strain into ...	2003	14505878
proteus syndrome.	a 34-year-old male patient was referred with a recalcitrant leg ulcer overlying an extensive vascular malformation, which had led several times to septic soft tissue infections. during his infancy he had been diagnosed to have klippel-trenaunay syndrome. clinical examination revealed asymmetric hypertrophy of the lower extremities, an extensive portwine stain on the more severely affected left limb as well as prominent venous varicosities of both legs. hands and feet showed striking cerebriform ...	2003	14524037
urinary tract infections in south croatia: aetiology and antimicrobial resistance.	the aim of this study was to determine the distribution of uropathogens isolated from outpatients living in south croatia and the in vitro susceptibility of these organisms to antimicrobial agents. of 5080 enrolled uropathogen isolates, 82.28% isolates were gram-negative, the most frequent isolates being escherichia coli (62.62%), enterococci (10.18%), proteus mirabilis (5.31%), streptococcus agalactiae (3.84%), staphylococcus spp. (3.70%), pseudomonas spp. (3.46%), klebsiella spp. (2.38%). the ...	2003	14527773