Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| stability of fluorescent antibody conjugates stored under various conditions. | two experiments were carried out to determine the stability of fluorescent antibody conjugates. in experiment 1, francisella tularemia conjugates in the lyophilized state retained their original staining titer for 1,294 days when stored at 25, 4 to 5, and -20 c; at 37 c the conjugates were stable for at least 65 days. in the liquid state at ph 7.4 and 8.0 these conjugates were stable for 1,294 days at 4 to 5 and -20 c, whereas those stored at 25 c remained stable through days 473 and 160 of stor ... | 1976 | 3516 |
| protein synthesis in zinc deficient rats during tularemia. | the effect of zinc deficiency on protein synthesis in rats during tularemia was studied. five weeks prior to infection with the live vaccine strain of francisella tularensis, rats had been assigned to one of three dietary groups: zinc deficient (-zn), pair-fed (pf) or ad libitum (al). within 4 weeks, zinc deficiency manifested itself by diminished growth rate, decreased serum and liver zinc concentrations and alopecia. by 18 hour post infection, rats of all groups were febrile and exhibited an i ... | 1976 | 58980 |
| tularemia in a mule deer. | a case of tularemia was confirmed in a 51-year-old man who acquired the disease from a mule deer, odocoileus hemionus. francisella tularensis was isolated from bone marrow of the deer carcass. | 1976 | 16498895 |
| induced metabolic sequelae of tularemia in the rat: correlation with tissue damage. | serum and liver zinc concentration, amino acid uptake by liver, seromucoid content, and alpha2-macrofetoprotein production were measured in vaccinated as well as nonimmune rats exposed to either virulent (schu s4) or attenuated (lvs) strains of francisella tularensi. it appears that liver damage (pyogranulomatous lesions) must occur before there is any alteration in the above variables. the presence of bacteria in the liver is not of itself sufficient to lead to the onset of systemic, induced me ... | 1975 | 51592 |
| [discovery of tularemia epizootics by way of detecting the tularemia microbe antigen in the droppings of predatory birds]. | 1975 | 128957 | |
| [effects of intradermally administered tularin sevac on the titre of slow agglutination reaction with the francisella tularensis antigen (author's transl)]. | 1975 | 130981 | |
| the human placental villitides: a review of chronic intrauterine infection. | 1975 | 172296 | |
| [an experimental study of mixed tularemia and omsk hemorrhagic fever infection in muskrats]. | musk-rats were infected simultaneously and at three-day interval with tularemia and omsk hemorrhagic fever (ohf); the course of this mixed infection under the mentioned conditions were studied. virological, microbiological and morphological data indicated that infection of musk-rats with ohf and tularemia caused development of mixed infection in them. a more severe course of mixed infection was associated with enhanced vascular affections caused by the action of the ohf virus. an inhibition of t ... | 1975 | 175620 |
| [changes in the antibacterial effects of organs and tissues of ornithodoros papillipes birula ticks]. | 1975 | 234572 | |
| phagocytosis of francisella tularensis by rhesus monkey peripheral leukocytes. | phagocytosis of francisella tularensis by rhesus monkey peripheral neutrophils (pmn, was assessed by autoradiography, electron microscopy, and biochemical techniques. pmn, in contrast to mononuclear phagocytes, were unable to phagocytize f. tularensis in vitro in the absence of immune serum. it is postulated that in the nonimmune host the innate inability of pmn to phagocytize f. tularensis deletes one of the possible mechanisms of host defense to bacterial infection and thus permits the early d ... | 1975 | 234911 |
| temporal appearance of opsonizing antibody to francisella tularensis: detection by a radiometabolic assay. | the burst in oxidative metabolism that is mediated through activation of the hexose monophosphate shunt and accompanies particle ingestion by polymorphonuclear leukocytes was used as the indicator in an in vitro radiometabolic assay for detection of specific opsonizing antibody to francisella tularensis. release of 14co2 from radiolabeled glucose was increased significantly when specific immune serum added to suspensions of monkey polymorphonuclear leukocytes and f. tularensis. with this method, ... | 1975 | 234915 |
| [sialic acid in f. tularensis and f. novicida antigens]. | sialic acid was revealed in the antigens of virulent (503/830 and schu) and vaccine (schu-attenuated and 15-reduced) strains of f. tularensis and also in the antigens of f. novicida isolated by the treatment with trichloracetic acid, by the thiobarbiturate method of warren. its content depended on the culture virulence. sialic acid was absent in the antigens of avirulent strains of the causative agent of tularemia (503-attenuated, 15-attenuated and 21/400), but, in difference from the virulent s ... | 1975 | 235820 |
| [the possibility of predicting the degree of plasmacyte reaction in response to administration of soluble antigen to mice]. | the work is devoted to the mathematical description of the accumulation of plasma cells in the spleen of cba mice immunized intraperitoneally. a dependence between the dynamics of the soluble antigen concentration in the blood and the plasmocytic reaction in the spleen was confirmed under experimental conditions. index a was suggested for detection of a change from the antigenic function to the accumulation of plasma cells. the mean values of index a were used to compare the calculated values of ... | 1975 | 235822 |
| tularaemia in the rat. i. the cellular basis on host resistance to infection. | rats infected with the live vaccine strain (lvs) of francisella tularensis develop in vivo and in vitro evidence of cellular hypersensitivity and a concomitant state of cellular resistance to infection. they key role of sensitized lymphocytes in cellular resistance was domonstrated in transfer experiments. using this technique, it was shown that thoracic duct lymphocytes from francisella immune donors conferred specific antimicrobial resistance on normal recipients, whereas antiserum afforded no ... | 1975 | 236983 |
| the mediator of cellular immunity. x. interaction of macrophages and specifically sensitized lymphocytes. | 1975 | 237635 | |
| biochemical and immunological properties of ribonucleic acid-rich extracts from francisella tularensis. | ribonucleic acid (rna)-rich extracts derived from the attenuated strain of francisella tularensis (strain lvs) protected swiss mice against lethal challenge with f. tularensis strain 425 but not against strain schu s4. no killed preparation, including an rna-rich extract from schu s4 itself, offered protection against strain schu s4 in contrast to the high level of protection offered against this strain by vaccination with live strain lvs. the protective activity observed against strain 425 was ... | 1975 | 237834 |
| relationship of serum beta-glucuronidase and lysozyme to pathogenesis of tularemia in immune and nonimmune rats. | a temporal study is reported of the febrile responses, tissue bacterial contents, and serum concentration of the lysosomal enzymes, beta-glucuronidase and lysozyme, in nonimmune rats inoculated with virulent or attenuated strains of francisella tularensis, and in immune rats challenged with either a high or low dose of virulent organisms. the level of serum beta-glucuronidase appears to be an indicator of hepatocyte damage, whereas serum lysozyme correlates with the appearance, frequency, and se ... | 1975 | 237835 |
| chronic shedding tularemia nephritis in rodents: possible relation to occurrence of francisella tularensis in lotic waters. | contamination of streams by francisella tularensis, a fastidious pathogen, was discovered by miller in russia. subsequently that contamination was found to be the source of extensive human outbreaks, and to occur as well in north america. circumstantial evidence supports a hypothesis that infected voles are responsible for the contamination, but when freshly isolated f. tularensis palaearctica is inoculated parenterally, only acute illness and death result whereas long-term contamination of stre ... | 1975 | 239255 |
| [isolation of the causative agent of tularemia from siberian lemmings in eastern taymyr]. | the authors present the results of bacteriological and serological study for tularemia of 498 lemmings caught in taimyr. positive results were revealed in 4 out of 98 sera examined in the indirect hemagglutination test. in carrying out 67 biological tests on albino mice there were isolated for the first time in the soviet union 6 cultures of the causative agent of tularemia from the spleen of lemmings. by morphological, cultural and virulent properties the cultures obtained failed to differ from ... | 1975 | 239505 |
| [nitrofurantoin-test for the differentiation of bordetella bronchiseptica (author's transl)]. | bordetella bronchiseptica is primarily resistant against nitrofurantoin (mic greater than 200 mug/ml), and this feature can be used for the differentiation of the organism from other gram-negative coccobacteria. nitrofurantoin paper disks (300 mug) failed to affect the growth of 150 strains of b. bronchiseptica isolated from different animal hosts, but they produced marked inhibition zones in the cultures of the followingspecies: pasteurella multocida, pasteurella pneumotropica, pasteurella haem ... | 1975 | 809944 |
| [cultivation of f. tularensis in developing chick embryos]. | in cultivation of the causative agent of tularemia in the organism of chick embryos (8-10 days of incubation) it was found that the virulent strains multiplied intensively in the yolk sacs causing the death of the embryos on the 3rd-4th day after the infection; as to the virulent strains-they were only preserved in the embryos. the period of death of the embryos and the accumulation of bacteria depended on the strain virulence. no differences in the anatomical structure of the cells belonging to ... | 1975 | 766523 |
| common enterobacterial antigen in yersinia enterocolitica. | production of the common enterobacterial antigen (ca) by strains of yersinia enterocolitica (y.e.) serotypes 3 and 9 (winblad), by strains of 5 different y.e. serogroups (wauters) and various other bacteria was examined. antibody against ca was raised by immunization of rabbits with e. coli o 14. extract prepared from s. typhimurium was used for the sensitization of sheep erythrocytes with ca. absorption and haemagglutination inhibition experiments showed that ca could be detected in heat extrac ... | 1975 | 1098394 |
| one-half century of tularemia in florida. | 1975 | 1099166 | |
| [detection of the causative agent of tularemia in the organs of animals in the early stages of development of the infection]. | a study was made of a possibility of detection of the causative agent of tularemia in the organism of albino mice at early stages of development of the infection after subcutaneous infection with 1, 10 and 100 microbial cells of strains no. 503/834 (holarctic race) and schu (nearctic race). the following examinations were made: cultivation on nutrient media, immunofluorescent study, the antibody neutralization test and the passive hemagglutination test with erythrocytic diagnostic agents. the mi ... | 1975 | 1108514 |
| [use of the immunofluorescence method to detect the causative agent of tularemia in developing chick embryos]. | there was shown a possibility of using the immunofluorescent method for detection of the causative agent of tularemia in the developing chick embryos, infected with the virulent strains 503 (holoarctic race) and schu (nonarctic race). the greatest accumulation of bacteria was revealed in the yolk sacs, and the least--in the chorionallantoic fliud; the greatest accumulation of bacteria was observed on the 3rd--4th days after the infection. in infection with various doses of the causative agent--f ... | 1975 | 1108521 |
| [phagocytic activity of the neutrophils in tularemia in animals with varying infective sensitivity]. | a study was made of the ingestive capacity of blood neutrophils; there were revealed no significant differences in the intact animals with a different infectious sensitivity to tularemia. with the development of infection the ingestive activity of leukocytes increased in the infected highly sensitive animals, but the digestive function was not manifest. in albino rats (with a low sensitivity to tularemia) the disease induced an intensification of the ingestive and the manifestation of the digest ... | 1975 | 1108522 |
| cyclic kinetics and mathematical expression of the primary immune response to soluble antigen. vi. the possibility of prediction of plasma cell reaction in the spleen of mice immunized with soluble antigen. | a mathematical expression of the accumulation of the plasma cells in the spleen of cba mice immunized intraperitoneally is presented. the dependence of the plasma cell reaction in the spleen on the kinetics of antigen concentration in the blood was confirmed. for the transition from antigen to plasma cells, index a was proposed. the mean values of index a were used for comparison of the calculated and experimental values of the plasma cell reaction and the recorded differences were not great. in ... | 1975 | 1176044 |
| a microbiologic study of the urban gray squirrel. | bacteriologic, virologic, and serologic examinations were conducted on 180 urban gray squirrels (sciurus carolinensis) during a 1-year period in a metropolitan area. evidence was not found of infections with leptospires, enteric or other bacteria, rickettsial agents, francisella tularensis, or arthropod-borne viruses. the squirrels were remarkably free of evidence of bacterial or viral infections of importance to man and lower animals. | 1975 | 1176356 |
| pathogenesis of tularemia in immune and nonimmune rats. | pathogenesis of tularemia in nonimmune rats given (intraperitoneal inoculation) virulent strain (schu s4) or vaccinal strain (lvs) of francisella tularensis and in immune rats given schu s4 is described. both lvs and schu s4 caused pyogranulomas in liver and spleen of nonimmune rats. nonimmune rats given 10(4) schu s4 organisms did not survive beyond 72 hours, but immune rats given challenge inoculum of 10(8) schu s4 organisms developed lesions and survived. larger doses of lvs resulted in earli ... | 1975 | 1190592 |
| stimulation of human lymphocytes by a vaccine strain of francisella tularensis. | an immune response to francisella tularensis was demonstrated in man by the lymphocyte stimulation test. peripheral blood lymphocytes were obtained from 26 individuals vaccinated with a viable tularemia vaccine, from 29 unvaccinated individuals, and from two patients who had recently undergone tularemia. the lymphocytes were incubated in the presence of various dilutions of heat-killed bacteria of the vaccine strain. the bacteria induced a deoxyribonucleic acid synthesis in the lymphocytes from ... | 1975 | 1193733 |
| murine model for study of cell-mediated immunity: protection against death from fully virulent francisella tularensis infection. | to assess cell-mediated immunity in terms of host protection, an experimental model was developed in which passively transferred spleen cells from immunized akr/j mice enabled nonimmume syngeneic recipients to survive an otherwise fatal infection with fully virulent francisella tularensis. donor immunization was achieved by administering live attenuted tularemia vaccine and, subsequently, the virulent streptomycin-sensitive schu s4 strain of f. tularensis. at selected intervals after immunizatio ... | 1975 | 1193736 |
| [further study of the sensitivity to erythromycin of strains of the causative agent of tularemia from different geographical sites]. | 1975 | 1199584 | |
| [morphology of the temperate plague phages 1701 and 1710 and their mutants]. | a study was made of the morphology of plague moderate bacteriophages 1701, 1710 and their mutants 1701-1 and 1710-1. the phages proved to be morphologically identical, were referred to group 5, and were identical to the moderate plague h-phages; when confronted to the commonness of the serological properties and a number of other signs this indicated their affinity. | 1975 | 1210893 |
| [detection of dissociation of tularemia microbe cultures by the method of staining of colonies]. | 1974 | 4139347 | |
| zoonotic potential (rocky mountain spotted fever aed tularemia) in the tennessee valley region. ii. prevalence of rickettsia rickettsi and francisella tularensis in mammals and ticks from land between the lakes. | 1974 | 4204021 | |
| zoonotic potential (rocky mountain spotted fever and tularemia) in the tennessee valley region. i. ecologic studies of ticks infesting mammals in land between the lakes. | 1974 | 4204030 | |
| microagglutination test for detecting and measuring serum agglutinins of francisella tularensis. | a microagglutination method utilizing stained antigen for detecting and measuring serum agglutinins against francisella tularensis is described. the microagglutination and standard tube agglutination techniques were demonstrated to be comparable in sensitivity and specificity. advantages of the micro method are rapidity and ease of performance, economy of reagents and, in particular, ease of interpreting specific reactivity. | 1974 | 4129476 |
| the mediator of cellular immunity. vii. localization of sensitized lymphocytes in inflammatory exudates. | peritoneal exudates induced in rats infected with listeria monocytogenes contain sensitized lymphocytes which can protect normal recipients against a listeria challenge. the protective cells arise in lymphoid tissue remote from the peritoneal cavity. those formed in the caudal lymph nodes of subcutaneously infected rats are delivered to the thoracic duct and hence to the blood from where they are drawn into exudates. immunoblasts are the most immature members of this protective cell population a ... | 1974 | 4208417 |
| [rapid processing of material for the antibody neutralization test in case of detection of antigen of tularemia and f-1 plague]. | 1974 | 4214964 | |
| vaccine potencies of the live vaccine strain of francisella tularensis and isolated bacterial components. | 1974 | 4215444 | |
| [p-antigen of the causative agent of tularemia]. | 1974 | 4218034 | |
| [plague, tularemia and anthrax immunization with associated di- and trivaccines using a jet injector. i]. | 1974 | 4218042 | |
| further studies on tularemia in alaska: human tularemia. | 1974 | 4434260 | |
| further studies on tularemia in alaska: virulence and biochemical characteristics of indigenous strains. | 1974 | 4434261 | |
| [tularemia laboratory infection]. | 1974 | 4445529 | |
| [evaluation of tularemia vaccine strains in experiments on rabbits]. | 1974 | 4454858 | |
| [attempts at growing francisella tularensis in cell cultures in vitro]. | 1974 | 4471744 | |
| [experimental mixed infection in muskrats (omsk hemorrhagic fever and tularemia)]. | 1974 | 4613000 | |
| [experimental production of specific fluorescent tularemia serum using a non-virulent strain]. | 1974 | 4614554 | |
| oysters: retention and excretion of three types of human waterborne disease bacteria. | 1974 | 4586734 | |
| [use of the fluorescent antibody technic for detection of the agent of tularemia in the organs of experimentally infected animals]. | 1973 | 4595602 | |
| survival of airborne pasteurella tularensis at different atmospheric temperatures. | the aerosol survival, recovery, and death rate of pasteurella tularensis schu s5 disseminated in particle sizes of 1 to 5 mum were significantly affected by air temperature. the highest aerosol recovery of viable p. tularensis was observed within -7 and 3 c; the recovery decreased significantly below and above this temperature range. the death rate of airborne p. tularensis was not significantly influenced by an increase in temperature from -40 to 24 c. however, a progressive increase in atmosph ... | 1973 | 4633423 |
| first detection of tularaemia in domestic and wild mammals in iran. | during a study on the ecology of small-mammal-borne infections in iran, over 4 600 wild mammals were collected at 47 localities. attempts were made to isolate francisella tularensis from the spleens of 3 548 of these animals. all were found to be negative. in addition, sera from 200 sheep and cattle and from 39 wild mammals were tested: 8 sheep, 3 oxen, and 1 hedgehog showed evidence of recent infection. this is the first report of tularaemia in iran. the relationship of these findings to the po ... | 1973 | 4548386 |
| tularaemic pneumonia: pathogenesis of the aerosol-induced disease in monkeys. | 1973 | 4200656 | |
| [study of the toxicity of f. tularensis following the action of ionizing irradiation]. | 1973 | 4711422 | |
| tularemia epidemic associated with the deerfly. | 1973 | 4740907 | |
| tularemia. | 1973 | 4740911 | |
| effects of hypobaric hyperoxia on the development and activity of immune spleen cells. | 1973 | 4744245 | |
| [determination of fibrinolytic activity of the causative agent of tularemia]. | 1973 | 4785009 | |
| [change in the properties of the causative agent of tularemia due to erythromycin]. | 1973 | 4785841 | |
| afghan hedgehog, a new reservoir of tularemia. | 1973 | 4801900 | |
| [history of the study of the causative agent of tularemia]. | 1973 | 4585673 | |
| [ornithonyssus bacoti mites as pest on a farm]. | 1973 | 4133599 | |
| [isolation of the a-antigen of the tularemia microbe]. | 1973 | 4205255 | |
| [the physico-chemical properties and allergenic activity of peptides of various species of bacteria]. | 1973 | 4205258 | |
| [submicroscopic structure of the bacterial cell wall (review of the literature)]. | 1973 | 4206610 | |
| human infections with francisella tularensis in norway. development of a serological screening test. | 1972 | 4503972 | |
| aerosol survival of pasteurella tularensis and the influence of relative humidity. | the aerosol survival in air was determined for pasteurella tularensis live vaccine strain (lvs) as a function of relative humidity (rh). three different preparations of bacteria were used: (i) liquid suspension of p. tularensis lvs in spent culture medium; (ii) powders of p. tularensis lvs freeze-dried in spent culture fluid; (iii) p. tularensis lvs freeze-dried in spent culture fluid and then reconstituted with distilled water and disseminated as a liquid suspension. preparation (i) gave greate ... | 1972 | 4551041 |
| infection-immunity in tularemia: specificity of cellular immunity. | the relationship between hypersensitivity and cellular resistance to infection with facultative intracellular parasites was studied in mice by using infection-immunity in tularemia as a model system. delayed hypersensitivity to antigenic fractions of francisella tularensis was first detected 6 to 7 days after immunization with viable f. tularensis vaccine, at which time immunity against challenge infection developed. both immunity and delayed-type sensitivity reached maximal levels by 9 to 10 da ... | 1972 | 4564560 |
| tularemia: dr. edward francis and his first 23 isolates of francisella tularensis. | 1972 | 4570449 | |
| [experience of a 25-year study of the stability of properties of tularemia vaccine strains]. | 1972 | 4643653 | |
| bacteriological study of a natural focus of tularemia in the lake reserve of srebrna, the silistra region, bulgaria. | 1972 | 4673074 | |
| the antigenic structure of francisella tularensis. i. isolation of the ether antigen and its fractionation. | 1972 | 4624012 | |
| function of the alveolar macrophage in immunity. | 1972 | 4624744 | |
| the antigenic structure of francisella tularensis. ii. fractionation of the ether antigen on cellulose carriers and by gel filtration. | 1972 | 4627016 | |
| methods for the assessment of microbial populations recovered from enclosed aerosols. | 1972 | 4627206 | |
| rapid assays for the detection and determination of sparse populations of bacteria and bacteriophage t7 with radioactively labelled homologous antibodies. | 1972 | 4627207 | |
| pathogenesis of tularemia in monkeys aerogenically exposed to francisella tularensis 425. | the pathogenesis of tularemia was studied in groups of rhesus monkeys (macaca mulatta) that inhaled graded 10-fold doses ranging from 10 through 10(6) organisms of francisella tularensis 425, a strain highly virulent for the white mouse but of reduced virulence for the domestic rabbit. mean incubation periods ranged from 3 to 6 days followed by acute illness lasting 5 to 11 days with subsequent recovery of most animals. the higher inhaled doses resulted in shorter incubation periods, longer and ... | 1972 | 4629251 |
| susceptibility of tularemia bacilli to the antagonistic action of cocci. | 1972 | 4632426 | |
| experimental tularemia in macaca mulatta: relationship of aerosol particle size to the infectivity of airborne pasteurella tularensis. | ninety-six macaca mulatta were exposed to aerosol particles containing pasteurella tularensis. four different aerosols were employed that contained particle size distributions with median diameters of 2.1, 7.5, 12.5, or 24.0 mum. size distributions were calculated only for those particles observed by phase microscope to contain organisms. animals exposed to particles whose median diameters were either 2.1 or 7.5 mum were all infected and showed extensive infection of the lower respiratory tract, ... | 1972 | 4632469 |
| [some characteristics of the metabolism of francisella tularensis media asiatica aikimb]. | 1972 | 5018219 | |
| [biochemical characteristics of tularemia strains from central asia]. | 1972 | 5027035 | |
| [sensitivity of hungarian strains of francisella tularensis to antibiotics]. | 1972 | 5051095 | |
| behavioral effects of infectious diseases: respiratory pasteurella tularensis in man. | 1971 | 5089099 | |
| [presence of amino acid decarboxylases in francisella tularensis]. | 1971 | 5099097 | |
| airborne tularemia in sweden. | 1971 | 5099427 | |
| tularaemia. | 1971 | 5107036 | |
| [study of the immunizing effect of the virulent tularemia strain treated by streptomycin]. | 1971 | 5139456 | |
| aerosol survival of pasteurella tularensis disseminated from the wet and dry states. | the aerosol survival in air and in nitrogen was measured for pasteurella tularensis live vaccine strain, disseminated from the wet and dry states. the results showed that most of the loss of viability occurred in less than 2 min of aerosol age, i.e., a rapid initial decay followed by a much slower secondary decay. in nitrogen and air, minimum survival occurred at 50 to 55% relative humidity (rh) for wet dissemination and at 75% rh for dry dissemination. this shift indicated that aerosols produce ... | 1971 | 4994903 |
| [subacute bacterial endocarditis as complication of infections carried from animal to human (zoonosis-endocarditis)]. | 1971 | 4995737 | |
| antigens of pasteurella tularensis: preparative procedures. | ether-water (ew) extraction of pasteurella tularensis produced better antigens than five other chemical procedures. ew extracts produced from stationary-phase, liquid-grown, saline suspensions of strain schu s4 cells regularly induced agglutinin and precipitin formation in rabbits. mice, guinea pigs, and monkeys also responded to ew extracts but with lower antibody levels. the use of strains of lower virulence, acetone-dried cells, organisms grown on a solid medium, and abbreviated extraction co ... | 1971 | 4999975 |
| microagglutination procedures for febrile agglutination tests. | febrile agglutination tests were done by using as antigens brucella abortus, salmonella group d, proteus ox19, and pasteurella tularensis. comparison of results from 23 sera showed that the microtechnique, rapid slide, and test tube methods gave similar titers, although those from the microtechnique were generally higher. the sensitivity of the microtechnique depended upon the concentration of antigen, and, to obtain reproducible results, the optimal concentration of antigens had to be determine ... | 1971 | 5002142 |
| the use of immunofluorescence in grouping of streptococci and in diagnosis of tularemia. | 1971 | 5290603 | |
| properties of aldolase from francisella tularensis. | the aldolase of francisella tularensis resembles class ii aldolases in its requirement for divalent ions and its inactivation by metal chelating agents. cysteine and other reducing agents stimulated the activity of the enzyme. | 1971 | 5547987 |
| [lytic action of sodium desoxycholate on the causative agent of tularemia]. | 1971 | 5560797 | |
| characterization of the endogenous mediator(s) of serum zinc and iron depression during infection and other stresses. | 1971 | 4399096 | |
| the definition and application of evaluation techniques as a guide for the improvement of fluorescent antibody reagents. | 1971 | 4400555 | |
| antitissue versus antimicrobial cellular immunity: a perspective. | 1971 | 4941265 | |
| effect of infection and endotoxicosis on plasma lactate dehydrogenase isozymes in white rats. | vertical slab electrophoresis in polyacrylamide gels was used to monitor changes in lactate dehydrogenase (ldh) isozymes in plasma of white rats during bacterial infection and endotoxin poisoning. peritoneal infection with francisella tularensis and salmonella typhimurium and administration of s. typhimurium endotoxin stimulated significant increases in plasma ldh-5. rates of change in enzyme activity after infection were directly related to size of infecting dose and type of agent employed. inf ... | 1971 | 4949502 |
| preparation of agglutinating antisera and fluorescent-antibody conjugates against pasteurella tularensis in equines. | the serological response in burros and horses to the viable lvs strain of pasteurella tularensis was studied. high-titered agglutinating antisera and fluorescent-antibody conjugates were obtained in both groups of animals. maximum titers were obtained in horses 14 to 21 days after the start of vaccination and in burros 21 to 28 days after the start of vaccination. the use of woodhour's adjuvants or booster inoculations did not result in increased titers. | 1970 | 4917187 |