Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| nonlinear effects of glutamate and kcl on glutamate toxicity in cultured rat cerebellar neurons. | nonlinear responses to toxin exposure have been observed in multiple cell types and organisms across a wide array of phyla. high dose toxin exposures inhibit or kill biological systems, while low dose exposures can stimulate survival mechanisms. we examined the effects of low (10(-3), 10(-5), 10(-7), and 10(-9) m) and ultra-low (10(-25) and 10(-61) m) kcl and glutamate pretreatment (72 h) against glutamate toxicity in rat cerebellar neurons. ultra-low dilutions (10(-31), 10(-61), and 10(-401)) o ... | 2003 | 12856478 |
| dermatitis from arnica montana. | 2003 | 145351 | |
| arnica montana and homeopathic dosing guidelines. | 2003 | 12900640 | |
| homeopathic treatment in emergency medicine: a case series. | following a multiple-casualty construction disaster in israel, members of the center of integrated complementary medicine joined in the emergency activity of the shaare zedek medical center. they administered homeopathic treatment to injured patients to supplement conventional orthopaedic treatment. this was to our knowledge the first time that complementary medicine had been used officially in conjunction with conventional medicine in an emergency situation. our objective is to report and summa ... | 2003 | 12587994 |
| contact sensitization from compositae-containing herbal remedies and cosmetics. | the compositae (asteraceae) family of plants is currently an important cause of allergic plant contact dermatitis in europe. the family comprises some of the oldest and most valued medicinal plants, and the increasing popularity of herbal medicine and cosmetics may theoretically result in a growing number of compositae sensitizations from these sources. according to the literature at least 15 species, including among others arnica (arnica montana), german and roman chamomile (chamomilla recutita ... | 2002 | 12492516 |
| mycorrhizal plants of traditionally managed boreal grasslands in norway. | this paper reports on the mycorrhizal status of 82 plant species growing in traditionally managed grasslands in three different locations in the boreal and boreo-nemoral vegetation zone in the eastern part of norway. seventy-four species were found to have arbuscular mycorrhiza (am). to our knowledge, we report am for the first time in achillea ptarmica, ajuga pyramidalis, alchemilla glaucescens, carex brunnescens, carex pallescens, crepis praemorsa, hieracium lactucella, rumex longifolius, scor ... | 2002 | 12072981 |
| studies on the anti-inflammatory activity of phytopharmaceuticals prepared from arnica flowers. | phytopharmaceuticals prepared from flowerheads of arnica montana of spanish origin and of the new type "arbo", which can be easily and economically cultivated, were studied for their capability to impair activation of the transcription factors nf-kappa b and nf-at. both proteins are responsible for the transcription of genes encoding various inflammatory mediators. additionally, their influence on the release of the cytokines il-1 and tnf-alpha were examined. the inhibitory activities correlate ... | 2002 | 12058311 |
| final report on the safety assessment of arnica montana extract and arnica montana. | arnica montana extract is an extract of dried flowerheads of the plant, arnica montana. arnica montana is a generic term used to describe a plant material derived from the dried flowers, roots, or rhizomes of a. montana. common names for a. montana include leopard's bane, mountain tobacco, mountain snuff, and wolf's bane. two techniques for preparing arnica montana extract are hydroalcoholic maceration and gentle disintegration in soybean oil. propylene glycol and butylene glycol extractions wer ... | 2001 | 11558636 |
| the seamy side of natural medicines: contact sensitization to arnica (arnica montana l.) and marigold (calendula officinalis l.). | medical remedies of plant origin have gained increasing popularity in recent years. both anaphylactic and eczematous allergic reactions are on the rise, accordingly. arnica and marigold, both of the compositae family, are in widespread use, but only limited data are available on their allergenic potential. we tested 443 consecutive patients, in addition to the european standard and other series, with compositae mix, sesquiterpene lactone mix, arnica, marigold, and propolis. 5 subjects ( approxim ... | 2001 | 11722485 |
| potential for danger with arnica montana. | 2001 | 11293536 | |
| in vitro antimicrobial activity of propolis and arnica montana against oral pathogens. | arnica and propolis have been used for thousands of years in folk medicine for several purposes. they possess several biological activities such as anti-inflammatory, antifungal, antiviral and tissue regenerative, among others. although the antibacterial activity of propolis has already been demonstrated, very few studies have been done on bacteria of clinical relevance in dentistry. also, the antimicrobial activity of arnica has not been extensively investigated. therefore the aim here was to e ... | 2000 | 10716618 |
| effect of traumeel s, a homeopathic formulation, on blood-induced inflammation in rats. | to evaluate the activity of traumeel s (trs), a homeopathic formulation containing arnica montana and other plant extracts and minerals on an animal model of traumatic inflammation. | 1999 | 10709306 |
| contact dermatitis caused by sesquiterpene lactones. | compositae dermatitis involves workers such as gardeners, florists, and farmers, and less commonly people not employed in occupations at risk. | 1998 | 9471988 |
| [effect of arnica montana on the state of lipid peroxidation and protective glutathione system of rat liver in experimental toxic hepatitis]. | effects of tinctura arnica on lipids peroxidation and on the protective glutathions system of liver in rats in case of experimental toxic hepatitis have been studied. toxic hepatitis is accompanied by deep alterations of the oxidant-antioxidant status of the body. intoxication of the body by ccl4 results in intensification of the free radicals formation particularly in liver: accumulation of lipids peroxidation molecular products, glutathione system enzyme activity inhibition in early terms and ... | 1998 | 9848164 |
| [effect of arnica montana tincture on some hydrolytic enzyme activities of rat liver in experimental toxic hepatitis]. | effects of tinctura arnica on arginase, adenosine triphosphatase, glucose-6-phosphatase and 5'-nucleotidase activities of rats liver in case of experimental toxic hepatitis have been studied. toxic hepatitis was caused by 2 times interstomach administration of 0.25 ml oil solution of carbon tetrachloride per 100 g of animal weight. 20 mkl/100 g of tinctura arnica was administered every day per os for 14 days. the enzyme activities have been investigated at 3, 7 and 17 days. a significant dementi ... | 1998 | 10402655 |
| efficacy of homeopathic arnica: a systematic review of placebo-controlled clinical trials. | the efficacy of homeopathic remedies has remained controversial. the homeopathic remedy most frequently studied in placebo-controlled clinical trials is arnica montana. | 1998 | 9820349 |
| sesquiterpene lactone content in leaves of in vitro and field cultivated arnica montana. | on the basis of gc and gc/ms analyses we report on the full qualitative and quantitative sesquiterpene lactone (stl) content of in vitro cultivated a. montana plantlets consisting of helenalin and 11alpha,13-dihydrohelenalin esters in approximately equal amounts. the accumulation of stl was shown to be correlated with tissue differentiation in the above-ground parts. the seasonal variation of stl content in leaves of a. montana cultivated in the proving field was investigated. changes in the com ... | 1998 | 17253241 |
| helenalin, an anti-inflammatory sesquiterpene lactone from arnica, selectively inhibits transcription factor nf-kappab. | alcoholic extracts prepared form arnicae flos, the collective name for flowerheads from arnica montana and a. chamissonis ssp. foliosa, are used therapeutically as anti-inflammatory remedies. the active ingredients mediating the pharmacological effect are mainly sesquiterpene lactones, such as helenalin, 11alpha,13-dihydrohelenalin, chamissonolid and their ester derivatives. while these compounds affect various cellular processes, current data do not fully explain how sesquiterpene lactones exer ... | 1997 | 9348104 |
| mekc as an improved method to detect falsifications in the flowers of arnica montana and a. chamissonis. | arnica montana and arnica chamissonis ssp. foliosa flowers are often adultered by blending them with those from heterotheca inuloides. tlc, hplc, and tsp lc/ms have been proposed to detect this kind of falsification. a new method based on micellar electrokinetic chromatography (mekc) has been developed. this procedure permits us to characterize rapidly each drug and to detect easily falsifications from h. inuloides in arnica drugs. | 1994 | 17236057 |
| [the effects of arnica montana on blood coagulation. randomized controlled trial]. | the purpose of this study, which took the form of a two-period cross-over clinical trial, was to determine whether a homeopathic substance, arnica montana, significantly decreased bleeding time (simplate ii) and to describe its impact on various blood coagulation tests. it was not shown that this substance had a significant impact on various parameters of blood coagulation in healthy volunteers in the period immediately following administration [corrected]. | 1993 | 7903572 |
| helenalin acetate in in vitro propagated plants of arnica montana. | propagated "in vitro" shoots and plantlets of arnica montana l. (asteraceae) have been shown to produce sesquiterpene lactones, i.e. helenalin and 11,13-dihydrohelenalin esters. the compounds were detected in green organs only; roots of the plantlets contained no sesquiterpene lactones. the helenalin acetate content in leaves of the plantlets (0.073% dry wt) was 4-times higher than in proliferated shoots (0.016% dry wt). the best rate of shoot multiplication was achieved on ms medium, supplement ... | 1993 | 17230337 |
| tussilagine and isotussilagine: two pyrrolizidine alkaloids in the genus arnica1. | in flowerheads of arnica montana, a. chamissonis ssp. foliosa, a. amplexicaulis, and a. sachalinensis, traces of the non-toxic pyrrolizidine alkaloids tussilagine and isotussilagine were detected. their identity was unambiguously confirmed by direct comparison (tlc, gc, gc/ms) with the authentic samples. | 1992 | 17226521 |
| new flavonoid glycosides from arnicae flos dab 91. | five flavonoid glycosides were identified from flowers of arnica montana, ten from a. chamissonis subsp. foliosa var. incana. the structures were established on the basis of acid hydrolysis and spectral data (uv, nmr, ms) as the 7-beta-glucosides of pectolinarigenin, apigenin, and chrysoeriol; luteolin 3'- o-beta-glucoside; the 3-beta-glucuronides of kaempferol, isorhamnetin, and 6-methoxykaempferol; the 3,7-di-beta-glucosides of quercetin and patuletin; the 3-beta-glucosides of betuletol and qu ... | 1992 | 17226484 |
| shoot tip culture of arnica montana for micropropagation. | multiple shoots were regenerated from shoot tips of arnica montana on ms and b5 media supplemented with ba (1 mg/l) and naa (0.1 mg/l). sections of 1-2 mm in length cultured from in vitro germinated seedlings regenerated 7.7 (mean) shoots on the ms medium, whereas sections cultured from greenhouse plants regenerated 9.0 (mean) shoots on the b5 medium within 6 weeks. subsequent subcultures of shoots on the same media but without naa resulted in similar or lower multiplication rates (1.6 to 3.1 in ... | 1992 | 17226438 |
| [effect of arnica d 30 during hard physical exertion. a double-blind randomized trial during the oslo marathon 1990]. | the effect of arnica montana on stiffness, restitution time and cell damage during hard physical exercise was evaluated in a randomized double blind trial during the oslo marathon. 36 participants were randomized: one group received arnica 10(-30) five pills twice daily for five days, starting the day before the event. the other group received placebo pills. blood tests were carried out before and immediately after finish, and after 48 and 72 hours. stiffness was evaluated on a visual analogue s ... | 1991 | 1780819 |
| immunologically active polysaccharides of arnica montana cell cultures. | from the nutrition medium of arnica montana cell cultures two homogeneous polysaccharides, an acidic arabino-3,6-galactan-protein with mean mr of 100,000 and a neutral fucogalactoxyloglucan with mean mr of 22,500 have been isolated by deae-sepharose cl-6b and sephacryl s-400 column chromatography. their structures were elucidated mainly by methylation analysis, partial acidic and enzymatic hydrolysis and 13c nmr spectroscopy. the fucogalactoxyloglucan shows a pronounced enhancement of phagocytos ... | 1991 | 1367382 |
| [immunologic studies of plant combination preparations. in-vitro and in-vivo studies on the stimulation of phagocytosis]. | the activity of phagocytosis was tested in the in vitro granulocyte test and the in vivo carbon-clearance-test in the mouse for an extract combination consisting of four plant extracts (echinacea angustifolia, eupatorium perfoliatum, baptisia tinctoria and arnica montana). in both immune models, a step by step stimulation of the activity of phagocytosis by the addition of the four plant extracts was shown with an increase in effectiveness of partially over 50% in comparison to the pure echinacea ... | 1991 | 1799388 |
| helenalin and 11 alpha,13-dihydrohelenalin, two constituents from arnica montana l., inhibit human platelet function via thiol-dependent pathways. | this study investigates the effect on human platelet function of two sesquiterpene lactones from arnica montana l., helenalin (h) and 11 alpha,13-dihydrohelenalin (dh). both compounds inhibited collagen-induced platelet aggregation, thromboxane formation and 5-hydroxytryptamine secretion in a concentration-dependent manner at 3-300 microm. when arachidonic acid was used as stimulus, thromboxane formation remained unaffected despite of inhibition of platelet aggregation. both h and dh reduced the ... | 1990 | 2116680 |
| postpartum homeopathic arnica montana: a potency-finding pilot study. | 1990 | 2102159 | |
| flavonoid glucuronides from the flowers of arnica montana1. | five flavonoid glucuronides were identified from flowers of arnica montana l. the structures were established on the basis of total acid hydrolysis and spectral data (uv, (1)h-nmr, (13)c-nmr, mass) as 3- o-beta- d-glucuronides of quercetin, kaempferol, isorhamnetin, patuletin, and 6-methoxykaempferol. the last one is a new natural compound. this is the first report on glucuronides in the genus arnica. additionally, tricin and 3,5,7-trihydroxy-6,3',4'-trimethoxyflavone were identified. up to now ... | 1988 | 17265264 |
| characterization of arnica montana l. flowers. | 1987 | 3455222 | |
| flavonoid glycosides from arnica montana and arnica chamissonis. | five flavonoid glycosides were identified from flowers of arnica montana, four from a. chamissonis subsp. foliosa var. incana. the structures were established on the basis of total acid hydrolysis and spectral data (uv, (1)h-nmr, (13)c-nmr, ms) as hispidulin 7- o-beta-glucoside, isorhamnetin 3- o-beta-glucoside, 3- o-beta- d-glucopyranosides of spinacetin, 6-methoxykaempferol and patuletin and querectin 3- o-(6''- o-acetyl)-beta- d-glucopyranoside. the latter compound can serve as distinctive ma ... | 1987 | 17269063 |
| [immunostimulating action of polysaccharides (heteroglycans) from higher plants]. | from the water or alcaline-water extracts of echinacea purpurea (l.) moench. and -angustifolia dc., eupatorium cannabium l. and -perfoliatum l., chamomilla recutita l. rauscher, calendula officinalis l., baptisia tinctoria (l.) r. b., achyrocline satureioides dc., arnica montana l., sabal serrulata roem. et schult., and eleutherococcus (acanthopanax) senticosus maxim. polysaccharide fractions with molecular weights in the range of 25 000 to 500 000 and higher have been isolated, which, according ... | 1985 | 4052142 |
| methylated flavonoids from arnica montana and arnica chamissonis. | from the flowers of arnica chamissonis less, subsp. foliosa var. incana, the methylated flavonoids acacetin, pectolinarigenin, hispidulin, jaceosidin, 6-methoxykaempferol, and betuletol have been isolated and identified by spectroscopic methods. except for acacetin, the same flavonoids were identified in the flowers of arnica montana l. betuletol was found for the first time in the family of asteraceae. | 1984 | 17340267 |
| 6-o-isobutyryl-tetrahydrohelenalin from the flowers of arnica montana. | from the flowers of arnica montana l., the helenanolides 6- o-isobutyryl-tetrahydrohelenalin and 2beta-ethoxy-6- o-isobutyryl-2,3-dihydrohelenalin were isolated and their structures established by spectroscopic methods. | 1984 | 17340245 |
| metronidazole (flagyl) and arnica montana in the prevention of post-surgical complications, a comparative placebo controlled clinical trial. | a double blind trial, was designed, in which 118 patients undergoing the removal of impacted wisdom teeth were randomly divided into the following groups; 41 patients received metronidazole, 39 patients received arnica montana, 38 patients received the placebo. metronidazole was more effective in pain control than arnica (p less than 0.001) and placebo (p less than 0.01). it prevented swelling better than arnica (p less than 0.01) and placebo (p less than 0.05) and was more effective in promotin ... | 1984 | 6365158 |
| [immunostimulant action of polysaccharides (heteroglycans) from higher plants. preliminary communication]. | from the water or alcaline-water extracts of echinacea purpurea (l.) moench and -angustifolia dc., eupatorium cannabinum l. and -perfoliatum l., chamomilla recutita (l.) (rauscher), calendula officinalis l., baptisia tinctoria (l.) r.b., achyrocline satureoides dc., arnica montana l., sabal serrulata roem et schult. and eleutherococcus senticosus maxim. polysaccharide fractions with molecular weights in the range of 25 000 to 500 000 and higher have been isolated, which, according to the granulo ... | 1984 | 6541484 |
| [helenalin- and 11,13-dihydrohelenalinester from flowers of arnica montana.]. | from the flowers of arnica montana l. 13 helenanolides were isolated and identified. they are shown to be 11,13-dihydrohelenalin ( 1), helenalin ( 2) and their ester derivatives 3-13 (see figure). the natural occurence of 6-o-isobutyryl-, 6-o-tigloyl-, 6-o-isovaleryl- and 6-o-(2-methyl)-butyrylhelenalin (compounds 9, 11, 12, 13) is reported for the first time. the qualitative sesquiterpene lactone composition in flowers of a. montana from different regions was found to be variable. | 1983 | 17405058 |
| [efficacy of the phenol compounds of arnica in toxic lesion of the liver]. | experiments on rats with toxic liver injury induced by carbon tetrachloride have shown that the preparation presenting a sum of phenolic compounds of arnica montana and foliated arnica favours a more complete recovery of the bile secretion intensity, synthesis and excretion with bile of bile acids and bilirubin, and cholesterol excretion. it also accelerates the recovery of activity of serum enzymes. | 1983 | 6852212 |
| [arnica allergy]. | arnica montana l. (plant family: compositae) is one of the oldest and most important drug plants. besides its healing effects it also reveals sensitizing properties. from the literature more than 35 references with more than 100 cases of contact dermatitis could be cited, completed by four own cases. in most cases sensitization was induced by self treatment with tincture of arnica, whereas occupational contact dermatitis in drug sellers of pharmacists is rare. chemical and animal experimental in ... | 1980 | 6993423 |
| the sensitizing capacity of compositae plants. i. occupational contact dermatitis from arnica longifolia eaton. | three patients with occupational contact dermatitis due to arnica longifolia eaton and arnica montana l. are reported. during cultivation, harvesting of the flower heads, chemical investigation of the sesquiterpene lactone constituents and preparation of therapeutic tinctures, they had frequent contact with the plant materials. patch tests with the two sesquiterpene lactones carabron and helenalin, isolated during investigation from a. longifolia eaton, were positive in all three patients, thoug ... | 1978 | 148995 |
| identification of the allergens of arnica montana l. | 1978 | 154377 | |
| helenalinmethacrylate, a new pseudoguaianolide from the flowers of arnica montana l. and the sensitizing capacity of their sesquiterpene lactones. | 1978 | 704699 | |
| [new components of blossoms from arnica montana l]. | 1974 | 4134079 | |
| [identification of carotenoids in arnica montana]. | 1973 | 4732114 | |
| [fatty acids of the essential oil from leaves of arnica montana and arnica longifolia]. | 1972 | 4403598 | |
| [a still mysterious medicinal plant, arnica montana l]. | 1971 | 4927860 | |
| [arnica montana l]. | 1968 | 5681721 | |
| [cultivation experiments with arnica species. ii. vegetative propagation of arnica montana l]. | 1967 | 5603484 | |
| [contribution to the knowledge of the substances contained in arnica montana l]. | 1966 | 5926222 | |
| [therapeutic experiences with arnica montana]. | 1965 | 14263823 | |
| [some new constituents from the roots of arnica montana]. | 1963 | 13987185 | |
| [arnica montana as a medicinal plant]. | 1959 | 13834712 | |
| [arnica montana as a medicinal plant]. | 1959 | 13676103 | |
| [study on the constituents of arnica montana l]. | 1956 | 13328059 | |
| [arnica montana mistaken for inula britannica]. | 1954 | 13177151 | |
| [possible testing of tinctures of arnica montana l..]. | 1954 | 13198192 | |
| [arnica montana. iii]. | 1953 | 13073437 | |
| [arnica; arnica montana. ii]. | 1953 | 13073424 | |
| [arnica (arnica montana)]. | 1953 | 13073403 | |
| [arnica montana]. | 1952 | 12983199 | |
| [pharmacology of arnica montana l]. | 1949 | 15406032 |