Publications

anti-inflammatory effect of the aqueous extract from lonicera japonica flower is related to inhibition of nf-kappab activation through reducing i-kappabalpha degradation in rat liver.	we investigated the anti-inflammatory effects of aqueous extract from lonicera japonica flower (aelj), a traditional skin rash drug, in lipopolysaccharide (lps)-induced rat liver sepsis. immunoblot analysis showed that the level of nuclear factor (nf)-kappabp65 was rapidly up-regulated and inhibitory (i)-kappabalpha was down-regulated by lps challenge. however, aelj inhibited the increase of nf-kappabp65 and degradation of i-kappabalpha in the liver of lps-challenged rats. immunohistochemical an ...	2001	11115613
differential inhibition of reverse transcriptase and cellular dna polymerase-alpha activities by lignans isolated from chinese herbs, phyllanthus myrtifolius moon, and tannins from lonicera japonica thunb and castanopsis hystrix.	two lignans, phyllamycin b and retrojusticidin b isolated from phyllanthus myrtifolius moon have been demonstrated to have a strong inhibitory effect on human immunodeficiency virus-1 reverse transcriptase activity (hiv-1 rt), but much less inhibitory effect on human dna polymerase-alpha (hdnap-alpha) activity. fifty percent inhibitory concentrations of phyllamycin b and retrojusticidin b were determined to be 3.5 and 5.5 microm for hiv-1 rt, and 289 and 989 microm for hdnap-alpha, respectively. ...	1995	8540756
inactivation of phospholipase a2 by naturally occurring biflavonoid, ochnaflavone.	ochnaflavone, a medicinal herb product isolated from lonicera japonica, strongly inhibited rat platelet phospholipase a2 (ic50, about 3 microm). inactivation was concentration and ph dependent (maximum inactivation occurred between ph 9.0 and 10.0). ochnaflavone inhibited the enzyme by a noncompetitive manner, with the apparent ki value of 3 x 10(-5) m. reversibility was studied directly by dialysis method; the inhibition was irreversible. in addition, the inhibitory activity of ochnaflavone is ...	1994	7999121
the quest for a herbal contraceptive.	an oral herbal contraceptive would allow couples control their fertility without consulting a health worker, which in turn would likely markedly increase the number of couples practicing family planning. other advantages of such a contraceptive would include the familiarity rural people have with herbal medicines, the fewer side effects associated with herbal preparations, their ready availability from local sources, and protection of privacy. there are many references to plants in india with ...	1993	8241931
[clinical and experimental study of xiao er ke cuan ling oral liquid in the treatment of infantile bronchopneumonia].	xiao er ke chuan ling oral liquid (kcl) is a chinese herbal preparation consisted of 10 herbs such as prunus armeniacae, scutelaria baicalensis, lonicera japonica etc. 30 children suffering from bronchopneumonia and/or acute bronchitis were treated with kcl (treated group) and another 30 cases were treated with penicillin and aminophylline (control group). results: cure rate and effective rate in treated group was 26.6%, and 93.3% respectively. while in control group was 30% and 96.6% respective ...	1992	1304839
inhibition of platelet activation and endothelial cell injury by polyphenolic compounds isolated from lonicera japonica thunb.	effects of the polyphenolic compounds isolated from lonicera japonica thunb on platelet aggregation, platelet thromboxane biosynthesis and hydrogen peroxide-induced endothelial cell injury were studied. with regard to the inhibitory effect on human platelet aggregation, methyl caffeate, 3,4-di-o-caffeoylquinic acid and methyl 3,4-di-o-caffeoylquinate had a strong effect. they significantly inhibited the second wave of platelet aggregation induced by adp. concerning thromboxane biosynthesis trigg ...	1992	1603820
[clinical and experimental study of the effect of kang er xin-i on viral myocarditis].	kang er xin-i (kex-i) is a proved recipe used to treat viral myocarditis. it consists of lonicera japonica, ophiopogon japonicus, astragalus membranaceus mainly and possesses the effect of clearing away heat and toxic materials and supplementing the vital energy and nourishing. the clinical study was carried out with kex-i according to a random, paired and cross-over design. coenzyme q10 was used as a control and left ventricular function was observed. the result showed: after being treated with ...	1991	1659497
[the combined modulating effects of cerium nitrate with certain chinese traditional drugs on altered cell-mediated immunities in scald mice].	altered cell-mediated immunities (cmi) is one of the important causes of increased susceptibility to infection and, high mortality of burned patients. this paper presents the experimental work on mice with scald injury to restore their altered cmi by local application of cerium nitrate (ce) or systemic administration of astragalus membranaceus (am) or lonicera japonica thunb (ljt), as well as combination use of these drugs. the proliferative response to con a and the ability of il-2 production o ...	1990	2086133
studies on the saponins of lonicera japonica thunb.		1988	3246039