Publications

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skin testing with extracts of fungal species derived from the homes of allergy clinic patients in toronto, canada.airborne fungi in the homes of patients with allergic rhinitis or asthma, from a toronto allergy clinic population, were isolated, quantified and identified to species. allergen extracts were prepared from sixteen of these isolated species and used for skin-prick testing of twenty-six patients. fourteen of the total patients reacted to one or more of these extracts at 1:10 (w/v) concentrations. the most common positive skin responses (8/14 to 6/14) were found for cladosporium cladosporioides, al ...19883349592
production of mannitol by fungi from cotton dust.cotton dust associated with high pulmonary function decrements contains relatively high levels of mannitol. in this study, cotton leaf and bract tissue and dust isolated from cotton leaf tissue were examined by optical microscopy, scanning electron microscopy, and capillary gas chromatography. alternaria alternata, cladosporium herbarum, epicoccum purpurascens, and fusarium pallidoroseum were isolated from cotton leaf dust. the fungal samples, cotton dust, and cotton leaf contained mannitol. thi ...198816347688
black fungi: a survey of dematiaceous hyphomycetes from clinical specimens identified over a five year period in a reference laboratory.five hundred and fifty six dematiaceous hyphomycetes, the great majority referred from other laboratories, were identified by us over a five year period. of these, thirty five were regarded as being of probable pathogenetic significance. these included seven isolates associated with chromoblastomycosis, and seven isolates thought to be causing phaeohyphomycosis. there were six strains of phaeoannellomyces werneckii and five strains of sporothrix schenckii. seven isolates, all strains of aureobas ...19873431915
aeroallergens of the southeast missouri area: a report of skin test frequencies and air sampling data.aeroallergens in the southeast missouri area were identified by analyzing the positive skin tests of eight hundred seventeen patients and five years of air sampling. the important trees, grasses and weeds are enumerated. reactivity levels of house dust, feathers and dermatophagoides farinae exceeded all others. first among the fungi was epicoccum purpurascens .19846731948
production and isolation of siderophores from the soil fungus epicoccum purpurascens.a large number of iron transport agents, siderophores, which stimulated the growth of arthrobacter flavescens jg-9, were isolated during a study of the antitumor activity associated with the metabolic products of the fungus epicoccum purpurascens. the production of the siderophores was significantly enhanced in a variety of media by culture of the fungus in the near absence of ferric iron. a novel method of purification involving a carboxylic ion-exchange resin separated the siderophores into fo ...19816453608
structure of triornicin, a new siderophore.spectroscopic analysis of the tumor inhibitory factor triornicin produced by epicoccum purpurascens indicated that it was of similar structure to the known siderophore desferricoprogen, which is also produced by the fungus. the 1h and 13c nmr spectra indicated the replacement of an (e)-5-hydroxy-3-methyl-2-pentenoyl moiety of the desferricoprogen structure with an acetyl function. cleavage of triornicin with basic methanol produced two fragments. the first was identified as a natural siderophore ...19817195281
new antibiotics from the fungus epicoccum nigrum. i. fermentation, isolation and antibacterial properties.an atmosphere isolate of the fungus epicoccum nigrum was found to exhibit an activity against staphylococcus aureus. a more active, non-sporulating variant of this strain was selected. from its fermentation broth, two novel compounds, epicorazines a and b, were isolated by preparative tlc and tested against a series of bacteria.1978721706
new antibiotics from the fungus epicoccum nigrum. iii. epicorazine b: structure elucidation and absolute configuration.comparison of uv, ir, pmr and cd spectra of epicorazine b with those of epicorazine a, a previously isolated metabolite of epicoccum nigrum, showed that they were isomers with the same epidithiodiketopiperazine skeleton. x-ray determination of epicorazine b indicated that the difference is related to a cis-trans configuration.1978569142
new antibiotics from the fungus epicoccum nigrum. ii. epicorazine a: structure elucidation and absolute configuration.an antibiotic, epicorazine a, isolated from a particular strain of the fungus epicoccum nigrum, was shown to be a new epidithiodiketopiperazine from its uv, ir, mass, nmr and cd spectra. x-ray diffraction measures confirmed this structure and its absolute configuration.1978569141
molds on vegetables at the time of harvest.the mean numbers of colony-forming units of molds present on vegetables at the time of harvest were in the range of 4.2 x 10(3) to 6.7 x 10(3)/g for all vegetables except cucurbits and asparagus. the numbers were not influenced by cultivars within species, duration of the growing season, distant separation of the growing fields, or elevation above ground. numbers increased with rainfall during either of 3 days before harvest and decreased when the mean daily temperature exceeded 24 degrees c. th ...1978646353
a study on fungal radioresistance and sensitivity.lower doses of gamma and x-rays (5 and 1 krad, respectively) stimulated the spore germination and growth of 7 tested fungi. higher doses (500 and 100 krad, respectively) revealed that epicoccum nigrum was the most radioresistant, while alternaria humicola, stemphylium verruculosum, rhizopus nigricans, and cladosporium herbarum were of moderate resistance. aspergillus niger and penicillium oxalicum were the most radiosensitive. protein and polysaccharide synthesis were inhibited in the mycelium d ...1977857505
isolation and biological activity of the pigments of the mold epicoccum nigrum. 1976818140
possible role of solar radiation on the viability of some air fungi in egypt.the high occurrence of alternaria humicola and the moderate occurrence of stemphylium verruculosum, rhizopus nigricans, and epicoccum nigrum in the air of egypt could be correlated to their apparent resistance to solar radiation. cladosporium herbarum, aspergillus niger, and penicillium oxalicum, although highly occurring, were light-sensitive. the miniumum solar radiation in november, coupled with the highest total fungal catch, dominated by cladosporium herbarum, reveals the importance of sola ...19761037050
carotenoids in some ultraviolet mutants of epicoccum nigrum link. 19704321157
a note on properties of pigments produced by epicoccum nigrum. 19705465560
fungistatic action of the pigment secreted by the fungus epicoccum nigrum link. 19705530290
carotenogenesis in diphenylamine-treated epicoccum nigrum link. 19695813303
on some pigments of epicoccum nigrum link: their isolation and structure elucidation and a biosynthetic pathway of rhodoxanthin. 19694920722
growth and pigmentation of epicoccum nigrum in submerged culture.growth and pigmentation of epicoccum nigrum was studied in submerged culture in various media. red pigmentation of the mycelium and of fermentation broth was obtained only in a medium containing glucose and yeast autolysate. this pigmentation occurred at the time of maximal production of carotenoids. observations on the submerged culture of this organism in flasks and in fermentors are described, and the details of a standardized procedure for the production of carotenoid pigments are given.196916349848
lipids produced by epicoccum nigrum in submerged culture.1. the lipids of the red mycelium of the fungus epicoccum nigrum link were investigated. four carotenoid pigments were isolated and identified as beta-carotene, gamma-carotene, rhodoxanthin and torularhodin. 2. for the first time rhodoxanthin was isolated as a fungal metabolite. 3. linoleic acid was the major fatty acid in the total lipids. 4. ergosterol was present in the lipids in the non-esterified form.19685753092
carotenoid incorporation into rhodoxanthin by epicoccum nigrum link. 19685734036
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