Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| synthesis and antileishmanial and antimicrobial activities of some 2,3-disubstituted 3h-quinazolin-4-ones. | a series of 2,3-disubstituted 3h-quinazolin-4-ones was synthesized. antimicrobial activities of the synthesized compounds were investigated against gram (+ve) and gram (-ve) bacteria, including b. subtilis, s. aureus, s. flexneri, p. aeruginosa, and s. typhi, and six fungi, namely trichophyton longifusus, candida albicans, aspergillus flavus, microsporum canis, fusarium solani, and candida glabrata using the broth microdilution method. compounds 9, 11, and 12 showed significant activities agains ... | 2010 | 20235747 |
| [tinea capitis: two years experience in a paediatric hospital of buenos aires, argentina]. | tinea capitis is an infection caused by dermatophytes of the genera microsporum and trichophyton, and constitutes a major health problem in argentina. the aim of the present study was to find out the incidence of those etiological agents and the therapeutic response in patients attending a high-complexity paediatric hospital within a two-year period. a total of 98 tinea capitis were diagnosed, 13 of which were celsus kerion. microsporum canis was isolated in 61.28%. the range of values for minim ... | 2010 | 20346290 |
| disease progression of dermatophytic pseudomycetoma in a persian cat. | dermatophytic pseudomycetoma is a subcutaneous fungal infection by microsporum canis. | 2010 | 20346294 |
| a zoonotic ringworm outbreak caused by a dysgonic strain of microsporum canis from stray cats. | cats are frequent carriers of microsporum canis and veterinary students are at high risk of exposure and acquisition of the organism a la infección. | 2010 | 20346301 |
| historical aspects of dermatomycoses. | physicians have been aware of superficial fungal infections for centuries, but the causal agents and treatments of fungal infections remained unknown until the mid-1800s, when numerous important findings were reported. among the relevant researchers in the field of superficial mycoses were remak, who found the fungal nature of favus in 1837; berg, who reported oral candidosis in 1841; and wilkinson, who described vaginal candidosis in 1849. tinea versicolor was described clinically in 1846 by ei ... | 2010 | 20347652 |
| inflammatory tinea capitis: kerion, dermatophytic granuloma, and mycetoma. | inflammatory tinea capitis is the result of a hypersensitivity reaction to a dermatophytic infection. the usual forms are favus, kerion celsi, dermatophytic majocchi granuloma, and mycetoma. inflammatory tinea capitis can be caused by microsporum canis, trichophyton mentagrophytes, t tonsurans, t rubrum, and m gypseum. histopathologic findings include a spectrum from mild suppurative folliculitis to dense granulomatous infiltrates. in mycetoma, grains must be present. | 2010 | 20347653 |
| the changing face of microsporum spp infections. | significant changes in epidemiology, etiology, and the clinical pattern of mycotic infections caused by microsporum spp have been observed in recent years. fungal infections caused by m canis, followed by m gypseum and m hominis, involving skin and its appendages, represent one of the most common diseases worldwide and a recalcitrant problem in dermatology that demands appropriate diagnostic and treatment strategies. the most striking clinical phenomena of superficial and kerion and other forms ... | 2010 | 20347656 |
| identification of antibacterial and antifungal pharmacophore sites for potent bacteria and fungi inhibition: indolenyl sulfonamide derivatives. | synthesis of seven new indolenyl sulfonamides, have been prepared by the condensation reaction of indole-3-carboxaldehyde with different sulfonamides such as, sulphanilamide, sulfaguanidine, sulfathiazole, sulfamethoxazole, sulfisoxazole, sulfadiazine and sulfamethazine. these synthesized compounds have been used as potential ligands for complexation with some selective divalent transition metal ions (cobalt, copper, nickel & zinc). structure of the synthesized ligands has been deduced from thei ... | 2010 | 20005022 |
| composition and biological activity of the essential oil from leaves of plinia cerrocampanensis, a new source of alpha-bisabolol. | the essential oil from fresh leaves of plinia cerrocampanensis barrie (myrtaceae), obtained by hydrodistillation, was analysed by gc-fid and gc-ms. forty components, representing more than 91% of the oil, were identified. oxygenated sesquiterpenes represented the main fraction with alpha-bisabolol (42.8%) as the major constituent, making this plant a new and good source of this substance. biological activity of the essential oil was evaluated against several bacterial and fungal strains as well ... | 2010 | 20015638 |
| synthesis, structure, and antifungal evaluation of some novel 1,2,4-triazolylmercaptoacetylthiosemicarbazide and 1,2,4-triazolylmercaptomethyl-1,3,4-thiadiazole analogs. | novel 1-[[4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-yl]mercaptoacetyl]-4-alkyl/aryl-3-thiosemicarbazides (5-12) were synthesized by the reaction of 4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-ylmercaptoacetylhydrazide (4) with substituted isothiocyanates. cyclodehydration of thiosemicarbazides with concentrated sulfuric acid yielded 2-[4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-yl]mercaptomethyl-5-alkyl/arylamino-1,3, 4-thiadiazoles (13-17). the new compounds were evaluated ... | 2010 | 20030516 |
| in vitro antimicrobial activity of four ficus carica latex fractions against resistant human pathogens (antimicrobial activity of ficus carica latex). | methanolic, hexanoïc, chloroformic and ethyl acetate extracts of ficus carica latex were investigated for their in vitro antimicrobial proprieties against five bacteria species and seven strains of fungi. the green fruit latex was collected from chott mariam souse, middle east coast of tunisia. the antimicrobial activity of the extracts was evaluated and based respectively on the inhibition zone using the disc-diffusion assay, minimal inhibition concentration (mic) for bacterial testing and the ... | 2010 | 20067867 |
| circumscribed inflammatory plaque at the scalp: follicular impetigo or tinea capitis? | 2010 | 20084590 | |
| tinea capitis in southeastern china: a 16-year survey. | this survey was a retrospective of a 16-year (1993-2008) study on the incidence, clinical features, and etiological agents of tinea capitis mainly representing the southeastern china. the diagnosis was confirmed by direct microscopic examination. eight hundred and sixty-six patients with tinea capitis, 381 males (44%) and 485 females (56%), were enrolled in this study. patients were between 20 days and 84 years old with an average of 10.5 years and the peak incidence was in the age group of 6-10 ... | 2010 | 19936963 |
| argentinean propolis from zuccagnia punctata cav. (caesalpinieae) exudates: phytochemical characterization and antifungal activity. | this paper reports the in vitro antifungal activity of propolis extracts from the province of tucuman (argentina) as well as the identification of their main antifungal compounds and botanical origin. the antifungal activity was determined by the microdilution technique, using reference microorganisms and clinical isolates. all dermatophytes and yeasts tested were strongly inhibited by different propolis extracts (mics between 16 and 125 microg ml(-1)). the most susceptible species were microspo ... | 2010 | 19916546 |
| the spectrum of fungal infections with a special reference to dermatophytoses in the capital area of kuwait during 2000-2005: a retrospective analysis. | fungal infections constitute a major health problem all over the world. signs and symptoms induced by various dermatophytic infections are difficult to distinguish clinically from each other. so, characterization by in vitro culture is required for appropriate diagnosis and treatment as well as to study the epidemiological characteristics in a region. | 2010 | 19921463 |
| organization and evolutionary trajectory of the mating type (mat) locus in dermatophyte and dimorphic fungal pathogens. | sexual reproduction in fungi is governed by a specialized genomic region, the mating type (mat) locus, whose gene identity, organization, and complexity are diverse. we identified the mat locus of five dermatophyte fungal pathogens (microsporum gypseum, microsporum canis, trichophyton equinum, trichophyton rubrum, and trichophyton tonsurans) and a dimorphic fungus, paracoccidioides brasiliensis, and performed phylogenetic analyses. the identified mat locus idiomorphs of m. gypseum control cell t ... | 2010 | 19880755 |
| dynamics of dermatophytosis frequency in mexico: an analysis of 2084 cases. | we analysed 15,101 biological samples from patients presenting with superficial mycoses who attended outpatient services over a 10-year period. scale samples were processed for direct microscopic examination with 15% koh and cultured on sabouraud glucose agar plus chloramphenicol and cycloheximide. laboratory examination confirmed 4,709 cases of superficial mycosis (31.18%), of which 2,084 (44.26%) were dermatophytoses. the species most frequently encountered was trichophyton rubrum (71.2%), fol ... | 2010 | 19886762 |
| diagnostic pcr tests for microsporum audouinii, m. canis and trichophyton infections. | since traditional diagnosis of dermatophyte infections is slow, we present a rapid new pcr test for detection of trichophyton spp., microsporum canis and m. audouinii infections. the performance of the test was evaluated with: 58 dermatophyte isolates; 10 yeast, mould and human dna control samples; 25 routine specimens from patients suspected of having dermatophytosis; 10 hair specimens from guinea pigs experimentally infected with m. canis; and two samples from un-infected control animals. dna ... | 2010 | 19886764 |
| evaluation of a pcr melting profile method for intraspecies differentiation of trichophyton rubrum and trichophyton interdigitale. | in order to identify the source of infections caused by dermatophytes, as well as the pathogen transmission pathway, there is a need to determine methods that allow detailed genetic differentiation of the strains within the dermatophyte genera. in this work, a pcr melting profile (pcr-mp) technique based on the ligation of adaptors and the difference in melting temperatures of dna restriction fragments was used for the first time for intraspecies genotyping of dermatophytes. clinical isolates an ... | 2010 | 19892858 |
| intraspecific variation and interspecific differences in the bacterial and fungal assemblages of blue tit (cyanistes caeruleus) and great tit (parus major) nests. | although interest in the relationship between birds and microorganisms is increasing, few studies have compared nest microbial assemblages in wild passerines to determine variation within and between species. culturing microorganisms from blue tit (cyanistes caeruleus) and great tit (parus major) nests from the same study site demonstrated diverse microbial communities with 32 bacterial and 13 fungal species being isolated. dominant bacteria were pseudomonas fluorescens, pseudomonas putida, and ... | 2010 | 19830477 |
| majocchi's granuloma caused by microsporum canis in an immunocompetent patient. | 2010 | 19832861 | |
| extensive neonatal dermatophytoses. | we report a 25-day-old boy who was referred to our dermatology unit for evaluation of extensive annular erythematous lesions on his body. we initially considered the differential diagnoses of candidiasis and neonatal lupus erythematosus but investigations revealed the case as tinea corporis due to a relatively uncommon causative agent, microsporum gypseum. to the best of our knowledge it is the first case of extensive neonatal dermatophytoses caused by this organism. the possible causes and the ... | 2010 | 19686303 |
| evaluation of internal transcribed spacer 2-rflp analysis for the identification of dermatophytes. | a total of 95 isolates, belonging to 33 species of five dermatophyte genera, i.e. arthroderma (15 species), chrysosporium (two), epidermophyton (one), microsporum (three) and trichophyton (12), were studied using internal transcribed spacer 2 (its2)-pcr-rflp analysis (its2-rflp), consisting of amplification of the its2 region, restriction digestion with bstui (cg/cg) and restriction fragment length determination by capillary electrophoresis. its2-rflp analysis proved to be most useful for identi ... | 2010 | 19779030 |
| [infection with a rare geophilic dermatophyte]. | there are 12 dermatologically relevant microsporum (m.) species. the most frequent species are m. canis, m. audouinii and m. gypseum. we report an infection of the right forearm with the rare dermatophyte m. fulvum. a koh examination of scales revealed a tinea corporis. the scales were cultured on dermasel(r) agar with the identification of the geophilic dermatophyte m. gypseum. however, its sequencing and mass spectrometry revealed m. fulvum as the correct pathogen. | 2010 | 19680615 |
| evaluation of a single-tube real-time pcr for detection and identification of 11 dermatophyte species in clinical material. | we developed a dermatophyte-specific single-tube real-time pcr assay based on internal transcribed sequences. this assay allows the rapid detection and identification of 11 clinically relevant species within the three dermatophyte genera trichophyton, microsporum and epidermophyton in nail, skin and hair samples within a few hours. analysis of 145 clinical samples (107 nail, 36 skin scale, and two hair) by both real-time pcr and a pcr-reverse line blot (pcr-rlb) assay described earlier revealed ... | 2010 | 19624518 |
| management of tinea capitis in childhood. | tinea capitis (tc) is a common dermatophyte infection affecting primarily prepubertal children. the causative pathogens belong to only two genera: trichophyton and microsporum. although there is a great local variation in the epidemiology of tc worldwide, t. tonsurans is currently the most common cause of tc with m. canis second. even though there is an emerging number of anthropophilic scalp infections, m. canis remains the predominant causative organism in many countries of the mediterranean b ... | 2010 | 21437064 |
| tinea corporis caused by microsporum gallinae: first clinical case in japan. | we report herein a case of tinea corporis caused by microsporum gallinae in a 96-year-old, otherwise healthy japanese man. the patient had a long working history as a breeder of fighting cocks, and he suffered from two erythematous macules after being bitten by a cock. m. gallinae was identified as the infectious agent based on the morphology of isolates cultured on slides and analysis of dna sequences of the internal transcribed spacers (its) from ribosomal dna from cultured isolates. the patie ... | 2010 | 21352324 |
| total synthesis and antimicrobial activity of a natural cycloheptapeptide of marine origin. | the present study deals with the first total synthesis of the proline-rich cyclopolypeptide stylisin 2 via a solution phase technique by coupling of the boc-l-pro-l-ile-l-pro-oh tripeptide unit with the l-phe-l-pro-l-pro-l-tyr-ome tetrapeptide unit, followed by cyclization of the resulting linear heptapeptide fragment. the chemical structure of the finally synthesized peptide was elucidated by ftir, ¹h/¹³c-nmr and fab ms spectral data, as well as elemental analyses. the newly synthesized peptide ... | 2010 | 20948913 |
| treatment of tinea capitis - a critical appraisal. | griseofulvin has been introduced in 1958, ever since it remained the gold standard for the treatment of tinea capitis in the united states. despite the availability of new antifungals like terbinafine, itraconazole and fluconazole -with few exceptions not licensed for their use in children - duration of tinea capitis treatment could not be shortened. the reasons therefore are the anatomic structure of the hair follicle, the dormant sebum-production before onset of puberty, and the way of action ... | 2010 | 20969728 |
| geotrichum candidum as etiological agent of horse dermatomycosis. | fungi of the genus geotrichum are commonly found in the environment and, in some circumstances, they may cause diseases in humans and animals. although these fungi have been isolated from skin lesions of some animal species, their pathogenic role in horses remains uncertain. with the aim to investigate the role of geotrichum candidum as etiological agent of dermatomycoses, a retrospective study of 64 horses presenting skin lesions and suspected to have fungal infections was carried out. for each ... | 2010 | 20970928 |
| chemical composition and biological assays of essential oils of calamintha nepeta (l.) savi subsp. nepeta (lamiaceae). | aerial parts of wild calamintha nepeta (l.) savi subsp. nepeta growing spontaneously on the mediterranean coast (sardinia island, italy) and on the atlantic coast (portugal) were used as a matrix for the supercritical extraction of volatile oil with co(2). the collected extracts were analysed by gc-fid and gc-ms methods and their compositions were compared with that of the essential oil isolated by hydrodistillation, but the differences were not relevant. a strong chemical variability was observ ... | 2010 | 20981614 |
| gmi, a ganoderma immunomodulatory protein, down-regulates tumor necrosis factor α-induced expression of matrix metalloproteinase 9 via nf-κb pathway in human alveolar epithelial a549 cells. | matrix metalloproteinase 9 (mmp-9) has been implicated in airway injury in chronic obstructive pulmonary disease (copd), lung inflammation, and lung cancer and plays a major role in tumor necrosis factor-α (tnf-α)-stimulated tumor invasion and lung inflammation. mmp-9 activity is promoted by the pro-inflammatory cytokine tnf-α. gmi, cloned from ganoderma microsporum and purified, is one of the recombinant fungal immunomodulatory proteins. to understand the molecular mechanisms involved in the su ... | 2010 | 21028821 |
| composition of a volatile extract of eryngium duriaei subsp. juresianum (m. laínz) m. laínz, signalised by the antifungal activity. | the composition of a volatile extract of eryngium duriaei subsp. juresianum, signalised by the antifungal activity (mic values=0.16-0.32 μl ml(-1)) against several dermatophyte species (trichophyton mentagrophytes, t. rubrum, epidermophyton floccosum; t. verrucosum, t. mentagrophytes var interdigitale, microsporum canis and m. gypseum) was established following a combined methodology of gc, gc-ms and an exclusive (13)c nmr technique that does not require prior isolation of compounds. twenty-five ... | 2010 | 21036502 |
| effects of temperature variations and light exposure on the time to growth of dermatophytes using six different fungal culture media inoculated with laboratory strains and samples obtained from infected cats. | in this study, 5/6 commercially available fungal culture media were comparable with respect to first growth, first colour change, and first sporulation when inoculated with three strains of microsporum canis, one strain of microsporum gypseum, and one strain of trichophyton species when incubated at either 25°c or 30°c. five of six plates showed 100% growth at both temperatures. five of six plates showed 100% growth when inoculated with naturally infective m canis hairs and spores. one commercia ... | 2010 | 21051255 |
| dermatophytic pseudomycetomas in four cats. | the aim of this retrospective study was to describe the clinical characteristics and treatment of four cats with dermatophytic pseudomycetoma. four persian cats, one female and three males, with age ranging from 1.4 to 5 years, were diagnosed with dermatophytic pseudomycetoma by histological examination and fungal culture. wood's lamp examination revealed positive fluorescence of hairs in all four cats. characteristic skin lesions consisted of multifocal, raised, firm and nodular to dome-shaped ... | 2010 | 21114561 |
| isolation of dermatophytes from dogs and cats with suspected dermatophytosis in western turkey. | the aim of this study was to determine the species of dermatophytes isolated from dogs and cats and their prevalence in the two big provinces of western turkey. a total of 362 animals (198 dogs and 164 cats) with skin lesions (alopecia and desquamation) were examined from march 2006 to february 2008. of the 362 samples examined, 52 (14.4%) were positive for fungal elements by direct microscopic examination, and 70 (19.3%) were culture positive for dermatophytes. the isolation rates of dermatophy ... | 2010 | 21126787 |
| sequenced dermatophyte strains: growth rate, conidiation, drug susceptibilities, and virulence in an invertebrate model. | although dermatophytes are the most common cause of fungal infections in the world, their basic biology is not well understood. the recent sequencing and annotation of the genomes of five representative dermatophyte species allows for the creation of hypotheses as to how they cause disease and have adapted to their distinct environments. an understanding of the microbiology of these strains will be essential for testing these hypotheses. this study is the first to generally characterize these fi ... | 2010 | 21145410 |
| the spectrum of dermatological disorders among primary school children in dar es salaam. | dermatologic disorders are common in many countries but the spectrum varies greatly. many studies have reported a significant burden of skin diseases in school children. the objective of this study was to determine the current spectrum of dermatological disorders in primary school children in dar es salaam city. | 2010 | 21162714 |
| [clinical problems in medical mycology: problem number 42]. | 2010 | 21167299 | |
| dipteran-associated harpellales from lowland and submontane tropical rain forests of veracruz (mexico). | we report on the species of harpellales found in dipteran hosts during two surveys (32 field d) in the state of veracruz, mexico. one new morphospecies, genistellospora dorsicaudata, is described with particular attention to the position of the terminal cell associated with fully developed fertile thalli bearing sexual spores. we emend the description of g. guanacastensis to include morphometrics on the zygospores, based on discovery of the sexual spores for that species in our collections. thir ... | 2010 | 21186326 |
| tinea capitis in an adult patient under treatment with trastuzumab. | 2010 | 20557467 | |
| antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from superficial skin infection. | antimicrobial activity of solvent extracts of leaves and shoot of dodonaea viscosa jacq have been determined against fungi, aspergillus niger, aspergillus flavus, paecilomyces varioti, microsporum gypseum, and trichophyton rubrum causing skin diseases. all crude extracts were found to be effective against tested fungi. however chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous extracts. more over in present study some basic elements ... | 2010 | 20566450 |
| epidemiology and risk factors for dermatophytoses in rabbit farms. | while dermatophytoses of several animal species have been extensively investigated, information on their occurrence and epidemiology in rabbits is limited. we carried out a study from october 2006 to february 2007 of 23 rabbit farms in apulia and basilicata regions (southern italy) in order to investigate the occurrence and risk factors associated with dermatophytoses in breeding rabbits. dermatophytes were isolated from 86.9% (20/23) of the farms and from 51.8% (420/810) of the animals sampled. ... | 2010 | 20297949 |
| superficial fungal infections seen at a tertiary health centre: clinical and mycological studies. | superficial fungal infections are common in the tropics, partly due to the climate, relatively poor hygiene, and lifestyle of the people. | 2010 | 20931516 |
| microsporum audouinii tinea capitis in a swiss school: assessment and management of patients and asymptomatic carriers. | we report three cases involving 7- to 8-year-old children from a swiss school who had refractory tinea capitis due to an unusual strain of microsporum audouinii which perforates hair in vitro. the patients showed no response to modern oral antifungal drugs like terbinafine and fluconazole. after switching to oral griseofulvin, two of the patients had a complete recovery, while the third was cured after the introduction of oral itraconazole. given the high potential for contagion of this anthropo ... | 2010 | 20936914 |
| tinea pseudoimbricata caused by m. gypseum associated to crusted scabies. | tinea pseudoimbricata is related to t. tonsurans and t. rubrum and crusted scabies is a highly contagious dermatosis caused by excessive proliferation of s. scabiei var. hominis. we described a case of a 21-year-old patient, seronegative for hiv, with both skin diseases. the occurrence of these dermatosis simultaneously in immunocompetent patients is very rare. | 2010 | 20944921 |
| extracellular protease expression in microsporum gypseum complex, its regulation and keratinolytic potential. | two soil isolates of microsporum gypseum were studied for the production of extracellular proteases. both the strains secreted protease on glucose-gelatin medium. the enzyme activity peaked on day 15 at 28 °c. asparagine repressed protease yield. sugars caused catabolite repression of protease formation. protease activities of both the isolates were significantly affected by incubation period, culture media and carbohydrates used. both the strains grew on the skin bait and caused a gravimetrical ... | 2010 | 20946260 |
| microsporum canis antifungal susceptibilities: concerns regarding their clinical predictability. | 2010 | 20685087 | |
| dermatophytes in republic of macedonia. | (full text is available at http://www.manu.edu.mk/prilozi). a total of 1742 clinically suspected samples was examined for the incidence and distribution of dermatophytes in the republic of macedonia from june 2007 to jan. 2009. 600 dermatophytes were isolated and identified. in the studied period 9 different dermatophyte species were isolated, namely trichophyton rubrum (48.83%), microsporum canis (20%), trichophyton mentagrophytes var. interdigitale (16.83%), epidermophyton floccosum (4.17%), t ... | 2010 | 20693949 |
| strange formation of n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one and its oxime derivative--synthesis, stereochemistry, antibacterial and antifungal activity. | objectives and methods: a collection of novel n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one oximes 28-32 are synthesized, characterized by melting point, elemental analysis, ms, ft-ir, one-dimensional nmr (1h & 13c) and two dimensional noesy spectroscopic data and evaluate for their in vitro antibacterial and antifungal activities. results and conclusion: compound 32, exerted a wide range of antibacterial activities against the entire tested gram-positive and gram-negative bacterial strains e ... | 2010 | 20707249 |
| in vitro profiling of pramiconazole and in vivo evaluation in microsporum canis dermatitis and candida albicans vaginitis laboratory models. | the triazole antifungal pramiconazole (stiefel, a gsk company) was compared with itraconazole, miconazole, and terbinafine in vitro and in vivo. potent in vitro activities against candida spp. (50% inhibitory concentration [ic₅₀], 0.04 to 1.83 μm) and microsporum and trichophyton spp. (ic₅₀, 0.15 to 1.34 μm) were obtained but not, however, against other filamentous molds and zygomycetes. in the m. canis guinea pig model and c. albicans vulvovaginitis rat model, pramiconazole was superior to the ... | 2010 | 20805398 |
| efficacy of eight commercial formulations of lime sulphur on in vitro growth inhibition of microsporum canis. | lime sulphur is a common topical treatment for dermatophytosis in animals. until recently, a single veterinary lime sulphur formulation was available. the purpose of this study was to compare the efficacy of eight lime sulphur products for in vitro growth inhibition of microsporum canis using the isolated infected spore model. infective m. canis spores were isolated from hairs collected from untreated cats. hairs were macerated in triton-x solution and isolated according to a previously publishe ... | 2010 | 20868396 |
| dermatophytosis in western africa: a review. | dermatophytic fungal infections are one of the most common infectious diseases in the world and are among the most commonly diagnosed skin diseases in africa. they are caused by several dermatophyte species made up of three genera: trichophyton, microsporum and epidermophyton. the pathogen spectrum and the clinical manifestations are totally different from those seen in other continents. the hot and humid environment in africa is probably the major reason for their high prevalence. in this era o ... | 2010 | 21717868 |
| antagonism of microsporum species by soil fungi. | eighteen fungi isolated from soil by hair bating method were tested against soil inhabiting microsporum equinum, microsporum fulvum, microsporum gypseum and microsporum racemosum for their antagonistic interactions. colony inhibition during dual cultures showed inhibition of all the four microsporum species. the maximum inhibition of m. equinum, m. fulvum, m. gypseum and m. racemosum was caused by chrysosporium keratinophilum, chrysosporium tropicum, curvularia lunata and chrysosporium lucknowen ... | 2010 | 19207833 |
| tinea capitis among children in the columbus area, ohio, usa. | tinea capitis is a fungal infection of the hair follicles of the scalp. in the us, the most common organisms have traditionally been trichophyton tonsurans, and occasionally microsporum canis. this study was designed to examine patterns of organisms causing tinea capitis and determine factors associated with infection. a retrospective database analysis was conducted to locate records of patients with tinea capitis from may 2001 to may 2006 at nationwide children's hospital in columbus, oh. descr ... | 2010 | 19302461 |
| dermatophyte species in superficial mycoses in the kraków district, poland in the years 1972-2007. | considerable changes in the dermatophyte spectrum have been observed in the past century. hence, many authors point out the necessity of performing periodical overviews of the mycological flora producing mycoses in humans in a given area. analysis of dermatophyte species was performed, which were isolated from the lesions in patients suspected of superficial mycosis and referred to the department of mycology. the materials were isolated from patients suspected of superficial mycosis from kraków ... | 2010 | 19298357 |
| tinea corporis caused by an unusual strain of microsporum audouinii that perforates hair in vitro. | we report on a dermatophyte infection acquired by a young woman from germany who had worked in ghana. the strain isolated from her skin lesions showed morphological and physiological features compatible with microsporum audouinii but a clearly positive hair perforation test made its definite identification by conventional methods equivocal. a genetic analysis finally unambiguously revealed microsporum audouinii. this is the first observation of a microsporum audouinii strain with a positive hair ... | 2010 | 19538519 |
| antifungal activity of bis-azasqualenes, inhibitors of oxidosqualene cyclase. | the antifungal activity and in vitro toxicity toward animal cells of two inhibitors of oxidosqualene cyclase, squalene bis-diethylamine (sbd) and squalene bis-diethylmethylammonium iodide (sbdi) were studied. minimum inhibitory concentration (mic) against dermatophytes and other fungi involved in cutaneous and systemic infections (12 isolates from seven species) were determined by the broth microdilution method based on the reference documents m38-a and m27-a2 of clinical and laboratory standard ... | 2010 | 19549106 |
| antimicrobial activity of hymenaea martiana towards dermatophytes and cryptococcus neoformans. | the biological activity of crude extract and fractions of hymenaea martiana was evaluated against a panel of human pathogenic fungi. the crude extracts and hydroalcoholic fractions (e) showed a high activity against cryptococcus neoformans species complex isolates with mics between 2 and 64 μg ml(-1). the methanolic (c) and butanolic (d) fractions were the most active against trichopyton rubrum, trichopyton mentagrophytes and microsporum canis with mics between 8 and 256 μg ml(-1). none of the e ... | 2010 | 19563478 |
| a 20-year survey of tinea faciei. | tinea faciei is an uncommon dermatophytosis affecting the glabrous skin of the face. between 1988 and 2007 at the dermatology department of cagliari university, 107 cases of tinea faciei have been diagnosed, involving 72 females and 35 males, aged 2-72 years. incidence peaks were observed between 6 and 15 years (48.59%) and between 36 and 45 years (17.76%). males below and females above 15 years of age were the most affected. in 61 patients (57.1%), typical forms of tinea faciei were observed, w ... | 2010 | 19563490 |
| [tinea of the eyebrows. about six cases]. | tinea of the eyebrows is a part of tinea capitis. m. canis, t. violaceum, t. verrucosum and t. mentagrophytes are the most frequently implicated fungi in tinea of the eyebrows. | 2009 | 19569609 |
| dermatophytes, related keratinophilic and opportunistic fungi in indoor dust of houses and hospitals. | dermatophytes, related keratinophilic and opportunistic fungi were isolated from indoor dust samples of 46 hospitals and 47 houses in kanpur. a total of 19 fungi represented by 11 genera were isolated by the hair-baiting technique from 230 and 235 samples from hospitals and houses respectively. the isolated fungi are acremonium implicatum (indian type culture collection) itcc 5266, a. strictum (germplasm centre for keratinophilic fungi) gpck 1137, aphanoascus fulvescens gpck 1081, arthroderma si ... | 2009 | 19584506 |
| in vitro activity of tachyplesin iii alone and in combination with terbinafine against clinical isolates of dermatophytes. | aim of our study was to investigate the in vitro effects of tachyplesin iii (tp), a potent disulfide-linked peptide, in dermatophytes infections, with respect to or in combination with terbinafine (terb), against 20 clinical isolates of dermatophytes belonging to four species. a broth microdilution method following the clsi recommendations (m38-a) was used for testing drugs alone and in combination. terb mics were significantly lower than those observed for tp (p<0.001). testing for antifungal a ... | 2009 | 19591887 |
| ultrastructural changes on clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, and microsporum gypseum caused by solanum chrysotrichum saponin sc-2. | worldwide, dermatophytoses represent a high percentage of all superficial mycoses. the most frequently isolated dermatophyte is trichophyton rubrum. solanum chrysotrichum is a vegetal species widely used in mexican traditional medicine to treat skin infections; its extract has been used to formulate an herbal medicinal product that is used successfully to treat tinea pedis. spirostanic saponin sc-2 from s. chrysotrichum possesses high activity against dermatophytes. the present study reports the ... | 2009 | 19551614 |
| survey of keratinophilic fungi in sewage sludge from wastewater treatment plants of mazandaran, islamic republic of iran. | to isolate keratinophilic fungi in sewage sludge from wastewater treatment plants in sari city, mazandaran province, islamic republic of iran, samples were taken from 7 plants with different sewage treatment technologies. from 35 sludge samples cultured on sabouraud's agar with cycloheximide and chloramphenicol, 326 fungal colonies belonging to 7 species were isolated. geotrichum (59.5%), cladosporium (13.8%), alternaria (11.3%) and penicillium (10.7%) species were the most prevalent. no growth ... | 2009 | 19554993 |
| antifungal and marker effects of talisia esculenta lectin on microsporum canis in vitro. | the purpose of this study was to demonstrate the usefulness of lectin obtained from talisia esculenta (tel) seeds as a tool to recognize and study microsporum canis. for this purpose, we investigated the antifungal and marker action of this lectin and the relationship of these effects with the presence of carbohydrates on the structure of this fungus. | 2009 | 19558469 |
| causative agents of superficial mycoses in istanbul, turkey: retrospective study. | the aim of the present study was to determine the percentage of agents, which can give rise to superficial fungal infections in istanbul, turkey. between 2000 and 2007, the clinical samples collected from 8,200 patients attending the outpatient dermatology clinic at mihrimahsultan medical center were examined by direct microscopy and culture. pathogen fungi were detected in 5,722 of the patients. of the isolates were 4,218 (74%) dermatophytes, 1,196 (21%) candida sp., 170 (3%) malassezia furfur, ... | 2009 | 19544086 |
| leptoglycin: a new glycine/leucine-rich antimicrobial peptide isolated from the skin secretion of the south american frog leptodactylus pentadactylus (leptodactylidae). | antimicrobial peptides are components of innate immunity that is the first-line defense against invading pathogens for a wide range of organisms. here, we describe the isolation, biological characterization and amino acid sequencing of a novel neutral glycine/leucine-rich antimicrobial peptide from skin secretion of leptodactylus pentadactylus named leptoglycin. the amino acid sequence of the peptide purified by rp-hplc (c(18) column) was deduced by mass spectrometric de novo sequencing and conf ... | 2009 | 19298834 |
| antimicrobial hasubanalactam alkaloid from stephania glabra. | a novel hasubanalactam alkaloid, named glabradine, has been isolated from the tubers of stephania glabra, together with three known quaternary protoberberine alkaloids, palmatine, dehydrocorydalmine and stepharanine. the structure of glabradine was assigned as 7-o-demethyl-n,o-dimethyloxostephinine, by means of rigorous spectroscopic analysis including 2 d nmr measurements. it was evaluated for antimicrobial activity against staphylococcus aureus, s. mutans, microsporum gypseum, m. canis and tri ... | 2009 | 19148860 |
| first case of microsporum ferrugineum from tunisia. | this is the first case of microsporum ferrugineum isolated from a tunisian patient. a 60-year-old man was admitted for tinea sycosis associated with circinate herpes of the hand. examination disclosed diffuse erythematic and perifollicular papules and pustules in the beard area. typical ringworm vesiculo-pustular lesions involved skin of the hand. isolates were identified as microsporum sp on the basis of macroscopic and microscopic colony characteristics. the diagnosis of m. ferrugineum was con ... | 2009 | 19184525 |
| [fungicidal activity of liranaftate against dermatophytes]. | the fungicidal activities of the thiocarbamate antifungal agent liranaftate were compared to those of luliconazole, amorolfine hydrochloride and ketoconazole against twelve stock strains of three species of dermatophytes. the mics of 0.001-0.009 microg/ml of luliconazole against trichophyton rubrum (n=6)were the lowest among the agents tested, but its mccs were considerably higher. consequently, the antifungal potency of luliconazole was considered fungistatic. in contrast to this, the mccs of 0 ... | 2009 | 19194054 |
| sertaconazole: a review of its use in the management of superficial mycoses in dermatology and gynaecology. | sertaconazole (dermofix, ertaczo, ginedermofix, monazol, mykosert or zalain), an imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi. it is indicated in the eu for the treatment of superficial skin mycoses such as dermatophytosis (including tinea corporis, tinea cruris, tinea manus, tinea barbae and tinea pedis), cutaneous candidiasis, pityriasis versicolor and seborrhoeic dermatitis of the scalp, and in the us for tinea pedis only. sertaco ... | 2009 | 19275277 |
| design of conformationally constrained azole antifungals: efficient synthesis and antifungal activity of trans-3-imidazolylflavanones. | an efficient protocol has been developed for the preparation of a series of trans-3-imidazolylflavanones and (z)-trans-3-imidazolylflavanone oximes, as potential antifungal agents, by the reaction of 2-imidazolyl-2'-hydroxyacetophenone with different benzaldehyde derivatives and subsequence oximation reaction. the stereochemical and conformational aspects of compounds were also assigned by (1)h nmr spectroscopy. the aryl group present at c-2 and the imidazole ring present at c-3 were assigned to ... | 2009 | 19291101 |
| antioxidant and antidermatophytic activities of essential oil and extracts of metasequoia glyptostroboides miki ex hu. | this study was undertaken to assess the antioxidant and antidermatophytic potential of the essential oil and extracts (hexane, chloroform, ethyl acetate and methanol) of metasequoia glyptostroboides miki ex hu. antioxidant activity was evaluated by using 1,1-diphenyl-2-picrylhydrazyl (dpph) assay. the free radical scavenging activities of the oil and ethyl acetate extract were found to be superior (ic(50)=9.1 and 14.24 microg/ml, respectively) as compared to butylatedhydroxyanisole (bha), (ic(50 ... | 2009 | 19303043 |
| production of peptide antifungal antibiotic and biocontrol activity of bacillus subtilis. | among different bacterial cultures, a potent bacillus subtilis mtcc-8114 was isolated from garden soil samples which showed 16 and 14 mm inhibition zones by spot inoculation method and 24 and 22 mm inhibition zones by well agar diffusion method against test fungi i.e. microsporum fulvum and trichophyton species. among four media tested, the maximum growth and antibiotic production was found in trypticase soya broth (tsb) medium at 37 degrees c, ph-7 and 48 h of incubation. the rf value (0.64) by ... | 2009 | 19317353 |
| clinico-etiologic correlates of onychomycosis in sikkim. | the etiological spectrum of any superficial mycosis is largely dependent on the flora in the immediate environment of the individual. it is influenced by the geographic, climatic and occupational factors. the study is basically to formulate baseline data for the species prevalence of various dermatophytes in patients with onychomycosis attending the central referral hospital, gangtok, sikkim. | 2009 | 19332910 |
| antimicrobial dihydroisocoumarins from crassocephalum biafrae. | bioassay-guided fractionation of the chcl (3)-soluble extract of the stem bark of crassocephalum biafrae (asteraceae) resulted in the isolation of three new dihydroisocoumarins, named biafraecoumarins a ( 1), b ( 2), and c ( 3); two known triterpenes ( 4 and 5); and a known ceramide ( 6). the structures of the new compounds were established as 7-but-15-enyl-6,8-dihydroxy-3( r)-penta-9,11-dienylisochroman-1-one ( 1), 7-butyl-6,8-dihydroxy-3( r)-penta-9,11-dienylisochroman-1-one ( 2), and 7-butyl- ... | 2009 | 19350487 |
| diagnosis: dermatophytid reaction (id reaction). commentary. | 2009 | 19367834 | |
| growth, keratinolytic proteinase activity and thermotolerance of dermatophytes associated with alopecia in uyo, nigeria. | mycological research was conducted on the mycelial growth, keratinolytic proteinase activity and thermotolerance ofdermatophytes associated with alopecia patients in uyo, nigeria. the results revealed that microsporum sp. - ap1, epidermophyton sp. - ap2, trichophyton rubrum - ap4, trichophyton mentagrophytes - ap5 and a yeast candida albicans - ap3 isolated exhibited variable growth and keratinase activity at different temperatures. microsporum sp. - ap1 and t. mentagrophytes - ap5 survived heat ... | 2009 | 19388557 |
| heat resistance of dermatophyte's conidiospores from athletes kits stored in nigerian university sport's center. | the incidence and heat resistance of conidiospores produced by dermatophytes isolated from athlete's kits (canvasses, stockings and spike shoes) stored in nigerian university sport's centre were investigated. epidermophyton floccosum, microsporum oudouinii, microsporum canis, trichophyton concentricum, trichophyton mentagrophytes and trichophyton rubrum were isolated and their incidence on the athlete's kits varied with the species and type of kits. among the isolates t. mentagrophytes, t. rubru ... | 2009 | 19388558 |
| canine nodular dermatophytosis (kerion): 23 cases. | dermatophytosis is a common zoonotic disease, and one of its clinical presentations in the dog is nodular dermatophytosis (kerion). because the infection is located within the dermis, routine diagnostic tests such as a wood's lamp examination, microscopic examination of hair shafts for fungal elements and fungal culture can yield negative results. in such cases, histopathological examination with routine and special stains (periodic acid-schiff, gomori methenamine silver) is required to confirm ... | 2009 | 19392766 |
| antifungal potential of essential oil and various organic extracts of nandina domestica thunb. against skin infectious fungal pathogens. | this study was undertaken to assess the in vitro antifungal potential of the essential oil and n-hexane, chloroform, ethyl acetate, and methanol extracts of nandina domestica thunb. against dermatophytes, the casual agents of superficial infections in animals and human beings. the oil (1,000 microg/disc) and extracts (1,500 microg/disc) revealed 31.1-68.6% and 19.2-55.1% antidermatophytic effect against trichophyton rubrum kctc 6345, t. rubrum kctc 6375, t. rubrum kctc 6352, trichophyton mentagr ... | 2009 | 19415265 |
| antimicrobial activity of acacia mellifera extracts and lupane triterpenes. | acacia mellifera (vahl) benth (leguminosae) is a subtropical medicinal plant that is widely used in traditional african medicines against various diseases such as pneumonia and malaria. | 2009 | 19429353 |
| nb-002, a novel nanoemulsion with broad antifungal activity against dermatophytes, other filamentous fungi, and candida albicans. | nb-002 is an oil-in-water emulsion designed for use for the treatment of skin, hair, and nail infections. the activity of nb-002 was compared to the activities of the available antifungal drugs against the major dermatophytes responsible for cutaneous infections, trichophyton rubrum, trichophyton mentagrophytes, epidermophyton floccosum, and microsporum spp., as well as 12 other genera of filamentous fungi. nb-002 consistently displayed fungicidal activity against all dermatophytes. the comparat ... | 2009 | 19433562 |
| antimicrobial activity of the crude extract, fractions and compounds from stem bark of ficus ovata (moraceae). | this study was designed to investigate the antimicrobial activities of the methanol extracts from the stem bark of ficus ovata (fob), fractions (fob1-6) and compounds isolated following bio-guided fractionation [3-friedelanone (1), taraxeryl acetate (2), betulinic acid (3), oleanoïc acid (4), 2-hydroxyisoprunetin (5), 6,7-(2-isopropenyl furo)-5,2,4-trihydroxyisoflavone (6), cajanin (7) and protocatechuic acid (8)]. | 2009 | 19450673 |
| tinea capitis in early infancy treated with itraconazole: a pilot study. | tinea capitis is the most common fungal infection of the scalp in childhood, but a very rare disorder in the first year of life. | 2009 | 19453785 |
| recent dermatophyte divergence revealed by comparative and phylogenetic analysis of mitochondrial genomes. | dermatophytes are fungi that cause superficial infections of the skin, hair, and nails. they are the most common agents of fungal infections worldwide. dermatophytic fungi constitute three genera, trichophyton, epidermophyton, and microsporum, and the evolutionary relationships between these genera are epidemiologically important. mitochondria are considered to be of monophyletic origin and mitochondrial sequences offer many advantages for phylogenetic studies. however, only one complete dermato ... | 2009 | 19457268 |
| epidemiology of fungal scalp infections in the west of scotland 2000-2006. | fungal infections of the scalp commonly affect the paediatric population and are caused by dermatophytes which have the ability to invade the keratinised structures of skin, hair and nails. this study analyses the changes in the epidemiology of fungal scalp infections in the west of scotland during the period 2000-2006. | 2009 | 19530495 |
| epidemiology of dermatophytoses in sfax, tunisia. | the distribution of dermatophytes varies in different countries and geographical areas depending on several factors. to determine the frequency of aetiological agents and the clinical variants of dermatophytoses, we carried out a study between 1998 and 2007. out of 25 432 subjects suspected to have superficial mycoses, 9960 (39.2%) were affected with dermatophytoses; 14957 positive samples were obtained. the mean age was 35.7 years (range: 21 days to 97 years). sex ratio was 0.9. our patients we ... | 2009 | 19207834 |
| in vitro pharmacodynamic characteristics of griseofulvin against dermatophyte isolates of trichophyton tonsurans from tinea capitis patients. | tinea capitis is the most commonly observed fungal infection in childhood and is primarily caused by the dermatophyte species trichophyton tonsurans, microsporum canis, and trichophyton violaceum. in north america and the united kingdom t. tonsurans is responsible for more than 90% of cases. griseofulvin has been the treatment of choice for tinea capitis for more than 40 years and is the sole oral antifungal agent approved by the fda for the management of tinea capitis. some researchers have exp ... | 2009 | 19212895 |
| in vitro susceptibility testing of dermatophytes isolated in goiania, brazil, against five antifungal agents by broth microdilution method. | the antifungal activities of fluconazole, itraconazole, ketoconazole, terbinafine and griseofulvin were tested by broth microdilution technique, against 60 dermatophytes isolated from nail or skin specimens from goiania city patients, brazil. in this study, the microtiter plates were incubated at 28 masculinec allowing a reading of the minimal inhibitory concentration (mic) after four days of incubation for trichophyton mentagrophytes and five days for t. rubrum and microsporum canis. most of th ... | 2009 | 19229384 |
| relation between lipophilicity of alkyl gallates and antifungal activity against yeasts and filamentous fungi. | the antifungal activity of a complete series of 15 n-alkyl gallates and six analogues acting against a representative panel of opportunistic pathogenic fungi was studied in order to analyze their role in: the importance of the fungi tested, the importance of the hydroxyls, the influence of the chain length and the hydrophobicity of the compounds. it was demonstrated that dermatophytes were the most susceptible species and that hydroxyls appear to be necessary but not sufficient for the activity. ... | 2009 | 19232493 |
| competence of the housefly, musca domestica, as a vector of microsporum canis under experimental conditions. | the role of musca domestica linnaeus as a vector of the dermatophyte microsporum canis was investigated under experimental laboratory conditions. about 400 4-day-old m. domestica flies were divided into two groups. group a consisted of about 200 infected flies and group b comprised about 200 uninfected flies that were used as controls. each trial was run three times. flies from group a were fed for 24 h with a solution of ultra-high temperature-treated (uht) milk containing about 10(6) colony-fo ... | 2009 | 19239611 |
| changing face of tinea capitis in europe. | the aim of this review is to update the latest epidemiological situation in europe, explore recent issues in recognition and emerging opportunities in diagnosis and look at progressions in treatment. papers reviewed have, in the main, been published within the last 2 years. | 2009 | 19262376 |
| thymoquinone inhibits germination of dermatophyte arthrospores. | 2009 | 19271082 | |
| dermatophyte infections in cairo, egypt. | in this study, we examined dermatophyte infections in patients referred to the department of dermatology, el-houd el-marsoud hospital, cairo, during march 2004 to june 2005. of 506 patients enrolled in this investigation, 403 (79.6%) were clinically diagnosed as having dermatophytoses (age range 6-70 years; males 240; females 163). species identification determined by observation of their macroscopic and microscopic characteristics was complemented with sequencing of the internal transcribed spa ... | 2009 | 18972221 |
| design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome p450 14alpha-demethylase. | based on the results of computational docking to the active site of the cytochrome p450 14alpha-demethylase (cyp51), a series of 1-(1h-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols as analogs of fluconazole were designed, synthesized, and evaluated as antifungal agents. the mic(80) values indicate that compounds 1a-n exhibited higher activity against nearly all fungi tested except aspergillus fumigatus than fluconazole, while compounds 2a-f, 3a-f showed no activity or onl ... | 2009 | 19097674 |
| anti-fungal efficacy of polybutylcyanoacrylate nanoparticles of allicin and comparison with pure allicin. | although garlic has been used in chinese traditional medicine for its medical properties for thousands of years, investigations into its mode of action are relatively recent. the purpose of this study was to evaluate the in vitro anti-fungal efficacy of the active principle of garlic, pure allicin and polybutylcyanoacrylate (pbca) nanoparticles (nps) loaded with allicin. pure allicin was prepared by reacting synthetic alliin with a stabilized process of the garlic enzyme alliinase. pbca nps were ... | 2009 | 19105898 |
| in vitro susceptibility of dermatophytes to conventional and alternative antifungal agents. | the minimum inhibitory concentrations (mics), the minimal fungicidal concentrations (mfcs), the fungal biomass (fb) and hyphal viability employing the dye 3-4,5 dimethyl- 2-thiazolyl- 2,5- diphenyl- 2h tetrazolium bromide (mtt) were used to compare the in vitro effects of fluconazole (flu) with those of the n-terminal palmitoyl-lipidated peptide, pal-lys-lys-nh(2) (pal), and a tea tree oil component, gamma-terpinene (ter), against several clinical isolates of microsporum canis and trichophyton r ... | 2009 | 19115137 |
| the emergence of trichophyton tonsurans in port-au-prince, haiti. | the occurrence of the anthropophilic dermatophyte trichophyton tonsurans as a frequent causative agent of tinea capitis in several developed countries has been associated with a global rise in its isolation during recent years. while t. tonsurans was never found in haiti before 1988, a sharp increase in the number of isolates of this species from scalp lesions began to be observed in 2005 in port-au-prince, haiti. a prospective study was conducted in port-au-prince from may to november 2006 of 6 ... | 2009 | 18608887 |