Publications

locomotor activity in common spiny mice (acomys cahirinuse): the effect of light and environmental complexity.	rodents typically avoid illuminated and open areas, favoring dark or sheltered environments for activity. while previous studies focused on the effect of these environmental attributes on the level of activity, the present study tested whether the spatio-temporal structure of activity was also modified in illuminated compared with dark and complex compared with open arenas. for this, we tested common spiny mice (acomys cahirinus) in empty or stone-containing arenas with lights on or lights off.	2004	15537426
differential energy costs of winter acclimatized common spiny mice acomys cahirinus from two adjacent habitats.	the common spiny mouse acomys cahirinus, of ethiopian origin, has a widespread distribution across arid, semi-arid and mediterranean parts of the arabian sub-region. we compared the daily energy expenditure (dee), water turnover (wto) and sustained metabolic scope (susms=dee/resting metabolic rate) of two adjacent populations during the winter. mice were captured from north- and south- facing slopes (nfs and sfs) of the same valley, comprising mesic and xeric habitats, respectively. both dee and ...	2004	15123215
anatomical and histological data on the ciliary ganglion in the egyptian spiny mouse (acomys cahirinus desmarest).	the morphology and topography of the ciliary ganglion in the egyptian spiny mouse were studied with use of histochemical and histological techniques. the ciliary ganglion of the egyptian spiny mouse consisted of between 3 and 4 agglomerations of nerve cells. the largest was situated at the point where the ventral branch of the oculomotor nerve divides into two branches. the next two smaller aggregations were located on the superior and lateral surfaces of the optic nerve where it crossed the ocu ...	2004	15478100
a comparative study on cardiac ganglia in midday gerbil, egyptian spiny mouse, chinchilla laniger and pigeon.	using the thiocholine method and histological techniques, the topography and morphology of cardiac ganglia in midday gerbil, egyptian spiny mouse, chinchilla laniger and pigeon were studied. the results demonstrated that cardiac ganglia in all investigated species are embedded in epicardial fat. they formed plexo-ganglionic structures. each of them composed of many ganglia (from seven up to 36) different in size and shape, and interconnected by fascicles of nerve fibres. comparative analysis sho ...	2003	12823098
human zoonotic cutaneous leishmaniasis and associated sand flies (diptera: psychodidae) in sheikh atiya village, southern sinai, egypt.	zoonotic cutaneous leishmaniasis is endemic in sinai peninsula. human cases were recorded from the northern sinai, however little was known about the disease in southern sinai. during entomological surveys conducted southern sinai in summers of 1997-1999, a clinically confirmed zcl case was encountered for the first time in sheikh atiya village in june 1999. the parasite was isolated and identified as l. major using cellulose acetate electrophoresis. a total of 784 phlebotomine sand flies were c ...	2003	14708854
host specificity and foraging efficiency in blood-sucking parasite: feeding patterns of the flea parapulex chephrenis on two species of desert rodents.	parasite species can adapt to ecological, behavioral, physiological and biochemical traits of a particular host species. the flea parapulex chephrenis occurs on the spiny mouse acomys cahirinus, but does not occur on a co-existing gerbil, gerbillus dasyurus. to test the hypothesis that the host species affects feeding parameters of a host-specific flea, we studied the feeding rate, rate of blood digestion and resistance to starvation of p. chephrenis when feeding on a. cahirinus and g. dasyurus. ...	2003	12739133
rodents in open space adjust their behavioral response to the different risk levels during barn-owl attack.	previous studies have revealed that the response of prey species to predatory risk comprised either freezing (when the prey remained immobile), or fleeing (when it ran frantically in order to remove itself from the vicinity of the predator). other studies, however, have suggested that the prey will adjust its behavior to risk level. the present study was designed to follow the attacks of a barn owl (tyto alba) on common spiny mice (acomys cahirinus) and social voles (microtus socialis guntherei) ...	2003	14614781
local variation in helminth burdens of egyptian spiny mice (acomys cahirinus dimidiatus) from ecologically similar sites: relationships with hormone concentrations and social behaviour.	populations of egyptian spiny mice (acomys cahirinus dimidiatus) in a fragmented montane wadi system in the sinai showed significant differences in the abundance of gut helminths. differences in parasite load between populations were positively associated with measures of androgen activity but showed no significant relationship with glucocorticoid activity. social discrimination tests with adult males from different wadis showed that those from sites with greater helminth abundance were less lik ...	2003	12895278
morphology, topography and cytoarchitectonics of the pterygopalatine ganglion in egyptian spiny mouse (acomys cahirinus, desmarest).	using the thiocholine method of koelle and friedenwald and histological techniques the pterygopalatine ganglion in egyptian spiny mouse (acomys cahirinus, desmarest) was studied. the ganglion was found to be a single irregular cluster of neurocytes, situated on the medial surface of the maxillary nerve. the ganglion is composed of oval, elliptical and sometimes fusiform ganglionic neurones in compact arrangement without a thick connective-tissue capsule.	2002	12164048
comparative non-shivering thermogenesis in adjacent populations of the common spiny mouse (acomys cahirinus) from opposite slopes: the effects of increasing salinity.	we compared non-shivering thermogenesis between two adjacent populations of the common spiny mouse acomys cahirinus from different habitats, in relation to increasing salinity. individuals were captured from the north- and south-facing slopes of the same valley, that represent "mediterranean" and "desert" habitats, respectively. we hypothesized that the two populations of mice would differ in their thermoregulatory capacities, reflecting their need to cope with the environmental stress in each h ...	2002	11824399
the effects of season and dietary salt content on body temperature daily rhythms of common spiny mice from different micro-habitats.	we compared body temperature (t(b)) daily rhythms in two populations of common spiny mice, acomys cahirinus, during summer and winter months in relation to increasing dietary salt content. mice were collected from the north and south facing slopes (nfs and sfs) of the same valley, that are exhibiting mesic and xeric habitats, respectively. during the summer, whilst mice were offered a water source containing 0.9% nacl, sfs individuals had t(b) peak values at 24:00, whereas nfs individuals had pe ...	2002	12020645
the structure of the spiny mouse (acomys cahirinus) ovary during development.	the study presents the structure of the ovaries of the spiny mouse (acomys cahirinus) during the first months of life. the ovaries in neonate females exhibit a large number of primordial and primary follicles, sometimes clustered in nests. the growing follicles were also observed within the ovary at that period. the first, early antral follicles appeared in the ovary during the second week of life. in the group of 60-day old females, the structure of the ovaries was characterized by a significan ...	2002	12056623
albert renold memorial lecture: molecular background of nutritionally induced insulin resistance leading to type 2 diabetes--from animal models to humans.	albert renold strived to gain insight into the abnormalities of human diabetes by defining the pathophysiology of the disease peculiar to a given animal. he investigated the israeli desert-derived spiny mice (acomys cahirinus), which became obese on fat-rich seed diet. after a few months hyperplasia and hypertrophy of beta-cells occurred leading to a sudden rupture, insulin loss and ketosis. spiny mice were low insulin responders, which is probably a characteristic of certain desert animals, pro ...	2001	11795838
morphology, topography and cytoarchitectonics of the otic ganglion in egyptian spiny mouse (acomys cahirinus, desmarest).	using the thiocholine method of koelle and friedenwald and histological techniques, the otic ganglion in egyptian spiny mouse (acomys cahirinus, desmarest) was studied. the ganglion was found to be a single oval cluster of neurocytes, situated at the medial and posterior surface of the mandibular nerve just above the maxillary artery. the ganglion is composed of typical ganglionic neurons in compact arrangement without a thick connective-tissue capsule.	2001	11234700
audiograms of five species of rodents: implications for the evolution of hearing and the perception of pitch.	behavioral audiograms were determined for five species of rodents: groundhog (marmota monax), chipmunk (tamias striatus), darwin's leaf-eared mouse (phyllotis darwinii), golden hamster (mesocricetus auratus), and egyptian spiny mouse (acomys cahirinus). the high-frequency hearing of these animals was found to vary inversely with interaural distance, a typical mammalian pattern. with regard to low-frequency hearing, the animals fell into two groups: those with extended low-frequency hearing (chip ...	2001	11470193
temporal partitioning among diurnally and nocturnally active desert spiny mice: energy and water turnover costs.	nocturnal acomys cahirinus and diurnally active a. russatus coexist in hot rocky deserts. diurnal and nocturnal activity exposes them to different climatic challenges. a doubly-labelled water field study revealed no significant differences in water turnover between the species at all seasons, reflecting the adaptations of a. russatus to water conservation. in summers the energy expenditure of a. russatus tended to be higher than that of a. cahirinus. energy requirements of a. cahirinus in winter ...	2001	11163930
notes on mites of the family myobiidae (acari: prostigmata) parasitising rodents (mammalia: rodentia) in iran.	six mite species of the family myobiidae, radfordia (austromyobia)persica sp. n., radfordia (austromyobia) merioni bochkov, dubinina et chirov, 1990, radfordia (radfordia) acomys fain et lukoschus, 1977, radfordia (radfordia) affinis (poppe, 1896), radfordia (graphiurobia) dyromys fain et lukoschus, 1973, and myobia (myobia) murismusculi (schrank, 1781) were found in iran on the rodents gerbillus cheesmani thomas, meriones libycus lichtenstein, acomys cahirinus (desmarest), alus musculus l., dry ...	2000	10833020
intestinal helminths of spiny mice (acomys cahirinus dimidiatus) from st katherine's protectorate in the sinai, egypt.	spiny mice, acomys cahirinus dimidiatus, inhabiting the wadis close to st katherine in the mountains of the sinai peninsula, were trapped and their helminth parasites were studied. sixty one mice provided faeces for analysis and 27 were killed and autopsied. six species of helminths were recorded (the spirurid nematodes, protospirura muricola (74.1%) and mastophorus muris (11.1%), the oxyuroid nematodes, dentostomella kuntzi (59.3%), aspiculuris africana (3.7%), and syphacia minuta (3.7%) and th ...	2000	10831051
overnutrition in spiny mice (acomys cahirinus): beta-cell expansion leading to rupture and overt diabetes on fat-rich diet and protective energy-wasting elevation in thyroid hormone on sucrose-rich diet.	previous studies: the investigation of diabetes propensity in spiny mice, performed in geneva and jerusalem colonies, is reviewed. spiny mice live in semi-desert regions of the eastern mediterranean countries. those transferred to geneva in the 1950s were maintained on a rodent diet supplemented by fat-rich seeds. they became obese, exhibited pancreatic islet hyperplasia and hypertrophy. low insulin secretion response was characteristic of this species, despite ample pancreatic content of insuli ...	2000	10751749
analysis of some biophysical and biochemical parameters of long bones of spiny mouse (acomys cahirinus) in its life cycle.		1999	10353008
differential behavioural and hormonal responses of voles and spiny mice to owl calls.	rodents usually respond to the presence of owls by reducing overall activity, in particular foraging. in this study, a playback of recorded tawny owl, strix aluco, calls was sufficient to induce a marked effect in the social (gunther's) vole, microtus socialis. some of the voles exposed to owl calls reduced their activity ('freeze' pattern) unlike control voles exposed to a human voice. other voles, however, dashed around the cage ('flee' pattern). owl calls also increased corticosterone levels ...	1999	10564611
histology and enzymatic activity in the postnatal development of limb muscles in rodents.	the present work examines how increases in spontaneous motor capabilities during postnatal development are reflected in enzymatic activity and the histology of hindlimb muscles of the dormouse (eliomys melanurus), the jird (meriones tristrami), the vole (microtus socialis), and the spiny mouse (acomys cahirinus). the precocial neonate of the spiny mouse had the most advanced developmental state of young myofibers with striations as early as 1 week after delivery. at the same age, the altricial n ...	1998	9523911
photoperiodic responses of four wild-trapped desert rodent species.	the purpose of this study was to examine the effect of the photoperiod on reproductive status and body and lipid masses in four egyptian desert rodent species (dipodillus dasyurus, acomys cahirinus, gerbillus andersoni, and gerbillus pyramidum). adult males and females were housed in long days for 11 wk. at that time, one-half of the animals were killed and the remaining animals were moved to short days (sds) for 11 wk. some individuals of gerbillus andersoni and gerbillus pyramidum had access t ...	1998	9843891
intrageneric phylogeny of acomys (rodentia, muridae) using mitochondrial gene cytochrome b.	this paper investigates interspecies relationships within the genus acomys (spiny mice) by analyzing entire mitochondrial cytochrome b gene (1141 bp). this gene provides strong phylogenetic signal, as shown by high support of the topology obtained (bootstrap value and rna support number). the phylogeny is congruent with inferences from allozymes for the species considered. controversial taxonomy of acomys cahirinus, dimidiatus, airensis, and ignitus is clarified, with their specific ranks confir ...	1998	9668005
a new coccidian from acomys cahirinus desmarest, 1819, from evolution canyon, lower nahal oren, mount carmel, israel.	in 1994, fresh fecal samples were collected and examined for coccidian parasites from 43 spiny mice (acomys cahirinus) and from 60 wood mice (apodemus mystacinus). the 2 genera of rodents inhabit an area in lower nahal oren. mount carmel, israel, known as evolution canyon, which consists of opposite-facing slopes that are geologically identical, but micro-climatically very different. acomys cahirinus is found primarily on the warmer and drier south-facing slope (sfs), whereas a. mystacinus prima ...	1997	9105310
the cairo spiny mouse acomys cahirinus shows a strong affinity to the mongolian gerbil meriones unguiculatus.	the classification of the african spiny mice (genus acomys) within the muridae family of rodents has been fraught with controversy. morphological data suggest a close affinity between this group and true old world mice of the genus mus. however, the combined results of immunological, biochemical, and dna melting studies suggest that spiny mice should not even be considered as members of the murinae subfamily. to further elucidate the position of the spiny mice within the rodent phylogenetic tree ...	1996	8583903
development and consequences of insulin resistance: lessons from animals with hyperinsulinaemia.	studies involving genetically and nutritionally induced diabetes in animals indicate that early hyperinsulinaemia is the causative factor of tissue insulin resistance, leading to compensatory insulin oversecretion and pancreatic beta-cell dysfunction. the models for this syndrome, which occurs in association with obesity (thus termed "diabesity" here), concern either species with a sturdy pancreas, capable of long-lasting oversecretion, or those with labile beta cells which cannot sustain the in ...	1996	8792092
effect of passage of babesia ovis in the gerbil (acomys cahirinus) on the course of infection in splenectomized lambs.	splenectomized gerbils (acomys cahirinus) have been found to be susceptible to babesia ovis applied via blood inoculation, whereas intact gerbils were not infected. blood from splenectomized latently infected gerbils caused infection in a splenectomized lamb. intact acomys cahirinus gerbils did not become infected by b. ovis, and all captured rodents in an enzootic area, intact and splenectomized, were found to be negative for b. ovis. it can thus be concluded that acomys cahirinus does not serv ...	1996	8916410
respiratory rhythm generation in a precocial rodent in vitro preparation.	in vitro preparations for studying the neural control of respiration consisting of brainstem and spinal cord regions isolated from the newborn (po-p1) precocial rodent, acomys cahirinus (spiny mouse) are described. spiny mice have a longer gestation period (39 days) than laboratory rats (22 days) and mice (20 days) and thus are born in a considerably more mature state. we sought to determine if in vitro preparations isolated from spiny mice would spontaneously generate a respiratory motor patter ...	1996	8833542
the chromosome complement of acomys spp. (rodentia, muridae) from oursi, burkina faso--the ancestral karyotype of the cahirinus-dimidiatus group?	we present here data on chromosome banding analysis (r- and c-bands) of acomys sp. (rodentia, muridae) from oursi, burkina faso, characterized by 2n = fn = 68 and comparison of its banding patterns with those of acomys dimidiatus from saudi arabia (2n = 38, fn = 70), studied previously. the study revealed complete homology between acrocentric chromosomes of acomys sp. and chromosome arms of 16 pairs of metacentric and two pairs of acrocentric chromosomes of a. dimidiatus. in addition to monobrac ...	1996	8939364
interaction between acari ectoparasites and rodents in suez governorate, egypt.	from the medical point of view, the relation between man and rodents comes in the priority. some rodent populations are wild but others are commensal and live in close association with man. they steal his food and conveying many zoonotic diseases. their arthropod ectoparasites play an important role in conveying or transmitting these zoonotic diseases. several disorders and diseases of man are tick borne relapsing fever, rocky mountain spotted fever, lyme disease, and many others. besides numero ...	1995	7665934
biotransformation in egyptian spiny mouse acomys cahirinus.	the activities of several representative biotransformation enzymes were determined in male and female spiny mouse tissues. cytochrome p450 monooxygenase activity toward benzo(a)pyrene was significantly greater in female spiny mouse intestine than in males. activity toward benzphetamine in both sexes was high in the liver, with little activity in the kidney and intestine. sulfotransferase activity was high in kidney and intestine of female spiny mice but undetectable in the same tissues in males. ...	1995	7749597
organ-to-body weight ratio in the egyptian spiny mouse acomys cahirinus.		1994	7933979
stability of preference for odors after short-term exposure in young spiny mice.	the stability of olfactory preferences for artificial odors was studied in young spiny mouse pups (acomys cahirinus). subjects aged between 2 and 20 days were exposed to the odor of either cinnamon or cumin for 1.5 hr. the durability of preferences for the familiar versus novel odor was subsequently monitored in a three-choice preference test. the results suggest the existence of a sensitive phase for learning odor characteristics, through simple exposure, between days 2 and 18 of the pups' post ...	1993	8440404
ultrastructure of kolmer's crystalloid in the pinealocytes of the common spiny mouse (acomys cahirinus dimidiatus).	light- and electron-microscopical observations revealed a rod-like inclusion body in the pinealocytes of the common spiny mouse (acomys cahirinus dimidiatus). ultrastructurally, the body is composed of a varying number of tubes whose wall consists of thin filaments aligned in helical arrangement. the inner and outer surface of the wall is covered with ribosome-like granules. based on a morphological analysis it is concluded that the body described in the present investigation is identical with k ...	1993	8269483
daily rhythms of body temperature in acomys russatus: the response to chemical signals released by acomys cahirinus.	two species of spiny mice of the genus acomys--the golden spiny a. russatus and the common spiny a. cahirinus--are sympatric in the arid and hot parts of the rift valley in israel. the coexistence of these two species is due to exclusion of a. russatus mice by a. cahirinus mice from nocturnal activity. the aim of this research was to study if odor signals released by a. cahirinus mice can play a role in the exclusion of a. russatus mice. a. russatus mice with an implanted transmitter recording b ...	1993	8319316
larval occurrence of hydatigera taeniaeformis batsch (1786) (cestoda: taeniidae) in the liver of wild rodents in egypt.	hydatigera taeniaeformis batsch (1786) was found in the liver of six species of egyptian wild rodents. wanas et al., (1990) found the total incidence of this larval stage to be 20.0% among cestode infection. it was found in (40.9%) rattus norvegicus; (33.3%) gerbillus gerbillus; (26.8%) rattus rattus; (25.0%) mus musculus; (16.6%) acomys cahirinus; and (7.2%) arvicanthis niloticus. the cysts of hydatigera taenioformis was always occupying the marginal surfaces of both right and left lobes and so ...	1993	8376855
naturally occurring degrading events in axon terminals of the dentate gyrus and stratum lucidum in the spiny mouse (acomys cahirinus) during maturation, adulthood and aging.	the naturally occurring dynamics of presynaptic axon terminals were investigated in the dentate gyrus and stratum lucidum of the spiny mouse (acomys cahirinus) during maturation, adulthood and aging. a sensitive and selective silver-staining technique was applied to analyze neuronal lysosome accumulation (la), indicating synaptic degradation during development. la was quantified by counting silver grains in the inner third and outer two thirds of the molecular layer, granular layer, and the infr ...	1992	1286623
a relationship between circulating natural glucocorticoids and the mechanical responses of the heart in atricial and precocial rodents.	1. a comparison was made of the mechanical performance of heart muscle from mouse, an atricial mammal, with corticosterone as glucocorticoid and spiny mouse (acomys cahirinus), a precocial mammal, with cortisol as glucocorticoid. 2. force-frequency responses were negative in mouse and positive in spiny mouse. 3. during recovery, there was a gradual increase and an overshoot in the mouse, while in the spiny mouse there was an initial enhanced response, diminishing gradually with time. 4. high cal ...	1992	1361898
distance perception in the spiny mouse acomys cahirinus: vertical jumping.	acomys cahirinus, a precocial muroid, that has shown precise jumping in the natural habitat, did not jump from 25 cm in a laboratory situation. to investigate this further, a. cahirinus were observed jumping from platforms at two different heights, onto different sized checkered substrates and from a visual cliff. adult animals discriminated between platforms that were 6.4 cm and 25.4 cm above the substrate and between small and large checkered patterns on the floor. most adult animals and neona ...	1992	1454491
[a morphometric study of postnatal synaptogenesis in the neocortex of precocial and altricial rodents].	quantitative electronmicroscopic studies have been made on the development of synapses in two modally different areas of the brain (v-vi layers of the visual and auditory cortex) in the rat and mouse acomys cahirinus within first two weeks of their postnatal life. the density of synapses as well the relative amount of different types of synapses (symmetrical, asymmetrical, axo-spinal and synapses with large amounts of synaptic vesicles) were measured. it was shown that only in rats the developme ...	1992	1523896
behavioral response of altricial and precocial rodent fetuses to acute umbilical cord compression.	norway rat fetuses (rattus norvegicus) exhibit a stereotypic behavioral response when the umbilical cord is experimentally compressed with a vascular clamp. in this study, the development of the fetal behavioral response to cord compression was compared in altricial and precocial rodents, which differ markedly in neural and motor maturity at the time of birth. both altricial and precocial species showed some form of behavioral response to umbilical cord compression. fetuses of two altricial spec ...	1992	1586357
[the effect of early partial postnatal deafferentation of the visual cortex on synapse formation].	a quantitative analysis of the synaptic population of the upper layers of the visual cortex of mice acomys cahirinus has shown that the process of postnatal synaptogenesis proceeds during all the period of observations (1-13 days), the intensity of morphological differentiation of various types of synapses being higher during the first 5 days of life. partial deafferentation of the visual cortex (dissection of the corpus callosum) in 3-, 5- and 13-day-old acomyses results in changes of synapses ...	1992	1343253
maternal discrimination and the development of sex differences in exploratory behaviour in infant spiny mice (acomys cahirinus).	the present paper reports sex differences in exploratory behaviour by infant spiny mice, acomys cahirinus, that may, in part, be related to differences in maternal behaviour towards pups; like some other rodents, mother acomys differentiate behaviourally between male and female pups. in experiment 1 infant acomys were allowed to explore a novel arena. this experiment showed that even by day 3 (the day of birth = day 1) female acomys explored a novel environment more than males; they entered the ...	1991	1771244
drinking behavior in the spiny mouse (acomys cahirinus) following putative dipsogenic challenges.	male spiny mice (acomys cahirinus) were challenged with several putative dipsogenic stimulus conditions: hypertonic sodium chloride (nacl), 24-h water deprivation, d,l-isoproterenol hcl, angiotensin ii (aii) and polyethylene glycol (peg), or control conditions, in within-subjects designs. water intake and drinking pattern were monitored electronically in the home cage over a 2--6-h test period without food present, during the light portion of the l/d cycle. in addition, hematocrits were measured ...	1991	1871204
differences in beta-adrenergic regulation of cyclic amp formation in cerebral cortical slices of the rat and spiny mouse--acomys cahirinus.	in both the rat and acomys cahirinus the adrenergic cyclic amp generating system in the brain is dependent not only on beta-, but also on alpha-adrenoceptors. the relative role of alpha-adrenoceptors is much greater in the acomys cahirinus. this feature makes the acomys an interesting animal model for investigating the role of alpha-beta-adrenoceptor coupling in generation of cyclic amp and the mechanism of action of antidepressant treatment.	1990	1980732
effect of exogenous insulin on meal patterns and stomach emptying in the spiny mouse.	male adult spiny mice (acomys cahirinus) were acutely challenged with a single dose of regular insulin or saline vehicle sc; either food intake, meal frequency and meal duration, or stomach emptying were then measured. meal frequency, as well as amount eaten, was significantly higher over a 6-hr period following both 10 and 30 u/kg of insulin than following vehicle injection. meal duration remained essentially the same across all conditions. when 30 u/kg of insulin was administered either 15 min ...	1990	2201984
animals as reservoir hosts for leishmania in qualyobia governorate, egypt.	a total of 239 rodents were collected from el-khanka, shebin el-kanater, el-kanater, shoubra el khima, qualiob, tokh, benha and kafr-shokr and identified as mus musculus (30), rattus rattus (78), rattus norvegicus (35), arvicanthus niloticus (62) and acomys cahirinus (34). examination of these rodents showed the presence of cutaneous lesions in two r. rattus, three r. norvegicus and one a. cahirinus which showed no leishmania parasites neither by smear nor by culture. on examination of the liver ...	1990	2230335
the influence of maternal labels on dietary preferences of spiny mouse weanlings.	to assess the influence of conspecific chemical cues on the development of dietary preferences, spiny mouse (acomys cahirinus) weanling were tested for their responses to food items that were partially eaten (thus, presumably labeled) by various categories of conspecifics. consumption of a highly preferred novel food (fresh carrot) labeled by the pups' parents, or mother alone, was greater than that of a clean sample of the same food. the presence of labels emanating from the father or an alien ...	1990	2236255
an unusual pattern of copulatory behavior in a south american cricetid rodent: akodon molinae.	we describe the copulatory behavior and the morphology of the male genital tract of a member of a tribe (akodontini) for which no information on copulatory behavior has been available. copulation in akodon molinae is characterized by multiple intromissions with no intravaginal thrusting, a single ejaculation, and a brief lock with the deposit of a plug. this pattern is unusual because of the combination of locking with both multiple intromissions and plugs. the latter combination, and similar st ...	1990	2225764
husbandry and hematology of captive spiny mice (acomys cahirinus).		1989	2593647
development of sex differences in the response of spiny mouse pups to adult male odors.	using a three-choice preference test, olfactory-mediated investigatory activity in response to adult male urine odor was examined in a precocially active rodent, the spiny mouse (acomys cahirinus) aged between 3-26 days. temporally related sex differences were seen in the time spent in the presence of the odors of father's or unfamiliar adult male's urine, or distilled (control) water. neither male nor female pups discriminated between odors from the father and strange adult males. after the fir ...	1989	2629001
prenatal neurogenesis in the telencephalon of the precocial mouse acomys cahirinus.	[3h]thymidine autoradiography was employed to examine the times of formation of the major neuronal classes in the forebrain of the precocial mouse acomys cahirinus. dams received 3 thymidine injections over a 24 h period on either embryonic day 14, 18, 20, 22, 29 or 36. age-related changes in the distribution and number of heavily labeled cells were noted. acomys exhibited later onset and more protracted periods of cell generation than the phylogenetically related, altricial laboratory rat or mo ...	1989	2616023
trypanosoma acomys (wenyon, 1909): reproductive forms and course of parasitemia in the natural host acomys cahirinus (desmarest, 1819).	trypanosoma acomys (stercoraria, trypanosomatidae) was studied in the laboratory-bred spiny mouse acomys cahirinus. only trypomastigotes were found in peripheral blood, whereas the thymus of experimentally infected a. cahirinus showed amastigote syncytial reproductive forms whose nuclei of nuclei ranged from 2 to 128. these reproductive forms were detected 9-10 days after the i.p. injection of spiny mice with trypanosomes obtained from primary lung cultures. transitional trypomastigote-like form ...	1989	2755930
the development of olfactory preferences for artificial odors briefly experienced by the precocial spiny mouse young.	groups of pups, aged 2, 4, 6, 12, 16, and 18 days of the precocial murid rodent spiny mouse (acomys cahirinus), were each exposed for 1.5 h to one of the experimental odors, cinnamon or cumin, present in the surrounding environment. the odors were not contingent upon home-cage odors or any other reinforcers. this simple exposure produced a strong preference for the exposed odor in multichoice preference tests carried out 48 h after the exposure in pups from groups aged 2 through 16 days. older p ...	1989	2590153
reduced early and late phase insulin response to glucose in isolated spiny mouse (acomys cahirinus) islets: a defective link between glycolysis and adenylate cyclase.	the spiny mouse (acomys cahirinus) exhibits low insulin responsiveness to glucose with a nearly absent early phase release. the alternative fuel-secretagogue glyceraldehyde (10 mmol/l) produced a maximal early insulin response in rat islets but failed to affect early response in acomys; however, it potentiated the late insulin response in both species alike. glucagon (1.5 mumol/l) potentiated the early insulin response to intermediate (8.3 mmol/l) glucose in rat and acomys islets by two- and fou ...	1989	2477292
a comparative study of prenatal development in the olfactory bulb, neocortex and hippocampal region of the precocial mouse acomys cahirinus and rat.	unlike the remainder of the rodent subfamily muridae, acomys cahirinus (the 'spiny' mouse) is born in a precocial state after a long (39 day) gestation. in this paper, the development of the olfactory bulb, neocortex and hippocampal formation of acomys from prenatal days 14-34 was examined and the rate of maturation compared with that of its cousin, the laboratory rat (rattus norvegicus). at the earliest stages examined, acomys was approximately 2 days less mature than the same post-conception a ...	1989	2791267
electrophysiological effects of dopamine receptor stimulation in the hippocampus of acomys cahirinus.	the effect of dopamine receptor agonists on the spontaneous bioelectrical activity of ca1 layer neurons in the hippocampal slice preparation from the acomys and rat has been studied. the selective d1 receptor agonist skf 38393 diminished the neuronal firing rate while the selective d2 receptor agonist ly 171555 (quinpirole) evoked an excitatory reaction, however, a great proportion of hippocampal neurons remained unresponsive to skf 38393 and ly 171555. both dopamine and apomorphine elicited mai ...	1988	2908137
species differences in hepatic microsomal drug-metabolizing enzymes.	the activity of some metabolizing enzymes was assessed in the liver microsomes of acomys cahirinus, mice and rats. the enzymatic studies were followed by the determination of cerebral level of apomorphine (apo), imipramine (imi) and its metabolite desipramine (dmi) of animals treated with a single dose of apo or imi. it was found that the level of cytochrome p-450 and the activity of imi demethylase and glucuronyltransferase in the liver microsomes of rats was significantly higher than those in ...	1988	3222176
a comparative study of myelination in precocial and altricial murid rodents.	the development of myelin staining was compared in two closely related rodent species, the precocial acomys cahirinus and altricial rattus norvegicus. while the progression of myelin staining was similar in both species (motor tracts myelinated before sensory systems, which were followed by forebrain fiber systems), the timing of maturation differed considerably: (1) at the same postconception age (pc38) rattus was substantially more mature than acomys, suggesting a relatively earlier onset of m ...	1988	3219591
the acomys cahirinus (spiny mouse) as a new model for biological and neurobehavioural studies.	acomys cahirinus is a precocial murid and a comparison of its development with altricial species of the same family, such as the rat and mouse, may shed some light on the relationship between genetic and environmental factors in the development. the use of acomys in neurobehavioural studies and its comparison with mouse and rat may be particularly profitable. behavioural, differences particularly in the exploratory behaviour, are paralleled by differences in the brain anatomy. therefore acomys s ...	1988	3075753
effect of insulin and 2-deoxy-d-glucose on feeding and plasma glucose levels in the spiny mouse.	adult male spiny mice (acomys cahirinus) were challenged with 2-deoxy-d-glucose (2-dg) or regular insulin, and food intake or plasma glucose concentration was measured. mice did not increase their food intake over baseline levels following treatment with 2-dg (62.5-1000 mg/kg). in contrast, regular insulin injections (1-50 u/kg) stimulated a modest, but significant increase in feeding, which was apparent within 2 hr at a low dose of 1 u/kg. however, a marked hyper- and hypoglycemia (compared to ...	1988	3070582
a comparison of postnatal thermal physiology and energetics in an altricial (gerbillus perpallidus) and a precocial (acomys cahirinus) rodent species.	1. daily weight increase is polyphasic in gerbillus perpallidus whereas it follows a linear pattern in acomys cahirinus. 2. young a. cahirinus achieve full homeothermic capacities much earlier (less than or equal to 12 days old) than g. perpallidus (19-21 days old). 3. the differences in the development of the two species are reflected in the alterations of their metabolic rates. 4. in both species, age-dependent phases of development are obvious, beginning, however, much later in g. perpallidus ...	1988	2900101
a comparison of norepinephrine stimulated inositol phosphate accumulation in cerebral cortex of the acomys cahirinus, the laboratory mice and the rat.		1988	3222183
brain choline acetyltransferase and muscarinic receptor sites, brain and liver cholinesterases in precocial acomys cahirinus and altricial rat during post-natal development.	brain choline acetyltransferase, acetylcholinesterase with its molecular forms, and muscarinic receptor sites, as well as liver total cholinesterases were evaluated during the first postnatal month in pups of a precocial (acomys cahirinus) and altricial (rat) murid species. at birth the levels of brain cholinergic markers were higher in the acomys than in the rat, but in adulthood the differences were smaller or even reversed. the postnatal increase up in the markers to weaning was considerably ...	1988	3253718
precocity and plasticity: odor deprivation and brain development in the precocial mouse acomys cahirinus.	altering the early olfactory environment of animals can have dramatic consequences on the development of brain regions which subserve olfaction. the present study indicates that early odor deprivation has a more severe effect on a species which is born relatively mature than it does on related species which are not. the results call into question prevailing notions about the developmental continuity between animals born in divergent ontogenetic states.	1988	3362353
effect of electrical stimulation of the vagus nerve on insulinemia and glycemia in acomys cahirinus mice.	to investigate the parasympathetic regulation of the endocrine pancreas in spiny mice (acomys cahirinus), unilateral electrical stimulations of the left cervical vagus nerve were performed in these animals and their controls, the albino mice. plasma insulin and glucose levels were measured before and after the stimulation. the stimulation parameters were: 2-2.5 v, 14 hz, 1 msec for the albino mice and 3 v, 14 hz, 1 msec or 15-20 v, 20 hz, 1 msec for the spiny mice. already 2 min after the start ...	1988	3293988
spiny mouse's (acomys cahirinus) use of its distance senses in prey localization.	this study examined the relative importance that olfaction, audition and vision played in the spiny mouse's localization of insect prey. these three senses were blocked singly or in various combinations so that a mouse was tested under 8 different situations with a tethered live cricket and four with a dead cricket. the mice did not rely on one particular sense more than the others, but in certain situations olfaction and audition proved more important than vision in the localization of a live c ...	1988	24896404
[the features of the hippocampal structure as a neuroanatomical basis for differences in behavior].	neuromorphological and behavioural studies have been made on several strains of mice (c57b1, dba/2, sec) and on the spiny mouse acomys cahirinus. it was shown that animals with different genotypes differ by the size of fascia dentata and by the extension of the pyramidal layer in ca3 field of the hippocamp. animals with a higher learning capacity exhibited smaller layer of granular cells in the fascia dentata, which may be due to a lower density of neurones in this region. terminals of the mossy ...	1987	3434039
a comparison of locomotor responses to some psychotropic drugs and cerebral receptors in the acomys cahirinus and the laboratory mouse.	comparative studies of the laboratory mouse and acomys cahirinus have shown differences in their motor activity patterns and motor responses to morphine, apomorphine and clonidine. the two species also differed in respect of the density of cerebral alpha 2-adrenergic receptors, but no significant differences between other types of receptors (alpha 1-adrenergic, beta-adrenergic, opiate mu and delta, and spiroperidol binding sites) were found. it is suggested that the high excitability of the acom ...	1987	2830608
effects of odor familiarity on the development of systematic exploration in the spiny mouse, acomys cahirinus.	developmental changes in patterns of exploration by infant spiny mice, acomys cahirinus are described. these were investigated using an unbaited radial maze and under three odor conditions; that is, animals were tested in the presence of either familiar (own) odors, unfamiliar conspecific odors, or no odors (washed floor). two hypotheses were tested. the first was based on the results of a pilot study, and was that adult animals would explore the radial maze in a systematic and predictable fashi ...	1987	3691969
species differences in polysaccharide and sugar taste preferences.	this study compared the polysaccharide and sugar taste preferences of humans and four rodent species (laboratory rats, rattus norvegicus; golden syrian hamsters, mesocricetus auratus; mongolian gerbils, meriones unguiculatus; egyptian spiny mice, acomys cahirinus). in experiment 1 human subjects rated the pleasantness, sweetness, and flavor intensity of polysaccharide (polycose), sucrose, and maltose solutions at concentrations of 0.0125 m to 0.4 m, and 1% to 32% concentrations. at the higher mo ...	1987	3614791
opioid modulation of ingestive behaviors in the spiny mouse (acomys cahirinus).	feeding and drinking behavior were studied in deprived or sated spiny mice (acomys cahirinus) at various time intervals following peripheral administration of naloxone hydrochloride and butorphanol tartrate. naloxone attenuated both food and water intake, but not latency to respond, indicating existence of functional opioid-sensitive feeding and drinking systems in this species. butorphanol tartrate, a mixed opioid agonist/antagonist produced a dose-related enhancement or suppression of feeding, ...	1987	3613855
[comparative study of the brain of developed and underdeveloped neonatal rodents of the muridae family].	morphological studies have been made of the neocortical and archicortical structures in the spiny mouse acomys cahirinus, the only maturely born species from the family muridae. the data obtained reveal highly developed hippocampus as compared to the neocortex in this mouse, in contrast to relationships found in other mice and rats.	1987	3564772
patterns of exploratory behavior in the spiny mouse, acomys cahirinus.	the present paper reports an investigation of patterns of exploratory behavior shown by laboratory-bred spiny mice (acomys cahirinus) when given access to a large, novel arena. the aim was to test hypotheses suggested by our previous work with this species. previous experiments in which the exploratory behavior of acomys was compared with that of mus had suggested that each species had a characteristic pattern of emergence and exploration. the present experiment addressed the question of whether ...	1986	3954718
postnatal maturation of brain cholinergic systems in the precocial murid acomys cahirinus: comparison with the altricial rat.	the spiny mouse (acomys cahirinus) is the only precocial murid species. it has some neuroanatomical peculiarities such as a relatively thin cerebral cortex and a large hippocampus. the levels of choline acetyltransferase, membrane-bound acetylcholinesterase and muscarinic receptor sites (measured as [3h]quinuclidynil benzilate binding) were assessed in the whole brain on days 1, 7, 14, 21, 28 and 80 (adult), and compared with those of wistar rats of the corresponding ages. at birth choline acety ...	1986	3455597
hormones in perinatal rat and spiny mouse: relation to altricial and precocial timing of birth.	rat (rattus norvegicus) and spiny mouse (acomys cahirinus) are closely related murine species that, due to their altricial (rat) and precocial (spiny mouse) modes of development, differ in the developmental timing of birth. a comparison between the developmental profiles of plasma glucagon, insulin, thyroxine, triiodothyronine, and glucocorticosteroid hormone was carried out to elucidate the question to what extent these hormonal profiles were related to the timing of birth. although corticoster ...	1986	3524260
physical and behavioral sequelae of low birthweight in spiny mice (acomys cahirinus).	physical and behavioral sequelae of low birthweight (lbw) were investigated in spiny mice (acomys cahirinus). when raised by their biological mother, pups whose day-2 weights were 1 sd or more below the population mean remained smaller through the first 30 days postpartum than pups born within normal (n) weight ranges. lbw pups fostered onto mothers who gave birth to n pups gained weight more rapidly than lbw pups remaining with their own mother. similarly, n pups fostered onto mothers of lbw pu ...	1986	3758489
a comparative study of mossy fiber distribution in the brain of the precocial acomys cahirinus and of the altricial rattus norvegicus: neuroanatomical bases and behavioral correlates.	acomys cahirinus, the spiny mouse, is the only precocial murid. given the relatively advanced state of neural maturation at birth, this species is therefore of interest for comparative studies of brain and behavioural development. previous work on this species has indicated that (i) hippocampal thickness (relative to body weight) is greater in adult acomys than in rats and mice; (ii) the hippocampus appears laminated at birth, unlike that of related altricial species; (iii) the degree of olfacto ...	1985	2419270
perinatal development of the small intestine and pancreas in rat and spiny mouse. its relation to altricial and precocial timing of birth.	rat (rattus norvegicus) and spiny mouse (acomys cahirinus) are closely related species that mainly differ in the developmental timing of birth. a comparison between the developmental profiles of some characteristic enzymes of the small intestine (lactase and sucrase) and of the pancreas (amylase) of both species was carried out to elucidate the question to what extent these enzymic profiles and hence the maturation of these organs was related to the process of birth. it was found that these orga ...	1985	3921064
correction of diabetic pattern of insulin release from islets of the spiny mouse (acomys cahirinus) by glucose priming in vitro.	insulin release kinetics were studied in perifused islets of langerhans, isolated from mildly hyperglycaemic and from normoglycaemic spiny mice (acomys cahirinus), a rodent predisposed to develop spontaneously non-ketotic diabetes. in both groups, insulin response to glucose (16.7 mmol/l) was delayed in comparison with that of rat islets, the release kinetics being analogous to that of human type 2 (non-insulin-dependent) diabetes. thirty min priming of the isolated acomys islets with glucose (1 ...	1985	3894135
exploratory behavior of two species of murid rodents, acomys cahirinus and mus musculus: a comparative study.	the exploratory behavior of two species of murid rodents, acomys cahirinus and mus musculus, was compared in four experiments: in the first, the responses of the two species to a novel arena were studied. mus was found to take longer to enter the arena, and to spend more time in the relatively familiar or safer start box, than was acomys. the results suggest that acomys may persevere longer in exploring particular areas, whereas mus appear to explore in the open arena by using frequent shifts of ...	1985	4004686
a stereological study of neocortical maturation in the precocial mouse, acomys cahirinus.	the development of neocortical area 17 of acomys cahirinus was studied by quantifying changes in the numerical density of neurons and glia, and by examinations of subjects treated on the day of birth with tritiated thymidine. unlike most laboratory species, acomys is born in a relatively advanced state, with open and functional ears and eyes and coordinated locomotor abilities. rapid neocortical growth occurred during the first 60 postnatal days and was accompanied by a 65% decrease in neuronal ...	1985	3995352
perinatal development of the liver in rat and spiny mouse. its relation to altricial and precocial timing of birth.	rat (rattus norvegicus) and spiny mouse (acomys cahirinus) are closely related murinoid species that mainly differ in the developmental timing of birth. a comparison between the developmental profiles of some characteristic enzymes of the liver of both species was carried out to elucidate the question to what extent are these enzymic profiles and hence the maturation of the liver related to the timing of birth? it was found that these organotypic enzymes first become detectable at the same devel ...	1985	3967668
response of hepatic fructokinase to long-term sucrose diets and diabetes in spiny mice, albino mice and rats.	the activity of hepatic fructokinase increased about 2-fold in desert-derived spiny mice (acomys cahirinus) and laboratory bred albino mice and rats, maintained on a 50% sucrose diet for 3 months. the role of fructose as the specific inducer was apparent, as 25% fructose diet produced activity increases similar to those of sucrose in contrast to 25% glucose diet. the activity of hexokinase was not affected by the sucrose diet, that of glucokinase rose marginally but those of pyruvate kinase and ...	1984	6088170
paternal behavior in the spiny mouse (acomys cahirinus).	the responsiveness of adult male spiny mice (acomys cahirinus) to both their own and alien precocial young was investigated. paternal behavior was manifested primarily by the males huddling with their offspring and the coordination of pup attendance between adult males and females. with less than 2 days exposure to their own neonates, males were found to discriminate between their own and alien young. experience plays an important role in the development of paternal behavior in spiny mice. males ...	1984	6487216
perinatal development of the lung in rat and spiny mouse: its relation to altricial and precocial timing of birth.	rat and spiny mouse (acomys cahirinus) are closely related murinoid species that represent altricial (rat) and precocial (spiny mouse) modes of development. the late intrauterine developmental stages of the spiny mouse therefore seem comparable to the early extrauterine developmental stages of the rat. to elucidate the question to what extent the development of the lung is related to the developmental timing of birth, we have studied some enzymes involved in the de novo synthesis of phosphatidyl ...	1984	6326867
hippocampal maturation in the precocial murid rodent acomys cahirinus.	growth rates in the dentate gyrus and hippocampus proper of the precocial murid acomys cahirinus were examined by measuring age-related changes in laminar volume in 0-, 10-, 20-, and 60-day postpartum animals. a biphasic course of maturation was observed in both structures, with rapid expansion occurring in the first 10 postnatal days and more gradual growth thereafter. this pattern of growth resembles those reported for newborn altricial murids such as the laboratory mouse and rat. however, due ...	1984	6713169
brain acetylcholinesterase and its molecular forms in a precocial murid, acomys cahirinus, and rat during post-natal development.	brain acetylcholinesterase (ache) and its molecular forms of a precocial murid, acomys cahirinus, characterized by a large hippocampus, were measured during post-natal development and compared with rat. the activity of soluble ache in acomys increased slightly up to 4 weeks after birth. the total ache activity increased somewhat more but, in rats, this increase was still greater. three main molecular forms of ache were separated by 7.5% polyacrylamide gel electrophoresis. their close similarity ...	1984	6720191
sucrose diet induced enzymatic and hormonal responses affecting carbohydrate, lipid and energy metabolism in two species differing in insulin availability: spiny and ob/ob mice.	the low-insulin responding spiny mice (acomys cahirinus), maintained on a 50% sucrose diet vs isocaloric regular diet, responded with an impressive increase in the activity of hepatic enzymes of glycolysis and lipogenesis and in hyperlipidemia. there was no hyperinsulinemia or hyperglycemia and spiny mice did not gain weight on sucrose due to loss of adipose tissue. serum t3 levels rose 1.8 fold and the activity of the hepatic mitochondrial fad-glycerol-3-phosphate oxidase became induced 2.6 fol ...	1984	6370752
olfactory bulb maturation in acomys cahirinus: is neural growth similar in precocial and altricial murids?	olfactory bulb maturation was assessed in the precocial murid acomys cahirinus by quantifying developmental changes in laminar volume and glomerular and mitral cell size. at the time of birth (38 days postconception), the acomys bulb is in a developmental state similar to that of altricial murids of the same gestational age. rapid growth occurs in acomys during the first 10 postnatal days with more gradual changes occurring thereafter. altricial murids also exhibit accelerated bulb development i ...	1983	6871728
enzymatic and metabolic responses to affluent diet of two diabetes-prone species of spiny mice: acomys cahirinus and acomys russatus.	the adaptive responses to sucrose and fat diets were investigated in two species of spiny mice, acomys russatus and acomys cahirinus, in relation to their propensity to develop diabetic-like symptoms. a russatus gained weight pronouncedly, both on regular and fat-rich seed diet, did not exhibit hyperglycemia or hyperlipidemia but had highly increased hepatic triglyceride content in association with high levels of circulating free fatty acids and incidence of ketonuria in 10 of 41 animals. on the ...	1983	6360745
chromosomal phylogeny of muridae: a study of 10 genera.	the karyotypes of 10 different species of the family muridae (acomys airensis, arvicanthis niloticus, hylomyscus stella, malacomys longipes, mastomys huberti, myomys daltoni, mus musculus, rattus norvegicus, thamnomys gazellae, and uranomys ruddi) are compared by different banding techniques. from a reconstruction of the presumed ancestral karyotype of the muridae the sequence of the various rearrangements leading to the present karyotypes is proposed in order to determine their phylogenetic rel ...	1983	6617265
archicortex and neocortex in the precocial murid acomys cahirinus. a comparison with two altricial species: mus musculus and rattus norvegicus.	a morphological analysis of some structures of the archicortex and neocortex was performed in the acomys cahirinus (spiny mouse), the only precocial murid. the data obtained indicate that the spiny mouse brain is an interesting case of a largely developed hippocampus with respect to the neocortex when compared to the brains of the mouse and rat. the precocious pups of the spiny mouse present the peculiarity among murids of an early olfactory imprinting.	1983	6668122
intermediary metabolism during the development of obesity and diabetes in the desert rodent acomys cahirinus.	the spiny mouse acomys cahirinus, which exhibits beta-cell hyperplasia but low insulin secretion in captivity responded with hyperlipidemia without obesity or diabetes on a sucrose diet and became obese, and glucose-intolerant on a diet of fat-rich seeds. a three-month sucrose diet induced a marked rise in the activity of regulatory enzymes of glycolysis and lipogenesis in the liver but not in adipose tissue. there was also increased energy waste on this diet evident from a three-fold rise in th ...	1982	7118367
the metabolism of cyclic amp and glucose in isolated islets from acomys cahirinus.	glucose-induced cyclic (3h) amp accumulation, insulin secretory responses and the metabolism of glucose were studied in pancreatic islets from acomys cahirinus. 27.7 mmol/l of glucose stimulated neither islet cyclic (3h) amp accumulation nor insulin release during the first 5 min of incubation. stimulation by glucose of cyclic (3h) amp was observed after 15 min of incubation and insulin release was markedly stimulated between 15 and 30 min. the utilization of glucose, measured as the production ...	1982	216600
[pyroantimonate-bound cations in the beta-cells of spiny mice pancreas (acomys cahirinus)].		1981	7032701
the response of the egyptian spiny mouse (acomys cahirinus) and two other species of commensal rodents to anticoagulant rodenticides.	the response of acomys cahirinus to three anticoagulant rodenticides was investigated in the laboratory. in contrast to the other commensal rodents rattus rattus and r. norvegicus, this species appears to be naturally very resistant to warfarin, difenacoum and brodifacoum. it is considered unlikely that anticoagulant poisons would be effective in the field for the control of a. cahirinus.	1981	7240734
comparison of insulin secretion by the isolated perfused pancreas and perifused islets of the spiny mouse (acomys cahirinus).	the dynamics of glucose-stimulated insulin release were studied in the perfused pancreas and in isolated perifused islets of spiny mice. the pattern of insulin release induced by an increase of the glucose concentration from 2.8 mm to 16.7 mm was different in the two preparations. in the perfused pancreas there was an early insulin release contrasting with an absence of the early response in isolated islets. the later insulin release response (5 min to 30 min) was present and similar in both pre ...	1981	7020305
the oestrous cycle of the spiny mouse (acomys cahirinus).	the oestrous cycle of the spiny mouse (acomys cahirinus), as determined by vaginal smears, is 11.1 +/- 1.9 (s.d.) days (n = 110). the vaginal smears show cell patterns similar to those seen in the rat, but secretion of mucus is greater than in the rat. the average age at vaginal opening is 45 +/- 2.77 (s.e.m.) days, but the first litter (sired by litter mates) did not occur until 103 +/- 4.04 (s.e.m.) days. the decidual response to uterine trauma indicates tha there is an active luteal phase. th ...	1981	7193735