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trends in prevalence of allergic rhinitis and correlation with pollen counts in switzerland.in recent decades, a large number of epidemiological studies investigating the change of prevalence of hay fever showed an increase in the occurrence of this disease. however, other studies carried out in the 1990s yielded contradictory results. many environmental factors have been hypothesized to contribute to the increasing hay fever rate, including both indoor and ambient air pollution, reduced exposure to microbial stimulation and changes in diets. however, the observed increase has not conv ...200818751737
combined hplc-cuprac (cupric ion reducing antioxidant capacity) assay of parsley, celery leaves, and nettle.this study aims to identify the essential antioxidant compounds present in parsley (petroselinum sativum) and celery (apium graveolens) leaves belonging to the umbelliferae (apiaceae) family, and in stinging nettle (urtica dioica) belonging to urticaceae family, to measure the total antioxidant capacity (tac) of these compounds with cuprac (cupric ion reducing antioxidant capacity) and abts spectrophotometric methods, and to correlate the tac with high performance liquid chromatography (hplc) fi ...200818804638
safety concerns for the potential use of cyanovirin-n as a microbicidal anti-hiv agent.based on its antiviral activity profile, cyanovirin-n (cv-n) holds great potential for anti-hiv microbicidal application. however, limited data are available on the possible side-effects of this lectin. a detailed investigation was carried out to obtain better insights in the cytotoxic, inflammatory and (anti)-proliferative properties of cv-n in comparison with several other plant-derived lectins. cv-n affected the cell morphology of pbmcs and enhanced the expression of the cellular activation m ...200818598778
an experimental study of nettle feeding in captive gorillas.mountain gorillas (gorilla beringei beringei) in karisoke, rwanda, feed on the stinging nettle laportea alatipes by means of elaborate processing skills. byrne [e.g. philosophical transactions of the royal society of london, series b, biological sciences 358:529-536, 2003] has claimed that individuals acquire these skills by means of the so-called program-level imitation, in which the overall sequence of problem-solving steps (not the precise actions) is reproduced. in this study we present west ...200818330896
clinical and histopathological evaluation of mdp/collagen induced arthritis rat model (mcia) after treatment with urtica dioica, plantago major and hypericum perforatum l herbal mixture.this study was done to assess the effects of urtica dioica, plantago major and hypericum perforatum l herbal mixture in the mcia rat model. in addition, a new pathological and clinical arthritis lesion assessment was developed. sprague-dawley (sd) rats were immunized with bovine type ii collagen and muramyl dipeptide (mdp). commercial herbal extracts were administered daily to the rats after the immunization for the course of experiment (90 days). rats were boosted with a second collagen-mdp emu ...200818421172
simian immunodeficiency virus is susceptible to inhibition by carbohydrate-binding agents in a manner similar to that of hiv: implications for further preclinical drug development.carbohydrate-binding agents (cbas), such as the plant lectins hippeastrum hybrid agglutinin (hha) and urtica dioica agglutinin (uda), but also the nonpeptidic antibiotic pradimicin a (prm-a), inhibit entry of hiv into its target cells by binding to the glycans of gp120. given the high sequence identity and similarity between the envelope gp120 glycoproteins of hiv and simian immunodeficiency virus (siv), the inhibitory activity of a variety of cbas were evaluated against hiv-1, hiv-2, and siv. t ...200818474667
factors related to complementary/alternative medicine use among cancer patients in central anatolia.we aimed to evaluate the prevalence of and factors related to the use of complementary/alternative medicine among cancer patients undergoing or following conventional treatment at the erciyes university oncology hospital in central anatolia.200819267101
glycan deletions in the hiv-1 gp120 v1/v2 domain compromise viral infectivity, sensitize the mutant virus strains to carbohydrate-binding agents and represent a specific target for therapeutic intervention.carbohydrate-binding agents (cbas), such as the mannose-specific hippeastrum hybrid agglutinin (hha) and the glcnac-specific urtica dioica agglutinin (uda), frequently select for glycan deletions in all different domains of hiv-1 gp120, except in the v1/v2 domain. to reveal the underlying mechanisms, a broad variety of 31 different virus strains containing one or several n-glycan deletions in v1/v2 of the gp120 of the x4-tropic hiv-1(nl4.3) were constructed by chimeric virus technology. no co-re ...200818930512
biological screening of some turkish medicinal plant extracts for antimicrobial and toxicity activities.screening of antibacterial activity and toxicity of 22 aqueous plant extracts from 17 turkish plants was conducted. antibacterial activity was performed with six bacteria including escherichia coli, pseudomonas aeruginosa, klebsiella pneumoniae, streptococcus pyogenes, staphylococcus aureus and staphylococcus epidermidis. extracts of tussilago farfara leaves, helichyrsum plicatum flowers, solanum dulcamara aerial parts and urtica dioica leaves gave the best inhibitory activity against s. pyogene ...200818075897
inhibition of cell-to-cell transmission of human t-cell lymphotropic virus type 1 in vitro by carbohydrate-binding agents.peripheral blood mononuclear cells (pbmcs) from healthy individuals can be infected by human t-lymphotropic virus type 1 (htlv-1) upon cocultivation of the pbmcs with irradiated htlv-1-transformed human mt-2 cells. this model system closely mimics htlv-1 transmission through cell-to-cell contact. carbohydrate-binding agents (cbas) such as the alpha(1,3)/alpha(1,6)mannose-specific hippeastrum hybrid agglutinin and the glcnac-specific urtica dioica agglutinin, and also the small, nonpeptidic alpha ...200818505856
toxicological assessment of p-9801091 plant mixture extract after chronic administration in cba/hzg mice--a biochemical and histological study.acute, subchronic and chronic effects of the p-9801091 plant mixture extract at a dose of 20 mg/kg body mass were assessed in serum of healthy cba/hzg mice at 24 hours, 7 days, 3 months and 6 months of treatment (experimental group), and compared with the values obtained in the control group of untreated healthy cba/hzg mice. the p-9801091 plant mixture extract is an antihyperglycemic preparation containing myrtilli folium (vaccinium myrtillus l.), taraxaci radix (taraxacum officinale web.), cic ...200818756913
the granule cell density of the dentate gyrus following administration of urtica dioica extract to young diabetic rats.urtica dioica l. stinging nettle has long been known worldwide as a medicinal plant. to study the benefits of the nettle in diabetic encephalopathy, the granule cell density of the dentate gyrus of diabetic rats was studied following administration of urtica dioica extract. a total of 24 male albino wistar rats were allocated equally to normal, diabetic, preventive and treatment groups. hyperglycaemia was induced by streptozotocin (80 mg/kg) in the animals of the diabetic and treatment groups. o ...200818828102
maintaining a physiological blood glucose level with 'glucolevel', a combination of four anti-diabetes plants used in the traditional arab herbal medicine.safety and anti-diabetic effects of glucolevel, a mixture of dry extract of leaves of the juglans regia l, olea europea l, urtica dioica l and atriplex halimus l were evaluated using in vivo and in vitro test systems. no sign of toxic effects (using ldh assay) were seen in cultured human fibroblasts treated with increasing concentrations of glucolevel. similar observations were seen in vivo studies using rats (ld50: 25 g/kg). anti-diabetic effects were evidenced by the augmentation of glucose up ...200818955212
the use of complementary therapies in cancer patients: a questionnaire-based descriptive survey from southeastern turkey.a study was designed to measure the frequency of complementary therapy (ct) usage in cancer patients in southeastern turkey. the demographic characteristics associated with the use of ct are sought in patients undergoing or following conventional treatment.200819060593
in vitro nematicidal effects of medicinal plants from the sierra de huautla, biosphere reserve, morelos, mexico against haemonchus contortus infective larvae.twenty extracts from plants from sierra de huautla biosphere reserve, morelos, mexico were evaluated against haemonchus contortus infective larvae in an in vitro assay. the plant species evaluated were bursera copallifera, b. grandifolia, lippia graveolens, passiflora mexicana, prosopis laevigata, randia echinocarpa and urtica dioica. the plants were separated into their parts and macerated with different solvents (n-hexane, acetone, ethanol and methanol). an in vitro assay was used to evaluate ...200818053304
risks and benefits of commonly used herbal medicines in mexico.in mexico, local empirical knowledge about medicinal properties of plants is the basis for their use as home remedies. it is generally accepted by many people in mexico and elsewhere in the world that beneficial medicinal effects can be obtained by ingesting plant products. in this review, we focus on the potential pharmacologic bases for herbal plant efficacy, but we also raise concerns about the safety of these agents, which have not been fully assessed. although numerous randomized clinical t ...200818037151
the protective activity of urtica dioica leaves on blood glucose concentration and beta-cells in streptozotocin-diabetic rats.this study was done to determine the protective activity of the hydroalcholic extract of urtica dioica leaves on hyperglycemia and beta-cells in hyperglycemic rats. thirty wistar rats were allocated in groups of normal, diabetic and treatment. hyperglycemia in rats induced by 80 mg kg(-1) streptozotocin. in treatment group, animals received hydroalcholic extract of urtica dioica 100 mg kg(-1) day(-1) for five days, intraperitoneally and then hyperglycemia induced by streptozotocin. the blood glu ...200719069917
complementary/alternative medicine use in a pediatric oncology unit in turkey.important in the cancer therapy is the increasingly use of complementary/alternative medicine (cam). the current study aims to establish the extent of use, the types of therapies employed, factors influencing, the reasons for choosing and the cost of cam used in pediatric cancer patients in our clinic in ankara, turkey.200716900485
the carbohydrate-binding plant lectins and the non-peptidic antibiotic pradimicin a target the glycans of the coronavirus envelope glycoproteins.many enveloped viruses carry carbohydrate-containing proteins on their surface. these glycoproteins are key to the infection process as they are mediators of the receptor binding and membrane fusion of the virion with the host cell. therefore, they are attractive therapeutic targets for the development of novel antiviral therapies. recently, carbohydrate-binding agents (cba) were shown to possess antiviral activity towards coronaviruses. the current study further elucidates the inhibitory mode o ...200717704516
gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (urtica dioica).nettle (urtica dioica) is commonly sold as a herbal tea in turkey. we report a case of gynaecomastia in a man (in which the only aetiologic factor identified was nettle tea consumption) and a case of galactorrhoea in a woman (in which the only aetiologic factor identified was also nettle tea ingestion).200718264183
effect of urtica dioica on morphometric indices of kidney in streptozotocin diabetic rats--a stereological study.the aim of the present study was to investigate the effect of urtica dioica on morphometric indices of kidney in diabetic rats. thirty male adult albino wistar rats of 125-175 g divided into control, diabetic and urtica dioica treatment groups. in treatment group, diabetic rats received 100 mg kg(-1) daily hydroalcoholic extract of u. dioica intraperitoneally for 4 weeks. after the animals had been sacrified, the kidneys were removed and fixed by formaldehyde, cut horizontally into 1 mm slices a ...200719090245
complementary and alternative medicine use in pediatric oncology patients in eastern turkey.the use of complementary and alternative medicines (cam) among children with cancer is becoming increasingly popular. therefore, it is important to gain insight into the prevalence and factors related to the use of cam. this study presents findings from a study of parents of 88 children with cancer who were receiving or had received conventional therapy for treatment of childhood cancer at a pediatric oncology unit in eastern turkey. the findings indicated that 48.9% of the respondents reported ...200717235218
wild vascular plants gathered for consumption in the polish countryside: a review.this paper is an ethnobotanical review of wild edible plants gathered for consumption from the end of the 18th century to the present day, within the present borders of poland.200717433114
medicinal plants used in kirklareli province (turkey).in this paper, 126 traditional medicinal plants from kirklareli province in turkey have been reported. one hundred and twenty six plant species belonging to 54 families and among them 100 species were wild and 26 species were cultivated plants. most used families were rosaceae, labiatae, compositae and the most used plants were cotinus coggyria, sambucus ebulus, achillea millefolium subsp. pannonica, hypericum perforatum, matricaria chamomilla var. recutita, melissa officinalis subsp. officinali ...200717257791
an ethnobotanical study on the usage of wild medicinal herbs from kopaonik mountain (central serbia).an ethnobotanical survey was carried out on the territory of the highest mountain in central serbia, kopaonik, which is characterized by great plant diversity. in total, 83 wild species from 41 families and 96 preparations for use in human therapy were recorded. among those wild plants which are most commonly used for medicinal purposes, hypericum perforatum l., urtica dioica l., achillea millefolium l., matricaria chamomilla l., sambucus nigra l., and thymus serpyllum l. were particularly highl ...200717145148
the importance of a taste. a comparative study on wild food plant consumption in twenty-one local communities in italy.a comparative food ethnobotanical study was carried out in twenty-one local communities in italy, fourteen of which were located in northern italy, one in central italy, one in sardinia, and four in southern italy. 549 informants were asked to name and describe food uses of wild botanicals they currently gather and consume. data showed that gathering, processing and consuming wild food plants are still important activities in all the selected areas. a few botanicals were quoted and cited in mult ...200717480214
elevation protective role of camellia sinensis and urtica dioica infusion against trichloroacetic acid-exposed in rats.this study was designed to investigate the protective effects of two traditionally used turkish medicinal plants, camellia sinensis (cs) and urtica dioica l. (ud), beverages used against chemical carcinogen trichloroacetic acid (tca)-exposure in rats. the preventive potential of the plant infusions was evaluated by measuring the level of serum marker enzymes, aspartate aminotransferase (ast), alanine aminotransferase (alt), creatine phosphokinase (cpk), acid phosphatase (acp), alkaline phosphata ...200717622976
ethnoveterinary medicines used for ruminants in british columbia, canada.the use of medicinal plants is an option for livestock farmers who are not allowed to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock.200717324258
carbohydrate-binding agents efficiently prevent dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (dc-sign)-directed hiv-1 transmission to t lymphocytes.exposure of hiv-1 to dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (dc-sign)-expressing b-lymphoblast raji cells (raji/dc-sign) but not to wild-type raji/0 cells results in the capture of hiv-1 particles to the cells as measured by the quantification of cell-associated p24 antigen. cocultivation of hiv-1-captured raji/dc-sign cells with uninfected cd4+ t lymphocyte c8166 cells results in abundant formation of syncytia within 36 h after cocultivation. short preexp ...200717056872
antiviral activity of carbohydrate-binding agents against nidovirales in cell culture.coronaviruses are important human and animal pathogens, the relevance of which increased due to the emergence of new human coronaviruses like sars-cov, hku1 and nl63. together with toroviruses, arteriviruses, and roniviruses the coronaviruses belong to the order nidovirales. so far antivirals are hardly available to combat infections with viruses of this order. therefore, various antiviral strategies to counter nidoviral infections are under evaluation. lectins, which bind to n-linked oligosacch ...200717560666
the dispersal of vascular plants in a forest mosaic by a guild of mammalian herbivores.endozochorous seed dispersal by herbivores can affect plant spatial dynamics and macroecological patterns. we have investigated the number and species composition of viable seeds deposited in faeces of a full guild of macroherbivores (four deer and two lagomorph species) in a forest in eastern britain. one hundred and one plant species germinated from faecal pellet material, 85 of which were among the 247 vascular plant species recorded in the forest. however, three species - chenopodium album, ...200717661087
antioxidant capacity changes and phenolic profile of echinacea purpurea, nettle (urtica dioica l.), and dandelion (taraxacum officinale) after application of polyamine and phenolic biosynthesis regulators.the changes of the antioxidant (aoa) and antiradical activities (ara) and the total contents of phenolics, anthocyanins, flavonols, and hydroxybenzoic acid in roots and different aerial sections of echinacea purpurea, nettle, and dandelion, after treatment with ornithine decarboxylase inhibitor, a polyamine inhibitor (o-phosphoethanolamine, kf), and a phenol biosynthesis stimulator (carboxymethyl chitin glucan, cchg) were analyzed spectrophotometrically; hydroxycinnamic acids content was analyze ...200717579437
impact of field margin vegetation and herbage removal on ingrowing and anemochorous weeds.this research studies the effect of different ways to establish and to maintain unfertilised field margins on the development of potential weed plants and seed dispersal into adjacent crops. plant communities in field margins either developed spontaneously or were sown with different seed mixtures of grasses and forbs. margins were mown twice a year and the cuttings were either removed or not. three years after establishment, the importance of important weeds elymus repens, cirsium arvense and u ...200617390818
inter- and intra-guild interactions related to aphids in nettle (urtica dioica l.) strips closed to field crops.a field experiment designed to assess the biodiversity related to nettle strips closed to crops, and more particularly the aphid and related beneficial populations, was established in experimental farm located in gembloux (belgium). margin strips of nettle (urtica dioica) closed to wheat (triticum aestivum), green pea (pisum sativum) and rape (brassicae napus) fields were investigated. the diversity, abundance of aphids and related predators were analysed according to the plant crop species and ...200617385508
the use of medicinal herbs by diabetic jordanian patients.diabetes mellitus is the most common metabolic disorder worldwide. to date, there have been no reports on the frequency of use of herb medicines in the managements of diabetes mellitus in jordan. this cross-sectional study was conducted by interviewing 310 diabetic patients visiting two medical centers in jordan: jordan university of science & technology medical center and sarih medical center between december 2003 and august 2004. it is found that 31% of interviewed patients have used herbal pr ...200617182483
allergenic proteins in urtica dioica, a member of the urticaceae allergenic family.allergy to the pollen of flowering plant species significantly affects the health of people in many parts of the world. pollens of related genera usually share common antigens and are often, but not always, cross-reactive. several studies have shown that parietaria pollen is one of the most common causes of pollinosis in the mediterranean area, whereas urtica has no allergenic significance.200617042140
inhibition of rat platelet aggregation by urtica dioica leaves extracts.platelet hyperactivity plays an important role in arterial thrombosis and atherosclerosis. the present study was undertaken to investigate the effects of different extracts of urtica dioica leaves on platelet aggregation. rat platelets were prepared and incubated in vitro with different concentrations of the tested extracts and aggregation was induced by different agonists including thrombin (0.5 u/ml), adp (10 microm), epinephrine (100 microm) and collagen (5 mg/ml). the crude aqueous extract i ...200616619332
effect of urtica dioica on bacterial translocation in mechanic icter model. 200616680282
effect of urtica dioica extract intake upon blood lipid profile in the rats.aqueous (150 mg/kg/day) and to a lesser extent petroleum ether (20 mg/kg/day) extract of urtica dioica given for 30 days to rats fed with normal or high-fat diet, improved the blood lipid profile. significant decreases in total cholesterol, ldl cholesterol, ldl/hdl cholesterol ratio and plasma total apo b were observed. assessment of got, gpt and ldh activities showed that no liver damage has occurred during the study period.200616540261
spatial distribution of aglais urticae (l.) and its host plant urtica dioica (l.) in an agricultural landscape: implications for bt maize risk assessment and post-market monitoring.over the past decades, genes of bacillus thuringiensis var. kurstaki (berliner) (bt) coding for protein toxins have been engineered into maize for protection against the european corn borer (ostrinia nubilalis (hbn.)). however, these transgenic plants may have an impact on non-target organisms. in particular, a potential hazard was identified for non-target lepidopteran larvae, if they consume bt maize pollen on their host plants. risk can be defined as a function of the effect of an event (haza ...200616978572
isolation and characterisation of beauveria bassiana isolates from phylloplanes of hedgerow vegetation.a leaf imprinting technique combined with a selective medium was used to document the natural occurrence of beauveria bassiana on phylloplanes of typical hedgerow plants (grasses, stinging nettle and hawthorn) in may, july and september in a hedgerow in denmark. the density of b. bassiana (as measured by numbers of colony forming units) was greatest in september and on lower nettle leaves. b. bassiana was isolated from phylloplanes in a different hedgerow the following year and a similar picture ...200616378721
screening of herbal extracts for activation of the human peroxisome proliferator-activated receptor.the peroxisome proliferator-activated receptors play a pivotal role in metazoan lipid and glucose homeostasis. synthetic activators of pparalpha (fibrates) and ppargamma (glitazones) are therefore widely used for treatment of dislipidemia and diabetes, respectively. there is growing evidence for herbal compounds to influence nuclear receptor signalling e.g. the ppars. we recently reported carnosic acid and carnosol, both being diterpenes found in the labiate herbs sage and rosemary, to be activa ...200617152989
antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in turkish folk medicine.ethanolic and aqueous extracts from five plant species used in turkish traditional medicine were evaluated for in vivo hypercholesterolaemic and antioxidant activities: agrostemma githago l., potentilla reptans l., thymbra spicata var. spicata l., urtica dioica l. and viscum album var. album l. we assayed the effects of the administration of plant extracts on serum total cholesterol, triglyceride, hdl-c, ldl-c, glucose, ast and alt concentrations in mice fed with cholesterol-rich diet. in additi ...200616713156
antiviral activity in vitro of urtica dioica l., parietaria diffusa m. et k. and sambucus nigra l.parietaria diffusa m. et k., urtica dioica l. (urticaceae) and sambucus nigra l. (caprifoliaceae) are plants usually used in popular medicine of central italy for treating numerous diseases, first of all herpes zoster. several plant products have been described as potential antiviral agents, with special attention being devoted to those having retroviruses as etiological agents, including acquired immunodeficiency syndrome (aids), in which a retrovirus, the designated human immunodeficiency viru ...200515814267
carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in hiv gp120: a new therapeutic concept to hit the achilles heel of hiv.mannose-binding proteins derived from several plants (i.e. hippeastrum hybrid and galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-n) inhibit human immunodeficiency virus (hiv) replication and select for drug-resistant viruses that show profound deletion of n-glycosylation sites in the gp120 envelope (balzarini, j., van laethem, k., hatse, s., vermeire, k., de clercq, e., peumans, w., van damme, e., vandamme, a.-m., bolmstedt, a., and schols, d. (2004) j. virol. 78, 10617-10627; bal ...200516183648
[the frequency of pollen allergy at the population of sarajevo region during the 2002 year].the frequency of pollen alergy in the sample of population of sarajevo region during the 2002 year has been investigated. the age and gender population has been different. for determination of allergy has been use of standard test carryed out in the respective laboratories of clinical center of university of sarajevo. the testing has been on the pollen of weed plant species and grass (graminejae) pollen. in the mixture of pollen weed plant species have been following plants: plantago lanceolata ...200516018386
the effect of exercise and nettle supplementation on oxidative stress markers in the rat brain.chronic swimming training and phytotherapeutic supplementation are assumed to alleviate oxidative damage, and support cell survival in the brain. the effect of forced, chronic swimming training, and enriched lab chow containing 1% (w/w) dried nettle (urtica dioica) leaf were investigated for oxidative stress, inflammation and neurotrophic markers in wistar rat brains. the rats were divided into groups subjected to swimming training (6 weeks) or to nettle supplementation (8 weeks) or to a combina ...200515862920
the use of complementary and alternative (non-conventional) medicine in cancer patients in turkey.the purpose of this study was to define various methods of complementary and alternative medicine (cam) used by cancer patients and their characteristics in turkey. the sample consisted of 100 cancer patients who were monitored in the oncology outpatient and inpatient departments of two hospitals. almost all participating patients were receiving conventional treatment, 36% of which were also using cam methods. female patients and individuals with lower educational background showed a tendency to ...200515899593
inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs.diabetes mellitus is one of the most prevalant diseases of adults. agents with alpha-glucosidase inhibitory activity have been useful as oral hypoglycemic drugs for the control of hyperglycemia in patients with type 2; noninsulin-dependent, diabetes mellitus (niddm). investigation of some medicinal herbs: urtica dioica, taraxacum officinale, viscum album, and myrtus communis with alpha-glucosidase inhibitor activity was conducted to identify a prophylactic effect for diabetes in vitro. all plant ...200515704495
hepatoprotective effects of nigella sativa l and urtica dioica l on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloride-treated rats.to investigate the effects of nigella sativa l (ns) and urtica dioica l (ud) on lipid peroxidation, antioxidant enzyme systems and liver enzymes in ccl(4)-treated rats.200516425366
sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (hiv-1) infection and dendritic-cell-directed hiv-1 transfer.both endocytic uptake and viral fusion can lead to human immunodeficiency virus type 1 (hiv-1) transfer to cd4+ lymphocytes, either through directional regurgitation (infectious transfer in trans [i-it]) or through de novo viral production in dendritic cells (dcs) resulting in a second-phase transfer to cd4+ lymphocytes (infectious second-phase transfer [i-spt]). we have evaluated in immature monocyte-derived dcs both pathways of transfer with regard to their susceptibilities to being blocked by ...200516227272
the role of urtica dioica (urticaceae) in the prevention of oxidative stress caused by tourniquet application in rats.tourniquets are used in extremity surgery and provide a relatively bloodless field, thereby minimizing blood loss and helping identify the vital structures. however, they may cause an ischemia-reperfusion injury with potentially harmful local and systemic consequences. many therapeutic effects such as diuretic, natriuretic, hypotensive, anti-rheumatic, anti-prostatic, and in-vitro anti-oxidant effects of the urtica dioica (ud) have been determined. in the present study, we aimed to investigate t ...200515718813
traditional phytotherapy in central italy (marche, abruzzo, and latium).in this study, the more significant results of extensive ethnopharmacobotanical research carried out by the author in the years 1977-2000 in 175 localities of three regions of central italy (marche, abruzzo, and latium) have been reported and compared. the usages of 80 species belonging to 36 families are described, of which 71 were used in human therapy and 29 in veterinary medicine. uses are suited with the number of localities in which they have been mentioned. among the wild plant mainly sti ...200515664457
molecular cloning and tissue-specific transcriptional regulation of the first peroxidase family member, udp1, in stinging nettle (urtica dioica).a full-length cdna clone, designated udp1, was isolated from urtica dioica (stinging nettle), using a polymerase chain reaction based strategy. the putative udp1 protein is characterized by a cleavable n-terminal signal sequence, likely responsible for the rough endoplasmic reticulum entry and a 310 amino acids mature protein, containing all the important residues, which are evolutionary conserved among different members of the plant peroxidase family. a unique structural feature of the udp1 per ...200516219430
evaluating the efficiency of a combination of pygeum africanum and stinging nettle (urtica dioica) extracts in treating benign prostatic hyperplasia (bph): double-blind, randomized, placebo controlled trial.in spite of its historical use, published data about phytotherapic products is characterized by the absence of well conducted studies, leading to conflictive and indefinite results about efficiency and safety of theses drugs. in that sense, we have analyzed the results of a combination of pygeum africanum and stinging nettle (urtica dioica) extracts in patients with benign prostatic hyperplasia (bph), based in a double-blind, randomized, placebo-controlled protocol.200515748367
carabid larvae as predators of weed seeds: granivory in larvae of amara eurynota (coleoptera: carabidae).up to date we do not have much information about predation on seeds by larvae of ground beetles. one of the reasons why such knowledge is important is that granivorous larvae contribute to predation of weed seeds. in this study, the food requirements of larvae of autumn breeding carabid species amara eurynota (panzer) were investigated in the laboratory and a hypothesis, that they are granivorous was tested. insect diet (tenebrio molitor larvae), three seed diets (seeds of artemisia vulgaris, tr ...200415759391
complementary and alternative interventions in asthma, allergy, and immunology.to review which herbs are most commonly used as complementary and alternative medicine (cam) for treatment of asthma, allergy, and immunologic conditions.200415330011
antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (urtica dioica l.).in this study, water extract of nettle (urtica dioica l.) (wen) was studied for antioxidant, antimicrobial, antiulcer and analgesic properties. the antioxidant properties of wen were evaluated using different antioxidant tests, including reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities. wen had powerful antioxidant activity. the 50, 100 and 250 microg amounts of wen showed 39, 66 and 98% inhibition on perox ...200415013182
platelet anti-aggregant property of some moroccan medicinal plants.it is known that blood platelets may present some dysfunction linked to cardiovascular pathologies such as arterial hypertension. the aim of this work is to examine the in vitro anti-aggregant effect of five medicinal plants among which three were reported as antihypertensive in oriental morocco: arbutus unedo (ericaceae), urtica dioïca (urticaceae), and petroselinum crispum (apiaceae). the two other plants were cistus ladaniferus (cistaceae) and equisetum arvense (equisetaceae). the results obt ...200415325737
antioxidant properties of some medicinal plants: prangos ferulacea (apiaceae), sedum sempervivoides (crassulaceae), malva neglecta (malvaceae), cruciata taurica (rubiaceae), rosa pimpinellifolia (rosaceae), galium verum subsp. verum (rubiaceae), urtica dioica (urticaceae).antioxidant and 2,2-diphenyl-1-picrylhydrazyl (dpph) radical scavenging activities, reducing powers and the amount of total phenolic compounds of aqueous and/or methanolic extracts of some medicinal plants used in eastern turkey were studied. these plants are prangos ferulacea (casir), sedum sempervivoides (horoz lelesi), malva neglecta (ebemgumeci), cruciata taurica (sarilik otu), rosa pimpinellifolia (koyun gozu), galium verum subsp. verum (madavur otu), urtica dioica (isirgan). the highest pe ...200415133249
traditional medicine in sakarya province (turkey) and antimicrobial activities of selected species.traditional medicine in north-west of turkey (sakarya province) were studied during a 2 months field study by interviewing local informants from several villages. plant species used to treat infections were tested for antimicrobial activity. information was collected for 46 plant species from 30 families and for 5 animal species. twenty four of the plant species were cultivated. most used families were asteraceae, cucurbitaceae, lamiaceae and rosaceae and the most used plants were artemisia absi ...200415507351
functional analyses of the chitin-binding domains and the catalytic domain of brassica juncea chitinase bjchi1.we previously isolated a brassica juncea cdna encoding bjchi1, a novel chitinase with two chitin-binding domains. synthesis of its mrna is induced by wounding, methyl jasmonate treatment, aspergillus niger infection and caterpillar (pieris rapae) feeding, suggesting that the protein has a role in defense. in that it possesses two chitin-binding domains, bjchi1 resembles the precursor of urtica dioica agglutinin but unlike that protein, bjchi1 retains its chitinase catalytic domain after post-tra ...200415604744
the role of urtica dioica and nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats.the role of nigella sativa l. (ranunculaceae) (ns) and urtica dioica l. was investigated (ud) in the prevention of carbon tetrachloride (ccl4) induced liver fibrosis and cirrhosis. fifty sprague-dawley rats were allocated into fi ve groups (i, iia and b, iiia and b) and ccl4 was injected biweekly to all groups. group i (control, ccl4 only), group iia and b (ns fixed oil and volatile oil), group iiia and b (ud fixed oil and ud decoction extract) rats were killed at the end of week 12 and histopat ...200313680830
complementary alternative treatments used by patients with cancer in eastern turkey.interest in complementary-alternative medicine therapies is growing rapidly in turkey. therefore, the purpose of this research was to determine the types and prevalence of alternative therapies used by the patients with a diagnosis of cancer, and to determine factors influencing the choices of their therapies in erzurum, turkey. approximately 10-minute face-to-face interviews were conducted with each subject in the radiation oncology department. the factors associated with the use of alternative ...200312832956
modulatory effect of urtica dioica l. (urticaceae) leaf extract on biotransformation enzyme systems, antioxidant enzymes, lactate dehydrogenase and lipid peroxidation in mice.the effects of two doses (50 and 100 mg/kg body wt given orally for 14 days) of an ethanol-water (80%-20%) extract of urtica dioica l. and butylated hydroxyanisole (bha) were investigated, for phase i and phase ii enzymes, antioxidant enzymes, lactate dehydrogenase, lipid peroxidation and sulfhydryl groups in the liver of swiss albino mice (8-9 weeks old). a modulatory effect of two doses and bha was also observed for the activities of glutathione s-transferase, dt-diaphorase, superoxide dismuta ...200312834006
some medicinal plants as immunostimulant for fish.immunostimulant effects of the dietary intake of various medicinal plant extracts on fish, rainbow trout (oncorhynchus mykiss), were investigated. for this purpose fish were fed with diets containing aqueous extracts of mistletoe (viscum album), nettle (urtica dioica), and ginger (zingiber officinale). food containing lyophilized extracts of these plants as 0.1 and 1% was used at a rate of 2% of body weight per day for three weeks. at the end of the experimental period, various parameters of non ...200312902058
induction of insulin secretion by a component of urtica dioica leave extract in perifused islets of langerhans and its in vivo effects in normal and streptozotocin diabetic rats.the blood glucose lowering effect of urtica dioica (stinging nettle) as a medicinal plant has been noted in old writings such as those of avicenna. recently, there has also been other investigators that indicated the hypoglycemic effect of urtica dioica. but so far, the mechanism of this effect has not been deduced. in this report, a perifusion system is arranged in which an exact number of langerhans islets were exposed to several fractions of extracts of urtica dioica by tlc. the active ingred ...200314522431
effects of nigella sativa l. and urtica dioica l. on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in ccl4-treated rats.this study was designed to investigate the effects nigella sativa l. (ns) and urtica dioica l. (ud) on lipid peroxidation, antioxidant enzyme systems and some liver enzymes in carbon tetrachloride (ccl4)-treated rats. a total of 60 healthy male sprague-dawley rats were utilized in this study. the rats were randomly allotted into one of four experimental groups: a (ccl4-only treated), b (ccl4 + ud treated), c (ccl4 + ns treated) and d (ccl4 + ud + ns treated), each containing 15 animals. all grou ...200314567515
antihyperglycemic activity of the aqueous extract of urtica dioica.when administered 30 min before glucose loading, the aqueous extract of urtica dioica (nettle) (250 mg/kg) showed a strong glucose lowering effect. the decrease of glycemia has reached to 33+/-3.4% of the control value 1 h after glucose loading. this effect was persistent during 3 h. in contrast, nettle did not show hypoglycemic effect in alloxan-induced diabetic rats. the amount of glucose absorbed in a segment jejunum in situ was 8.05+/-0.68 mg in presence of nettle extract vs. 11.11+/-0.75 mg ...200314630172
effects of nigella sativa l. and urtica dioica l. on selected mineral status and hematological values in ccl4-treated rats.this study was designed to investigate the effects of nigella sativa l. (ns), known as black seed, or/and urtica dioica l. (ud), known as stinging nettle root, treatments on serum na, k, cl, and ca levels and some hematological values of ccl4-treated rats. sixty healthy male sprague-dawley rats, weighing 250-300 g, were randomly allotted into 1 of 4 experimental groups: a (ccl4-only treated), b (ccl4+ud treated), c (ccl4+ns treated), and d (ccl4+ud+ns treated), each containing 15 animals. all gr ...200314716106
effect of urtica dioica agglutinin and arabidopsis thaliana chia4 chitinase on the protozoan phytomonas françai.the genus phytomonas is responsible for many diseases in different crop plant species. the finding that chitin is an exposed cell surface polysaccharide in phytomonas françai and the observation that chitinases can inhibit fungal growth raises expectations about the potential effect of plant chitinases on the p. françai cell membrane surface. the plant chitinases urtica dioica agglutinin (uda) and arabidopsis thaliana chia4 (atchit4) proteins were over-expressed in bacteria and the interaction b ...200313129600
glutathione s-transferases and malondialdehyde in the liver of nod mice on short-term treatment with plant mixture extract p-9801091.changes in the concentration of glutathione s-transferases (gsts) and malondialdehyde (mda) were assessed in the liver of normal and diabetic nod mice with and without treatment with the plant extract p-9801091. the plant extract p-9801091 is an antihyperglycaemic preparation containing myrtilli folium (vaccinium myrtillus l.), taraxaci radix (taraxacum of fi cinale web.), cichorii radix (cichorium intybus l.), juniperi fructus (juniperus communis l.), centaurii herba (centaurium umbellatum gili ...200312722130
respiratory and allergic diseases: from upper respiratory tract infections to asthma.patients with asthma and allergic rhinitis may benefit from hydration and a diet low in sodium, omega-6 fatty acids, and transfatty acids, but high in omega-3 fatty acids (i.e., fish, almonds, walnuts, pumpkin, and flax seeds), onions, and fruits and vegetables (at least five servings a day). physicians may need to be more cautious when prescribing antibiotics to children in their first year of life when they are born to families with a history of atopy. more research is needed to establish whet ...200212391710
effects of the antirheumatic remedy hox alpha--a new stinging nettle leaf extract--on matrix metalloproteinases in human chondrocytes in vitro.inflammatory joint diseases are characterized by enhanced extracellular matrix degradation which is predominantly mediated by cytokine-stimulated upregulation of matrix metalloproteinase (mmp) expression. besides tumour necrosis factor-alpha (tnf-alpha), interleukin-1beta (il-1beta) produced by articular chondrocytes and synovial macrophages, is the most important cytokine stimulating mmp expression under inflammatory conditions. blockade of these two cytokines and their downstream effectors are ...200211962753
immunosuppressant effect of ids 30, a stinging nettle leaf extract, on myeloid dendritic cells in vitro.dendritic cells are important antigen presenting cells that play a role in the initiation of rheumatoid arthritis (ra). the stinging nettle leaf extract ids 30 (hox alpha) has been recommended for adjuvant therapy of rheumatic diseases. we investigated the immunomodulating effect of ids 30 extract on the maturation of hematopoietic dendritic cells.200211950004
cardiovascular effects of urtica dioica l. (urticaceae) roots extracts: in vitro and in vivo pharmacological studies.urtica dioica (urticaceae) is a plant principally used in the traditional medicine of oriental marocco as antihypertensive remedy (j. ethnopharmacol., 58 (1997), 45). the aim of this work was to evaluate a possible direct cardiovascular action of the plant and to investigate its mechanism of action. in aortic preparations with intact and functional endothelial layer, pre-contracted with kcl 20 mm or norepinephrine 3 microm, the crude aqueous and methanolic extracts of the plant roots, as well as ...200212020933
tobacco-expressed brassica juncea chitinase bjchi1 shows antifungal activity in vitro.we have previously isolated a brassica juncea cdna encoding bjchi1, a novel chitinase with two chitin-binding domains, and have shown that its mrna is induced by wounding and methyl jasmonate treatment (k.-j. zhao and m.-l. chye, plant mol. biol. 40 (1999) 1009-1018). by the presence of two chitin-binding domains, bjchi1 resembles the precursor of uda (urtica dioica agglutinin) but, unlike uda, bjchi1 retains its chitinase catalytic domain after post-translational processing. here, we indicate t ...200212175020
in vitro antioxidant activity of non-cultivated vegetables of ethnic albanians in southern italy.a total of 27 extracts from non-cultivated and weedy vegetables traditionally consumed by ethnic albanians (arbëreshë) in the vulture area (southern italy) were tested for their free radical scavenging activity (frsa) in the dpph (1,1-diphenyl-2-picrylhydrazil radical) screening assay, for their in vitro non-enzymatic inhibition of bovine brain lipid peroxidation and for their inhibition of xanthine oxidase (xo). in both antioxidant assays strong activity was shown for leopoldia comosa (bulbs, s ...200212203269
cardiovascular effects of urtica dioica l. in isolated rat heart and aorta.urtica dioica l. or nettle (urticaceae) is widely used in oriental morocco to treat hypertension. aqueous extract of nettle (aen) also exerts a hypotensive action in the rat in vivo. the aim of this work was to characterize the specific cardiac and vascular effects of aen. in the isolated langendorff perfused rat heart, aen (1 and 2 g/l) markedly decreased heart rate and increased left ventricular pressure. higher concentration (5 g/l) even led to cardiac arrest. although carbachol mimicked the ...200212237804
factors associated with utilization of nonproven cancer therapies in turkey. a study of 135 patients from a single center.in their search for a cure, a significant number of cancer patients use nonproven treatment (npt) methods. however, little is known about patient and disease characteristics associated with the use of these methods. in this trial, we evaluated the prevalence of and the factors associated with the usage of nonproven cancer remedies in a teaching hospital in turkey. a self-administered questionnaire was given to 135 cancer patients attending the outpatient clinics of a medical oncology department. ...200111585272
remarkable, overlooked and new microfungi in north rhine-westphalia, germany.during our investigations of the micro flora in nrw in the years of 1999 and 2000 we were able to collect and identify some new and rare species of micro fungi as parasites and saprophytes on wild and ornamental plants. some of them are new for germany: podosphaera xanthii on coreopsis verticillata; cercospora traversiana on trigonella foenum-graecum; passalora dubia on atriplex hortensis; ophiobolus cirsii on carduus spec.; periconia britannica on polemonium coeruleum; ascochyta leptospora on a ...200112425026
effect of 'antidiabetis' herbal preparation on serum glucose and fructosamine in nod mice.the antihyperglycemic effect of the antidiabetis herbal preparation ((myrtilli folium (vaccinium myrtillus l.), taraxaci radix (taraxacum officinale web.), cichorii radix (cichorium intybus l.), juniperi fructus (juniperus communis l.), centaurii herba (centaurium umbellatum gilib.), phaseoli pericarpium (phaseolus vulgaris), millefollii herba (achillea millefolium l.), morii folium (morus nigra l.), valeriane radix (valleriana officinalis l.), urticae herba et radix (urtica dioica l.)), patent ...200111297848
poaceae in the natural diet of the snail helix aspersa müller (gastropoda, pulmonata).the natural diet of helix aspersa was studied in two populations by analysing faeces. picris echioides, carduus tenuifloris, urtica dioica, galium molugo (dicotyledons) and poaceae (monocotyledons) were the principal resources of the studied populations. the species of poaceae ingested by helix aspersa in july were determined by analysing the phytoliths present in the faeces. festuca rubra, dactylis glomerata and bromus hordeaceus seemed to be attractive for the snails whereas elytrigia repens w ...200111725705
the influence of suspended particles on the acute toxicity of 2-chloro-4-nitro-aniline, cadmium, and pentachlorophenol on the valve movement response of the zebra mussel (dreissena polymorpha).the dreissena-monitor is a biological early warning system for the continuous monitoring of river water quality, based on the valve movements of two groups of 42 zebra mussels (dreissena polymorpha). laboratory experiments with cd, pcp, and 2-chloro-4-nitro-aniline were conducted in combination with suspended particles (a mixture of stinging nettle powder, bentonite, and quartz powder). an increase of suspended particles up to a nominal concentration of 540 mg/l within 5 min did not evoke any re ...200111525492
current lead natural products for the chemotherapy of human immunodeficiency virus (hiv) infection.a large variety of natural products have been described as anti-hiv agents, and for a portion thereof the target of interaction has been identified. cyanovirin-n, a 11-kda protein from cyanobacterium (blue-green alga) irreversibly inactivates hiv and also aborts cell-to-cell fusion and transmission of hiv, due to its high-affinity interaction with gp120. various sulfated polysaccharides extracted from seaweeds (i.e., nothogenia fastigiata, aghardhiella tenera) inhibit the virus adsorption proces ...200010934347
phytotherapeutic agents in the treatment of benign prostatic hyperplasia.the rationale and efficacy of phytotherapeutic agents in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia (bph) are continuously debated. while plant extracts are prescribed and reimbursable treatment options in europe, they are officially classified merely as dietary supplements in the united states. the most commonly used preparations originate from the species serenoa repens, pygeum africanum, hypoxis rooperi, pinus, picea, urtica dioica, and secale cere ...200012084323
antiproliferative effect on human prostate cancer cells by a stinging nettle root (urtica dioica) extract.in the present study the activity of a 20% methanolic extract of stinging nettle roots (urtica dioica l., urticaceae) on the proliferative activity of human prostatic epithelial (lncap) and stromal (hpcps) cells was evaluated using a colorimetric assay. a concentration-dependent and significant (p < 0.05) antiproliferative effect of the extract was observed only on lncap cells during 7 days, whereas stromal cell growth remained unaltered. the inhibition was time-dependent with the maximum of gro ...200010705733
acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of urtica dioica in the rat.this study was performed on anaesthetized male wistar rats that received a continuous intravenous perfusion during 1.25 h of an aqueous extract of aerial parts of urtica dioica l. (urticaceae) at a low dose of 4 mg/kg/h or at a high dose of 24 mg/kg/h, or furosemide (control diuretic) at a dose of 2 mg/kg/h. as compared with a control period in each rat, the arterial blood pressure was reduced proportionally to the dose of the perfusion of the plant extract (15 and 38%, p<0.001, respectively). t ...200011025144
antiproliferative effect of a polysaccharide fraction of a 20% methanolic extract of stinging nettle roots upon epithelial cells of the human prostate (lncap).in germany, plant extracts are often used in the treatment of early stages of benign prostate hyperplasia (bph). the effects of different concentrations of the polysaccharide fraction of the 20% methanolic extract of stinging nettle roots (poly-m) on the cellular proliferation of lymph node carcinoma of the prostate (lncap) cells were determined by measurement of the genomic dna content of the samples. all concentrations of poly-m showed an inhibitory effect on the growth of the lncap cells duri ...199910563375
saw palmetto extracts potently and noncompetitively inhibit human alpha1-adrenoceptors in vitro.we wanted to test whether phytotherapeutic agents used in the treatment of lower urinary tract symptoms have alpha1-adrenoceptor antagonistic properties in vitro.199910068345
processing, targeting, and antifungal activity of stinging nettle agglutinin in transgenic tobacco.the gene encoding the precursor to stinging nettle (urtica dioica l. ) isolectin i was introduced into tobacco (nicotiana tabacum). in transgenic plants this precursor was processed to mature-sized lectin. the mature isolectin is deposited intracellularly, most likely in the vacuoles. a gene construct lacking the c-terminal 25 amino acids was also introduced in tobacco to study the role of the c terminus in subcellular trafficking. in tobacco plants that expressed this construct, the mutant prec ...199910364393
methyl jasmonate induces expression of a novel brassica juncea chitinase with two chitin-binding domains.we have cloned a 1.3 kb brassica juncea cdna encoding bjchi1, a novel acidic chitinase with two chitin-binding domains that shows 62% identity to nicotiana tabacum chia1 chitinase. bjchi1 is structurally unlike chia1 that has one chitin-binding domain, but resembles chia5 chitinase uda1, the precursor of urtica dioica agglutinin: however there is only 36.9% identity between them. we propose that bjchi1 should be classified under a new class, chia7. the spacer and the hinge region of bjchi1 are p ...199910527425
pollen calendar of the city of salamanca (spain). aeropalynological analysis for 1981-1982 and 1991-1992.we report a study on the contents of airborne pollen in the city of salamanca (spain) aimed at establishing a pollen calendar for the city for the yearly periods of maximum concentrations, relating these with quantifiable atmospheric variables over two two-year periods with an interval of 10 years between them: 1981-82 and 1991-92. the pollen was captured with burkard spore-traps, based on hirst's volumetric method. determinations were made daily and were used to make preparations, previously st ...19989885728
regulation of gelatinase b (mmp-9) in leukocytes by plant lectins.the stimulatory or inhibitory effects of plant lectins on the production of gelatinase a (mmp-2) and gelatinase b (mmp-9) by mononuclear white blood cells was investigated by substrate zymography. leukocyte cultures from 24-h old buffy coats were spontaneously activated and produced high levels of gelatinase b. using such cultures the suppressing activity of the datura stramonium, viscum album, bauhinia purpurea, triticum aestivum and maackia amurensis lectins on gelatinase b induction were demo ...19989607327
site-directed mutagenesis of active site residues in a class i endochitinase from chestnut seeds.despite the intensive research on plant chitinases, largely bolstered by their antifungal properties, little is known at present about the structure-activity relationships of these enzymes. here we report the identification of essential active site residues in endochitinase ch3, a class i enzyme abundant in chestnut seeds. knowledge-based protein modeling as well as structural and sequence comparisons were performed to identify potential catalytic residues. different mutated proteins were then g ...19989719683
carbohydrate-protein interaction studies by laser photo cidnp nmr methods.the side chains of tyrosine, tryptophan and histidine are able to produce cidnp (chemically induced dynamic nuclear polarization) signals after laser irradiation in the presence of a suitable radical pair-generating dye. elicitation of such a response in proteins implies surface accessibility of the respective groups to the light-absorbing dye. in principle, this technique allows the monitoring of the effect of ligand binding to a receptor and of site-directed mutagenesis on conformational aspec ...19979249155
the inhibiting effects of urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse.extracts of stinging nettle roots (urtica dioica l. urticaceae) are used in the treatment of benign prostatic hyperplasia (bph). we established a bph-model by directly implanting an urogenital sinus (ugs) into the ventral prostate gland of an adult mouse. five differently prepared stinging nettle root extracts were tested in this model. the 20% methanolic extract was the most effective with a 51.4% inhibition of induced growth.19979270373
lignans from the roots of urtica dioica and their metabolites bind to human sex hormone binding globulin (shbg).polar extracts of the stinging nettle (urtica dioica l.) roots contain the ligans (+)-neoolivil, (-)-secoisolariciresinol, dehydrodiconiferyl alcohol, isolariciresinol, pinoresinol, and 3,4-divanillyltetrahydrofuran. these compounds were either isolated from urtica roots, or obtained semisynthetically. their affinity to human sex hormone binding globulin (shbg) was tested in an in vitro assay. in addition, the main intestinal transformation products of plant lignans in humans, enterodiol and ent ...19979434605
phytotherapy of hypertension and diabetes in oriental morocco.in order to select the main medicinal plants used in folk medicine to treat arterial hypertension and/or diabetes, a survey was undertaken in different areas of oriental morocco. the patients (370 women and 256 men) were divided into three groups: diabetics (61%), hypertensives (23%) and hypertensive diabetic persons (16%). on average, 67.51% of patients regularly use medicinal plants. this proportion is perceptibly the same in all groups and does not depend on sex, age and socio-cultural level. ...19979324004
an investigation of some turkish herbal medicines in salmonella typhimurium and in the comet assay in human lymphocytes.medicinal plants play a major role in the life of turkish people and of late medicinal plant usage has increased in many countries. green plants in general contain mutagenic and carcinogenic substances, but there is little information about the biological activities of herbal medicine. in the present study, therefore, various turkish medicinal herbs were investigated for their genotoxic potential in the salmonella typhimurium microsomal activation assay and the alkaline single cell gel electroph ...19968875742
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