Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter | 
|---|
| the bacteriology of salivary gland infections. | the parotid gland is the salivary gland most commonly affected by inflammation. however, infection of the salivary glands can occur in any of the glands. the most common pathogens associated with acute bacterial infection are staphylococcus aureus and anaerobic bacteria. the predominant anaerobes include: anaerobic gram negative bacilli (eg, pigmented prevotella and porphyromonas); fusobacterium spp; and peptostreptococcus spp. in addition, streptococcus spp (including streptococcus pneumoniae) ... | 2009 | 19608044 | 
| effect of age on gingival crevicular fluid concentrations of mif and pge2. | we used an experimental gingivitis study design to compare crevicular fluid concentrations of migration inhibitory factor (mif) and prostaglandin e(2) (pge(2)) in younger (18 to 30 yrs) and older (46 to 77 yrs) healthy adults. pge(2) increased after 1 wk in younger participants, whereas it decreased in older individuals after 1 wk of plaque accumulation. a significant interaction between age and time was observed for pge(2) (p = 0.04). high concentrations of mif were identified in both age group ... | 2009 | 19641151 | 
| bone microbial contamination influences autogenous grafting in sinus augmentation. | the oral occurrence of putative microbial pathogens in humans has been documented in health and disease. the presence of periodontopathogens in patients with a history of periodontal disease may have a negative impact on bone regeneration. this investigation was conducted to confirm the presence of periodontal pathogens in bone particles harvested intraorally for maxillary sinus augmentation and to assess the clinical and radiographic outcomes 6 to 12 months after bone augmentation. | 2009 | 19656037 | 
| presence of aggregatibacter actinomycetemcomitans in young individuals: a 16-year clinical and microbiological follow-up study. | to look for clinical signs of periodontal disease in young adults who exhibited radiographic bone loss and detectable numbers of aggregatibacter actinomycetemcomitans in their primary dentition. | 2009 | 19678862 | 
| significance of cytomorphological and microbiological examination of bile collected by endoscopic cannulation of the papilla of vater. | bile analysis yields important information such as "biliary microlithiasis" and biliary tract colonization by microorganisms like salmonella typhi or paratyphi, escherichia coli, etc., which may progresses to cholelithiasis and have been found to have a role in the development of gallbladder cancer in india. | 2009 | 19679953 | 
| identification of a mechanical rheostat in the hydrophobic core of protein l. | the ability of proteins and their complexes to withstand or respond to mechanical stimuli is vital for cells to maintain their structural organisation, to relay external signals and to facilitate unfolding and remodelling. force spectroscopy using the atomic force microscope allows the behaviour of single protein molecules under an applied extension to be investigated and their mechanical strength to be quantified. protein l, a simple model protein, displays moderate mechanical strength and is t ... | 2009 | 19683005 | 
| the ability of non-bacteriocin producing streptococcus bovis strains to bind and transfer bovicin hc5 to other sensitive bacteria. | streptococcus bovis hc5 produces a broad spectrum lantibiotic (bovicin hc5), but s. bovis jb1 does not have antimicrobial activity. preliminary experiments revealed an anomaly. when s. bovis jb1 cells were washed in stationary phase s. bovis hc5 cell-free culture supernatant, the s. bovis jb1 cells were subsequently able to inhibit hyper-ammonia producing ruminal bacteria (clostridium sticklandii, clostridium aminophilum and peptostreptococcus anaerobius). other non-bacteriocin producing s. bovi ... | 2009 | 19171197 | 
| lysozyme and microbiota in relation to gingivitis and periodontitis. | the aim of this study was to investigate associations between the immune component of the oral cavity, lysozyme, in gingival crevicular fluid and unstimulated saliva, and colonization dynamics of periodontopathogenic bacteria from supra- and subgingival plaque samples in patients with gingivitis or periodontitis. | 2009 | 19179970 | 
| the antimicrobial effects of hops (humulus lupulus l.) on ruminal hyper ammonia-producing bacteria. | to assess the antimicrobial effects of hops (humulus lupulus l.) on hyper ammonia producing-bacteria (hab), which catabolize amino acids and peptides in the bovine rumen. | 2009 | 19413813 | 
| mechanical characterization of protein l in the low-force regime by electromagnetic tweezers/evanescent nanometry. | mechanical manipulation at the single molecule level of proteins exhibiting mechanical stability poses a technical challenge that has been almost exclusively approached by atomic force microscopy (afm) techniques. however, due to mechanical drift limitations, afm techniques are restricted to experimental recordings that last less than a minute in the high-force regime. here we demonstrate a novel combination of electromagnetic tweezers and evanescent nanometry that readily captures the forced un ... | 2009 | 19413987 | 
| the microbiota on different oral surfaces in healthy children. | knowledge of the early oral colonization patterns could provide a better understanding of oral biofilm development and disease initiation that in turn could be the basis for early preventive programmes. | 2009 | 19416446 | 
| ten-year follow-up of a patient with osler-weber-rendu syndrome and recurrent cerebral abscess secondary to pulmonary arteriovenous fistula. | in 1998, one of us (mjm) published an article discussing several patients with osler-weber-rendu syndrome or hereditary haemorrhagic telangiectasia with secondary cerebral complications. these were intracerebral haemorrhage, ischaemic infarct and intracerebral abscess. we outlined the background of the syndrome as well as its genotype and predicted an increasingly important role for genetic testing. our aim in this paper is to examine the progress of one of the patients as well as recommending f ... | 2009 | 19428258 | 
| the effects of treatment of acute otitis media with a low dose vs a high dose of amoxicillin on the nasopharyngeal flora. | to compare the effects on the nasopharyngeal flora of therapy of acute otitis media in children with either a low dose or a high dose of amoxicillin. | 2009 | 19451466 | 
| fetal exposure to oral pathogens and subsequent risk for neonatal intensive care admission. | maternal periodontal infection has been associated with adverse maternal and neonatal outcomes. in utero fetal exposure to oral pathogens was also recognized as deleterious to the fetus. the objective of this study was to determine the relationship between fetal exposure to oral pathogens and neonatal intensive care unit (nicu) admission. | 2009 | 19485816 | 
| [oral cavity microbiocenose in healthy teenagers and patients with chronic gastritis and gastroduodenitis]. | microbial association distinctive features and colonization degree of different oral cavity biotope were established in healthy teenagers and patients with chronic gastritis and gastroduodenitis. there were studied mucous membrane surfaces of cheek, tongue, content of gingival crevice, oral fluid and dental plaque of 24 healthy persons of the age 12-17 years and 29 patients of the same age with gastritis and gastroduodenitis. on the mucous membranes of the ill teenagers there were found porphiro ... | 2009 | 19491778 | 
| starvation response and growth in serum of fusobacterium nucleatum, peptostreptococcus anaerobius, prevotella intermedia, and pseudoramibacter alactolyticus. | the microbiota inhabiting the untreated root canal differ markedly from those found in post-treatment disease, yet there is limited information on the microbial characteristics distinguishing the different infections. we hypothesized that starvation survival is a key microbial property in species selection. this study analyzed starvation-survival behavior over 60 days of species representative of the untreated root canal infection: fusobacterium nucleatum, peptostreptococcus anaerobius, prevotel ... | 2009 | 19540450 | 
| comparison between polymerase chain reaction-based and checkerboard dna hybridization techniques for microbial assessment of subgingival plaque samples. | to compare polymerase chain reaction (pcr) with subsequent reverse hybridization (micro-ident test) and checkerboard dna-dna hybridization for the identification of 13 bacterial species in subgingival plaque samples. | 2009 | 19563330 | 
| molecular analysis of persistent periradicular lesions and root ends reveals a diverse microbial profile. | the microbial etiology of periradicular lesions is recognized; however, the bacterial profile of these lesions is not well elucidated. the purpose of this study was to determine the frequency of bacterial colonization in these lesions and to characterize the bacterial community present in root ends and periradicular lesions. | 2009 | 19567313 | 
| does diclofenac increase the risk of cervical necrotizing fasciitis in a rat model? | non-steroidal anti-inflammatory drugs (nsaids) are known for aggravating in vitro infections and were reported in many cases of cervical necrotizing fasciitis (cnf). we developed a rat model of cnf, mimicking as closely as possible the human-cnf, to study the effect of a nsaids, diclofenac, as a promoting factor. twenty rats were injected bilaterally in the neck with peptostreptococcus and with a fresh saliva specimen for another 20 rats. half of each group was given an intramuscular injection o ... | 2009 | 19200252 | 
| microbial transformation and bioactivation of isoflavones from pueraria flowers by human intestinal bacterial strains. | the flowers from pueraria, which are called puerariae flos, have been used since ancient times for recovery from alcohol intoxication. we elucidated the microbial transformation of the main isoflavones (1, 1a and 2) by using 29 commercially available human intestinal bacterial strains together with the bioactivation of the hepatoprotective activity of their metabolites. tectoridin (1a), which contains only one glucosyl moiety, was metabolized to its aglycone 1b by various bacterial strains. on t ... | 2009 | 19219523 | 
| the bacteriology of chronic rhinosinusitis with and without nasal polyps. | to compare the bacteriologic findings in ethmoidal biopsy specimens and nasal lavage samples from healthy control patients and from patients with chronic rhinosinusitis (crs) with nasal polyps (crsnp+) and without nasal polyps (crsnp-). | 2009 | 19221239 | 
| does pregnancy have an impact on the subgingival microbiota? | we investigated clinical and subgingival microbiologic changes during pregnancy in 20 consecutive pregnant women > or =18 years not receiving dental care. | 2009 | 19228092 | 
| clinical features and prognostic factors of anaerobic infections: a 7-year retrospective study. | risk factors for mortality resulting from anaerobic infection are incompletely defined. the clinical significance of a broad range of pathogenic obligate anaerobic organisms was examined, and factors independently associated with mortality were identified in patients with clinically significant anaerobic infections. | 2009 | 19270476 | 
| into thin air. | 2009 | 19272085 | |
| [septic shock caused by gardnerella vaginalis and peptostreptococcus species after cesarean section]. | a 41-year old multisectio patient got a life-threatening postoperative infection with gardnerella vaginalis and peptostreptococcus spp. perioperative treatment with cefuroxime and metronidazol is recommended. | 2009 | 19284925 | 
| bacterial conversion of secoisolariciresinol and anhydrosecoisolariciresinol. | it has been investigated whether secoisolariciresinol (seco) and anhydrosecoisolariciresinol (ahs), an acid degradation product of seco, could be fermented in a similar way, and to a similar extent, by members of the intestinal microbiota. | 2009 | 19302311 | 
| branchial cleft cysts in adults. diagnostic procedures and treatment in a series of 18 cases. | branchial cleft anomalies may be presented as branchial cysts, fistulas, or sinuses. purpose of this paper is to present the diagnostic procedures and the treatment in a series of branchial cleft cysts. | 2009 | 19308468 | 
| in vitro bactericidal activity of recombinant human beta-defensin-3 against pathogenic bacterial strains in human tooth root canal. | human beta-defensin-3 (hbd3), an endogenous antimicrobial peptide, has strong broad-spectrum antimicrobial activity. this study aimed to obtain recombinant hbd3 (rhbd3) and to test the hypothesis that the antimicrobial characteristics of hbd3 may offer an advantage over conventional medicine in reducing intracanal bacteria. genetic engineering was used to obtain active rhbd3 and analysis revealed that it exhibited a broad spectrum of antibacterial activity at low micromolar concentrations agains ... | 2009 | 18775647 | 
| targeted antimicrobial activity of a specific igg-smap28 conjugate against porphyromonas gingivalis in a mixed culture. | antimicrobial peptides coupled to a ligand, receptor or antibody for a specific pathogenic bacteria could be used to develop narrow-spectrum pharmaceuticals with 'targeted' antimicrobial activity void of adverse reactions often associated with the use of broad-spectrum antibiotics. to assess the feasibility of this approach, in this study sheep myeloid antimicrobial peptide (smap) 28 was linked to affinity- and protein g-purified rabbit immunoglobulin g (igg) antibodies specific to the outer sur ... | 2009 | 18778918 | 
| pericarditis caused by anaerobic bacteria. | this review describes the microbiology, diagnosis and management of pericarditis due to anaerobic bacteria. the predominant anaerobes isolated from patients with pericarditis are gram-negative bacilli (mostly bacteroides fragilis group) as well as peptostreptococcus, clostridium, fusobacterium, bifidobacterium and actinomyces spp. anaerobic bacteria can be recovered from pericarditis resulting from the following mechanisms: (i) spread from a contiguous site of infection, either de novo or follow ... | 2009 | 18789852 | 
| uncultivated bacteria as etiologic agents of intra-amniotic inflammation leading to preterm birth. | intra-amniotic infection and inflammation are major causes of preterm birth (ptb). however, intra-amniotic inflammation is often detected in the absence of infection. this may partly be due to the culturing methods employed in hospital laboratories, which are unable to detect the uncultivated species. in this study, intra-amniotic microbial infections associated with ptb were examined by both culture and 16s rrna-based culture-independent methods and were corroborated by the presence of intra-am ... | 2009 | 18971361 | 
| two teenagers with sepsis and pneumonia. | 2009 | 19114923 | |
| effectiveness of ozone against endodontopathogenic microorganisms in a root canal biofilm model. | to assess the antimicrobial efficacy of aqueous (1.25-20 microg ml(-1)) and gaseous ozone (1-53 g m(-3)) as an alternative antiseptic against endodontic pathogens in suspension and a biofilm model. | 2009 | 19125975 | 
| the microbiota of acute apical abscesses. | as the breadth of bacterial diversity in the oral cavity has been deciphered by molecular studies, several newly identified species/phylotypes have emerged as potential pathogens. we hypothesized that many of these species/phylotypes could also be involved with the etiology of endodontic abscesses. abscess aspirates from 42 persons were analyzed for the presence of 81 species/phylotypes by means of a reverse-capture checkerboard hybridization assay. associations between the most frequently detec ... | 2009 | 19131319 | 
| clinical and microbiological determinants of ailing dental implants. | the failure of the host tissue to establish or maintain osseointegration around dental implants is due to either occlusal or parafunctional forces, premature loading, ill-directed stress, or microbial infection. the long-term failure rate of dental implants is generally 5-10%. although a variety of etiologies of early peri-implant bone loss (from implant placement to 1-year post-loading) have been proposed, factors associated with late implant failures are less well understood but are probably r ... | 2009 | 18384407 | 
| photodynamic therapy as adjunct to non-surgical periodontal treatment in patients on periodontal maintenance: a randomized controlled clinical trial. | recent preclinical and clinical data have suggested the potential benefit of photodynamic therapy (pdt) in the treatment of periodontitis. however, currently, there are very limited data from controlled clinical trials evaluating the effect of pdt in the treatment of periodontitis. the aim of the present study was to evaluate the clinical and microbiological effects of the adjunctive use of pdt in non-surgical periodontal treatment in patients receiving supportive periodontal therapy. twenty-fou ... | 2009 | 18465191 | 
| bacterial colonization of oral implants from nondental sources. | implants showing signs of peri-implantitis harbor a microbiota similar to that of periodontitis-affected teeth. this case report describes the subgingival microbiota of a 45-year-old female with advanced periodontitis before and after complete edentulation and reconstruction with dental implants. a 3-month healing period post extraction passed before implants were placed using a two-stage submerged implant protocol. at 4- to 6-month recall visits after definitive prosthetic reconstruction, some ... | 2009 | 18657153 | 
| a case of brain abscess extended from deep fascial space infection. | a case of brain abscess in the temporal lobe caused by direct intracranial extension of deep neck abscess is described. the abscess also spread to the orbital cavity through infraorbital fissure. the possible etiology of this case might be dental surgery. the diagnostic imaging clearly showed the routes of intracranial and -orbital extension of parapharyngeal and masticator space abscesses. from the abscess specimens, oral streptococci, anaerobic streptococci, and anaerobic gram-negative bacilli ... | 2009 | 19716487 | 
| comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray. | this study compared the subgingival microbiota of subjects with refractory periodontitis (rp) to those in subjects with treatable periodontitis (grs = good responders) or periodontal health (ph) using the human oral microbe identification microarray (homim). | 2009 | 19722792 | 
| antibiotic-resistant obligate anaerobes during exacerbations of cystic fibrosis patients. | pseudomonas aeruginosa and staphylococcus aureus are thought to cause the majority of lung infections in patients with cystic fibrosis (cf). however, other bacterial pathogens may contribute to the pathophysiology of lung disease. here, obligate anaerobes were identified in a cross-sectional study, and cell numbers and antibiotic susceptibilities of facultative and obligate anaerobes from 114 sputum samples from nine children and 36 adults with cf were determined. furthermore, in 12 cf patients, ... | 2009 | 19196263 | 
| spondylodiscitis due to peptostreptococcus spp: a case report. | 2009 | 19022696 | |
| anti-biofilm properties of satureja hortensis l. essential oil against periodontal pathogens. | essential oils of several plants are widely used in ethnomedicine for their antimicrobial and anti-inflammatory properties. however, very limited data exist on their use in connection to periodontal diseases. the aim of the present study was to investigate the bacterial growth inhibiting and anti-biofilm effects of satureja hortensis l. (summer savory), salvia fruticosa m. (sage), lavandula stoechas l. (lavender), myrtus communis l., and juniperus communis l. (juniper) essential oils. chemical c ... | 2009 | 19285147 | 
| [diabetic foot infections. prevalence and antibiotic sensitivity of the causative microorganisms]. | foot infections are a common reason for hospitalization and a cause of complications in patients with diabetes. the aim of this study was to determine the prevalence of microorganisms found on culture in complicated diabetic foot infections in hospitalized patients, and the sensitivity of the causative microorganisms to antimicrobial agents. | 2009 | 19237227 | 
| bacterial diversity in persistent periapical lesions on root-filled teeth. | the purpose of this study was to analyze the bacterial diversity in persistent apical lesions on root-filled teeth by using culture-independent molecular methods. | 2009 | 21523213 | 
| descending necrotizing soft tissue infection of periodontal origin. | descending necrotizing soft tissue infections involving the neck and chest are a rare but hazardous sequela of periodontal infections. these infections are associated with significant mortality.the high mortality rates of this condition are attributed to significant delays in diagnosis and treatment of common periodontal infections that have progressed to severe disease without overt clinical signs or symptoms. as with all necrotizing soft tissue infections, making a timely diagnosis requires th ... | 2009 | 19546678 | 
| comparative evaluation of the antimicrobial efficacy of aloe vera tooth gel and two popular commercial toothpastes: an in vitro study. | aloe vera (aloe barbadensis miller) has been suggested for a wide variety of ailments but its use in dentistry is limited. this article reviews the uses of the plant and describes an in vitro investigation that compared the antimicrobial effectiveness of aloe vera tooth gel with two popular, commercially available dentifrices. the preliminary results showed that aloe vera tooth gel and the toothpastes were equally effective against candida albicans, streptococcus mutans, lactobacillus acidophilu ... | 2009 | 19819812 | 
| crystal structure of a mucus-binding protein repeat reveals an unexpected functional immunoglobulin binding activity. | lactobacillus reuteri mucus-binding protein (mub) is a cell-surface protein that is involved in bacterial interaction with mucus and colonization of the digestive tract. the 353-kda mature protein is representative of a broadly important class of adhesins that have remained relatively poorly characterized due to their large size and highly modular nature. mub contains two different types of repeats (mub1 and mub2) present in six and eight copies, respectively, and shown to be responsible for the ... | 2009 | 19758995 | 
| postoperative mediastinitis due to finegoldia magna with negative blood cultures. | we report a case of finegoldia magna (formerly known as peptostreptococcus magnus) mediastinitis following coronary artery bypass in a 50-year-old patient. even if staphylococci remain the main causative organism of postoperative mediastinitis, the responsibility of anaerobic bacteria must be considered in cases of fever and sternal drainage with negative blood cultures. | 2009 | 19812272 | 
| abdominal pain after endoscopic hemostasis of gastric tumor bleeding. splenic infarction with abscess formation. | 2009 | 19799837 | |
| cytoprotective effect of proanthocyanidin-rich cranberry fraction against bacterial cell wall-mediated toxicity in macrophages and epithelial cells. | recent studies brought evidence regarding the potential beneficial effects of cranberry polyphenols for periodontal infections. in this study, we evaluated the capacity of a proanthocyanidin-rich cranberry fraction to protect macrophages and oral epithelial cells against cytotoxicity induced by bacterial components. u937 cells, differentiated into adherent macrophage-like cells, as well as oral epithelial cells were treated with cell wall or lipopolysaccharide preparations from periodontopathoge ... | 2009 | 19277973 | 
| grafting of protein l-binding activity onto recombinant antibody fragments. | recombinant antibody fragments consisting of variable domains can be easily produced in various host cells, but there is no universal system that can be used to purify and detect them in the free form or complexed with their antigen. protein l (ppl) is a cell wall protein isolated from peptostreptococcus magnus, which has been reported to interact with the v-kappa chain of some, but not all, antibodies. here we grafted the v-kappa framework region 1 (fr1) sequence of a high-affinity ppl-binding ... | 2009 | 19268418 | 
| sudden onset proptosis secondary to cavernous sinus thrombosis from underlying mandibular dental infection. | the present report concerns a patient who presented with a 4-day history of left-sided facial pain arising from a pre-existing dental infection and progressive shortness of breath. the patient had a previous diagnosis of rheumatoid arthritis and was being treated with methotrexate. the rapid development of a right eye proptosis necessitated urgent decompression with a lateral canthotomy and cantholysis. imaging revealed a left facial abscess, cavernous sinus thrombosis (cst), bilateral internal ... | 2009 | 21789100 | 
| deep neck abscess: an analysis of microbial etiology and the effectiveness of antibiotics. | the objective was to demonstrate the aerobic and anaerobic microbiology of deep neck space abscess and to analyze the coverage rate of different empiric antimicrobial agents. a retrospective review of hospitalized patients with deep neck abscess diagnosed at a tertiary-care, general hospital between april 2001 and october 2006. the study enrolled 100 patients. the bacterial cultures of 89 patients yielded positive results (89%). the predominant aerobes were viridans streptococci, klebsiella pneu ... | 2008 | 21694873 | 
| bisphosphonate-associated osteonecrosis: a clinician's reference to patient management. | bisphosphonates (bps), as inhibitors of osteoclasts, are widely used in the management of metastatic bone disease and in the prevention of osteomalacia and osteoporosis. recent cases of bone necrosis of the jaws have been associated with the use of bisphosphonate therapy. a case is presented of a patient with osteonecrosis of the maxilla with a history of long-term bisphosphonate therapy for metastatic breast cancer. the authors treated the patient and suggest appropriate patient management guid ... | 2008 | 18767452 | 
| detection of anaerobic prosthetic joint infection by pcr and dna sequencing--a case report. | 2008 | 18766493 | |
| rationally designed ligands for use in affinity chromatography: an artificial protein l. | synthetic affinity ligands can circumvent the drawbacks of natural immunoglobulin (ig)-binding proteins by imparting resistance to chemical and biochemical degradation and to in situ sterilization, as well as ease and low cost of production. protein l (ppl), isolated from peptostreptococcus magnus strains, interacts with the fab (antigen-binding fragment) portion of igs, specifically with kappa light chains, and represents an almost universal ligand for the purification of antibodies. the concep ... | 2008 | 18826050 | 
| difficult intubation provokes bacteremia. | to evaluate the prevalence of bacteremia after mask ventilation, laryngoscopy, and endotracheal intubation before induction of general anesthesia and to discover any correlation between traumatic manipulations and bacteremia. the specific bacteria responsible, knowledge of which may guide the prophylactic use of antibiotics, also were investigated. | 2008 | 18983229 | 
| tongue biofilm areal density and tongue coating index. | two methods have been employed to measure the amount of tongue biofilm in humans: (1) areal density of microbes (cfu cm(-2)) (tongue scrape from a known/measured area), or (2) a tongue-coating index, where a human judge assesses the amount of 'coating' by visual inspection. the two methods were compared, both on human volunteers and on artificial biofilms. fusobacterium nucleatum (fn), prevotella intermedia (pi), streptococcus mutans (sm) and peptostreptococcus micros (pm) were obtained from sto ... | 2008 | 21386152 | 
| alternate arrangement of ppl b3 domain and spa d domain creates synergistic double-site binding to vh3 and vkappa regions of fab. | in our previous study, a kind of novel hybrid immunoglobulin (ig)-binding proteins (ibps) was obtained with the characteristic structure of alternately arranged finegoldia magna (formerly peptostreptococcus magnus) protein l (p. magnus protein l, ppl) b3 domain (b3) and staphylococcal protein a (spa) d domain (d). in this study, two representative molecules of these novel proteins, ld3 (b3-d-b3) and ld5 (b3-d-b3-d-b3) (ld3/5), showed substantially higher affinity for igg-f(ab')2, igm, and iga th ... | 2008 | 18694300 | 
| value of anaerobic culture in bacterial surveillance program for platelet concentrates. | short-term aerobic bacterial culture (stabc) has been used routinely in hong kong since 1998 to reduce bacterial contamination in platelet concentrates (pcs) with good results. with more countries implementing routine aerobic and anaerobic cultures of pcs, a prospective study was conducted to determine the value of anaerobic culture to stabc. | 2008 | 18694462 | 
| evolutional selection of a combinatorial phage library displaying randomly-rearranged various single domains of immunoglobulin (ig)-binding proteins (ibps) with four kinds of ig molecules. | protein a, protein g and protein l are three well-defined immunoglobulin (ig)-binding proteins (ibps), which show affinity for specific sites on ig of mammalian hosts. although the precise functions of these molecules are not fully understood, it is thought that they play an important role in pathogenicity of bacteria. the single domains of protein a, protein g and protein l were all demonstrated to have function to bind to ig. whether combinations of ig-binding domains of various ibps could exh ... | 2008 | 18700046 | 
| clinicopathologic challenge. gangrenous cellulitis caused by peptostreptococcus. | 2008 | 18717855 | |
| the influence of mineral trioxide aggregate on adaptive immune responses to endodontic pathogens in mice. | this study assessed the influence of mineral trioxide aggregate (mta) on adaptive immune responses. balb/c mice were immunized with heat-killed fusobacterium nucleatum (fn) in mta or other control adjuvants, and serum igg responses to fn were measured. either fn- or peptostreptococcus anaerobius (pa)-reactive memory t cells (tm) were preincubated in vitro with/without mta and restimulated with fn or pa. tm proliferation and cytokine production were assessed. compared with control groups, immunog ... | 2008 | 18718367 | 
| root canal microbiota of teeth with chronic apical periodontitis. | samples from infected root canals of 43 teeth with chronic apical periodontitis were analyzed for the presence and relative levels of 83 oral bacterial species and/or phylotypes using a reverse-capture checkerboard hybridization assay. associations between the most frequently detected taxa were also recorded. the most prevalent taxa were olsenella uli (74%), eikenella corrodens (63%), porphyromonas endodontalis (56%), peptostreptococcus anaerobius (54%), and bacteroidetes oral clone x083 (51%). ... | 2008 | 18768651 | 
| [peptostreptococcus endocarditis: presentation of two cases and literature review]. | we describe two new cases of peptostreptococcus endocarditis, one case of peptostreptococcus micros prosthetic valve endocarditis and the other of peptostreptococcus assaccharolyticus tricuspid native valve endocarditis in an intravenous drug user (idu) patient and review nine cases previously reported. | 2008 | 18769744 | 
| photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial. | recent preclinical and clinical data have suggested a potential benefit of photodynamic therapy (pdt) in the treatment of periodontitis. however, there are very limited data from controlled clinical trials evaluating the effect of pdt in the treatment of periodontitis. the aim of this study was to evaluate the clinical and microbiologic effects of the adjunctive use of pdt to non-surgical periodontal treatment. | 2008 | 18771363 | 
| campylobacter species isolated from extra-oro-intestinal abscesses: a report of four cases and literature review. | campylobacter species are frequently isolated from fecal specimens of patients with diarrheal illness. several campylobacter species are commonly isolated from the oral cavity. in contrast, campylobacter species are rarely isolated from extra-oro-intestinal abscesses. reported here are four cases of extra-oro-intestinal abscesses due to polymicrobial flora, including campylobacter species. the first case is a 35-year-old woman who was diagnosed with a brain abscess caused by c. gracilis, strepto ... | 2008 | 18488257 | 
| changes in abundance of lactobacillus spp. and streptococcus suis in the stomach, jejunum and ileum of piglets after weaning. | this present study investigated the changes in bacterial community composition, with an emphasis on lactobacillus spp. and streptococcus suis populations as potentially beneficial and harmful groups, in the stomach, jejunum and ileum of piglets after weaning (21 days postpartum) by 16s rrna gene-based methods. denaturing gradient gel electrophoresis analysis showed that, after weaning, predominant bands related to lactobacillus spp. disappeared and were replaced by potential pathogenic species, ... | 2008 | 18554303 | 
| influence of local tetracycline on the microbiota of alveolar osteitis in rats. | the aim of the present study was to evaluate the effects of local tetracycline on the occurrence of alveolar osteitis in rats, and on the microbiota associated to this infection. forty wistar rats were randomly assigned to 4 groups (n=10): i - the rats had the maxillary right incisor extracted and the alveolar wound did not receive any treatment; ii - adrenaline and ringer-pras were introduced into the alveolar wound; iii - the alveolar wound was irrigated with sterile saline; and iv - the alveo ... | 2008 | 18568225 | 
| quantitative survival of aerobic and anaerobic microorganisms in port-a-cul and copan transport systems. | transport media should preserve the viability and stability of microorganisms in clinical specimens. in this study, the port-a-cul transport system and the copan transport system without charcoal, both designed to preserve anaerobes, were evaluated. dacron swabs were inoculated with two combinations of facultative and anaerobic organisms typically found in vaginal swab samples. combination i contained candida albicans, escherichia coli, enterococcus spp., group b streptococci, lactobacillus cris ... | 2008 | 18579722 | 
| deep brain stimulation for holmes' tremor related to a thalamic abscess. | medical treatment is usually ineffective for holmes' tremor, and surgery is the treatment of choice for many patients. here we report the case of a 14-year-old girl who developed holmes' tremor related to a thalamic abscess and was successfully treated with thalamic deep brain stimulation. | 2008 | 18581123 | 
| relationship of specific vaginal bacteria and bacterial vaginosis treatment failure in women who have sex with women. | bacterial vaginosis frequently persists after treatment. the role of newly defined bacterial vaginosis-associated bacteria (bvab), which have a specificity for this condition of 97% or greater, has not been assessed. | 2008 | 18591634 | 
| a case of necrotizing fasciitis due to streptococcus agalactiae, arcanobacterium haemolyticum, and finegoldia magna in a dog-bitten patient with diabetes. | we report a case of necrotizing fasciitis involving streptococcus agalactiae, arcanobacterium haemolyticum, and finegoldia magna in a 36-yr-old female diabetic patient, which started after a minor dog bite to the toe of the patient. this case suggested that a trivial infection after a minor dog bite in an immunocompromised patient such as diabetes patient could result in a significant complication such as necrotizing fasciitis. the life-threatening infection was cured by timely above-the-knee am ... | 2008 | 18594170 | 
| increasing trends in antimicrobial resistance among clinically important anaerobes and bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. | this study reports data on the susceptibilities to five commonly used antianaerobic agents of five clinically frequently encountered anaerobes from 2000 to 2007 and to bacteroides fragilis isolates causing nosocomial infections from 1990 to 2006. there was a trend of decreasing susceptibilities of these anaerobes to ampicillin-sulbactam, cefmetazole, chloramphenicol, and clindamycin with time during the study period. the rates of susceptibility to clindamycin and cefmetazole for all clinical iso ... | 2008 | 18625771 | 
| formulation and evaluation of pla and plga in situ implants containing secnidazole and/or doxycycline for treatment of periodontitis. | the purpose of this study is to formulate in situ implants containing doxycycline hydrochloride and/or secnidazole that could be used in the treatment of periodontitis by direct periodontal intrapocket administration. biodegradable polymers [poly (lactide) (pla) and poly (lactide-co-glycolide) (plga)], each polymer in two concentrations 25%w/w, 35%w/w were used to formulate the in situ implants. the rheological behavior, in vitro drug release and the antimicrobial activity of the prepared implan ... | 2008 | 18654864 | 
| characterization of the protein unfolding processes induced by urea and temperature. | correct folding is critical for the biological activities of proteins. as a contribution to a better understanding of the protein (un)folding problem, we studied the effect of temperature and of urea on peptostreptococcal protein l destructuration. we performed standard molecular dynamics simulations at 300 k, 350 k, 400 k, and 480 k, both in 10 m urea and in water. protein l followed at least two alternative unfolding pathways. urea caused the loss of secondary structure acting preferentially o ... | 2008 | 18065481 | 
| microbiology and management of joint and bone infections due to anaerobic bacteria. | to describes the microbiology, diagnosis, and management of septic arthritis and osteomyelitis due to anaerobic bacteria. | 2008 | 18392922 | 
| ocular infections due to anaerobic bacteria in children. | the recent increased recovery of anaerobic bacteria from children has led to greater appreciation of the role these organisms play in pediatric infections at all body sites, including the eye. in studies that employed adequate methods for recovery of anaerobes, they were isolated from approximately one-third of the children with conjunctivitis, half of the time in pure culture. the predominant recovered anaerobes were clostridium spp., gram-negative anaerobic bacilli, and peptostreptococcus spp. ... | 2008 | 18404954 | 
| [microbiological and biochemical characteristics of inflammatory tissues in the periodontium]. | to investigate bacterial populations in subgingival and supragingival plaque samples of patients with inflammatory periodontal diseases and activities of the lysosomal enzymes--lysozyme, alkaline phosphatase, and beta-glucuronidase--in peripheral venous blood, in gingival crevicular fluid, and mixed nonstimulated saliva. | 2008 | 18413987 | 
| infection associated with hematoma formation after shoulder arthroplasty. | hematoma formation requiring operative treatment after shoulder arthroplasty may be associated with higher patient morbidity. we therefore determined whether there was an association of hematoma formation requiring operative treatment with deep infection after shoulder arthroplasty. between 1978 and 2006, we performed 4147 shoulder arthroplasties in 3643 patients. of these, 12 shoulders (0.3%) underwent reoperation for hematoma formation. the mean time interval from arthroplasty to surgery for t ... | 2008 | 18421541 | 
| microbial analysis of canals of root-filled teeth with periapical lesions using polymerase chain reaction. | the objective of the present study was to investigate the presence of nine bacterial species in root-filled teeth associated with periapical lesions using a polymerase chain reaction analysis and to correlate these species with clinical features of the cases. dna was extracted from 45 canal samples of root-filled teeth with periapical lesions. a pcr assay using species-specific primers of 16s rdna and the downstream intergenic spacer region was used for microbial detection. enterococcus faecalis ... | 2008 | 18436030 | 
| characterization of chorioamnionitis in 2nd-trimester c-section placentas and correlation with microorganism recovery from subamniotic tissues. | prolonged exposure to infection appears to influence fetal/neonatal development. we characterize the relationship between histologic patterns of inflammation and microorganism recovery from the placentas of live born infants delivered before the 28th postmenstrual week. the subamniotic parenchyma of 835 placentas delivered by cesarean section were cultured and evaluated for specific histologic patterns of inflammation in a blinded fashion. cases with prolonged membrane rupture were excluded. mic ... | 2008 | 18237241 | 
| complete genome sequence of finegoldia magna, an anaerobic opportunistic pathogen. | finegoldia magna (formerly peptostreptococcus magnus), a member of the gram-positive anaerobic cocci (gpac), is a commensal bacterium colonizing human skin and mucous membranes. moreover, it is also recognized as an opportunistic pathogen responsible for various infectious diseases. here, we report the complete genome sequence of f. magna atcc 29328. the genome consists of a 1,797,577 bp circular chromosome and an 189,163 bp plasmid (ppep1). the metabolic maps constructed based on the genome inf ... | 2008 | 18263572 | 
| smap29 congeners demonstrate activity against oral bacteria and reduced toxicity against oral keratinocytes. | cathelicidins are antimicrobial peptides found in epithelial and mucosal tissues as well as the secondary granules of neutrophils. smap29, a sheep cathelicidin, has differential antimicrobial properties against various pathogens, including periodontal organisms. the purpose of this study was to evaluate the antimicrobial properties and cytotoxicity of smap29, smap28, and three congeners (smap18a, smap18d, and smap14a). | 2008 | 18279175 | 
| microbiology and management of abdominal infections. | this review describes the microbiology, diagnosis, and management of intra-abdominal infections. these infections include secondary peritonitis, abdominal abscesses, and cholangitis. the infection generally occurs because enteric microorganisms enter the peritoneal cavity through a defect in the wall of the intestine or other viscus as a result of obstruction, infarction, or direct trauma. mixed aerobic and anaerobic flora can be recovered. the predominant aerobic isolates are escherichia coli, ... | 2008 | 18288616 | 
| isolation of obligate anaerobic bacteria from ulcerative keratitis in domestic animals. | to determine the frequency of obligate anaerobic bacterial isolation from corneal samples of domestic animals with ulcerative keratitis and to characterize the historical, clinical, cytological, and microbiological features of culture-positive cases. | 2008 | 18302576 | 
| [relationship between clostridium difficile associated diarrhea and intestinal microecosystem disorder in patients received allogeneic hematopoietic stem cell transplantation]. | this study was to investigate the relationship between clostridium difficile associated diarrhea (cdad) and intestinal microecosystem in patients received allogeneic hematopoietic stem cell transplantation (allo-hsct) and to clarify clinical characteristics of intestinal microecosystem disorder. clostridium difficile (cd) was isolated and identified by enzyme-linked-immunosorbent assay using clostridium difficile premier toxins a&b kit and anaerobic culture in 44 cases with diarrhea. fecal flora ... | 2008 | 18315917 | 
| urea and guanidinium chloride denature protein l in different ways in molecular dynamics simulations. | in performing protein-denaturation experiments, it is common to employ different kinds of denaturants interchangeably. we make use of molecular dynamics simulations of protein l in water, in urea, and in guanidinium chloride (gdmcl) to ascertain if there are any structural differences in the associated unfolding processes. the simulation of proteins in solutions of gdmcl is complicated by the large number of charges involved, making it difficult to set up a realistic force field. furthermore, at ... | 2008 | 18339753 | 
| moraxella catarrhalis-dependent tonsillar b cell activation does not lead to apoptosis but to vigorous proliferation resulting in nonspecific igm production. | the respiratory pathogen moraxella catarrhalis has a high affinity for human igd and is mitogenic for peripheral blood b lymphocytes. moraxella igd-binding protein, which is a multifunctional outer membrane protein with adhesive properties, is responsible for the interaction. previous experiments with the ig-binding b cell superantigens protein a and protein l from staphylococcus aureus and peptostreptococcus magnus, respectively, have suggested that nonimmune bcr cross-linking induces b cell ap ... | 2008 | 18372337 | 
| [lumbar pyomyositis caused by finegoldia magna (peptostreptococcus magnus) in a patient with hepatitis c virus infection]. | 2008 | 18373916 | |
| a retrospective analysis of isolates from patients with vaginitis in a private greek obstetric/gynecological hospital (2003-2006). | vaginitis is a common cause of complaints in women in various parts of the world. through our literature search, we identified noteworthy differences in the etiology of vaginitis based on the geographic location. this study was conducted to describe microbial etiology in a population of symptomatic women with vaginitis in greece. | 2008 | 18376352 | 
| purification and partial characterization of a bacteriocin produced by eikenella corrodens. | the purpose of this study was to purify and characterize a bacteriocin produced by eikenella corrodens a32e2. | 2008 | 17922820 | 
| in vitro and in vivo antibacterial activities of dc-159a, a new fluoroquinolone. | dc-159a is a new 8-methoxy fluoroquinolone that possesses a broad spectrum of antibacterial activity, with extended activity against gram-positive pathogens, especially streptococci and staphylococci from patients with community-acquired infections. dc-159a showed activity against streptococcus spp. (mic(90), 0.12 microg/ml) and inhibited the growth of 90% of levofloxacin-intermediate and -resistant strains at 1 microg/ml. the mic 90s of dc-159a against staphylococcus spp. were 0.5 microg/ml or ... | 2008 | 17938194 | 
| actinomycetemcomitin: a new bacteriocin produced by aggregatibacter (actinobacillus) actinomycetemcomitans. | aggregatibacter (actinobacillus) actinomycetemcomitans p(7-20) strain isolated from a periodontally diseased patient has produced a bacteriocin (named as actinomycetemcomitin) that is active against peptostreptococcus anaerobius atcc 27337. actinomycetemcomitin was produced during exponential and stationary growth phases, and its amount decreased until it disappeared during the decline growth phase. it was purified by ammonium sulphate precipitation (30-60% saturation), and further by fplc (mono ... | 2008 | 17990016 | 
| severe versus local odontogenic bacterial infections: comparison of microbial isolates. | it was the aim of this study to evaluate the clinical and microbiological differences between severe and local odontogenic abscesses. | 2008 | 17998782 | 
| the bacteriology and antimicrobial susceptibility of infected and non-infected dog bite wounds: fifty cases. | dog bite wounds are a common reason for dogs requiring veterinary care, but there is surprisingly little data on the bacteriology of bite wounds. a prospective study was performed on dogs with various grades of bite wound to identify the bacteria present in these wounds. swabs were collected from all wounds for bacterial culture and cytology. all swabs were cultured aerobically and anaerobically and all aerobic cultures were evaluated for antibiotic susceptibility using the kirby bauer disk diff ... | 2008 | 18029118 | 
| generation and expression of a minimal hybrid ig-receptor formed between single domains from proteins l and g. | the ig-binding properties of protein l from peptostreptococcus magnus and protein g from streptococcus have been successfully combined through the construction of a novel hybrid protein, consisting of a single ig-binding domain from each protein. the biophysical and biochemical properties of this construct have been characterized through equilibrium and pre-equilibrium fluorescence spectroscopy, circular dichroism, isothermal titration calorimetry, affinity chromatography, and conformational sta ... | 2008 | 18158250 | 
| european surveillance study on antimicrobial susceptibility of gram-positive anaerobic cocci. | gram-positive anaerobic cocci (gpac) are a heterogeneous group of microorganisms frequently isolated from local and systemic infections. in this study, the antimicrobial susceptibilities of clinical strains isolated in 10 european countries were investigated. after identification of 299 gpac to species level, the minimum inhibitory concentrations of penicillin, imipenem, clindamycin, metronidazole, vancomycin and linezolid were determined by the agar dilution method according to the clinical and ... | 2008 | 18180149 | 
| detection and identification of bacterial dna in semen. | to detect and identify bacteria in semen by sequencing polymerase chain reaction (pcr)-amplified ribosomal rna gene regions (rdnas). | 2008 | 18191853 | 
| descending necrotizing mediastinitis secondary to retropharyngeal abscess without cervical spread. | cervical infections can cause neck phlegmonosa and occasionally develop lethal mediastinitis. we report a 52-year-old man with a retropharyngeal abscess causing descending mediastinis without cervical spread. thoracoscopic drainage without cervicotomy was successful. deep neck infections causing a descending mediastinitis should be considered in patients even without an abnormal neck appearance. | 2008 | 18213468 |