Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [phenotypic detection of carbapenemase associated with extended-spectrum beta-lactamase in klebsiella pneumoniae]. | 2011 | 22154523 | |
| Effects of arsenite stress on growth and proteome of Klebsiella pneumoniae. | In the present study an arsenite, As(III), tolerating bacterium, MR4, was isolated from Mulla River Pune, India, capable of reducing arsenate to arsenite and identified as Klebsiella pneumoniae (HQ857583). Comparative proteomic analysis using two-dimensional gel electrophoresis (2-DGE) and matrix assisted laser desorption ionization-time of flight-time of flight (MALDI-TOF/TOF) was used to monitor the proteins undergoing changes in expression levels under 2.5mM As(III) stress. The 2-DGE proteome ... | 2011 | 22209886 |
| the rising problem of antimicrobial resistance in the intensive care unit. | abstract: mainly due to its extremely vulnerable population of critically ill patients, and the high use of (invasive) procedures, the intensive care unit (icu) is the epicenter of infections. these infections are associated with an important rise in morbidity, mortality, and healthcare costs. the additional problem of multidrug-resistant pathogens boosts the adverse impact of infections in icus. several factors influence the rapid spread of multidrug-resistant pathogens in the icu, e.g., new mu ... | 2011 | 22112929 |
| prevalence of plasmid-mediated quinolone resistance and its association with extended-spectrum beta-lactamase and ampc beta-lactamase in enterobacteriaceae. | we investigated the prevalence of plasmid-mediated quinolone resistance and its association with extended-spectrum beta-lactamase (esbl) and ampc beta-lactamase in enterobacteriaceae. | 2011 | 22016679 |
| Gut microbiota of healthy and malnourished children in bangladesh. | Poor health and malnutrition in preschool children are longstanding problems in Bangladesh. Gut microbiota plays a tremendous role in nutrient absorption and determining the state of health. In this study, metagenomic tool was employed to assess the gut microbiota composition of healthy and malnourished children. DNA was extracted from fecal samples of seven healthy and seven malnourished children (n?=?14; age 2-3?years) were analyzed for the variable region of 16S rRNA genes by universal primer ... | 2011 | 22125551 |
| International Nosocomial Infection Control Consortium (INICC) report, data summary of 36 countries, for 2004-2009. | The results of a surveillance study conducted by the International Nosocomial Infection Control Consortium (INICC) from January 2004 through December 2009 in 422 intensive care units (ICUs) of 36 countries in Latin America, Asia, Africa, and Europe are reported. During the 6-year study period, using Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN; formerly the National Nosocomial Infection Surveillance system [NNIS]) definitions for device-associated hea ... | 2011 | 21908073 |
| Studies on antimicrobial activities of solvent extracts of different spices. | The antimicrobial activities of the ethyl acetate, acetone and methanol extract of 12 plant species were studied. The extract of Capsicum annuum (red pepper) (fruit) Zingiber officinale (ginger) (root), Cuminum cyminum (cumin), Alpinia ficinarum (galingale), Coriandrum sativum (coriander), Cinnamomun zeylanicum Nees (cinnamomun), Origanum onites L. (thyme), Folium sennae (senna), Eugenia caryophyllata (cloves), Flos tiliae (lime), Folium menthae crispae (peppermint) and Piper nigrum (blackpepper ... | 2011 | 21882663 |
| Biological activity of carbazole alkaloids and essential oil of Murraya koenigii against antibiotic resistant microbes and cancer cell lines. | A total of three carbazole alkaloids and essential oil from the leaves of Murraya koenigii (Rutaceae) were obtained and examined for their effects on the growth of five antibiotic resistant pathogenic bacteria and three tumor cell lines (MCF-7, P 388 and Hela). The structures of these carbazoles were elucidated based on spectroscopy data and compared with literature data, hence, were identified as mahanine (1), mahanimbicine (2) and mahanimbine (3). The chemical constituents of the essential oil ... | 2011 | 22105714 |
| synthesis and characterization of the antibacterial potential of zno nanoparticles against extended-spectrum β-lactamases-producing escherichia coli and klebsiella pneumoniae isolated from a tertiary care hospital of north india. | the reemergence of infectious diseases and the continuous development of multidrug resistance among a variety of disease-causing bacteria in clinical setting pose a serious threat to public health worldwide. extended-spectrum β-lactamases (esbls) that mediate resistance to third-generation cephalosporin are now observed all over the world in all species of enterobacteriaceae, especially escherichia coli and klebsiella pneumoniae. in this work, zno nanoparticles (nps) were synthesized by the sol- ... | 2011 | 22159886 |
| prevalence of extended-spectrum β-lactamase-producing escherichia coli and klebsiella pneumoniae in food-producing animals. | to evaluate the diversity of extended-spectrum β-lactamases (esbl) genes among food-producing animals, 48 isolates of esbl-producing escherichia coli isolates were obtained from rectal samples of broilers, layers, beef cattle and pigs, at the slaughterhouse level. esbl-carrying e. coli were isolated from 60.0% of individual broiler rectal samples, 5.9% of layers, 12.5% of beef cattle and 3% of pigs. one esbl-producing klebsiella pneumoniae was isolated from a broiler. the esbl-positive e. coli i ... | 2011 | 21979457 |
| molecular dissection of an outbreak of carbapenem-resistant enterobacteriaceae reveals intergenus kpc carbapenemase transmission through a promiscuous plasmid. | carbapenem-resistant enterobacteriaceae (cre) have emerged as major causes of health care-associated infections worldwide. this diverse collection of organisms with various resistance mechanisms is associated with increased lengths of hospitalization, costs of care, morbidity, and mortality. the global spread of cre has largely been attributed to dissemination of a dominant strain of klebsiella pneumoniae producing a serine β-lactamase, termed k. pneumoniae carbapenemase (kpc). here we report an ... | 2011 | 22045989 |
| molecular basis of ndm-1, a new antibiotic resistance determinant. | the new delhi metallo-β-lactamase (ndm-1) was first reported in 2009 in a swedish patient. a recent study reported that klebsiella pneumonia ndm-1 positive strain or escherichia coli ndm-1 positive strain was highly resistant to all antibiotics tested except tigecycline and colistin. these can no longer be relied on to treat infections and therefore, ndm-1 now becomes potentially a major global health threat.in this study, we performed modeling studies to obtain its 3d structure and ndm-1/antibi ... | 2011 | 21887283 |
| [the first experience of application of pcr techniques in real-time mode to diagnose bacteriemia during postoperational period in cardiosurgery patients]. | the results comparison is made between pcr polymerase chain reaction techniques in real-time mode and cultural techniques of analysis of blood samples in patients with suspicion of bacteriemia during early postoperational period. from september to december 2009 43 blood samples from 37 adult patients aged 59+9.2 years were analyzed on suspicion of bacteriemia. the blood samples for pcr analysis (septifast technique roche diagnostics, switzerland) were taken parallel to the inoculation. among 43 ... | 2011 | 22164420 |
| Outcomes and characteristics of ertapenem-nonsusceptible Klebsiella pneumoniae bacteremia at a university hospital in Northern Taiwan: A matched case-control study. | BACKGROUND AND PURPOSE: Carbapenem-resistant Klebsiella pneumoniae is an emerging problem worldwide. The object of this study was to investigate the risk factors, characteristics and outcomes of ertapenem-nonsusceptible K pneumoniae (ENSKp) bacteremia. METHODS: We conducted a 1:2 ratio matched case-control study. The controls were randomly selected among patients with ertapenem-susceptible K pneumoniae (ESKp) bacteremia and were matched with ENSKp cases for bacteremia. RESULTS: Seventy-five pati ... | 2011 | 22154994 |
| urinary pathogens and drug susceptibility patterns of urinary tract infections among antenatal clinic attendees in ibadan, nigeria. | aim: to determine the bacterial agents involved in urinary tract infections in pregnant women and their antibiotic susceptibility patterns in ibadan, nigeria. methods: all consenting subjects who attended antenatal clinics of the university college hospital and adeoyo maternity hospital, ibadan, nigeria, from 1 april 2007 and 30 march 2009 were interviewed to obtain demographic and pregnancy health data. mid-stream urine samples obtained were processed by standard methods. confirmed bacterial ... | 2011 | 21917070 |
| Impact of adopting minimum inhibitory concentration as the determinant of susceptibility to cephalosporins and carbapenems in multi-drug resistant Enterobacteriaceae. | The Clinical and Laboratory Standards Institute has recommended that Enterobacteriaceae susceptibility to most cephalosporins and carbapenems be reported according to minimum inhibitory concentration (MIC) alone. We analyzed our record of multi-drug resistant Enterobacteriaceae to assess the impact of these changes. We compared susceptibilities of ceftriaxone-resistant Enterobacteriaceae when using the 2009 and new 2010 MIC standards. Vitek2® (BioMerieux), was used to assess the changes in susce ... | 2011 | 21912922 |
| Improved antimicrobial efficacy with nitric oxide releasing nanoparticle generated S-nitrosoglutathione. | Nitric oxide (NO) plays a vital role in mammalian host defense through a variety of mechanisms. In particular, NO can oxidize to form reactive nitrogen species or interact with protein thiols and metal centers, blocking essential microbial processes. S-nitrosoglutathione (GSNO), a potent NO donor formed by the interaction of NO with intracellular glutathione (GSH), is a major factor in this pathway and is considered one of the strongest naturally occurring nitrosating agent. We previously descri ... | 2011 | 21946032 |
| prevention of infections associated with combat-related extremity injuries. | during combat operations, extremities continue to be the most common sites of injury with associated high rates of infectious complications. overall, ∼ 15% of patients with extremity injuries develop osteomyelitis, and ∼ 17% of those infections relapse or recur. the bacteria infecting these wounds have included multidrug-resistant bacteria such as acinetobacter baumannii, pseudomonas aeruginosa, extended-spectrum β-lactamase-producing klebsiella species and escherichia coli, and methicillin-resi ... | 2011 | 21814090 |
| polyclonal antibody against conserved sequences of mce1a protein blocks mtb infection in macrophages. | the pathogenesis of mycobacterium tuberculosis is largely due to its ability to enter and survive within human macrophages. it is suggested that a specific protein namely mammalian cell entry protein is involved in the pathogenesis and the specific gene for this protein mce1a has been identified in several pathogenic organisms such as rickettsia, shigella, escherichia coli, helicobacter, streptomyces, klebsiella, vibrio, neisseria, rhodococcus, nocardioides, saccharopolyspora erthyrae, and pseud ... | 2011 | 22159737 |
| [susceptibility of klebsiella oxytoca to selected antibiotics]. | fifty two clinical isolates of k. oxytoca were included. all of analysed strains were isolated from wound swabs. the aim of this study was to evaluate mic value of amoxicillin with clavulanic acid, tigecycline and ciprofloxacin. the susceptibility to amoxicillin with clavulanic acid and tigecycline was tested by the etest. the susceptibility to ciprofloxacine was tested by the agar dilution method. among of analysed k. oxytoca strains 44 (84.6%) were susceptible to tigecycline, 27 (51.9%) to amo ... | 2011 | 22184898 |
| screening of antimicrobial activity of cistus ladanifer and arbutus unedo extracts. | in this work, the in vitro antimicrobial activity of different crude extracts obtained from cistus ladanifer l. and arbutus unedo l. was investigated. the ethanol, methanol and acetone/water extracts of cistus ladanifer and arbutus unedo were prepared using different extraction methods and their antimicrobial activities against reference strains, including three gram-positive, five gram-negative and three yeasts, and against clinical isolates of helicobacter pylori and methicillin-resistant stap ... | 2011 | 22077559 |
| [homology analysis of klebsiella pneumoniae isolated from clinic and hospital environments]. | 2011 | 22172269 | |
| Epidemiology and molecular characterisation of metallo-ß-lactamase-producing Enterobacteriaceae in a university hospital Intensive Care Unit in Greece. | The molecular epidemiology of VIM-producing Enterobacteriaceae isolated at the beginning of an epidemic in the Intensive Care Unit (ICU) of a university hospital in Athens, Greece, was studied. All Gram-negative organisms isolated from March 2004 to November 2005 positive for metallo-ß-lactamase (MBL) production were submitted to polymerase chain reaction (PCR) and sequencing, to repetitive sequence-based PCR (Rep-PCR) for molecular typing, and to S1 nuclease digestion for plasmid DNA characteri ... | 2011 | 21873034 |
| Comparative effectiveness of aminoglycosides, polymyxin B, and tigecycline for clearance of carbapenem-resistant Klebsiella pneumoniae from urine. | Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an increasingly common cause of health care-associated urinary tract infections. Antimicrobials with in vitro activity against CRKP are typically limited to polymyxins, tigecycline, and often, aminoglycosides. We conducted a retrospective cohort study of cases of CRKP bacteriuria at New York-Presbyterian Hospital from January 2005 through June 2010 to compare microbiologic clearance rates based on the use of polymyxin B, tigecycline, or an ami ... | 2011 | 21968368 |
| [In vitro evaluation of bactericidal activity of an over-heated saturated dry atomized steam electro-medical device on inert contaminated surfaces]. | Surface disinfection together with cleaning practises and aseptic procedures are established measures for effective prevention of infectious diseases reducing infection risks. In this study, we evaluated the bactericidal effectiveness in vitro of the electro-medical device Sani System, an over-heated saturated dry-steam disinfection system, against predetermined bacterial load dried on inert surfaces. In particular we have tested different materials, representative of operating rooms furnishing ... | 2011 | 22026238 |
| Detection of Citrobacter koseri carrying beta-lactamase KPC-2 in a hospitalised patient, Greece, July 2011. | This report describes the detection of Citrobacter koseri carrying K. pneumoniae carbapenemase (KPC-2) isolated in July 2011 from a Greek patient, who was also colonised by a Klebsiella pneumoniae strain coproducing KPC-2 and Verona integron-encoded metallo-beta-lactamase (VIM)-1. | 2011 | 22008199 |
| [Review of the effectiveness of an empirical antibiotic therapy in suspected ventilator-associated pneumonia]. | Ventilator-associated pneumonia (VAP) occurs in approximately 10-20% of mechanically ventilated patients, and is associated with an extremely high mortality rate (up to 70%). The purpose of the study was to determine the susceptibility spectrum of Klebsiella, Pseudomonas and Acinetobacter strains isolated from VAP patients. | 2011 | 22011920 |
| Comparative study of antimicrobial activity and phytochemical analysis of methanolic and aqueous extracts of the fruit of Emblica officinalis against pathogenic bacteria. | To investigate antimicrobial potential of aqueous (infusions, decoctions) and methanlic extracts (1:2 and 1:5 concentrations) of Emblica officinalis (amla) against seven pathogenic bacteria namely Staphylococcs aureus, Staphylococcus saprophyticus, Escherichia coli, Enterococcus faecalis, Enterococcus cloacae, Proteus vulgaris and Klebsiella pneumoniae. | 2011 | 21977871 |
| The characteristics of NDM-producing Klebsiella pneumoniae from Canada. | After recent hospitalization in India (New Delhi and Mumbai), 2 patients, on their return to Canada, presented with lower urinary tract infections due to multiresistant Klebsiella pneumoniae that produced New Delhi metallo-ß-lactamase and CTX-M-15. The organisms belonged to clones ST147 and ST340, and were positive for aac(6')-Ib-cr, as well as for the ccdAB and vagCD addiction systems. The bla(NDM) plasmid was located on the IncFIIA and IncA/C replicon groups of plasmids. Clones ST147 and ST340 ... | 2011 | 21924993 |
| in vitro activity of tigecycline and comparators against gram-negative bacteria isolated from a tertiary hospital in alexandria, egypt. | the emergence of infections caused by multidrug-resistant gram-negative bacteria, in particular pseudomonas aeruginosa, acinetobacter baumannii, and klebsiella pneumoniae, has necessitated the search for alternative therapy by either introducing new agents or renewing interest in old agents. this study compares the in vitro activity of tigecycline (tig), recently introduced to egyptian market, to other potentially active antimicrobials as colistin (col), imipenem (ipm), levofloxacin (lev), and p ... | 2011 | 21875338 |
| Synthesis and antimicrobial properties of naphthylamine derivatives having a thiazolidinone moiety. | The aim of this study was to evaluate the influence of pharmacophores having naphthylamine and nitro groups on the antimicrobial (antibacterial and antifungal) activity of thiazolidinone derivatives. | 2011 | 21968886 |
| The priB gene of Klebsiella pneumoniae encodes a 104-amino acid protein that is similar in structure and function to Escherichia coli PriB. | Primosome protein PriB is a single-stranded DNA-binding protein that serves as an accessory factor for PriA helicase-catalyzed origin-independent reinitiation of DNA replication in bacteria. A recent report describes the identification of a novel PriB protein in Klebsiella pneumoniae that is significantly shorter than most sequenced PriB homologs. The K. pneumoniae PriB protein is proposed to comprise 55 amino acid residues, in contrast to E. coli PriB which comprises 104 amino acid residues and ... | 2011 | 21931731 |
| global spread of carbapenemase-producing enterobacteriaceae. | carbapenemases increasingly have been reported in enterobacteriaceae in the past 10 years. klebsiella pneumoniae carbapenemases have been reported in the united states and then worldwide, with a marked endemicity at least in the united states and greece. metallo-enzymes (verona integron-encoded metallo-β-lactamase, imp) also have been reported worldwide, with a higher prevalence in southern europe and asia. carbapenemases of the oxacillinase-48 type have been identified mostly in mediterranean a ... | 2011 | 22000347 |
| The Prevalence of ESBLs Producing Klebsiella pneumoniae Isolates in Some Major Hospitals, Iran. | Aims of this study were to investigate on antibiotic resistance and molecular epidemiology of K.pneumoniae producing ESBLs isolates of respiratory tract infections in some major hospitals in Iran. K.pneumonaie were obtained of patients with RTI. K. pneumoniae producing ESBLs detected by screening, confirming and PCR methods. During the 12-month period, a total of one hundred and thirteen of K.pneumoniae were found from RTI in three cities in different region of Iran which Sixty seven strains (59 ... | 2011 | 21915229 |
| Necrotizing fasciitis following psoas muscle abscess caused by hypermucoviscous Klebsiella pneumoniae. | A 59-year-old Japanese diabetic woman was admitted to a small private hospital with general malaise, fever, and a 1-month history of low back pain. A computed tomography scan of the abdomen revealed left abdominal necrotizing fasciitis with suspected left psoas muscle abscess. She was transferred to Gunma University Hospital, received antibiotic therapy, and underwent debridement of the infected subcutaneous tissue, fascia, and necrotic left psoas muscle. She was transferred to the intensive car ... | 2011 | 22065090 |
| isolation and characterization of a klebsiella oxytoca strain for simultaneous azo-dye anaerobic reduction and bio-hydrogen production. | a facultative anaerobic bacteria strain gs-4-08, isolated from an anaerobic sequence batch reactor for synthetic dye wastewater treatment, was investigated for azo-dye decolorization. this bacterium was identified as a member of klebsiella oxytoca based on gram staining, morphology characterization and 16s rrna gene analysis. it exhibited a good capacity of simultaneous decolorization and hydrogen production in the presence of electron donor. the hydrogen production was less affected even at a h ... | 2011 | 22086069 |
| multidrug-resistant gram-negative bacterial infections after liver transplantation - spectrum and risk factors. | objectives: gram-negative bacilli infections, especially multidrug-resistant gram-negative bacilli infections, are the leading cause of high mortality after liver transplantation. this study sought to investigate the type of infection, infection rate, pathogenic spectrum, antibiotic-resistance profile, risk factors, and epidemiology of multidrug-resistant gram-negative bacterial infection. methods: a retrospective cohort study was conducted and data of 217 liver transplant patients receiving cad ... | 2011 | 22198738 |
| Role of antibiofilm-antimicrobial agents in controlling device-related infections. | Objectives: To assess the effects of N-acetylcysteine (NAC) on organism viability in planktonic and biofilm phases, biofilm thickness, and extracellular polysaccharide content. Methods: We performed time-kill curves and broth macrodilution assays of bacterial and fungal clinical isolates with varying concentrations of NAC. We also created in vitro bacterial biofilms, incubated them with NAC or control, and then stained with propidium iodide and FITC-labeled concanavalin A. We measured biofilm t ... | 2011 | 22094553 |
| dna, protein binding, cytotoxicity, cellular uptake and antibacterial activities of new palladium(ii) complexes of thiosemicarbazone ligands: effects of substitution on biological activity. | the coordination propensities of 4(n,n')-diethylaminosalicylaldehyde-4(n)-substituted thiosemicarbazones (h(2)l(1-4)) were investigated by reacting with an equimolar amount of [pdcl(2)(pph(3))(2)]. the new complexes were characterized by various spectroscopic techniques. the structure determination of the complexes [pd(deasal-tsc)(pph(3))] (1), [pd(deasal-mtsc)(pph(3))] (2) and [pd(deasal-etsc)(pph(3))] (3) by x-ray crystallography showed that ligands are coordinated in a dibasic tridentate ons ... | 2011 | 22051854 |
| biochemical characterization of the tem-107 extended-spectrum β-lactamase in a klebsiella pneumoniae isolate from south korea. | the tem-107 extended-spectrum β-lactamase detected in a klebsiella pneumoniae clinical isolate had a gly238ser substitution compared to the tem-43 β-lactamase. the mic of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. clavulanic acid reduced the mic of ceftazidime 64-fold. | 2011 | 21911565 |
| impact of inappropriate empirical antibiotic therapy on outcome of bacteremic adults visiting the ed. | objectives: to investigate the clinical impact of inappropriate empirical antibiotics on patient outcome and determine the risk factors for mortality in bacteremic adults who visited the emergency department (ed). methods: bacteremic adults visiting the ed from january 2007 to june 2008 were identified retrospectively. demographic characteristics, clinical conditions, bacteremic pathogens, antimicrobial agents, and outcomes were determined from chart records. results: the total of 454 eligible b ... | 2011 | 22205015 |
| Comparison of disc diffusion, Etest and agar dilution for susceptibility testing of colistin against Enterobacteriaceae. | In this study, we compared different methods of colistin susceptibility testing, disc diffusion, agar dilution and Etest using a set of Enterobacteriaceae isolates that included colistin-resistant strains. | 2011 | 21895730 |
| Colonization and infection by colistin-resistant Gram-negative bacteria in a cohort of critically ill patients. | In recent years there has been renewed interest in colistin for the treatment of infections by multidrug-resistant Gram-negative bacteria, causing concern that increasing use may be accompanied by the emergence of resistance. This is a retrospective cohort study of colonization and infection by colistin-resistant (CR) gram-negative bacteria in critically ill patients. Colonization data were based on surveillance culture results. Among 150 patients, 78 (52%) were colonized by CR Gram-negative bac ... | 2011 | 21939468 |
| Isolation and identification of antibacterial compound from the leaves of Cassia auriculata. | Antimicrobial properties of medicinal plants and plant parts such as flowers, roots, fruits, seeds and oils are being used to cure some chronic and acute diseases throughout the world. In the present study, an attempt has been made to isolate and identify the antibacterial compound present in the leaves of the Cassia auriculata. | 2011 | 22013726 |
| Long pentraxin 3 (PTX3) in the light of its structure, mechanism of action and clinical implications. | Pentraxins are a group of evolutionarily conserved ancient proteins. Depending on their structure, pentraxins are divided into short and long pentraxin families. Pentraxin 3 (PTX3) is the prototype of the long pentraxin group. PTX3 synthesis is stimulated by a variety of molecules involved in the inflammatory process. The inflammatory mediator is typically produced at inflammatory sites; however, it can also be released at the sites remote from the original inflammatory insult. Although mainly e ... | 2011 | 21988562 |
| influence of consumption of probiotics on presence of enterobacteria in the oral cavity. | clinical benefits of probiotics have been clearly reported in different gastrointestinal disorders, many of them caused by enterobacteria. the oral cavity is a port of entry and can be an important reservoir of these microorganisms. this work evaluated whether consumption of probiotics was able to influence the presence of enterobacteria in the oral cavity and the specific secretory response against these microorganisms. saliva samples of healthy individuals were collected and plated in macconke ... | 2011 | 22031052 |
| synthesis, spectroscopic properties and antipathogenic activity of new thiourea derivatives. | a number of acylthioureas, 2-((4-methylphenoxy)methyl)-n-(aryl-carbamothioyl)benzamides (aryl = 3,5-dichlorophenyl, 2,3-dichlorophenyl, 3,4-dichloro-phenyl, 2,4,5-trichlorophenyl, 3,4,5-trichlorophenyl, 2-bromophenyl, 2,4-dibromophenyl, 2,5-dibromophenyl, 2-iodophenyl, 3-fluorophenyl, 2,3,4-trifluorophenyl, 2,4,5-trifluoro-phenyl, 2,4,6-trifluorophenyl) have been synthesized, characterized by elemental analysis, ir and nmr spectroscopy and tested for their interaction with bacterial cells in fre ... | 2011 | 21900862 |
| Development of TaqMan real-time polymerase chain reaction for the detection of the newly emerging form of carbapenem resistance gene in clinical isolates of Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii. | The newly emerging form of the so-called New Delhi Metallo-beta-lactamases (NDM-1) has been reported recently from patients worldwide and broadly thought as a potential source for the major global health problem. Thus, it is important to study the epidemiology of the so-called NDM-1 harbouring bacteria to prevent its further spread and to place effective control measures. The present study describes the use of the real-time polymerase chain reaction (PCR) assay for the detection of the bla NDM-1 ... | 2011 | 21860104 |
| high rates of intestinal colonization with extended-spectrum lactamase-producing enterobacteriaceae among healthy individuals. | infections caused by extended-spectrum β-lactamase (esbl)-producing bacteria become an emerging problem in the community setting in many parts of the world. | 2011 | 22068018 |
| [pneumonia-causing bacterial pathogens in intensive care patients]. | this prospective study aimed at determining etiologic agents causing nosocomial pneumonia in a precisely defined group of patients and resistance of bacterial pathogens to antimicrobial drugs. | 2011 | 22052100 |
| multidrug-resistant bacterial colonization of combat-injured personnel at admission to medical centers after evacuation from afghanistan and iraq. | multidrug-resistant organism (mdro) infections, including those secondary to acinetobacter (acb) and extended spectrum β-lactamase (esbl)-producing enterobacteriaceae (escherichia coli and klebsiella species) have complicated the care of combat-injured personnel during operations iraqi freedom and enduring freedom. data suggest that the source of these bacterial infections includes nosocomial transmission in both deployed hospitals and receiving military medical centers (medcens). admission scre ... | 2011 | 21795879 |
| Clinical and bacteriological characteristics of Klebsiella pneumoniae causing liver abscess with less frequently observed multi-locus sequences type, ST163, from Singapore and Missouri, US. | BACKGROUND: Klebsiella pneumoniae is the major cause of liver abscesses in several Asian countries. Differences in the type of circulating Klebsiella strains and/or the genetic make up of the host seem to be plausible explanations for this. METHODS: Two recent K. pneumoniae strains isolated from patients with liver abscess, one from Missouri in the US, and a second one from Singapore, were fully characterized by molecular typing, association of virulent genes, neutrophil phagocytosis, susceptibi ... | 2011 | 22138655 |
| Real-time PCR Analysis of Intestinal Microbiota in Peritoneal Dialysis Patients. | Bifidobacterium and Lactobacillus can beneficially affect the host by producing acetic acid and lactic acid which lower pH and thereby inhibits the growth of pathogens or by competing with pathogens for epithelial adhesion sites and nutrients. The transmural migration of enteric organisms into the peritoneal cavity can cause peritonitis in peritoneal dialysis (PD) patients. We hypothesized that the intestinal microbiota such as Lactobacillus species and Bifidobacterium species differed between P ... | 2011 | 22179250 |
| Efficacy of Pivmecillinam for Treatment of Lower Urinary Tract Infection Caused by Extended-Spectrum ß-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae. | To evaluate the clinical and bacteriological efficacy of pivmecillinam against lower urinary tract infection (UTI) caused by extended-spectrum ß-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae, patients treated for lower UTI with pivmecillinam (n=8) were studied. Patients treated with nitrofurantoin (n=3) and trimethoprim (n=3) or a combination of these agents with pivmecillinam (n=3) were included as a control group. Antimicrobial susceptibility was determined with EUCAST ... | 2011 | 22204597 |
| In vivo antibacterial activity of chinfloxacin, a new fluoroquinolone antibiotic. | OBJECTIVES: To evaluate the in vivo antibacterial efficacy of chinfloxacin, a novel fluoroquinolone, in murine systemic and local infection models. METHODS: The efficacy of chinfloxacin in systemic infection was evaluated in a mouse peritonitis model using isolates of methicillin-susceptible Staphylococcus aureus (MSSA, n?=?3), methicillin-resistant Staphylococcus aureus (MRSA; n?=?1), penicillin-intermediate Streptococcus pneumoniae (PISP; n?=?1), penicillin-resistant S. pneumoniae (PRSP; n?=?2 ... | 2011 | 22210757 |
| Dissemination of the Klebsiella pneumoniae Carbapenemase in the Health Care Settings: Tracking the Trails of an Elusive Offender. | ABSTRACT Transmission of antibiotic resistance genes may be mediated by a variety of molecular mechanisms, from mobility of small genetic elements to clonal spread. Since 1997, the carbapenem-hydrolyzing enzyme Klebsiella pneumoniae carbapenemase (KPC) has spread in the United States and across the world, mainly via a single K. pneumoniae clone, sequence type 258. By tracking the trail of dissemination of the bla(KPC) gene inside their institution, Mathers et al. (mBio 2:e00204-11, 2011) have sh ... | 2011 | 22186612 |
| emergence and risk factors of β-lactamase-mediated resistance to oxyimino-β-lactams in enterobacteriaceae isolates. | we studied 193 enterobacteriaceae isolates presenting diminished susceptibility to oxyimino-cephalosporins recovered in a portuguese hospital (2004-2008). ctx-m-3 producers, firstly detected in portugal, were associated with a klebsiella pneumoniae microepidemic clone. production of ctx-m-type enzymes (ctx-m-1/-3/-9/-14/-15/-32), age ≥65 years, and nosocomial infection were risk factors for higher nonsusceptibility to oxyimino-β-lactams. cmy-2 and dha-1 β-lactamases were only identified in 1% of ... | 2011 | 22209509 |
| functional and phenotypical alterations of polymorphonuclear cells in sézary syndrome patients. | sézary syndrome (ss), the leukemic variant of cutaneous t-cell lymphoma (ctcl), has a poor prognosis and infections represent the most frequent cause of death. polymorphonucleate granulocytes (pmns) constitute an essential part of the innate immune system: their phagocytic and killing activity against pathogens is mediated by the interactions between toll-like receptors (tlrs) and the pathogen-associated molecular patterns (pamps). the aim of this study was to investigate pmn functional activity ... | 2011 | 21951393 |
| Activity of Polymyxin B and the Novel Polymyxin Analogue CB-182,804 Against Contemporary Gram-Negative Pathogens in New York City. | Multidrug-resistant Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa have become common in many regions, often requiring therapy with colistin or polymyxin B. An increase in resistance to these agents would render many infections untreatable. We tested the activity of polymyxin B and the novel polymyxin analogue CB-182,804 against over 5,000 recent Gram-negative clinical isolates from New York City, a region with a high prevalence of multiresistant strains. Over 96% of ... | 2011 | 22196342 |
| defense role of the cocoon in the silk worm bombyx mori l. | silk from the domesticated silk worm bombyx mori procures foreign body response naturally, so it has been utilized as a biomaterial for decades. in india the prime focus of the sericulture industry is to improve silk production with high quality silk. naturally, the silk worm builds its cocoon not only with silk proteins, but also with antimicrobial proteins to avoid infection since the cocoon is non-motile and non-feeding. the aim of the present study is to elucidate the antimicrobial proteins ... | 2011 | 22006381 |
| rapidly fatal community-acquired pneumonia due to klebsiella pneumoniae complicated with acute myocarditis and accelerated idioventricular rhythm. | we describe a previously healthy 52-year-old man with rapidly fatal community-acquired pneumonia caused by klebsiella pneumoniae. the patient developed acute renal dysfunction, accelerated idioventricular rhythm (acute myocarditis), lactic acidosis and septic shock. he died within 15 hours after admission despite intravenous levofloxacin (750 mg daily) and aggressive medical treatment. | 2011 | 22153763 |
| european dissemination of a single oxa-48-producing klebsiella pneumoniae clone. | a klebsiella pneumoniae isolate with decreased susceptibility to carbapenems was isolated in april 2011 in a hospital in amsterdam (the netherlands) and later found to be the source of an important outbreak in a rotterdam hospital. the strain, belonging to sequence type (st) 395, carried the bla(oxa-48) gene located onto a c 62-kb conjugative plasmid, together with the extended-spectrum β-lactamase gene bla(ctx-m-15) . it was closely related or identical to other oxa-48-positive klebsiella pneum ... | 2011 | 21973185 |
| use of meropenem by continuous infusion to treat a patient with a bla(kpc-2)-positive klebsiella pneumoniae blood stream infection. | gram-negative bacterial resistance to antibiotics is of increasing concern. carbapenem resistance among strains of klebsiella pneumoniae is a relatively new phenomenon. resistance attributable to production of carbapenemases is notoriously difficult to combat. | 2011 | 21859337 |
| phytochemical constituents and antibacterial efficacy of the flowers of peltophorum pterocarpum (dc.) baker ex heyne. | to investigate the preliminary phytochemistry and antibacterial activity of the flower extract of peltophorum pterocarpum . | 2011 | 21967698 |
| identification of plasmid-mediated quinolone resistance genes qnra1, qnrb1 and aac(6')-1b-cr in a multiple drug-resistant isolate of klebsiella pneumoniae from chennai. | resistance to fluoroquinolones, a commonly prescribed antimicrobial for gram-negative and gram-positive microorganisms, is of importance in therapy. the purpose of this study was to screen for the presence of plasmid-mediated quinolone resistance (pmqr) determinants in clinical isolates of klebsiella pneumoniae. | 2011 | 21860107 |
| tannin extracts from immature fruits of terminalia chebula fructus retz. promote cutaneous wound healing in rats. | tannins extracted from immature fruits of terminalia chebula fructus retz. are considered as effective components promoting the process of wound healing. the objective of this study is to explore the optimal extraction and purification technology (oept) of tannins, while studying the use of this drug in the treatment of a cutaneous wound of rat as well as its antibacterial effects. | 2011 | 21982053 |
| predictors of in-hospital mortality in elderly patients with bacteraemia admitted to an internal medicine ward. | abstract: | 2011 | 21970460 |
| a multifaceted intervention strategy for eradication of a hospital-wide outbreak caused by carbapenem-resistant klebsiella pneumoniae in southern israel. | to devise a local strategy for eradication of a hospital-wide outbreak caused by carbapenem-resistant klebsiella pneumoniae (crkp). | 2011 | 22080653 |
| prevalence and outcome of hepatobiliary dysfunction in neonatal septicaemia. | : cholestatic jaundice and liver enzyme abnormalities have been reported in neonatal septicaemia; the course, pattern, and outcome of such hepatobiliary dysfunction have not been described. | 2011 | 21873892 |
| the cita/citb two-component system regulating citrate fermentation in escherichia coli and its relation to the dcus/dcur system in vivo. | citrate fermentation by escherichia coli requires the function of the citrate/succinate antiporter citt (citt gene) and of citrate lyase (citcdefxg genes). earlier experiments suggested that the two-component system cita/citb, consisting of the membrane-bound sensor kinase cita and the response regulator citb, stimulates the expression of the genes in the presence of citrate, similar to cita/citb of klebsiella pneumoniae. in this study, the expression of a chromosomal citc-lacz gene fusion was s ... | 2011 | 22101843 |
| cefotaxime for the detection of extended-spectrum β-lactamase or plasmid-mediated ampc β-lactamase and clinical characteristics of cefotaxime-non-susceptible escherichia coli and klebsiella pneumoniae bacteraemia. | we investigated the performance of cefotaxime for the detection of extended-spectrum β-lactamase (esbl) or plasmid-mediated ampc β-lactamase (pampc) and the clinical characteristics of cefotaxime-non-susceptible escherichia coli or klebsiella pneumoniae (ctxns-ek) bacteraemia. all of the consecutive bloodstream isolates between 2005 and 2010 in a japanese university hospital were characterised using polymerase chain reaction (pcr). risk factors and outcomes of ctxns-ek were analysed by multivari ... | 2011 | 22210267 |
| structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers. | despite a long-suspected role in the development of human colorectal cancer (crc), the composition of gut microbiota in crc patients has not been adequately described. in this study, fecal bacterial diversity in crc patients (n=46) and healthy volunteers (n=56) were profiled by 454 pyrosequencing of the v3 region of the 16s ribosomal rna gene. both principal component analysis and unifrac analysis showed structural segregation between the two populations. forty-eight operational taxonomic units ... | 2011 | 21850056 |
| colonisation and infection due to enterobacteriaceae producing plasmid-mediated ampc β-lactamases. | to investigate the epidemiology and clinical features of infections caused by enterobacteria producing plasmid-mediated ampc β-lactamases (pampc), which are emerging as a cause of resistance to extended-spectrum cephalosporins. | 2011 | 22138600 |
| The revival of fosfomycin. | Fosfomycin, originally named phosphonomycin, was discovered in Spain in 1969. There are three forms of fosfomycin: fosfomycin tromethamine (a soluble salt) and fosfomycin calcium for oral use, and fosfomycin disodium for intravenous use. Fosfomycin is a bactericidal antibiotic that interferes with cell wall synthesis in both Gram-positive and Gram-negative bacteria by inhibiting the initial step involving phosphoenolpyruvate synthetase. It has a broad spectrum of activity against a wide range of ... | 2011 | 21945848 |
| impact of restriction of cefepime use on the antimicrobial susceptibility of gram-negative bacilli related to healthcare-associated infections in an orthopedic hospital. | in recent decades, antimicrobial resistance has become a public health problem, particularly in cases of healthcare-associated infections. interaction between antibiotic consumption and resistance development is of particular interest regarding gram-negative bacilli, whose growing resistance has represented a great challenge. | 2011 | 21904460 |
| transient tlr activation restores inflammatory response and ability to control pulmonary bacterial infection in germfree mice. | mammals are colonized by an astronomical number of commensal microorganisms on their environmental exposed surfaces. these symbiotic species build up a complex community that aids their hosts in several physiological activities. we have shown that lack of intestinal microbiota is accompanied by a state of active il-10-mediated inflammatory hyporesponsiveness. the present study investigated whether the germfree state and its hyporesponsive phenotype alter host resistance to an infectious bacteria ... | 2011 | 22210917 |
| Extended spectrum â-lactamase producing multidrug resistant clinical bacterial isolates at National Public Health Laboratory, Nepal. | Extended Spectrum â-lactamase (ESBL) producing multidrug resistant bacteria complicate therapeutic management and limit treatment options. Therefore, detection of ESBL-producing multidrug resistant (MDR) pathogens has a paramount importance. Between April 2009 and January 2010, a prospective study was carried out in National Public Health Laboratory with an objective to determine the status of ESBL producing MDR bacterial isolates from different clinical samples. Identification of the isolates w ... | 2011 | 21991699 |
| Resistance to carbapenems in sequence type 11 Klebsiella pneumoniae is related to DHA-1 and loss of OmpK35 and/or OmpK36. | We investigated the molecular mechanisms of carbapenem resistance in clinical isolates of Klebsiella pneumoniae from Korea and the clinical outcomes of resistant K. pneumoniae infection. Sixteen K. pneumoniae isolates showing resistance to carbapenems collected from a tertiary-care hospital were examined for the mechanisms of carbapenem resistance. PCR and sequencing experiments detected the bla(DHA-1) AmpC ß-1actamase gene in all 16 clinical isolates, while the bla genes of extended-spectrum ß- ... | 2011 | 21940650 |
| Molecular typing and virulence analysis of serotype K1 Klebsiella pneumoniae strains isolated from liver abscess patients and stool samples from noninfectious subjects in Hong Kong, Singapore, and Taiwan. | Serotype K1 Klebsiella pneumoniae with multilocus sequence type 23 (ST23) has been strongly associated with liver abscess in Taiwan. Few data regarding the strain types and virulence of this serotype from other Asian countries are available. Serotype K1 K. pneumoniae strains isolated from liver abscess and stool samples from subjects hospitalized in Hong Kong, Singapore, and Taiwan hospitals were examined. Forty-seven serotype K1 isolates were identified: 26 from liver abscess samples and 21 fro ... | 2011 | 21900521 |
| Characterization and regulation of the 2,3-butanediol pathway in Serratia marcescens. | Serratia marcescens has been proved to be a potential strain for industrial 2,3-butanediol production for its high yield, productivity, and other advantages. In this study, the genes slaA, slaB, slaC, and slaR were successfully cloned which were further confirmed to be encoding acetolactate decarboxylase, acetolactate synthase, 2,3-butanediol dehydrogenase, and a LysR-like regulator, respectively. Unlike in Klebsiella sp. or Klebsiella pneumonie and Vibrio sp. or Vibrio cholerae, the gene slaC i ... | 2011 | 21983710 |
| asymptomatic bacteriuria among an obstetric population in ibadan. | asymptomatic bacteriuria in pregnancy is the major risk factor for symptomatic urinary tract infection during pregnancy. screening and identification of bacteriuria during pregnancy have been recommended. | 2011 | 21984454 |
| sulfoquinovose degraded by pure cultures of bacteria with release of c(3) -organosulfonates: complete degradation in two-member communities. | sulfoquinovose (sq, 6-deoxy-6-sulfoglucose) was synthesized chemically. an hplc-elsd method to separate sq and other chromophore-free sulfonates, e.g. 2,3-dihydroxypropane-1-sulfonate (dhps), was developed. a set of 10 genome-sequenced, sulfonate-utilizing bacteria did not utilize sq, but an isolate, pseudomonas putida sq1, from an enrichment culture did so. the molar growth yield with sq was half of that with glucose, and 1 mol 3-sulfolactate (mol sq)(-1) was formed during growth. the 3-sulfol ... | 2011 | 22150877 |
| chitosan and silver nanoparticles as pudding with raisins with antimicrobial properties. | chitosan nanoparticles (cs-np) containing small silver nanoparticles are reported (ag@cs-np). cs-np was synthesized using tripolyphosphate (tpp) as a polyanionic template. tpp also served to electrostatically attract ag(+) inside cs-np, where it was reduced by the terminal glucosamine units of the biopolymer. this procedure is environmental friendly, inexpensive, and permits the synthesis of very small agnp (0.93-1.7 nm), with only a discrete dependence from the amount of silver nitrate used (5- ... | 2011 | 21903218 |
| augmentation in zone of inhibition of cefoperazone/cefoperazone+ sulbactum compares well with the clinical laboratory standard institute standard extended spectrum beta-lactamase detection method as well as the polymerase chain reaction method. | with increased prevalence of extended spectrum beta-lactamase (esbl) in hospital practice globally, reporting of extended spectrum beta-lactamase along with drug susceptibility test is expected from clinical microbiology laboratory. the aim was to evaluate cefoperazone and cefoperazone+sulbactum disc for phenotypic detection of extended spectrum beta-lactamase among e. coli and klebsiella spp. isolates. | 2011 | 22122390 |
| [Carbapenem resistance in Klebsiella pneumoniae clinical isolates from urinary tract infections]. | Resistance to carbapenems by KPC (Klebsiella pneumoniae carbapenemase) production in Klebsiella pneumoniae clinical isolates was first described ten years ago in the U.S.A. and recently reported in other countries. This enzyme inactivates all beta-lactam antibiotics and is associated with fluoroquinolone and aminoglycoside resistance. | 2011 | 21870752 |
| identification of an antimicrobial peptide from human methionine sulfoxide reductase b3. | human methionine sulfoxide reductase b3a (hmsrb3a) is an endoplasmic reticulum (er) reductase that catalyzes the stereospecific reduction of methionine-r-sulfoxide to methionine in proteins. in this work, we identified an antimicrobial peptide from hmsrb3a protein. the n-terminal er-targeting signal peptide (amino acids 1-31) conferred an antimicrobial effect in escherichia coli cells. sequence and structural analyses showed that the overall positively charged er signal peptide had an argand pro ... | 2011 | 22027001 |
| sensitive and specific modified hodge test for kpc and metallo-beta- lactamase detection in pseudomonas aeruginosa by use of a novel indicator strain, klebsiella pneumoniae atcc 700603. | we evaluated the ability of the modified hodge test to discriminate between kpc- and metallo-beta-lactamase (mbl)-producing pseudomonas aeruginosa isolates and carbapenemase nonproducers. with escherichia coli atcc 25922 as the indicator strain, the mht resulted in low sensitivity, specificity, and repeatability. replacing the indicator strain with klebsiella pneumoniae atcc 700603 led to an improved performance (100%, 97%, 0%, and 100% sensitivity, specificity, indeterminate results and repeata ... | 2011 | 22012019 |
| recurring klebsiella pneumoniae pyogenic liver abscesses in a resident of san diego, california, due to a k1 strain carrying the virulence plasmid. | we report a diabetic patient who had three episodes of cryptogenic liver abscess due to klebsiella pneumoniae. he was a caucasian who lived in california and had no epidemiological connection to east asia. the isolate from his third episode was a hyperviscous k1 strain that carried the klebsiella virulence plasmid. | 2011 | 21998428 |
| antimicrobial susceptibility to parenteral and oral agents in a largely polyclonal collection of ctx-m-14 and ctx-m-15-producing escherichia coli and klebsiella pneumoniae. | activity of oral and parenteral antimicrobials against consecutively isolated extended-spectrum β-lactamase (esbl)-producing escherichia coli (n = 149) and klebsiella pneumoniae (n = 20) was determined, and susceptibility test methods were compared for parenteral β-lactams. polymerase chain reaction (pcr) targeting bla(ctx-m), bla(shv) and bla(tem), and dna sequencing and epidemiological typing with pulsed-field gel electrophoresis were performed. pcr targeting pabb was screened for e. coli o25b ... | 2011 | 22085361 |
| clinical and bacteriological profile of urinary tract infection in children at nepal medical college teaching hospital. | the aim of this study was to study the clinical and bacteriological profile of urinary tract infection (uti) in children. this was a prospective study of 40 culture positive cases of uti in children who attended pediatric outpatient department of nepal medical college teaching hospital. uti was more common in female (65.0%) than in male (35.0%). half were in the age group 1- 5 years. fever was the most common presentation (65.0%) followed by abdominal pain (42.5%), decreased appetite (37.5%) and ... | 2011 | 21991696 |
| bacteriuria among adult non-pregnant women attending mulago hospital assessment centre in uganda. | urinary tract infections (utis) in women are a common problem in primary health care settings. resistance of bacterial uropathogens to commonly used antibiotics is common in many places. | 2011 | 21857848 |
| risk of bacterial colonization of pancreatic stents used in endoscopic retrograde cholangiopancreatography. | background:: pancreatic stents (pss) are commonly inserted at the time of endoscopic retrograde cholangiopancreatography to reduce the risk of pancreatitis. if left in situ for more than 2 weeks, they have been associated with pancreatic duct injury. the mechanism of this injury is not clear, but it may be related to bacterial colonization. aim:: to determine the incidence of ps colonization by microorganisms and the relationship between such colonization and the type, length, diameter, and dura ... | 2011 | 22138843 |
| the disinfecting potential of contact lens soutions used by sultan qaboos university students. | this study aimed to determine the disinfecting potential of some contact lens solutions used by some university students in oman. | 2011 | 21969898 |
| virulence of a klebsiella pneumoniae strain carrying the new delhi metallo-beta-lactamase-1 (ndm-1). | the aim of the study was to compare and evaluate virulence in five strains of klebsiella pneumoniae, including an isolate carrying new delhi metallo-beta-lactamase-1 (ndm-1). in vivo virulence was assessed using a murine sepsis model and using the nematode caenorhabditis elegans killing model, and in vitro virulence by assessing various virulence factors. the ndm-1 carrying k. pneumoniae isolate was the most virulent in the murine sepsis model but there was no clear cut correlation to in vitro v ... | 2011 | 21925284 |
| expression of esbl-like activity in infrequently encountered members of the family enterobacteriaceae. | a collection of 94 unusual members of the enterobacteriaceae were screened for the presence of extended spectrum β-lactamases (esbls) using the microscan esβl plus dried confirmation panel. presumptively positive strains were then confirmed for the presence of an esbl by double disk diffusion, e-test strips (ab biodisk, solna, sweden) and pcr for shv, tem, and ctx-m2 genes. of the 18 strains initially positive on the esβl panel only three strains (leminorella grimontii, klebsiella ozaenae, and k ... | 2011 | 22139464 |
| changes in the clinical features and prognostic factors of endogenous endophthalmitis: fifteen years of clinical experience in korea. | purpose:: to identify changes in the clinical features, management, and prognostic factors of endogenous endophthalmitis in korea from 1996 through 2010. methods:: we conducted a retrospective review of medical records of patients diagnosed with endogenous endophthalmitis from january 1996 to december 2010, which was divided into 3 periods: 1996 to 2000, 2001 to 2005, and 2006 to 2010. variables included age, source of infection, systemic conditions, initial and final visual acuities, causative ... | 2011 | 22105504 |
| antibiotic susceptibility and genotype patterns of escherichia coli, klebsiella pneumoniae and pseudomonas aeruginosa isolated from patients with urinary tract infection. | 2011 | 22184937 | |
| [susceptibility of klebsiella pneumoniae isolated from urinary tract infections to quinolones]. | urinary tract infections (utis) are the most prevalent infections worldwide both in males and females. k. pneumoniae is one of the major pathogens causing utis. fluoroquinolones are effective drugs for treating infections caused by klebsiella spp. the aim of this study was to evaluated the susceptibility to three fluoroquinolones of k. pneumoniae strains isolated from urine. the mics of ciprofloxacin was determined by agar dilution method and the mics of norfloxacin and gatifloxacin by e-test. a ... | 2011 | 22184897 |
| [severe primary liver abscess and septic pulmonary embolism due to klebsiella pneumoniae with hypermucoviscosity phenotype]. | a 70-year-old man with diabetes mellitus seen for fever, right chest pain, and right-lung field consolidation on chest x-ray was found in thoracoabdominal computed tomography (ct) to have variable-sized nodules in both lung fields and multiple low-density hepatic areas. on physical examination, his pulse was 145 beats per minute and blood pressure 92/68mmhg, indicating a preshock state. laboratory tests showed elevated wbc of 15,200/microl, serum-c-reactive protein (crp) of 34.4 mg/dl, and a dec ... | 2011 | 21861440 |
| regulatory role for l: -arginine in the utilization of amino acids by pig small-intestinal bacteria. | we recently reported that bacteria from the pig small intestine rapidly utilize and metabolize amino acids (aa). this study investigated the effect of l: -arginine on the utilization of aa by pure bacterial strains (streptococcus sp., escherichia coli and klebsiella sp.) and mixed bacterial cultures derived from the pig small intestine. bacteria were incubated at 37°c for 3 h in anaerobic aa media containing 0-5 mmol/l of arginine to determine the effect of arginine on the bacterial utilization ... | 2011 | 21928075 |