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colonoscopes may spread hcv and hpv. 200312825588
cost-effectiveness of transfusion of platelet components prepared with pathogen inactivation treatment in the united states.the intercept blood system (ibs) for platelets has been developed to reduce pathogen transmission risks during transfusions.200314604745
hepatitis c virus infection in young, low-income women: the role of sexually transmitted infection as a potential cofactor for hcv infection.we evaluated risk for hepatitis c virus (hcv) infection in women residing in low-income neighborhoods of northern california.200211919070
trends in hepatitis c and hiv infection among inmates entering prisons in california, 1994 versus 1999. 200212409752
care of injection drug users with soft tissue infections in san francisco, california.illicit injection drug use results in serious soft tissue infections that are the number one nonpsychiatric reason for admission to san francisco general hospital (sfgh), san francisco, calif.200212413304
prevalence of hepatitis c infection in a large urban hospital-based sample of individuals with spinal cord injury.to examine the prevalence and clinical characteristics of hepatitis c infection in individuals with chronic spinal cord injury (sci).200212422335
hepatitis c virus infection and needle exchange use among young injection drug users in san francisco.young injection drug users (idus) in san francisco may be at high risk for hepatitis c virus (hcv) infection despite access to several needle exchange venues. the authors conducted a cross-sectional study from 1997 to 1999 in san francisco to estimate the prevalence and incidence of antibody to hcv (anti-hcv) among street-recruited idus under age 30, and to examine risk behaviors and sources of sterile needles. among 308 participants, the prevalence of anti-hcv was 45%. using statistical modelin ...200111431749
chronic hepatitis c in ethnic minority patients evaluated in los angeles county.the aim of this study was to compare demographic, clinical, and histological features of hepatitis c in four ethnic groups seen at the los angeles county/university of southern california hepatitis clinic.200111513187
bloodborne pathogen exposures in a developmental center: 1993-2000.in a developmental center, 257 potential bloodborne pathogen exposures (119 bites, 91 scratches, 30 sharps injuries, 17 mucosal breaks) occurred during 8 years (13,187 employee-years and 6,980 resident-years). of the residents, 9% were hepatitis b virus (hbv) surface antigen carriers. serological follow-up of exposed, susceptible employees and residents identified no transmission of hbv, hepatitis c virus (hcv), or human immunodeficiency (hiv) virus. this outcome has been due primarily to hepati ...200111519919
no direct role for epstein-barr virus in american hepatocellular carcinoma.epstein-barr virus (ebv) was recently linked to hepatocellular carcinogenesis in japanese patients. it is not clear whether ebv infection is also associated with hepatocellular carcinoma (hcc) occurring in american patients. we studied 41 cases of hcc from the los angeles area for evidence of ebv infection by in situ hybridization, immunohistochemistry, and polymerase chain reaction methods. of 41 cases, 16 were seropositive for hepatitis b virus surface antigen (39%), 9 of 29 tested were seropo ...200111583956
action needed to stem hiv, hepatitis c in california prisons. 200111668826
screening for chronic hepatitis b and c virus infections in an urban sexually transmitted disease clinic: rationale for integrating services.clients attending sexually transmitted disease (std) clinics are at risk for multiple infections (e.g., stds, hiv, and infectious viral hepatitis). risk assessment and serosurveys can document the need for hepatitis screening and vaccination services.200111289199
risk of infection from needle reuse at a phlebotomy center.this study determined infection risk for hiv, hepatitis b virus (hbv), and hepatitis c virus (hcv) from needle reuse at a phlebotomy center that possibly exposed 3810 patients to infection.200111291380
prevalence and duration of hepatitis c among injection drug users in san francisco, calif. 200111189823
epidemiology of hepatitis c virus infection in american veterans.this study reports the findings of hepatitis c virus (hcv) infection in a large department of veterans affairs health care system in suburban northern california.200010710068
prevalence of hiv infection, sexually transmitted diseases, and hepatitis and related risk behavior in young women living in low-income neighborhoods of northern california.to estimate the prevalence of human immunodeficiency virus (hiv) infection, sexually transmitted diseases, and hepatitis and the associated sexual and drug-using behavior among women residing in low-income neighborhoods in 5 northern california counties.200010854379
hepatocellular carcinoma: an emerging problem with hepatitis c.hepatocellular carcinoma (hcc) is emerging as a major problem in the united states, primarily due to the development of liver cancer in patients with cirrhosis secondary to the hepatitis c virus. the diagnosis of hcc in patients with underlying cirrhosis can be achieved at an early stage if appropriate diagnostic measures are pursued by primary care physicians and gastroenterologists. african americans are particularly vulnerable in developing hcc since their response to current therapy for chro ...200010992680
characterization of anti-hepatitis c virus-positive sera not genotyped by restriction fragment length polymorphism or serology.the hepatitis c virus genome is extremely heterogeneous and has been classified into six major genotypes. genotyping of hepatitis c has been achieved through both direct molecular approach and indirect detection of host genotype-specific antibodies by serological methods. the purpose of this study was to characterize anti-hepatitis c positive sera samples that were not genotyped either by restriction fragment length polymorphism or by serology.199910207783
prevalence and correlates of hepatitis c virus infection among inmates entering the california correctional system.to estimate the prevalence and predictors of hepatitis c virus (hcv) infection among inmates, a cross-sectional survey was conducted in 1994 among inmates entering six reception centers of the california department of corrections. discarded serum samples were tested for antibodies to human immunodeficiency virus (hiv), hcv, hepatitis b core, and hepatitis b surface antigen (hbsag). of 4,513 inmates in this study, 87.0% were men and 13.0% were women. among male inmates, 39.4% were anti-hcv-positi ...199910214102
chronic infection with hepatitis g virus in relation to hepatocellular carcinoma among non-asians in los angeles county, california.the recently identified hepatitis g virus (hgv) is a hepatotropic rna virus belonging to the flaviviridae family. the virus causes chronic viremia, and exposure to blood products is a recognized route of transmission in humans. to the authors' knowledge there is scant information regarding the hepatocarcinogenic potential of hgv. the current study examined the association between hgv infection and the risk of hepatocellular carcinoma.199910491518
the role of needle exchange programs in hiv prevention.injecting drug users (idus) are at high risk for infection by human immunodeficiency virus (hiv) and other blood-borne pathogens. in the united states, idus account for nearly one-third of the cases of acquired immunodeficiency syndrome (aids), either directly or indirectly (heterosexual and perinatal cases of aids where the source of infection was an idu). idu also account for a substantial proportion of cases of hepatitis b (hbv) and hepatitis c (hcv) virus infections. the primary mode of tran ...19989722812
a prospective study of the risk of transfusion-acquired viral infections.the risk of transfusion-transmitted viral infections may be estimated by several methods, but only prospective studies of transfusion recipients can directly measure the incidence, with associated 95% upper confidence bound, of these infections. from 1989 through 1995, 764 recipients of allogeneic or autologous red blood cell transfusions were enrolled; 486 (64%) provided both pretransfusion and 6-month follow-up specimens. both specimens were tested for anti-hbc, anti-hcv, anti-htlv-i and anti- ...19989800288
fifteen-year experience with adult and pediatric liver transplantation at the university of california, los angeles.in the past 6 years, advances in surgical technique and immunosuppression regimens have improved overall survival of transplant patients. hepatitis c and alcoholic cirrhosis are the most common indications for transplantation at this center in the adult population while biliary atresia remains the most common indication in children. organ shortages remain the most formidable obstacle to widespread application of organ transplantation. as recipient indications and criteria for transplantation exp ...199810503104
california approves compassionate release, viatical bill.governor pete wilson of california vetoed six of ten hiv-related bills approved by the democrat-led legislature. a plan to encourage people living with aids to return to work and a bill to demonstrate the cost-effectiveness of public health care provision for hiv-positive patients whose disease has not progressed to aids were among those rejected by governor wilson. the governor did approve assembly bill 29, granting early prison release to terminally ill inmates who apply through the courts. as ...199711364781
hepatitis c virus infection in patients with b-cell non-hodgkin lymphoma.several studies from europe have reported a high prevalence (9% to 32%) of chronic hepatitis c virus (hcv) infection in patients with b-cell non-hodgkin lymphoma. it has been suggested that hcv plays a role in the pathogenesis of b-cell non-hodgkin lymphoma.19979312998
a four-year review of patients with hepatitis c antibody in department of veterans affairs facilities.hepatitis c virus [hcv] has recently been recognized as an emerging pathogen of surprising proportions. the clinical liver illness associated with hcv infection can be minimal or none, but in a notable number of persons it can ultimately cause debilitating chronic liver disease, fibrosis, cirrhosis, and hepatic failure, and it is likely related to an increased incidence of hepatocellular carcinoma. from 1991 to 1994, an annual electronic census was sent to 168 veterans health administration faci ...19979358714
evaluation of hepatitis b and c viral markers: clinical significance in asian and caucasian patients with hepatocellular carcinoma in the united states of america.in order to evaluate the roles of hepatitis b virus (hbv) and hepatitis c virus (hcv) and their clinical significance in asian-american and caucasian patients with hepatocellular carcinoma (hcc) in the usa, 110 hcc patients, seen in a community-based teaching hospital in the los angeles area over a 10 year period, were enrolled. seventy-nine (72%) patients were asian-american and 31 (28%) were caucasians. of the 110 hcc patients, 69 (63%) were positive for serum hepatitis b surface antigen (hbsa ...19968912133
hiv rate in ca prisons higher than in community.health officials in california have found that the hiv rate among the state's prison population has remained relatively stable since 1988. the most recent figures, which were gathered during a massive communicable disease screening of 118,000 inmates and employees of the state correctional system, indicate that 2.5 percent of male inmates and 3.2 percent of female inmates are hiv-positive. the health care workers were particularly concerned because both hepatitis b virus (hbv) and hepatitis c vi ...199611363237
application of six hepatitis c virus genotyping systems to sera from chronic hepatitis c patients in the united states.serum samples from 139 us patients with chronic hepatitis c virus (hcv) infection were studied using six different genotyping systems, including both molecular and serologic methods, to determine the applicability of these approaches and the prevalence of various hcv subtypes. the concordance of genotyping results based on the various systems (except for core polymerase chain reaction genotyping) was good (93.5%). subtypes 1a and 1b were prevalent (37.4%). subtypes 2a (2.2%), 2b (8.6%), and 3a ( ...19957844363
outbreak of hepatitis c associated with intravenous immunoglobulin administration--united states, october 1993-june 1994.on february 21, 1994, the food and drug administration (fda) was notified of 14 possible cases from three different countries of acute hepatitis c among persons who had received gammagard, an intravenous immunoglobulin (igiv) product manufactured by baxter healthcare corporation (glendale, california). the company removed gammagard from the worldwide market on february 23, 1994. the american red cross removed polygam (igiv manufactured by baxter healthcare from american red cross plasma) from th ...19948022396
risk factors for hepatitis c virus infection among health care personnel in a community hospital.to determine the prevalence of and risk factors for antibody to the hepatitis c virus in hospital employees.19937694529
seroepidemiology of viral infections among intravenous drug users in northern california.intravenous drug users are frequently exposed to parenterally transmitted viral infections, and these infections can spread to the general population through sexual activity. we investigated the prevalence of serologic markers for human immunodeficiency virus type 1 (hiv-1), human t-cell lymphotropic virus type i/ii (htlv-i/ii), hepatitis b virus (hbv), and hepatitis c virus (hcv) in intravenous drug users and their sexual contacts. of 585 drug users from northern california tested for these ser ...19921310362
molecular cloning and sequence analysis of an isolate of hepatitis c virus from southern california, u.s.a.we obtained a cdna clone representing a partial rna sequence of a human hepatitis c virus (hcv) isolate from southern california. rna was extracted from the liver tissue of a patient with post-transfusion hepatitis, and used for cdna synthesis and polymerase chain reaction (pcr) amplification using oligonucleotide primers specific for the prototype hcv rna. the cdna clone obtained contains 585 base pairs of hcv sequences and represents the region encoding the putative nonstructural protein ns3 o ...19921364214
prevalence of hepatitis c virus antibodies among patients infected with human immunodeficiency virus.a study was undertaken to determine the prevalence and risk factors for serological evidence of hepatitis c virus (hcv) infection in patients infected with the human immunodeficiency virus (hiv). tests for anti-hcv antibody were carried out by enzyme-linked immunoassay (eia) on 101 hiv-infected patients from two university-based outpatient clinics. anti-hcv antibody reactive samples were tested by using a recombinant immunoblot assay (riba) for hcv antibodies. fourteen of 101 (13.9%) hiv-infecte ...19911715384
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