Publications

[study of the chemo-antibiotic resistance of n. meningitidis].		1972	4626164
a world look at the venereal diseases: recrudescence of the venereal diseases.	factors affecting the increased incidence of the venereal diseases syphilis and gonorrhea throughout the world since world war 2 are considered. both diseases declined after the war to a minimum in about 1957, but they have since increased, particularly gonorrhea to even higher incidence in many countries. late and congenital syphilis, however, have declined almost universally. factors invoked to explain the recrudescence include decreased virulence of both organisms, perhaps aided by better ...	1972	4626515
asymptomatic gonorrhea.		1972	4626516
the fate of gonococci in polymorphonuclear leucocytes: an electron microscopic study of the natural disease.		1972	4626705
treatment of gonorrhoea.		1972	4626744
[specific tonsillar angina in a homosexual young man with gonorrheal urethritis].		1972	4626769
influence of sodium chloride on growth of neisseria meningitidis.	nasopharyngeal isolates of neisseria meningitidis were tested for growth on nutrient agar with and without the addition of 0.8% sodium chloride. of the 822 strains tested, 1.3% grew on the salt-free medium, and 74.1% grew on the medium supplemented with sodium chloride.	1972	4626905
efficiency of a transport medium for the recovery of aerobic and anaerobic bacteria from applicator swabs.	the survival of four aerobic and four anaerobic pathogens was evaluated quantitatively on cotton swabs and calcium alginate swabs stored in dry tubes as compared with swabs stored in amies transport medium without charcoal. survival of the pathogens was markedly improved when stored in amies transport medium, although there was considerable loss of viability after a few hours of storage.	1972	4626907
neisseria gonorrhoeae: experimental infection of laboratory animals.	experimlental neisseria gonorrhoeae infections were established in five species of small laboratory animals (rabbits, guinea pigs, hamsters, mice, and rats) after subcutaneolusly implanted chambers were inioculated with gonococci. the chamber fluid was easily available for study or culture. a systemic immune response was indicated by hemnagglutination assay.	1972	4626945
gonorrhoea in the chimpanzee. infection with laboratory-passed gonococci and by natural transmission.		1972	4627047
sulphamethoxazole-trimethoprim in the treatment of gonorrhoea.		1972	4627048
immunoelectroosmophoresis in the diagnosis of meningococcal infections.	specimens of cerebrospinal fluid and serum from 22 cases of meningococcal infection were examined by immunoelectroosmophoresis and the results compared with those obtained by microscopy and culture. the results were the same except that three of 10 cases of group b infection were not diagnosed by immunoelectroosmophoresis and two of 10 cases of group c infection were not diagnosed by culture. the sensitivity of the method depends on the potency of the antiserum used and antisera from commercial ...	1972	4627102
[neisseria gonorrheae susceptibility to drugs with special reference to beta-lactam groups].		1972	4627112
cultivation and properties of neisseria sp. grown in chemically defined media.		1972	4627142
ruptured mycotic pericallosal aneurysm with meningitis due to neisseria meningitidis infection. case report.		1972	4627162
carbonic anhydrase from neisseria sicca, strain 6021. i. bacterial growth and purification of the enzyme.		1972	4627452
carbonic anhydrase from neisseria sicca, strain 6021. ii. properties of the purified enzyme.		1972	4627453
intrafamilial infection with neisseria meningitidis, group c. an intense intramural meningeal infestation in a family.		1972	4627455
neisseria meningitidis cellulitis.		1972	4627487
affinity chromatography of anti-meningococcal antiserum.		1972	4627512
meningococcemia in a newborn infant whose mother had meningococcal vaginitis.		1972	4627520
"anaerobic" growth of gonococci, and candle jars.		1972	4627608
frozen human plasma and bacterial contamination.		1972	4627788
[asymptomatic gonorrhea in women with unplanned pregnancy].		1972	4627848
susceptibility of neisseria gonorrhoeae to seven antibiotics in vitro.	one hundred consecutive isolates of n. gonorrhoeae were tested for susceptibility to penicillin, ampicillin, tetracycline, erythromycin, kanamycin, cephaloridine and cephalexin by an agar dilution method. relative resistance to penicillin was frequent. for 39% of isolates the minimum inhibitory concentration (mic) of penicillin was 0.05 u./ml. or less; in 55% the mic was 0.5 to 2.0 u./ml. ampicillin was slightly more active than penicillin g: all isolates were inhibited by 0.5mug./ml. or less. r ...	1972	4628259
studies on gonococcus infection. ii. freeze-fracture, freeze-etch studies on gonocci.	gonococci have been studied by electron microscopy after freeze-cleavage, freeze-etching and the findings correlated with those obtainable through thin sectioning and negative staining. the outer membrane of the cell wall is composed of round to hexagonal subunits 80 a in diameter. this membrane is also punctuated by 80-a holes visible on the exterior of the organism and extending into the substance or through the outer membrane. pili coursing over the surface of the organisms appear to maintain ...	1972	4628335
[treatment of gonorrhea].		1972	4628719
meningococcal meningitis in new zealand with special reference to carrier rates in military trainees.		1972	4628971
latex agglutination test for measurement of antibodies to meningococcal polysaccharides.	a latex agglutination test employing serogroup-specific meningococcal polysaccharides as the antigen has been developed. the test has been used to measure serological responses in patients with meningococcal disease, in meningococcal carriers, and in volunteers who received meningococcal vaccines. it has been shown to be a sensitive and highly specific test for the detection of group-specific meningococcal antibody. the advantages of standardized particles and antigens which are simple to prepar ...	1972	4629077
cross-protective antigens of neisseria meningitidis obtained from slaterus group y.	an extraction of the cells of neisseria meningitidis serogroup y with an aqueous solution of calcium choride (0.9 m) has been shown to solubilize a number of antigens. by immunodiffusion, this mixture of antigens has been shown to react with its group-specific antiserum and also to cross-react with a number of other group-specific antisera. the cross-reacting antigen appears to be an antigen common to a number of other serogroups of meningococci, and there is some evidence that it is protein in ...	1972	4629126
serum and nasal secretion immune response in meningococcal disease.	nasal antibodies to meningococcal organisms were demonstrable by the indirect fluorescent-antibody test in three patients. serogroup cross-reactions were usual.	1972	4629128
production and degradation of serogroup b neisseria meningitidis polysaccharide.	polysaccharide produced from cultures of serogroups a, b, and c neisseria meningitidis was assayed by the serogroup-specific hemagglutination inhibition (hai) test. the polysaccharide produced by all serogroups was found to increase during the exponential phase of growth. for serogroups a and c, the hai activity was stable during the stationary phase; for serogroup b, however, the hai decayed rapidly. the degradation of the serogroup b polysaccharide was not caused by enzymatic degradation, but ...	1972	4629201
classification of neisseria meningitidis group b into distinct serotypes. iv. preliminary chemical studies on the nature of the serotype antigen.	group b neisseria meningitidis has been subdivided into 11 distinct serotypes by a sensitive bactericidal inhibition technique. the antigens responsible for induction of bactericidal type-specific antibodies were found to be extractable from the group b cells with heating at 100 c either by 0.017 n hcl in saline or by normal saline. these extracted serotype antigens were detected by a capillary precipitin test. the development of methods for extraction and assay of the serotype antigens permitte ...	1972	4629202
physicochemical properties of neisseria meningitidis group x polysaccharide antigen.	neisseria meningitidis group x occurs in human carrier populations and is rarely implicated in serious disease. this organism possesses a capsular group antigen which is an acidic polysaccharide. it is composed of the amino sugars, glucosamine, glucosamine-6-phosphate, galactosamine, and the simple hexose, glucose. the group x capsular antigen has an s(20,w) (0) of 3.6, and the acidic nature of the polysaccharide is reflected in an isoelectric point of 3.65. the meningococcal a, b, c, and y poly ...	1972	4629206
isolation and characterization of a native cell wall complex from neisseria meningitidis.	a cell wall complex has been isolated by gentle methods from both the medium supernatant fluid and whole organisms of neissieria meningitidis cultures. the two types of preparations have been shown to be essentially identical on the basis of chemical composition, electron microscopy, and polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate (sds-page). four major components were identified in the complex: group-specific polysaccharide (4 to 10%), protein (45 to 65%), lipop ...	1972	4629210
response of mice to injection of ribosomal fraction from group b neisseria meningitidis.	ribosomes of strain nor-7 of group b neisseria meningitidis were isolated by a procedure that included treatment of the cells with sodium dodecyl sulfate, disruption in a french pressure cell, and differential centrifugation. these preparations consisted of 66% ribonucleic acid and 24% protein and sedimented as a single component with a constant of approximately 66s. when used in immunodiffusion tests with homologous rabbit antiserum, untreated ribosomes formed two precipitin lines, when treated ...	1972	4629260
[gonococcal eye-infection in an 8-year-old boy].		1972	4629759
bacteriological findings in acute maxillary sinusitis.		1972	4405604
[clinical significance of pseudogonococci. diagnosis and treatment].		1972	4483558
does prior antibiotic treatment hamper the diagnosis of acute bacterial meningitis? an analysis of a series of 135 childhood cases.		1972	4401990
6 -amidinopenicillanic acids--a new group of antibiotics.		1972	4402006
changing patterns of susceptibility of common bacterial pathogens to antimicrobial agents.		1972	4402139
acute bacterial meningitis in childhood: an outline of management.		1972	4403326
diagnosis of bacterial meningitis by counterimmunoelectrophoresis.		1972	4403430
the bacterial etiology and antibiotic management of septic arthritis in infants and children.		1972	4403468
[etiopathogenetic significance of bacteria for bronchial asthma].		1972	4403583
phagocytosis as a surface phenomenon. contact angles and phagocytosis of non-opsonized bacteria.		1972	4403781
the effect of oral microbial endotoxins on phagocytosis of 14 c-labelled starch granules by rabbit polymorphonuclear leukocytes.		1972	4502043
isolation and description of a haemolytic species of neisseria (n. ovis) from cattle with infectious keratoconjunctivitis.		1972	4502347
neisseria elongata. presentation of new isolates.		1972	4509398
classification of neisseria meningitidis group b into distinct serotypes. ii. extraction of type-specific antigens for serotyping by precipitin techniques.	over 10 distinct serotypes of group b neisseria meningitidis have been found to date by using a sensitive microbactericidal assay developed by the authors. the serotype antigens have now been extracted by hot acid or saline extraction procedures. it was found that these extracted serotype antigens may be used in a simple capillary precipitin method. this method uses unadsorbed, undiluted rabbit antisera. in the capillary precipitin method a 3+ to 4+ reaction was considered significant. the micro ...	1972	4631911
therapy of acute meningococcal infections: early volume expansion and prophylactic low dose heparin.		1972	4631175
studies in venereal disease. i. isolation of l-phase organisms of n. gonorrhoeae from patients with gonorrhoea.		1972	4631229
mutation of gonococci and meningococci in vitro to rifampin (rifampicin) resistance.		1972	4631230
pivampicillin hydrochloride in uncomplicated gonorrhoea.		1972	4631231
treatment of gonorrhoea with cotrimoxazole, procaine penicillin alone, and procaine penicillin plus probenecid.		1972	4631232
characterization of spheroplast membranes of neisseria meningitidis group b.	spheroplast membranes (spheroplast envelopes) of strain 2091 of group b neisseria meningitidis were prepared by a procedure that included lysozyme treatment of the cells and osmotic lysis of the resulting spheroplasts. electron microscopy revealed that the membranes consisted of two unit layers, generally parallel to each other. the membrane preparation migrated as a single component in a 40 to 70% sucrose gradient and consisted of 62% protein, 28% lipid, 9% ribonucleic acid, small amounts of ca ...	1972	4630722
incidence of haemagglutinating antibodies to meningococci in north-west england.	using an indirect haemagglutination technique the incidence of meningococcal antibodies in adults was found to be: group a 21%, group b 3%, and group c 20%. the reasons for some differences between these results and those obtained in america are discussed. a low incidence of antibody was detected in preschool children but the incidence in school children was found to approach that of adults. comparison of the antibody incidence in the adult population of an area where clinical infections were oc ...	1972	4630731
[diagnosis of gonorrhea using immunofluorescence].		1972	4630771
[case of gonorrheal gonarthritis in a 7-year-old girl].		1972	4630609
meningococcal arthritis.		1972	4630118
preliminary study of colony type stability of neisseria gonorrhoeae in liquid culture.		1972	4630224
treatment of gonococcal urethritis with a single dose of doxycycline monohydrate.		1972	4630225
venereal disease among nigerian women attending intra-uterine contraceptive device clinics.		1972	4630277
[incidence of l-transformation of n. meningitidis isolated from cerebrospinal fluid in epidemic cerebrospinal meningitis].		1972	4630302
[immunosuppressive action of rifampicin].		1972	4554692
bacterial content of the gastric juice.		1972	4555541
oropharyngeal cultures of patients in protected environment units: evaluation of semiquantitative technique during antibiotic prophylaxis.	a semiquantitative culture technique was used to monitor the microbial flora of the oropharynx of 30 patients receiving antibiotic prophylaxis in protected environment units. after institution of antibiotic prophylaxis, the median concentration of organisms in the oropharynx fell by 2 logs but gradually increased by 1 log and then remained stable. neisseria spp., micrococcus sp., and streptococci were generally eradicated by the antibiotics but were replaced by lactobacilli and yeast. four of ni ...	1972	4555635
an unclassified gram-negative rod isolated from the pharynx on thayer-martin medium (selective agar).	an oxidase-positive, small gram-negative rod was isolated on thayer-martin medium (tm) inoculated with pharyngeal swabs obtained during surveys to detect neisseria carriers. in one survey, this organism was isolated from 48% of the subjects, and 50 or more colonies were present on the majority of the primary isolation plates. other characteristics of the organism, which has been given the provisional designation "tm-1," include: delayed production (2 to 10 days) of acid from glucose, formation o ...	1972	4565636
intestinal flora in patients with chronic bronchitis and malabsorption syndrome.		1972	4566591
[antagonism limit of penicillin g and chloramphenicol on neisseria meningitidis].		1972	4633499
[cutaneous localizations of gonococcal infections].		1972	4632752
[benign gonococcic septicemia with cutaneous localizations].		1972	4632753
[current aspects of epidemic cerebrospinal meningitis in rumania].		1972	4632611
latex agglutination in the diagnosis of meningococcal meningitis.	group-specific polysaccharides of neisseria meningitidis groups a and c have been demonstrated by means of a rapid, sensitive slide agglutination test with latex particles coated with antibodies. in this manner, the diagnosis can be made from the cerebrospinal fluid of patients with meningococcal meningitis caused by serogroups a or c even when the culture is negative. the method appears to be more sensitive than countercurrent immunoelectrophoresis and less elaborate.	1972	4632330
relationship of serogroups of neisseria meningitidis. ii. r variants of neisseria meningitidis.	meningococci isolated in primary cultures from nasopharyngeal carriers occasionally consisted of mixtures of smooth (s) and rough (r) strains. the r strains were separated from the s strains and their morphological and serological characteristics were studied. some of these r strains reverted spontaneously to s strains which subsequently produced group-specific polysaccharide. several r strains, grown in the presence of deoxyribonucleic acid from either an r strain of known parentage or an s str ...	1972	4632468
classification of neisseria meningitidis group b into distinct serotypes. i. serological typing by a microbactericidal method.	neisseria meningitidis group b was subdivided into a number of different serotypes. a sensitive microbactericidal assay procedure was developed, and, with this method, over 10 different serotypes were provisionally established. the method by which distinct serotype designations were assigned is described. almost half of the strains examined thus far contained a common serotype antigen which was distinct from the grouping antigen. differentiation of group b meningococci into distinct types will a ...	1972	4632471
[meningococcus serogroups].		1972	4632513
a study of meningococci isolated from patients and carriers in israel during 1966-71.		1972	4632138
screening for gonococcal arthritis.		1972	4633463
biological activity of a surface component of neisseria meningitidis.		1972	4633973
[preventive meningococcal immunology].		1972	4633974
the immunological responses observed in field studies in africa with group a meningococcal vaccines.		1972	4633975
[antimeningococcal vaccination in member states of the organization for coordination and cooperation in the control of major epidemics].		1972	4633976
trial of a serogroup a meningococcus polysaccharide vaccine in nigeria.		1972	4633977
[studies on the normal occurrence of neisseria flavescens (branham, 1930)].		1972	4641940
minocycline in the chemoprophylaxis of meningococcal disease.	an outbreak of meningococcal disease occurred among basic combat trainees at fort lewis, wash., in the first 3 months of 1971. after five recruits developed meningitis within a 2-week period, 8,721 recruits were given 100 mg of minocycline every 12 hr for 5 days. no new cases of meningococcal disease occurred for almost 5 weeks. then six additional cases occurred among recruits who had entered training after the initial course of minocycline and who had not received the drug. minocycline was giv ...	1972	4670480
[biochemical bases of caries etiology].		1972	5014138
the current state of gonorrhoea therapy. particularly with regard to the decrease of penicillin sensitivity of neisseria gonorrhoeae.		1972	5014427
neonatal conjunctivitis.		1972	5031232
biological characterization of diumycin, a phosphorus-containing glycolipid antibiotic.		1972	5034812
conjunctival flora of clinically normal dogs.		1972	5036187
dietary sterols: role in larval feeding behaviour of the southwestern cornborer, diatraea grandiosella.		1972	5036587
["neisseria mucosa" responsible for purulent meningitis of children].		1972	5040222
[infections of the eye. microbiology and therapeutic results using gentamycin].		1972	5049623
the role of gonococcus in acute pelvic inflammatory disease in nairobi.	the research objective was to determine how often gonorrhea could be found in pelvic inflammatory disease (pid) using a simple bacteriological method. 58 consecutive patients who were admitted to the acute gynecological ward of the kenyatta national hospital in nairobi were investigated. the diagnosis of pid was made clinically. the common presenting features were: pyrexis; pain in the lower abdomen; vaginal discharge; and bilateral adnexal tenderness. specimens were taken from pus or disch ...	1972	5075423
resistance of rats to experimental infection with neisseria gonorrhoeae despite attempts to alter cellular and humoral defences.		1972	5083442
influence of cultural conditions on the lipopolysaccharide composition of neisseria sicca.		1971	5089334
[heterotrophic microflora of amu-dar'ya surface waters and their significance in the mineralization of organic matter].		1971	5096617
septic gonococcal dermatitis.	the overall incidence in gonorrhoea of septic gonococcal dermatitis was found to be 1.9% (3% for the females and 0.7% for the males). in 23 patients the common presenting symptoms were arthritis or arthralgia and bouts of fever, but the characteristic skin lesions served as an early clue to the diagnosis, and neisseria gonorrhoeae was isolated from the genitourinary tract or from the blood. with the use of immunofluorescent techniques gonococci were also found in smears prepared from the skin le ...	1971	5101355