Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| genetic characterization of african swine fever viruses from a 2008 outbreak in tanzania. | outbreaks of african swine fever (asf) have been reported in the past from several countries in sub-saharan africa. the aim of this study was to genotype asf viruses (asfvs) from the 2008 outbreak in morogoro and dar es salaam regions of tanzania. tissue samples from domestic pigs that died as a result of severe haemorrhagic disease were collected and analysed with pcr and genome sequencing methods using asfv-specific primer sets. nucleotide sequence data were obtained for the b646l (p72), e183l ... | 2010 | 21214868 |
| cloning, characterization and diagnostic performance of the salivary lipocalin protein tsgp1 from ornithodoros moubata. | the argasid tick ornithodoros moubata is distributed throughout south and east africa and madagascar, where it colonizes wild and domestic habitats and feeds on warthogs, domestic swine, and humans. this argasid transmits the spirochete borrelia duttonii, causing east african tick-borne relapsing fever in humans, and the african swine fever virus, which causes a highly lethal haemorrhagic disease in pigs. tick surveillance and the elimination of o. moubata from synanthropic environments (human d ... | 2010 | 21216104 |
| distribution of orf2 and orf3 genotypes of porcine circovirus type 2 (pcv-2) in wild boars and domestic pigs in germany. | porcine circovirus 2 (pcv-2), the essential infectious agent in pcvd (porcine circovirus diseases) circulates at high rates among domestic pig and wild boar populations. wild boars may be viremic and shed the virus with excretions and secretions, and thus serve as a reservoir for domestic pig pcv-2 infection. we hypothesize that pcv-2 strains circulating in wild boars and in domestic pigs are significantly different and thus, partially independent. to prove this hypothesis, the present study inv ... | 2010 | 20869816 |
| confirmation of needle cricothyroidotomy using an esophageal detector device in a porcine model. | the difficult intubation is one of the most trying situations encountered in airway management. transtracheal jet ventilation via needle cricothyroidotomy can provide temporary oxygenation in this critical situation in a minimally invasive fashion. the esophageal detector device (edd) has been previously shown to be effective in determining the tracheal placement of endotracheal tubes. in this experiment, three commonly available edds are utilized to accurately identify 15 of 15 intratracheal pl ... | 2010 | 20882932 |
| a novel device for rapid cleaning of poorly prepared colons. | adequate colon preparation is essential for the quality and accuracy of colonoscopy and has a significant influence on related costs. the aim of this study was to assess the efficacy and safety of a novel attachable colon-cleaning device used during colonoscopies in porcine colon. | 2010 | 20886401 |
| the effect of nesting material on the nest-building and maternal behavior of domestic sows and piglet production. | nest building is an important part of maternal behavior in domestic pigs. the aim of the study was to assess the effect of nesting material sawdust vs. straw on sow behavior 24 h before and after birth of the first piglet (bfp) and piglet production. sows, housed in farrowing crates, were randomly divided into 2 treatments: sawdust (n = 12) and straw (n = 13). sawdust and straw were provided during the pre- and parturient period; after parturition, straw was given to both experimental groups. th ... | 2010 | 20889685 |
| meiotic studies in infertile domestic pig-babirusa hybrids. | mating of a babirusa (babyrousa babyrussa) boar and a domestic sow (sus scrofa) resulted in the birth of 5 live domestic pig-babirusa hybrid piglets. chromosome analysis of one of the surviving males confirmed that they were domestic pig-babirusa hybrids by revealing the presence of a complete haploid set of 19 porcine chromosomes as well as a complete haploid set of 19 babirusa chromosomes in the karyotype. none of the surviving piglets, two males and one female, had shown signs of sexual matur ... | 2010 | 20924163 |
| identification of a novel astrovirus in a domestic pig in hungary. | the family astroviridae consists of two genera, avastrovirus and mamastrovirus, whose members are associated with gastroenteritis in avian and mammalian hosts, respectively. we serendipitously identified a novel porcine astrovirus in a fecal specimen from a domestic pig (sus scrofa domestica) in hungary. sequencing of a fragment indicated that it was an orf1b/orf2/3'utr sequence, and it has been submitted to the database as porcine astrovirus type 2 (pastv-2/hungary/2007) with accession number g ... | 2010 | 20931250 |
| a biochemical comparison of the in vivo effects of bulbine frutescens and bulbine natalensis on cutaneous wound healing. | in south africa the local population relies extensively on indigenous plants in the formulation of traditional medicines to treat skin ailments. the scientific merits of many of these plants used to treat wounds and burns are yet to be validated. bulbine natalensis and bulbine frutescens of the asphodelaceae family are indigenous to only southern africa and are widely used as a skin remedy. this study aimed to explore the scientific value of these plants through investigating the in vivo biochem ... | 2010 | 20937372 |
| next-generation sequencing of the trichinella murrelli mitochondrial genome allows comprehensive comparison of its divergence from the principal agent of human trichinellosis, trichinella spiralis. | the mitochondrial genome's non-recombinant mode of inheritance and relatively rapid rate of evolution has promoted its use as a marker for studying the biogeographic history and evolutionary interrelationships among many metazoan species. a modest portion of the mitochondrial genome has been defined for 12 species and genotypes of parasites in the genus trichinella, but its adequacy in representing the mitochondrial genome as a whole remains unclear, as the complete coding sequence has been char ... | 2010 | 20946970 |
| coronary bare metal stent implantation in homozygous ldl receptor deficient swine induces a neointimal formation pattern similar to humans. | to date, most of all new developments in stent technologies are tested in normal animals. although invaluable in the evaluation of device safety, the juvenile domestic swine (ds) do not follow the biological healing response occurring in humans following coronary stent implantation. by using a novel swine breed afflicted with familial hypercholesterolemia (fhs), we aimed to analyse the vascular response occurring following bare metal stent (bms) implantation by comparing in vivo endovascular ima ... | 2010 | 20950808 |
| magnetically controllable gastrointestinal steering of video capsules. | wireless capsule endoscopy (wce) allows for comfortable video explorations of the gastrointestinal (gi) tract, with special indication for the small bowel. in the other segments of the gi tract also accessible to probe gastroscopy and colonscopy, wce still exhibits poorer diagnostic efficacy. its main drawback is the impossibility of controlling the capsule movement, which is randomly driven by peristalsis and gravity. to solve this problem, magnetic maneuvering has recently become a thrust rese ... | 2010 | 20952324 |
| ochrobactrum pecoris sp. nov., isolated from farm animals. | two gram-negative, rod-shaped, non-spore-forming strains, 08rb2639(t) and 08rb2781-1 isolated from sheep (ovis aries) and boar (sus scrofa domestica), respectively, were studied for their taxonomic position. by 16s rrna gene sequencing, these strains revealed identical sequences and were shown to belong to the alphaproteobacteria with 97.8 % sequence similarity to ochrobactrum rhizosphaerae pr17(t), ochrobactrum pituitosum ccug 50899(t) , ochrobactrum tritici scii24(t) and ochrobactrum haematoph ... | 2010 | 20952542 |
| an elisa based on a truncated soluble orf2 protein for the detection of pcv2 antibodies in domestic pigs. | postweaning multisystemic wasting syndrome (pmws) is an important swine disease that is closely associated with porcine circovirus type 2 (pcv2). the capsid protein (cap protein) is a major structural protein that has at least three immunoreactive regions, and it can be a suitable candidate antigen for detecting the specific antibodies of a pcv2 infection. in the present study, an indirect enzyme-linked immunosorbent assay (tcelisa) based on a truncated soluble cap protein produced in escherichi ... | 2010 | 20960293 |
| left ventricular pacing lead insertion via the coronary sinus cardioplegia cannula: a novel method for temporary biventricular pacing during reoperative cardiac surgery. | objective: temporary biventricular pacing to treat low output states after cardiac surgery is an active area of investigation. reoperative cases are not studied due to adhesions, which preclude left ventricular mobilization to place epicardial pacing wires. in such patients, inserting a temporary left ventricular lead via the coronary sinus cardioplegia cannula may allow for biventricular pacing. we developed a novel technique for intraoperative left ventricular lead placement. methods: eight do ... | 2010 | 20965517 |
| african swine fever viruses with two different genotypes, both of which occur in domestic pigs, are associated with ticks and adult warthogs, respectively, at a single geographical site. | the role of the ancestral sylvatic cycle of the african swine fever virus (asfv) is not well understood in the endemic areas of eastern africa. we therefore analysed the asf infection status on samples collected from 51 free-ranging warthogs (phacocherus africanus) and 1576 ornithodorus porcinus ticks from 26 independent warthog burrows at a single ranch in kenya. abattoir samples from 83 domestic pigs without clinical symptoms, originating from specific locations with no recent reported asf out ... | 2010 | 20965989 |
| [changes in myocardial connexin 43 during ventricular fibrillation]. | to observe changes in connexin 43 (cx43) after ventricular fibrillation (vf) and the effects of rotigaptide (zp123) on cx43. | 2010 | 20977841 |
| a 6-bp deletion in the tyrp1 gene causes the brown colouration phenotype in chinese indigenous pigs. | brown coat colour has been described in chinese-tibetan, kele, and dahe pigs. here, we report the identification of a causal mutation underlying the brown colouration. we performed a genome-wide association study (gwas) on tibetan and kele pigs, and found that brown colours in chinese breeds are controlled by a single locus on pig chromosome 1. by using a haplotype-sharing analysis, we refined the critical region to a 1.5-mb interval that encompasses only one pigmentation gene: tyrosinase-relate ... | 2010 | 20978532 |
| virulence genes and plasmid profiles in rhodococcus equi isolates from domestic pigs and wild boars (sus scrofa) in brazil. | the virulence genes and plasmid profiles of 23 rhodococcus equi isolates from 258 lymph nodes from domestic pigs (129 nodes with lesions and 129 without lesions) and 120 lymph nodes from slaughtered wild boars (60 nodes with lesions and 60 without) were characterized. r. equi was obtained from 19 lymph nodes of domestic pigs, 17 with, and two without lesions, and from four lymph nodes with lesions, from wild boars. the 23 isolates were tested for the presence of vapa and vapb genes, responsible ... | 2010 | 20980033 |
| novel robotic da vinci instruments for laparoendoscopic single-site surgery. | to describe novel robotic laparoendoscopic single-site surgery (r-less) instruments, and present the initial laboratory experience in urology. | 2010 | 20980046 |
| comparative study of the osseointegration of dental implants after different bone augmentation techniques: vascularized femur flap, non-vascularized femur graft and mandibular bone graft. | objectives: the purpose of this study was to evaluate the osseointegration of the dental implants placed into the mandible augmented with different techniques in pigs. material and methods: four adult domestic pigs were used. horizontal augmentation of the mandible was performed in animals by using vascularized femur flap (vff), non-vascularized femur graft (nvfg) and monocortical mandibular block graft (mg). after 5 months of healing 10 dental implants were placed into each augmented site. the ... | 2010 | 21044163 |
| nucleotide variability of the porcine serpina6 gene and the origin of a putative causal mutation associated with meat quality. | the serpin peptidase inhibitor, clade a, member 6 gene (serpina6), also known as corticosteroid-binding globulin or cbg, is involved in obesity and stress sensitivity. previous studies have reported putative causal mutations within that gene in the porcine species. to characterize a hypothetical selective footprint, we have resequenced approximately 6 kb of coding and non-coding fragments in 20 pigs comprising domestic breeds and wild boars from asia and europe. nucleotide variability was found ... | 2010 | 21054451 |
| hybrid transureteral natural orifice translumenal endoscopic nephrectomy: a feasibility study in the porcine model. | natural orifice approaches for nephrectomy have included access via the stomach, vagina, bladder, and rectum. the use of the ureter as a natural orifice for natural orifice translumenal endoscopic surgery (notes) nephrectomy has not been previously reported. the purpose of this study is to test the feasibility of transureteral laparoscopic notes nephrectomy. | 2010 | 21058889 |
| noninvasive mr characterization of structural and functional components of reperfused infarct. | left ventricular (lv) remodeling is a highly complex phenomenon that starts soon after infarction and progresses to extensive regional and global architectural changes over time. | 2010 | 21062130 |
| genetic variations and sequences analysis of mtatp6 and mtatp8 genes among different chinese pig breeds. | to investigate the genetic variations of mtatp6 and mtatp8 genes among different chinese pig breeds, two fragments of 425 and 743 bp containing the whole coding region of mtatp8 and mtatp6 genes were amplified with 805 individuals from 23 chinese local pig breeds, three types of chinese wild boars and three european pig breeds. sequence comparison identified a total number of 17 substitutions including six variable sites in mtatp8 and eleven substitutions in mtatp6 gene. the restriction enzyme f ... | 2010 | 21077971 |
| prevalence of porcine circoviruses in transylvanian wild boars, detected by real-time pcr--short communication. | porcine circoviruses (pcv) are widespread in domestic pigs worldwide and there is growing information about the presence of pcv in other suid species. based on serological studies with sera of wild boars, it was established that pcv1 was present in these animals and antibodies specific to pcv2 were also detected in wild boars living in captivity or in sylvatic areas, both with or without clinical signs of pmws. studies including pcv2 genome or antigen detection confirmed the previous findings. t ... | 2010 | 21087917 |
| mechanical chest compressions with trapezoidal waveform improve haemodynamics during cardiac arrest. | during manual chest compressions for cardiac arrest the waveforms of chest compressions are generally sinusoidal, whereas mechanical chest compression devices can have different waveforms, including trapezoidal. we studied the haemodynamic differences of such waveforms in a porcine model of cardiac arrest. | 2010 | 21093141 |
| gene expression of serotonin and dopamine receptors and monoamine oxidase-a in the brain of dominant and subordinate pubertal domestic pigs (sus scrofa) fed a β-adrenoreceptor agonist. | aggression is a major source of social stress with negative effects on health and well-being, yet limited information is known about the molecular mechanisms mediating aggressive behavior in swine. ractopamine (rac) is a β-adrenoreceptor agonist that enhances growth but increases aggressive behaviors in female pigs. thus, the effects of rac, sex, and social rank on the mrna abundance of genes encoding serotonin and dopamine receptors, and monoamine oxidase (mao)-a in brains of sub-adult pigs wer ... | 2010 | 21094150 |
| an on-farm survey of spatial and temporal stratifications of 17β-estradiol concentrations. | 17β-estradiol (e2) is a natural estrogenic hormone found in animal manure and urine, which may cause endocrine disruption in sensitive organisms. 17β-estradiol has been widely detected in the environment, and animal agriculture may be an important source. the objectives of this study were to investigate the potential sources and/or spatial and temporal characteristics contributing to detections of e2 at the farm-scale. soil cores, segmented into 0.15m increments, were taken down to the water tab ... | 2010 | 21094971 |
| vertebral column, rib and sternal muscles of sulawesi babirusa (babyrousa celebensis). | the muscular anatomy of the vertebrae, ribs and sternebrae of the sulawesi babirusa (babyrousa celebensis) is described. there are many similarities to the anatomy of the domestic pig (sus scrofa). however, unlike other pigs, the m. spinalis et semispinalis cervicis et thoracis has an origin from the twelfth thoracic mamillary process. similarly, the babyrousa does not have the lumbar part of the m. obliquus internus abdominis which is found in other pigs. the m. sacrocaudalis dorsalis medialis ... | 2010 | 21108656 |
| first detection of african swine fever virus in ornithodoros porcinus in madagascar and new insights into tick distribution and taxonomy. | abstract: | 2010 | 21118485 |
| reassortant between human-like h3n2 and avian h5 subtype influenza a viruses in pigs: a potential public health risk. | human-like h3n2 influenza viruses have repeatedly been transmitted to domestic pigs in different regions of the world, but it is still uncertain whether any of these variants could become established in pig populations. the fact that different subtypes of influenza viruses have been detected in pigs makes them an ideal candidate for the genesis of a possible reassortant virus with both human and avian origins. however, the determination of whether pigs can act as a "mixing vessel" for a possible ... | 2010 | 20830295 |
| establishment of a porcine model for lobar lung auto-transplantation. | the aim of this study was to develop a porcine model of left single lung auto-transplantation. | 2010 | 20832588 |
| contrast-enhanced ultrasound for blunt hepatic trauma: an animal experiment. | the aim of this study was to study the value of contrast-enhanced ultrasound (ceus) in the diagnosis of active hemorrhage and intraparenchymal lesions in blunt hepatic trauma versus conventional ultrasound (us). | 2010 | 20837263 |
| camp-activated ca2+ signaling is required for cftr-mediated serous cell fluid secretion in porcine and human airways. | cystic fibrosis (cf), which is caused by mutations in cftr, affects many tissues, including the lung. submucosal gland serous acinar cells are primary sites of fluid secretion and cftr expression in the lung. absence of cftr in these cells may contribute to cf lung pathogenesis by disrupting fluid secretion. here, we have isolated primary serous acinar cells from wild-type and cftr-/- pigs and humans without cf to investigate the cellular mechanisms and regulation of fluid secretion by optical i ... | 2010 | 20739756 |
| a study on repair of porcine articular cartilage defects with tissue-engineered cartilage constructed in vivo by composite scaffold materials. | the study was performed to find out a promising injectable composite scaffold for cartilage tissue engineering. by using a composite of allogenous cartilage microparticle acellular tissue matrix (cmactm) and fibrin glue (fg) as injectable scaffold materials, tissue-engineered cartilage was constructed in vivo, and the effects of which on the repair of porcine articular cartilage defects were observed. cmactm was obtained from domestic pigs. the chondrocytes were prepared from experimental mini-t ... | 2010 | 20798625 |
| chondroitin sulfate demarcates astrocytic territories in the mammalian cerebral cortex. | adjacent astrocytes in the grey matter of the mammalian cerebral cortex are organized in a tile-like manner and separated from one another, forming discrete domains named "non-overlapping territories". we have previously reported that an anti-chondroitin sulfate (cs) antibody, cs-56, marks a subpopulation of cortical astrocytes which we named the dandelion clock-like structure (dacs) based on its morphological characteristics. in the present study, we found that another anti-cs antibody (anti-cs ... | 2010 | 20678547 |
| in vitro permeation of a pegylated naltrexone prodrug across microneedle-treated skin. | microneedles (mn) are a useful tool for increasing skin permeability to xenobiotics. previous research showed marked improvement in the percutaneous flux of naltrexone (ntx) hydrochloride by the use of mn skin pretreatment alone; however, for better therapeutic effect, further enhancement is desired. the goal of this in vitro study was to combine microneedle skin pretreatment with the use of a highly water-soluble pegylated naltrexone prodrug (polyethyleneglycol-ntx, peg-ntx) to investigate its ... | 2010 | 20678989 |
| comparative pathology of select agent influenza a virus infections. | influenza a virus infections may spread rapidly in human populations and cause variable mortality. two of these influenza viruses have been designated as select agents: 1918 h1n1 virus and highly pathogenic avian influenza (hpai) virus. knowledge of the pathology of these virus infections in humans, other naturally infected species, and experimental animals is important to understand the pathogenesis of influenza, to design appropriate models for evaluation of medical countermeasures, and to mak ... | 2010 | 20682805 |
| effect of continuous compressions and 30:2 cardiopulmonary resuscitation on global ventilation/perfusion values during resuscitation in a porcine model. | rescue ventilations during bystander resuscitation, although previously considered essential, interrupt the continuity of chest compressions and might have deleterious effects in basic life support. this study was undertaken to analyze the global ventilation/perfusion values of continuous compressions and 30:2 cardiopulmonary resuscitation to determine the effectiveness for each approach in a porcine model of prolonged bystander cardiopulmonary resuscitation for ventricular fibrillation. | 2010 | 20683258 |
| analysis of 11 tetrameric strs in wild boars for forensic purposes. | str profiling of animal species has a wide range of applications, including forensic identification, wildlife preservation, veterinary public health protection and food safety. we tested the efficacy of a multiplex pcr-based assay including 11 porcine-specific tetrameric strs in a population sample of wild boars (n=142) originating from piedmont (north west italy). multiple deviations from hardy-weinberg expectations were observed, mostly due to a reduction in observed heterozygosity indicative ... | 2010 | 20685189 |
| the rethink project--minipigs as models for the toxicity testing of new medicines and chemicals: an impact assessment. | the objective of the rethink project was to evaluate the potential impact of toxicity testing in the minipig as an alternative approach in regulatory toxicity testing that can contribute to the replacement, refinement and reduction of animal testing (3rs). minipigs are strains of domestic pigs that are markedly smaller than farmyard varieties, and thus better adapted to laboratory housing. the pig closely resembles man in many features of its anatomy, physiology, biochemistry and lifestyle. in p ... | 2010 | 20685395 |
| experimental study of pancreaticojejunostomy completed using anastomotic chains. | the most difficult, time-consuming, and complication-prone step in pancreaticoduodenectomy is the pancreaticojejunostomy step. the largest disadvantage of this kind of anastomosis is the high incidence of postoperative anastomotic leakage. once pancreatic leakage occurs, the patient death rate can be very high. the aim of this study was to design a pancreaticojejunostomy procedure using anastomotic chains, which results in the cut end of the jejunum being attached to the pancreatic stump without ... | 2010 | 20687743 |
| prevalence of actinobacillus pleuropneumoniae infection in hunted wild boars (sus scrofa) in germany. | actinobacillus pleuropneumoniae is an important pathogen of the porcine respiratory tract. subclinically and chronically infected pigs may enter a permanent carrier state, harboring a. pleuropneumoniae in lungs or tonsils. despite the enormous role of a. pleuropneumoniae in domestic swine production, no published data about prevalence and distribution of a. pleuropneumoniae infections in wild boars (sus scrofa) are available. antibodies against a. pleuropneumoniae have been detected in serum of ... | 2010 | 20688648 |
| a three-dimensional digital segmented and deformable brain atlas of the domestic pig. | we used high-magnetic field (4.7 t) magnetic resonance imaging (mri) to build the first high-resolution (100 microm x 150 microm x 100 microm) three-dimensional (3d) digital atlas in stereotaxic coordinates of the brain of a female domestic pig (sus scrofa domesticus). this atlas was constructed from one hemisphere which underwent a symmetrical transformation through the midsagittal plane. concomitant construction of a 3d histological atlas based on the same scheme facilitated control of deep br ... | 2010 | 20692291 |
| examination of protective effect of ischemic postconditioning after small bowel autotransplantation. | ischemia/reperfusion (i/r) injury is a serious condition that results from some surgical procedures, including intestinal transplantation. ischemic postconditioning is defined as brief periods of reperfusion alternating with reocclusion applied during the early minutes after reperfusion. the objective of this study was to investigate the effect of ischemic postconditioning before small bowel autotransplantation. total orthotopic intestinal autotransplantation was performed in 30 white domestic p ... | 2010 | 20692464 |
| anterior shear strength of the porcine lumbar spine after laminectomy and partial facetectomy. | degenerative lumbar spinal stenosis is the most common reason for lumbar surgery in patients in the age of 65 years and older. the standard surgical management is decompression of the spinal canal by laminectomy and partial facetectomy. the effect of this procedure on the shear strength of the spine has not yet been investigated in vitro. in the present study we determined the ultimate shear force to failure, the displacement and the shear stiffness after performing a laminectomy and a partial f ... | 2010 | 20582709 |
| depth of tissue ablation and residual thermal damage caused by a pixilated 2,940 nm laser in a swine skin model. | the purpose of this study was to assess the effects of fluence, pulse stacking, and multiple passes on the depth of injury caused by a fractionated er:yag laser in an in vivo farm pig model. design/material/methods: a fractionated 2,940 nm er:yag laser (pixel, alma lasers, caesarea, israel) was applied to the flank skin of a yorkshire cross pig. the 11 mmx11 mm handpiece was comprised of either 49 or 81 microbeams (200 microm diameter), depending on the tip configuration. there were six differen ... | 2010 | 20583246 |
| negative intratracheal pressure produced by esophageal detector devices causes tracheal wall collapse in a porcine cardiac arrest model. | esophageal detector devices (edds) impose negative pressure on the trachea or esophagus to verify endotracheal tube (ett) position. in cardiac arrest, the smooth muscle of the lower esophageal sphincter relaxes in a time-dependent and irreversible manner. if relaxation also occurs in the muscular posterior tracheal wall, it could predispose tracheal invagination or collapse with negative pressure, potentially yielding false-negative (tracheal ett, edd indicates esophagus) results. we compared 3 ... | 2010 | 20584869 |
| how pig sperm prepares to fertilize: stable acrosome docking to the plasma membrane. | mammalian sperms are activated in the oviduct. this process, which involves extensive sperm surface remodelling, is required for fertilization and can be mimicked under in vitro fertilization conditions (ivf). | 2010 | 20585455 |
| fourier domain pump-probe optical coherence tomography imaging of melanin. | we report the development of a two-color fourier domain pump-probe optical coherence tomography (ppoct) system. tissue phantom experiments to characterize the system performance demonstrated imaging depths in excess of 725 microm, nearly comparable to the base optical coherence tomography system. ppoct a-line rates were also demonstrated in excess of 1 khz. the physical origin of the ppoct signal was investigated with a series of experiments which revealed that the signal is a mixture of short a ... | 2010 | 20588366 |
| developmental stage-specific imprinting of ipl in domestic pigs (sus scrofa). | imprinted in placenta and liver (ipl) gene has been identified as an imprinted gene in the mouse and human. its sequence and imprinting status, however, have not been determined in the domestic pigs. in the present study, a 259 base pair-specific sequence for ipl gene of the domestic pig was obtained and a novel snp, a t/c transition, was identified in ipl exon 1. the c allele of this polymorphism was found to be the predominant allele in landrace,yorkshire, and duroc. the frequency of cc genoty ... | 2010 | 20589073 |
| endoscopic full-thickness resection and defect closure in the colon. | endoscopic full-thickness resection (eftr) is a minimally invasive method for en bloc resection of gi lesions. | 2010 | 20598252 |
| seroprevalence and risk factors associated with toxoplasma gondii in domestic pigs from spain. | serum samples from 2970 (1400 sows, 1570 fattening) pigs, from 100 farms in the 10 main swine production regions in spain were tested for antibodies against t. gondii by the modified agglutination test (mat). antibodies to t. gondii (mat 1:25 or higher) were detected in 492 pigs (16.6%, 9.7% in fattening pigs and 24.2% in sows). the herd prevalence was 85.0% (95% ci: 78-92) and within-farm prevalence ranged from 2.9% to 92.8% (median=17.6%). statistically significant differences were observed am ... | 2010 | 20601110 |
| different fusion configurations of evolutionarily conserved segments in karyotypes of potamochoerus porcus and phacochoerus africanus. | the karyotype of the red river hog potamochoerus porcus (2n = 34) differs from that of the domestic pig by the presence of 2 fusion chromosomes homologous to pig chromosomes 13/16 and 15/17. moreover, chromosomes corresponding to pig chromosomes 13/16 and 1 are both acrocentric. hybridization with region-specific painting probes confirmed tandem fusion of pig chromosomes 13 and 16, and a pericentric inversion of the pig chromosome 1p equivalent in p. porcus. the chromosome complement of the wart ... | 2010 | 20606389 |
| seeding endothelial progenitor cells on a self-expanding metal stent: an in vitro study. | to demonstrate the feasibility of seeding a self-expanding metal stent with endothelial progenitor cells to enhance rapid reendothelialization, which is postulated to prevent local thrombus formation and restenosis after vascular intervention. | 2010 | 20610181 |
| does pressure matter in creating burns in a porcine model? | multiple animal models of burn injury have been reported, and only some of these have been fully validated. one of the most popular approaches is burn infliction by direct contact with the heat source. previous investigators have reported that the pressure of application of the contact burn infliction device does not affect the depth of injury. we hypothesized that the depth of injury would increase with increasing pressure of application in a porcine burn model. forty mid-dermal contact burns m ... | 2010 | 20616654 |
| a role for factor xiia-mediated factor xi activation in thrombus formation in vivo. | mice lacking factor xii (fxii) or factor xi (fxi) are resistant to experimentally-induced thrombosis, suggesting fxiia activation of fxi contributes to thrombus formation in vivo. it is not clear whether this reaction has relevance for thrombosis in pri mates. in 2 carotid artery injury models (fecl(3) and rose bengal/laser), fxii-deficient mice are more resistant to thrombosis than fxi- or factor ix (fix)-deficient mice, raising the possibility that fxii and fxi function in distinct pathways. a ... | 2010 | 20634381 |
| micrornaome of porcine pre- and postnatal development. | the domestic pig is of enormous agricultural significance and valuable models for many human diseases. information concerning the pig micrornaome (mirnaome) has been long overdue and elucidation of this information will permit an atlas of microrna (mirna) regulation functions and networks to be constructed. here we performed a comprehensive search for porcine mirnas on ten small rna sequencing libraries prepared from a mixture of tissues obtained during the entire pig lifetime, from the fetal pe ... | 2010 | 20634961 |
| establishment of a streptozotocin-induced diabetic domestic pig model and a systematic evaluation of pathological changes in the hard and soft tissue over a 12-month period. | the number of diabetic patients in need of medical treatment is growing steadily. therefore, a diabetic animal model with high degree of similarities with humans, which is suitable for the systematic evaluation of biomaterials and medical devices, is needed. | 2010 | 20636725 |
| protection of the renal collecting system during radiofrequency ablation with antegrade cold dextrose infusion. | to evaluate the feasibility and efficacy of antegrade renal cooling during radiofrequency (rf) ablation to protect the renal collecting system in pigs. | 2010 | 20651062 |
| tetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viability. | the highly complex and unique mycobacterial cell wall is critical to the survival of mycobacteria in host cells. however, the biosynthetic pathways responsible for its synthesis are, in general, incompletely characterized. rv3802c from mycobacterium tuberculosis is a partially characterized phospholipase/thioesterase encoded within a genetic cluster dedicated to the synthesis of core structures of the mycobacterial cell wall, including mycolic acids and arabinogalactan. enzymatic assays performe ... | 2010 | 20656688 |
| the effects of rapid enzymatic debridement of deep partial-thickness burns with debrase on wound reepithelialization in swine. | reepithelialization of deep burns requires spontaneous or active removal or debridement of the necrotic eschar, as recently defined by the american burn association. debrase is a bromelain-derived enzymatic preparation that has been shown to result in rapid and selective debridement of human and animal burns. the authors hypothesized that rapid debridement of deep dermal burns with debrase would result in earlier reepithelialization of the remaining dermis in a porcine model. eighty deep dermal ... | 2010 | 20661148 |
| echo-endoscope biplane navigation system for endovascular aneurysm repair. | requirement of contrast medium limits the indication of endovascular intervention to patients with renal insufficiency and allergic reaction. furthermore, landmarks under fluoroscopic guidance do not necessarily encompass the local anatomy of complex aortic lesions. we evaluated the feasibility of a bimodal monitoring system consisting of echocardiography and endoscopy as a more accurate anatomical navigation system for endovascular intervention. | 2010 | 20667361 |
| a tractable experimental model for study of human and animal scabies. | scabies is a parasitic skin infestation caused by the burrowing mite sarcoptes scabiei. it is common worldwide and spreads rapidly under crowded conditions, such as those found in socially disadvantaged communities of indigenous populations and in developing countries. pruritic scabies lesions facilitate opportunistic bacterial infections, particularly group a streptococci. streptococcal infections cause significant sequelae and the increased community streptococcal burden has led to extreme lev ... | 2010 | 20668508 |
| phylogenetic analysis of classical swine fever virus isolates from peru. | classical swine fever (csf) is considered to be endemic in peru with outbreaks reported to the world organization for animal health as recently as 2008 and 2009. nevertheless, little is known regarding the genetic subgroup(s) of csf virus that are circulating in peru or their relationship to recent csf viruses that have been isolated from neighbouring south american countries or other parts of the world. in this study, we molecularly characterize csf viruses that were isolated from domestic pigs ... | 2010 | 20545910 |
| carbon dioxide-enhanced ct-guided placement of aortic stent-grafts: feasibility in an animal model. | to test the feasibility of carbon dioxide (co(2))-enhanced computed tomography (ct)-guided placement of infrarenal abdominal aortic stent-grafts in an animal model. | 2010 | 20557172 |
| hypoxia-inducible factor 1-alpha release after intracoronary versus intramyocardial stem cell therapy in myocardial infarction. | we have investigated the effect of stem cell delivery on the release of hypoxia-inducible factor 1 alpha (hif-1alpha) in peripheral circulation and myocardium in experimental myocardial ischemia. closed-chest, reperfused myocardial infarction (mi) was created in domestic pigs. porcine mesenchymal stem cells (mscs) were cultured and delivered (9.8 +/- 1.2 x 10(6)) either percutaneously noga-guided transendocardially (group im) or intracoronary (group ic) 22 +/- 4 days post-mi. pigs without msc de ... | 2010 | 20560024 |
| familial hypercholesterolaemic downsized pig with human-like coronary atherosclerosis: a model for preclinical studies. | a manageable and reproducible large animal model of human-like coronary atherosclerosis is lacking but highly needed for translational research in percutaneous coronary interventions and imaging. farm pigs with familial hypercholesterolaemia develop advanced atherosclerosis in two to three years but then weigh >200 kg making them impractical and costly. we aimed at down-sizing this pig and accelerating coronary plaque development to make the model more useful and affordable. | 2010 | 20562079 |
| classical swine fever virus in south-eastern europe--retrospective analysis of the disease situation and molecular epidemiology. | classical swine fever (csf) is among the most important diseases of domestic pigs and causes great socio-economic losses. therefore, control of csf is given high priority within the european union, including financial support of concerted control actions in candidate and in potential candidate countries. unfortunately, from some of these countries information on the csf situation and related data is very limited. this study was undertaken to gather all available information on the domestic pig p ... | 2010 | 20541876 |
| analysis of the non-recombining y chromosome defines polymorphisms in domestic pig breeds: ancestral bases identified by comparative sequencing. | sequences from 20 amplicons representing nine different loci and 11369bp from the short arm of the pig y chromosome were compared using pools of dna from different european and chinese breeds. a total of 33 polymorphic sites were identified, including five indels and 28 single nucleotide polymorphisms (snps). three high frequency snps within the coding regions of sry were further analysed across 889 males representing 25 european and 25 asian breeds or lines, plus a european line of meishan. two ... | 2010 | 20477804 |
| dietary consistency and the midline sutures in growing pigs. | the purpose of this study was to investigate the effects of reduced masticatory function on midline suture growth and morphology in growing pigs. | 2010 | 20477970 |
| [hepatitis e--a new zoonotic disease in germany?]. | hepatitis e virus (hev) is the most frequent pathogen of a fecal-oral transmitted hepatitis in humans in many developing countries. it is endemic in the middle east, in india, in southeast asia, central asia as well as in central and south america. it can be predominantly found in young adults. the mortality rate comes up to 2% whereas in pregnant women death rate can reach about 25%. until a few years ago, acute hepatitis e was thought to be rare in industrialized countries: most cases were fou ... | 2010 | 20496825 |
| an animal model for sinus floor elevation with great elevation heights. macroscopic, microscopic, radiological and micro-ct analysis: ex vivo. | different animal models are used for research and training concerning sinus floor elevation. however, there is little information regarding an animal model for elevation heights of approximately 10 mm. the aim of this study was to explore the anatomical aspects of the maxillary sinus of adult pigs and to investigate the suitability of this animal as a model for sinus floor elevation training and research with great elevation heights. | 2010 | 20497438 |
| cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: implications for clinical trials. | abstract : introduction : early randomized clinical trials of autologous bone marrow cardiac stem cell therapy have reported contradictory results highlighting the need for a better evaluation of protocol designs. this study was designed to quantify and compare whole body and heart cell distribution after intracoronary or peripheral intravenous injection of autologous bone marrow mononuclear cells in a porcine acute myocardial infarction model with late reperfusion. methods : myocardial infarcti ... | 2010 | 20504285 |
| molecular and serological survey of hepatitis e virus infection among domestic pigs in inner mongolia, china. | to evaluate the prevalence and characteristics of swine hepatitis e virus (hev) infection in inner mongolia, china, serum samples obtained from 356 2- to 4-month-old pigs on 14 farms in inner mongolia were tested for the presence of anti-hev antibodies and hev rna. overall, 186 pigs (52%) tested positive for anti-hev antibodies, while 30 pigs (8%) had detectable hev rna levels. the 30 hev isolates recovered from the viremic pigs were phylogenetically classified into genotype 4 and differed from ... | 2010 | 20512514 |
| rethinking cull boar transport. | 2010 | 20514259 | |
| avian influenza vaccination in chickens and pigs with replication-competent adenovirus-free human recombinant adenovirus 5. | protective immunity to avian influenza (ai) virus can be elicited in chickens by in ovo or intramuscular vaccination with replication-competent adenovirus (rca)-free human recombinant adenovirus serotype 5 (ad5) encoding ai virus h5 (adtw68.h5) or h7 (adcn94.h7) hemagglutinins. we evaluated bivalent in ovo vaccination with adtw68.h5 and adcn94.h7 and determined that vaccinated chickens developed robust hemagglutination inhibition (hi) antibody levels to both h5 and h7 ai strains. additionally, w ... | 2010 | 20521636 |
| chitosan arrests bleeding in major hepatic injuries with clotting dysfunction: an in vivo experimental study in a model of hepatic injury in the presence of moderate systemic heparinisation. | the purpose of this study was to explore the effectiveness of two chitosan formulations, omni-stat® granules and celox gauze®, in a model of major hepatic injury in the presence of clotting dysfunction. | 2010 | 20522310 |
| iron chelation for amelioration of liver ischemia-reperfusion injury. | liver resections are frequently associated with significant ischemia-reperfusion (i-r) injury of the liver remnant. the aim of this study was to investigate whether deferoxamine (dfo) can ameliorate i-r injury during major hepatectomies performed under vascular exclusion of the liver in a porcine model. twelve female domestic pigs were divided into control (n = 6) and dfo treatment (n = 6) groups and subjected to 150 min. liver ischemia followed by 70% hepatectomy and 24 hours reperfusion. pigs ... | 2010 | 20524816 |
| laser-induced thermotherapy (litt)--evaluation of a miniaturised applicator and implementation in a 1.0-t high-field open mri applying a porcine liver model. | to evaluate the feasibility and safety of a novel litt applicator for thermal ablation of liver malignancies in 1.0-t high-field open mri. | 2010 | 20526885 |
| a long arm for ultrasound: a combined robotic focused ultrasound setup for magnetic resonance-guided focused ultrasound surgery. | focused ultrasound surgery (fus) is a highly precise noninvasive procedure to ablate pathogenic tissue. fus therapy is often combined with magnetic resonance (mr) imaging as mr imaging offers excellent target identification and allows for continuous monitoring of fus induced temperature changes. as the dimensions of the ultrasound (us) focus are typically much smaller than the targeted volume, multiple sonications and focus repositioning are interleaved to scan the focus over the target volume. ... | 2010 | 20527572 |
| gastric lymphatic basin dissection for sentinel node biopsy using hybrid natural orifice transluminal endoscopic surgery (notes). | the aim of the present study was to describe a method of gastric lymphatic basin dissection for sentinel node biopsy using natural orifice transluminal endoscopic surgery with laparoscopic assistance (hybrid notes) in a porcine model. lymph node dissection was performed in three healthy female domestic farm pigs (each around 40 kg) between october, 2007, and december, 2007. the pigs were administered a general anesthetic and laparoscopy-guided transvaginal colpotomy was performed. a two-channel ... | 2010 | 20528682 |
| a new surgical trainer (bopt) improves skill transfer for anastomotic techniques in gastrointestinal surgery into the operating room: a prospective randomized trial. | a multifunctional skill trainer (berlin operation trainer, bopt) allows realistic training of conventional gastrointestinal (gi) surgical techniques. the aim of this prospective randomized study was to evaluate the training success and the potential for transfer of anastomotic techniques in gi surgery into the operating room using the bopt. | 2010 | 20533037 |
| pathomorphological changes after radiofrequency ablation in the liver. | radiofrequency ablation (rfa) has become a widespread treatment option for liver carcinoma. there is limited knowledge regarding the macroscopic and histomorphological changes of induced lesions. twelve domestic pigs underwent rfa using a starburst xl device with ablation diameter of 3 cm. one animal died within 24 h, two animals were killed after 2 weeks, and nine after 4 weeks. their livers were used for macroscopic and histological investigation. six human liver resection specimens after prev ... | 2010 | 20403040 |
| patterns of east asian pig domestication, migration, and turnover revealed by modern and ancient dna. | the establishment of agricultural economies based upon domestic animals began independently in many parts of the world and led to both increases in human population size and the migration of people carrying domestic plants and animals. the precise circumstances of the earliest phases of these events remain mysterious given their antiquity and the fact that subsequent waves of migrants have often replaced the first. through the use of more than 1,500 modern (including 151 previously uncharacteriz ... | 2010 | 20404179 |
| light microscopic, electron microscopic, and immunohistochemical comparison of bama minipig (sus scrofa domestica) and human skin. | here we sought to evaluate the possibility of using chinese bama miniature pig skin as a suitable animal model for human skin. morphologic features of the skin of bama miniature pigs resemble those of human skin, including skin layer thickness, development of a superficial vascular system, structure of the dermal-epidermal interface, and extracellular matrix. the characteristics and densities of langerhans cells, fibroblasts, vascular endothelial cells, and mast cells were similar between bama p ... | 2010 | 20412690 |
| influence of the lung mechanical ventilation with injurious parameters on 7-ketocholesterol synthesis in sus scrofa. | the aim of work was to investigate changes of 7-ketocholesterol synthesis in alveolar macrophages in the dynamic of lung mechanical ventilation with injurious parameters. the goal of in vitro part of work was to observe influence of 7-ketocholesterol on inos and mip1 beta production in bronchoalveolar lavage fluid (balf) cells. we used 17 healthy domestic pigs randomly assigned into two treatment groups: group i with mechanical ventilation with physiological parameters; group || underwent injuri ... | 2010 | 20423610 |
| temporal distribution of ten calyptrate dipteran species of medicolegal importance in rio de janeiro, brazil. | brazilian studies involving entomological succession patterns in carcasses have been used to describe the necrophagous entomofauna of a determined municipality or region with forensic objectives. following the same objectives, an ecological study with 10 calyptrate dipterans was carried out during the winter of 2007 and the summer of 2008 in the metropolitan region of the municipality of rio de janeiro. the aim of this study was to describe several aspects of the phenology of these species in th ... | 2010 | 20428680 |
| correlation of right ventricular dysfunction parameters and pulmonary vascular obstruction score in acute pulmonary embolism in a porcine model. | this paper aims to non-invasively determine right ventricular dysfunction parameters (rvdp) in acute pulmonary embolism (ape) and to correlate these parameters with a computed tomography (ct)-based pulmonary artery obstruction score (os). in seven domestic pigs, magnetic resonance imaging (mri) was performed before (n = 7) and after (n = 5) ape was induced. analysis of relative changes in right ventricular stroke volume (rvsv%), output (rvo%), end-systolic (rvesv%), end-diastolic volume (rvedv%) ... | 2010 | 20428913 |
| endoscopic mucosal resection using a grasp-and-snare technique. | endoscopic mucosal resection (emr) is a minimally invasive method for en bloc removal of superficial gastrointestinal lesions. the aim of this study was to evaluate the feasibility of a novel grasp-and-snare emr technique. | 2010 | 20432205 |
| diffuse reflectance spectroscopy for optical soft tissue differentiation as remote feedback control for tissue-specific laser surgery. | laser surgery does not provide haptic feedback for operating layer-by-layer and thereby preserving vulnerable anatomical structures like nerve tissue or blood vessels. diffuse reflectance spectra can facilitate remote optical tissue differentiation. it is the aim of the study to use this technique on soft tissue samples, to set a technological basis for a remote optical feedback system for tissue-specific laser surgery. | 2010 | 20432281 |
| a study of alternative splicing in the pig. | abstract: | 2010 | 20444244 |
| variation of aujeszky's disease viruses in wild swine in usa. | in the united states of america, aujeszky's disease (pseudorabies) has been eradicated from all domestic swine. some re-emergence of infection occurred as vaccine use diminished. sporadic outbreaks have also occurred because of the reservoir of infection in feral swine that have spread across the southern two-thirds of the country and hawaii. in order to be able to understand the origins of re-emerging virus, sequence analysis of variable genes in pseudorabies virus (prv) has been used to differ ... | 2010 | 20444559 |
| pure "cable-tie partial nephrectomy": a porcine model. | the standard surgical procedure for polar renal tumors is nephron-sparing surgery, currently performed laparoscopically in most cases. this technically challenging surgery involves clamping of the hilar vessels and warm kidney ischemia. this study tested the feasibility of performing polar nephrectomy using a cable tie without hilar clamping or any other hemostatic procedure. | 2010 | 20445994 |
| high prevalence of anti-trichinella igg in domestic pigs of the son la province, vietnam. | although several outbreaks of trichinella infection among humans have occurred in northwestern vietnam, no information is available on the circulation of trichinella among domestic pigs. the objective of the present study was to estimate the seroprevalence of anti-trichinella igg in free-roaming pigs (sus scrofa) in the son la province of northwestern vietnam, where a human outbreak of trichinellosis occurred in june 2008. serum samples were collected from free-roaming pigs of four communes of t ... | 2010 | 19962244 |
| a study to demonstrate freedom from trichinella spp. in domestic pigs in switzerland. | trichinellosis is a food-borne zoonotic disease caused by the nematode trichinella spp. many omnivorous and carnivorous animal species can act as host for this parasite, including domestic pigs. to protect public health, it should be ensured that pork should not contain infective trichinella larvae. surveillance for trichinella spp. can be done using direct (larval detection) and indirect (antibody detection) diagnostic techniques. the aim of this study was to demonstrate the absence of infectio ... | 2010 | 19968841 |
| experimental infection of pigs with border disease virus isolated from pyrenean chamois (rupicapra pyrenaica). | between 2001 and 2007, several outbreaks of disease associated with border disease virus (bdv) infection were reported in the central pyrenees (northeast spain) and were associated with a major reduction in chamois (rupicapra pyrenaica) populations. at the same time, wild boars (sus scrofa) from the same area were found to be seropositive to this pestivirus, without showing clinical signs. the present study examines the susceptibility of domestic swine and the course of the infection with a bdv ... | 2010 | 20453208 |
| detection of porcine circovirus in rodents - short communication. | porcine circoviruses (pcv) are present worldwide, infecting domestic pigs and wild boars alike. studies under laboratory conditions indicated that pcv can be taken up by mice and the virus can replicate in these animals. the possible role of rodents in maintaining and transmitting pcv2 infection in the field has not been investigated yet. the present study reports the detection of pcv2, the pathogenic form of the virus, in mice and rats. a number of rodents, such as mice, rats and voles, were co ... | 2010 | 20460225 |
| early atherosclerosis aggravates the effect of renal artery stenosis on the swine kidney. | atherosclerotic renal artery stenosis (aras) is increasingly identified in patients with end-stage renal disease. renal function in aras patients deteriorates more frequently than in nonatherosclerotic renal artery stenosis (ras). this study was designed to test the hypothesis that atherosclerosis modifies the relationship between single-kidney hemodynamics and function and the severity of stenosis. the degree of unilateral ras in domestic pigs (4 normal, 26 ras, and 22 aras) was correlated with ... | 2010 | 20462971 |