Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [morphological studies for invasion and intracellular growth of f. tularensis in cultured cells (author's transl)]. | 1981 | 7345173 | |
| serologic survey for selected microbial agents in mammals from alberta, 1976. | blood samples were taken from humans and several species of free-ranging wild mammals from five different geographic areas of alberta, canada. sera were tested for antibody to eastern equine encephalitis (eee) virus, western equine encephalitis (wee) virus, st. louis encephalitis (sle) virus, powassan (pow) virus, the snowshoe hare (ssh) strain of the california group (cal) of viruses, northway (nor) virus, klamath (kla) virus, infectious bovine rhinotracheitis (ibr) virus, and two bacteria, bru ... | 1981 | 6273600 |
| bacterial immunizations. | 1980 | 6766272 | |
| glucose and alanine metabolism during bacterial infections in rats and rhesus monkeys. | to investigate the effects of bacterial infection on glucose and alanine metabolism, a variety of studies were carried out in rat and monkey models. these included glucose turnover by a pulse-dose technique in infected rats; alanine and glucose production and utilization in control and septic monkeys; in vivo measurement of gluconeogenesis in rats, with and without an alanine load; the in vitro rate of glucose formation from various substrates by isolated liver perfusion and hepatic cells; and i ... | 1980 | 6768954 |
| [current status of vaccine treatment of zoonotic infections]. | 1980 | 6776687 | |
| [characteristics of microbial multiplication in parenterally infected xenopsylla cheopis (siphonaptera) fleas]. | being inoculated parenterally various microbes cause the fleas x. cheopis a stable infection which, as a rule, is preserved in experimental insects to the end of life. reproducing intensively listeria monocytogenes and salmonella typhimurium caused the death of all ectoparasites in 3 to 5 days. the increase in abundance of escherichia coli, yersinia pseudotuberculosis, y. enterocolitica and vaccine strains of y. pestis "ev" and francisella tularensis went on gradually and infected fleas lived up ... | 1980 | 6780964 |
| treatment of tularemia, including pulmonary tularemia, with gentamicin. | an alternative to streptomycin for treatment of possible tularemia would be useful on occasions when a patient develops a perplexing pneumonia that does not respond to initial treatment. in geographic areas where tularemia is endemic, an antimicrobial drug that is bactericidal for francisella tularensis and is also effective against a spectrum of common pulmonary pathogens, including the enterobacteriaceae and most strains of pseudomonas aeruginosa, would be desirable. the purposes of this repor ... | 1980 | 7352712 |
| cross-reaction to legionella pneumophila antigen in sera with elevated titers to pseudomonas pseudomallei. | a significantly greater incidence (p less than 0.005) of legionella pneumophila microagglutination titers greater than or equal to 32 was found in sera with elevated titers to pseudomonas pseudomallei as compared with sera with negative titers for p. pseudomallei antibodies. the greater incidence of l. pneumophila titers in these sera suggests that l. pneumophila and p. pseudomallei share an antigen. the incidence of l. pneumophila microagglutination titers of greater than or equal to 32 in sera ... | 1980 | 7354127 |
| [characteristics of the tularemia prevention measures in the natural foci of the carpathian region]. | 1980 | 7376572 | |
| host resistance to tick-borne pathogens by virtue of resistance to tick infestation. | 1980 | 7377869 | |
| [cross immunity to plague and tularemia]. | 1980 | 7395403 | |
| [method of detecting bacteriocins in the agent of tularemia]. | 1980 | 7415670 | |
| mechanisms of protective immunogenicity of microbial vaccines: effects of cyclophosphamide pretreatment in venezuelan encephalitis, q fever and tularaemia. | administration of high-dose (250 mg/kg) cyclophosphamide (cy) to guinea-pigs and mice 3 days prior to immunization with inactivated vaccine derived from venezuelan encephalitis virus (ve), coxiella burnetii and francisella tularensis resulted in accentuated and prolonged delayed-type hypersensitivity (dth) and in vitro cellular immunity (cmi) to specific antigen. humoral antibody were either absent or significantly lower in cy-pretreated animals compared to immunized non-pretreated controls. cy ... | 1980 | 7438552 |
| glucan-induced enhancement of host resistance to selected infectious diseases. | we conducted studies with mice, rats, and monkeys which demonstrated the ability of glucan to induce either nonspecific or specific enhancement of host resistance to infectious diseases. intravenous pretreatment of mice with glucan significantly enhanced the survival of mice challenged with either venezuelan equine encephalomyelitis (vee) virus or rift valley fever virus. pretreatment was beneficial when initiated 3 days before challenge with vee virus and 7 days before challenge with rift valle ... | 1980 | 7439978 |
| [examination of a natural tularemia focus in the crimea using a passive hemagglutination reaction system]. | 1980 | 6445649 | |
| [biological properties of the strains f. tularensis isolated in slovakia (author's transl)]. | 1980 | 6448103 | |
| [isolation of the causative agent of tularemia from an inoculum from skin lesions in the ulcerobubonic form of the disease]. | a case of tularemia in a human patient infected through the sting of a gadfly (tabanus) is described. the causative agent of the disease was isolated from the patient with the ulcerobubonic form of the disease by the method of the direct inoculation of the contents of the patient's cutaneous effect. the properties of the isolated culture were established; the strain thus obtained was classified as a representative of the geographical race francisella tularensis holarctica 01s. the causative agen ... | 1980 | 6449122 |
| [development of a serological micromethod for the detection of antibodies against francisella tularensis]. | 1980 | 6982628 | |
| a probable endocrine basis for the depression of ketone bodies during infectious or inflammatory state in rats. | the effects of infection with streptococcus pneumoniae, francisella tularensis, and venezuelan equine encephalitis virus as well as inflammatory stress induced by the administration of turpentine and endotoxin on plasma ketone bodies and insulin were studied in white rats. all of the infectious/inflammatory stresses caused a significant decrease in the ketonemia of fasting and an elevation of plasma insulin. when a pneumococcal infection was initiated in a diabetic rat, inhibition of fasting ket ... | 1980 | 6993191 |
| [technic of studying microorganism viability in a simulated aerosol state on fiberglass microfilaments]. | a specially developed method of studying the viability of microorganisms in the simulated aerosol state on glass microfibers was used to show that the survival rate of e. coli and f. tularensis on fiber-glass spheres was similar to that in true aerosol, as observed in a static aerosol chamber. the proposed method allows to study the viability of microbial cells after prolonged existence in aerosol under any environmental condition both in open spaces and closed rooms. | 1980 | 7001815 |
| cell-mediated immunity against francisella tularensis after natural infection. | 31 subjects with tularemia recently or up to 11 years earlier were studied for cell-mediated immunity against francisella tularensis using formalin-killed bacteria as antigen in the lymphocyte blast transformation test. lymphocytes from all the subjects responded to f. tularensis antigen both in separated mononuclear cell and whole blood cultures, whereas lymphocytes from 12 controls responded not at all or only weakly to hig antigen concentrations and only in separated mononuclear cell cultures ... | 1980 | 7006062 |
| influence of complement on the chemiluminescent response of human leukocytes to immune complex. | vaccine bacteria of francisella tularensis were mixed with human serum containing specific antibodies against the same organism, and the mixture was incubated at 37 degrees c for 30 min. the mixture induced a two-peak chemiluminescent response in polymorphonuclear leukocytes. the initial peak was induced by a soluble agent, formed during incubation. the formation of this agent involved the activation of complement component c5. the second peak of the chemiluminescent response was induced by the ... | 1980 | 7011971 |
| sensitivity to macrolide antibiotics and lincomycin in francisella tularensis holarctica. | among the 345 f. tularensis holarctica strains isolated in europe, asia and north america, two variants were found: one sensitive and the other resistant to erythromycin, oleandomycin and lincomycin. these characteristics were not associated with virulence, antigenicity, biochemical activity or source of isolation and displayed high stability in passages in laboratory animals or multiple passages in culture media. the two variants are proposed to be designated as biotype (biovar) i, erythromycin ... | 1980 | 7190590 |
| detection of enzootic territories and exploration of tularemia epizootics in different types of natural foci of this infection by serological examination of bird pellets and the excrements of beasts of prey. | serological analysis (reaction of antibody neutralization) of pellets of birds and excrements of beasts of prey for the presence of tularemia microbe antigen is an efficient method of detection and investigation of epizootics in all types of natural foci of the infection and also for the exploration of new focal territories. the method permits with small expenditure of labour and within a short time, to collect material characterizing the epizootic process on a large territory. tularemia epizoot ... | 1980 | 7190592 |
| demonstration of opsonizing antibodies to francisella tularensis by leukocyte chemiluminescence. | twenty-three individuals were vaccinated with a viable attenuated strain of francisella tularensis, and blood was collected at various time intervals during 4 weeks. to demonstrate opsonizing antibodies, a mixture of serum and vaccine bacteria was incubated, whereafter the chemiluminescence response of polymorphonuclear (pmn) leukocytes to this mixture was recorded. no opsonizing antibodies against f. tularensis were found in sera obtained before vaccination. eleven days after vaccination, sera ... | 1980 | 7216416 |
| differential alterations in host peripheral polymorphonuclear leukocyte chemiluminescence during the course of bacterial and viral infections. | previous studies have shown that stimulation of the oxidative metabolism in polymorphonuclear leukocytes (pmn) by in vitro phagocytosis of various microorganisms results in photon emission, termed chemiluminescence (cl). studies were conducted to determine whether bacterial and viral infections induce enhanced basal endogenous host peripheral pmn cl in the absence of in vitro phagocytic stimulation. nonimmune rats and guinea pigs as well as immune rats were inoculated with various doses (10(5) t ... | 1980 | 7228389 |
| antigenic composition of a vaccine strain of francisella tularensis. | the antigenic composition of the live vaccine strain of francisella tularensis was investigated. ether-water extracts, water-soluble material from freeze-pressed bacteria and detergent-eluted material from bacterial envelope were allowed to react in immunodiffusion and immunoelectrophoresis with rabbit antiserum against disintegrated bacteria of the vaccine strain. ten antigenic factors were distinguished in an ether extract. when the extract was precipitated with ammonium sulphate 15 antigenic ... | 1980 | 6153169 |
| evaluation of a safranin-o-stained antigen microagglutination test for francisella tularensis antibodies. | a microagglutination test for francisella tularensis, with 0.025-ml amounts of diluted sera and 0.025-ml amounts of safranin-o-stained antigen in u-bottom microtitration plates, was compared with a tube agglutination test by using 137 sera. there was 86.3% agreement (+/- 1 dilution variation) between the microagglutination results and the tube agglutination results for sera with tube agglutination titers of greater than or equal to 20. there was 100% agreement (+/- 1 dilution variation) for sera ... | 1980 | 6153660 |
| [survival capacity of certain pathogens under environmental conditions]. | 1979 | 103703 | |
| tularemia in a group of nonhuman primates. | in an episode of tularemia in a canadian zoologic garden, three black and red tamarins (sanguinus nigricollis) and one talapoin (cercopithecus talapoin) died. a second talapoin developed abscesses in the tongue and submandibular area; this animal recovered with treatment. francisella tularensis was isolated from lung, liver, and spleen from each dead monkey and from pus collected from the tongue abscess of the sick talapoin. the attending veterinarian contracted the disease from a tamarin bite. ... | 1979 | 118145 |
| human tularemia at an urban zoo. | 1979 | 120758 | |
| enzyme-linked immunosorbent assay for immunological diagnosis of human tularemia. | the enzyme-linked immunosorbent assay (elisa) was applied for immunological diagnosis of human tularemia, using lipopolysaccharide from francisella tularensis as antigen. sera collected from patients, healthy individuals, and vaccinated volunteers were investigated for antibodies against f. tularensis by elisa and tube agglutination. in elisa all sera were titrated with a polyspecific anti-immunoglobulin enzyme conjugate. a limited number of consecutive sera from individual patients were also in ... | 1979 | 120873 |
| [bactericidal effect of peracetic acid on francisella tularensis (author's transl)]. | 1979 | 156076 | |
| isolation of francisella tularensis from mites haemogamasus nidi and laelaps hilaris in western slovakia. | isolating of f. tularensis from gamasid mites h. nidi parasitizing on the bank vole (cl. glareolus) and l. hilaris on the common vole (m. arvalis) are reported. the epidemiological significance of this finding is discussed. | 1979 | 388944 |
| isolation of pathogens other than yersinia pestis during plague investigations. | from 1975 to 1978, 37 isolates of pasteurella multocida, 1 of salmonella enteriditis, and 5 of francisella tularensis were recovered from 42 mammalian specimens and 1 flea pool submitted for examination for evidence of infection with yersinia pestis. most of the specimens were collected during investigations of either a human plague infection or a reported epizootic among rodent populations. all specimens were of species regularly or occasionally involved in plague or tularemia cycles in nature ... | 1979 | 392123 |
| clinical, epidemiological and therapeutical experience with human tularaemia: the role of hamster hunters. | fifty patients suffering from tularaemia were treated in our department. the most frequent occupation of the tularaemia patients was hamster hunter. the most important source of the tularaemic infection (90%) was the hamster (cricetus cricetus). we observed the cutano-glandular form in 90% of the patients and internal tularaemia in 10%. the antibiotics used (streptomycin i. m., oxytetracycline and doxycycline per os) were effective. | 1979 | 437894 |
| pneumonic tularemia on martha's vineyard. | 1979 | 481515 | |
| resistance to tick-borne francisella tularensis by tick-sensitized rabbits: allergic klendusity. | mammals become hypersensitive to ticks that feed upon them. that hypersensitivity was thought responsible for an observation that a large number of francisella tularensis-infected dermacentor variabilis failed to infect a rabbit previously exposed to ticks of that species. in a series of tests of that hypothesis, rabbits sensitized to ticks were often significantly more resistant than control animals to tick-borne tularemia. the conditions that determine the klendusity are thought to be variable ... | 1979 | 484770 |
| tuleremia in the raven (corvus corax). | 1979 | 492969 | |
| role of the liver in regulation of ketone body production during sepsis. | during caloric deprivation, the septic host may fail to develop ketonemia as an adaptation to starvation. because the plasma ketone body concentration is a function of the ratio of hepatic production and peripheral usage, a pneumococcal sepsis model was used in rats to measure the complex metabolic events that could account for this failure, including the effects of infection on lipolysis and esterification in adipose tissue, fatty acid transport in plasma and the rates of hepatic ketogenesis an ... | 1979 | 500825 |
| [present-day problems of natural foci and the prevention of tularemia]. | 1979 | 506600 | |
| [further study of a natural focus of tularemia on biriuchiĭ island]. | 1979 | 516954 | |
| time of lymphocyte response after onset of tularemia and after tularemia vaccination. | blood lymphocytes were prepared from 6 patients at various time intervals after the onset of tularemia and from 10 subjects after vaccination against this disease. lymphocytes were also prepared from subjects who had been vaccinated 1 and 2 years previously. the lymphocytes were incubated in the presence of membranes of the vaccine strain. lymphocytes obtained 2 weeks or later after onset of the disease responded to the membranes with increased deoxyribonucleic acid synthesis, whereas lymphocyte ... | 1979 | 521485 |
| cellular fatty acid composition of francisella tularensis. | several unusual fatty acids characterized strains of francisella tularensis. long-chain (c20-c26) acids and the hydroxy acids 2-hydroxy-decanoate, 3-hydroxy-hexadecanoate, and 3-hydroxy-octadecanoate appeared to be of special diagnostic value. | 1979 | 521490 |
| tularemia pneumonia in washington, dc. a report of three cases with possible common-source exposures. | in june 1978, three cases of tularemia pneumonia occurred in persons residing in the washington, dc, area. the patients, all men, became ill three to four days after a brief session training their hunting dogs in an undeveloped wooded area adjacent to a housing complex. one of the dogs, which later died, had captured a wild rabbit during the training session. all three men had handled the rabbit while familiarizing their dogs with the rabbit's scent. the men had no other common exposure that was ... | 1979 | 573806 |
| persistence of enterobacteriaceae in female adults of the biting gnat culicoides variipennis (diptera: ceratopogonidae). | 1978 | 344884 | |
| [protective reaction in ornithodoros papillipes to the causative agents of salmonellosis and tularemia and to staphylococcus]. | 1978 | 356412 | |
| [mechanism of the changes in the animal reactivity to tularemia in mixed infection]. | experiments were conducted on albino rats infected with listeria or salmonelloses, and then with tularemia; differences were revealed in the duration of manifestation of nonspecific resistance associated with peculiarities of pathogenesis and immunogenesis of the background infections. one of the significant factors causing an increase of albino rats resistance to tularemia in mixed infection was activation of the immunomorphological reaction promoting accelerated development of specific immunit ... | 1978 | 415458 |
| an outbreak of tularemia in mink. | an outbreak of tularemia in farm raised mink is reported. twenty-six of approximately 5000 mink succumbed within a 10 day period. prodromal signs were minimal. necropsy revealed necrotic nodules scattered in the parenchyma of the lungs, liver, spleen, and mesenteric lymph nodes. francisella tularensis was isolated from spleens, livers and lungs. | 1978 | 618716 |
| tularemia in canada: francisella tularensis agglutinins in alberta ground squirrel sera. | 1978 | 638920 | |
| investigations of mammals in the surroundings of akhtopol (bulgaria) on the incidence of tularemia. | 1978 | 640529 | |
| involvement of hepatic metallothioneins in hypozincemia associated with bacterial infection. | hypozincemia was induced in rats by salmonella typhimurium and live vaccine strain francisella tularensis (lvs) infections. hepatic synthesis of zinc-binding proteins (zbp) was studied in order to elucidate the mechanisms involved in the redistribution of zinc from plasma to liver occurring during infectious illness. zbp, labeled in vivo with 65zn, were isolated and identified as metallothioneins based, in part, on their heat stability, dimorphism, and amino acid composition. cysteine was the ma ... | 1978 | 645856 |
| [the role of lemmings in natural tularemia foci of arctic regions]. | the presence of taimyr of independent natural tularemia foci of tundra type was revealed on the basis of isolation of tularemia causative agent from lemmings and the objects of external environment and detection of a specific antigen in the pellets of birds-myophages and mummified cadavers of animals. possible ways of circulation of the microbe in the lemming population are discussed. | 1978 | 665024 |
| [geographical difference in susceptibility to macrolide antibiotics among naturally occurring strains of francisella tularensis (author's transl)]. | 1978 | 671743 | |
| [selected chapters from clinical bacteriology. v. tularemia]. | 1978 | 674083 | |
| [sensitivity of the causative agent of tularemia to antibiotics]. | sensitivity of the tularemia causative agent of different geographical races to antibiotics such as streptomycin, tetracycline, gentamicin, rifampicin (20 strains), ampicillin, polymyxin m, erythromycin, oleandomycin (361 strains) and lincomycin (294 strains) was studied. high sensitivity of the tularemi a microbe to streptomycin, tetracycline, rifampicin (mic of 10 gamma/ml), gentamicin (mic of 1 gamma/ml) and resistance to 50 gamma of ampicillin and 1000 gamma/ml of polymyxin m were found. com ... | 1978 | 686695 |
| enigmatic resistance of sheep (ovis aries) to infection by virulent francisella tularensis. | tularemia in range sheep is an occasional cause of severe economic loss from mortality and unthriftiness as well as a hazard to persons in contact with the animals. epizootics are unpredictable and explosive, therefore, prophylaxis is more practical than therapy. live vaccine of proven value in man and in beavers was inoculated into mature ewes and elicited antibodies without harm to the sheep. however, challenge of immunity was not possible because virulent francisella tularensis in large doses ... | 1978 | 688073 |
| [present-day status of tularemia prevention in the ussr and further tasks]. | despite the presence of natural foci of infection at the territory of all the union republics (excluding the kirghiz ssr) and intensive epizootics among rodents, tularemia in the ussr is under full control from 1965. further differentiation of antitularemia measures, depending on local conditions of economy management and the presence of natural foci of infection is necessary. | 1978 | 746999 |
| [experimental substantiation of the possibility of aerosol immunization with a live tularemia vaccine]. | 1978 | 747027 | |
| stimulation of subpopulations of human lymphocytes by a vaccine strain of francisella tularensis. | when purified t lymphocytes from individuals vaccinated with a viable, attenuated strain of francisella tularensis were incubated in vitro in the presence of heat-killed bacteria or a membrane preparation of the vaccine strain, they were stimulated to form blast cells and to synthesize deoxyribonucleic acid. the blast cells had the characteristics of t cells, being devoid of surface immunoglobulin and able to form rosettes with sheep erythrocytes. the stimulation occurred only when monocytes wer ... | 1978 | 307538 |
| [effectiveness of the tularemia-antibody erythrocyte diagnostic agent for the detection of specific antigen and antibodies to it]. | the authors demonstrated the efficacy of utilization of tularemia antibody erythrocytic diagnostic agent. data are presented indicating a strict specificity and a high sensitivity of this diagnostic agent for detection of the vi-antigen both in the tularemia microbe cultures and in the suspensions of the organs of rodents which perished of tularemia, irrespective of the state of cadaver. there was revealed relationship between the sensitivity of the diagnostic agent and the virulence of the tula ... | 1978 | 78604 |
| activated lymphocytes trigger lymphoblast extravasation. | 1978 | 96942 | |
| tularemia in metropolitan new york. | 1978 | 280774 | |
| [exploration of natural foci of tularemia and plague in armenia using the serological examination of bird droppings and excrements of predatory mammals]. | forty strains of tularemia and 619 of plague microbes were isolated in 1974 in bacteriological examination of natural plague and tularemia foci from a great number of small mammals and their ectoparasites. at the same time in serological examination (in the antibody neutralization test) of bird pellets, 52 mummified cadavers, and 34 excretion samples of mammalian beasts of prey collected in armenia (its central and north-western part) in 1973 the antigen of tularemia microbe was revealed in 73, ... | 1978 | 149478 |
| [sensitivity to the differential dose of erythromycin and oleandomycin of various holarctic strains of tularemia microbe isolated in the kazakh ssr]. | the presence of strains of holarctic race of tuleremia microbe, both sensitive and resistant to the differential doses of erythromycine and oleandomycine was revealed at the territoryn of kazakh ssr. the existence of such strains does not permit to differentiate them into geographical races by the sensitivity to erythromycine and oleandomycine. | 1978 | 150182 |
| [geographical race typing of the causative agent of tularemia using antibiotics]. | reaction of the strains of the tularemia causative agent to erythromycin (100 gamma/ml) or oleandomycin (400 gamma/ml) is one of the taxonomic tests. the study of 82 strains of the holarctic race and 63 strains of the central asiatic race according to this test showed that the strains of the holarctic race were divided with respect to these macrolides into sensitive (biotype i) and resistant (biotype ii). the strains of the both races were isolated at the territory of the kazakh ssr. such a reac ... | 1978 | 151527 |
| [study of f. tularensis susceptibility to erythromycin in vitro (author's transl)]. | 1978 | 151594 | |
| a serologic survey of mule deer and elk in utah. | sera from mule deer (odocoileus hemionus) and elk (cervus canadensis) in central and northern utah were tested for the prevalence of antibodies to 11 diseases communicable to man or domestic livestock. antibodies to francisella tularensis (at 1:20) were found in 47 of 88 (53.4%) elk and 1 of 89 (1.1%) deer. a screening slide agglutination test for titers to brucella (at 1:20) showed two reactors in elk but none in deer sera. no positive antibody titers were obtained in tests for anaplasmosis, co ... | 1978 | 105153 |
| [accelerated diagnostic cultivation of pathogenic environmental microbes. ii. accelerated diagnostic cultivation of the causative agents of anthropozoonotic plague, glamders, melioidosis, brucellosis and tularemia]. | 1978 | 106632 | |
| changes in whole blood and serum components of grivet monkeys with experimental respiratory francisella tularensis infection. | grivet monkeys infected with virulent francisella tularensis strain schu s4 showed significant early changes in serum levels of trace metals, triglycerides and activities of alkaline phosphatase, lactate dehydrogenase and alpha-hydroxybutyrate dehydrogenase. free amino acid levels decreased slightly and there was a marked increase in the phenylalanine: tyrosine ratio. serum lysozyme activity and seromucoid levels also increased. kanamycin therapy produced remission of overt signs but the changes ... | 1978 | 106870 |
| differential effect of parenteral zinc on the course of various bacterial infections. | 1977 | 22081 | |
| the active e-rosette test: a sensitive in vitro correlate for human delayed-type hypersensitivity. | the "active" rosette test was adapted as an in vitro assay and correlated with human delayed cutaneous hypersensitivity (dch) to two microbial antigens. peripheral lymphocytes were purified from donors known to be responders or nonresponders to ppd-tuberculin or tularemia on the basis of prior dch reactions. skin test antigen, incubated with lymphocytes from antigen-sensitive donors, produced a significant increase (+2 s.d.) in the ability of the lymphocytes to form active rosette-forming cells ... | 1977 | 299750 |
| changes in whole blood and serum components during francisella tularensis and rabbit pox infections of rabbits. | rabbits infected with virulent francisella tularensis strain schu s4 or rabbit pox virus (utrecht strain) showed significant early changes in serum levels of trace metals, neutral fat and alkaline phosphatase activity. with f. tularensis infections a marked early leukopenia and a decrease in serum amino acids were also observed; the effect on amino acid levels was less pronounced in rabbit pox infections. in both diseases these changes preceded the appearance of acute phase globulins in the seru ... | 1977 | 204323 |
| endotoxin effects on the liver. | 1977 | 320416 | |
| cultivation and isolation of francisella tularensis on selective chocolate agar, as used routinely for the isolation of gonoccocci. | 1977 | 320819 | |
| determination of antibacterial antibodies in serum by immunoradiometric assays. | when used to determine immunopurified antibacterial globulins in saline-phosphate buffer, the detection sensitivities of direct competitive and indirect immunoradiometric assays were respectively 25 and 2 ng. normal human and rabbit sera interfered in both types of assay, markedly decreasing sensitivity and precision. various pre-treatments of sera and modifications of reaction conditions substantially decreased interference in the competitive assay without affecting the activity of added antibo ... | 1977 | 323486 |
| [change in phagocytic activity toward the agent of tularemia in highly sensitive animals with mixed infections]. | an increase of the ingestive and digestive capacity of neutrophils to the homologous causative agent and tularemia microbe was revealed by the opsonophagocytic test in microtus arvalis, albino mice and guinea pigs infected with sublethal yersinia pseudotuberculosis and salmonella typhimurium doses. in subsequent tularemia infection some of the animals displayed a reduction of the septicemia intensity, prolongation of the disease and elevation of the susceptibility threshold. period of manifestat ... | 1977 | 325967 |
| isolation of francisella tularensis from infected frozen human blood. | francisella tularensis was isolated from human blood that was frozen for 3 months before it was examined. before he became ill, the patient operated a "bush-hog" in an area thickly populated with rabbits. his illness was undiagnosed and untreated before his death. portions of blood and tissue homogenates from necropsy were injected intraperitoneally into mice and inoculated onto glucose-cysteine-blood agar plates. f. tularensis did not grow from the culture plates, but mice inoculated with the b ... | 1977 | 328528 |
| [agents of zoonoses and the environment of their habitats. iii. adaptive variability and ecotypes]. | 1977 | 405989 | |
| host resistance to the lvs strain of francisella tularensis in bcg vaccinated mice. | 1977 | 411926 | |
| [cytopathic effect of the tularemia microbe on a culture of peritoneal macrophages]. | morphological analysis of the process of interaction of tularemia microbe strains differing by virulence with macrophages demonstrated that all these strains produced a lethal effect on macrophages obtained from the animales sensitive to the infection. the macrophages obtained from the animals were but little sensitive to tularemia and were resistant to the action of the causative agent of this infection. the data obtained led to a supposition on the presence in the tularemia causative agent of ... | 1977 | 562567 |
| virulence factors of francisella tularensis. | the mechanism causing viable francisella tularensis to lose virulence in aerosols has been investigated. fully virulent organisms were found to be encapsulated and avirulent organisms from aged aerosols, decapsulated. capsules were also removed by suspension of f. tularensis in hypertonic sodium chloride. the resulting naked, but viable, organisms were predominantly avirulent for guinea-pigs challenged intraperitoneally. capsular material and cell walls were found to contain large amounts of lip ... | 1977 | 267668 |
| cat-bite tularemia. | 1977 | 578542 | |
| immunization against tularemia: analysis of the effectiveness of live francisella tularensis vaccine in prevention of laboratory-acquired tularemia. | a retrospective analysis was made of cases of laboratory-acquired infections with francisella tularensis among civilian employees at fort detrick, maryland. the incidence and clinical presentation of tularemia during the decade 1950-1959, when the phenol-killed foshay vaccine was used routinely for immunization of employees, were compared with similar data from the first decade (1960-1969) after the live tularemia vaccine had come into use. the incidence of typhoidal tularemia fell (from 5.70 to ... | 1977 | 833449 |
| [detection of the agent of tularemia in the mongolian people's republic]. | 1977 | 855520 | |
| modulation of delayed-type hypersensitivity and cellular immunity to microbial vaccines: effects of cyclophosphamide on the immune response to tularemia vaccine. | treatment of guinea pigs with cyclophosphamide before immunization with killed tularemia vaccine in freund incomplete adjuvant produced a prolongation and intensification of delayed-type hypersensitivity and in vitro lymphocyte transformation reactions to tularemia antigen. such reactions resemble those ordinarily associated with the administration of live tularemia vaccine, killed vaccine in freund complete adjuvant, or recovery from natural infection. the immunopotentiation lasted longer than ... | 1977 | 924675 |
| [isolation of bordetella bronchiseptica strains from wild animals captured in ankara, konya, urfa and viransehir'de]. | 1976 | 933893 | |
| [catalase activity in the agent of tularemia]. | the catalase activity was studied in the extracts of 27 strains of francisella tularensis belonging to three geographical races. the most active enzyme was possessed by nonarctic strains, and the least--by holarctic. japanese variant of the holarctic race was separated in an individual group since it possessed a higher catalase activity in comparison with the typical strains. the central asian race occupied an intermediate position by this sign and was placed between the japanese variant and the ... | 1976 | 941605 |
| pathogenesis and pathology of respiratory tularaemia in the rabbit. | the development of pathological lesions in the organs of rabbits was examined at intervals from 1 h to 4 days after aerosol infection with francisella tularensis. the earliest change, accumulation of polymorphonuclear leucocytes (pmn) in ulmonary alveolar ducts, occurred at 19 h. from the 2nd day multiple foci of necrosis and pmn infiltration were present in large airways and alveoli throughout the lungs and progressively increased in size. pulmonary arteritis was a prominent feature of the infe ... | 1976 | 952731 |
| [brucellosis, tularemia and borreliosis isolated from wild animals captured in ankara, konya, urfa and nevsehir provinces in turkey]. | 621 citellus, 41 mus musculus, 35 microtus, 442 meriones, 70 rattus rattus, 56 turtle, 89 hare, 1 hamster, 1 hedgehog and 1 sea snake, altogether 1379 wild animals were captured in ankara, konya, urfa and nevşehir. neither brucella or francisella tularansis could be isolated nor borrelia could be seen. 1/40-1/80 agglutination titers obtained in 3 out of 134 sera taken from citellus, in 3 out of 264 sera taken from guinea pigs which were inoculated with spleen, liver and kidney suspensions of wil ... | 1976 | 979704 |
| [mixed infection with tularemia and omsk hemorrhagic fever in experiments on aquatic field mice]. | the authors carried out an experimental study of some aspects of the pathogenesis of mixed tularemia and omsk hemorrhagic fever infection in arvicola terrestris l. the results obtained reflected the dynamics of development of the pathological process of the mixed infection, peculiarities of distribution of francisella tularensis and of the viral antigen in different organs, the character of pathomorphological changes in the organism at different periods after the administration of the causative ... | 1976 | 983583 |
| [role of gamasids in the epizootiology of tularemia]. | 10 strains of francisella tularensis were isolated from 4 species of gamasid mites, laelaps muris, l. multispinosus, hyperlaelaps amphibius and haemolaelaps glasgowi, in natural nidi of tularemia in the tumen district. under experimental conditions l. muris is often infected with tularemia agent on sick animals but preserves it at an indoor temperature not more than a week and does not transmit it transovarially. haemogamasus ambulans preserve the agent within the same period. l. muris and hirst ... | 1976 | 1023146 |
| [immunologic shifts in the body of albino rats under the effect of chloroprene]. | 1976 | 1025975 | |
| evolution and taxonomy in the genus brucella: concepts on the origins of the contemporary species. | the flow of thought on evolution of the organisms in the genus brucella was traced through the literature. the finding of brucella suis type 2 in hares provided impetus for much speculation on the changeability of species characteristics. recent reports, largely by soviet investigators, focus on the subjects of the sweep of evolution in this genus through eons of the geologic time scale and also on the possible parentages of the recently discovered species. these papers were translated and perti ... | 1976 | 816230 |
| an indirect immunoradiometric assay of microbes. | 1976 | 819619 | |
| an indirect radiolabelled antibody staining technique for the rapid detection and identification of bacteria. | 1976 | 821910 | |
| [preservation of the causative agent of tularemia in the external environment in eastern taimyr]. | strains of the causative agent of tularemia were for the first time isolated by the authors from the objects of the external environment in the tundra zone of eastern taimir; this indicates a possibility of preservation of the microbe under conditions of the extreme north. | 1976 | 1266471 |
| [stabilization of the immunogenic properties of vaccinal strains of bacteria]. | 1976 | 790870 | |
| [sensitivity of various races of the tularemia microbe to erythromycin, oleandomycin and polymyxin]. | sensitivity of 66 strains of the tularemia microbe to erythromycin, oleandomycin and polymyxin was studied. it was shown that all the strains were resistant to polymyxin. the strains of the non-artic and central asiatic races and 64 per cent of the strains of the holarctic race were resistant to erythromycin and oleandomycin. | 1976 | 179462 |
| the effect of bacterial infections on ketone concentrations in rat liver and blood and on free fatty acid concentrations in rat blood. | the concentrations of cytoplasmic lactate and pyruvate and the nad+/nadh ratio and the concentrations of mitochondrial acetoacetate, beta-hydroxybutyrate, and the nad+/nadh ratio were determined in normal, fed, and fasted rats, and in rats infected with streptococcus pneumoniae, francisella tularensis, and salmonella typhimurium. the various infections were found to have little or no effect on the cytoplasmic parameters. in normal rats, fasting caused a marked increase in blood and hepatic keton ... | 1976 | 181658 |