Publications

use of sodium dodecyl sulfate-polymyxin b-sucrose medium for isolation of vibrio vulnificus from shellfish.	the differential and selective sodium dodecyl sulfate-polymyxin b-sucrose medium (sps) of kitaura et al. (t. kitaura, s. doke, i. azuma, m. imaida, k. miyano, k. harada, and e. yabuuchii, fems microbiol. lett. 17:205-209, 1983), which highlights alkylsulfatase activity, was evaluated for its potential use in the direct isolation and enumeration of vibrio vulnificus from shellfish. v. vulnificus was detected by this method in six of nine shellfish samples collected from diverse geographic locales ...	1987	3662506
rat lung lectin synthesis, degradation and activation. developmental regulation and modulation by dexamethasone.	soluble lectins are widely distributed cell-agglutinating proteins. their activity is developmentally regulated in several tissues, including the lung, but virtually nothing is known about the mechanisms of the developmental regulation or the turnover of these proteins. we studied mechanisms that might be responsible for the developmentally regulated changes in the activity of a lectin (beta-galactoside-binding protein) found in the lung, and determined if its activity or turnover could be modul ...	1987	3663186
extended and globular protein domains in cartilage proteoglycans.	electron microscopy after rotary shadowing and negative staining of the large chondroitin sulphate proteoglycan from rat chondrosarcoma, bovine nasal cartilage and pig laryngeal cartilage demonstrated a unique multidomain structure for the protein core. a main characteristic is a pair of globular domains (diameter 6-8 nm), one of which forms the n-terminal hyaluronate-binding region. they are connected by a 25 nm-long rod-like domain of limited flexibility. this segment is continued by a 280 nm- ...	1987	3663190
studies on membrane proteins involved in ribosome binding on the rough endoplasmic reticulum. ribophorins have no ribosome-binding activity.	a membrane protein fraction showing affinity for ribosomes was isolated from rat liver microsomes (microsomal fractions) in association with ribosomes by treatment of the microsomes with emulgen 913 and then solubilized from the ribosomes with sodium deoxycholate. this protein fraction was separated into two fractions, glycoproteins, including ribophorins i and ii, and non-glycoproteins, virtually free from ribophorins i and ii, on concanavalin a-sepharose columns. the two fractions were each re ...	1987	3663192
na+ modulates the k+ permeability and the membrane potential of alkalophilic bacillus.	in the absence of na+ in the medium, the membrane potential of obligately alkalophilic bacillus cells was found to be decreased by the addition of k+ to the medium, whereas k+ addition in the presence of na+ had no effect. rb+ showed essentially the same effect as k+. the decreased membrane potential was quickly restored by lowering the k+ concentration in the medium or by adding na+ or li+ to the medium. thus, in the absence of na+, the membrane potential of alkalophilic bacillus seems to be af ...	1987	3663674
the effects of uv-b irradiation on the corneal endothelium.	rabbit eyes, in vivo and in vitro, were exposed to uv-b irradiation at 300 nm, from a mercury arc lamp with an 11 nm bandpass filter. radiant exposure ranged from 0.1 j/cm2 to 0.5 j/cm2. in vivo, swelling of the cornea resulted over a 12 to 40 hr period, the extent and duration being directly related to exposure. recovery of normal thickness was complete within four days. corneas removed at 18 hr after exposure recovered normal thickness during a five hour perfusion period, except for those most ...	1987	3665557
gentamicin- and methicillin-resistant staphylococcus aureus: in vitro susceptibility to antimicrobial drugs.	thirteen nosocomially significant, gentamicin- and methicillin-resistant (grmr) staphylococcus aureus isolates, all of phage group iii/m (lysotype 42e/47/53/54/75/77/83a/84/85/94/96), were uniformly resistant against augmentin, erythromycin, fosfomycin, gentamicin, methicillin, oxacillin, penicillin g, tetracycline, and tobramycin, but differed in susceptibility to cefamandole, ciprofloxacin, clindamycin, imipenem, josamycin, the synthetic chinolone ro 23-6240, and ofloxacin. all isolates were s ...	1987	3665635
properties of in vitro nonenzymatically glycated plasma fibrinogens.	nonenzymatic glycation of fibrinogen is species independent and depends only on the glucose concentration in the incubation mixture under selected in vitro conditions. an increased fibrin monomer aggregation in the presence of ca2+ ions and a decreased proteolytic susceptibility of nonenzymatically glycated fibrinogens may favour the development of thrombophilic states. blocking of lysine residues as well as restricted conformational changes induced by glucose attachment may be responsible for t ...	1987	3666059
binding of anti idiotypic antibodies against anti fsh to fsh receptors.		1987	3666824
strategy for the analysis of steryl esters from plant and animal tissues.	methods are described for the analysis of intact steryl esters present in complex mixtures isolated from plant or animal tissues. a preliminary examination by analytical thin-layer chromatography (tlc) and capillary column gas chromatography-mass spectrometry (gc-ms) under electron impact (ei) ionisation reveals the complexity of the mixture and the nature of the steryl moieties. preparative tlc is then utilised to separate the steryl esters into two broad groups, containing fatty acyl moieties ...	1987	3667746
liquid chromatographic analysis of alizapride and metoclopramide in human plasma and urine using solid-phase extraction.	a universal rapid, sensitive and selective high-performance liquid chromatographic method with uv detection at 230 nm has been developed for the determination of benzamide drugs in human plasma and urine. sample pretreatment is carried out using solid-phase extraction columns, resulting in very high extraction recoveries of the compounds investigated (alizapride, metoclopramide, alpiropride, amisulpride). the detector response is linear from 25 to 10,000 ng/ml, and the detection limit is 3 ng/ml ...	1987	3667781
acinetobacter calcoaceticus infection following a dog bite.	a frequent complication of dog bite wounds is bacterial infection. the choice of antibiotics is based upon the most likely organisms. failure to achieve wound healing suggests that an uncommon organism(s) is present and should lead the clinician to culture the wound. a case of acinetobacter calcoaceticus infection following a dog bite is described.	1987	3668199
[clinical studies on cefuzonam in the field of obstetrics and gynecology].	in gynecological infections, especially intrapelvic infections, it is sometimes difficult to identify causal microorganisms. in those cases, it becomes a hard task to select most effective antibiotics, hence the use of wide-spectrum antibiotics becomes necessary. we recently had opportunities to clinically use cefuzonam (czon, l-105) which has a wide range of spectrum against various bacteria including staphylococcus aureus, escherichia coli, gram-positive and gram-negative anaerobes, etc. the f ...	1987	3669287
[roentgeno-morphological characteristics of post-traumatic deformities in children].		1987	3670811
surgical anatomy of the mimic muscle system and the facial nerve: importance for reconstructive and aesthetic surgery.	mimic muscles are arranged in four layers regarding their origins, and these four layers should be considered when muscle tissue is added or lifted. all mimic muscles are built up by parallel fibers. mean values of length, width, and thickness of the three lip elevators have been determined. these data might be of importance when dealing with this muscle system, which appears rather different from all other muscles in the human. the individual muscles receive their innervating facial nerve branc ...	1987	3671560
[effect of therapeutic administration of purine derivatives on the life span of irradiated animals].	purine derivatives, meradine and ethimizole, are shown to exert a therapeutic effect with respect to survival of rats exposed to 4 gy radiation. distinctions in the death rate between the exposed rats and rats treated with meradine and ethimizole are manifested 1 month following irradiation, i. e. at the time of clinical recovery of the exposed body. the preparations used at other te terms are uneffective. it is suggested that purine derivatives increase the regeneration and compensation of radi ...	1987	3671682
measurement of renal pelvis pressures during endourologic procedures.	twenty-five kidneys underwent nephrostomy puncture with placement of a pigtail catheter into an upper pole calyx for manometric recording during nephroscopy without a working sheath and with an amplatz sheath with and without a rutner adapter. intrarenal pressures remained below 16 cm of water (h2o) at all times with the amplatz sheath with or without a rutner adapter, whereas without a sheath the pressures ranged from 15 to 31 cm h2o (i.e., pressures associated with significant pyelovenous and ...	1987	3672683
further observations on the stability of cholera vaccine at different temperatures.	the stability of cholera vaccine samples held at 4-8 and 20-25 degrees c for 2 1/2 years was studied with regard to the number of organisms, total nitrogen content and relative antigenicity. after this length of time, the percentage loss in the number of organisms averaged 10.7 at 4-8 degrees c and 22.7 at 20-25 degrees c. the maximum loss in number of organisms took place during the first six months and in the next two years there was very little loss in the number of organisms. the total nitro ...	1987	3673205
monensin toxicosis in swine: potentiation by tiamulin administration and ameliorative effect of treatment with selenium and/or vitamin e.	modulation of acute monensin toxicosis in swine was evaluated in 2 studies. in study 1, 56 weanling male pigs were allotted to 14 groups of 4 each. pigs in 7 groups were given tiamulin in the drinking water (to supply 7.7 mg/kg of body weight/day) for 3 days before and for 2 days after monensin administration. monensin was given as a single oral dose (at 0, 7.5, 15, 25, 50, 75, or 100 mg/kg) to pigs in groups with or without tiamulin exposure. prominent acute clinical signs of monensin toxicosis ...	1987	3674564
new selective and differential medium for vibrio cholerae and vibrio vulnificus.	thiosulfate-citrate-bile salts-sucrose agar has been routinely used for the isolation of pathogenic vibrios, although its selectivity for vibrio cholerae and vibrio vulnificus is inadequate. therefore, a new plating medium, cellobiose-polymyxin b-colistin agar, was developed for the isolation of these two species. cellobiose-polymyxin b-colistin agar demonstrated a significant advantage over other media designed for the isolation or differentiation of vibrios: of both the 136 strains representin ...	1987	3674873
erythrocyte and granulocyte interactions with endothelialized polymer surfaces.		1987	3675980
influence of exercise on ascorbic acid status in man.	1. the response of circulating leucocytes with regard to changes in number, proportion of granulocytes and lymphocytes, as well as changes in the ascorbic acid (aa) concentration of plasma and isolated lymphocytes, were studied in nine men who ran a 21 km race. a marked leucocytosis was noted 5 min after the race, the predominant increase being in granulocytes (p less than 0.001) with smaller relative increases in circulating lymphocytes (p less than 0.01) and platelets (p less than 0.001). numb ...	1987	3677557
influence of exercise on ascorbic acid status in man.	1. the response of circulating leucocytes with regard to changes in number, proportion of granulocytes and lymphocytes, as well as changes in the ascorbic acid (aa) concentration of plasma and isolated lymphocytes, were studied in nine men who ran a 21 km race. a marked leucocytosis was noted 5 min after the race, the predominant increase being in granulocytes (p less than 0.001) with smaller relative increases in circulating lymphocytes (p less than 0.01) and platelets (p less than 0.001). numb ...	1987	3677557
increased uptake of 5-fu in experimental liver tumours by simultaneous infusion of norepinephrine.	the effect of the simultaneous administration of norepinephrine and 5-fluorouracil (5-fu) on the uptake of radiolabelled 5-fu by liver tumours was studied in rats. three different concentrations of 5-fu were used (15, 1.5 and 0.15 microgram/g body weight). the drugs were infused over a 30 min period via the hepatic artery, following cannulation of the gastroduodenal artery. the radioactivity in liver tumour, normal liver, lungs and intestines was estimated by liquid scintillation counting. at al ...	1987	3678326
aging and the auditory brainstem response in mice with severe or minimal presbycusis.	threshold, latency, and amplitude of the auditory brainstem response (abr) were obtained with filtered noise pips in young and aging c57bl/6j mice (to 16-months), which undergo severe progressive age-related sensorineural hearing loss (presbycusis) and cba/j mice (to 19-months), which show only mild loss late in life. aging per se (cba mice) is not associated with significant changes in abr parameters. presbycusis, in aging c57 mice, is associated with increased thresholds; there is a trend towa ...	1987	3680066
synthesis and cardiac electrophysiological activity of 2- and 3-[(substituted phenyl)alkyl]quinuclidines. structure-activity relationships.	the syntheses and cardiac electrophysiological effects of 21 2- and 3-substituted quinuclidines and some quaternary ammonium derivatives are described. the 2-substituted quinuclidines 2-8 were prepared by alkylation of 2-methylene-3-quinuclidinone. the wittig reaction with 3-quinuclidinone afforded the 3-substituted derivative 9, which was subsequently converted to 10 and 11. the electrophysiological profiles of the compounds were determined in canine cardiac purkinje fibers and ventricular musc ...	1987	3681896
[various hemodynamic mechanisms of the hypertensive reaction in immobilization-induced stress in rabbits and rats].	the radioactive microsphere technique was used to measure the cardiac output, regional blood flows and resistances in conscious rabbits and rats before and after 30-minute immobilization. immobilization evoked blood pressure rise in both species. cardiac output was reduced and total peripheral resistance increased in rabbits. reverse changes of these parameters were observed in rats. blood flow was reduced in the liver and the right ventricle in rabbits, and in the testes in rats. in immobilized ...	1987	3682581
quantitative evaluation of colonizing ability of vibrio cholerae o1.	a new method to evaluate the adhesive ability of vibrio cholerae o1 was proposed. broth cultured v. cholerae o1 and a piece of formalin-fixed rabbit intestinal wall were incubated together in krt buffer and the number of adhered organisms was counted under a scanning electron microscope. this method was much less laborious than other methods that have been used so far, and most significantly, constant results were obtained in repeated experiments. the adhesive properties of toxigenic v. cholerae ...	1987	3683218
oral immunization in adult mice to live and heat-killed vibrio cholerae.	effects of systemic and intestinal local immune responses in mice fed ad libitum and forcedly with live or heat-killed vibrio cholerae on the elimination of vibrios from the intestine were investigated. in mice fed with live vibrios, ad libitum feeding could induce potential delayed-type hypersensitivity and rapid production of vibriocidal antibody in the serum whereas forcedly feeding suppressed the delayed-type hypersensitivity and retarded the antibody production. in contrast, when killed mic ...	1987	3683219
the clinico-pathologic features of hepatitis b virus-associated glomerulonephritis.	the frequency of hepatitis b surface antigen (hbsag) was studied in the sera of 311 patients with various forms of primary glomerulonephritis and 43 patients with lupus nephritis. hbs antigenaemia was detected in 69 of the 311 patients (22 per cent) with primary glomerulonephritis and this prevalence of hbsag carrier was significantly higher than that in the general population (p less than 0.001). these patients had no clinical or biochemical findings to suggest acute or chronic liver disease. a ...	1987	3685245
ultraviolet inactivation and photoreactivation of the cholera phage 'kappa'.	the lysogenic cholera phage, 'kappa' is some ten to twenty folds more resistant to uv (254 nm) than are most of the t. phages of e. coli, or the cholera phage pl 163/10, or the host v. cholerae strain h218 smr, the 37% (d37) and 10% (d10) survival doses being 255.8 j/m2 and 633.6 j/m2 respectively. the uv-irradiated 'kappa' phages could be photoreactivated in the host v. cholerae strain h218 smr to a maximum extent of 40%. the removal of the number of lethal hits per phage by the survival-enhanc ...	1987	3685253
altitude, radiation, and mortality from cancer and heart disease.	the variation in background radiation levels is an important source of information for estimating human risks associated with low-level exposure to ionizing radiation. several studies conducted in the united states, correlating mortality rates for cancer with estimated background radiation levels, found an unexpected inverse relationship. such results have been interpreted as suggesting that low levels of ionizing radiation may actually confer some benefit. an environmental factor strongly corre ...	1987	3685264
prevalence of biotypes, serotypes & phage-types of vibrio cholerae 0-1 in india (1975-1985).		1987	3583349
aeromonas veronii, a new ornithine decarboxylase-positive species that may cause diarrhea.	in 1983, the vernacular name enteric group 77 was coined for a group of strains that had been referred to our laboratory as "possible vibrio cholerae except for gas production." by dna-dna hybridization (hydroxyapatite, 32p), 8 of 10 strains of enteric group 77 were very highly related to the labeled strain 1169-83 (74 to 100% at 60 degrees c and 75 to 100% at 75 degrees c; percent divergence, 0.0 to 2.5). type strains of six other aeromonas species were 45 to 66% related (60 degrees c) to strai ...	1987	3584425
phage-induced change of toxigenesis in vibrio cholerae.	a temperate phage coding for constitutive hypertoxigenicity has been constructed in vibrio cholerae strain 569b and used to lysogenise the low-toxin-producing strain mak 757; 18% of lysogens showed 10-100-fold increase in toxin production. this property was also transmitted at low frequency to second generation lysogens. thus temperate phage can increase toxin production in a low-toxin-producing strain.	1987	3585965
effect of water coagulation by seeds of moringa oleifera on bacterial concentrations.	the effects of a sudanese water purification method traditionally used in sudan to treat turbid waters were studied with respect to turbidity reduction and removal of faecal indicator bacteria as well as selected enteric bacterial pathogens. water treatment was performed at 30 degrees c with moringa oleifera seed material as a coagulant, and the technique employed corresponded closely to that used to clarify turbid water in sudanese villages. a turbidity reduction of 80.0-99.5% paralleled by a p ...	1987	3586089
an enzyme-linked immunosorbent assay to detect serum igg to pasteurella multocida in naturally and experimentally infected rabbits.	an enzyme-linked immunosorbent assay (elisa) was evaluated for efficacy in detecting serum igg against pasteurella multocida in both naturally and experimentally infected rabbits. blood samples and nasal cultures were taken concurrently from 58 rabbits from four conventional rabbitries. nine rabbits from a pasteurella-free colony served as negative controls. fifty-six rabbits were elisa positive. of these, 46 were p. multocida culture positive, 10 were culture negative. two rabbits were elisa ne ...	1987	3586606
an enzyme-linked immunosorbent assay to detect serum igg to pasteurella multocida in naturally and experimentally infected rabbits.	an enzyme-linked immunosorbent assay (elisa) was evaluated for efficacy in detecting serum igg against pasteurella multocida in both naturally and experimentally infected rabbits. blood samples and nasal cultures were taken concurrently from 58 rabbits from four conventional rabbitries. nine rabbits from a pasteurella-free colony served as negative controls. fifty-six rabbits were elisa positive. of these, 46 were p. multocida culture positive, 10 were culture negative. two rabbits were elisa ne ...	1987	3586606
[a severe form of external otitis: necrosing diabetic otitis].	otitis externa are of usual observation in inter-tropical regions. pseudomonas aeruginosa is responsible generally. but, when immunodeficiency is associated or on diabetic diathesis, such an otitis externa can be extremely dangerous: extensive osteitis of the base of the skull, paralysis of the last pairs of cervical nerves rapidly creeping, built a clinical identity called malignant external otitis, leading to death in 50% of the cases.	1987	3586974
[mitochondrial calcium sequestration in myocardial cells in experimental acute organic phosphate ester (dimethoate) poisoning].		1987	3587248
the blocking of human antibody-dependent, eosinophil-mediated killing of schistosoma mansoni schistosomula by monoclonal antibodies which cross-react with a polysaccharide-containing egg antigen.	three igm monoclonal antibodies, m22g11p, m7b7 and m22p3g, which reacted with the surface of schistosoma mansoni schistosomula in an indirect fluorescent antibody assay, were found to recognize a polysaccharide-containing egg antigen previously designated k3. the monoclonal antibodies and a monospecific rabbit anti-k3 serum also recognized a cross-reacting antigen in a crude cercarial antigen preparation. in an eosinophil-mediated schistosomulum killing assay, all three monoclonal antibodies sig ...	1987	3588013
testicular defect: the primary abnormality in gonadal dysfunction of uremia.	gonadal dysfunction is a common problem in end-stage renal disease. we decided to test the ability of the male gonads to respond to exogenous stimuli. the patients receiving chronic hemodialysis showed abnormally low levels of total testosterone and free testosterone in the presence of normal testosterone-binding globulin. furthermore, the exogenous administration of human chorionic gonadotropin failed to elicit a normal response from the male gonads of hemodialyzed patients. although basal seru ...	1987	3589761
theophylline disposition in tetraplegic man.	we studied the time-course of serum theophylline concentration after a 30-minute intravenous infusion of aminophylline (6 mg/kg) in 18 traumatic tetraplegic (nine smoking, nine nonsmoking) and in six control (nonsmoking) subjects. all study subjects were healthy men with normal renal function. pharmacokinetic parameters were calculated from a linear regression analysis of the terminal log-linear portion of the log serum theophylline concentration-time curves. the terminal elimination kinetics of ...	1987	3589764
cholera toxin transcriptional activator toxr is a transmembrane dna binding protein.	the toxr gene encodes a transcriptional activator controlling cholera toxin, pilus, and outer-membrane protein expression in v. cholerae. nucleotide sequence and mutational analysis has identified the toxr gene product as a 32,527 dalton protein. hydropathicity analysis of the derived amino acid sequence of toxr predicts a transmembrane structure. the properties of hybrid proteins composed of n-terminal fragments of toxr fused to the periplasmic enzyme alkaline phosphatase provide additional evi ...	1987	3802195
non-01 vibrio cholerae infections in cancun, mexico.	to determine the role of vibrio cholerae as a cause of diarrheal illness in cancun, mexico, an investigation was conducted in july and august 1983. although toxigenic v. cholerae 01 were not found, non-01 v. cholerae were isolated from 22 (16%) of 134 stools from persons with diarrheal illness and none of 22 stools from well persons; 58 (92%) of 63 sewage samples; 12 (86%) of 14 untreated well water samples; a home storage tank for treated water; and 5 (21%) of 24 samples of raw seafood. none of ...	1987	3826498
nerve fibres and their terminals of the dura mater encephali of the rat.	the dura mater encephali of the rat is richly supplied by myelinated (a-axons) and unmyelinated (c-axons) nerve fibres. for the supratentorial part the main nerve supply stems from all three branches of the trigeminal nerve. finally, 250 myelinated and 800 unmyelinated nerve fibres innervate one side of the supratentorial part. the vascular bed of the dura mater exhibits long postcapillary venules up to 200 micron in length with segments of endothelial fenestration. lymphatic vessels occur withi ...	1987	3826655
a role for taste aversion learning in fla-57 induced reductions of voluntary alcohol intake.	it has been proposed by amit, brown and colleagues that the reduction in voluntary alcohol intake observed after the administration of fla-57 in rats can be attributed to decreased ne levels produced by fla-57. our studies investigated whether a conditioned taste aversion could better explain this phenomenon. in the key study, two groups of rats were injected with fla-57 or ringers before drinking alcohol for five days, while a third group was injected with fla-57 before exposure to intragastric ...	1987	3828060
clinical and microbiological investigation of women with acute salpingitis and their consorts.		1987	3828260
determinants of the immunogenicity of live virulent and mutant vibrio cholerae o1 in rabbit intestine.	determinants of the capacity of live vibrio cholerae o1 isolates to evoke specific immune responses in intestinal mucosa were studied in rabbits, using mucosal immunoglobulin a (iga) antitoxin as the measured immune response. antitoxin responses were evoked mostly by the primary inoculation and were dose dependent; secondary-type responses were modest and occurred only when the booster inoculum was large, i.e., 10(10) cfu. the efficiency of mucosal immunization correlated closely with the mucosa ...	1987	3804447
[effect of neuraminidase and x-rays (2 gy and 8 gy) on microvilli and membrane invaginations of ehrlich ascites tumor cells in monolayer culture].	a monolayer culture (eagle basal medium plus 10% of fetal calf serum) of ehrlich ascites tumor cells was exposed to x-radiation with 2 gy and 8 gy and treated with vibrio cholerae neuraminidase alone or combined with sublethal x-ray irradiation (2 gy). pictures of the ehrlich ascites tumor cells taken with the electron microscope were investigated in order to find out any cell surface modifications due to membrane invaginations and microvilli. the results showed that the rate of microvilli as we ...	1987	3810476
nonproductive, cell-associated virus exists before the appearance of antiviral antibodies in experimental measles encephalitis.	the ability of measles virus to induce a cell-associated state of infection in the central nervous system (cns) plays an important role in the pathogenesis of subacute sclerosing panencephalitis (sspe), a fatal disease of children and young adults. the mechanism by which such an infection state is established is unknown, but several hypotheses have been proposed. one of these suggests that antiviral antibodies induce the nonproductive infection state by a process termed antigenic modulation. res ...	1987	3811233
comparison of the pharmacological properties of pituitary and biosynthetic human growth hormone. demonstration of antinatriuretic/antidiuretic and barbital sleep effects of human growth hormone in rats.	biosynthetic human growth hormone was compared with pituitary human growth hormone and pituitary 22 k in the weight gain and the tibia test. the three preparations were found to be equipotent. furthermore, the growth hormones were compared in various pharmacological test systems. all three preparations were found to have a marked antidiuretic and antinatriuretic effect in the rat and to cause a significant shortening of the hexobarbital sleeping time in mice. biosynthetic and pituitary preparati ...	1987	3811769
hyperexcitability of cutaneous afferents during the supernormal period. relevance to paraesthesiae.	the excitability of cutaneous afferents in the median nerve of 20 normal human subjects was investigated using a supramaximal conditioning stimulus and a submaximal test stimulus that produced an afferent volley of 20 to 40% of maximum. the intensity of the test stimuli was 1.1 to 1.25 times threshold for the first recruited axons (defined as a compound action potential of approximately 0.5 microv). the amplitude of the test volley did not reach the control amplitude until conditioning-test inte ...	1987	3651792
in vitro production of cholera toxin-like activity by plesiomonas shigelloides.	although plesiomonas shigelloides is considered to cause diarrhea in humans, the mechanisms by which it might do so are not known. enteric pathogens such as vibrio cholerae and some strains of escherichia coli produce enterotoxins that activate adenylate cyclase, increase production of cyclic amp, and thereby cause elongation of chinese hamster ovary (cho) cells in tissue culture. we grew 28 strains of p. shigelloides and the type strain in an iron-depleted medium, and sterile filtrates were exa ...	1987	3655401
chest pain, shock, and pneumomediastinum in a previously healthy 56-year-old man.	it is apparent from this discussion that it may be exceedingly difficult to make the diagnosis of boerhaave's syndrome. the failure to correctly diagnose this patient was due, in part, to the absence of vomiting in the history. nevertheless, the presence of pneumomediastinum on the initial chest roentgenogram was a significant finding that was missed and would have suggested this diagnosis. this patient is an example of an "atypical" presentation and demonstrates that vomiting need not be a part ...	1987	3813174
small non-cleaved follicular center cell lymphoma in turkey. burkitt's and non-burkitt's types. a retrospective clinicopathologic analysis of 53 cases in the pediatric age group.	fifty-three patients in the pediatric age group diagnosed as having small non-cleaved follicular center cell (fcc) lymphoma (40 burkitt's and 13 non-burkitt's type) have been re-evaluated. although the histopathologic distinction between the two subgroups is fairly easy to determine there is a considerable degree of clinical overlap in regard to age, sex, anatomic presentation of the disease, the incidence of bone marrow and central nervous system involvement, and the survival. the most importan ...	1987	3815272
small non-cleaved follicular center cell lymphoma in turkey. burkitt's and non-burkitt's types. a retrospective clinicopathologic analysis of 53 cases in the pediatric age group.	fifty-three patients in the pediatric age group diagnosed as having small non-cleaved follicular center cell (fcc) lymphoma (40 burkitt's and 13 non-burkitt's type) have been re-evaluated. although the histopathologic distinction between the two subgroups is fairly easy to determine there is a considerable degree of clinical overlap in regard to age, sex, anatomic presentation of the disease, the incidence of bone marrow and central nervous system involvement, and the survival. the most importan ...	1987	3815272
effect of restricted caloric intake on azoxymethane-induced colon tumor incidence in male f344 rats.	the effect of 30% caloric restriction on azoxymethane (aom)-induced colon carcinogenesis was investigated in male f344 rats. starting at 5 weeks of age, groups of animals were fed ad libitum a high-fat (23.5%) semipurified diet. at 7 weeks of age, all animals except the vehicle-treated groups were s.c. injected with aom (15 mg/kg body wt, once weekly for 2 weeks). four days after the second aom injection, groups of animals were continued on high-fat diet and fed ad libitum (ad libitum group) whe ...	1987	3815332
carcinogenicity of mutagens: predictive capability of the salmonella mutagenesis assay for rodent carcinogenicity.	a total of 224 chemicals that have been tested in long-term studies for carcinogenicity in rats and mice by the national cancer institute and the national toxicology program were tested for mutagenicity in salmonella typhimurium. correlations between mutagenicity and carcinogenicity were examined. the influences of chemical structure, rodent species and organ responses, and bacterial strain responses on the carcinogenesis/mutagenesis correlations were also examined. not all carcinogens induced t ...	1987	3815340
paroxysmal hypertension due to sinoaortic baroreceptor denervation in humans.	a 41-year-old man with a remote history of neck and mediastinal radiation was seen with severe paroxysms of hypertension, headache, and cutaneous flushing after bilateral carotid bypass surgery. investigation revealed marked parallel fluctuations in blood pressure and heart rate and elevation of plasma norepinephrine to 1164 pg/ml during a paroxysm. we systematically evaluated his arterial and cardiopulmonary baroreceptor reflex function by assessing changes in heart rate, arterial pressure, and ...	1987	3818023
fibronectin gene expression in polymorphonuclear leukocytes. accumulation of mrna in inflammatory cells.	using a fibronectin cdna probe, we have studied the accumulation of fibronectin mrna in polymorphonuclear leukocytes (pmn) in response to inflammation. nonactivated pmn from human peripheral blood were used as a source of noninflammatory cells and pmn from inflamed knee joints of patients with chronic inflammatory joint disorders (rheumatoid and psoriatic arthritis) were used as a source of inflammatory cells. by dot blot and northern hybridization analysis, we have found the presence of fibrone ...	1987	3818588
time course of the reaction of glial fibers in the somatosensory thalamus after lesions in the dorsal column nuclei.	these experiments were designed to examine the relationship of glial hypertrophy to the time course of reactive synaptogenesis in the ventral posterolateral nucleus of the rat thalamus after lesions in the dorsal column nuclei. because synaptogenesis is delayed for 30 days following lesions of the dorsal column nuclei, the initial hypertrophy of the glial processes in response to degeneration can be separated temporally from synaptogenesis. glial hypertrophy was determined by measuring the relat ...	1987	3819027
postnatal development of growth hormone and prolactin cells in male and female rat pituitary. an immunocytochemical light and electron microscopic study.	localization and ultrastructural maturation of prolactin (prl) and growth hormone (gh) cells were studied in pituitaries from neonatal, immature (4-6 weeks old), and adult rats (2-3 months old) by light and electron microscopic immunocytochemistry. the distribution pattern of these cells did not change with age. both cell types were concentrated laterodorsally, with prl cells adjacent to the intermediate lobe and gh cells nearer the center of the pars distalis. labeling density of the immunogold ...	1987	3819376
nonlipopolysaccharide protective antigens shared by classical and el tor biotypes of vibrio cholerae.	the prophylactic significance of the nonlipopolysaccharide (non-lps) antigens of vibrio cholerae was investigated further with use of the infant mouse cholera model. of 16 strains examined to date, 12-including eight recent field isolates of both biotypes and both common serotypes-express common non-lps protective antigens. the exceptional strains are four old isolates of el tor biotype, the outer membrane proteins of which are not atypical when analyzed by immunoblotting. the protective activit ...	1987	3819476
preparation and immunogenicity of a bivalent cell-surface protein-polysaccharide conjugate of vibrio cholerae.	alkali-treated lipopolysaccharides (lps) from ogawa and inaba serotypes of vibrio cholerae were chemically coupled to cell-surface proteins of v. cholerae. the reaction product was eluted in the void volume when fractionated on a column of sephacryl s-300. the material did not enter the gel when subjected to polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate (sds-page). the bivalent protein-polysaccharide conjugate was nonpyrogenic, as determined by the limulus lysate ...	1987	3820275
influence of bordetella avium infection on association of escherichia coli with turkey trachea.	four-week-old bordetella avium-infected and b avium-free turkeys were inoculated intratracheally with a suspension of fimbriated or nonfimbriated escherichia coli. numbers of e coli associated with tracheal sections were determined at postinoculation hour (pih) 1 or 6. significantly (p less than 0.05) greater numbers of e coli were isolated from the tracheas of b avium-infected turkeys compared with numbers in b avium-free turkeys. in b avium-free turkeys, tracheal associated e coli were 90% les ...	1987	2893567
[fronto-orbito-nasal dislocations. initial total reconstruction. tactics. advantages. conditions].		1987	269473
[single-stage restoration of dental defects with composite material using provisional plastic crown forms].		1987	299307
'fairfield' chosen for national centre.		1987	260662
[testicular tumors. analysis of observations from the urological departments of slovakia during 1965-1974].		1987	204093
presidential politics and health care issues.		1987	1453420
food allergy--fact or fiction: a review.	food sensitivity is a common condition presenting with various clinical syndromes including migraine, urticaria, gluten enteropathy, crohn's disease and irritable bowel syndrome. it is a heterogeneous condition affecting different organ systems and is also aetiologically diverse with subgroups due to allergy, pharmacological reactions, enzyme deficiencies and psychological causes. clinical acceptance of food sensitivity has been delayed by the use of dubious diagnostic techniques by a minority o ...	1987	1433127
autoradiographic and biochemical studies of steroid hormone-concentrating cells in the brain of rana pipiens.		1987	304754
[observations at the 1979/80 year change: what all has happened within our field in the 1970s?].		1987	260477
[don't want to cooperate in medical research project].		1987	260473
nursing, a helping relationship?		1987	254116
[clinical significance of insulin determination].		1987	203830
[interview with the norwegian nursing and research scholar kari martinsen: nursing research: nurses should stick to their profession].		1987	260442
[sensory components of optokinetic nystagmus in exposure to the action of angular accelerations].	the relationship between the vestibular and optokinetic nystagmus was investigated using a special vestibulooptokinetic trainer. a correlation between the objective index of the angular velocity of the slow component of the optokinetic nystagmus and concomitant sensory reactions responsible for the visual perception of optokinetic stimuli was examined. it was shown that tolerance of the optokinetic system can be characterized by the differential criterion +/-deltaw that is the difference between ...	1987	304506
the clinical utility of ipsilateral stapedius reflex tests.	ipsilateral stapedius reflex testing has been evaluated in 166 patients. it proves of value in defining the state of an ear (1) opposite to a unilateral conductive loss; (2) the less hard-of-hearing ear in the presence of bilateral asymmetrical sensorineural hearing losses where the worse ear has sufficiently severe loss to prevent a contralateral reflex from being elicited; (3) in patients with absent contralateral acoustic reflexes at 500, 1000, and 2000 hz; and (4) in suspected central lesion ...	1987	203715
[reitgjerdet hospital].		1987	260354
[broad caricature--or? bitter pill from a professional patient].		1987	260349
an evaluation of the safety of cefuroxime axetil during six months oral administration to beagle dogs.	the effects of repeated oral administration of cefuroxime axetil were assessed in beagles. the test material, an ester, is hydrolysed following absorption from the intestine to yield the therapeutically active moiety, cefuroxime, together with acetic acid and acetaldehyde; in this study cefuroxime and unhydrolyzed cefuroxime axetil were detected in the blood. cefuroxime axetil was administered twice daily during 27 weeks by gavage of aqueous, suspensions, total daily doses were equivalent to 100 ...	1986	3820342
[assessment of the production of surfactant by type ii alveolocytes during chemotherapy of experimental pulmonary tuberculosis].		1986	3823064
effect of carbon and nitrogen sources on the chemical composition of lipids of rhizopus delemar.	soy bean extract with glucose or oleic acid in the growth medium of rhizopus delemar affected the production of higher values of biomass, total lipids and total glycerides than when ammonium nitrate was used as a source of nitrogen. the highest amounts of biomass (12.35 g/l) and total lipids (310 mg/g dry biomass) were attained in glucose-grown mycelia. the high proportions of total glycerides and unsaturated fatty acids in lipids of rhizopus delemar suggest the utilization of such lipid materia ...	1986	3825190
primary rhabdomyosarcoma combined with chronic paragonimiasis in the cerebrum: a necropsy case and review of the literature.	a necropsy case of a primary rhabdomyosarcoma with chronic paragonimiasis in the cerebrum of a 68-year-old man is reported. the clinical data showed a right hemiplegia and dysarthria which became lethal in 6 months even though operation and radiation therapy were performed. computed tomography revealed a large low-density area associated with the peripheral enhancement in the left basal ganglia, and multiple conglomerated calcified masses in the left temporal and occipital lobes. biopsied and ne ...	1986	3825517
similarity principles and intrinsic geometries: contrasting approaches to interspecies scaling.	we criticize standard allometric approaches on the grounds that they emphasize scaling to one variable at a time, whereas chemically reactive hydrodynamic systems involved in pharmacokinetic phenomena are of higher dimension. we show that attempts based on mechanical similitude to set a dosage that would be equivalent across species (for example, from mouse to humans) lead to ambiguous results. another failing of standard allometry may be its incapability to accommodate the neoteny of homo sapie ...	1986	3820095
structural elucidation of a water-insoluble glucan produced by a cariogenic oral streptococcus.	the structure of a water-insoluble polysaccharide produced by the d-glucosyl-transferase of streptococcus mutans 6715 has been elucidated through periodate oxidation, smith degradation, dextranase digestion, concanavalin a binding studies, and methylation combined with g.l.c.-m.s. analysis. these studies show that the d-glucan is comprised of 67% alpha-(1----3) linkages in a contiguous backbone with the remaining 33% as alpha-(1----6) linkages, possibly as linear residues extending from alpha-(1 ...	1986	3815409
[place of endoscopy in anorectal malformations].	miniaturised cystoscope allows exploration in neonates, but in males, it may be difficult and dangerous. recto-urinary fistulae are generally recto-prostatic, seldom recto-bulbar. recto-vesical cases were not observed. the fistulous orifice is quite always small and its form is round or ovoid. an anfranctuous and large orifice may be of iatrogenic origin. endoscopic examination is mandatory when recto-urinary fistula is clinically or radiologically suspected and is always necessary before surger ...	1986	3815655
[neuronal organization of conditioned inhibition].		1986	3817182
membrane pores in hypotonically dialyzed sheep erythrocytes remain open after three weeks of storage: entrapment of different stokes radius probes, [14c]sucrose and [3h]inulin.	sheep carrier erythrocytes were prepared from dialyzed cells stored for 3 weeks. the initial pore size in freshly dialyzed cells exceeds the stokes radius of that for hemoglobin. hypotonically dialyzed erythrocytes are then very stable in a porous state. two probes of different stokes radius were used to determine the relative size of the pores. sheep erythrocytes entrap inulin to a greater extent than sucrose, a much smaller molecule. with storage, a greater fraction of dialyzed cells become im ...	1986	3814359
surface localization of sialic acid on actinomyces viscosus.	this study reports the presence of sialic acid in actinomyces viscosus strains t14v and t14av. mild acid hydrolysis of whole organisms released a compound which reacted positively in the periodate-thiobarbituric acid, direct ehrlich's and resorcinol assays, and which co-chromatographed on paper with authentic n-acetylneuraminic acid. strain t14v contained 10-fold greater concentrations of sialic acid than did strain t14av. sialic acid content was dependent upon the stage of growth of the culture ...	1986	3655719
purification and properties of fibrin high-affinity urokinase from human urine.		1986	3811788
the effects of ornipressin and adrenaline on lignocaine nerve blocks.	an electrophysiological method measuring nerve conduction following the electrical stimulation of a sciatic nerve branch in anaesthetised rats was used to evaluate under strictly controlled conditions the effects of 1:100,000 adrenaline and of 0.03 iu x ml-1 ornipressin on the speed of onset, depth and duration of lignocaine anaesthesia. it was shown that compared with plain lignocaine, lignocaine with ornipressin produced shorter onset of anaesthesia and improved its depth and duration. adding ...	1986	3811808
histomorphometry of masticatory muscles in the muscular dystrophic mouse.	cross sections of normal and dystrophic digastric, masseter and temporalis muscles from 7-week-old mice were studied by histomorphological and histomorphometrical methods in the light microscope. the histomorphological part of the study revealed marked differences in morphology between normal and dystrophic muscles. mutual differences between the dystrophic muscles were also observed. comparisons of the parameters chosen for the histomorphometrical part of the study, i.e., cell size and number o ...	1986	3811823
simultaneous recording of uterine and tubal motility during utero-tubal insufflation in monkeys.	one main cause of female infertility is the tubal factor, and interest in the role and function of the fallopian tube has increased our knowledge about tubal infertility. in this study in monkeys, cynomolgus (macaca fascicularis), the tubal and uterine motility was recorded with a millar microtransducer. the recordings were made during uterotubal, uterine as well as tubal insufflation with gas. tubal activity patterns varied with the phase of the menstrual cycle. the kymograms made during gas in ...	1986	3811846
developmental arrest of haemonchus contortus in sheep treated with a corticosteroid.		1986	3804575
relationship between amino acid composition of diet and plasma cholesterol level in growing rats fed a high cholesterol diet.	the effects of dietary sulfur-containing amino acids and glycine on plasma cholesterol level were studied in rats fed amino acid mixture diets containing cholesterol. the relationship between the amino acid composition of dietary proteins and plasma cholesterol levels was also investigated in rats fed diets containing various kinds of protein such as casein, egg albumin, pork protein, fish protein, corn gluten, wheat gluten and soy protein. feeding the amino acid mixture corresponding to casein ...	1986	3806255
a contribution to indirect ophthalmotonometry in beagles.	a test of suitability of the electroimpression tonometer from fritz schwarzer gmbh, munich, for measuring intraocular pressure in dogs was performed. intraocular pressure of 63 clinically healthy english beagles was measured in both eyes using the instrument with different plunger weights. intraocular pressure and volume of corneal depression during measurement were determined as a function of the plunger weight from readings on the tonometer with the aid of friedenwald's tables (2). using fried ...	1986	3807468
[diagnosis of borrelia infections is an all-year-round problem as the serological examination of the cases from 1985 shows].		1986	3807483