Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| modulation of monocrotaline-induced hepatic genotoxicity in rats. | monocrotaline (mct), a hepatotoxic/hepatocarcinogenic pyrrolizidine alkaloid (pa) induced dna-dna interstrand crosslinks in a dose-dependent manner through 30 mg/kg. hepatic cytochrome p-450 has been shown to bioactivate mct to pyrrole derivatives which are thought to be responsible for these genotoxic lesions. we have hypothesized these lesions to be related to the adverse hepatic actions of mct and other pas. studies reported here investigated the effect of phenobarbital, a p-450 inducer, 2-di ... | 1987 | 3102099 |
| the protein receptor for cholerabacteriophage phi 149. | choleraphage phi 149 receptor activity was found in the outer membrane (om) protein of vibrio cholerae 154. receptor protein for phage phi 149 was separated from trypsin-treated om on a sephadex g-100 column. of the three peaks obtained, phage receptor activity was noted only in peak ii. sds-page showed that the mr of the protein was 35,000. the protein was heat-labile and protease-sensitive. the specificity of this protein as choleraphage phi 149 receptor was investigated by carrying out a prot ... | 1987 | 3104086 |
| resolution of radiolabeled molecular species of phospholipid in human platelets: effect of thrombin. | resolution of individual molecular species of human platelet 1,2-diradyl-sn-glycero-3-phosphocholines and 1,2-diradyl-sn-glycero-3-phosphoethanolamines by reverse phase high pressure liquid chromatography (hplc) allowed a thorough analysis of those phospholipids labeled with [3h]arachidonic acid. approximately 54% and 16% of the total incorporated radiolabel was found in choline glycerophospholipids and ethanolamine glycerophospholipids, respectively, with ca. 90% of this being found in the 1,2- ... | 1987 | 3104714 |
| increased growth hormone response to clonidine in 6-hydroxydopamine-treated rats. | alpha 2-adrenergic receptors mediate adrenergic stimulation of growth hormone (gh) secretion in the rat. the gh response to the alpha 2-adrenergic agonist clonidine has thus been used as an index of alpha 2-adrenergic receptor responsiveness. pharmacologic manipulations known to upregulate alpha 2-adrenergic receptor sensitivity would then be expected to result in an enhancement of the gh response to clonidine. to test this hypothesis, rats were injected in the lateral ventricle with either 6-hy ... | 1987 | 3104956 |
| differences between saccharomyces cerevisiae and bacillus subtilis in secretion of human lysozyme. | saccharomyces cerevisiae secreted human lysozyme in the medium as an active form when the signal peptides of chicken lysozyme and a chicken lysozyme-aspergillus awamori glucoamylase hybrid were used, whereas it did not synthesize any human lysozyme protein by using the signal peptide of a. awamori glucoamylase. the secreted lysozyme was easily purified and crystallized. on the other hand, bacillus subtilis secreted an inactive human lysozyme, which seemed to have incorrect disulfide bonds, with ... | 1987 | 3109419 |
| differences between saccharomyces cerevisiae and bacillus subtilis in secretion of human lysozyme. | saccharomyces cerevisiae secreted human lysozyme in the medium as an active form when the signal peptides of chicken lysozyme and a chicken lysozyme-aspergillus awamori glucoamylase hybrid were used, whereas it did not synthesize any human lysozyme protein by using the signal peptide of a. awamori glucoamylase. the secreted lysozyme was easily purified and crystallized. on the other hand, bacillus subtilis secreted an inactive human lysozyme, which seemed to have incorrect disulfide bonds, with ... | 1987 | 3109419 |
| experimental vibrio el-tor infected water fish breeding. stressing reservoir establishment in loach and finless eels. | 1987 | 3109842 | |
| analogs of 9-deazaadenosine: potent inhibitors of methylthioadenosine phosphorylase. | 1987 | 3111473 | |
| anemia-inducing substance (ais) in advanced cancer: inhibitory effect of ais on the function of erythrocytes and immunocompetent cells. | the effects of anemia-inducing substance (ais), found in the plasma of tumor-bearing subjects, on red blood cells (rbc) and cellular immunity were examined. the results obtained may be summarized as follows: 1) the osmotic resistance and the deformability of rbc were decreased in patients with terminal cancer. 2) normal human rbc were made less deformable and their membrane was made fragile by treatment with cachectic plasma from those patients, and these changes in physical properties were irre ... | 1987 | 3112075 |
| distinct culture requirements for activation and proliferation of human peripheral blood b lymphocytes by staphylococcus aureus cowan strain and growth factors. | the concentration of fetal calf serum (fcs) and the culture period were the crucial culture conditions in measuring b cell growth factor (bcgf) and il-2 activity in vitro. higher concentrations of fcs (10-15%) significantly inhibited bcgf activity; whereas, lower concentrations of fcs (less than 2.5%) were not sufficient for the response to il-2. kinetic experiments showed that the culture period for bcgf should be shorter than that for il-2, while bcgf in combination with il-2 induced a synergi ... | 1987 | 3112237 |
| [drug-resistance and transferable r plasmids in vibrio cholerae o-1 and non o-1, v. fluvialis and v. parahaemolyticus recently isolated from human sources]. | 1987 | 3112272 | |
| [in vitro antibacterial activity of new derivatives of pyridonecarboxylic acid, norfloxacin, ofloxacin, enoxacin and ciprofloxacin, against vibrio cholerae o-1]. | 1987 | 3112282 | |
| studies on transmission of human non-a, non-b hepatitis to marmosets. | two sera obtained from four healthy blood donors, which caused non-a, non-b post-transfusion hepatitis in two recipients, were experimentally inoculated into nine marmosets. three of seven marmosets developed acute hepatitis characterized by the elevation of serum concentrations of glutamic pyruvic transaminase (gpt) and/or isocitric dehydrogenase (icd) 8-11 weeks after inoculation. four of seven showed histopathological changes of acute hepatitis in liver biopsy specimens during the biochemical ... | 1987 | 3112304 |
| structural and immunochemical characterization of the o-haptens of brucella abortus lipopolysaccharides from strains 19 and 2308. | the o-haptens of the major fraction (f5a) of b. abortus (strains 2308 and 19) membrane bound smooth lipopolysaccharide (slps) were prepared by hydrolysis of f5a native slps in 1% acetic acid at 100 degrees c for 2 h. after hydrolysis, o-haptens were separated from lipid a-protein complex by centrifugation, and from small fragments by ultrafiltration of molecular weight cut-off (mwco) 1.0 x 10(3). these carbohydrate haptens were identified by precipitin-inhibition assay and further fractionated b ... | 1987 | 3114617 |
| schistosoma mansoni: autoradiographic tracking studies of isotopically-labelled challenge parasites in naive and vaccinated cba/ca mice. | the migration of isotopically-labelled challenge parasites of schistosoma mansoni in naive cba/ca mice, and cba/ca mice vaccinated 4 weeks previously with about 600 radiation-attenuated cercariae, has been followed by means of compressed organ autoradiography. in naive mice, only 16% of the challenge parasites failed to migrate from the skin to the lungs, whereas up to half of the individuals that succeeded in reaching the pulmonary vasculature did not move on to the liver. the tracking techniqu ... | 1987 | 3114702 |
| implication of ornithine decarboxylase and polyamines in pancreatic growth of neonatal rats. | the current study examines the effects of alpha-difluoromethylornithine (dfmo), an irreversible ornithine decarboxylase inhibitor, on pancreatic growth and development of rat neonates. newborn rats were given daily subcutaneous injections of 300 or 500 mg kg-1 dfmo and killed after 7, 14, 21, and 28 days of treatment. pancreatic weights and dna, rna, protein, amylase and chymotrypsin total contents (per pancreas) and concentrations were evaluated at the end of each period. inhibition of body wei ... | 1987 | 3114741 |
| delay of development of transmural irreversible ischaemic injury in canine myocardium. | during the course of experimentally induced myocardial ischaemia affected tissue initially suffers reversible ischaemic injury or, if ischaemia persists, injury of increasing severity before becoming irreversibly damaged. this state is characterized by tissue necrosis and referred to as myocardial infarction. the purpose of this study was to investigate whether it is possible to delay or perhaps even prevent the development of irreversible ischaemic injury. ischaemia was induced by coronary arte ... | 1987 | 3114945 |
| hypophosphataemia: a feature of malaria? | 1987 | 3115481 | |
| [central mechanisms of the development of ischemic disorders of heart rhythm]. | the activity of afferent and internuncial neurons of the bulbar cardiovascular centre (bcvc) was evaluated, using microelectrodes, in conditions of serotonin microinjections, altered blood gas composition and sensomotor cortical stimulation, in acute experiments in cats and rabbits. the afferent flow from ischemized myocardium was examined at the level of nodular-ganglion neurons. cortical stimulation, changed blood o2 and co2 proportions and the afferent message related to impaired coronary flo ... | 1987 | 3116317 |
| [comparative in vitro activity of 10 new 4-quinolones against enteropathogenic bacteria]. | the susceptibility has been determined of 169 shigella spp., 93 salmonella spp., 68 yersinia enterocolitica, 34 vibrio cholerae 0:1, and 34 campylobacter jejuni, isolated in central africa and in belgium, to ten fluoroquinolones: ciprofloxacin, ofloxacin, norfloxacin, pefloxacin, enoxacin, amifloxacin, ci-934, a-56619, a-56620 and ro 23-6240. all quinolones were active against the strains tested, showing an mic90 between 0.004 mg/l and 2 mg/l for strains susceptible to nalidixic acid and an mic9 ... | 1987 | 3116489 |
| intestinal epithelial function and villus surface area in rats with bile fistulae. | we have previously found reduced absorption of vitamin b12 in rats with choledochocolic fistulae. to investigate whether the reduction is caused by epithelial dysfunction or mucosal hypoplasia, choledochocolic fistulae were made in 11 rats, whereas 10 rats were sham-operated. the epithelial function was evaluated 9 days later by measuring the uptake of 57cob12 and glucose in perfused intestinal segments and by determining the activities of 11 mucosal enzymes. hypoplasia was investigated by perfo ... | 1987 | 3116662 |
| antimicrobial activity of lysozyme against bacteria involved in food spoilage and food-borne disease. | egg white lysozyme was demonstrated to have antibacterial activity against organisms of concern in food safety, including listeria monocytogenes and certain strains of clostridium botulinum. we also found that the food spoilage thermophile clostridium thermosaccharolyticum was highly susceptible to lysozyme and confirmed that the spoilage organisms bacillus stearothermophilus and clostridium tyrobutyricum were also extremely sensitive. several gram-positive and gram-negative pathogens isolated f ... | 1987 | 3118808 |
| combined effects of the mycotoxins aflatoxin b1 and cyclopiazonic acid on sprague-dawley rats. | this study was conducted to determine whether exposure to cyclopiazonic acid (cpa) and aflatoxin b1 (afb1) would alter the toxicity associated with exposure to either toxin individually. groups of male rats were administered 0, 0.1 or 4.0 mg cpa/kg body weight/day intragastrically (three groups per dose level) for three consecutive days and 30 min after each of these cpa doses the rats were dosed by gavage with 0, 0.1 or 2.0 mg afb1/kg body weight/day. six of the 12 rats given each of these nine ... | 1987 | 3121482 |
| a cellular protein binds to a conserved sequence in the adenovirus type 2 enhancer. | a sensitive gel retention assay has been utilized to detect proteins from uninfected hela nuclei which interact with the adenovirus type 2 enhancer. this assay has been employed to monitor fractionation of nuclear extracts. three enhancer binding factors were resolved by chromatography on deae-sepharose and one of the factors was further purified by chromatography on heparin-sepharose. dnase protection experiments have shown that the heparin-sepharose fraction contains a factor which binds predo ... | 1987 | 3031610 |
| evolution of localization of reactions of adenosine triphosphatase (mg++-atp-ase), 5'nucleotidase (5'nt), alkaline phosphatase (ap), and acid phosphatase (acp) in developing rat testis. ii. after cdcl2 treatment. | the described experiments show the influence of a single dose of cadmium chloride (1.5 mg cdcl2/kg body weight applied intraperitoneally) on development of the male gonads from the 1st d of post-fetal life to 1.5 a of life. in the case of the enzymes triggering transportation processes, adenosine triphosphatase stimulated by mg++ (mg++-atp-ase), alkaline phosphatase (ap), and 5'nucleotidase (5'nt), a considerable damages begin to appear in the 15th d of life whereas in the case of acid phosphata ... | 1987 | 3031915 |
| [effect of cholera enterotoxin on carbohydrate metabolism of the liver and small intestine mucosa in the rabbit]. | changes in carbohydrate metabolism were studied in the isolated intestinal loops of rabbits during secretory diarrhea, induced by cholera enterotoxin. glucose synthesis level in the small intestinal mucosa and liver was measured by isotope technique, using l-alanine as a precursor. intestinal gluconeogenesis, calculated per mg of protein, appeared to be twice higher than in the liver of fasting rabbits. cholera enterotoxin administration enhanced gluconeogenesis in the liver by 60%, as compared ... | 1987 | 3032299 |
| role of postnatal gonadal function in the determination of thyrotropin (tsh) releasing hormone-induced tsh response in adult male and female rats. | permanent effects of postnatal gonadal function on the hypothalamo-pituitary-thyroid axis were examined in male and female rats of the wistar-imamichi strain. animals were used at the age of about 10 weeks. neonatally castrated (nc) males showed a significantly higher plasma tsh response to trh (10 micrograms/kg bw, ip) than males castrated at 1, 2, 3, 4, or 6 weeks of age. the tsh response in intact males was similar to that seen in nc males. neonatal androgenization of nc males with 100 microg ... | 1987 | 3032567 |
| growth hormone-releasing factor-44 specificity for components of somatotroph and lactotroph immediate release pool substructures. | rat somatotroph and lactotroph hormone storage is divisible into at least two functional compartments: an immediate release pool (irp) and a pool that responds to prolonged stimulation. an irp substructure has been defined by release in response to potassium ion (k+), prostaglandin e1 (pge1), and bu2camp. the somatotroph irp is expandable; the lactotroph irp is fixed in size. the present experiments examined which irp components contribute to the rapid release of stored gh in response to gh-rele ... | 1987 | 3032568 |
| presence of gonadotropin-releasing hormone-like proteins in bovine and ovine ovaries. | recently, the rat ovary was shown to contain significant levels of a gnrh-like protein, but no detectable gnrh. in the present studies, extracts of bovine ovaries and ovine corpora lutea were examined for their content of both gnrh-like protein and gnrh. the gnrh-like proteins were detected with a rat ovarian membrane radioreceptor assay, and gnrh was detected with a specific gnrh ria. the biological activity of the gnrh-like protein was evaluated with a rat luteal cell assay. gnrh-like activity ... | 1987 | 3032569 |
| cyclic amp phosphodiesterase in thermomonospora curvata. | cyclic amp phosphodiesterase (pde; ec 3.1.4.17) in thermomonospora curvata was purified and characterized. fractionation of cell extracts by ion-exchange and size-exclusion chromatography revealed four pde isozymes, which differed markedly in molecular weight, theophylline sensitivity, ph optima, and substrate affinity. although the enzyme was labile after purification, total recovery of pde activity was fivefold that of the crude extract. pde biosynthesis appeared sensitive to the growth phase, ... | 1987 | 3032914 |
| maturation antigen of the mouse sperm flagellum: ii. origin from holocrine cells of the distal caput epididymis. | during epididymal transit, the mouse sperm flagellum acquires a surface glycoprotein (sma4) from epididymal fluid that functions as a sperm antiagglutinin. to determine the origin of this molecule, testes and epididymides of male mice were sectioned for light microscopy and stained with wheat germ agglutinin (wga)-peroxidase, a probe that has been used previously to examine the biology of sma4. wga reactivity was localized to the cytoplasm in a small population of cells in the distal caput epidi ... | 1987 | 3034104 |
| molecular cloning of a xylanase gene from bacteroides succinogenes and its expression in escherichia coli. | a gene coding for xylanase synthesis in bacteroides succinogenes was isolated by cloning, with escherichia coli hb101 as the host. after partial digestion of b. succinogenes dna with sau3a, fragments were ligated into the bamhi site of pbr322 and transformed into e. coli hb101. of 14,000 colonies screened, 4 produced clear halos on remazol brilliant blue-xylan agar. plasmids from two stable clones recovered exhibited identical restriction enzyme patterns, with the same 9.4-kilobase-pair (kbp) in ... | 1987 | 3034151 |
| calmodulin-mediated cadmium inhibition of phosphodiesterase activity, in vitro. | ion-stripped bovine brain calmodulin (cam) binds 4 moles cd2+ as well as 4 moles ca2+ per mole protein, with similar affinity; in the presence of 1 mm mg2+ the molar binding ratio of cam for ca2+ decreased to 3, the apparent k0.5 for ca2+ nearly doubled, but the binding characteristics of cam for cd2+ were not changed. saturating concentrations ca2+ did not affect the molar binding ratio of cam for cd2+, but increased the apparent k0.5 for cd2+; vice versa, saturating concentrations cd2+ decreas ... | 1987 | 3034196 |
| effect of recombinant human interferon gamma against human cytomegalovirus. | escherichia coli-derived human interferon-gamma (rifn-gamma) inhibited the replication of human cytomegalovirus (hcmv) synergistically when combined with ifn-alpha. the induction of hcmv dna polymerase was inhibited in rifn-gamma-treated cells. it is suggested that the induction of 2-5 a synthetase does not play an important role in the anti-hcmv actions of ifns. | 1987 | 3034215 |
| radiation-induced dna damage and its repair. | application of modern methods of organic chemistry and recombinant dna technologies has provided new insights in the field of dna radiation damage and its repair. an overview of the chemical nature of the lesions inflicted on dna by ionizing radiation is presented. the structures of 29 different dna modified base or sugar residues are shown in comprehensive formation schemes. a fraction of radiation-induced modified bases is spontaneously released from the dna chain during irradiation. another p ... | 1987 | 3034813 |
| radiation-induced dna damage and its repair. | application of modern methods of organic chemistry and recombinant dna technologies has provided new insights in the field of dna radiation damage and its repair. an overview of the chemical nature of the lesions inflicted on dna by ionizing radiation is presented. the structures of 29 different dna modified base or sugar residues are shown in comprehensive formation schemes. a fraction of radiation-induced modified bases is spontaneously released from the dna chain during irradiation. another p ... | 1987 | 3034813 |
| active lambda and kappa antibody gene rearrangement in abelson murine leukemia virus-transformed pre-b cell lines. | the two abelson murine leukemia virus (a-mulv)-transformed cell lines, bm18-4 and abc-1, undergo immunoglobulin l-chain gene recombination during passage in tissue culture. bm18-4 cells are capable of kappa gene recombination, whereas abc-1 cells are capable of both kappa and lambda gene recombination. the expression of h chains is apparently not necessary for continuing l chain gene recombination in either of these cells, although h-chain expression may have been involved in the initiation of l ... | 1987 | 3035056 |
| effect of exogenous gangliosides on amino acid uptake and na+, k+-atpase activity in superior cervical and nodose ganglia of rats. | the effects of some gangliosides on active uptake of nonmetabolizable alpha-aminoisobutyric acid (aib) and na+, k+-atpase and ca2+, mg2+-atpase activities in superior cervical ganglia (scg) and nodose ganglia (ng) excised from adult rats were examined during aerobic incubation at 37 degrees c for 2 h. in ng, amino acid uptake was greatly accelerated with the addition of galactosyl-n-acetylgalactosaminyl-[n-acetylneuraminyl]-galactosylgluc osyl ceramide (gm1) (85%) and also with n-acetylgalactosa ... | 1987 | 3035095 |
| binding studies of dermorphin and its l-form on rat brain opioid receptors. | it is well known dermorphin is a potent and long-acting opioid peptide while its synthetic l-form is almost completely devoid of biological activity. we investigated whether the l-ala2 residue might affect the affinity of the compound for opioid receptors or make [l-ala2] dermorphin more sensitive to metabolic degradation. dermorphin and [l-ala2] dermorphin were assayed in [3h]naloxone binding to opioid receptors in rat brain preparations in the absence and presence of peptidase inhibitors besta ... | 1987 | 3035583 |
| chronic food restriction and the circadian rhythms of pituitary-adrenal hormones, growth hormone and thyroid-stimulating hormone. | adult male sprague-dawley rats were subjected to food restriction so that they ate 65% of food ingested by control rats. while control rats had free access to food over the 24-hour period, food-restricted rats were provided with food daily at 10 a.m. the experimental period lasted for 34 days. on day 35, rats from both experimental groups were killed at 08.00, 11.00, 14.00, 24.00 and 02.00 h. food restriction modified the circadian rhythms of acth and corticosterone. in addition, total circulati ... | 1987 | 3035995 |
| chronic food restriction and the circadian rhythms of pituitary-adrenal hormones, growth hormone and thyroid-stimulating hormone. | adult male sprague-dawley rats were subjected to food restriction so that they ate 65% of food ingested by control rats. while control rats had free access to food over the 24-hour period, food-restricted rats were provided with food daily at 10 a.m. the experimental period lasted for 34 days. on day 35, rats from both experimental groups were killed at 08.00, 11.00, 14.00, 24.00 and 02.00 h. food restriction modified the circadian rhythms of acth and corticosterone. in addition, total circulati ... | 1987 | 3035995 |
| [expressing plasmid vectors on the basis of escherichia coli beta-galactosidase gene fragments]. | with the use of synthetic dna fragments, a set of new plasmid vectors has been obtained. the vectors provided high level expression of peptides and small proteins in e. coli as fusions with fragments of beta-galactosidase of various length. these vectors were used to achieve expression of a synthetic gene for a functionally active fragment of bacteriorhodopsin. the yields of hybrid proteins consisting of beta-galactosidase and bacteriorhodopsin fragments were in the range of 5-30% from the total ... | 1987 | 3036168 |
| isolation of a mouse heat-shock gene (hsp68) by recombinational screening. | we have used cloned fragments from a drosophila melanogaster hsp70 gene and a mouse hsp68 cdna in recombinational screens of mouse genomic libraries. using the mouse probe we have isolated two overlapping recombinant lambda phages comprising 22 kb of cloned dna. southern analysis has localized the homology with the drosophila hsp70 coding region to a 2.2-kb fragment containing the mouse heat-shock gene. insertion accompanying recombinational screening can disrupt interesting sequences; we have o ... | 1987 | 3036653 |
| extracellular proteins of vibrio cholerae: molecular cloning, nucleotide sequence and characterization of the deoxyribonuclease (dnase) together with its periplasmic localization in escherichia coli k-12. | the gene encoding the extracellular dnase of vibrio cholerae was cloned into escherichia coli k-12. a maximal coding region of 1.2 kb and a minimal region of 0.6 kb were determined by transposon mutagenesis and deletion analysis. the nucleotide sequence of this region contained a single open reading frame of 690 bp corresponding to a protein of mr 26,389 with a typical n-terminal signal sequence of 18 aa which, when removed, would give a mature protein of mr 24,163. this is in good agreement wit ... | 1987 | 3036665 |
| identification of human rotaviruses in stools from children with gastroenteritis. | 1987 | 3037006 | |
| itraconazole treatment of experimental systemic candidiasis in male rats. | after intravenous infection with candida albicans, rats received daily doses of itraconazole for 3 days. all rats receiving 2.5 mg kg-1 day-1 survived while all rats receiving sham-treatment died. with subsequent reduction of the itraconazole dose to 0.63 mg kg-1 day-1, no survival occurred and mortality rates equalled those of the control group. | 1987 | 3037058 |
| itraconazole treatment of experimental systemic candidiasis in male rats. | after intravenous infection with candida albicans, rats received daily doses of itraconazole for 3 days. all rats receiving 2.5 mg kg-1 day-1 survived while all rats receiving sham-treatment died. with subsequent reduction of the itraconazole dose to 0.63 mg kg-1 day-1, no survival occurred and mortality rates equalled those of the control group. | 1987 | 3037058 |
| [construction of recombinant plasmids encoding the biosynthesis of the beta-subunit of cholera toxin]. | the structure of the cholera toxin operon and the location of a and b toxin subunits have been studied by the southern blot hybridization on filters. the gene coding for the synthesis of the cholera toxin b-subunit has been cloned in the vector plasmid pbr322. the structural gene of a-subunit has been partially deleted by the restriction endonuclease bal31 digestion. the size of the 250 b. p. deletion has been defined by electron microscopy. the production of the cholera toxin b-subunit in esche ... | 1987 | 3037359 |
| evidence for a nigro-pulvinar-lateralis posterior complex projection in the cat using horseradish peroxidase neuronal retrograde technique. | the possible existence of a direct projection from the substantia nigra to the pulvinar-lateral posterior complex (pul-lp) was investigated in the cat by using the horseradish peroxidase technique. in particular horseradish peroxidase was injected in the pul-lp of 8 animals, either unilaterally or bilaterally. tissue sections obtained from the cat's brain 24-48 hrs. after injection were prepared according to mesulam's method as slightly modified by the authors. retrogradelly labelled neurons wer ... | 1987 | 3038046 |
| complete amino acid sequence of cytochrome c551 from erythrobacter species strain och 114. | the complete amino acid sequence of cytochrome c551 isolated from an aerobic photosynthetic bacterium, erythrobacter sp. strain och 114, was determined. the cytochrome molecule was composed of a total of 119 amino acid residues and its molecular weight including heme was calculated to be 13,235. the sequence was (sequence: see text). its molecular weight indicates that this cytochrome is of the l-type. sequence alignment with other bacterial cytochromes c shows that this cytochrome is similar to ... | 1987 | 3038859 |
| adherence of streptococcus mutans to implant materials. | the adherence of streptococcus mutans omz-176 to six implant materials (poly-crystal alumina, single-crystal alumina, titanium alloy, cobalt-chromium-molybdenum alloy, hydroxyapatite, and heat-curing polymethylmethacrylate resin) was studied in vitro. the change of free energy, which corresponds to the adherence process, was also evaluated for hydrophobic interaction. adherence of s. mutans to poly-crystal alumina was lower than adherence to other materials. the adherence of s. mutans to the tes ... | 1987 | 3038919 |
| modulation of fibronectin gene expression in chondrocytes by viral transformation and substrate attachment. | chicken vertebral chondrocytes, which normally grow in suspension, synthesize large amounts of cartilage extracellular matrix proteins, but little fibronectin. we have analyzed the effects of both substrate attachment and transformation with a temperature-sensitive mutant of rous sarcoma virus on fibronectin gene expression in these cells. our experiments show that viral transformation increases fibronectin synthesis to a greater extent than substrate attachment. furthermore, transformed chondro ... | 1987 | 3038928 |
| two-year survey of etiologic agents of diarrheal disease at san lazaro hospital, manila, republic of the philippines. | the prevalence of bacterial pathogens and rotavirus in 2,908 patients with diarrhea who were admitted to san lazaro hospital in manila in 1983 and 1984 was determined. one or more enteric pathogens were isolated or detected in samples from 1,698 (58.4%) patients. isolation rates for the various enteropathogens were as follows: rotavirus, 30.6%; shigella spp., 11.6%; salmonella spp., 9.2%; enterotoxigenic escherichia coli (1983 only), 7.8%; vibrio cholerae biotype eltor, 3.8%; non-o1 v. cholerae, ... | 1987 | 3038946 |
| the nucleotide sequence and genome organization of bovine papillomavirus type 4. | the nucleotide sequence of bovine papillomavirus type 4 (bpv-4) was determined. the viral genome is 7261 base pairs long. several overlapping open reading frames (orfs) have been identified both on the basis of amino acid comparison with other papillomaviruses and on their transcriptional pattern. eight early orfs (e1 to 8) were recognized, coding for dna replication and cell transformation functions, and three late orfs (l1 to 3), coding for structural proteins. like the e5 orf of human papillo ... | 1987 | 3039043 |
| establishment of a human t-cell hybridoma that produces human macrophage activating factor for superoxide production and translation of messenger rna of the factor in xenopus laevis oocyte. | human monoblast-like histiocytic lymphoma cell line u937 was induced by a macrophage activating factor for o2- production (maf-o) to produce o2- in response to phorbol myristate acetate stimulation. a maf-o-producing human t-cell hybridoma, f4-29-4, was established which was also found to produce macrophage activating factor for glucose consumption (maf-g) and colony stimulating factor (csf) when assayed against mouse bone marrow cells. maf-o could be successfully separated from csf but not from ... | 1987 | 3039355 |
| establishment of a human t-cell hybridoma that produces human macrophage activating factor for superoxide production and translation of messenger rna of the factor in xenopus laevis oocyte. | human monoblast-like histiocytic lymphoma cell line u937 was induced by a macrophage activating factor for o2- production (maf-o) to produce o2- in response to phorbol myristate acetate stimulation. a maf-o-producing human t-cell hybridoma, f4-29-4, was established which was also found to produce macrophage activating factor for glucose consumption (maf-g) and colony stimulating factor (csf) when assayed against mouse bone marrow cells. maf-o could be successfully separated from csf but not from ... | 1987 | 3039355 |
| antagonist effects of the enantiomers of 3-ppp towards alpha 1-adrenoceptors coupled to inositol phospholipid breakdown in the rat cerebral cortex. | the effects of the two enantiomers of 3-ppp upon alpha 1-adrenergic and muscarinic receptors coupled to the inositol phospholipid (pi) breakdown response have been investigated. 3-ppp(-) and 3-ppp(+) were found to antagonize the noradrenaline (10 microm)-stimulated pi breakdown in rat cerebral cortical miniprisms with ic50 values of 18 and 61 microm, respectively. the dopamine receptor antagonists haloperidol and raclopride were also antagonists, with ic50 values of 0.4 and 25 microm, respective ... | 1987 | 3039482 |
| the choice of opioid receptor subtype in isolated preparations by ohmefentanyl. | ohmefentanyl has significant inhibitory actions on the electrically evoked contractions of guinea pig ileum and mouse vas deferens. their ic50 values are 0.15 nm and 0.89 nm, respectively. in the guinea pig ileum and the mouse vas deferens, both mu-antagonist naloxone and (mu + kappa)-antagonist mr. 2266 antagonize readily the agonist action of ohmefentanyl, indicating that ohmefentanyl acts on mu-receptors in the guinea pig ileum and the mouse vas deferens. like other mu-agonists, ohmefentanyl ... | 1987 | 3039656 |
| directly observed 15n nmr spectra of uniformly enriched proteins. | the proteins cytochrome c2, cytochrome c', and ribulosebisphosphate carboxylase/oxygenase from rhodospirillum rubrum were enriched in 15n by growth of the organism on 15nh4cl. the proteins were purified to homogeneity and studied by 15n nmr. longitudinal and transverse relaxation times as well as the nuclear overhauser effects were determined for various groups of the proteins which vary in molecular weight from 13,000 to 114,000. the values of these parameters for the amide resonances or for gr ... | 1987 | 3040083 |
| comparative organization of nitrogen fixation-specific genes from azotobacter vinelandii and klebsiella pneumoniae: dna sequence of the nifusv genes. | in the facultative anaerobe klebsiella pneumoniae 17 nitrogen fixation-specific genes (nif genes) have been identified. homologs to 12 of these genes have now been isolated from the aerobic diazotroph azotobacter vinelandii. comparative studies have indicated that these diverse microorganisms share striking similarities in the genetic organization of their nif genes and in the primary structure of their individual nif gene products. in this study the complete nucleotide sequence of the nifusv ge ... | 1987 | 3040672 |
| preferential repair of n-acetoxy-acetylaminofluorene lesions in the nuclease-hypersensitive region of simian virus 40. | we exposed simian virus 40-infected cv-1 monkey cells to the carcinogen n-acetoxy-acetylaminofluorene and monitored the removal of lesions from cellular dna and from various regions of viral dna. exposure to 5.5 microm 3h-labeled carcinogen produced 20-80 adducts per 10(6) bases in cellular dna in different experiments. the initial adduct concentration in viral dna was always approximately half that in cellular dna. at various times after treatment, cellular and viral dna, and restriction fragme ... | 1987 | 3040723 |
| examination of cardiac alpha-adrenoceptors from pharmacological responses and radioligand binding. comparison of rat and guinea pig tissues. | the object of this study was to determine suitable experimental conditions for the pharmacological evaluation of cardiac alpha-adrenoceptors. atrial and ventricular preparations of the guinea pig and rat were employed, and the alpha-adrenoceptor responsiveness was compared with the binding of the alpha-adrenoceptor radioligand [3h]prazosin in membranes prepared from these cardiac regions. the experimental variables examined were the pacing frequency, bath temperature, choice of agonist, and card ... | 1987 | 3041119 |
| [transient hiv-antibody positive tests in heart transplantation patients after repeated administration of a cmv immune globulin preparation]. | after repeated administration of relatively high doses of a cytomegalovirus immunoglobulin preparation to two patients after heart transplantation, both the elisa and the immuno-blot tests became temporarily positive (for 21 and 41 days, respectively) to hiv antibodies. the cmv immunoglobulin preparation was demonstrated to have high hiv antibody titres. the latter ran parallel to antibody titres against measles virus, also transferred passively with the immunoglobulin preparation. this makes it ... | 1987 | 3026767 |
| [virus-related gastroenteritis]. | 1987 | 3026769 | |
| gene expression and genetic engineering in the lens. friedenwald lecture. | 1987 | 3026987 | |
| gene expression and genetic engineering in the lens. friedenwald lecture. | 1987 | 3026987 | |
| [aspergillosis following liver transplantation as a hospital infection]. | in the first four weeks after a liver transplantation, there was an invasive aspergillosis with a lethal course in three out of five patients who were treated postoperatively in the same room. the clinical symptoms were very different. one patient was asymptomatic, and the diagnosis could only be made by autopsy. in another patient, pulmonary symptoms, and in the third patient, cerebral symptoms were the most prominent. in the two latter patients, the infection was demonstrated in the sputum and ... | 1987 | 3028750 |
| [aspergillosis following liver transplantation as a hospital infection]. | in the first four weeks after a liver transplantation, there was an invasive aspergillosis with a lethal course in three out of five patients who were treated postoperatively in the same room. the clinical symptoms were very different. one patient was asymptomatic, and the diagnosis could only be made by autopsy. in another patient, pulmonary symptoms, and in the third patient, cerebral symptoms were the most prominent. in the two latter patients, the infection was demonstrated in the sputum and ... | 1987 | 3028750 |
| the chicken carbonic anhydrase ii gene: evidence for a recent shift in intron position. | the complete nucleotide sequence of the coding region of the chicken carbonic anhydrase ii (ca ii) gene has been determined from clones isolated from a chicken genomic library. the sequence of a nearly full length chicken ca ii cdna clone has also been obtained. the gene is approximately 17 kilobase pairs (kb) in size and codes for a protein that is comprised of 259 amino acid residues. the 5' flanking region contains consensus sequences commonly associated with eucaryotic genes transcribed by r ... | 1987 | 3029691 |
| pharmacological modification of pulmonary vascular injury: possible role of camp. | experiments were designed to test the hypothesis that drugs which increase adenosine 3',5'-cyclic monophosphate (camp) in the lung would prevent the pulmonary hypertension and the increase in vascular permeability caused by the infusion of the oxidant lipid peroxide, tert-butyl hydroperoxide (t-bu-ooh), in isolated rabbit lungs perfused with krebs-henseleit buffer. pretreatment with indomethacin or verapamil was also studied, since these drugs block the increase in pulmonary arterial pressure ca ... | 1987 | 3031002 |
| interleukin 2 receptors are expressed by alveolar macrophages during pulmonary sarcoidosis and are inducible by lymphokine treatment of normal human lung macrophages, blood monocytes, and monocyte cell lines. | expression of receptors for il 2 was believed initially to be restricted to t cells after their activation by il 1 and antigen. however, recently il 2 receptors (il 2r) were demonstrated on activated b cells by using an anti-il 2r monoclonal antibody (anti-tac). in this study, we examined the capacity of cultured human alveolar macrophages, blood monocytes, and myelomonocytic (hl-60) or monoblast (u937) cell lines to bind three different anti-il 2r monoclonal antibodies before or after stimulati ... | 1987 | 3097144 |
| atrial natriuretic peptide levels during angiotensin infusion and indomethacin administration are consistent with angiotensin-mediated regulation in man. | low-dose angiotensin ii (ang ii) infusion raised plasma atrial natriuretic peptide (anp) levels only when endogenous renin-angiotensin levels were low, as in aldosterone-producing adenoma. when plasma renin activity (pra) levels rose tenfold following removal of the tumour, low-dose ang ii infusion no longer stimulated anp, but fivefold higher doses did. indomethacin lowered both pra and anp in bartter's syndrome and in normal subjects. the effect of indomethacin on anp is probably not direct, s ... | 1987 | 2965235 |
| [genetic epidemiology of huntington chorea in chile]. | 1987 | 2966430 | |
| protective immunity against vibrio cholerae infection in the rabbit. | the dic model (duodenal inoculation with ligation of the cecum in rabbits) was employed to study experimentally induced cholera and the related protective immunity. duodenal inoculation (di) without ligation of the cecum with live v. cholerae organisms did not cause any disease symptom but induced protection against subsequent challenges with homologous and heterologous organisms for up to 24 months. after 30 months this protective immunity began to decrease. a similar protective immunity could ... | 1987 | 2964158 |
| isolation and analysis of escherichia coli mutants that allow increased replication of bacteriophage lambda. | escherichia coli mutants were isolated that supported the growth of a lambda ots and, in at least one case, a lambda bts phage at the normally nonpermissive temperature of 39 degrees c. in one such strain, ots and bts suppression ability appeared to be a function of the guab gene. ots suppression by the mutant guab strain was prevented if high levels of guanine or xanthine were present in the medium. no other base had any effect on ots suppression in this strain. other strains carrying spontaneo ... | 1987 | 2951367 |
| [unexplained dyspnea in systemic diseases. importance of bronchiolo-alveolar lavage]. | 1987 | 2953017 | |
| hyperthyroidism selectively increases oxidative metabolism of slow-oxidative motor units. | the effects of thyroid hormone on the nadh-tetrazolium reductase activity (oxidative metabolism marker) of soleus (slow-oxidative) and tensor fascia lata (fast-glycolytic) motoneurons were determined and compared with changes in a variety of enzyme activities in the corresponding muscle fibers. histochemical assays have demonstrated a selective and qualitative conversion in muscle fiber atpase and quantitative increases of nadh-tetrazolium reductase (oxidative) and mitochondrial alpha-glyceropho ... | 1987 | 2953623 |
| cell surface sialic acid influences tumor cell recognition in the mixed lymphocyte reaction. | the ia+ b cell lymphoma, aktb-1b, fails to stimulate thymic lymphocytes in a one-way mixed lymphocyte reaction unless pretreated with sialidase or inhibitors of n-linked oligosaccharide processing. a comparison of different sialidases and sialyltransferases suggests that the removal of only a subset of total surface sialic acid, rather than net desialylation of the cell surface, is required. three sialidases were compared, including vibrio cholerae (vc) and clostridium perfringens (cp), which wi ... | 1987 | 2953814 |
| the balans chair and its semi-kneeling position: an ergonomic comparison with the conventional sitting position. | recently, the balans chair has been introduced with claims that, because of its semi-kneeling position, individuals will experience decreased low-back pain (lbp) as well as improvement in circulation. this study investigated the validity of these claims. twenty healthy subjects were randomly assigned to one of two groups. group 1 subjects sat in the balans chair for a 30-minute study period and then sat in a conventional office chair for an additional 30-minute period. group 2 subjects were stud ... | 1987 | 2954222 |
| [role of helper t-lymphocytes in modulating the humoral immune response to cholera enterotoxin]. | the role of helper t-lymphocytes in the modulation of humoral immune response to sheep red blood cells with choleragen has been studied in vivo, the populations of cooperating marrow cells, formed in mice under the action of hydrocortisone being used as a model. in adoptive transfer marrow cells, taken from mice on day 12 after thymectomy and from mice previously treated with antithymocyte serum, have proved incapable of humoral immune response. choleragen, similarly to theophylline, normalizes ... | 1987 | 2954344 |
| chromosome changes in human malignancy, including the acute leukemias in down syndrome. | 1987 | 2958882 | |
| time course of recovery of "stunned" myocardium following variable periods of ischemia in conscious and anesthetized dogs. | persistence of regional contractile dysfunction after restoration of blood flow to transiently ischemic myocardium has been well described. to date, most studies have been performed in anesthetized animals. the present investigation compared the time course of recovery of regional segment shortening (percentage of segment shortening) in anesthetized versus conscious dogs subjected to a brief period of total occlusion of the left anterior descending coronary artery. periods of occlusion lasting 5 ... | 1987 | 2959132 |
| comparison of prophylactic tetracycline and clioquinol in a rabbit model of intestinal infection with vibrio cholerae and escherichia coli. | the ability of tetracycline and clioquinol to prevent intestinal colonization of vibrio cholerae and escherichia coli was tested in a rabbit model. in the model 10(10) bacteria are given via oro-gastric tube following intravenous cimetidine and oral sodium bicarbonate and prior to intraperitoneal tincture of opium. eighteen hours after challenge the rabbits are sacrificed, and the numbers of the challenge strain remaining in the jejunum and ileum are determined. tetracycline interrupted the inte ... | 1987 | 2962838 |
| the gene for the atrial natriuretic factor is expressed in the aortic arch. | the gene for atrial natriuretic factor is expressed within the adventitial cells of the rat aortic arch. atrial natriuretic factor transcripts, similar in overall size (1100-1200 nucleotides) and 5'-termini to those found in the atria, were identified in the arch. much lower levels (approximately 10-20%) of these transcripts were present in distal thoracic aorta. atrial natriuretic factor peptide was localized by immunocytochemistry to the adventitia of the arch in regions thought to harbor the ... | 1987 | 2947852 |
| characterization of (ca2+ + mg2+)-atpase of sarcoplasmic reticulum by laser-excited europium luminescence. | the molecular environment of ca2+ translocating sites of skeletal muscle sarcoplasmic reticulum (sr) (ca2+ + mg2+)-atpase has been studied by pulsed-laser excited luminescence of eu3+ used as a ca2+ analogue. interaction of eu3+ with sr was characterized by investigating its effect on partial reactions of the ca2+ transport cycle. in native sr vesicles, eu3+ was found to inhibit ca2+ binding, phosphoenzyme formation, atp hydrolysis activity and ca2+ uptake in parallel fashion. the non-specific b ... | 1987 | 2948822 |
| effects of dietary selenite, selenocystine and selenomethionine on selenocysteine lyase and glutathione peroxidase activities and on selenium levels in rat tissues. | weanling male rats were fed a basal selenium (se)-deficient diet or this diet plus 2 ppm se as either selenite, selenocystine (secys) or selenomethionine (semet) for 9 wk. the rats were killed by decapitation while anesthetized with ether, and tissues were assayed for glutathione peroxidase (gpx) and selenocysteine lyase activities, and for se content. dietary se had no effect upon the activity of tissue selenocysteine lyase. this activity was highest in the liver, followed by kidney, muscle and ... | 1987 | 2950214 |
| [results of examining the population in a region with high morbidity for oral mucosal cancer: precancerous changes]. | interviewing and examination of a population characterized by a high level of morbidity of oral cavity cancer, supposedly induced by the use of nas, established a high incidence of leukoplakia and preleukoplakia at this site which are identified as precancerous lesions. the highest relative risk of oral cavity leukoplakia was found in persons who both chew nas and smoke tobacco (12.4). relative risk of leukoplakia is also elevated in those who either chew nas (5.6) or smoke cigarettes (7.7). thi ... | 1987 | 2950660 |
| [cryptococcal meningitis with human t-cell leukemia virus type i carrier: report of a case]. | 1987 | 2897417 | |
| [an immunological study of human t-cell leukemia virus type i (htlv-i) infection (ii)--radioimmunoprecipitation and sds-polyacrylamide gel electrophoretic analysis of antibody of carriers]. | 1987 | 2897404 | |
| development of aids, hiv seroconversion, and potential co-factors for t4 cell loss in a cohort of intravenous drug users. | a cohort of 334 intravenous (iv) drug users from new york city drug treatment programs were followed over a mean 9-month period. among the 165 who were seropositive at enlistment, four developed clinical aids, for an annual rate of 3%. elevated iga was a significant predictor of developing aids. among 72 subjects who were initially seronegative and who were re-interviewed, four were seropositive at follow-up, for a seroconversion rate of 7% per year among seronegatives. among seropositive subjec ... | 1987 | 2896511 |
| genetic study of piliation in escherichia coli: implications for understanding microbe-host interactions at the molecular level. | 1987 | 2892189 | |
| mechanism of cell invasion by trypanosoma cruzi: importance of sialidase activity. | the sialidase activity of trypomastigotes of trypanosoma cruzi and its relationship to the ability of different stocks of the organism to infect cultured cells was examined. sialidase activity in lysates of trypomastigotes was confirmed and shown to be present in organisms of four different stocks of t. cruzi. in addition, sialidase activity was detected in sera of mice acutely infected with organisms of each of the stocks of t. cruzi examined. erythrocytes from these mice were agglutinated by p ... | 1987 | 2892363 |
| reproductive effects of four phthalic acid esters in the mouse. | these studies compared the reproductive toxicity of four phthalates by a continuous breeding protocol. mice were given diets with diethyl phthalate (dep) (0.0, 0.25, 1.25, or 2.5%), di-n-butyl phthalate (dbp) (0.0, 0.03, 0.3, or 1.0%), di-n-hexyl phthalate (dhp) (0.0, 0.3, 0.6, or 1.2%), or di(2-ethylhexyl) phthalate (dehp) (0.0, 0.01, 0.1, or 0.3%). both male and female cd-1 mice were dosed for 7 days prior to and during a 98-day cohabitation period. reproductive function was evaluated during t ... | 1987 | 3564043 |
| luminal and plasma glucose concentrations on intestinal fluid absorption and lymph flow. | the effect of luminal (gl) and plasma (gp) glucose concentration on intestinal fluid absorption and lymph flow in the rat was studied. when gl was zero, fluid absorption rate (jv), total lymph flow, and "excess lymph flow" (jle) during absorption from krebs-ringer solution was 155 +/- 16, 30 +/- 4, and 11 +/- 4 microliters x cm-1 x h-1, respectively, and jle accounted for 7% of jv. jle was the difference between total lymph flow and basal (nonabsorptive) lymph flow (jlb). in the presence of 28 m ... | 1987 | 3565572 |
| anaphylaxis to cabbage: detection of allergens. | allergy to cabbage and other foods in the brassica family has rarely been observed in man. we report a case of facial and throat swelling in an atopic female after she ingested coleslaw on two separate occasions. she had 4+ reactions to cabbage, mustard plant, cauliflower, and broccoli by skin testing. a rast using cabbage extract was positive for specific ige antibody. analysis of cabbage extract by gel filtration showed five peaks of ultraviolet-absorbing material at 280 nm. allergenic activit ... | 1987 | 3565859 |
| decreased sialic acid content of erythrocytes in patients with aplastic anaemia. | the sialic acid content of erythrocytes from patients with aplastic anaemia was determined and compared with those in patients with several haematological disorders and healthy individuals. the sialic acid was released enzymatically with vibrio cholerae sialidase and quantitated by the thiobarbituric acid method (aminoff, 1961). the sialic acid content of normal erythrocytes was 538 +/- 31 nmol/ml of packed erythrocytes. that of erythrocytes from patients with aplastic anaemia was 480 +/- 35 nmo ... | 1987 | 3567088 |
| comparisons of time intervals and plasma lh concentrations during the ovulatory cycle of broiler breeder hens maintained under either a 24 h light:dark cycle or continuous light. | the possibility that egg production in broiler breeder hens may be increased by selection for reduced oviposition interval under continuous light was investigated by comparing the pattern of pre-ovulatory releases of plasma luteinising hormone (lh) and the associated ovipositions in the same broiler hens maintained under normal cycles (15.25 h light/d) or continuous light. the lighting conditions had no effect on plasma concentrations of lh before and at the pre-ovulatory lh peak in first, mid-s ... | 1987 | 3567681 |
| comparisons of time intervals and plasma lh concentrations during the ovulatory cycle of broiler breeder hens maintained under either a 24 h light:dark cycle or continuous light. | the possibility that egg production in broiler breeder hens may be increased by selection for reduced oviposition interval under continuous light was investigated by comparing the pattern of pre-ovulatory releases of plasma luteinising hormone (lh) and the associated ovipositions in the same broiler hens maintained under normal cycles (15.25 h light/d) or continuous light. the lighting conditions had no effect on plasma concentrations of lh before and at the pre-ovulatory lh peak in first, mid-s ... | 1987 | 3567681 |
| the hemodynamic effects of sympathetic stimulation combined with parasympathetic blockade in man. | to define the effects of circulating norepinephrine and epinephrine on cardiac function and to determine whether left ventricular function is influenced by parasympathetic mechanisms during catecholamine stimulation, hemodynamic changes were investigated in healthy young human subjects who were supine and awake during infusion of intravenous norepinephrine alone (125 ng/kg/min) (n = 6), norepinephrine (125 ng/kg/min) plus epinephrine (50 ng/kg/min) (n = 6), and norepinephrine plus epinephrine pl ... | 1987 | 3568309 |
| the end-systolic pressure-volume relationship in conscious dogs. | the end-systolic pressure-volume relationship (espvr) has been shown to be an afterload-insensitive descriptor of ventricular inotropic state in the isolated heart. the purpose of this study was to examine the effects of changes in afterload, heart rate, intravascular volume, autonomic tone, and inotropic state on the espvr in conscious dogs. in 30 dogs, left ventricular and pleural pressures were measured with micromanometers, and left ventricular volume was assessed with global ultrasonic crys ... | 1987 | 3568332 |