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agronomic viability of new zealand spinach and kale intercropping.the intercropping is a production system that aims to provide increased yield with less environmental impact, due to greater efficiency in the use of natural resources and inputs involved in the production process. an experiment was carried out to evaluate the agronomic viability of kale and new zealand spinach intercropping as a function of the spinach transplanting time. (0, 14, 28, 42, 56, 70, 84 and 98 days after transplanting of the kale). the total yield (ty) and yield per harvest (yh) of ...201828876391
the influence of non-steroidal anti-inflammatory drugs and paracetamol used for pain control of orthodontic tooth movement: a systematic review.the present study aimed to perform a systematic literature review to determine if there is a non-steroidal anti-inflammatory drug (nsaid) that interferes less within tooth movement. this research was performed according to the prisma statement. articles were searched in eight electronic databases (pubmed, scopus, embase, web of science, lilacs, scielo, google scholar, and open grey). only experimental studies on male wistar rats were selected, which included experiments related to the influence ...201828876390
phosphate solubilization by endophytic bacteria isolated from banana trees.forty isolates of endophytic bacteria isolated from banana tree roots were assessed as to their capacity to solubilize phosphate in a solid culture medium supplemented with different inorganic and one organic source of phosphorus. the amount of phosphorus (p) in each liquid medium was quantified, and an indirect assessment of acid phosphatase activity was performed. all assays had a fully randomized design, with three repetitions. approximately 67.5% of the 40 isolates assessed in solid medium s ...201828876357
inheritance of virulence, construction of a linkage map, and mapping dominant virulence genes in puccinia striiformis f. sp. tritici through characterization of a sexual population with genotyping-by-sequencing.puccinia striiformis f. sp. tritici, the wheat stripe rust pathogen, is a dikaryotic, biotrophic, and macrocyclic fungus. genetic study of p. striiformis f. sp. tritici virulence was not possible until the recent discovery of berberis spp. and mahonia spp. as alternate hosts. to determine inheritance of virulence and map virulence genes, a segregating population of 119 isolates was developed by self-fertilizing p. striiformis f. sp. tritici isolate 08-220 (race pstv-11) on barberry leaves under ...201828876207
a search for microorganisms producing medium-chain alkanes from aldehydes.microorganisms with medium-chain alkane-producing activity are promising for the bio-production of drop-in fuel. in this study, we screened for microorganisms producing tridecane from tetradecanal. the activity of aldehyde decarbonylation was found in a wide range of microbes. in particular, the genus klebsiella in the enterobacteriaceae family was found to have a high ability to produce alkanes from aldehydes via enzyme catalyzed reaction.201828869193
basidiospores attach to the seed of shorea leprosula in lowland tropical dipterocarp forest and form functional ectomycorrhiza on seed germination.this research aimed to study the ectomycorrhiza formed by basidiospores attached to the outer surface of shorea leprosula (dipterocarpaceae) seed collected from a lowland tropical dipterocarp forest. two groups of seeds were collected: control seeds collected from plastic net hanging 2 m above the ground and forest floor seeds collected on the forest floor. before planting, 15 seeds from each group were observed for basidiospores attached to the seed. ten of the 3-week-old s. leprosula seedlings ...201828866744
a biosocial cognitive model of cannabis use in emerging adulthood.the aim of this study was to test a new theoretical model of cannabis use incorporating biologically-based personality traits and social cognition. this biosocial cognitive theory (bsct) has robust support in alcohol studies, but has not been applied to cannabis. the model proposes two pathways linking dimensions of impulsivity to cannabis use. the first predicts that the association between reward sensitivity (sr) and cannabis use is mediated by positive outcome expectancies. the second predict ...201828863315
large-scale projects in the amazon and human exposure to mercury: the case-study of the tucuruí dam.the tucuruí dam is one of the largest dams ever built in the amazon. the area is not highly influenced by gold mining as a source of mercury contamination. still, we recently noted that one of the most consumed fishes (cichla sp.) is possibly contaminated with methylmercury. therefore, this work evaluated the mercury content in the human population living near the tucuruí dam. strict exclusion/inclusion criteria were applied for the selection of participants avoiding those with altered hepatic a ...201828858702
erratum to: comparison between inflammation-related markers in peri-implant crevicular fluid and clinical parameters during osseointegration in edentulous jaws. 201828868571
role of substance p and its receptor neurokinin 1 in chronic prurigo: a randomized, proof-of-concept, controlled trial with topical aprepitant.substance p (sp) and its receptor neurokinin 1 (nk1r) are thought to be involved in the pathogenesis of chronic prurigo. here, we assessed sp serum levels, cutaneous nk1r expression, and the effects of topical aprepitant, an nk1r antagonist, in patients with chronic prurigo. sp and nk1r were increased, compared with controls, in the serum and in lesional vs. non-lesional skin of the patients, respectively. aprepitant, in a randomized, placebo-controlled, split-sided, doubleblind trial, reduced t ...201828853492
double-stranded rna-mediated suppression of trypsin-like serine protease (t-sp) triggers over-expression of another t-sp isoform in helicoverpa armigera.high diversity of digestive proteases is considered to be the key factor in the evolution of polyphagy in helicoverpa armigera. serine proteases (sps) contribute ~85% of the dietary protein digestion in h. armigera. we investigated the dynamics of sp regulation in the polyphagous pest, h. armigera using rna interference (rnai). hatry1, an isoform of sp, expressed irrespective of the composition of the diet, and its expression levels were directly proportional to the larval growth rate. therefore ...201828852972
neuropsychological functioning in mid-life treatment-seeking adults with obesity: a cross-sectional study.the aim of this study is to compare cognitive functioning between treatment-seeking individuals with obesity and healthy-weight adults.201828849437
applying a food processing-based classification system to a food guide: a qualitative analysis of the brazilian experience.the present paper aimed to identify the stakeholders, as well as their arguments and recommendations, in the debate on the application of a food processing-based classification system to the new brazilian food guide.201828847335
mandibular implant-retained overdenture relining procedure with an attachment system: a step-by-step demonstration of the technique.because of continuous alveolar bone resorption, implant-retained overdentures need to be relined. the purpose of this study was to describe a method for relining an implant-retained overdenture.201828843500
changes in hdl-c concentrations after 16 weeks of combined training in postmenopausal women: characteristics of positive and negative responders.this study aimed to investigate the individual characteristics of body composition and metabolic profile that could explain interindividual variation in high-density lipoprotein cholesterol (hdl-c) concentrations in response to 16 weeks of combined strength plus aerobic (combined) training in postmenopausal women. the participants were divided into tertiles based on percentage of changes in hdl-c concentrations after combined training. only women in the upper tertile (positive responders: δ > 10 ...201828841397
gas effect on the emission and detection of the backscattered electrons in a vp-sem at low energy.the effect of the electron beam skirting on the emission and detection of the backscattered electrons (bse) in a low vacuum scanning electron microscope is investigated at low energy regime. monte carlo computed dependencies of the bse distribution on the water vapor and air pressure shown a significant increase of the extent of the bse exit zone. the pressure variation has however a little effect when helium gas is used. a new approach based on the comparison between the sizes of the skirt and ...201828837892
formation of olefins by eliminative dimerization and eliminative cross-coupling of carbenoids: a stereochemical exercise.two carbenoids combine to generate an olefin by a mechanism involving formation of an ate complex, 1,2-metalate rearrangement, and β-elimination. as each stage of this eliminative coupling is stereospecific, the overall stereochemical outcome can be understood and, in principle fully controlled, providing that the absolute stereochemical configurations of the reacting carbenoid species are defined. in contrast to traditional alkene syntheses, the eliminative cross-coupling of carbenoids offers a ...201828834041
relationship between total and segmental bone mineral density and different domains of physical activity among children and adolescents: cross-sectional study.this study aimed to investigate the relationship between total and segmental bone mineral density (bdm) and physical activity (pa) in different domains (school, leisure and sports) among adolescents and children.201828832809
metabolism studies of chiral pesticides: a critical review.the consumption of pesticides worldwide has been growing in recent decades, and consequently the exposure of humans and other animals to them as well. however, even though it is known that chiral pesticides can behave stereoselectively, the knowledge about the risks to human health and the environment is scarce. among the pesticides registered to date, approximately 30% have at least one center of asymmetry, and just 7% of them are currently marketed as a pure stereoisomer or as an enriched mixt ...201828844369
biodegradation of atrazine by the novel citricoccus sp. strain tt3.a previously undescribed atrazine-degrading bacterial strain tt3 capable of growing with atrazine as its sole nitrogen source was isolated from soil at the wastewater outfall of a pesticide factory in china. phenotypic characterization and 16s rrna gene sequencing indicated that the isolate belonged to the genus citricoccus. polymerase chain reaction (pcr) analysis revealed that tt3 contained the atrazine-degrading genes trzn, atzb, and atzc. the range for growth and atrazine degradation of tt3 ...201828841530
hexavalent chromium reduction potential of cellulosimicrobium sp. isolated from common effluent treatment plant of tannery industries.present study deals with the isolation and characterization of a bacterium capable for the effective reduction of cr(vi) from tannery wastewater. based on the 16s rrna gene sequence analysis, this bacterium was identified as cellulosimicrobium sp. (kx710177). during the cr(vi) reduction experiment performed at 50, 100, 200,and 300mg/l of cr(vi) concentrations, the bacterium showed 99.33% and 96.98% reduction at 50 and 100mg/l at 24 and 96h, respectively. however, at 200 and 300mg/l concentration ...201828841524
angelica lactones: from biomass-derived platform chemicals to value-added products.the upgrading of biomass-derived compounds has arisen in recent years as a very promising research field in both academia and industry. in this sense, a lot of new processes and products have been developed, often involving levulinic acid as a starting material or intermediate. in the last few years, though, other scaffolds have been receiving growing attention, especially, angelica lactones. considering these facts and the emergent applications of said molecules, in this review we will discuss ...201828834397
palisadegrass effects on n fertilizer dynamic in intercropping systems with corn.corn grain yield, nitrogen (n) fertilizer efficiency and distribution to corn alone and three forms of corn and palisadegrass (urochloa spp.) intercropping implantation was investigated. a field experiment with 15n labeling fertilizer was performed in randomized block design. no form of palisadegrass intercropping implantation affected corn grain yield, total n accumulation and n use efficiency (nue), which were 8.7 t ha-1, 205 kg ha-1 and 37% respectively. the palisadegrass produced on average ...201828832722
spider species richness and sampling effort at cracraft´s belém area of endemism.a list of spider species is presented for the belém area of endemism, the most threatened region in the amazon basin, comprising portions of eastern state of pará and western state of maranhão, brazil. the data are based both on records from the taxonomic and biodiversity survey literature and on scientific collection databases. a total of 319 identified species were recorded, with 318 occurring in pará and only 22 in maranhão. about 80% of species are recorded at the vicinities of the city of b ...201828832719
distinct taxonomic and functional composition of soil microbiomes along the gradient forest-restinga-mangrove in southeastern brazil.soil microorganisms play crucial roles in ecosystem functioning, and the central goal in microbial ecology studies is to elucidate which factors shape community structure. a better understanding of the relationship between microbial diversity, functions and environmental parameters would increase our ability to set conservation priorities. here, the bacterial and archaeal community structure in atlantic forest, restinga and mangrove soils was described and compared based on shotgun metagenomics. ...201828831604
halobium salinum sp. nov., isolated from a marine solar saltern.a halophilic archaeal strain yj-8-st was isolated from yangjiang marine solar saltern, china. cells from strain yj-8-st were pleomorphic, lysed in distilled water, stained gram-negative, and formed red-pigmented colonies on agar plate. optimal growth of the strain was obtained at 3.1 m nacl (range 1.4-4.8 m), 0.1 m mgcl2 (range 0.005-1.0 m), 37 °c (range 20-50 °c), and ph 7.5 (range 5.5-9.5). the major polar lipids are phosphatidylglycerol (pg), phosphatidylglycerol phosphate methyl ester (pgp-m ...201828831549
ozone affects leaf physiology and causes injury to foliage of native tree species from the tropical atlantic forest of southern brazil.in southern brazil, the recent increase in tropospheric ozone (o3) concentrations poses an additional threat to the biodiverse but endangered and fragmented remnants of the atlantic forest. given the mostly unknown sensitivity of tropical species to oxidative stress, the principal objective of this study was to determine whether the current o3 levels in the metropolitan region of campinas (mrc), downwind of são paulo, affect the native vegetation of forest remnants. foliar responses to o3 of thr ...201828830051
18f-fdg pet/ct in solitary plasmacytoma: metabolic behavior and progression to multiple myeloma.solitary plasmacytoma (sp) is a rare plasma-cell neoplasm, which can develop both in skeletal and/or soft tissue and frequently progresses to multiple myeloma (mm). our aim was to study the metabolic behavior of sp and the role of 18f-fdg-pet/ct in predicting progression to mm.201828822997
horizontal gaze palsy and progressive scoliosis: magnetic resonance imaging features and surgical treatment. 201828832711
temporal assessment of microbial communities in soils of two contrasting mangroves.variations in microbial communities promoted by alterations in environmental conditions are reflected in similarities/differences both at taxonomic and functional levels. here we used a natural gradient within mangroves from seashore to upland, to contrast the natural variability in bacteria, cyanobacteria and diazotroph assemblages in a pristine area compared to an oil polluted area along a timespan of three years, based on arisa (bacteria and cyanobacteria) and nifh t-rflp (diazotrophs) finger ...201828827029
advantages of single-port laparoscopic myomectomy compared with conventional laparoscopic myomectomy: a randomized controlled study.to compare operative outcomes of single-port laparoscopic myomectomy (sp-lm) vs conventional laparoscopic myomectomy (clm), including subjective and objective cosmetic aspects.201828826957
new nucleoside hydrolase with transribosylation activity from agromyces sp. mm-1 and its application for enzymatic synthesis of 2'-o-methylribonucleosides.microorganisms were screened for transribosylation activity between 2'-o-methyluridine (2'-ome-ur) and nucleobases, for the purpose of developing a biotransformation process to synthesize 2'-o-methylribonucleosides (2'-ome-nrs), which are raw materials for nucleic acid drugs. an actinomycete, agromyces sp. mm-1 was found to produce 2'-o-methyladenosine (2'-ome-ar) when whole cells were used in a reaction mixture containing 2'-ome-ur and adenine. the enzyme responsible for the transribosylation w ...201828826816
phytoactinopolyspora halotolerans sp. nov., a halotolerant actinobacterium isolated from a saline soil in xinjiang, northwest of china.a novel aerobic, gram-positive, non-motile halotolerant actinobacterium, designated strain yim 96448t, was isolated from a saline soil sample collected from the south bank of aiding lake in xinjiang province, northwest china. phylogenetic analysis based on 16s rrna gene sequences revealed that strain yim 96448t is closely related to phytoactinopolyspora endophytica egi 60009t (98.0%) and phytoactinopolyspora alkaliphila egi 80629t (97.0%). optimum growth of the strain was observed at 28-37 °c, p ...201828825140
high pressure studies on bis(l-histidinate)nickel(ii) monohydrate.raman spectra of bis(l-histidinate)nickel(ii) monohydrate crystal were obtained for pressures up to 9.5gpa. our results show the disappearance of some of the raman modes and the appearance of other modes. these modifications evidence that the sample undergoes phase transitions at around 0.8 and 3.2gpa. the role played by the ni ions and hydrogen bonds in the dynamics of the phase transitions is discussed. under decompression, down to atmospheric pressure, the original raman spectra are recovered ...201828823966
sex differences in cardiovascular, neuroendocrine and behavioral changes evoked by chronic stressors in rats.this study investigated the physiological, somatic and behavioral changes evoked by daily exposure to the same type of stressor (homotypic) or different aversive stressor stimuli (heterotypic) in male and female rats. for this, adult wistar rats were subjected to a 10days regimen of repeated restraint stress (rrs, homotypic stressor) or chronic variable stress (cvs, heterotypic stressor). effects evoked by cvs included: (i) adrenal hypertrophy and decreased body weight gain in male animals, (ii) ...201828823849
usefulness of the lymphocyte positional parameters in the sysmex xn haematology analyser in lymphoproliferative disorders and mononucleosis syndrome.the lymphocyte positional parameters included in sysmex xn have been suggested as useful means to differentiate lymphoproliferative disorders (lpd), mononucleosis syndrome (mns) and other lymphocytoses.201828868635
ovarian cancer stem cells promote tumour immune privilege and invasion via ccl5 and regulatory t cells.emerging evidence indicates a link between the increased proportion of regulatory t cells (tregs ) and reduced survival in patients who have been diagnosed with cancer. cancer stem cells (cscs) have been indicated to play a vital role in tumour initiation, drug resistance and recurrence. however, the relationship between tregs and cscs remains largely unknown. here, we sorted out ovarian cancer stem-like side population (sp) cells and cd133+ cells to investigate the influence of ovarian cscs on ...201828868628
methods for population-adjusted indirect comparisons in health technology appraisal.standard methods for indirect comparisons and network meta-analysis are based on aggregate data, with the key assumption that there is no difference between the trials in the distribution of effect-modifying variables. methods which relax this assumption are becoming increasingly common for submissions to reimbursement agencies, such as the national institute for health and care excellence (nice). these methods use individual patient data from a subset of trials to form population-adjusted indir ...201828823204
partial inferior turbinectomy in rhinoseptoplasty has no effect in quality-of-life outcomes: a randomized clinical trial.evaluate the impact of endoscopic partial inferior turbinectomy (epit) associated with primary rhinoseptoplasty on quality-of-life outcomes (qol), complications, and surgical duration.201828815717
evaluation of cell proliferation and endometrial thickness of bitches in different periods of diestrus.this study aimed to determine the histological features of the endometrium of bitches, as well as the cell proliferation at specific moments of diestrus, 10, 20, 30, 40, 50 and 60 days post ovulation, correlating the endometrial thickness with the uterine cell proliferation and the metabolic state (weight, blood glucose and plasma cholesterol) of the animals. therefore, the right and left uterine horns of 26 clinically healthy bitches submitted to ovariohysterectomy were histologically analyzed ...201828813095
efficacy and safety of using premedication with simethicone/pronase during upper gastrointestinal endoscopy examination with sedation: a single center, prospective, single blinded, randomized controlled trial.to investigate the efficacy and safety of premedication with simethicone/pronase during esophagogastroduodenoscopy (egd) with sedation.201828816373
a scientific survey on 1550 cases of oral lesions diagnosed in a brazilian referral center.the present study aimed to perform an epidemiological survey on the prevalence rate of oral lesions diagnosed in a referral center in brazil and to establish association between the lesions and the age and gender of the affected patients. this analytical observational study analyzed 3521 medical records of anatomopathological exams of the pathological anatomy and cytopathology laboratory of the cancer hospital of the state of mato grosso (brazil), from december 2011 to september 2015. a total of ...201828813105
terpene esters from natural products: synthesis and evaluation of cytotoxic activity.natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities against tumor cells. the derivatives were evaluated against five tumor cell lines [ovcar-8 (ovarian carcinoma); sf-295 (glioblastoma); hct-116 (colon adenocarcinoma); hl-60 (leukemia); and pc-3 (prostate carcinoma)] and the results showed only betulinic acid ...201828813102
leaf area estimation of cassava from linear dimensions.the objective of this study was to determine predictor models of leaf area of ​​cassava from linear leaf measurements. the experiment was carried out in greenhouse in the municipality of botucatu, são paulo state, brazil. the stem cuttings with 5-7 nodes of the cultivar iac 576-70 were planted in boxes filled with about 320 liters of soil, keeping soil moisture at field capacity, monitored by puncturing tensiometers. at 80 days after planting, 140 leaves were randomly collected from the top, mid ...201828813099
glucagon-like peptides 1 and 2 are involved in satiety modulation after modified biliopancreatic diversion: results of a pilot study.this paper aimed to evaluate the influence of modified biliopancreatic diversion (bpd) on the levels of glp-1 and glp-2 and correlate them with satiety regulation.201828808865
assessing the measurement invariance of the brief multidimensional students' life satisfaction scale in chinese and american adolescents.this study evaluated the measurement invariance of the brief multidimensional students' life satisfaction scale (bmslss) and latent means across early adolescents from two diverse cultural settings, china and america.201828808851
characterization of fm2382 from fulvimarina manganoxydans sp. nov. 8047 with potential enzymatic decontamination of sulfur mustard.sulfur mustard (sm) can be hydrolyzed by haloalkane dehalogenases such as dhaa, linb and dmba. however, the low resistance to the elevated temperatures limited the practical application of haloalkane dehalogenases. here we reported a new thermotolerant dehalogenase fm2382 from fulvimarina manganoxydans sp. nov. 8047. the specific activity of fm2382 to sm is 0.6 u/mg. fm2382 possessed high heat stability (45 °c) in slight alkali environment (ph 7.5) and retained approximately 50% activity after i ...201828807839
synergistic effect of quercetin and ph-responsive deae-chitosan carriers as drug delivery system for breast cancer treatment.amphiphilic chitosans, which may self-assemble in aqueous solution to form nanoaggregates with different conformations depending to the environmental ph, can be used as drug transport and delivery agents, when the target ph differs from the delivery medium ph. in this study, quercetin, a bioactive flavonoid, was encapsulated in a ph-responsive system based on amphiphilic chitosan. the hydrophilic reagent 2-chloro-n,n-diethylethylamine hydrochloride (deae), also known to inhibit the proliferation ...201828807690
early regression of carotid intima-media thickness after bariatric surgery and its relation to serum leptin reduction.bariatric surgery (bs) promotes carotid intima-media thickness (c-imt) regression as early as 6 months post-surgery. to verify whether c-imt regression occurs even earlier, we aimed at the effect of roux-en-y gastric bypass (rygbp) and biliopancreatic diversion (bpd) on c-imt 1-2 months and 12 months post-surgery.201828803396
corrigendum to "salivary levels of nickel, chromium, iron, and copper in patients treated with metal or esthetic fixed orthodontic appliances: a retrospective cohort study" [j. trace elem. med. biol. 40 (2017) 67-71]. 201828801010
the stress-induced scp/hlip family of small light-harvesting-like proteins (scpabcde) protects photosystem ii from photoinhibitory damages in the cyanobacterium synechocystis sp. pcc 6803.small cab-like proteins (scps) are single-helix light-harvesting-like proteins found in all organisms performing oxygenic photosynthesis. we investigated the effect of growth in moderate salt stress on these stress-induced proteins in the cyanobacterium synechocystis sp. pcc 6803 depleted of photosystem i (psi), which expresses scps constitutively, and compared these cells with a psi-less/scpabcde- mutant. scps, by stabilizing chlorophyll-binding proteins and photosystem ii (psii) assembly, prot ...201828795265
a cr(vi) selective probe based on a quinoline-amide calix[4]arene.a new quinoline-amide calix[4]arene 3-receptor for detection of hazardous anions and cations have been synthesized. the 3-receptor was examined for its sensing properties towards several different anions (cr2o72-, scn-, f-, cl-, no3-) and metal ions (hg2+, cd2+, ag+) by uv-vis and fluorescence spectroscopies. it was detected that the 3-receptor has only sensing ability for cr2o72- and hg2+ ions, resulting in the association constants higher for cr2o72- than to the hg2+ ions. high selectivity tow ...201828797841
cone beam computed tomography-based cephalometric norms for brazilian adults.this study established cone beam computed tomography (cbct)-based cephalometric norms for brazilian adults, including the assessment of sexual dimorphism. an observer performed mcnamara's cephalometric analysis twice on 60 cbct datasets acquired from patients with a normal dental occlusion, divided equally into two groups by sex. welch's t-test was applied to assess differences between the sexes in hard tissue cephalometric measurements, and dahlberg's formula was used to calculate measurement e ...201828803737
improved biotransformation of arsenic by arsenite oxidase - chitosan nanoparticle conjugates.recent developments in the potential use of nanoparticles as carriers of enzyme have attracted great attention. in the present study, arsenite oxidase (aoase) enzyme capable of transforming the more toxic arsenite [as(iii)] to the less toxic arsenate [as(v)] was extracted from an arsenic resistant bacterium (exiguobacterium sp. as-9) and partially purified. chitosan nanoparticles were prepared on the basis of ionic gelation of chitosan with tripolyphosphate (tpp) anions. the purified aoase was i ...201828803973
global-scale patterns of nutrient density and partitioning in forests in relation to climate.knowledge of nutrient storage and partitioning in forests is imperative for ecosystem models and ecological theory. whether the nutrients (n, p, k, ca, and mg) stored in forest biomass and their partitioning patterns vary systematically across climatic gradients remains unknown. here, we explored the global-scale patterns of nutrient density and partitioning using a newly compiled dataset including 372 forest stands. we found that temperature and precipitation were key factors driving the nutrie ...201828796923
indirect costs of diabetes and its impact on the public finance: the case of poland.growing public and private expenditure on healthcare results i.a. from the spreading of chronic diseases. diabetes belongs to the most frequent ones, beyond neoplasms and cardiological diseases, and hence generates a significant burden for the public finance in terms of the direct costs. however, the economy suffers also from the indirect cost of diabetes that manifests itself in the loss in gross domestic product (gdp) and general government revenues.201828796563
geo-environmental zoning using physiographic compartmentalization: a proposal for supporting sustainable decision-making.the geo-environmental zoning represents an important strategy in the territorial management. however, it requires a logical and structured procedure. therefore, an approach using physiographic compartmentalization is proposed and applied as case study in a region covered by the topographic maps of são josé dos campos and jacareí, brazil. this region has great geological and geomorphological peculiarities, beyond being a place with large human interventions because of its quickly economic growth. ...201828793008
editorial comment: use of indocyanine green angiography in microsurgical subinguinal varicocelectomy - lessons learned from our initial experience. 201828792187
scopuquinolone b, a new monoterpenoid dihydroquinolin-2(1h)-one isolated from the coral-derived scopulariopsis sp. fungus.further chemical investigation of the secondary metabolites of the fungus scopulariopsis sp. led to the discovery of a new alkaloid, scopuquinolone b (1). the structure of compound 1 was elucidated by extensive nmr spectroscopic data, cd spectrum and analysis of its dess-martin oxidation derivative. compound 1 was evaluated for antilarval settlement activity of barnacle balanus amphitrite and showed promising antifouling activity with an ec50 value of 0.103 μm and a high therapeutic ratio of 222 ...201828783962
comparison of single-port and conventional laparoscopic abdominoperineal resection.within the last two decades, surgical treatment of colorectal cancer has changed dramatically from large abdominal incisions to minimal access surgery. in the recent years, single port (sp) surgery has spawned from conventional laparoscopic surgery. the purpose of this study was to compare conventional with sp laparoscopic abdominoperineal resection (lapr) for rectal cancer.201828782746
impact of the removal of n-terminal non-structured amino acids on activity and stability of xylanases from orpinomyces sp. pc-2.xylanases catalyze the random hydrolysis of xylan backbone from plant biomass and thus, they have application in the production of biofuels, kraft pulps biobleaching and feed industry. here, xylanases derived from orpinomyces sp. pc-2 were engineered guided by molecular dynamics methods to obtain more thermostable enzymes. based on these models, 27 amino acid residues from the n-terminal were predicted to reduce protein stability and the impact of this removal was validated to two enzyme constru ...201828782612
markers of nutritional status and mortality in older adults: the role of anemia and hypoalbuminemia.the aim of the present study was to analyze the impact of anemia and hypoalbuminemia on mortality in a 5-year period.201828782162
new asymmetrical bispyrrolidinoindoline diketopiperazines from the marine fungus aspergillus sp. dx4h.known diketopiperazine win 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus aspergillus sp. dx4h. the planar and stereochemistry for new compounds were determined by a suite of techniques including mass, nmr and cd spectra together with marfey's method. their inhibitory activity against pc3 cell line had been tested.201828786310
ru(ii)/diphenylphosphine/pyridine-6-thiolate complexes induce s-180 cell apoptosis through intrinsic mitochondrial pathway involving inhibition of bcl-2 and p53/bax activation.the aim of this work was the synthesis, characterization, and cytotoxicity evaluation of three new ru(ii) complexes with a general formula [ru(spy)(bipy)(p-p)]pf6 [spy = pyridine-6-thiolate; bipy = 2,2'-bipyridine; p-p = 1,2-bis(diphenylphosphine)ethane (1); 1,3-bis(diphenylphosphine) propane (2); and 1,1'-bis(diphenylphosphino)ferrocene] (4). complex (3) with the 1,4-bis(diphenylphosphine)butane ligand, already known from the literature, was also synthesized, to be better studied here. the cyto ...201828795366
prevalence of suicidal behaviors in patients with major depressive disorder in china: a comprehensive meta-analysis.suicidal behaviors are common in major depressive disorder (mdd) and contribute significantly to premature death. the objective of this meta-analysis is to estimate the pooled prevalence of suicidal behaviors in patients with mdd in china.201828779680
determination of b-complex vitamins in pharmaceutical formulations by surface-enhanced raman spectroscopy.the aim of this work was to quantify b-complex vitamins in pharmaceutical samples by surface enhanced raman spectroscopy technique using gold colloid substrate. synthesis of gold nanoparticles was performed according to an adapted turkevich method. initial essays were able to suggest the orientation of molecules on gold nanoparticles surface. central composite design was performed to obtain the highest sers signal for nicotinamide and riboflavin. the evaluated parameters in the experimental desi ...201828779620
high-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells.endothelial cells (ecs) play a major role in blood vessel formation and function. while there is longstanding evidence for the potential of chemical exposures to adversely affect ec function and vascular development, the hazard potential of chemicals with respect to vascular effects is not routinely evaluated in safety assessments. induced pluripotent stem cell (ipsc)-derived ecs promise to provide a physiologically relevant, organotypic culture model that is amenable for high-throughput (ht) ec ...201828771372
electrodermal responses to discrete stimuli measured by skin conductance, skin potential, and skin susceptance.presently, electrodermal activity (eda) is the preferred term for changes in electrical properties of the skin. change in the skin conductance responses (scrs) and skin potential responses (sprs) due to external stimuli have previously been investigated in a number of studies, but very little for skin susceptance responses (ssrs) recorded simultaneously at the same skin site. this study aimed to investigate the association between the three parameters of eda, skin conductance (sc), skin potentia ...201828776764
support vector machine-based differentiation between aggressive and chronic periodontitis using microbial profiles.the existence of specific microbial profiles for different periodontal conditions is still a matter of debate. the aim of this study was to test the hypothesis that 40 bacterial species could be used to classify patients, utilising machine learning, into generalised chronic periodontitis (chp), generalised aggressive periodontitis (agp) and periodontal health (ph).201828771699
numerical simulations to assess art and mart performance for ionospheric tomography of chapman profiles.the incomplete geometrical coverage of the global navigation satellite system (gnss) makes the ionospheric tomographic system an ill-conditioned problem for ionospheric imaging. in order to detect the principal limitations of the ill-conditioned tomographic solutions, numerical simulations of the ionosphere are under constant investigation. in this paper, we show an investigation of the accuracy of algebraic reconstruction technique (art) and multiplicative art (mart) for performing tomographic ...201828767893
long-acting muscarinic antagonists vs. long-acting β 2 agonists in copd exacerbations: a systematic review and meta-analysis.to determine whether long-acting muscarinic antagonists (lamas) provide superior therapeutic effects over long-acting β2 agonists (labas) for preventing copd exacerbations.201828767773
effects of training and overtraining on intervertebral disc proteoglycans.animal experimental study.201828767620
a statistical review of alternative zinc and copper extraction from mineral fertilizers and industrial by-products.rapid, accurate, and low-cost alternative analytical methods for micronutrient quantification in fertilizers are fundamental in qc. the purpose of this study was to evaluate whether zinc (zn) and copper (cu) content in mineral fertilizers and industrial by-products determined by the alternative methods usepa 3051a, 10% hcl, and 10% h2so4 are statistically equivalent to the standard method, consisting of hot-plate digestion using concentrated hcl. the commercially marketed zn and cu sources in br ...201828766485
anaerobic digestion effluents (ades) treatment coupling with chlorella sp. microalgae production.nutrient removal effectiveness from anaerobic digestion effluents (ades) by chlorella sp. cultivation and microalgae biomass productivity were evaluated in this study. the results showed that the highest chlorella sp. biomass productivities of 386.5 ± 24.1 mg dry weight/l•d and 338.3 ± 11.0 mg dry weight/l•d were respectively obtained with the anaerobically digested effluent of municipal wastewater sludge and effluent from a fermentation tank treating dairy wastewater. lower (p < 0.05) microalga ...201828766484
natural acidification changes the timing and rate of succession, alters community structure, and increases homogeneity in marine biofouling communities.ocean acidification may have far-reaching consequences for marine community and ecosystem dynamics, but its full impacts remain poorly understood due to the difficulty of manipulating pco2 at the ecosystem level to mimic realistic fluctuations that occur on a number of different timescales. it is especially unclear how quickly communities at various stages of development respond to intermediate-scale pco2 change and, if high pco2 is relieved mid-succession, whether past acidification effects per ...201828762601
hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity.hypothalamic dysfunction is a common feature of experimental obesity. studies have identified at least three mechanisms involved in the development of hypothalamic neuronal defects in diet-induced obesity: i, inflammation; ii, endoplasmic reticulum stress; and iii, mitochondrial abnormalities. however, which of these mechanisms is activated earliest in response to the consumption of large portions of dietary fats is currently unknown. here, we used immunoblot, real-time pcr, mitochondrial respir ...201828760600
is food store type associated with the consumption of ultra-processed food and drink products in brazil?to analyse the association between food store type and the consumption of ultra-processed products in brazil.201828756782
fully disposable microfluidic electrochemical device for detection of estrogen receptor alpha breast cancer biomarker.a novel fully disposable microfluidic electrochemical array device (µfed) was developed and successfully applied for detection of the biomarker estrogen receptor alpha (erα). the µfed was constructed using low-cost materials and an inexpensive home cutter printer enabled the manufacture of dozens of µfeds in less than 2h, at a cost of less than us$ 0.20 in material per device. the µfed incorporates counter and reference electrodes and eight carbon-based working electrodes, which were modified wi ...201828755608
epileptic rat brain tissue analyzed by 2d correlation raman spectroscopy.absence epilepsy is the neurological disorder characterized by the pathological spike-and wave discharges present in the electroencephalogram, accompanying a sudden loss of consciousness. experiments were performed on brain slices obtained from young male wag/rij rats (2-3weeks old), so that they were sampled before the appearance of brain-damaging seizures symptoms. two differing brain areas of the rats' brain tissue were studied: the somatosensory cortex (sc) and the dorsal lateral geniculate ...201828772144
picosecond excitation energy transfer of allophycocyanin studied in solution and in crystals.cyanobacteria perform photosynthesis with the use of large light-harvesting antennae called phycobilisomes (pbss). these hemispherical pbss contain hundreds of open-chain tetrapyrrole chromophores bound to different peptides, providing an arrangement in which excitation energy is funnelled towards the pbs core from where it can be transferred to photosystem i and/or photosystem ii. in the pbs core, many allophycocyanin (apc) trimers are present, red-light-absorbing phycobiliproteins that covalen ...201828755150
adolescents' physical activity is associated with previous and current physical activity practice by their parents.the purpose of this study was to determine whether parents' current and previous physical activity practice is associated with adolescents' physical activity.201828754602
a novel lateral approach to the assessment of vocal cord movement by ultrasonography.ultrasonography is a non-invasive technique that is commonly used by endocrinologists and endocrine surgeons to examine the thyroid region and could be useful for the assessment of vocal cord movement by these specialists. however, previous studies reported a low rate of successful visualization of vocal cord movement by ultrasonography. to address this issue, we devised a novel ultrasonographic procedure for assessing vocal cord movement indirectly by observing the arytenoid movement from a lat ...201828752427
ferritin light chain gene mutations in two brazilian families with hereditary hyperferritinemia-cataract syndrome.hereditary hyperferritinemia-cataract syndrome is an autosomal dominant genetic disorder associated with mutations in the 5'utr region of the ferritin light chain gene. these mutations cause the ferritin levels to increase even in the absence of iron overload. patients also develop bilateral cataract early due to accumulation of ferritin in the lens, and many are misdiagnosed as having hemochromatosis and thus not properly treated. the first cases were described in 1995 and several mutations hav ...201828746593
cost analysis of substitutive renal therapies in children.end-stage renal disease is a health problem that consumes public and private resources. this study aimed to identify the cost of hemodialysis (either daily or conventional hemodialysis) and transplantation in children and adolescents.201828750890
telomerase enzyme deficiency promotes metabolic dysfunction in murine hepatocytes upon dietary stress.short telomeres and genetic telomerase defects are risk factors for some human liver diseases, ranging from non-alcoholic fatty liver disease and non-alcoholic steatohepatitis to cirrhosis. in murine models, telomere dysfunction has been shown to metabolically compromise hematopoietic cells, liver and heart via the activation of the p53-pgc axis.201828741793
barriers to and facilitators of ultra-processed food consumption: perceptions of brazilian adults.to explore how individuals perceive the availability of ultra-processed foods in their neighbourhoods and the barriers to and facilitators of consumption of such foods.201828738908
vibrational microspectroscopy analysis of human lenses.in this study we present vibrational analysis of healthy (non-affected by cataract) and cataractous human lenses by means of raman and ftir spectroscopy methods. the performed analysis provides complex information about the secondary structure of the proteins and conformational changes of the amino acid residues due to the formation of opacification of human lens. briefly, the changes in the conformation of the tyr and trp residues and the protein secondary structure between the healthy and cata ...201828746907
growth, meat and feed efficiency traits of lambs born to ewes submitted to energy restriction during mid-gestation.the objective of this study was to evaluate the effects of the energy restriction of gestation of adult ewes from day 45 to day 115 on lamb live performance parameters, carcass and meat traits. in experiment i, dietary energy was restricted at 70% of the metabolizable energy (me) requirements, after which ewes were re-fed ad libitum until lambing. in experiment ii, dietary energy was restricted at 60% of the me requirements, and ewes were re-fed to me requirements until lambing. all ewes grazed ...201828735589
changes in global transcriptional profiling of women following obesity surgery bypass.differential gene expression in peripheral blood mononuclear cells (pbmcs) after roux-en-y gastric bypass (rygb) is poorly characterized. markers of these processes may provide a deeper understanding of the mechanisms that underlie these events. the main goal of this study was to identify changes in pbmc gene expression in women with obesity before and 6 months after rygb-induced weight loss.201828735374
evaluation of noninvasive hemoglobin monitoring in trauma patients with low hemoglobin levels.bleeding is a leading cause of death among trauma patients. delayed assessment of blood hemoglobin level might result in either unnecessary blood transfusion in nonindicated patients or delayed blood transfusion in critically bleeding patients. in this study, we evaluate the precision of noninvasive hemoglobin monitoring in trauma patients with low hemoglobin levels.201828727608
boar sperm quality after supplementation of diets with omega-3 polyunsaturated fatty acids extracted from microalgae.this study evaluated effects of diet supplementation with omega-3 polyunsaturated fatty acids (pufa) from microalgae on boar sperm quality. two groups of boars (n = 3 each) were fed during 75 days either a commercial diet (control), or the same diet supplemented with omega-3 pufa from the heterotrophic microalgae schizochytrium sp. (120 g/kg). sixteen ejaculates were collected per boar. some sperm kinetics parameters were inferior for supplemented than for control boars (p < .05): distance avera ...201828730698
addressing the environment electrostatic effect on ballistic electron transport in large systems: a qm/mm-negf approach.the effects of the environment in nanoscopic materials can play a crucial role in device design. particularly in biosensors, where the system is usually embedded in a solution, water and ions have to be taken into consideration in atomistic simulations of electronic transport for a realistic description of the system. in this work, we present a methodology that combines quantum mechanics/molecular mechanics methods (qm/mm) with the nonequilibrium green's function framework to simulate the electr ...201828721724
the share of ultra-processed foods determines the overall nutritional quality of diets in brazil.to estimate the dietary share of ultra-processed foods and to determine its association with the overall nutritional quality of diets in brazil.201828714425
household availability of ultra-processed foods and obesity in nineteen european countries.to assess household availability of nova food groups in nineteen european countries and to analyse the association between availability of ultra-processed foods and prevalence of obesity.201828714422
metagenomic analysis of subtidal sediments from polar and subpolar coastal environments highlights the relevance of anaerobic hydrocarbon degradation processes.in this work, we analyzed the community structure and metabolic potential of sediment microbial communities in high-latitude coastal environments subjected to low to moderate levels of chronic pollution. subtidal sediments from four low-energy inlets located in polar and subpolar regions from both hemispheres were analyzed using large-scale 16s rrna gene and metagenomic sequencing. communities showed high diversity (shannon's index 6.8 to 10.2), with distinct phylogenetic structures (<40% shared ...201828702706
characterization of spac-type erysipelothrix sp. isolates causing systemic disease in ornamental fish.since 2012, low-to-moderate mortality associated with an erysipelothrix sp. bacterium has been reported in ornamental fish. histological findings have included facial cellulitis, necrotizing dermatitis and myositis, and disseminated coelomitis with abundant intralesional gram-positive bacterial colonies. sixteen erysipelothrix sp. isolates identified phenotypically as e. rhusiopathiae were recovered from diseased cyprinid and characid fish. similar clinical and histological changes were also obs ...201828708262
sponge prokaryote communities in taiwanese coral reef and shallow hydrothermal vent ecosystems.previously, it was believed that the prokaryote communities of typical 'low-microbial abundance' (lma) or 'non-symbiont harboring' sponges were merely subsets of the prokaryote plankton community. recent research has, however, shown that these sponges are dominated by particular clades of proteobacteria or cyanobacteria. here, we expand on this research and assess the composition and putative functional profiles of prokaryotic communities from lma sponges collected in two ecosystems (coral reef ...201828699015
validation of a model for predicting smear-positive active pulmonary tuberculosis in patients with initial acid-fast bacilli smear-negative sputum.the objective of this study was to develop a predictive model for final smear-positive (sp) active pulmonary tuberculosis (aptb) in patients with initial negative acid fast bacilli (afb) sputum smears (isn-sp-aptb) based on high-resolution computed tomography (hrct).201828710581
differential role of the anterior and intralaminar/lateral thalamic nuclei in systems consolidation and reconsolidation.the anterior thalamic nuclei (atn) and the intralaminar/lateral thalamic nuclei (iln/lt) play different roles in memory processes. the atn are believed to be part of an extended hippocampal system, and the iln/lt have strong connections with the medial prefrontal cortex. it was shown that the iln/lt are involved in systems consolidation. however, whether they are necessary for memory retrieval as well remains unclear. we, therefore, used c-fos immunohistochemistry and reversible inactivations to ...201828710525
15-deoxy-isoxeniolide-a, new diterpenoid from a bornean soft coral, xenia sp.a new xenicane diterpenoid, 15-deoxy-isoxeniolide-a (1) along with four known compounds 9-deoxy-isoxeniolide-a (2), isoxeniolide-a (3), xeniolide-a (4) and coraxeniolide-b (5) were isolated from the bornean soft coral xenia sp. the structures of these metabolites were elucidated on the basis of spectral analysis, nmr and hresims. compound 5 showed cytotoxic activity against atl cell line, s1t.201828691521
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