Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| metastatic factors for krukenberg tumor: a clinical study on 102 cases. | to investigate factors associated with gastrointestinal (gi) carcinomas metastasizing to ovaries to form krukenberg tumor. among the 102 cases of krukenberg tumor due to gi cancers, there were 41 cases synchronously diagnosed, 43 cases with primary tumor identified first and 18 cases with ovarian tumor identified first. metastatic factors of 43 cases of metachronous krukenberg tumor were analyzed with univariate and multivariate methods. of the 43 patients, the median age at diagnosis of krukenb ... | 2010 | 20607456 |
| urothelial carcinoma of the bladder with seminal vesicle invasion: prognostic significance. | to evaluate the prognostic impact of seminal vesicle invasion in men who underwent radical cystectomy for bladder cancer. | 2010 | 20608931 |
| molecular characterization and gene expression of thyrotropin-releasing hormone in senegalese sole (solea senegalensis). | we describe the cloning of a cdna encoding trh in solea senegalensis. phylogenetic analysis clustered it with other fish counterparts. eight conserved trh progenitors and highly divergent spacers were identified. expression profiles of trh were analyzed in juvenile tissues, during larval development, and in post-larvae grew under four photoperiods (12l:12d, 12d:12l, 24l:0d and 24d:0l) during four weeks using a real-time pcr approach. in juvenile fish, trh mrna was expressed ubiquitously although ... | 2010 | 20570750 |
| early-stage invasive breast cancers: potential role of optical tomography with us localization in assisting diagnosis. | to investigate the potential role of optical tomography in the near-infrared (nir) spectrum with ultrasonographic (us) localization as a means of differentiating early-stage cancers from benign lesions of the breast. | 2010 | 20571122 |
| supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting. | it has been shown that supplemental oxygen reduces the incidence of postoperative nausea and vomiting (ponv) in patients undergoing colon surgery. serotonin is a potent trigger of ponv. theoretically, supplemental oxygen decreases gut ischaemia during surgery and in this way minimizes the release of serotonin. we investigated the release of serotonin during and after colorectal surgery with normal and supplemental oxygen administration. | 2010 | 20613542 |
| effectiveness of neoadjuvant radiotherapy in the treatment of locally advanced rectal cancer: a single-center experience in 263 patients. | to determine the frequency of local recurrence (lr) and distant recurrence (dr) with 5-year survival analysis. | 2010 | 20571269 |
| the sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid photosensitizes the formation of oxidized guanines in cellulo after uv-a or uv-b exposure. | the sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid (pbsa) is water soluble and is widely used in the cosmetic industry because it absorbs strongly at uv-b wavelengths. previous studies have shown that pbsa, photoexcited by uv-b, oxidizes guanine bases in vitro. because of its potential phototoxic effect, it is important to determine whether pbsa photosensitizes in cellulo the formation of oxidatively generated dna damage on uv exposure. for this purpose, we investigated, in vitro and in c ... | 2010 | 20574440 |
| nasopharyngeal carcinoma: differences in presentation between different ethnicities in the new zealand setting. | there is an elevated incidence of nasopharyngeal carcinoma (npc) in the maori and pacific island (mpi) population as well as the asian population in new zealand; however, no studies have been conducted to evaluate how the two populations differ in their clinical presentation according to the tnm stage. | 2010 | 20575952 |
| postoperative residual curarization from intermediate-acting neuromuscular blocking agents delays recovery room discharge. | postoperative residual curarization (porc) [train-of-four ratio (t4/t1) <0.9] is associated with increased morbidity and may delay postoperative recovery room (pacu) discharge. we tested the hypothesis that postoperative t4/t1 <0.9 increases pacu length of stay. | 2010 | 20576632 |
| intestinal permeability enhancement of levothyroxine sodium by straight chain fatty acids studied in mdck epithelial cell line. | levothyroxine sodium (t4), administered orally, is used for the treatment of hypothyroidism. t4 is a narrow therapeutic index drug with highly variable bioavailability (40-80%). the purpose of the present study was to increase the transepithelial transport of t4 using straight chain fatty acids across madin-darby canine kidney (mdck) cell line. capric acid (c10), lauric acid (c12) and oleic acid (c18) were studied in molar ratios of 1:0.5, 1:1, 1:2 and 1:3 (t4:fatty acid). transport of the hydro ... | 2010 | 20580671 |
| floating tablet of trimetazidine dihydrochloride: an approach for extended release with zero-order kinetics. | trimetazidine dihydrochloride is an effective anti-anginal agent; however, it is freely soluble in water and suffers from a relatively short half-life. to solve this encumbrance, it is a prospective candidate for fabricating trimetazidine extended-release formulations. trimetazidine extended-release floating tablets were prepared using different hydrophilic matrix forming polymers including hpmc 4000 cps, carbopol 971p, polycarbophil, and guar gum. the tablets were fabricated by dry coating tech ... | 2010 | 20582493 |
| usefulness of endoscopic ultrasonography in preoperative gastric cancer staging: diagnostic yield and therapeutic impact. | to evaluate the diagnostic yield of endoscopic ultrasonography in loco-regional staging of gastric cancer in our medium and to determine the impact of this technique on later therapeutic management. | 2010 | 20617861 |
| exploration of potential prodrug approach of the bis-thiazolium salts t3 and t4 for orally delivered antimalarials. | we report here the synthesis and biological evaluation of a series of 37 compounds as precursors of potent antimalarial bis-thiazolium salts (t3 and t4). these prodrugs were either thioester, thiocarbonate or thiocarbamate type and were synthesized in one step by reaction of an alkaline solution of the parent drug with the appropriate activated acyl group. structural variations affecting physicochemical properties were made in order to improve oral activity. twenty-five of them exhibited potent ... | 2010 | 20605450 |
| [the role of the "heil- und pflegeanstalt" (state hospital) günzburg in the context of the "aktion-t4"]. | in the context of the national socialist "aktion-t4" approximately 70,000 people with mental illness and mental handicap in germany were killed. the "heil- und pflegeanstalt" (mental hospital) günzburg was a so-called bavarian "sammelanstalt" during this period. | 2010 | 20560117 |
| [sentinel lymph node biopsy in patients with melanoma]. | the incidence of melanoma is currently increasing worldwide. one of the factors influencing disease prognosis is the presence of regional lymph node metastases. sentinel lymph node biopsy attempts to identify subclinical lymph node metastasis as a prognostic factor in the disease. the aim of this study was to analyze differences between patients with melanoma for whom positive or negative results were obtained in sentinel lymph node biopsy and to assess the impact of the technique on disease pro ... | 2010 | 20525486 |
| identifying and reducing error in cluster-expansion approximations of protein energies. | protein design involves searching a vast space for sequences that are compatible with a defined structure. this can pose significant computational challenges. cluster expansion is a technique that can accelerate the evaluation of protein energies by generating a simple functional relationship between sequence and energy. the method consists of several steps. first, for a given protein structure, a training set of sequences with known energies is generated. next, this training set is used to expa ... | 2010 | 20602445 |
| epirubicin and docetaxel as neoadjuvant treatment of locally advanced breast cancer: a phase ii study. | neoadjuvant chemotherapy is the standard treatment for locally advanced breast cancer. the combination of anthracyclines and taxanes is considered the first choice chemotherapy in advanced breast cancer. we report here the overall results of a phase ii study of epirubicin and docetaxel as neoadjuvant chemotherapy in advanced breast cancer. | 2010 | 20572578 |
| clinical features of primary hyperthyroidism caused by graves' disease admixed with resistance to thyroid hormone (p453t). | a 34-year-old japanese woman was referred to the hospital because of general fatigue and palpitations. she was diagnosed as having resistance to thyroid hormone (rth) and hashimoto's thyroiditis at the age of 28. she felt general fatigue, palpitations, heat intolerance, and sweating for 6 months. thyroid function tests demonstrated elevated levels of free triidothyronine (t3) and free thyroxine (t4) that were above detectable ranges and a completely suppressed level of tsh that was below the det ... | 2010 | 20574139 |
| [significance of ipsilateral adrenalectomy in surgery for renal cell carcinoma]. | the aim of this study is to analyze the incidence of involvement of ipsilateral adrenal gland from renal cell carcinoma and assess the actual significance of ipsilateral adrenalectomy at nephrectomy. | 2010 | 20535986 |
| incremental effects of facemask therapy associated with intermaxillary mechanics. | to determine the dentofacial changes in children with skeletal class iii malocclusions treated with maxillary expansion, external maxillary protraction and intermaxillary traction. | 2010 | 20575205 |
| altered thyroid hormones and behavioural change in a sub-population of rats following chronic constriction injury. | hypothyroidism is associated with a disturbance of behaviour and mood. there are also individuals, not classified as hypothyroid, with low to 'low normal' thyroid hormone levels and normal thyroid-stimulating hormone (tsh) levels who have mood and behavioural changes. as the peripheral thyroid hormones decrease, tsh is expected to increase. however, there are a number of physiological mechanisms known to suppress tsh. in the present study, we report on thyroid hormone regulation in a rat model o ... | 2010 | 20553369 |
| brominated diphenyl ether (bde) levels in liver, adipose, and milk from adult and juvenile rats exposed by gavage to the de-71 technical mixture. | brominated diphenyl ethers (bdes) are used as flame retardants in consumer products. rodent studies indicate that the liver, thyroid, and nervous system of developing animals are targets of bdes. to explore the relationship between exposure and health in developing animals, bde accumulation in adult and juvenile rats was examined in conjunction with changes in liver weight and serum thyroxine (t4). adult (f0) rats received the commercial bde mixture de-71 by gavage at doses of 0.5, 5, and 25 mg ... | 2010 | 20549633 |
| treatment of cancer-related chest wall pain using spinal cord stimulation. | it has been estimated that 15% to 40% of chronic cancer pain has a neuropathic component, and this type of pain often responds poorly to opioids. in an attempt to provide increased pain relief for patients with intractable cancer pain, unconventional agents and interventional management approaches have received considerable attention. spinal cord stimulation (scs) has been used with increased frequency for the treatment of intractable cancer pain. | 2010 | 20555037 |
| platysma myocutaneous flap for oral cavity reconstruction. | a retrospective study was conducted to assess outcomes of reconstruction of the oral cavity with the platysma myocutaneous flap, in terms of flap survival, complications, and quality of life. included were 10 patients with squamous cell carcinoma (stage t1 to t4; nodal status n0 to n2) of the oral cavity who were treated between 2002 and 2006. each patient underwent tumor resection, modified radical neck dissection, and primary reconstruction with a platysma myocutaneous flap. operating time, le ... | 2010 | 20556740 |
| a comparison of the effect on qt interval between thiamylal and propofol during anaesthetic induction*. | summary: the aim of this study was to determine the effect of thiamylal and propofol on heart rate-corrected qt (qtc) interval during anaesthetic induction. we studied 50 patients undergoing lumbar spine surgery. patients were administered 3 microgxkg(-1) fentanyl and were randomly allocated to receive 5 mgxkg(-1) thiamylal or 1.5 mgxkg(-1) propofol as an induction agent. tracheal intubation was performed after vecuronium administration. heart rate, mean arterial pressure, bispectral index score ... | 2010 | 20528837 |
| the effects of stimulating lower leg muscles on the mechanical work and metabolic response in functional electrically stimulated pedaling. | functional electrical stimulation (fes) pedaling with the muscles of the upper leg has been shown to provide benefit to spinal cord injured (sci) individuals. fes pedaling with electrical stimulation timing patterns that minimize the stress-time integral of activated muscles has been shown to increase the work individuals can perform during the exercise compared to existing fes stimulation timing patterns. activation of the lower leg muscles could further enhance the benefit of fes pedaling by i ... | 2010 | 20529755 |
| [the beta-helical domain of bacteriophage t4 controls the folding of the fragment of long tail fibers in a chimeric protein]. | the key stage of the infection of the escherichia coli cell with bacteriophage t4, the binding to the surface of the host cell, is determined by the specificity of the long tail fiber proteins of the phage, in particular, gp37. the assembly and oligomerization of this protein under natural conditions requires the participation of at least two additional protein factors, gp57a and gp38, which strongly hinders the production of the recombinant form of gp37. to overcome this problem, a modern prote ... | 2010 | 20531477 |
| multifactorial, site-specific recurrence model after radical cystectomy for urothelial carcinoma. | a scoring algorithm of site-specific disease recurrence after cystectomy for urothelial carcinoma was designed. | 2010 | 20564121 |
| abcb1/mdr1 gene polymorphisms as a prognostic factor in colorectal cancer. | to analyse the single-nucleotide polymorphisms (snps): abcb1(1236c>t), abcb1(2677g>t/a), abcb1(3435c>t) and haplotypes in the abcb1/mdr1 gene, which could contribute to genetic risk of colorectal cancer (crc). disease association between the abcb1/mdr1 genotype, allele, haplotype frequencies and histological features, such as tnm classification, localization of primary carcinoma, grade of malignancy, histological type of tumour, lymphoid infiltration and vessel invasion were estimated. in this s ... | 2010 | 20533057 |
| chronic kidney disease-epidemiology formula and model for end-stage liver disease score in the assessment of renal function in candidates for liver transplantation. | assessment of renal function in patients with end-stage liver disease (esld) awaiting liver transplantation (olt) is critical. various conditions may cause renal damage in esld. renal and liver functions are intertwined due to splanchnic hemodynamic relationships; renal failure rarely occurs in patients without advanced decompensated cirrhosis. the recent literature suggests that evaluation of renal function should include an assessment of liver function. the aim of this study was to evaluate di ... | 2010 | 20534268 |
| factors associated with nonparticipation in one-year quality-of-life assessment in patients with head and neck squamous cell carcinoma. | to identify factors associated with nonparticipation in long-term quality-of-life (qol) analysis in head and neck squamous cell cancer (hnscc) patients. | 2010 | 20564472 |
| investigations of thyroid hormones and antibodies in obesity: leptin levels are associated with thyroid autoimmunity independent of bioanthropometric, hormonal, and weight-related determinants. | obesity can alter the thyroid hormone status as a result of a dysregulated endocrine loop between the hypothalamo-pituitary unit and adipose tissue. the adipocytokine leptin has been shown to promote autoimmunity; hence, we aimed to clarify whether leptin excess of obesity could increase the susceptibility to develop autoimmune thyroid disease (aitd). | 2010 | 20534769 |
| genetically engineered virulent phage banks in the detection and control of emergent pathogenic bacteria. | natural outbreaks of multidrug-resistant microorganisms can cause widespread devastation, and several can be used or engineered as agents of bioterrorism. from a biosecurity standpoint, the capacity to detect and then efficiently control, within hours, the spread and the potential pathological effects of an emergent outbreak, for which there may be no effective antibiotics or vaccines, become key challenges that must be met. we turned to phage engineering as a potentially highly flexible and eff ... | 2010 | 20569057 |
| overlap extension pcr cloning: a simple and reliable way to create recombinant plasmids. | here we describe a straightforward, efficient, and reliable way to clone an insert of choice into a plasmid of choice without restriction endonucleases or t4 dna ligase. chimeric primers containing plasmid sequence at the 5' ends and insert sequence at the 3' ends were used to pcr-amplify insertion sequences of various sizes, namely the genes for gfp (gfp), beta-d-glucuronidase (gusa), and beta-galactosidase (lacz), as well as the entire luxabcde operon. these inserts were employed as mega-prime ... | 2010 | 20569222 |
| highly sensitive detection of dna phosphorylation by counting single nanoparticles. | dna phosphorylation is a vital process in the repair, replication, and recombination of nucleic acids. traditionally, it is assayed by denaturing gel electrophoresis and autoradiography, which are tedious and not sensitive. we report on the development of a sensitive, simple, and economical method for dna phosphorylation detection and t4 polynucleotide kinase (t4 pnk) activity assay based on marking dna phosphorylation/biotinylation events by the attachment of fluorescent nanoparticles. enzyme a ... | 2010 | 20512316 |
| integrated positron emission tomography-computed tomography does not accurately stage intrathoracic disease of patients undergoing trimodality therapy for malignant pleural mesothelioma. | the results of trimodality therapy for malignant pleural mesothelioma (mpm) are related to stage. staging can be carried out by computed tomography (ct), magnetic resonance imaging and fluorodeoxyglucose positron emission tomography (fdg-pet), but all modalities suffer from limitations. we investigated whether integrated pet-ct improved the intrathoracic staging of patients undergoing trimodality therapy for mpm. | 2010 | 20514576 |
| effect of intrapleural povidone-iodine lavage on thyroid hormones in thoracic surgery. | povidone-iodine (pi) is an effective disinfectant used in many surgical operations. it is known that pi is absorbed by the skin after application. absorption is even greater in infants, as their skin is thinner and more permeable. iodine absorption in the orbita, neck and during abdominal surgery has been previously investigated, but such a study has not been performed for the pleura, which has a greater area and capacity for absorption. in this study, we investigated the effect of intraoperativ ... | 2010 | 20514578 |
| menstrual irregularity: a possible clinical marker of metabolic dysfunction in women with class iii obesity. | to evaluate whether menstrual irregularity in morbidly obese women is indicative of metabolic dysfunction. | 2010 | 20515256 |
| [spontaneous spinal subdural and epidural haematoma in a pregnant patient]. | we report a pregnant woman who developed non-traumatic spinal subdural and epidural hematoma. a 31-year-old woman at 28 weeks of gestation developed progressive ascending paralysis. mri suggested the presence of spinal subdural hematoma at t4-6 and spinal epidural hematoma at t4-9. an emergency cesarean section followed by spinal decompression was performed 60 hours after the onset. the patient's neulogical function recovered completely after the surgey. | 2010 | 20560387 |
| phase ii study of pre-operative radiotherapy with capecitabine and oxaliplatin for rectal cancer and carcinoembryonic antigen as a predictor of pathological tumour response. | this study investigated the efficacy and tolerability of pre-operative radiotherapy with concurrent capecitabine and oxaliplatin in patients with rectal cancer. forty-seven patients with rectal adenocarcinoma (stages t3 - t4; node-positive) were enrolled and received radiotherapy (46 gy in 23 fractions) in combination with capecitabine (1000 mg/m(2) twice daily on days 1 - 14 and 22 - 35) and oxaliplatin (130 mg/m(2) on days 1 and 22) (xelox regimen). the main endpoints were safety and efficacy, ... | 2010 | 20515578 |
| subclinical thyroid disease in elderly subjects. | subclinical thyroid disease (std) is defined as circulating concentrations of free t4 and free t3 within their respective reference ranges in the presence of abnormal circulating concentrations of tsh. scd is being diagnosed more frequently in clinical practice and is reported to be more prevalent in elderly as compared to young or adult subjects. the clinical impact of subclinical thyroid dysfunction is still a matter of debate, although it has been associated with various negative clinical out ... | 2010 | 20518189 |
| thyroid axis dysfunction in patients with prader-willi syndrome during the first 2 years of life. | prader-willi syndrome (pws) is a genetic disorder caused by the loss of expression of paternally transcribed genes in a highly imprinted region of chromosome 15q11-13. the clinical phenotype has been well characterized, mostly related to hypothalamic dysfunction. even though central hypothyroidism has been documented in 20-30% of patients with pws, thyroid function during the first 2 years of life has not been clearly defined. | 2010 | 20560980 |
| sacral neuromodulation in children with urinary and fecal incontinence: a multicenter, open label, randomized, crossover study. | the clinical benefit of sacral neuromodulation is unclear due to the paucity of randomized trial data. the purpose of this study was to evaluate sacral neuromodulation for management of urinary and fecal incontinence in a pediatric population. | 2010 | 20561645 |
| assessment of low-density lipoprotein oxidation, paraoxonase activity, and arterial distensibility in epileptic children who were treated with anti-epileptic drugs. | studies show that anti-epileptic drugs increase oxidative stress. thus, low-density lipoprotein oxidation increases and atherogenesis is induced. paraoxonase-associated high-density lipoprotein protects low-density lipoprotein and high-density lipoprotein oxidation. the effects of anti-epileptic drugs on paraoxonase activity has not been investigated yet. the aim of this study is to investigate the effect of anti-epileptic drugs on paraoxonase activity, lipid profiles, folat, vitamin b12, homocy ... | 2010 | 20519057 |
| surgery for malignant pleural mesothelioma. | the role of surgery for malignant pleural mesothelioma encompasses the need for rapid diagnosis, preoperative staging and surgical resection, and also the need for a greater biological understanding of this rare and aggressive malignancy. in the multimodality treatment paradigm, the goal of surgery is to provide a macroscopic complete resection (i.e., complete removal of all grossly visible tumor). two operations have evolved: extrapleural pneumonectomy and pleurectomy/decortication. the former ... | 2010 | 20524919 |
| polybrominated diphenyl ether (pbde) flame retardants and thyroid hormone during pregnancy. | human exposure to polybrominated diphenyl ether (pbde) flame retardants has increased exponentially over the last three decades. animal and human studies suggest that pbdes may disrupt thyroid function. although thyroid hormone (th) of maternal origin plays an essential role in normal fetal brain development, there is a paucity of human data regarding associations between exposure to pbdes and maternal th levels during pregnancy. | 2010 | 20562054 |
| laparoscopic colorectal surgery produces better outcomes for high risk cancer patients compared to open surgery. | the excellent outcomes reported for laparoscopic colorectal surgery in selected patients could also be potentially advantageous for high risk patients. this prospective study was designed to examine the feasibility and safety of laparoscopic resection in high risk patients with colorectal cancer. | 2010 | 20562603 |
| changes in temporomandibular joint disc position and form following herbst and fixed orthodontic treatment. | to determine the changes in the position and form of the temporomandibular joint articular disc in adolescents with class ii division 1 malocclusion and mandibular retrognathism treated with the herbst appliance (phase i) and fixed orthodontic appliance (phase ii). | 2010 | 20578854 |
| phylogenetic diversity of t4-like bacteriophages in lake baikal, east siberia. | among the tailed phages, the myoviruses, those with contractile tails, are widespread and diverse. an important component of the myoviridae family is the genus 't4-like viruses'. the present study was aimed at elucidating the molecular diversity of t4-type bacteriophages in lake baikal by partial sequencing of g23 genes of t4-type bacteriophages. our study revealed that the g23 gene sequences investigated were highly diverse and different from those of t4-like bacteriophages and from g23 clones ... | 2010 | 20579103 |
| is breast conservation therapy a viable option for patients with triple-receptor negative breast cancer? | triple-receptor negative breast cancers (tnbc) are aggressive neoplasms that lack estrogen-receptor, progesterone-receptor, and her-2 expressions. comparative analysis of breast conservation therapy (bct) versus mastectomy for tnbc is reported sparsely. we hypothesized that, despite its aggressive behavior, tnbc can be managed with bct. | 2010 | 20580045 |
| thyroid hormone receptor alpha1 downregulation in postischemic heart failure progression: the potential role of tissue hypothyroidism. | thyroid hormone (th) signaling is altered in response to various stresses including myocardial ischemia. the present study investigated potential implication of th signaling in the pathophysiology of postischemic remodeling. acute myocardial infarction was induced in rats by coronary artery ligation (ami). after 34 weeks, 6 animals were on congestive heart failure (chf) as indicated by measurements in lung and right ventricular weight. 7 animals were in compensated state (non-chf) and 8 sham-ope ... | 2010 | 20560106 |
| effect of celecoxib combined with thoracic epidural analgesia on pain after thoracotomy. | thoracotomy results in severe postoperative pain potentially leading to chronic pain. we investigated the potential benefits of oral celecoxib on postoperative analgesia combined with thoracic epidural analgesia (tea). | 2010 | 20581214 |
| [adult male with tubulointerstitial nephritis and uveitis syndrome complicated with thyroiditis]. | renal dysfunction was detected by routine medical examination in a 46-year-old man (blood urea nitrogen : 26 mg/dl, creatinine : 2.4 mg/dl and moderate proteinuria). a few weeks later, he visited a local ophthalmologist complaining of left eye pain and red eye. he was diagnosed as left uveitis, prescribed eye-drops and referred to our hospital for further examination. at the first visit, test results pointed to renal dysfunction and a high level of thyroid hormones (creatinine : 1.8 mg/dl, free ... | 2010 | 20560474 |
| goitrogenic/antithyroidal potential of green tea extract in relation to catechin in rats. | catechins are flavonoids found in abundance in green tea, have elicited high interest due to their beneficial effects on health. though flavonoids have been reported to have an antithyroid effect and also to be goitrogenic there have been no reports about the effect of green tea on rat thyroid. the present study was designed to examine whether high doses of green tea has any harmful effect on thyroid physiology. for this purpose green tea extract was administered orally to male albino rats for 3 ... | 2010 | 20561943 |
| the bispectral electroencephalogram during modified electroconvulsive therapy under propofol anesthesia: relation with seizure duration and awakening. | implication statement:: use of the bispectral electroencephalogram during modified electroconvulsive therapy (mect) under propofol anesthesia was found to be an accurate predictor of seizure duration and awakening. this may have potential clinical implications on therapeutic success and elimination of the undesirable effects associated with this treatment modality. | 2010 | 20562643 |
| congenital hypothyroidism. | congenital hypothyroidism (ch) occurs in approximately 1:2,000 to 1:4,000 newborns. the clinical manifestations are often subtle or not present at birth. this likely is due to trans-placental passage of some maternal thyroid hormone, while many infants have some thyroid production of their own. common symptoms include decreased activity and increased sleep, feeding difficulty, constipation, and prolonged jaundice. on examination, common signs include myxedematous facies, large fontanels, macrogl ... | 2010 | 20537182 |
| sewage bacteriophage inactivation by cationic porphyrins: influence of light parameters. | photodynamic therapy has been used to inactivate microorganisms through the use of targeted photosensitizers. although the photoinactivation of microorganisms has already been studied under different conditions, a systematic evaluation of irradiation characteristics is still limited. the goal of this study was to test how the light dose, fluence rate and irradiation source affect the viral photoinactivation of a t4-like sewage bacteriophage. the experiments were carried out using white par light ... | 2010 | 20563346 |
| eosinophilic vasculitis of the spinal cord associated with churg-strauss syndrome. | eosinophilic vasculitis has been described as part of churg-strauss syndrome (css), but it also affects the central nervous system in <10% of cases. however, spinal cord involvement in css has not been reported. we report a patient with myelopathic symptoms, with a two-year history of asthma. laboratory tests revealed leukocytosis, with 31.7% eosinophils. a chest computed tomographic scan and radiography showed patchy bilateral areas of consolidation, predominantly involving the peripheral regio ... | 2010 | 20538303 |
| identification of qtl associated with resistance to bacterial spot race t4 in tomato. | bacterial spot of tomato (solanum lycopersicum l.), caused by several xanthomonas sp., is a serious but difficult disease to control by chemical means. development of resistance has been hindered by emergence of races virulent to tomato, by the quantitative inheritance of resistance, and by a low correlation between seedling assays and resistance in the field. resistance to multiple races, including race t4, has been described in the s. lycopersicum var. cerasiformae accession pi 114490. we used ... | 2010 | 20563547 |
| molecular cloning and regulation of mrna expression of the thyrotropin β and glycoprotein hormone α subunits in red drum, sciaenops ocellatus. | full-length cdnas for thyrotropin β (tshβ) and glycoprotein hormone α (gsuα) subunits were cloned and sequenced from the red drum (sciaenops ocellatus). the cdnas for tshβ (877 bp) and gsuα (661 bp) yielded predicted coding regions of 126 and 94 amino acid proteins, respectively. both sequences contain all invariant cysteine and putative glycosylated asparagines characteristic of each as deduced by comparison with other gsuα and tshβ sequences from representative vertebrate species. multiple pro ... | 2010 | 20563882 |
| efficacy of intrauterine lignocaine plus vaginal misoprostol for pain relief in premenopausal women undergoing endometrial aspiration and ambulatory hysteroscopy. | to compare the effectiveness of a combination of intrauterine lignocaine and vaginal misoprostol in reducing pain at hysteroscopy and endometrial aspiration (ea). | 2010 | 20590504 |
| reconstruction using free jejunal transfer after resection of cancer of the upper oesophagus. | treatment of cancer of the upper part of the oesophagus is challenging. even after intended curative treatment, less than half of the patients are alive after five years. this retrospective study evaluates all the patients who had the upper oesophagus reconstructed by use of a free jejunal transfer following cancer resection from february 2000 to may 2008 at the university hospital of aarhus. | 2010 | 20591339 |
| medium-term results of neoadjuvant systemic chemotherapy using irinotecan, 5-fluorouracil, and leucovorin in patients with locally advanced rectal cancer. | the aim of this study was to evaluate the usefulness of neoadjuvant systemic chemotherapy using irinotecan, 5-fu, and leucovorin (lv) for the treatment of locally advanced rectal cancer, which was a powerful ploychemotherapy in those days in japan. | 2010 | 20538422 |
| sequential assembly of the wedge of the baseplate of phage t4 in the presence and absence of gp11 as monitored by analytical ultracentrifugation. | the baseplate wedge of bacteriophage t4 consists of seven gene products, namely, gp11, gp10, gp7, gp8, gp6, gp53, and gp25, which assemble strictly in this order with an exception that gp11 can bind to gp10 at any stage of the assembly. in this study, all the seven corresponding genes are expressed as recombinant proteins and all the possible combinations of the gene products are tested for interactions by analytical ultracentrifugation. no interactions among gene products that violate the stric ... | 2010 | 20593364 |
| surgery for renal cell carcinoma in two european urologic clinics: to compare or compete? | to evaluate and compare the incidence, tnm staging and the current strate- gy for the surgical treatment of renal cell carcinoma (rcc) in two european urologic institutions, situated in varna, bulgaria and in bari, italy. both clinics have sound experience of rcc surgery, and modern laparoscopic equipment. a retrospective chart review of all patients with rcc diagnosed and treated in the last year was conducted at the two sites. | 2010 | 20593709 |
| 2,3,7,8,12,13-hexaaryltruxenes: an ortho-substituted multiarm design and microwave-accelerated synthesis toward starburst macromolecular materials with well-defined pi delocalization. | we present herein a novel design and the efficient synthesis towards a "homogeneous" starburst fluorene system based on the novel 2,3,7,8,12,13-hexaaryltruxene scaffold. controlled microwave heating provides a facile and powerful approach for each step in the synthesis of these bulky materials with large steric hindrance, suggesting an avenue to access structurally well-defined complex organic semiconductors (oscs) rapidly and conveniently with high yield and purity. the resulting materials exhi ... | 2010 | 20564289 |
| [oral cancer surgery and oral cutaneous fistulas: risk factors]. | to quantify the oral cutaneous fistulae after surgery and to identify possible risk factors. | 2010 | 20549096 |
| examining the relationship between brominated flame retardants (bfr) exposure and changes of thyroid hormone levels around e-waste dismantling sites. | brominated flame retardants (bfrs) released from e-waste related activities may affect the health of local people. assessing the impact of e-waste exposure during recycling and dismantling activities on local people's thyroid hormone levels is an area of ongoing research. during november and december 2008, the process of e-waste recycling and dismantling was investigated, and 236 occupation-exposed people and 89 non-occupation-exposed people approximate to the e-waste recycling sites were survey ... | 2010 | 20598942 |
| discrimination of infectious bacteriophage t4 virus by propidium monoazide real-time pcr. | the advent of quantitative pcr has improved the detection of human viral pathogens in the environment. however, a serious limitation of this method may arise from the inability to discriminate between viruses that are infectious and viruses that have been inactivated and do not represent a human health hazard. to assess whether propidium monoazide (pma) pre-treatment is a good approach to inhibiting dna amplification from non-infectious viruses, bacteriophage t4 survival was measured using cell ... | 2010 | 20599560 |
| accuracy of multidetector computed tomography in identifying poor prognostic factors in colonic cancer. | recent neoadjuvant strategies for high-risk colonic tumours have renewed interest in accurate preoperative staging. the aim of this study was to validate prospectively the accuracy of multidetector computed tomography (mdct) in stratifying patients into good and poor prognostic groups in a multicentre setting. | 2010 | 20564305 |
| anterior approaches to the cervicothoracic junction: a study on the surgical accessibility of three different corridors based on the ct images. | to determine the location of left brachiocephalic vein (bcv) and tracheal bifurcation (tb) relative to the vertebral levels, and to ascertain the accessibility of three different corridors (c1: between the esophagus and trachea medially and the carotid sheath laterally, c2: between the right bcv and the brachiocephalic artery, and c3: between the ascending aorta and superior vena cava) for preoperative planning. from august 2008 to april 2009, normal chest ct scans of 150 subjects ranging in age ... | 2010 | 20549258 |
| sequential chemoradiotherapy in advanced laryngeal cancer: an institutional experience. | the objective of this study was to determine the efficacy of sequential chemoradiation for larynx preservation. | 2010 | 20565422 |
| changes in monoterpene emission rates of quercus ilex infested by aphids tended by native or invasive lasius ant species. | the emission of volatile organic compounds (vocs) depends on temperature and light. other factors such as insect herbivory also may modify voc emission. in particular, aphid feeding promotes the release of new compounds and changes the composition of plant volatile blends. given that some aphids are tended by ants, we investigated whether ants change the emission of vocs indirectly through attendance on aphids. the effect of lachnus roboris aphids and two different tending ant species on terpene ... | 2010 | 20549328 |
| ft4 immunoassays may display a pattern during pregnancy similar to the equilibrium dialysis id-lc/tandem ms candidate reference measurement procedure in spite of susceptibility towards binding protein alterations. | serum free thyroxine (ft4) testing in pregnancy is known to be challenging for immunoassays (ias). we verified the reliability of ft4 results by 3 commercial ias throughout pregnancy, by comparison of the pattern to that obtained with an equilibrium dialysis isotope dilution-mass spectrometry (ed id-ms) candidate reference measurement procedure. | 2010 | 20510682 |
| sentinel lymph node biopsy for papillary thyroid cancer: 12 years of experience at a single institution. | the purpose of this study was to report our experience with sentinel lymph node dissection (slnd) for papillary thyroid carcinoma, to evaluate the feasibility and safety of the procedure, and to examine its potential utility as a guide for central neck dissection. | 2010 | 20552407 |
| isolation and identification of acanthamoeba species related to amoebic encephalitis and nonpathogenic free-living amoeba species from the rice field. | isolation and characterization of the clinically relevant amphizoic amoebas in vegetated farmlands, which may present a risk to farmers' health. | 2010 | 20553339 |
| weight-of-evidence analysis of human exposures to dioxins and dioxin-like compounds and associations with thyroid hormone levels during early development. | thyroid hormones play a critical role in the proper development of brain function and cell growth. several epidemiological studies have been conducted to assess potential associations between pre- and post-natal exposure to dioxins or dioxin-like compounds (dlcs) and the levels of circulating thyroid hormones during early development. dioxins and dlcs include chlorinated dibenzo-p-dioxins, chlorinated dibenzofurans, and mono- and non-ortho polychlorinated biphenyls (pcbs). we identified a total ... | 2010 | 20416351 |
| transverse maxillary distraction in patients with periodontal pathology or insufficient tooth anchorage using custom-made devices. | we present our experience using modified hyrax devices for treating transverse deficiencies of the maxilla in adult patients with periodontal pathology or insufficient tooth anchorage. the surgical technique, clinical indications, and results are discussed. | 2010 | 20417007 |
| non-invasive measurement of thyroid hormone in feces of a diverse array of avian and mammalian species. | we developed and validated a non-invasive thyroid hormone measure in feces of a diverse array of birds and mammals. an i(131) radiolabel ingestion study in domestic dogs coupled with high pressure liquid chromatography (hplc) analysis, showed that peak excretion in feces occurred at 24-48h post-ingestion, with i(131)-labelled thyroid hormone metabolites excreted primarily as triiodothyronine (t3) and relatively little thyroxine (t4), at all excretion times examined. the immunoreactive t3 profile ... | 2010 | 20412809 |
| genotypic characterization of acanthamoeba spp. causing ocular infections in swedish patients: identification of the t15 genotype in a case of protracted keratitis. | the genus acanthamoeba represents free-living amoebae typically widespread in soil and water. it consists of more than 20 known species representing 15 genotypes of different pathogenicity and virulence. the aim of the study was the genotypic characterization of acanthamoeba spp. isolated from human keratitis cases in sweden. thirteen amoeba isolates obtained from contact lens users with suspected acanthamoeba keratitis (ak) were subjected to polymerase chain reaction amplification and subsequen ... | 2010 | 20524785 |
| management of gallbladder cancer. | resection is a means of improving survival in patients with gallbladder cancer. a more aggressive surgical approach, including resection of the gallbladder, liver, and regional lymph nodes, is advisable for patients with t1b to t4 tumors. aggressive resection is necessary because a patient's gallbladder cancer stage determines the outcome, not the surgery itself. therefore, major resections should be offered to appropriately selected patients. patients with advanced tumors or metastatic disease ... | 2010 | 20478489 |
| [homocysteinemia in polycystic ovary syndrome women]. | to compare serum homocysteine levels in polycystic ovary syndrome (pcos) and non-pcos women and correlate them with clinical, hormonal and metabolic parameters. | 2010 | 20512259 |
| frequency of subclinical thyroid dysfunction and risk factors for cardiovascular disease among women at a workplace. | subclinical thyroid dysfunction is very common in clinical practice and there is some evidence that it may be associated with cardiovascular disease. the aim here was to evaluate the frequencies of subclinical thyroid disease and risk factors for cardiovascular disease among women at a workplace, and to evaluate the association between subclinical thyroid disease and cardiovascular risk factors among them. | 2010 | 20512276 |
| pattern and amount of change after orthodontic correction of upper front teeth 7 years postretention. | to investigate the amount and pattern of changes of maxillary front teeth 7 years postretention, which previously were retained with a bonded retainer. | 2010 | 20482345 |
| squamous cell carcinoma of the temporal bone. | to study the survival outcomes of patients with squamous cell carcinoma (scc) of the temporal bone. a secondary purpose was to evaluate the university of pittsburgh staging system as a predictor of survival. | 2010 | 20513031 |
| early headgear effect on the eruption pattern of maxillary second molars. | to test the hypothesis that the use of a combination headgear (hg) during the first phase of orthodontic treatment has no effect on the eruption pattern of the maxillary second permanent molars. | 2010 | 20482348 |
| goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants. | environmental exposure of infants to perchlorate, thiocyanate, nitrate, might interfere with thyroid function. u.s. women with higher background perchlorate exposure have higher thyroid-stimulating hormone (tsh) and lower thyroxine (t4). there are no studies with individual measures of thyroid function and these goitrogens available in infants. | 2010 | 20439182 |
| age and the thyrotropin response to hypothyroxinemia. | some studies suggest altered pituitary functioning and tsh production with aging. | 2010 | 20484476 |
| sorafenib-induced hypothyroidism is associated with increased type 3 deiodination. | therapy with tyrosine kinase inhibitors is associated with thyroid dysfunction. decreased serum thyroid hormone levels during tyrosine kinase inhibitors are also observed in athyreotic patients with thyroid carcinoma. we therefore hypothesized that tyrosine kinase inhibitors may influence thyroid hormone metabolism. | 2010 | 20484486 |
| identification of a new motif in family b dna polymerases by mutational analyses of the bacteriophage t4 dna polymerase. | structure-based protein sequence alignments of family b dna polymerases revealed a conserved motif that is formed from interacting residues between loops from the n-terminal and palm domains and between the n-terminal loop and a conserved proline residue. the importance of the motif for function of the bacteriophage t4 dna polymerase was revealed by suppressor analysis. t4 dna polymerases that form weak replicating complexes cannot replicate dna when the dgtp pool is reduced. the conditional let ... | 2010 | 20493878 |
| the folding cooperativity of a protein is controlled by its chain topology. | the three-dimensional structures of proteins often show a modular architecture comprised of discrete structural regions or domains. cooperative communication between these regions is important for catalysis, regulation and efficient folding; lack of coupling has been implicated in the formation of fibrils and other misfolding pathologies. how different structural regions of a protein communicate and contribute to a protein's overall energetics and folding, however, is still poorly understood. he ... | 2010 | 20495548 |
| a randomized simultaneous comparison of acceleromyography with a peripheral nerve stimulator for assessing reversal of rocuronium-induced neuromuscular blockade with sugammadex. | we investigated the relationship between acceleromyography and a peripheral nerve stimulator for measuring reversal in patients administered sugammadex following rocuronium. | 2010 | 20523215 |
| analysis of serum lipid profiles, metal ions and thyroid hormones levels abnormalities in beta-thalassaemic children of bangladesh. | to assess the serum lipid profile of cardiovascular disease free male and female children with beta-thalassaemia. levels of zinc, copper and magnesium in the serum were also determined along with the thyroid profile. | 2010 | 20527607 |
| noxious colorectal distention in spinalized rats reduces pseudorabies virus labeling of sympathetic neurons. | the retrograde transsynaptic tracer pseudorabies virus (prv) has been widely used as a marker for synaptic connectivity in the spinal cord. notably, the prv-152 construct expresses enhanced green fluorescent protein (egfp). we recently reported a significant attenuation of prv-152 labeling of the intermediolateral cell column (iml) and celiac ganglia after complete t4 spinal cord transection versus sham injury in rats at 96 h after prv-152 inoculation of the left kidney. here we found a signific ... | 2010 | 20528165 |
| better late than early: delayed translation of intron-encoded endonuclease i-tevi is required for efficient splicing of its host group i intron. | the td group i intron interrupting the thymidylate synthase (ts) gene of phage t4 is a mobile intron that encodes the homing endonuclease i-tevi. efficient rna splicing of the intron is required to restore function of the ts gene, while expression of i-tevi from within the intron is required to initiate intron mobility. three distinct layers of regulation temporally limit i-tevi expression to late in the t4 infective cycle, yet the biological rationale for stringent regulation has not been teste ... | 2010 | 20497330 |
| cord blood thyroid-stimulating hormone and free t4 levels in turkish neonates: is iodine deficiency still a continuing problem? | the objectives of this study were to determine the cord blood thyroid-stimulating hormone (tsh) and free t(4) (ft(4) ) levels in turkish neonates and to determine whether these variables reveal iodine deficiency. | 2010 | 20497362 |
| effect of thyroid statuses on sodium/iodide symporter (nis) gene expression in the extrathyroidal tissues in mice. | abstract: | 2010 | 20529371 |
| [bacteriophage t4: molecular aspects of bacterial cell infection and the role of capsid proteins]. | bacteriophage t4 of the myoviridae family is ubiquitous in the environment and living organisms. in microbiology it has become a universal research model for the mechanisms of many biological processes, including bacteriophage infection. t4 phage is a tailed phage, the most frequent bacteriophage group. it is made up of a head, a contractile tail, and dsdna. its tail is a complex structure composed of a collar and its whiskers, a tail tube, a base plate, short fibers, and tail fibers. all these ... | 2010 | 20498502 |
| inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate. | thyroid gland explant cultures from prometamorphic xenopus laevis tadpoles were evaluated for their utility in assessing chemicals for thyroid hormone (th) synthesis disruption. the response of cultured thyroid glands to bovine thyroid stimulating hormone (btsh) and the th synthesis inhibitors methimazole, 6-propylthiouracil, and perchlorate was determined. thyroid glands continuously exposed for 12 days to graded concentrations of btsh released thyroxine (t4) in a dose-dependent manner. over ti ... | 2010 | 20530234 |
| intense therapy in patients with locally advanced esophageal cancer beyond hope for surgical cure: a prospective, multicenter phase ii trial of the swiss group for clinical cancer research (sakk 76/02). | there is no standard treatment for patients with locally advanced esophageal carcinoma without systemic metastasis in whom surgery is no longer considered a reasonable option. | 2010 | 20502056 |