Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| pharmacological and anatomical aspects of cholinergic activation of female sexual behavior. | forebrain infusion of cholinergic agonists activated the sexual response, lordosis, in ovariectomized female rats that had been primed with a low dose of estrogen. carbachol, an agonist with both muscarinic and nicotinic properties, and oxotremorine, an agonist with a primarily muscarinic action, produced dose-related increases in the frequency of lordosis elicited by stimulus male rats. this facilitation of lordosis was prevented when females were pretreated systemically with atropine or scopol ... | 1984 | 6494300 |
| differentiation of the sexually dimorphic nucleus in the preoptic area of the rat brain is inhibited by postnatal treatment with an estrogen antagonist. | the volume of the sexually dimorphic nucleus in the preoptic area (sdn-poa) of the rat brain is several fold larger in adult male rats that in adult females. this sex difference in brain structure was previously shown to develop under the influence of androgenic and estrogenic hormones during the perinatal period. we here report that treatment of newborn male and female rats with the estrogen antagonist tamoxifen significantly inhibited growth and differentiation of the sdn-poa in both sexes and ... | 1984 | 6610133 |
| suppression of sexual behavior and localization of [3h] puromycin after intracranial injection in the rat. | bilateral intracranial injections of puromycin (10 micrograms/0.5 microliter vehicle) into the preoptic area (poa) of steroid-primed ovariectomized rats resulted in a significant decrease in the lordosis response when compared to saline treated controls. to determine the extent of puromycin diffusion after intracranial injection, [3h] puromycin was injected into the right poa of ovariectomized rats. neural regions anterior, posterior and superior to the poa, and the right and left poa were asses ... | 1984 | 6514830 |
| changes in concentrations of estradiol nuclear receptors in the preoptic area, medial basal hypothalamus, amygdala, and pituitary gland of middle-aged and old cycling rats. | this study determined whether the biochemical characteristics of the estradiol (e2) nuclear receptor located in three different brain areas and the pituitary gland (pit) change in aging rats undergoing declining reproductive function. to measure maximal e2 nuclear receptor concentrations, groups of young (3-4 months old), middle-aged (8-11 months old), and old (16-18 months old) cycling rats were injected iv with e2 to translocate maximally cytosolic receptors into the nucleus. one hour later th ... | 1984 | 6537808 |
| effect of estrogen on lipoprotein lipase activity and cytoplasmic progestin binding sites in lean and obese zucker rats. | injections of 5 micrograms estradiol benzoate (eb) for 5 days resulted in decreases in the rate of body weight gain in both lean (fafa) and obese (fafa) zucker rats. eb administration also resulted in significant induction of cytoplasmic progestin binding sites in both hypothalamic-preoptic area (h-poa) and adipose tissues from rats of both genotypes. however, eb treatment significantly decreased lipoprotein lipase (lpl) activity in adipose tissue from lean, but not obese, zucker rats and the sa ... | 1984 | 6694985 |
| courtship stimulates aromatase activity in preoptic area of brain in male ring doves. | aromatase activity was quantified in vitro in different regions of the basal forebrain of male ring doves at various times after the initiation of courtship. by 24 h after the introduction of a female dove into the cage of a male, there was a significant, nearly two-fold, increase in aromatase activity which was confined to the ventromedial preoptic area (vm-poa) where enzyme activity was concentrated. this increase in aromatase activity, which was sustained through day 5 of courtship, presumabl ... | 1984 | 6745192 |
| a new gall-forming species of anguina scopoli, 1777 (nemata: anguinidae) on bluegrass, poa annua l., from the coast of california. | anguina pacificae n. sp. is described and illustrated from stem galls on bluegrass, poa annua l., from golf courses along coastal california. the females are characterized by constrictions in the anterior and posterior connections of the isthmus with the respective parts of the esophagus, the long multicellular columella, and the sharply pointed tail tip. males are dorsally curved after death; body width is increased markedly after 13 annuli in both sexes, and the tail is conical and with an acu ... | 1984 | 19294043 |
| ethylene-induced chlorosis in the pathogenesis of bipolaris sorokiniana leaf spot of poa pratensis. | endogenous ethylene of poa pratensis leaves infected by bipolaris sorokiniana was evaluated as a factor in leaf chlorosis during pathogenesis. detectable increases in endogenous ethylene of leaves of intact plants under normal ambient pressure occurred 12 hours after inoculation and was maximum at 48 hours; from 48 to 96 hours the ethylene progressively decreased. necrotic lesions surrounded by chlorotic halos occurred on infected leaves between 24 and 48 hours. midvein chlorosis interconnecting ... | 1984 | 16663644 |
| [pancreatic oncofetal antigen (poa)]. | recently, there has been an increasing interest in the diagnostic and prognostic usefulness of tumor-associated antigen of embryonic and fetal origin. many approaches have been attempted to make an early diagnosis of the pancreatic cancer, where a specific screening blood test for the pancreatic cancer is required. by using antiserum to fetal pancreas, banwo et al, discovered an oncofetal antigen that was present in human fetal pancreas, pancreatic tumor tissue, and sera from patients with the p ... | 1983 | 6882002 |
| changes in concentration of hypothalamic cytosolic progestin receptors at the initiation of pseudopregnancy in rats. | pseudopregnancy (psp) can be induced by a single injection of progesterone in cyclic rats and the administration of anti-progesterone serum can block the establishment of psp in cervically stimulated rats. to further investigate neuroendocrine mechanisms for the initiation of either psp or prolactin (prl) surges in connection with the neurotropic action of progesterone, cytosolic progestin receptors (prc) were identified and measured in preoptic (poa) and basal hypothalamic (bh) areas. chronolog ... | 1983 | 6686522 |
| effects on male sex behavior and preoptic dopamine neurons of hyperprolactinemia induced by mttw15 pituitary tumors. | we have earlier reported that dopamine (da) activity in the preoptic anterior hypothalamic (poa-ah) region of castrated rats is inhibited by testosterone and accelerated by prl. these results suggested that dopaminergic neurons may play an important role in male copulatory behavior, particularly in the attenuation of sex behavior reported to be associated with hyperprolactinemia. we have now examined the effects of severe hyperprolactinemia on the poa-ah da activity in association with any modif ... | 1983 | 6641626 |
| [evaluation of pancreatic oncofetal antigen (poa) in the diagnosis of pancreatic cancer]. | pancreatic oncofetal antigen (poa) is considered to be an oncofetal antigen for human pancreas, and its measurement seems to be useful in the diagnosis of pancreatic cancer. in this study, poa, cea, ferritin, bmg (beta 2 microglobulin) and afp either in sera in pancreatic juice were measured in patients with pancreatic cancer, chronic pancreatitis and other various diseases, and their diagnostic value was comparatively evaluated. poa showed the highest sensitivity for pancreatic cancer compared ... | 1983 | 6349542 |
| clinical application of the enzyme immunoassay for pancreatic oncofetal antigen. | pancreatic oncofetal antigen (poa) purified by us has been detected in sera of patients with carcinoma of the pancreas by the micro-ouchterlony method. in an attempt to improve the sensitivity and clinical usefulness of the serum poa assay, we established an enzyme immunoassay for poa and reported the results with this method. in this study, we investigated serum poa levels in pancreatic cancer and other diseases. the tissue localization of this poa in the pancreas was also studied. for the esta ... | 1983 | 6367597 |
| performance of dairy cows in midlactation fed high quality grass pasture and concentrate at three percents of energy requirements. | thirty multiparous cows rotationally grazed high quality grass pastures (predominantly dactylis glomerata and poa pratensis) for 140 days. stage of lactation was 54 to 192 days at beginning of trial. cows were offered concentrates to supply 33, 66, or 100% of requirements for net energy for lactation above maintenance; daily intakes by the three groups averaged 3.5, 7.7, and 11.5 kg. refusal of concentrate tended to increase with supplementation. average milk production was 19.2, 20.4, and 21.5 ... | 1983 | 6841749 |
| uptake of serotonin and norepinephrine in hypothalamic and limbic brain regions during the estrous cycle and the effect of neurotoxin lesions on estrous cyclicity. | the temporal pattern of hypothalamic and limbic aminergic activity during the estrous cycle has been measured by changes in the serotonergic and noradrenergic neuronal uptake during the regular estrous cycle. significant changes (p = 0.006, 0.01) in the uptake of 3h 5-ht and 3h ne were recorded in the suprachiasmatic nuclei (scn) at 1200 hours on proestrus. significant changes (p = 0.01, 0.018) in the uptake of 3h 5-ht in the preoptic area (poa) were found at 1200 hours on both diestrus and proe ... | 1983 | 6683584 |
| extrahypothalamic control of daily surges of prolactin secretion in pseudopregnant rat. | the role of the limbic forebrain structures in controlling twice daily surges of prolactin (prl) induced by cervical stimulation was investigated after acute or chronic deafferentation of the limbic forebrain afferents to the hypothalamus in rats. the preoptic area-roof section (poa-rs), which interrupted the rostral limbic afferents at the dorsal level of the anterior commissure, induced pseudopregnancy (psp) and initiated the same nocturnal prl surges as those initiated by the cervical stimula ... | 1983 | 6686520 |
| influence of preweaning nutrition on growth of angus calves provided a postweaning nutritional system resulting in discontinuous growth. | postweaning growth patterns and preweaning milk and forage intake were observed over a 4-yr period for 137 angus calves allowed either fescue-legume or fescue pastures preweaning. after weaning, calves grazed fescue pasture until spring for a slow growth phase and then fescue, orchard grass, bluegrass and ladino clover pastures for 4 mo. following this period, the calves were confined and fed shelled corn and a 36% crude protein supplement until they reached 12 mm of fat over the 12th rib. the s ... | 1983 | 6874620 |
| synaptic changes in the hypothalamus of the prepuberal female rat administered estrogen. | subcutaneous administration of estradiol benzoate (eb) to prepuberal female rats can advance vaginal opening, phasic pituitary gland luteinizing hormone (lh) secretion, and ovulation, presumably through a neural mechanism. this study investigated whether these effects are associated with changes in synaptic profiles in the arcuate nucleus of the hypothalamus (arc) and the preoptic area (poa). twenty-five-day-old female rats were administered eb, eb followed by progesterone on day 27, or oil vehi ... | 1983 | 6613905 |
| lesions of the medial preoptic area prevent the facilitation of maternal behavior produced by amygdala lesions. | in the present study we tested the hypothesis that the facilitation of maternal behavior produced by amygdala lesions is mediated through the medial preoptic area. different groups of animals sustained lesions of the corticomedial amygdala (group am), the medial preoptic area (group mpoa), both regions (group am-mpoa), the corticomedial amygdala and non mpoa control sites (group am-cx), and control sites (groups lc or sc). animals were tested for their maternal responses to foster pups presented ... | 1983 | 6657771 |
| purification and characterization of a pancreatic cancer-associated antigen (pcaa) from normal colonic mucosa. | the same antigenic substance as pancreatic cancer-associated antigen (pcaa), sharing an identical immunogenicity with gelder's poa, was isolated and purified from normal colonic mucosa. purified colonic pcaa (pcaac) is a glycoprotein with a molecular weight of approximately 600,000; it consists of 30% carbohydrates and 70% peptides, and appears to be an n-glycosidic glycoprotein. antiserum raised against purified pcaac showed one fused line with our original anti-pcaa antiserum to ascites fluid ... | 1983 | 6422827 |
| immunocytochemical identification of the mesotocin- and vasotocin-producing systems in the brain of temperate and desert lizard species and their modifications by cold exposure. | using immunofluorescent techniques, mesotocin (mt) and vasotocin (vt) neurosecretory systems were identified in the brain of different lizards: one temperate species living in southern france and three desert species coming from southern algeria. in the four species, mt and vt were shown to be synthesized in specific neurons located in the anterior preoptic area (poa), the supraoptic (son), paraventricular (pvn), and ventromedial (vmn) nuclei. the neurosecretory axons of the poa neurons terminat ... | 1983 | 6628979 |
| circadian variations in beta-endorphin concentrations in pituitary and in some brain nuclei of the adult male rat. | using both the 'punch' microdissection and a radioimmunological technique, circadian variations in beta-endorphin concentrations can be observed in the pituitary and in some discrete brain regions of the male rat (wistar cfy). animals were synchronized with light from 06.00 to 18.00 h, then darkness. water and food were available ad libitum. very well marked circadian rhythms were in evidence in the anterior lobe of the pituitary, the septum, the pons, the medulla oblongata and the cerebellum. t ... | 1983 | 6299465 |
| differential distribution of the pancreatic cancer-associated antigen (pcaa) and pancreatic tissue antigen (paa) in pancreatic and gastrointestinal cancer tissues. | pcaa, a glycoprotein antigen fractionated from the ascites fluid of a patient with pancreatic cancer and sharing an identical immunogenicity with gelder's poa, and paa, a novel pancreatic tissue antigen, were studied immunohistologically. serial paraffin sections were prepared from surgical specimens of 11 cases of pancreatic cancer, 15 of gastric cancer, 12 of colonic cancer, and 2 of gallbladder cancer; these were then subjected to immunofluorescence and immunoperoxidase stainings. in noncance ... | 1983 | 6367596 |
| effects of psychotropic drugs microinjected into the hypothalamus on muricide, catalepsy and cortical eeg in ob rats. | in order to elucidate the mechanism of anti-muricide action of psychotropic drugs in the brain, the present study examined influences of these drugs microinjected into the hypothalamus on muricide. inhibition of muricide by chlorpromazine (cpz) was found both in the lateral preoptic area (1-poa) and the posterior part of the lateral hypothalamus (p-lh), and that by chlordiazepoxide was seen only the mammillary body. these effects were accompanied by a drowsiness of cortical eeg. anti-muricide ac ... | 1983 | 6300937 |
| serum pancreatic oncofetal antigen: its clinical usefulness for screening pancreatic cancer in combination with tests for other tumor markers. | screening for pancreatic cancer was carried out by serum pancreatic oncofetal antigen (poa) tests in 440 out-patients with abdominal complaints, with concomitant assay of carcinoembryonic antigen, alpha-fetoprotein and ferritin. poa was positive in 13 patients, of whom 3 cases of pancreatic cancer, and 4 of other malignant diseases were diagnosed while the remaining 6 were non-malignant. of these out-patients, 5 cases were finally diagnosed as having pancreatic cancer by further examinations. of ... | 1983 | 6197338 |
| vincristine, doxorubicin and mitomycin (vam) in patients with advanced breast cancer previously treated with cyclophosphamide, methotrexate and fluorouracil (cmf). a clinical trial of the piedmont oncology association (poa). | thirty-six evaluable patients with advanced breast cancer who had failed prior cmf therapy [15 (42%) as adjuvant treatment and 21 (58%) for advanced disease] were treated with a combination of vincristine, doxorubicin, and mitomycin (vam). there was one cr and 10 pr, giving a response rate of 31% (p, 95% confidence interval, 15%-47%). response was not significantly related to age, performance status, disease-free interval, dominant site of disease, number of sites of disease, or estrogen recepto ... | 1983 | 6354509 |
| [pancreatic oncofetal antigen (poa)--its characterization and the result of enzyme immunoassay]. | our studies on the partial purification, characterization and clinical application of pancreatic oncofetal antigen (poa) are presented. this antigen was purified from fetal pancreas and migrated in beta-region electrophoretically. its molecular weight was estimated approximately 80 x 10(4) daltons on gel filtration. poa prepared by us was different from either nishida's poa biochemically or shimano's pcaa immunologically. enzyme immunoassay of poa was established by conjugating with anti-poa wit ... | 1983 | 6349543 |
| characterization of estradiol receptors in brain cytosols from perinatal ferrets. | studies were undertaken to characterize the binding of [3h]estradiol ([3h]e2) to blood plasma and to brain cytosols collected from perinatal ferrets of both sexes. a dialysis experiment showed that the binding capacity of plasma for [3h]e2 was low in neonatal ferrets. saturable, high-affinity binding of [3h]e2 to cytosols prepared from ferret hypothalamus + preoptic area (h + poa), basal temporal lobe, and midbrain + brainstem (sexes pooled) was demonstrated 5 days prior to the date of expected ... | 1983 | 6857750 |
| [recent progress in tumor markers of the digestive system]. | recent progress in our tumor marker study of the digestive system was described. of carcinoembryonic antigen (cea), we developed a new assay system for detecting the cea derived from gastrointestinal tumor tissues selectively, and succeeded to diagnose 72% of colorectal cancer patients including dukes' a and b classifications. of mucus antigens, intestinal ima and gastric gma, both were fractionated and purified in our laboratory, were demonstrated to be useful markers in detecting carcinofetal- ... | 1983 | 6876437 |
| prolactin and lh release induced by kainic acid administration within the preoptic-suprachiasmatic region in behaving male rats. | adult male rats were chronically implanted with a multiple metal cannula assembly to allow for the administration of kainic acid within the poa-sch region. kainic acid was applied in its solid form at two dose levels: 2 micrograms and 4 micrograms. a chronic heart cannula implanted through the external jugular vein allowed for sequential blood sampling. animals were subjected to two different regimes, with 2-3 days difference, one in which blood sampling took place without kainic acid administra ... | 1983 | 6641886 |
| effects of discrete lesions of the sexually dimorphic nucleus of the preoptic area or other medial preoptic regions on the sexual behavior of male rats. | the sexually dimorphic nucleus of the rat medial preoptic area (sdn-poa) has a volume five times larger in the adult male compared with that of the adult female. in the present study, the effects of discrete electrolytic destruction of the sdn-poa or other specific medial preoptic (mpoa) regions on masculine sexual behavior were determined in adult, sexually experienced male rats. small lesions encompassing the sdn-poa had no effect on the maintenance of copulatory behavior. lesions of similar s ... | 1983 | 6824962 |
| cathodal versus anodal stimulation within the preoptic-suprachiasmatic region in male rats: effects on the release of prolactin and luteinizing hormone. | the relative efficiency for the release of luteinizing hormone (lh) and prolactin after anodal and cathodal stimulation applied within the preoptic-suprachiasmatic region (poa-sch) was studied in adult male rats under pentobarbital anesthesia. single monopolar pulses 0.5 ms duration, 100 or 200 microa intensity, were applied within the dorsal [vertical (v) 7.3] or ventral (v 7.8 to 7.9) aspects of the poa-sch at a mean rate of 10 hz in 30-s trains every other 30 s for a period of 30 min. blood s ... | 1983 | 6832271 |
| a regional analysis of estrogen binding to hypothalamic cell nuclei in relation to masculinization and defeminization. | gonadal steroids masculinize and defeminize neuroendocrine development, including behavior. defeminization makes males less sensitive than females to estrogen for showing female sexual behavior and cyclic gonadotropin secretion. masculinization makes males more sensitive than females to estrogen for showing male sexual behavior. thus masculinization and defeminization produce opposite effects on estrogen sensitivity. to study the relationship between estrogen sensitivity and estrogen binding, we ... | 1983 | 6842286 |
| sex differences in cholinergic enzymes of diagonal band nuclei in the rat preoptic area. | activities of choline acetylase (cat), synthetic enzyme for acetylcholine, and acetylcholine esterase (ache), degradative enzyme for acetylcholine, were measured in preoptic nuclei of gonadectomized, estradiol-treated male and female rats. estradiol-dependent enzymatic changes were localized within discrete poa nuclei and both the location and direction of the changes were dependent on the sex of the rat. estradiol administration increased cat and ache activity in the nucleus of the horizontal l ... | 1983 | 6877524 |
| [pancreatic cancer-related antigen (pcaa) and pancreatic tissue antigen (paa)--their chemical compositions, tissue localization, and clinical significance]. | pcaa, a glycoprotein antigen identified and purified from ascited fluid of a pancreatic cancer patient and sharing the identical immunogenicity with gelder's poa (shimano, 1981) and paa, a novel pancreas tissue antigen (loor, 1981) purified from saline extract of human pancreas were studied. (1) chemical composition: the purified pcaa from ascites fluid of a pancreatic cancer patient has a molecular weight of 10,000,000. the same antigenic substance as pcaa was also isolated and purified from no ... | 1983 | 6881993 |
| gastrointestinal tumor markers, other than carcinoembryonic antigen, and alpha fetal protein. | oncofetal markers for colon carcinomas are csap, a nonsulfated mucin, a second trimester fetal antigen, an altered thymidine kinase, a monosialoganglioside, and glycolipid antigens. for gastric carcinoma, they are basic fetoprotein, a sulfoglycoprotein, and for pancreatic carcinomas--poa, an oncofetal pancreatic antigen, and designated as capi, an oncofetal antigen. tumor-associated markers for colon carcinomas are: udp-galactosyltransferase and zinc glycinate marker; for gastric carcinomas, sul ... | 1983 | 6883374 |
| auditory spatial alternation transforms auditory time. | recent research has shown that a sequence of auditory events that is alternated between the ears is stretched out in auditory memory, as compared with nonalternating sequences. although the stimulus-onset asynchronies (soas) of the interaural and monaural sequences were the same, the perceptual-onset asynchronies (poas) differed by 24 msec. because this result was only established for a restricted range of soas (125-250 msec), the present study tested a much larger range (40-2,130 msec). it turn ... | 1983 | 6227698 |
| type 3 fimbriae of klebsiella sp.: molecular characterization and role in bacterial adhesion to plant roots. | type 3 fimbriae of klebsiella were purified and characterized. the fimbriae were 4 to 5 nm in diameter and 0.5 to 2 microns long. in sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the fimbrillin had an apparent molecular weight of 23,500, and it differed from enterobacterial type 1 fimbrillins in its amino acid composition. hydrophobic amino acids comprised 33.6% of all amino acids in the fimbrillin, which lacked cystine, phenylalanine, and arginine. serologically, the type 3 fimbria ... | 1983 | 6135689 |
| a role for somatostatin in the control of hamster growth. | concentrations of somatostatin-like immunoreactivity (srif-li) were measured in cerebral cortex, hippocampus, septum-poa, median eminence, gastric antrum, fundus and pancreas in adult female hamsters to determine whether changes in somatostatin could be related to increased growth hormone (gh) secretion and somatic growth that follow bilateral transections of hippocampus (n = 18; 17 controls). in addition, choline acetyltransferase (cat) activity was measured in the four brain regions in hippoca ... | 1983 | 6140995 |
| interaural and monaural clicks and clocks: tempo difference versus attention switching. | we describe a quantitative model capable of explaining the results of all reported investigations of the counting of interaural and monaural click sequencies. the model is developed by means of three convergent operations: (a) reanalyzing absolute-estimation data of apparent repetition rates of interaural and monaural sequences, (b) deriving interaural and monaural counting times from numerosity-judgement data, and (c) analyzing the time that observers needed to respond to the end of interaural ... | 1982 | 6212632 |
| residues in the fat of ewes grazing on soil contaminated with halogenated hydrocarbons. | three halogenated hydrocarbon compounds were applied to the surface of each of two .57 ha bluegrass plots in october. each plot was stocked with 10 mature ewes 6 mo after application. supplemental feed was not offered. five ewes remained on the plots for 180 d, whereas the other five were removed and replaced at 60-d intervals. average soil residues for the period of grazing were 13.3, 3.8, 29.3 and 32.8 mg/m2 hcb (hexachlorobenzene), dde [1,1-dichloro-2,2-bi(p-chlorophenyl)ethylene], ddt [1,1,1 ... | 1982 | 6294042 |
| changes in estrogen and progestin receptor binding resulting from retrochiasmatic knife cuts. | retrochiasmatic frontolateral knife cuts (flc) or sham operations (sham) were performed with a halasz-type knife. all animals were primed with estrogen plus 0.5 mg progesterone (p) and tested for lordosis both before and after surgery. two weeks after the last test they received estradiol (e2) in silastic capsules and were sacrificed 2 days later for determination of either nuclear estrogen receptors or cytosol progestin receptor binding in brain and pituitary (pit). rats which had received flc ... | 1982 | 6890690 |
| inhibition of the postovariectomy depletion of hypothalamic luteinizing hormone releasing hormone (lhrh) by suckling. | a study was undertaken to further the understanding of the mechanism by which suckling inhibits the release of pituitary lh and depresses the postovariectomy rise of plasma lh in lactating mammals. to that end, the effect of suckling (10 pups/animal) for 1 or 3 weeks on the lhrh content of the hypothalamus and preoptic area (poa) in ovariectomized and intact rats was examined. controls consisted of intact and 1 or 3 week ovariectomized, nonlactating animals. following decapitation, the brains we ... | 1982 | 7044434 |
| in vivo biosynthesis of hypothalamic luteinizing hormone releasing hormone in individual free-running female rats. | the present studies examined the feasibility of performing in vivo biosynthetic studies of hypothalamic lhrh in preoptic area cannulated individual ovariectomized, estradiol benzoate (eb)-progesterone (p) treated rats. one day after eb treatment, rats were bilaterally cannulated in the anterior ventromedial preoptic area (poa). the following day, rats were treated with p, and a mix of 3h-proline and 3h-leucine (500 muci) was continuously infused (for 8 hr) into the poa using an alzet osmotic min ... | 1982 | 7044767 |
| antidromic identification of neurons in the ventrolateral part of the medulla oblongata with ascending projections to the preoptic and anterior hypothalamic area (poa/aha). | seventy neurons in the ventrolateral medulla oblongata were antidromically activated by electrical stimulation of the preoptic and anterior hypothalamic area (poa/aha) in female rats under urethane anesthesia. these identified cells were located within and adjacent to the nucleus reticularis lateralis and could be readily distinguished into at least two types of neurons, designated as "fast' and "slow' cells, on the basis of their waveform and conduction velocity. | 1982 | 7059819 |
| acute thermoregulatory effects of unilateral electrolytic lesions of the medial and lateral preoptic area in rats. | unilateral anodal lesions of the medial or lateral preoptic area (poa) in unanesthetized rats had opposite thermoregulatory effects immediately after the lesion were made. lesions of the medial poa evoked hyperthermias and accompanying cold defense responses, including vasoconstriction of the tail, increased oxygen consumption, shivering, and heat conservation postures. the hyperthermias had latencies of 0-30 minutes and reached maximum values within 120 minutes postlesion. they were independent ... | 1982 | 7079312 |
| mechanisms for induction of drinking with special reference to angiotensin ii. | the japanese quail drinks water vigorously after water deprivation, haemorrhage and administration of hypertonic saline solution. most avian species responded to angiotensin ii (aii) by drinking, but carnivorous birds and those originating in arid regions were insensitive. the receptive sites for aii were the subfornical organ (sfo) and the preoptic area (poa) in the japanese quail. catecholaminergic fibers proceed from the poa to the sfo. dipsogenic information generated by aii at the poa is tr ... | 1982 | 6124337 |
| alteration of muscarinic binding in specific brain areas following estrogen treatment. | systemic administration of estradiol benzoate (eb) to ovariectomized female rats significantly altered cholinergic muscarinic binding of [3h]quinuclidinyl benzilate in discrete brain regions. specifically, eb increased muscarinic binding in the medial basal hypothalamus (mbh) and decreased muscarinic binding in the medial preoptic area (poa). these alterations were dose-dependent and appeared to reflect changes in the number of muscarinic binding sites. treatment with eb failed to significantly ... | 1982 | 7104717 |
| differentiation of the sexually dimorphic nucleus in the preoptic area of the rat brain is determined by the perinatal hormone environment. | the volume of a sexually dimorphic nucleus in the preoptic area (sdn-poa) of the rat brain is several fold larger in males than in females. when female rats were treated pre- and postnatally with testosterone propionate (tp) their sdn-poa developed equivalent in size to that of normal males. the results indicate that the gross morphological sex difference in sdn-poa volume is exclusively controlled by the hormonal environment during the critical period of sexual brain differentiation. | 1982 | 7162691 |
| cyclo (his-pro): mapping hypothalamic sites for its hypothermic action. | hypothalamic loci of sprague-dawley rats were individually injected with cyclo (his-pro) to determine the sites where that metabolite of thyrotropin-releasing hormone acts to produce hypothermia. there was almost always a positive hypothermic response in the preoptic-anterior hypothalamic area (poa/aha); injection into the posterior or middle hypothalamic areas or into the hippocampus caused no significant decrease in core temperature. the fact that only injection into the poa/aha evoked hypothe ... | 1982 | 7171986 |
| [identification of pancreatic oncofetal antigen (poa) and its clinical significance]. | 1982 | 7176116 | |
| changes in dendritic spine density in the preoptic area of the female rat at puberty. | preoptic area (poa) neurons stained by a modification of the golgi-kopsch method were studied in developing female rats. particular attention was focused on dendritic spine densities as they might be altered in relation to the onset of puberty. neurons in the anterior superior and posterior superior portions of the poa showed an increase in mean spine density at the age of vaginal opening. the increase in dendritic spine density in the posterior inferior quadrant of poa occurred prior to vaginal ... | 1982 | 7093733 |
| changes in aromatase activity in the rat brain during embryonic, neonatal, and infantile development. | we assessed the activity of the aromatase enzyme complex in slices of brain from rats by measuring the release of 3h2o from [1 beta-3h]testosterone. in hypothalami from 12-day-old rats, the rate of aromatase activity was linear with time and amount of tissue. the reaction was saturated at a substrate concentration of 0.1 microm, and the apparent km of the reaction was 27 nm. the production of 3h2o was inhibited by 4-hydroxyandrostenedione, with an apparent ki of 20 nm. aromatase activity was fir ... | 1982 | 7094885 |
| forebrain lordosis inhibiting system and serotonin neuron in female rats: effect of p-chloroamphetamine. | relationship between forebrain lordosis inhibiting system and serotonergic mechanism was examined in estradiol benzoate (eb) and progesterone (p)-primed ovariectomized rats. in order to remove the forebrain inhibition of lordosis response, anterior roof deafferentation (ard) which interrupts the dorsal inputs to the poa coming down anterior to the anterior commissure or medial preoptic area lesions (poa-l) were made. all experimental females pretreated with eb and p showed high levels of lordoti ... | 1982 | 7151745 |
| allergenic cross-reactivity of cytochromes c of kentucky bluegrass and perennial ryegrass pollens. | the allergenic cross-reactivity of cytochromes c isolated from kentucky bluegrass (kbg) and ryegrass (rg) pollens was demonstrated by the finding that both cytochromes elicited pca reactions of comparable titers in rats sensitized with murine reaginic antiserum to either kbg or rg cytochrome c. however, allergenic differences were revealed at limiting doses of the cytochromes c; under these conditions rg cytochrome c elicited pca reactions only with the homologous reaginic serum, whereas kbg cyt ... | 1982 | 6298610 |
| effects of short-term exposure to catecholestrogens on catecholamine turnover in the preoptic-hypothalamic brain of ovariectomized rats. | the effects of a series of catecholestrogens (2-hydroxyestrogens and 4-hydroxyestrogens) were compared to those of a primary estrogen, ethynylestradiol (ee2), on the catecholaminergic system in the preoptic-hypothalamic rat brain. adult ovariectomized rats received single injections (100 microgram s.c.) of ee2, 2-hydroxyestradiol (2-ohe2), 2-hydroxyethynylestradiol (2-ohee2), 4-hydroxyestradiol (4-ohe2) or 4-hydroxyethynylestradiol (4-ohee2). eight hours after estrogen administration the animals ... | 1982 | 6286038 |
| a reduction in the concentration of immunoreactive corticotropin, melanotropin and lipotropin in the brain of the aging rat. | we have previously shown that the hypothalamic concentration of immunoreactive alpha-melanotropin (alpha-mshi) is markedly lower in the aging female rat than in the young rat. the current view is that alpha-msh is derived from corticotropin (acth), and acth, in turn, is derived from a large molecular-weight precursor (pro-opiocortin); pro-opiocortin also serves as the precursor to beta- and gamma-lipotropin (lph). to ascertain if the age-related reduction in the concentration of alpha-mshi may b ... | 1982 | 6322911 |
| molecular-weight profiles of immunoreactive corticotropin in the hypothalamus of the aging rat. | extracts of the medial basal hypothalamus (mbh), the preoptic anterior hypothalamus (poa), or the pituitary gland of young (4-month-old) and old (18-month-old) female rats were fractionated on columns of sephadex g-75 superfine. five forms of immunoreactive corticotropin (acthi) were found in the mbh or poa: greater than 40k, 30-40k, 20-30k, 5.7k, and 4.5k. in contrast, 4 forms of acthi were found in the pituitary gland: 30-40k, 20-30k, 5.7k, and 4.5k. thus, hypothalamic tissue contains a large ... | 1982 | 6322912 |
| dissociation of the effects of gonadal steroids on brain serotonin metabolism and sexual behavior in the male rat. | steady-state concentrations of 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in anterior hypothalamus (ah), preoptic area (poa), suprachiasmatic nucleus (scn) and ventromedial nucleus (vmh) were equivalent 30 days after castration or sham operation in male rats killed at either the middle of the light or dark periods of a 12 : 12 h day/night cycle. chronic administration of testosterone, 5alpha-dyhydrotestosterone (dht), estradiol-17beta (e2) or e2+dht for 30 days to castrat ... | 1982 | 6173795 |
| chronic hyperprolactinemia depletes hypothalamic dopamine concentrations in male rats. | the tuberoinfundibular dopamine (tida) system appears to tonically inhibit pituitary prolactin secretion while moderate elevations in serum prolactin levels, in turn, augment the turnover rate of dopamine (da) without affecting the steady state concentrations of da in the tida neurons (1-5). the present study demonstrates that chronic elevations in serum prolactin, to greater than 2,000 ng/ml, induced by the prolactin secreting mttw15 tumor, decreased da concentrations by 47% in the median emine ... | 1982 | 7087668 |
| a functional dimorphism in the response of the hypothalamic-pituitary axis of prepubertal rats to steroid treatment. | in the present experiment we examined the circadian neural luteinizing hormone releasing hormone (lhrh) and serum luteinizing hormone (lh) response of prepubertal male and female rats under varying steroidal manipulations (intact, castrate, castrate + estradiol 17 beta [e2] + oil and castrate + e2 + progesterone[p]). prepubertal males demonstrated greater and acyclic lhrh concentrations in both the medial basal hypothalamus (mbh) and preoptic-suprachiasmatic regions (poa-sch) irrespective of ste ... | 1982 | 6751417 |
| brain grafts reverse hypogonadism of gonadotropin releasing hormone deficiency. | hypogonadism in the mutant hpg mouse is characterized by a deficiency of hypothalamic gonadotropin releasing hormone (gnrh). affected male mice exhibit immature reproductive organs, small abdominal testes and low pituitary and plasma gonadotropin concentrations. recent studies have demonstrated the potential of fetal brain transplants to establish functional connections with host tissues. we therefore sought to use this approach to correct the hpg deficit. fetal preoptic area (poa) (a site of gn ... | 1982 | 7045700 |
| morphological comparisons between xiphinema rivesi daimasso and x. americanum cobb populations from the eastern united states. | though in the past xiphinema americanum has been the most commonly reported dagger nematode in the eastern united states, our studies revealed the presence in pennsvlvania of a previously unrecognized and unreported species related to x. americanum, morphometric data and photomicrographs establish the identity of this form as x. rivesi and show expected variations in populations of this species from various locations. similar data and illustrations are given for x. americanum populations from pe ... | 1982 | 19295745 |
| description and sem observations of dolichodorus marylandicus n. sp. with a key to species of dolichodorus. | dolichodorus marylandicus n. sp. is described and illustrated from grass (zoysia japonica) in college park, maryland. specimens have also been collected from perennial bluegrass (poa pratensis) pasture at beltsville, maryland, and from pine (pinus sp.) in north carolina. this new species is related to d. heterocephalus cobb, d. similis golden, and d. aestuarius chow &taylor. females are distinct in having a longer styler and shorter body length than d. aestuarius. the excretory pore is at the le ... | 1981 | 19300733 |
| nematicide treatments of turfgrass seed. | seed treatments of improved kentucky bluegrass and fescue cultivars with carbofuran, oxamyl, and phenamiphos dissolved in acetone reduced seedling emergence, but treatments were not extremely phytotoxic. phenamiphos was the most toxic, particularly at the 5,000 mug/ml concentration. fresh weight of grass clippings 35 d following planting generally was greater in treatments than in controls except for the 5,000 mug/ml phenamiphos treatments on certain cultivars. all nematicide seed treatments red ... | 1981 | 19300783 |
| [effects of hypothalamic deafferentation and estrogen on the distribution and content of hypothalamic lhrh (author's transl)]. | anterior (ahd), or complete (chd) hypothalamic deafferentation was performed in female rats to ascertain the origin of lhrh in the arcuate median eminence region (arc-me). furthermore, effects of estrogen on the distribution and content of hypothalamic lhrh in ahd castrated rats were examined to elucidate the mechanism of feedback action of estrogen. hypothalamic tissues were sectioned serially at 220 micrometers in thickness in the frontal plane and lhrh activity in each section was measured by ... | 1981 | 7015780 |
| disproportionate accumulation of immunoreactive corticotropin, melanotropin, and lipotropin in the brain of the maturing rat. | the accumulation of immunoreactive acth (acthi), alpha msh (alpha mshi), and gamma-lipotropin (gamma lphi) as a function of age (10-120 days) was determined in three regions of the brain of male rats: the medial basal hypothalamus (mbh), the preoptic anterior hypothalamus (poa), and the thalamus. in each region of the brain, the concentrations of acthi, alpha mshi, and gamma lphi increased with age. in the mbh, the increase occurred in such a manner that the molar ratio of alpha mshi to acthi re ... | 1981 | 6273125 |
| cytoplasmic and nuclear binding of estradiol in the brain and pituitary of old female rats. | the subcellular distribution of estradiol following the in vivo administration of 3h-estradiol, cytosol and nuclear estrogen receptor after in vitro incubation with 3h-estradiol were studied in young adult female rats (3-6 months old) and old female rats (over 18 months old). after intravenous injection of 3h-estradiol, with or without deithylstilbestrol pretreatment, significantly higher cytosol uptake of estradiol in the pituitary, dorsal hypothalamus and corticomedial amygdala (amyg) with con ... | 1981 | 7215820 |
| diagnosis of pancreatic cancer by pancreatic oncofetal antigen (poa) in pure pancreatic juice. | pancreatic oncofetal antigen (poa) was detected in the pure pancreatic juice by double immunodiffusion assay in a series of patients, using anti-poa prepared by immunizing rabbits with human fetal pancreas homogenate. the test was positive in as many as 72% of the patients with pancreatic cancer studied, whereas only less than 10% of patients with other diseases or normal controls were positive for this antigen, thus suggesting a potential usefulness of the pure pancreatic juice assay for poa in ... | 1981 | 7216142 |
| neurogenesis of the sexually dimorphic nucleus of the preoptic area in the rat. | the sexually dimorphic nucleus of the preoptic area (sdn-poa) of sprague-dawley rats is larger in volume in the male and hormone-dependent early in postnatal life. in the present study, we compared for each sex the time course of neuroblast proliferation which study, we compared for each sex the time course of neuroblast proliferation which forms sdn-poa or adjacent medial preoptic area (mpoa) neurons. additionally, we investigated whether there is a temporal gradient of production of neurons in ... | 1981 | 7217370 |
| effects of histamine implants in several brain regions on the release of prolactin in conscious adult male rats. | the levels of prolactin in the plasma of conscious male rats were determined at various times after an acute administration of histamine or a histamine releasing agent, compound 48/80, in three brain regions. the brain structures that were examined were, the caudal part of the preoptic area and anterior part of the anterior hypothalamic area (poa-aha), the arcuate nucleus-ventromedial nucleus region (arc-vmn) and the medial-basal amygdaloid nucleus of the limbic system (ame). a marked increase i ... | 1981 | 7217824 |
| effect of neonatal intrahypothalamic testosterone implants on cyclicity and adult sexual behavior in the female hamster. | to localize the neural sites of hormone action for sexual differentiation in the hamster, pellets containing 3 microgram testosterone were implanted directly in the preoptic area-anterior hypothalamus (poa-ah) and the ventromedial hypothalamus-arcuate regions of the hypothalamus of 3-day-old female hamsters. the poa-ah implants strongly enhanced the potential for ectopic mounts, rear mounts, and intromission patterns after adult testosterone treatment. 50% of the females with neonatal poa-ah imp ... | 1981 | 7219677 |
| allergenic relationships of two different antigens of kentucky bluegrass pollen. | two purified allergens, allergen c and kbg-1, isolated from kentucky bluegrass (kbg) pollen, were found to be antigenically distinct with respect to rabbit precipitating antisera produced separately to each allergen. on the other hand, allergen c and kbg-1 appeared to be allergenically identical in terms of the specificities evaluated with murine reaginic antisera produced to each of these allergens; whereas they appeared to be only partially identical when evaluated with respect to the ige anti ... | 1981 | 7263084 |
| para-osteo-arthropathies. a new theory and mode of treatment. | the clinical and research experience of para-osteo-arthropathies (poa) observed in paraplegia is presented. from clinical findings and our own research studies, a new theory regarding the etiopathogenesis of the ectopic ossifications has been elaborated. poa is a biological process in which new bone is formed in tissues which in the normal condition do not ossify. a 45ca kinetic study showed that poa are young bones with an active 'turnover'. the urinary hydroxyproline level, already increased f ... | 1981 | 6791273 |
| effects of thyrotropin releasing hormone on hypothalamic thermosensitive neurons of the rat. | the actions of thyrotropin releasing hormone (trh) were tested on the firing rat of temperature-sensitive and temperature-insensitive neurons in the rat preoptic/anterior area of the hypothalamus (poa). iontophoretic application of trh resulted in inhibition of the firing rate of temperature-insensitive, warm-sensitive and cold-sensitive neurons. the inhibitory response of cold sensitive neurons in trh was relatively mild, however, and 2 of 6 of these neurons inhibited by trh also displayed rebo ... | 1981 | 6791769 |
| [immunocytochemical characterization of neurosecretory systems producing mesotocin and vasotocin in the brain of several lacertidae]. | using immunofluorescent techniques vasotocin (vt) and mesotocin (mt) neurosecretory systems were identified in the brain of lacertidae: one european species and of two south-algerian species. in the 3 species mt and vt was shown to be synthetized in specific neurons located in the anterior preoptic area (poa), the supraoptic (son) and in the paraventricular (pvn) nuclei. the axons originating in son and pvn were ending either in the external zone of the rostral median eminence (me) near to the a ... | 1981 | 6800583 |
| [development of enzyme immunoassay for pancreatic oncofetal antigen (poa) (author's transl)]. | 1981 | 7024591 | |
| sequential inhibition of progesterone: effects on sexual receptivity and associated changes in brain cytosol progestin binding in the female rat. | the purpose of this study was to examine the role of cytosol progestin receptors (cprs) in the activation of mating behavior in the estrogen (e2) stimulated, ovariectomized rat, following the administration of a dose of progesterone (p; 2.5 mg) which is sufficiently large to inhibit the re-induction of sexual receptivity by subsequent p ('sequential inhibition'). in order to control for competition by unlabeled p in our binding studies, aliquots of cytosol supernatants were passed through lh-20 ... | 1981 | 7272758 |
| the influence of gonadectomy, androgen exposure, or a gonadal graft in the neonatal rat on the volume of the sexually dimorphic nucleus of the preoptic area. | although the volume of the sexually dimorphic nucleus of the preoptic area (sdn-poa) of the adult rat has been shown to be modified by the hormone environment early in postnatal life, the present study was performed to clarify several fundamental questions related to this process. this study was designed to evaluate the ability of exogenous testosterone propionate (tp), or a gonadal graft, to influence sdn-poa volume in rats which were gonadectomized as neonates. orchidectomy on day 1 resulted i ... | 1981 | 7288477 |
| effect of reserpine (serpasil) and chlorpromazine (largactil) on hypothalamic nuclei of adult female rat. | the effects of reserpine (serpasil) and chlorpromazine (largactil) on preoptic area (poa), supraoptic nucleus (son) and paraventricular nucleus (pvn) of hypothalamus were studied in female rats having 4-day normal oestrus cycle. 30 rats were treated with reserpine in three doses i.e. 0.5 mg, 1.0 mg and 1.5 mg/kg body weight, whereas 20 other rats were treated with chlorpromazine in two doses i.e. 5.0 mg and 10.0 mg/kg body weight. gomori positive neurosecretory neurons of the hypothalamus were s ... | 1981 | 7304196 |
| sequential inhibition of sexual receptivity by progesterone is prevented by a protein synthesis inhibitor and is not causally related to decreased levels of hypothalamic progestin receptors in the female rat. | in the estrogen-primed ovariectomized female rat, the administration of progesterone facilitates sexual receptivity and activates proceptivity for many hours. if the progesterone dose is large (e.g., 2.5 mg), a refractory period follows, during which time animals are less sensitive to additional progesterone. this refractory period has been termed "sequential inhibition" and has been correlated previously with decreased levels of cytosol progestin receptors in the mediobasal hypothalamus-preopti ... | 1981 | 7346568 |
| noradrenaline stimulates somatostatin release from incubated slices of the amygdala and the hypothalamic preoptic area. | neurotransmitter effects were studied on in vitro release of immunoreactive somatostatin (srif) from slices prepared from several regions of the rat brain: mediobasal hypothalamus (mbh), preoptic anterior hypothalamic area (poa) and amygdaloid complex (amy). potassium (k+, 56 mm) stimulated srif release in all structures tested in a calcium dependent manner. morphine, dopamine, gaba and serotonin did not modify srif release in any structure; noradrenaline (na) was not effective on mbh slices, bu ... | 1981 | 6114780 |
| telencephalic afferents in the goldfish: an anterograde degeneration study. | terminals of ascending afferents in the telencephalon of the goldfish were examined by the fink-heimer method, after the unilateral transection of the peduncular region containing the forebrain bundles. the ascending projections from the more caudal regions of the brain were seen mainly on the ipsilateral side of the lesion. the ascending forebrain bundles gave widely distributed terminals throughout the area dorsalis of the telencephalon, especially in the area dorsalis telencephali pars centra ... | 1981 | 6170392 |
| hyperprolactinemia counteracts the testosterone-induced inhibition of the preoptic area dopamine turnover. | the present study was undertake to determine the effects of hyperprolactinemia on dopamine (da) concentrations and turnover rates in the medial basal hypothalamus (mbh) and the preoptic area-suprachiasmatic nucleus region (poa-scn) in castrated and castrated, testosterone(t) implanted male rats. subcutaneous implants, which raised serum t levels to those found in intact rats, decreased serum lh to basal levels but did not alter da turnover in the mbh. anterior pituitary (ap) transplants under th ... | 1981 | 6115329 |
| tumor markers of pancreatic carcinoma. | there is no well-defined specific tumor marker for carcinoma of the pancreas. carcinoembryonic antigen (cea) and alphafetal protein (afp) are produced by some pancreatic cancer cells. a pancreatic oncofetal antigen (poa) cross-reacts with other malignant neoplasms and is not produced by all pancreatic carcinomas. an ammonium sulfate fraction (0-25%) from an aqueous extract of pancreatic carcinoma tissues contains an antigen cross-reacting with extracts of other pancreatic carcinomas and various ... | 1981 | 6168354 |
| detection of cross-reactive allergens in kentucky bluegrass pollen and six other grasses by crossed radioimmunoelectrophoresis. | using crossed immunoelectrophoretic analysis of an aqueous extract of kentucky bluegrass (kbg)pollen employing hyperimmune rabbit and sheep precipitating antibodies to kbg and various grasses we detected at least 33 antigenic components. the majority of these antigens were extractable from the pollen within a period of 14 min and possessed anodal electrophoretic mobility. the extensive recognition of antigens in the kbg extract by antibodies raised to false oat, and to the combined extracts of t ... | 1981 | 6169649 |
| nitrogen fixation (acetylene reduction) by klebsiella pneumoniae in association with 'park' kentucky bluegrass (poa pratensis l.). | turks of 'park' kentucky bluegrass reestablished in the greenhouse and inoculated with klebsiella pneumoniae (w6) showed significantly increased nitrogen fixation (acetylene reduction) compared with control turfs. mean ethylene production rates per pot were 368 nmol h-1 for k. pneumoniae treated turfs, 55 nmol h-1 for heat-killed k. pneumoniae treated turfs, and 44 nmol h-1 for untreated turfs. calculated lag periods before activity was observed were generally very short (less than 1 h). when 'p ... | 1981 | 7011516 |
| neurologic injuries, paraosteoarthropathies, and human leukocyte antigens. | the distribution of human leukocyte antigens (hla) a and b has been evaluated in the circulatory lymphocytes of 68 patients with spinal cord injury and 32 with severe head injury. paraosteoarthropathy (poa) was present in 43 spinal cord injury and 23 head injury patients. hla-b 18 was found in 25.7% of the subjects with poa. among 341 healthy subjects, the frequency of hla-b 18 was 7.6%. there is a 0% frequency in patients without poa. the frequency of the hla-b 18 antigen is significantly raise ... | 1980 | 7377941 |
| mounting and lordosis behavior in androgen primed ovariectomized rats: effect of dorsal deafferentation of the preoptic area and hypothalamus. | daily injections of 500 microgram testosterone propionate (tp) for 21 days induced mounting behavior in all of 10 castrated male rats and the mean mount frequency (mf) for 30 min was 32.4 +/- 6.6 (mean +/- s.e.). the same treatment with tp induced mounting behavior in 6 out of 8 ovariectomized rats (female control), but the mean mf was 2.8 +/- 0.7. eight out of 12 ovariectomized rats which received a horizontal half-circle cut anterior to the anterior commissure (anterior roof deafferentation, a ... | 1980 | 7460860 |
| evidence for the existence of a sexually dimorphic nucleus in the preoptic area of the rat. | the volume of an intensely staining component of the preoptic area of the male rat is markedly larger than that of the female. moreover, its volume in both sexes is altered by perinatal hormone exposure consistent with the view that this brain region undergoes hormone dependent sexual differentiation. the present study was carried out to determine if this sexually dimorphic area of the brain has a greater cell density than that of the surround, and if a unique population or distribution of cells ... | 1980 | 7440781 |
| excitability of female rat central gray cells with medullary projections: changes produced by hypothalamic stimulation and estrogen treatment. | 1. effects of estrogen on the excitability of 74 neurons in the central gray of the mesencephalon (cg) antidromically identified from the medulla were investigated extracellularly in female rats under urethan anesthesia. 2. the mean rate of spontaneous discharge of the identified cg cells was higher in estrogen-treated (2.9 hz) than in untreated ovariectomized rats (0.3 hz). in the estrogen-treated preparations, 18.5% of the identified cells had discharge rates exceeding 3.0 hz, while none were ... | 1980 | 7441319 |
| interruption of pseudopregnancy by rostral periventricular preoptic lesions in the female rat. | lesions made in the rostral periventricular region of the basal preoptic area (poa) effectively interrupted pseudopregnancy in female rats. however, lesions in the dorsal poa, lateral poa, nucleus and diagonal band of broca or nucleus accumbens failed to interrupt pseudopregnancy. this suggests that the rostral periventricular poa may play a stimulatory role in regulating prolactin release during pseudopregnancy. | 1980 | 7449748 |
| pancreatic oncofoetal antigen (poa): its frequency and localisation in humans. | pancreatic oncofoetal antigen (poa) has been isolated by affinity chromatography and used to standardise an immunoassay. poa was detected in foetal serum and in 97% of sera from 75 patients with carcinoma of the pancreas. raised levels were also found in 16% of sera from 43 patients with chronic pancreatitis and in 3 of 156 patients with related conditions. using an immunoperoxidase method, poa was regularly found in the foetal pancreas and in adult carcinoma of the pancreas. weak staining was f ... | 1980 | 7279697 |
| [plant antigens with immunological properties. iii. separation of a biologically active fraction in a grass pollen extract]. | in present paper a partial biochemical study concerning two grass pollens (poa pratensis and phleum pratense) is carried out. on sephadex g-75 three fractions were detected by an extract from the grass pollens. only the third fraction shows a biological activity and biochemical findings are in agreement with the presence of four polipeptidic subfractions of different molecular weights ranged between 10,000 and 14,500. specific additionals trials (ultracentrifugation, disc-electrophoresis, thyn-l ... | 1980 | 7247505 |
| drug prescribing practices of dentists in the bluegrass dental society area. | 1980 | 6937590 | |
| effects of pentobarbital on hypothalamic catecholamines and lrh activities. | pentobarbital (pnt) injection at 12.30 h to ovariectomized rats suppressed the lrh contents of the medial basal hypothalamus (mbh) in association with a significant fall in serum lh 60-90 min later. the lrh contents in the preoptic area (poa) were unchanged in pnt treated rats. a similar effect on lrh levels in the mbh was also evident in ovariectomized rats pre-treated with oestradiol benzoate. pnt administration rapidly reduced the noradrenergic (ne) turnover in the mbh and poa, whereas dopami ... | 1980 | 7006289 |
| purification and some properties of the main polymorphic form of acid phosphatase from poa pratensis seeds. | the main polymorphic form of acid phosphatase was isolated from poa pratensis seeds by chromatography on deae- and cm-cellulose and gel filtration on bio-gel p-100. the enzyme migrated as a single band in disc electrophoresis at ph 4.5 and 8.4. the purified enzyme is a glycoprotein of molecular weight about 33 000. carbohydrate content accounts for 40% of the total weight. the optimum ph is at 5.2 and the apparent km for p-nitrophenylphosphate, 0.55 mm. fluoride ions are non-competitive and zinc ... | 1980 | 7269976 |
| the role of protein synthesis in the hypothalamic mechanism mediating pyrogen fever. | the effects of inhibition of protein synthesis by anisomycin on the pathogenesis of fever and normal thermoregulatory processes were investigated in the conscious and unrestrained cat. subcutaneous administration of 5.0-25.0 mg/kg of anisomycin prevented the fever normally evoked by an intravenous infusion of either 1.0 ml (10(8) organisms) of a 1:10 dilution of s. typhosa or 1.0-5.0 ml (3.5 x 10(5)-2.1 x 10(7) cells/ml) of endogenous pyrogen. in addition, systemic pre-treatment with anisomycin ... | 1980 | 7470943 |
| gas-liquid chromatography for evaluating polysaccharide degradation by ruminococcus flavefaciens c94 and bacteroides succinogenes s85. | two predominant rumen cellulolytic bacteria, ruminococcus flavefaciens c94 and bacteroides succinogenes s85, were incubated with ground filter paper (whatman no. 1), cattle manure fiber, wheat straw, kentucky bluegrass, alfalfa, and corn silage as substrates. analyses of the initial substrate and the recovered residue after 48 h of static incubation showed that r. flavefaciens c94 was quantitatively more effective than b. succinogenes s85 in degrading total dry matter (32.3% versus 16.1%). howev ... | 1980 | 7189996 |
| blood plasma magnesium, potassium, glucose, and immunoreactive insulin changes in cows moved abruptly from barn feeding to early spring pasture. | cations and immunoreactive insulin in plasma were measured in 35 lactating cows moved abruptly to early spring pasture. after change of cows from grass-clover hay to fescue-bluegrass pasture containing 22 to 31 g potassium/kg dry matter, immunoreactive insulin of 5 holstein cows increased 30% in 5 days and averaged 45% above prepasture concentrations for 40 days. magnesium averaged 44% below prepasture content of plasma during this period and was correlated negatively with potassium -.17 and imm ... | 1980 | 6999040 |