Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| production of ifn-gamma and il-10 to shigella invasins by mononuclear cells from volunteers orally inoculated with a shiga toxin-deleted shigella dysenteriae type 1 strain. | volunteers were orally administered invasive, non-shiga toxin-producing shigella dysenteriae 1 to establish a challenge model to assess vaccine efficacy. in stepwise fashion, four separate groups were given 3 x 10(2), 7 x 10(3), 5 x 10(4), or 7 x 10(5) cfu. using pbmc, proliferative responses and cytokine production were measured to s. dysenteriae whole-cell preparations and to purified recombinant invasion plasmid ags (ipa) c and ipad. anti-lps and anti-ipa abs and ab-secreting cells were also ... | 2000 | 10657678 |
| effects of caffeic acid, chlorogenic acid and ferulic acid on growth and arylamine n-acetyltransferase activity in shigella sonnei (group d). | arylamine n-acetyltransferase (nat) activities with 2-aminofluorene (2-af) as substrates were determined in shigella sonnei (group d) collected from patients with diarrhoeal disease. the nat activity was determined using an acetyl coa recycling assay and high pressure liquid chromatography. inhibition of growth studies from s. sonnei (group d) demonstrated that caffeic acid (ca), chlorogenic acid (cga) and ferulic acid (fa) elicited a dose-dependent bactericidal effect in s. sonnei (group d) cul ... | 2000 | 10677842 |
| evaluation of antibacterial activity of asparagus racemosus willd. root. | different concentrations (50, 100, 150 microg/ml) of the methanol extract of the roots of asparagus racemosus willd. showed considerable in vitro antibacterial efficacy against escherichia coli, shigella dysenteriae, shigella sonnei, shigella flexneri, vibrio cholerae, salmonella typhi, salmonella typhimurium, pseudomonas putida, bacillus subtilis and staphylococcus aureus. the effects produced by the methanol extract were compared with chloramphenicol. | 2000 | 10685109 |
| an outbreak of dysentery in a rural district of zimbabwe: the role of personal hygiene at public gatherings. | to characterize the nature and extent of the outbreak; to determine the risk factors associated with contracting shigellosis; and to institute disease control and preventive measures. | 2000 | 11235056 |
| [effect of irradiation on the shelf-life of aquatic products]. | the effect of irradiation at doses of 0-10 kgy on the shelf-life of aquatic products was determined. the results showed that irradiation could not prolong the shelf-life of aquatic products kept at 25 degrees c. while the aquatic products were kept at refrigerator (4 degrees c), the irradiation could prolong the shelf-life and effectively reduce the total aerobic plate count. irradiation could effectively reduce the number of coliform to less than 300/kg and eliminate shigella shigae, salmonella ... | 2000 | 12725095 |
| role of porin of shigella dysenteriae type 1 in modulation of lipopolysaccharide mediated nitric oxide and interleukin-1 release by murine peritoneal macrophages. | the ability of shigella dysenteriae type 1 porin to induce the release of nitric oxide (no) and interleukin-1 (il-1) from peritoneal macrophages of mouse and to regulate lipopolysaccharide (lps) and gamma interferon (ifn-gamma) mediated release of the two proinflammatory mediators was investigated. porin released nitrite when added to macrophage cultures. a maximum of 3.2-fold nitrite release by macrophages was observed with 100 ng ml(-1) of porin. the nitrite release of lps was enhanced signifi ... | 2000 | 11024352 |
| tonb is required for intracellular growth and virulence of shigella dysenteriae. | to assess the importance of tonb-dependent iron transport systems to growth of shigella in vivo, a tonb mutant of shigella dysenteriae was isolated and tested in cultured cells. the tonb mutant invaded epithelial cells, but did not form plaques in confluent monolayers of henle cells, indicating an inability of this mutant to spread from cell to cell. the rate of intracellular multiplication of the tonb mutant was reduced significantly compared to that of the wild type. the loss of virulence in t ... | 2000 | 11035742 |
| a new biological agent for treatment of shiga toxigenic escherichia coli infections and dysentery in humans. | gastrointestinal disease caused by shiga toxin-producing bacteria (such as escherichia coli o157:h7 and shigella dysenteriae) is often complicated by life-threatening toxin-induced systemic sequelae, including hemolytic-uremic syndrome. such infections can now be diagnosed very early in the course of the disease, but at present no effective therapeutic intervention is possible. here, we constructed a recombinant bacterium that displayed a shiga toxin receptor mimic on its surface, and it adsorbe ... | 2000 | 10700227 |
| antimicrobial agent resistance in bacterial isolates from patients with diarrhea and urinary tract infection in the sudan. | antimicrobial sensitivity tests were performed on four-hundred and ninety-seven bacterial isolates from sudanese patients with diarrhea or urinary tract infections. shigella dysenteriae type i and enteropathogenic escherichia coli showed high resistance rates (percentage of isolates showing antibiotic resistance) against the commonly-used antimicrobial agents: ampicillin, amoxicillin, chloramphenicol, tetracycline, cotrimoxazole, nalidixic acid, sulfonamide, and neomycin, and were completely sen ... | 2000 | 11421374 |
| [acute encephalopathy in children: a serious illness after an inauspicious beginning]. | three young children, 2 girls of 6 and 3.5 years and 1 boy aged 3.5 years, had complaints like vomiting and fever of what initially was thought to be a minor infection. however, their condition deteriorated within two days to such an extent that they died while being treated on the intensive care department. the rapid drop in consciousness, sometimes accompanied by convulsions, is an expression of increased intracranial pressure resulting from diffuse brain oedema, which itself is probably cause ... | 2000 | 10965363 |
| escherichia coli shiga toxin. | the stx family contains two types called stx1 (verotoxin 1: vt1 or shiga-like toxin: slt1) and stx2 (vt2, slt2); both toxins are encoded by bacteriophages. stx1 is identical to shiga toxin produced by shigella dysenteriae type i. stx2 is heterogeneous and immunologically different from stx1. although many variations are found in stx family, all stx has an a-b structure: the a subunit has n-glycosidase activity and the b subunit binds to a membrane glycolipid, globotriaosylceramide (gb3). the a s ... | 2000 | 10994531 |
| nmr spectroscopy, molecular dynamics, and conformation of a synthetic octasaccharide fragment of the o-specific polysaccharide of shigella dysenteriae type 1. | a synthetic octasaccharide fragment (2) of the o-specific polysaccharide (1) of shigella dysenteriae type 1 has been studied as its methyl glycoside by one- and two-dimensional homo- and heteronuclear nmr spectroscopy. complete 1h and 13c nmr assignments have been generated, and the 13c spin-lattice relaxation times have been measured for the octasaccharide 2. a congener (6) of this octasaccharide containing one d-galactose residue with a specific 13c label at c-1 has been synthesized and used t ... | 2000 | 10723612 |
| structural studies of the o-antigen polysaccharide from the enteroinvasive escherichia coli o164 cross-reacting with shigella dysenteriae type 3. | the structure of the o-antigen polysaccharide from escherichia coli o164 has been determined. nuclear magnetic resonance spectroscopy together with component and methylation analyses of lipid free polysaccharide were the principal methods used. the sequence of the sugar residues could be determined by noesy and heteronuclear multiple bond connectivity nmr experiments. it is concluded that the polysaccharide is composed of a pentasaccharide repeating unit with the following structure: [structure: ... | 1999 | 10561586 |
| structural studies utilizing 13c-enrichment of the o-antigen polysaccharide from the enterotoxigenic escherichia coli o159 cross-reacting with shigella dysenteriae type 4. | the structure of the o-antigen polysaccharide from escherichia coli o159 has been determined using primarily nmr spectroscopy of the 13c-enriched polysaccharide. the sequence of the sugar residues could be determined by heteronuclear multiple bond connectivity nmr experiments. the polysaccharide is composed of a pentasaccharide repeating unit with the following structure: [sequence: see text] matrix assisted laser desorption ionization mass spectrometry was performed on intact lipopolysaccharide ... | 1999 | 10542072 |
| mechanisms of quinolone resistance in clinical isolates of shigella dysenteriae. | 1999 | 10577351 | |
| verocytotoxins (shiga-like toxins) produced by escherichia coli: a minireview of their classification, clinical presentations and management of a heterogeneous family of cytotoxins. | bacterial virulence usually requires the interaction of multiple factors in order to cause disease. the enterotoxins produced by certain strains of bacteria are proteins which vary in their mode of action, but do fall into two general groups; the cytotoxic and the cytotonic enterotoxins. while cytotoxic enterotoxins typically kill eucaryotic cells (eg. by inhibiting protein synthesis), cytotonic enterotoxins derange cell metabolism in specific ways (eg. by elevating cyclic nucleotide levels). so ... | 1999 | 10465326 |
| shiga toxin 2 promotes the stem cell differentiation into granulocytes in the bone marrow causing marked granulocytosis in the peripheral blood. | 1999 | 10468138 | |
| emerging and re-emerging diseases--epidemic enterohaemorrhagic infections 100 years after shiga. | 1999 | 10470309 | |
| typing and characterization of mechanisms of resistance of shigella spp. isolated from feces of children under 5 years of age from ifakara, tanzania. | eighty-six strains of shigella spp. were isolated during the dry season from stool samples of children under 5 years of age in ifakara, tanzania. the epidemiological relationship as well as the antimicrobial susceptibility and mechanisms of resistance to ampicillin, chloramphenicol, and co-trimoxazole were investigated. four different epidemiological tools, pulsed-field gel electrophoresis (pfge), repetitive extragenic palindromic (rep)-pcr, plasmid analysis, and antibiogram, were compared for t ... | 1999 | 10488163 |
| effect of shiga toxin on nacl transport in rat distal colon. | shiga toxin causes net fluid secretion in rabbit jejunum by selectively targeting, and inhibiting protein synthesis in, absorptive villous cells. the effect of shiga toxin on the colon, where it is presumably produced, is not known. this study was undertaken to investigate the effect of shiga toxin on the rat distal colon. | 1999 | 10499478 |
| prevalence of shigella enterotoxins 1 and 2 among shigella strains isolated from patients with traveler's diarrhea. | shigella spp. are known primarily as a cause of bacillary dysentery. however, in an initial phase, numerous patients exhibit watery diarrhea that may or may not be followed by dysentery. new virulence factors associated with the species of shigella have recently been described. these are enterotoxins 1 and 2 of shigella (shet-1 and shet-2, respectively). the aim of the present study was to determine the prevalence of shet-1 and shet-2 in species of shigella isolated from patients with traveler's ... | 1999 | 10523561 |
| dr. kiyoshi shiga: discoverer of the dysentery bacillus. | the clinical manifestations of dysentery have been described for centuries, and the prototypic bacterial agent, shigella dysenteriae, was identified 100 years ago. in the english language there has been remarkably little written about dr. kiyoshi shiga, discoverer of the dysentery bacillus. we submit a brief biography of dr. shiga and the circumstances leading to his discovery, which proved the bacterial etiology of nonamebic dysentery. | 1999 | 10524979 |
| promiscuous origin of a chimeric sequence in the escherichia coli o157:h7 genome. | a novel sequence of 2.9 kb in the intergenic region between the muts and rpos genes of escherichia coli o157:h7 and closely related strains replaces a sequence of 6.1 kb in e. coli k-12 strains. at the same locus in shigella dysenteriae type 1, a sequence identical to that in o157:h7 is bounded by the is1 insertion sequence element. extensive polymorphism in the muts-rpos chromosomal region is indicative of horizontal transfer events. | 1999 | 10601221 |
| antibodies to shiga toxin in the serum of children with shigella-associated haemolytic uraemic syndrome. | antibodies to shiga toxin (stx) were measured in the sera of 49 children with shigella dysenteriae serotype 1 infection, of whom 17 had haemolytic uraemic syndrome (hus) and 32 had no complications (uncomplicated shigellosis, ucs). children with hus had lower levels of total igg and igm and lower igm titres to stx than those with ucs. the number of children with neutralising antibodies was similar in the two groups. of the children with hus, 11 had hus on enrolment and six developed hus subseque ... | 1999 | 9920120 |
| the aerobactin iron transport system genes in shigella flexneri are present within a pathogenicity island. | genes encoding the synthesis and transport of aerobactin, a hydroxamate siderophore associated with increased virulence of enteric bacteria, were mapped within a pathogenicity island in shigella flexneri. the island, designated shi-2 for shigella pathogenicity island 2, was located downstream of selc, the site of insertion of pathogenicity islands in several other enteric pathogens. dna sequence analysis revealed the presence of multiple insertion sequences upstream and downstream of the aerobac ... | 1999 | 10411724 |
| involvement of tumor necrosis factor alpha and interleukin-1beta in enhancement of pentylenetetrazole-induced seizures caused by shigella dysenteriae. | neurologic manifestations, mainly convulsions, are the most frequent extraintestinal complications of shigellosis. we used an animal model to study the roles of tumor necrosis factor alpha (tnf-alpha) and interleukin-1 beta (il-1beta) in shigella-related seizures. administration of shigella dysenteriae 60r sonicate enhanced the sensitivity of mice to the proconvulsant pentylenetetrazole (ptz) within 7 h. this was indicated by a significantly higher mean convulsion score and an increased number o ... | 1999 | 10024595 |
| intrafamilial person-to-person spread of bacillary dysentery due to shigella dysenteriae in southwestern saudi arabia. | to identify the factors that influence transmission of bacillary dysentry (bd) within families during a propagated outbreak of bacillary dysentery. | 1999 | 10750504 |
| comparison of six dose-response models for use with food-borne pathogens. | food-related illness in the united states is estimated to affect over six million people per year and cost the economy several billion dollars. these illnesses and costs could be reduced if minimum infectious doses were established and used as the basis of regulations and monitoring. however, standard methodologies for dose-response assessment are not yet formulated for microbial risk assessment. the objective of this study was to compare dose-response models for food-borne pathogens and determi ... | 1999 | 10765449 |
| laboratory surveillance of shigella dysenteriae type 1 in kwazulu-natal. | to collect data on the antimicrobial susceptibility of shigella dysenteriae type 1 in kwazulu-natal, including the testing of newer therapeutic agents, and to evaluate the ability of laboratories to participate in a provincial surveillance programme. | 1999 | 10070415 |
| the so-called chromosomal verotoxin genes are actually carried by defective prophages. | 1999 | 10382973 | |
| impaired imipenem uptake associated with alterations in outer membrane proteins and lipopolysaccharides in imipenem-resistant shigella dysenteriae. | three imipenem-resistant mutants were obtained from a clinical isolate (c152) of shigella dysenteriae by selection with increasing concentrations of imipenem. resistance to imipenem was associated with resistance to several other beta-lactam antibiotics. the penicillin-binding protein (pbp) patterns of the resistant and the wild-type strains were comparable. the permeability of the outer membrane proteins (omps) of the most resistant mutant, im16, was lower than that of the parent strain c152 wh ... | 1999 | 11252324 |
| lethality of a heat- and phosphate-catalyzed glucose by-product to escherichia coli o157:h7 and partial protection conferred by the rpos regulon. | a by-product of glucose produced during sterilization (121 degrees c, 15 lb/in2, 15 min) at neutral ph and in the presence of phosphate (i.e., phosphate-buffered saline) was bactericidal to escherichia coli o157:h7 (atcc 43895). other six-carbon (fructose and galactose) and five-carbon (arabinose, ribose, and xylose) reducing sugars also produced a toxic by-product under the same conditions. fructose and the five-carbon sugars yielded the most bactericidal activity. glucose concentrations of 1% ... | 1999 | 10347019 |
| shiga/verocytotoxins and shiga/verotoxigenic escherichia coli in animals. | vero/shiga toxins (vt/stx) have an a-b structure: the a subunit carries the enzymatic activity and the b subunit binds the toxin to the membrane receptor (gb3 or gb4). the vt/stx inhibit protein synthesis in the target eucaryotic cells, mainly the endothelial cells of blood vessels. the vt/stx are subdivided into two families. vt1/stx1 is a homogeneous family of toxins identical to the stx of shigella dysenteriae. vt2/stx2 is a more heterogeneous family of toxins more distantly related to this s ... | 1999 | 10367357 |
| sequence analysis of stx2-converting phage vt2-sa shows a great divergence in early regulation and replication regions. | in enterohemorrhagic escherichia coli, shiga toxin is produced by lysogenic prophages. we have isolated the prophage vt2-sa that is responsible for production of shiga toxin type 2 protein, and determined the complete nucleotide sequence of this phage dna. the entire dna sequence consisted of 60,942 bp, exhibiting marked similarity to the 933w phage genome. however, several differences were observed in the immunity and replication regions, where ci, cii, ciii, n, cro, o, and p genes were present ... | 1999 | 10492170 |
| risk factors for death in hospitalized dysentery patients in rwanda. | to evaluate the management of severe dysentery cases in in-patient facilities during an epidemic of shigella dysenteriae type 1 (sd1), and to identify the factors associated with the risk of death, we conducted a prospective cohort study in 10 rwandese hospitals between september and december 1994. data were obtained from 849 cases admitted to hospitals with diarrhoea and visible blood in stools. the proportion of patients with persistent bloody diarrhoea was 51.0% at treatment day 3 and 27.9% a ... | 1999 | 10444318 |
| global burden of shigella infections: implications for vaccine development and implementation of control strategies. | few studies provide data on the global morbidity and mortality caused by infection with shigella spp.; such estimates are needed, however, to plan strategies of prevention and treatment. here we report the results of a review of the literature published between 1966 and 1997 on shigella infection. the data obtained permit calculation of the number of cases of shigella infection and the associated mortality occurring worldwide each year, by age, and (as a proxy for disease severity) by clinical c ... | 1999 | 10516787 |
| purification and characterization of klebsiella pneumoniae cytotoxins. | isolation, purification and characterization of 3 new cytotoxins of a k. pneumoniae strain isolated from ready to eat pork sausage are reported. purification process involved extraction of cytotoxins with polymyxin b sulphate, salt precipitation, gel filtration and anion exchange chromatography. klebsiella cytotoxin (kct) i, a glycoprotein of about 65 kda was verocytotoxic, enterotoxic and dermonerotic. kct ii was erythemogenic, verocytotoxic and enterotoxic protein of co 55 kda, while kct iii w ... | 1999 | 10522158 |
| [the serum bactericidal activity of domestic fleroxacin and lomefloxacin]. | to evaluate antibacterial activities in vivo and in vitro of fleroxacin and lomefloxacin. | 1999 | 11798634 |
| role of nitric oxide in the enhancement of pentylenetetrazole-induced seizures caused by shigella dysenteriae. | convulsions and encephalopathy are frequent complications of childhood shigellosis. we studied the role of nitric oxide (no) in shigella-related seizures in an animal model. pretreatment of mice with shigella dysenteriae 60r sonicate elevated serum no levels and enhanced the convulsive response to pentylenetetrazole (ptz), as indicated by a higher mean convulsion score and a higher number of mice responding with seizures. treatment of the mice with s-methylisothiourea sulfate (smt), a potent inh ... | 1999 | 10569751 |
| activation of src family kinase yes induced by shiga toxin binding to globotriaosyl ceramide (gb3/cd77) in low density, detergent-insoluble microdomains. | shiga toxin (stx) is an enterotoxin produced by shigella dysenteriae serotype 1 and enterohemorrhagic escherichia coli, which binds specifically to globotriaosylceramide, gb3, on the cell surface and causes cell death. we previously demonstrated that stx induced apoptosis in human renal tubular cell line achn cells (taguchi, t., uchida, h., kiyokawa, n., mori, t., sato, n., horie, h., takeda, t and fujimoto, j. (1998) kidney int. 53, 1681-1688). to study the early signal transduction after stx a ... | 1999 | 10575015 |
| spontaneous tandem amplification and deletion of the shiga toxin operon in shigella dysenteriae 1. | only one species of shigella, shigella dysenteriae 1, has been demonstrated to produce shiga toxin (stx). stx is closely related to the toxins produced by shiga toxin-producing escherichia coli (stec). in stec, these toxins are often encoded on lambdoid bacteriophages and are major virulence factors for these organisms. although the bacteriophage-encoded stx genes of stec are highly mobile, the stx genes in s. dysenteriae 1 have been believed to be chromosomally encoded and not transmissible. we ... | 1999 | 10594830 |
| central nervous system manifestations of childhood shigellosis: prevalence, risk factors, and outcome. | alterations in consciousness, including seizures, delirium, and coma, are known to occur during shigella infection. previous reports have suggested that febrile convulsions and altered consciousness are more common during shigellosis than with other childhood infections. those reports, however, have been from locations where s dysenteriae type 1 was not common, thus making it difficult to assess the specific contribution that s dysenteriae type 1 infection, and shiga toxin, might make to the pat ... | 1999 | 9925864 |
| protein conjugates of synthetic saccharides elicit higher levels of serum igg lipopolysaccharide antibodies in mice than do those of the o-specific polysaccharide from shigella dysenteriae type 1. | our development of vaccines to prevent shigellosis is based on the hypothesis that a critical (protective) level of serum igg to the o-specific polysaccharide (o-sp) domain of shigella lipopolysaccharide (lps) confers immunity. the o-sp is a hapten and must be conjugated to a protein to induce serum antibodies. the o-sp of shigella dysenteriae type 1 (approximately 27 tetrasaccharide repeat units), prepared by acid hydrolysis of the lps, was bound to human serum albumin (hsa) by multiple point a ... | 1999 | 10220442 |
| an epidemic of bloody diarrhea: escherichia coli o157 emerging in cameroon? | between november 1997 and april 20, 1998, bloody diarrhea sickened 298 persons in cameroon. laboratory investigation of the epidemic (case-fatality rate, 16.4%) documented amoebiasis in one of three patients and three types of pathogens: multidrug-resistant shigella dysenteriae type 1, s. boydii, and enterohemorrhagic escherichia coli. we report the first isolation of e. coli o157:h7 in cameroon and the second series of cases in the central african region. | 1999 | 10221885 |
| molecular characterization of the shv-11 beta-lactamase of shigella dysenteriae. | a beta-lactamase with an m(r) of 29,000 and a pi of 7.6 was partially purified from a clinical isolate of shigella dysenteriae. the bla gene encoded the shv-11 enzyme carrying the substitution leu-->gln at position 35 and was linked to a strong promoter. this variant, unlike the prototype shv-1 enzyme, hydrolyzed oxacillin, cloxacillin, and oxyiminocephalosporins such as cefotaxime. | 1999 | 10428943 |
| evaluation of pulsed-field gel electrophoresis for typing of shigella dysenteriae type 1. | pulsed-field gel electrophoresis (pfge) has been used successfully to discriminate between strains of many different bacterial species. in this study, digestion of bacterial dna with the restriction endonuclease noti and pfge were evaluated for the typing of isolates of shigella dysenteriae type 1, an important cause of epidemic dysentery. there were 27 isolates from four outbreaks of dysentery, and 44 isolates from endemic dysentery cases and a laboratory culture collection. the epidemic isolat ... | 1999 | 10451002 |
| [contribution of divalent cations to the maintenance of membrane potentials in the oocytes of pleurodeles waltlii michah (amphibia, urodela)]. | when the external concentration of ca and mg is changed, the oocyte membrane potential, in the urodela amphibian: pleurodeles waltlii, is not significantly modified. the addition of chelator agents, egta and edta in ca, mg free steinberg solution promotes a membrane depolarisation and the rise of membrane conductance. it is concluded that divalent ions ca++ and mg++ are needed to maintain a potential difference between internal and external medium of the oocyte. | 1999 | 96993 |
| how many specialists? | the need for specialists cannot be adequately assessed on the basis of current practice and an estimated case-load (based on prevalence/population ratio). specialists should declare which patients can or cannot be expected to benefit from their treatment, and they should consider the consequences of underprovision of specialist services. specialists should also decide how much of what they normally do might equally well be carried out by generalists using the knowledge of specialists. only then ... | 1999 | 85176 |
| [evaluation of the effectiveness of vick vaporub ointment measured by improvement in the drinking ability of infants suffering from a cold]. | 1999 | 84443 | |
| severe hypomagnesemia associated with pentamidine therapy. | a case of severe hypomagnesemia in a patient with aids that manifested as changes in mental status is presented. the hypomagnesemia was due to renal wasting of magnesium, most probably caused by pentamidine-induced renal tubular injury. this entity has been reported once before and should be considered in the differential diagnosis of altered mental status in patients with aids. | 1999 | 1866558 |
| [nurse's functions in the surgical treatment room]. | 1999 | 91077 | |
| home observation for measurement of the environment: a revision of the preschool scale. | information pertaining to a revision of the caldwell home inventory for use with families of children ages 3 to 6 was presented. factor and item analyses were used as a basis for reducing the number of items from 80 to 55. the items were clustered into eight subscales. kuder-richardson 20 coefficients for the scale ranged from .53 to .93. concurrent and predictive validity studies indicated that the home scales significantly correlated with iq (as high as r = .58). low to moderate correlations w ... | 1999 | 93417 |
| urine glucose measurement in the management of diabetes mellitus. | 1999 | 97043 | |
| [parenteral nutrition in acute uremia in the surgical patient]. | 1999 | 96386 | |
| manometry in the evaluation of esophageal function. | 1999 | 99711 | |
| [congenital glaucoma in hurler's syndrome and in lowe's syndrome. clinical and electron microscopy findings]. | 2 cases of congenital glaucoma combined with a general metabolic disease are described. 1 patient displayed the symptoms of a mucopolysaccharidosis (hurler's syndrome), the other patient showed the characteristics of lowe's oculo-cerebrorenal syndrome. in both patients a surgical trabeculectomy was performed. the excised tissues were analysed by electron microscopy. distinct vacuolar or fibrillar deposits were observed in both cases in the trabecular region and in schlemm's canal. possibly, thes ... | 1999 | 96681 |
| excessive pressure for respiratory therapy. | 1999 | 116529 | |
| [evaluation of blood-liquor barrier by protein gradients in congenital hydrocephalus in infancy]. | 1999 | 88669 | |
| [pituitary reserve of thyrotrophic hormone in hypothyroid children]. | 1999 | 103634 | |
| amylase/creatinine clearance ratio and tubular proteinuria in acute pancreatitis. | amylase/creatinine clearance ratio (cam/ccr), urinary protein concentration and urinary protein pattern were studied in 102 samples from 27 patients with acute pancreatitis and in 46 controls. raised cam/ccr, proteinuria and a tubular protein pattern were present in 74, 56 and 96% of the patients, respectively. however, cam/ccr and proteinuria and cam/ccr and tubular protein pattern were not correlated. these results do not support the suggestion that an elevated cam/ccr in acute pancreatitis is ... | 1999 | 94020 |
| hyperosmolar hyperglycemic non-ketotic syndrome treated without insulin: case reports. | 1999 | 99698 | |
| comparison between hla-d (lcl) and dr typing. | 1999 | 93807 | |
| the psychological problems of the deaf and blind. | 1999 | 91198 | |
| effects of x-rays on the chloroplasts of acetabularia mediterranea [proceedings]. | 1999 | 93929 | |
| grandmother's poisoned well: report of a case of methemoglobinemia in an infant in oklahoma. | 1999 | 4688467 | |
| who should measure the blood-pressure? | 1999 | 84917 | |
| to reuse or reconstruct: that is the question. | with cost containment being a vital concern, health care facilities must carefully assess differences in the cost between new construction and renovation. | 1999 | 103799 |
| [proton beam treatment in the neurosurgical field]. | 1999 | 96847 | |
| short-course chemotherapy for tuberculosis. | 1999 | 89476 | |
| substrate specificity of hexosaminidase a isolated from the liver of a patient with a rare form (ab variant) of infantile gm2 gangliosidosis and control tissues. | 1999 | 96668 | |
| [esophago-jejunostomy at the level of the neck for restoration of continuity in carcinoma of the esophagus (after esophageal resection or for palliative reasons) (author's transl)]. | a technic of esophago-jejunostomy in the neck is described which uses a y loop, to which is given a further blood supply through the internal mammary vessels, united to the vessels of the transplanted loop through microsurgical anastomoses. this technic is used either for purely palliative reasons or when the esophageal tumour has become inoperable, or after esophagectomy as a procedure for reconstruction of the digestive tract. | 1999 | 89117 |
| thyrotoxicosis during pregnancy. | the diagnosis of thyrotoxicosis during pregnancy is difficult on clinical grounds only. the determination of free thyroid hormones or free thyroid hormone indices is important and is possibly supplemented by the trh stimulation test. thyrotoxicosis during pregnancy should always be treated actively. the authors recommend subtotal thyroidectomy if there are indications for surgical therapy (nodular goitre or large diffuse goitre). otherwise treatment with thyrostatic agents is used. after operati ... | 1999 | 84547 |
| [availability of the measurement of plasma beta-thromboglobulin (beta-tg) for cerebrovascular diseases (author's transl)]. | 1999 | 93482 | |
| erythrocyte sodium/potassium fluxes in hypertension. | 1999 | 85891 | |
| ephraim michael bluestone. | 1999 | 89496 | |
| vitamins in intravenous feeding: a study of water-soluble vitamins and folate in critically ill patients receiving intravenous nutrition. | red cell b vitamins, folate and white cell vitamin c were measured in a group of critically ill surgical patients before and following a course of intravenous nutrition. patients received a widely used vitamin supplementation regimen in the form of one ampoule of water-soluble vitamins daily and recommended doses of intramuscular folate, vitamin b12 and vitamin k weekly. this regimen was adequate to maintain tissue levels of the water-soluble vitamins and folate. patients with initially low valu ... | 1999 | 96904 |
| primary aldosteronism: a noninvasive procedure for tumor localization as well as for distinction from bilateral hyperplasia. | 1999 | 96670 | |
| [associated congenital pulmonary stenosis and aortic stenosis. apropos of 5 cases]. | 1999 | 96770 | |
| [risk factors in mitral valve replacements]. | the authors report 137 isolated mitral valve replacements carried out between 1966 and 1975, with an operative mortality of 13.1%. certain risk factors are demonstrable:--from the clinical point of view: previous cardiac surgery, 3 or more attacks of cardiac failure, a prolonged preoperatives course, atrial fibrillation, and cardiomegaly on the x ray. the combination of these risk factors is very serious as when three or more risk factors are operative at the same time, the mortality is 40%. red ... | 1999 | 407857 |
| fine-needle aspiration cytology. | 1999 | 89365 | |
| applied teaching concepts of animated motion slides in otolaryngology. | motion is an essential part of otolaryngologic function, and an understanding of concepts of motion is critical in teaching otolaryngology. standard movie projection devices have intrinsic defects, such as considerable expense to make, complexity of operation, and a lack of flexibility. slide projection transparencies (2x2) offer instructional flexibility but could not be used to project motion until recently. using applications of gelatin films of images with polarizing light, we have been able ... | 1999 | 91151 |
| abducens palsy after lumbar myelography with watersoluble contrast media. | five patients who developed abducens palsy after myelography with watersoluble contrast media are reported. these palsies can be compared to abducens palsies after spinal anesthesia and diagnostic lumbar puncture. they are most likely due to the lumbar puncture. the arguments for this explanation are discussed. the experience with these five patients suggests a greater incidence of postpuncture abducens palsy after myelography with watersoluble contrast media than after spinal anesthesia or lumb ... | 1999 | 84865 |
| [hyperthyroidism and hypothyroidism in general practice. diagnosis and therapy]. | 1999 | 84446 | |
| diffuse cutaneous mastocytosis: a report of neonatal onset. | a child developed diffuse cutaneous mastocytosis when 20 days old. his prognosis appears good, compared with other reports of similar neonatal onset. | 1999 | 94218 |
| [renewal of noradrenaline in different zones of the central nervous system of inbred mice strains and their recombinants]. | a good correlation exists between the learning capacity and norepinephrine metabolism in the neocortex of c57 and balb inbred mice strains, as well as their f1 hybrids and seven recombinant inbred strains derived from their cross. the animals with a better learning performance are characterised by low levels of norepinephrine, as well as a slow metabolic rate of this neurotransmitter in the cortex. such a correlation has not been found to exist in the other cerebral regions studied. | 1999 | 96976 |
| transport of oxygen and carbon dioxide by hemoglobin-saline solution in the red cell free primate. | 1999 | 96451 | |
| captopril in a hyponatraemic hypertensive: need for caution in initiating therapy. | 1999 | 85145 | |
| [structuro-functional analysis of identified grape snail neurons]. | the study of microanatomy of central neurons in helix pomatia showed that each identified neurone has a constant number of definitely directed processes. the branching pattern of the processes is also specific for each neurone, but in the same cell the number of the branches may vary. it is concluded, that the general morphology of the neurone is its sufficiently stable characteristic and may serve as a criterion for its identification. the possible functional role of different types of the neur ... | 1999 | 93832 |
| antimicrobial effects of psidium guajava extract as one mechanism of its antidiarrhoeal action. | a morphine-like spasmolytic action (not naloxone reversible; involving the inhibition of acetylcholine release) and also effects on the transmural transport of electrolytes (na(+) and k(+)) and water have been reported as possible modes of the antidiarrhoeal action of polar fractions of psidium guajava leaf extractives. the objective for this study was to verify if the reported modes of the antidiarrhoeal action should be broadened to include direct antimicrobial actions on some of the more comm ... | 1999 | 22589684 |
| radix puerariae in migraine. | 1998 | 108058 | |
| fetal heart rate during a maternal grand mal epileptic seizure. | although maternal ingestion of antiepileptic drugs is strongly suspected of causing congenital defects, particularly oral clefts, the effect of epilepsy itself or a combined effect of drug intake and epilepsy have not been excluded as etiological factors. very little is known about fetal oxygenation during a maternal grand mal epileptic seizure. we describe two cases in which fetal heart rate was recorded during a maternal epileptic seizure during labor. the first fetus became clearly asphyctic ... | 1998 | 106102 |
| haloperidol treatment of a sixty-year narcotic addiction: case report. | 1998 | 108622 | |
| antibiotic usage surveillance: an overview of the issues. | 1998 | 121379 | |
| gene complementation in the t-lymphocyte proliferative response to poly (glu55lys36phe9)n. a demonstration that both immune response gene products must be expressed in the same antigen-presenting cell. | the immune response (ir) to the random copolymer glphi depends upon the function of two ir genes, ir-glphi-beta[beta] and ir-glphi-alpha[alpha], mapped to the i-a and i-e/c subregions of the major histocompatibility complex, respectively. in this paper, the site(s) of expression of the products of these two ir genes was examined by evaluating t-lymphocyte proliferative responses of bone marrow radiation chimeras. chimeras were created in [alpha+beta- x alpha-beta+]f1 responder mice by lethal irr ... | 1998 | 105077 |
| long-term survival in multiple myeloma. | 1998 | 98920 | |
| [feeding of patients following total laryngectomy]. | 1998 | 108651 | |
| platelet function and occlusive vascular disease in diabetes mellitus. | 1998 | 106136 | |
| ["masked" supra-renal tumour (author's transl)]. | for the diagnosis of supra-renal tumours or tumours of supra-renal rests, it is necessary to employ all available radiological methods as well as the clinical data. two cases are described in which a supra-renal tumour had been "masked" and found at operation. in the first case a cyst in the tail of the pancreas had been considered, in the second, a tumour of the renal hilum or ureter had been diagnosed. it is concluded that in the differential diagnosis of a cyst of the tail of the pancreas, su ... | 1998 | 124685 |
| [irresponsible quarrel concerning mammography guidelines]. | 1998 | 108541 | |
| the genetic toxicology of phenoxy acids other than 2,4,5-t. | 1998 | 107443 |