Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| contribution of lysinibacillus sphaericus hemolysin and chitin-binding protein in entomopathogenic activity against insecticide resistant aedes aegypti. | given its toxicity against culicid larvae, lysinibacillus sphaericus is used for the biological control of mosquitoes such as culex sp. and anopheles sp. the toxicity factors currently reported for l. sphaericus include the binary toxin, mtx toxins, and the s-layer. however, aedes aegypti is refractory to the binary toxin, the most toxic larvicidal protein of l. sphaericus. until now, there are no evidences of the hemolytic and chitinolytic capacity of l. sphaericus. herein, the expression of th ... | 2017 | 28940156 |
| molecular typing and phylogeny of wolbachia: a study from assam, north-eastern part of india. | wolbachia are maternally inherited endosymbiotic alphaproteobacteria, infecting 40-75% of arthropod species. knowledge on distribution of native strains infecting mosquito vectors from endemic regions is essential for successful implementation of vector control interventions utilizing potential strains of wolbachia. study identified various native strains of wolbachia inhabiting different mosquito species from field and colonised conditions of assam. the fly drosophila melanogaster was also incl ... | 2017 | 28939497 |
| the dengue preface to endemic in mainland china: the historical largest outbreak by aedes albopictus in guangzhou, 2014. | dengue was regarded as a mild epidemic in mainland china transmitted by aedes albopictus. however, the 2014 record-breaking outbreak in guangzhou could change the situation. in order to provide an early warning of epidemic trends and provide evidence for prevention and control strategies, we seek to characterize the 2014 outbreak through application of detailed cases and entomological data, as well as phylogenetic analysis of viral envelope (e) gene. | 2017 | 28934991 |
| isolation and identification of xenorhabdus and photorhabdus bacteria associated with entomopathogenic nematodes and their larvicidal activity against aedes aegypti. | aedes aegypti is a potential vector of west nile, japanese encephalitis, chikungunya, dengue and zika viruses. alternative control measurements of the vector are needed to overcome the problems of environmental contamination and chemical resistance. xenorhabdus and photorhabdus are symbionts in the intestine of entomopathogenic nematodes (epns) steinernema spp. and heterorhabditis spp. these bacteria are able to produce a broad range of bioactive compounds including antimicrobial, antiparasitic, ... | 2017 | 28934970 |
| proteomics technique opens new frontiers in mobilome research. | a large proportion of the genome of most eukaryotic organisms consists of highly repetitive mobile genetic elements. the sum of these elements is called the "mobilome," which in eukaryotes is made up mostly of transposons. transposable elements contribute to disease, evolution, and normal physiology by mediating genetic rearrangement, and through the "domestication" of transposon proteins for cellular functions. although 'omics studies of mobilome genomes and transcriptomes are common, technical ... | 2017 | 28932623 |
| zika virus congenital syndrome: experimental models and clinical aspects. | viral infections have long been the cause of severe diseases to humans, increasing morbidity and mortality rates worldwide, either in rich or poor countries. yellow fever virus, h1n1 virus, hiv, dengue virus, hepatitis b and c are well known threats to human health, being responsible for many million deaths annually, associated to a huge economic and social cost. in this context, a recently introduced flavivirus in south america, called zika virus (zikv), led the who to declare in february 1st 2 ... | 2017 | 28932235 |
| ph control in the midgut of aedesaegypti under different nutritional conditions. | aedes aegypti is one of the most important disease vectors in the world. because their gut is the first site of interaction with pathogens, it is important to understand a. aegypti gut physiology. in this study, we investigated the mechanisms of ph control in the midgut of a. aegypti females under different nutritional conditions. we found that unfed females have an acidic midgut (ph ∼6). the midgut of unfed insects is actively maintained at ph 6 regardless of the ingestion of either alkaline or ... | 2017 | 28931720 |
| microgeographic population structuring of aedes aegypti (diptera: culicidae). | aedes aegypti is one of the species most favored by changes in the environment caused by urbanization. its abundance increases rapidly in the face of such changes, increasing the risk of disease transmission. previous studies have shown that mosquito species that have adapted to anthropogenic environmental changes benefit from urbanization and undergo population expansion. in light of this, we used microsatellite markers to explore how urbanization processes may be modulating ae. aegypti populat ... | 2017 | 28931078 |
| pyrethroid resistance alters the blood-feeding behavior in puerto rican aedes aegypti mosquitoes exposed to treated fabric. | emerging insecticide resistance is a major issue for vector control. it decreases the effectiveness of insecticides, thereby requiring greater quantities for comparable control with a net increase in risk of disease resurgence, product cost, and damage risk to the ecosystem. pyrethroid resistance has been documented in puerto rican populations of aedes aegypti (l.) mosquitoes. in this study, topical toxicity of five insecticides (permethrin, etofenprox, deltamethrin, ddt, transfluthrin) was dete ... | 2017 | 28931018 |
| emerging arboviruses in rio grande do sul, brazil: chikungunya and zika outbreaks, 2014-2016. | the recent emergence of arboviruses such as chikungunya virus (chikv) and zika virus (zikv) in brazil has posed a threat to human health and to the country's economy. outbreaks occur mainly in tropical areas; however, increasing number of cases have been observed in rio grande do sul (rs), the southernmost state; therefore, surveillance of these arboviruses is essential for public health measures. | 2017 | 28929534 |
| sybr green-based one step quantitative real-time polymerase chain reaction assay for the detection of zika virus in field-caught mosquitoes. | the monitoring of vectors is one of the key surveillance measures to assess the risk of arbovirus transmission and the success of control strategies in endemic regions. the recent re-emergence of zika virus (zikv) in the tropics, including singapore, emphasizes the need to develop cost-effective, rapid and accurate assays to monitor the virus spread by mosquitoes. as zikv infections largely remain asymptomatic, early detection of zikv in the field-caught mosquitoes enables timely implementation ... | 2017 | 28927458 |
| insecticide susceptibility of aedes albopictus and ae. aegypti from brazil and the swiss-italian border region. | aedes aegypti and ae. albopictus are two highly invasive mosquito species, both vectors of several viruses, including dengue, chikungunya and zika. while ae. aegypti is the primary vector in the tropics and sub-tropics, ae. albopictus is increasingly under the public health watch as it has been implicated in arbovirus-transmission in more temperate regions, including continental europe. vector control using insecticides is the pillar of most control programmes; hence development of insecticide r ... | 2017 | 28927441 |
| community participation in mosquito breeding site control: an interdisciplinary mixed methods study in curaçao. | as the arboviral diseases dengue, chikungunya and zika emerge in the americas, so does the need for sustainable vector control policies. to successfully achieve mosquito control, joint efforts of both communities and governments are essential. this study investigates this important, but by-and-large neglected topic. | 2017 | 28927437 |
| differential expression of putative sodium-dependent cation-chloride cotransporters in aedes aegypti. | the yellow fever mosquito, aedes aegypti, has three genes that code for proteins with sequence similarity to vertebrate na+-k+-cl- cotransporters (nkccs) of the solute-linked carrier 12 superfamily of cation-chloride cotransporters (cccs). we hypothesized that these mosquito nkcc orthologues have diverged to perform distinct roles in salt secretion and absorption. in phylogenetic analyses, one protein (aenkcc1) groups with a drosophila melanogaster nkcc that mediates salt secretion whereas two o ... | 2017 | 28923771 |
| role of the venus kinase receptor in the female reproductive physiology of the desert locust, schistocerca gregaria. | venus kinase receptors (vkr) are a subfamily of invertebrate receptor tyrosine kinases, which have only recently been discovered. they contain an intracellular tyrosine kinase domain and an extracellular venus flytrap domain. vkrs have been functionally and pharmacologically characterized in only two invertebrate species, namely the human parasite schistosoma mansoni and the mosquito aedes aegypti, where they play a crucial role in oogenesis. here, we report the characterization of a vkr in the ... | 2017 | 28916758 |
| duplex real-time pcr assay distinguishes aedes aegypti from ae. albopictus (diptera: culicidae) using dna from sonicated first-instar larvae. | aedes aegypti (l.) and ae. albopictus (skuse) are important arbovirus vectors in the united states, and the recent emergence of zika virus disease as a public health concern in the americas has reinforced a need for tools to rapidly distinguish between these species in collections made by vector control agencies. we developed a duplex real-time pcr assay that detects both species and does not cross-amplify in any of the other seven aedes species tested. the lower limit of detection for our assay ... | 2017 | 28981691 |
| pyrethroid susceptibility has been maintained in the dengue vector, aedes aegypti (diptera: culicidae), in queensland, australia. | although pesticide resistance is common in insect vectors of human diseases, the evolution of resistance might be delayed if management practices are adopted that limit selection of resistance alleles. outbreaks of dengue fever have occurred in queensland, australia, since the late 1800s, leading to ongoing attempts to control the mosquito vector, aedes aegypti (l.). since the 1990s, pyrethroid insecticides have been used for this purpose, but have been applied in a strategic manner with a varie ... | 2017 | 28981684 |
| resistance status and resistance mechanisms in a strain of aedes aegypti (diptera: culicidae) from puerto rico. | puerto rico (pr) has a long history of vector-borne disease and insecticide-resistant aedes aegypti (l.). defining contributing mechanisms behind phenotypic resistance is critical for effective vector control intervention. however, previous studies from pr have each focused on only one mechanism of pyrethroid resistance. this study examines the contribution of p450-mediated enzymatic detoxification and sodium channel target site changes to the overall resistance phenotype of ae. aegypti collecte ... | 2017 | 28981681 |
| cutaneous manifestations of chikungunya fever: observations from an outbreak at a tertiary care hospital in southeast rajasthan, india. | chikungunya fever is caused by chikungunya virus which is transmitted by the bite of infected aedes aegypti and a. albopictus mosquitoes. | 2017 | 28979866 |
| infection rate of aedes aegypti mosquitoes with dengue virus depends on the interaction between temperature and mosquito genotype. | dengue fever is the most prevalent arthropod-transmitted viral disease worldwide, with endemic transmission restricted to tropical and subtropical regions of different temperature profiles. temperature is epidemiologically relevant because it affects dengue infection rates in aedes aegypti mosquitoes, the major vector of the dengue virus (denv). aedes aegypti populations are also known to vary in competence for different denv genotypes. we assessed the effects of mosquito and virus genotype on d ... | 2017 | 28978730 |
| identification of surveillance and control priority areas for dengue and other arboviruses transmitted by aedes aegypti in natal-rn, brazil: experience report. | to report the vigi@dengue experience, held in the municipality of natal-rn, brazil, from october/2015 to may/2016. | 2017 | 28977187 |
| circulation of denv2 and denv4 in aedes aegypti (diptera: culicidae) mosquitoes from praia, santiago island, cabo verde. | arthropod-borne viruses, such as dengue (denv), chikungunya (chikv), and zika (zikv), pose a challenge to public health, due to their worldwide distribution and large-scale outbreaks. dengue fever is currently one of the most important diseases and it is caused by four serotypes of denv and is mainly transmitted by the mosquito aedes aegypti. it is estimated that 50-100 million cases are reported every year worldwide. more recently, chikv and zikv, which are also transmitted by ae. aegypti, have ... | 2017 | 28973490 |
| modeling the environmental suitability for aedes (stegomyia) aegypti and aedes (stegomyia) albopictus (diptera: culicidae) in the contiguous united states. | the mosquitoes aedes (stegomyia) aegypti (l.)(diptera:culicidae) and ae. (stegomyia) albopictus (skuse) (diptera:culicidae) transmit dengue, chikungunya, and zika viruses and represent a growing public health threat in parts of the united states where they are established. to complement existing mosquito presence records based on discontinuous, non-systematic surveillance efforts, we developed county-scale environmental suitability maps for both species using maximum entropy modeling to fit clim ... | 2017 | 29029153 |
| combined toxicity of three essential oils against aedes aegypti (diptera: culicidae) larvae. | essential oils are potential alternatives to synthetic insecticides because they have low mammalian toxicity, degrade rapidly in the environment, and possess complex mixtures of bioactive constituents with multi-modal activity against the target insect populations. twenty-one essential oils were initially screened for their toxicity against aedes aegypti (l.) larvae and three out of the seven most toxic essential oils (manuka, oregano, and clove bud essential oils) were examined for their chemic ... | 2017 | 29029151 |
| effect of climatic conditions and water bodies on population dynamics of the dengue vector, aedes aegypti (diptera: culicidae). | the population of mosquitoes is mainly influenced by the biotic and abiotic factors. although aedes aegypti was reported until 1960's in the punjab, pakistan, the population has increased dramatically since 2009 and caused severe epidemics in 2011 due to heavy floods and rains. thus, this study was carried out to know the effect of biotic and abiotic factors on the population of aedes aegypti. | 2017 | 29026852 |
| central nervous system effects of intrauterine zika virus infection: a pictorial review. | relatively few agents have been associated with congenital infections involving the brain. one such agent is the zika virus, which has caused several outbreaks worldwide and has spread in the americas since 2015. the zika virus is an arbovirus transmitted by infected female mosquito vectors, such as the aedes aegypti mosquito. this virus has been commonly associated with congenital infections of the central nervous system and has greatly increased the rates of microcephaly. ultrasonography (us) ... | 2017 | 29019762 |
| a multiplex pcr for detection of knockdown resistance mutations, v1016g and f1534c, in pyrethroid-resistant aedes aegypti. | mutation of the voltage-gated sodium channel (vgsc) gene, or knockdown resistance (kdr) gene, is an important resistance mechanism of the dengue vector aedes aegypti mosquitoes against pyrethroids. in many countries in asia, a valine to glycine substitution (v1016g) and a phenylalanine to cysteine substitution (f1534c) are common in ae. aegypti populations. the g1016 and c1534 allele frequencies have been increasing in recent years, and hence there is a need to have a simple and inexpensive tool ... | 2017 | 29017613 |
| temporal distribution and insecticide resistance profile of two major arbovirus vectors aedes aegypti and aedes albopictus in yaoundé, the capital city of cameroon. | aedes aegypti and ae. albopictus are the major epidemic vectors of several arbovirus diseases such as yellow fever, dengue, zika and chikungunya worldwide. both aedes vectors are presents in cameroon; however, knowledge on the dynamic of the distribution of these species across cities and their resistance profile to insecticide are limited. here, we assessed the current distribution of ae. aegypti and ae. albopictus in yaoundé, the capital city, established the resistance profile to insecticides ... | 2017 | 29017606 |
| hydrogen peroxide resistance in strigomonas culicis: effects on mitochondrial functionality and aedes aegypti interaction. | reactive oxygen species (ros) are toxic molecules involved in several biological processes such as cellular signaling, proliferation, differentiation and cell death. adaptations to oxidative environments are crucial for the success of the colonization of insects by protozoa. strigomonas culicis is a monoxenic trypanosomatid found in the midgut of mosquitoes and presenting a life cycle restricted to the epimastigote form. among s. culicis peculiarities, there is an endosymbiotic bacterium in the ... | 2017 | 28993269 |
| evaluation of gamma radiation-induced dna damage in aedes aegypti using the comet assay. | the study was undertaken to evaluate gamma radiation-induced dna damage in aedes aegypti. the comet assay was employed to demonstrate the extent of dna damage produced in adult male a. aegypti exposed to seven different doses of gamma radiation, ranging from 1 gy to 50 gy. dna damage was measured as the percentage of comet tail dna. a significant linear increase in dna damage was observed in all samples; the extent of damage being proportional to the dose of gamma radiation the organism received ... | 2017 | 28992792 |
| how does competition among wild type mosquitoes influence the performance of aedes aegypti and dissemination of wolbachia pipientis? | wolbachia has been deployed in several countries to reduce transmission of dengue, zika and chikungunya viruses. during releases, wolbachia-infected females are likely to lay their eggs in local available breeding sites, which might already be colonized by local aedes sp. mosquitoes. therefore, there is an urgent need to estimate the deleterious effects of intra and interspecific larval competition on mosquito life history traits, especially on the duration of larval development time, larval mor ... | 2017 | 28991902 |
| characterization of the zika virus induced small rna response in aedes aegypti cells. | rna interference (rnai) controls arbovirus infections in mosquitoes. two different rnai pathways are involved in antiviral responses: the piwi-interacting rna (pirna) and exogenous short interfering rna (exo-sirna) pathways, which are characterized by the production of virus-derived small rnas of 25-29 and 21 nucleotides, respectively. the exo-sirna pathway is considered to be the key mosquito antiviral response mechanism. in aedes aegypti-derived cells, zika virus (zikv)-specific sirnas were pr ... | 2017 | 29040304 |
| patchy dna forms of the zika virus rna genome are generated following infection in mosquito cell cultures and in mosquitoes. | zika virus (zikv) is a mosquito-borne flavivirus and has historically been reported to cause mild symptomatic diseases during human infections. more recently, the explosion of microcephaly among infants born to zikv-infected women has made zikv a global public health concern. while zikv causes acute human diseases, infections of vector mosquitoes are basically non-pathogenic, allowing persistent infections and conferring lifelong ability to transmit the virus. recent studies have revealed that d ... | 2017 | 29039731 |
| lure-and-kill yeast interfering rna larvicides targeting neural genes in the human disease vector mosquito aedes aegypti. | new mosquito control strategies are vitally needed to address established arthropod-borne infectious diseases such as dengue and yellow fever and emerging diseases such as zika and chikungunya, all of which are transmitted by the disease vector mosquito aedes aegypti. in this investigation, saccharomyces cerevisiae (baker's yeast) was engineered to produce short hairpin rnas (shrnas) corresponding to the aedes aegypti orthologs of fasciculation and elongation protein zeta 2 (fez2) and leukocyte ... | 2017 | 29038510 |
| using phage display technology to obtain crybodies active against non-target insects. | the insecticidal cry toxins produced by bacillus thuringiensis (bt) are increasingly important in the biological control of insect pests and vectors of human disease. markets for bt products and transgenic plants expressing their toxins are driven by their specificity, safety and the move away from chemical control agents. however, the high specificity of cry toxins can also prove to be a limitation when there is no known cry toxin active against a particular target. novel activities can be disc ... | 2017 | 29097681 |
| efficiency of two larval diets for mass-rearing of the mosquito aedes aegypti. | aedes aegypti is a major vector of arboviruses that may be controlled on an area-wide basis using the sterile insect technique (sit). larval diet is a major factor in mass-rearing for sit programs. we compared dietary effects on immature development and adult fitness-related characteristics for an international atomic energy agency (iaea) diet, developed for rearing ae. albopictus, and a standardized laboratory rodent diet (lrd), under a 14:10 h (light:dark) photoperiod ("light" treatment) or co ... | 2017 | 29095933 |
| insecticide susceptibility screening against culex and aedes (diptera: culicidae) mosquitoes from the united states. | mosquitoes exposed to sublethal doses of insecticides may be selected for resistance to insecticide active ingredients (ais). mosquitoes are exposed to ais through agricultural, public/private mosquito control programs, homeowners, and other sources. hence, mosquito control programs should routinely measure the resistance/susceptibility status of mosquito populations of public health concern. the objectives here were to determine resistance status for six ais used in adult mosquito control in th ... | 2017 | 29186579 |
| functional analysis of glycosylation of zika virus envelope protein. | zika virus (zikv) infection causes devastating congenital abnormities and guillain-barré syndrome. the zikv envelope (e) protein is responsible for viral entry and represents a major determinant for viral pathogenesis. like other flaviviruses, the zikv e protein is glycosylated at amino acid n154. to study the function of e glycosylation, we generated a recombinant n154q zikv that lacks the e glycosylation and analyzed the mutant virus in mammalian and mosquito hosts. in mouse models, the mutant ... | 2017 | 29091758 |
| darker eggs of mosquitoes resist more to dry conditions: melanin enhances serosal cuticle contribution in egg resistance to desiccation in aedes, anopheles and culex vectors. | mosquito vectors lay their white eggs in the aquatic milieu. during early embryogenesis water passes freely through the transparent eggshell, which at this moment is composed of exochorion and endochorion. within two hours the endochorion darkens via melanization but even so eggs shrink and perish if removed from moisture. however, during mid-embryogenesis, cells of the extraembryonic serosa secrete the serosal cuticle, localized right below the endochorion, becoming the third and innermost eggs ... | 2017 | 29084225 |
| assessing the population at risk of zika virus in asia - is the emergency really over? | on november 18, 2016, the who ended its designation of the zika virus (zikv) epidemic as a public health emergency of international concern (pheic). at the same time, zikv transmission continues in asia, with the number of asian countries reporting zika cases increasing over the last 2 years. applying a method that combines epidemiological theory with data on epidemic size and drivers of transmission, we characterised the population at risk of zikv infection from aedes aegypti mosquitoes in 15 c ... | 2017 | 29082009 |
| culex quinquefasciatus mosquitoes do not support replication of zika virus. | the rapid spread of zika virus (zikv) in the americas raised many questions about the role of culex quinquefasciatus mosquitoes in transmission, in addition to the key role played by the vector aedes aegypti. here we analysed the competence of cx. quinquefasciatus (with or without wolbachia endosymbionts) for a zikv isolate. we also examined the induction of rna interference pathways after viral challenge and the production of small virus-derived rnas. we did not observe any infection nor such s ... | 2017 | 29076805 |
| voltage-sensitive sodium channel mutations s989p + v1016g in aedes aegypti confer variable resistance to pyrethroids, ddt and oxadiazines. | aedes aegypti is a vector of several important human pathogens. control efforts rely primarily on pyrethroid insecticides for adult mosquito control, especially during disease outbreaks. a. aegypti has developed resistance nearly everywhere it occurs and insecticides are used. an important mechanism of resistance is due to mutations in the voltage-sensitive sodium channel (vssc) gene. two mutations, in particular, s989p + v1016g, commonly occur together in parts of asia. | 2017 | 29064635 |
| asymmetrical competition between aedes aegypti and culex quinquefasciatus (diptera: culicidae) coexisting in breeding sites. | aedes aegypti and culex quinquefasciatus are mosquito vectors for several tropical diseases that represent a current public health problem. the ecological requirements for each species are different, however, both species show high biological adaptability, which promotes their coexistence in the same breeding sites. the purpose of this study was to assess the effect of larval association between ae. aegypti and cx. quinquefasciatus under different laboratory conditions of food supply and tempera ... | 2017 | 29064390 |
| assessment of the insecticidal activity of afoxolaner against aedes aegypti in dogs treated with nexgard®. | twelve healthy dogs were studied in this parallel group, blinded, randomised, and negative controlled efficacy study. on day -1, the 12 dogs included were ranked within sex in descending order of individual pre-treatment (day -5) fed mosquito counts and randomly allocated by blocks of two dogs to the untreated control group or the afoxolaner-treated group. nexgard® (merial, now part of boehringer ingelheim animal health) was administered orally on day 0 in accordance with the european label inst ... | 2017 | 29063828 |
| synthesis and chemometrics of thymol and carvacrol derivatives as larvicides against aedes aegypti. | thymol and carvacrol have previously demonstrated larvicidal activity against aedes aegypti (diptera: culicidae). in view of this fact, it was of our interest to obtain synthetic derivatives and evaluate their larvicidal activity on ae. aegypti larvae. | 2017 | 29062856 |
| evaluation of larvicidal activity of essential oil from leaves of coccinia grandis against three mosquito species. | to study the chemical constituents and larvicidal activity of essential oil extracted from the leaves of coccinia grandis against three mosquito species. | 2017 | 29062847 |
| use of a recombinant mosquito densovirus as a gene delivery vector for the functional analysis of genes in mosquito larvae. | in vivo microinjection is the most commonly used gene transfer technique for analyzing the gene functions in individual mosquitoes. however, this method requires a more technically demanding operation and involves complicated procedures, especially when used in larvae due to their small size, relatively thin and fragile cuticle, and high mortality, which limit its application. in contrast, viral vectors for gene delivery have been developed to surmount extracellular and intracellular barriers. t ... | 2017 | 29053694 |
| designing ecofriendly bionanocomposite assembly with improved antimicrobial and potent on-site zika virus vector larvicidal activities with its mode of action. | dialyzed natural polymer, fibroin, from bombyx mori was used to synthesize biocompatible silver and gold nanoparticles in-situ in dispersion form. the films of pure fibroin (pf), fibroin-silver nanocomposite (fsnc) and fibroin-gold nanocomposite (fgnc) were fabricated by drop casting method. the characterization of the resultant dispersion and films was performed by visual color change, uv-vis spectroscopy and atomic force microscopy. the dispersions of pf, fsnc and fgnc were tested for antibact ... | 2017 | 29138496 |
| germline cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, aedes aegypti. | the development of crispr/cas9 technologies has dramatically increased the accessibility and efficiency of genome editing in many organisms. in general, in vivo germline expression of cas9 results in substantially higher activity than embryonic injection. however, no transgenic lines expressing cas9 have been developed for the major mosquito disease vector aedes aegypti here, we describe the generation of multiple stable, transgenic ae. aegypti strains expressing cas9 in the germline, resulting ... | 2017 | 29138316 |
| incidence of dengue and chikungunya viruses in mosquitoes and human patients in border provinces of vietnam. | dengue virus remains a major threat in vietnam, while chikungunya virus is expected to become one. surveillance was conducted from 2012 to 2014 in vietnam to assess the presence of dengue and chikungunya viruses in patients hospitalized with acute fever in five vietnam provinces neighboring lao pdr and cambodia. surveillance was extended to mosquitoes present in the vicinity of the patients' households. | 2017 | 29121985 |
| the impact of temperature and wolbachia infection on vector competence of potential dengue vectors aedes aegypti and aedes albopictus in the transmission of dengue virus serotype 1 in southern taiwan. | we evaluated the impact of temperature and wolbachia infection on vector competence of the local aedes aegypti and ae. albopictus populations of southern taiwan in the laboratory. | 2017 | 29116011 |
| assessment of achyranthes aspera induced toxicity and molecular analysis of rapd-pcr profiles of larval genomic dna of aedes aegypti l. (diptera: culicidae). | current studies investigated the anti-mosquito potential of achyranthes aspera against the dengue vector, aedes aegypti. the stems and leaves of a. aspera were extracted in hexane and evaluated for their toxicity against early fourth instars of a. aegypti. the larvicidal efficacy of the extract was validated as per who protocol. the mortality counts were made after 24 h and lc values were calculated at different levels. the adverse impact of extracts was also explored on the larval genomic dna. ... | 2017 | 29114143 |
| a blood meal enhances innexin mrna expression in the midgut, malpighian tubules, and ovaries of the yellow fever mosquito aedes aegypti. | mosquitoes are vectors of pathogens that cause diseases of medical and veterinary importance. female mosquitoes transmit these pathogens while taking a blood meal, which most species require to produce eggs. the period after a blood meal is a time of extreme physiological change that requires rapid coordination of specific tissues. gap junctions (gj) are intercellular channels that aid in the coordination of cells within tissues via the direct transfer of certain small molecules and ions between ... | 2017 | 29113099 |
| aedes aegypti molecular responses to zika virus: modulation of infection by the toll and jak/stat immune pathways and virus host factors. | zika (zikv) and dengue virus (denv) are transmitted to humans by aedes mosquitoes. however, the molecular interactions between the vector and zikv remain largely unexplored. in this work, we further investigated the tropism of zikv in two different aedes aegypti strains and show that the virus infection kinetics, tissue migration, and susceptibility to infection differ between mosquito strains. we also compare the vector transcriptome changes upon zikv or denv infection demonstrating that 40% of ... | 2017 | 29109710 |
| surveillance of intensity level and geographical spreading of dengue outbreak among males and females in punjab, pakistan: a case study of 2011. | dengue fever is viral disease which spreads due to the bite of the aedes aegypti mosquito. in recent years, it has affected around 40% population of the world. its endemic flow has led to a large disease burden, in terms of human and financial resources. | 2017 | 29103928 |
| the diversity, structure, and function of heritable adaptive immunity sequences in the aedes aegypti genome. | the aedes aegypti mosquito transmits arboviruses, including dengue, chikungunya, and zika virus. understanding the mechanisms underlying mosquito immunity could provide new tools to control arbovirus spread. insects exploit two different rnai pathways to combat viral and transposon infection: short interfering rnas (sirnas) and piwi-interacting rnas (pirnas) [1, 2]. endogenous viral elements (eves) are sequences from non-retroviral viruses that are inserted into the mosquito genome and can act a ... | 2017 | 29129531 |
| biosurfactants produced by scheffersomyces stipitis cultured in sugarcane bagasse hydrolysate as new green larvicides for the control of aedes aegypti, a vector of neglected tropical diseases. | biosurfactants are microbial metabolites with possible applications in various industrial sectors that are considered ecofriendly molecules. in recent years, some studies identified these compounds as alternatives for the elimination of vectors of tropical diseases, such as aedes aegypti. the major bottlenecks of biosurfactant industrial production have been the use of conventional raw materials that increase production costs as well as opportunistic or pathogenic bacteria, which restrict the ap ... | 2017 | 29125845 |
| infection of a french population of aedes albopictus and of aedes aegypti (paea strain) with zika virus reveals low transmission rates to these vectors' saliva. | disease caused by the zika virus (zikv) is a public health emergency of international concern. recent epidemics have emerged in different regions of the world and attest to the ability of the virus to spread wherever its vector, aedes species mosquitoes, can be found. we have compared the transmission of zikv by ae. aegypti (paea strain originating from tahiti) and by a french population of ae. albopictus to better assess their competence and the potential risk of the emergence of zikv in europe ... | 2017 | 29125545 |
| evaluation of sticky traps for adult aedes mosquitoes in malaysia: a potential monitoring and surveillance tool for the efficacy of control strategies. | the present study compared the performance of sticky traps in order to identify the most effective and practical trap for capturing aedes aegypti and aedes albopictus mosquitoes. three phases were conducted in the study, with phase 1 evaluating the five prototypes (models a, b, c, d, and e) of sticky trap release-and-recapture using two groups of mosquito release numbers (five and 50) that were released in each replicate. similarly, phase 2 compared the performance between model e and the classi ... | 2017 | 29125255 |
| the distribution of mosquitoes across an altitudinal gradient in the galapagos islands. | an avian malaria parasite (genus plasmodium) has been detected consistently in the galapagos penguin (spheniscus mendiculus) and less frequently in some passerines. we sampled three resident mosquito species (aedes taeniorhynchus, culex quinquefasciatus, and aedes aegypti) using cdc light and gravid traps on three islands in 2012, 2013, and 2014. we sampled along altitudinal gradients to ask whether there are mosquito-free refugia at higher elevations as there are in hawaii. we captured both ae. ... | 2017 | 29125252 |
| ecological characterization of aedes aegypti larval habitats (diptera: culicidae) in artificial water containers in girardot, colombia. | the establishment of habitats for immature ae. aegypti is regulated by biotic and abiotic factors and interactions between these factors. this study aimed to determine the effects of physico-chemical variables and planktonic algae on immature ae. aegypti habitats in 101 water tanks (50 of them containing ae. aegypti pupae and/or larvae) in girardot, colombia. physical data were collected from the water tanks (volume, capacity, material, detritus, and location), along with the physico-chemical va ... | 2017 | 29125250 |
| first record of aedes aegypti and aedes albopictus in thirteen panhandle region counties of texas, u.s.a. | 2017 | 29125249 | |
| laboratory evaluation of a novel lethal ovitrap for control of aedes aegypti. | aedes aegypti (l.) (diptera: culicidae) are known to flourish in a variety of natural and residential habitats and are competent vectors of at least 22 different arboviruses, including dengue, chikungunya, and zika. their global distribution, anthropophilic nature, and vector competency make them species of interest for control. a novel durable dual-action lethal ovitrap (ddalo) with combined larviciding and adulticiding effects, as well as a slow-release polymer (isobutyl methacrylate), was des ... | 2017 | 28968892 |
| comparative efficacy of commercial mosquito coils against aedes aegypti (diptera: culicidae) in malaysia: a nationwide report. | this study was conducted using the glass chamber method to determine the susceptibility status of the dengue vector, aedes aegypti (l.) from 11 states in malaysia to commercial mosquito coils containing four different active ingredients, namely metofluthrin, d-allethrin, d-trans allethrin, and prallethrin. aedes aegypti exhibited various knockdown rates, ranging from 14.44% to 100.00%, 0.00% to 61.67%, 0.00% to 90.00%, and 0.00% to 13.33% for metofluthrin, d-allethrin, d-trans allethrin, and pra ... | 2017 | 29048583 |
| evaluation of embryotoxic and embryostatic effects of the aqueous extract of rhizophora mangle and tannic acid on eggs and larvae of aedes aegypti. | rhizophora mangle is an abundant plant in mangroves and tannic acid is a polyphenol produced by the secondary metabolism of plants. the aim of the study was to evaluate the embryotoxic and embriostatic effects of the aqueous extract of r. mangle and synthetic tannic acid on eggs and larvae of aedes aegypti. a. aegypti eggs were exposed in duplicate at concentrations of 250, 500, 750 and 1000 µg/ml of extract and tannic acid for a period of 14 days. mineral water was used as a negative control. t ... | 2017 | 29044325 |
| full-genome dengue virus sequencing in mosquito saliva shows lack of convergent positive selection during transmission byaedes aegypti. | like other pathogens with high mutation and replication rates, within-host dengue virus (denv) populations evolve during infection of their main mosquito vector,aedes aegypti. within-host denv evolution during transmission provides opportunities for adaptation and emergence of novel virus variants. recent studies of denv genetic diversity failed to detect convergent evolution of adaptive mutations in mosquito tissues such as midgut and salivary glands, suggesting that convergent positive selecti ... | 2017 | 29497564 |
| [zika: probability of establishment of its vector, aedes aegypti, in chile]. | the zika virus has raised world alarm in recent years, representing a major public health problem. in this study we evaluated the potential risk of exposure to zika virus in chile, associated with the probability of establishment of the vector aedes aegypti in the country. niche modelling techniques were used to project the bioclimatic requirements of the vector (global niches), identifying zones of high suitability for the species within the country. then, the potential distribution of the vect ... | 2017 | 29488548 |
| assessment of synthetic floral-based attractants and sugar baits to capture male and female aedes aegypti (diptera: culicidae). | the viruses transmitted by aedes aegypti, including dengue and zika viruses, are rapidly expanding in geographic range and as a threat to public health. in response, control programs are increasingly turning to the use of sterile insect techniques resulting in a need to trap male ae. aegypti to monitor the efficacy of the intervention. however, there is a lack of effective and cheap methods for trapping males. thus, we attempted to exploit the physiological need to obtain energy from sugar feedi ... | 2017 | 28095875 |
| identification of functional enolase genes of the silkworm bombyx mori from public databases with a combination of dry and wet bench processes. | various insect species have been added to genomic databases over the years. thus, researchers can easily obtain online genomic information on invertebrates and insects. however, many incorrectly annotated genes are included in these databases, which can prevent the correct interpretation of subsequent functional analyses. to address this problem, we used a combination of dry and wet bench processes to select functional genes from public databases. | 2017 | 28086791 |
| application of the analytic hierarchy approach to the risk assessment of zika virus disease transmission in guangdong province, china. | an international spread of zika virus (zikv) infection has attracted global attention in 2015. the infection also affected guangdong province, which is located in southern china. multiple factors, including frequent communication with south america and southeast asia, suitable climate (sub-tropical) for the habitat of aedes species, may increase the risk of zikv disease transmission in this region. | 2017 | 28086897 |
| functional characterization of the active mutator-like transposable element, muta1 from the mosquito aedes aegypti. | mutator-like transposable elements (mules) are widespread with members in fungi, plants, and animals. most of the research on the mule superfamily has focused on plant mules where they were discovered and where some are extremely active and have significant impact on genome structure. the maize mudr element has been widely used as a tool for both forward and reverse genetic studies because of its high transposition rate and preference for targeting genic regions. however, despite being widesprea ... | 2017 | 28096902 |
| juvenile hormone biosynthesis in adult blattella germanica requires nuclear receptors seven-up and ftz-f1. | in insects, the transition from juvenile development to the adult stage is controlled by juvenile hormone (jh) synthesized from the corpora allata (ca) glands. whereas a jh-free period during the last juvenile instar triggers metamorphosis and the end of the growth period, the reappearance of this hormone after the imaginal molt marks the onset of reproductive adulthood. despite the importance of such transition, the regulatory mechanism that controls it remains mostly unknown. here, using the h ... | 2017 | 28074850 |
| emergence of epidemic zika virus transmission and congenital zika syndrome: are recently evolved traits to blame? | the mechanisms responsible for the dramatic emergence of zika virus (zikv), accompanied by congenital zika syndrome and guillain-barré syndrome (gbs), remain unclear. however, two hypotheses are prominent: (i) evolution for enhanced urban transmission via adaptation to mosquito vectors, or for enhanced human infection to increase amplification, or (ii) the stochastic introduction of zikv into large, naive human populations in regions with abundant aedes aegypti populations, leading to enough rar ... | 2017 | 28074023 |
| fatty acid synthase 2 contributes to diapause preparation in a beetle by regulating lipid accumulation and stress tolerance genes expression. | diapause, also known as dormancy, is a state of arrested development that allows insects to survive unfavorable environmental conditions. diapause-destined insects store large amounts of fat when preparing for diapause. however, the extent to which these accumulated fat reserves influence diapause remains unclear. to address this question, we investigated the function of fatty acid synthase (fas), which plays a central role in lipid synthesis, in stress tolerance, the duration of diapause prepar ... | 2017 | 28071706 |
| dengue in latin america: systematic review of molecular epidemiological trends. | dengue, the predominant arthropod-borne viral disease affecting humans, is caused by one of four distinct serotypes (denv-1, -2, -3 or -4). a literature analysis and review was undertaken to describe the molecular epidemiological trends in dengue disease and the knowledge generated in specific molecular topics in latin america, including the caribbean islands, from 2000 to 2013 in the context of regional trends in order to identify gaps in molecular epidemiological knowledge and future research ... | 2017 | 28068335 |
| proteomic analysis of cry2aa-binding proteins and their receptor function in spodoptera exigua. | the bacterium bacillus thuringiensis produces crystal (cry) proteins that are toxic to a diverse range of insects. transgenic crops that produce bt cry proteins are grown worldwide because of their improved resistance to insect pests. although bt "pyramid" cotton that produces both cry1a and cry2a is predicted to be more resistant to several lepidopteran pests, including spodoptera exigua, than plants that produce cry1ac alone, the mechanisms responsible for the toxicity of cry2aa in s. exigua a ... | 2017 | 28067269 |
| wolbachia infections in aedes aegypti differ markedly in their response to cyclical heat stress. | aedes aegypti mosquitoes infected with wolbachia bacteria are currently being released for arbovirus suppression around the world. their potential to invade populations and persist will depend on interactions with environmental conditions, particularly as larvae are often exposed to fluctuating and extreme temperatures in the field. we reared ae. aegypti larvae infected with different types of wolbachia (wmel, walbb and wmelpop-cla) under diurnal cyclical temperatures. rearing wmel and wmelpop-c ... | 2017 | 28056065 |
| the dangers of accepting a single diagnosis: case report of concurrent plasmodium knowlesi malaria and dengue infection. | dengue and malaria are two common, mosquito-borne infections, which may lead to mortality if not managed properly. concurrent infections of dengue and malaria are rare due to the different habitats of its vectors and activities of different carrier mosquitoes. the first case reported was in 2005. since then, several concurrent infections have been reported between the dengue virus (denv) and the malaria protozoans, plasmodium falciparum and plasmodium vivax. symptoms of each infection may be mas ... | 2017 | 28049485 |
| pterodon emarginatus oleoresin-based nanoemulsion as a promising tool for culex quinquefasciatus (diptera: culicidae) control. | preparation of nanoformulations using natural products as bioactive substances is considered very promising for innovative larvicidal agents. on this context, oil in water nanoemulsions develop a main role, since they satisfactorily disperse poor-water soluble substances, such as herbal oils, in aqueous media. pterodon emarginatus, popularly known as sucupira, has a promising bioactive oleoresin. however, to our knowledge, no previous studies were carried out to evaluate its potential against cu ... | 2017 | 28049483 |
| insecticidal toxicities of carvacrol and thymol derived from thymus vulgaris lin. against pochazia shantungensis chou &lu., newly recorded pest. | the insecticidal toxicities of five essential oils against pochazia shantungensis adults and nymphs, newly recorded pests, were evaluated. the lc50 values of thymus vulgaris, ruta graveolens, citrus aurantium, leptospermum petersonii and achillea millefolium oils were recorded as 57.48, 84.44, 92.58, 113.26 and 125.78 mg/l, respectively, against p. shantungensis nymphs using the leaf dipping bioassay, and 75.80, 109.86, 113.26, 145.06 and 153.74 mg/l, respectively, against p. shantungensis adult ... | 2017 | 28106093 |
| rna interference mediated knockdown of brugia malayi udp-galactopyranose mutase severely affects parasite viability, embryogenesis and in vivo development of infective larvae. | galactofuranose is an essential cell surface component present in bacteria, fungi and several nematodes such as caenorhabditis spp., brugia spp., onchocerca spp. and strongyloides spp. this sugar maintains the integrity of parasite surface and is essential for virulence. udp-galactopyranose mutase (bmugm) plays a key role in galf biosynthesis by catalyzing conversion of udp-galactopyranose into udp-galactofuranose and knockout studies of the gene in leishmania major, mycobacterium and aspergillu ... | 2017 | 28103957 |
| antiviral effect of compounds derived from the seeds of mammea americana and tabernaemontana cymosa on dengue and chikungunya virus infections. | the transmission of dengue virus (denv) and chikungunya virus (chikv) has increased worldwide, due in part to the lack of a specific antiviral treatment. for this reason, the search for compounds with antiviral potential, either as licensed drugs or in natural products, is a research priority. the objective of this study was to identify some of the compounds that are present in mammea americana (m. americana) and tabernaemontana cymosa (t. cymosa) plants and, subsequently, to evaluate their cyto ... | 2017 | 28100218 |
| microrna-34 directly targets pair-rule genes and cytoskeleton component in the honey bee. | micrornas (mirnas) are key regulators of developmental processes, such as cell fate determination and differentiation. previous studies showed dicer knockdown in honeybee embryos disrupt the processing of functional mature mirnas and impairs embryo patterning. here we investigated the expression profiles of mirnas in honeybee embryogenesis and the role of the highly conserved mir-34-5p in the regulation of genes involved in insect segmentation. a total of 221 mirnas were expressed in honey bee e ... | 2017 | 28098233 |
| the physical genome mapping of anopheles albimanus corrected scaffold misassemblies and identified interarm rearrangements in genus anopheles. | the genome of the neotropical malaria vector anopheles albimanus was sequenced as part of the 16 anopheles genomes project published in 2015. the draft assembly of this species consisted of 204 scaffolds with an n50 scaffold size of 18.1 mb and a total assembly size of 170.5 mb. it was among the smallest genomes with the longest scaffolds in the 16 anopheles species cluster, making an. albimanus the logical choice for anchoring the genome assembly to chromosomes. in this study, we developed a hi ... | 2017 | 27821634 |
| a large scale biorational approach using bacillus thuringiensis israeliensis (strain am65-52) for managing aedes aegypti populations to prevent dengue, chikungunya and zika transmission. | aedes aegypti is a container-inhabiting mosquito and a vector of dengue, chikungunya, and zika viruses. in 2009 several cases of autochthonous dengue transmission were reported in key west, florida, usa prompting a comprehensive response to control a. aegypti. in key west, larvae of this mosquito develop in containers around human habitations which can be numerous and labor intensive to find and treat. aerial applications of larvicide covering large areas in a short time can be an efficient and ... | 2017 | 28199323 |
| levels of insecticide resistance to deltamethrin, malathion, and temephos, and associated mechanisms in aedes aegypti mosquitoes from the guadeloupe and saint martin islands (french west indies). | in the guadeloupe and saint martin islands, aedes aegypti mosquitoes are the only recognized vectors of dengue, chikungunya, and zika viruses. for around 40 years, malathion was used as a mosquito adulticide and temephos as a larvicide. since the european union banned the use of these two insecticide molecules in the first decade of the 21st century, deltamethrin and bacillus thuringiensis var. israelensis are the remaining adulticide and larvicide, respectively, used in guadeloupe. in order to ... | 2017 | 28187780 |
| response of three cyprinid fish species to the scavenger deterrent factor produced by the mutualistic bacteria associated with entomopathogenic nematodes. | the symbiotic bacteria, photorhabdus and xenorhabdus associated with entomopathogenic nematodes (epns) in the genera heterorhabditis and steinernema, respectively, produce a compound(s) called the scavenging deterrent factor (sdf). sdf deters a number of terrestrial insect scavengers and predators and one bird species from feeding on host insects killed by the nematode-bacterium complex but has not been tested against aquatic vertebrates. moreover, the heterorhabditis-photorhabdus association is ... | 2017 | 27908637 |
| entomological investigations during early stages of a chikungunya outbreak in the united states virgin islands, 2014. | during the 2014 chikungunya (chik) outbreak in the caribbean, we performed entomological surveys on 3 united states virgin islands (usvi): st. croix, st. thomas, and st. john. we aimed to evaluate the potential for chikungunya virus (chikv) transmission in the usvi. the surveys took place between june 19, 2014, and june 29, 2014, during the dry season in usvi. a total of 1,929 adult mosquitoes belonging to 4 species- culex quinquefasciatus (68.4%), aedes aegypti (29.7%), ae. mediovittatus (1.3%) ... | 2017 | 28388320 |
| potential of aedes aegypti and aedes albopictus populations in the central african republic to transmit enzootic chikungunya virus strains. | major chikungunya outbreaks have affected several central african countries during the past decade. the chikungunya virus (chikv) was isolated from humans and sylvan mosquitoes in the central african republic (car) during the 1970 and 1980s but has not been found recently, despite the presence of aedes albopictus since 2010. the risk of a massive chikungunya epidemic is therefore potentially high, as the human populations are immunologically naïve and because of the presence of the mosquito vect ... | 2017 | 28347325 |
| computer-aided structure based drug design approaches for the discovery of new anti-chikv agents. | chikungunya is a viral infection caused by chikungunya virus (chikv), an arbovirus transmitted through mosquito (aedes aegypti and aedes albopictus) bite. the virus from sylvatic cycle in africa mutated to new vector adaptation and became one of the major emerging and re-emerging viral infections in the past decade, affecting more than 40 countries. efforts are being made by many researches to develop means to prevent and control the infection through vaccines and vector control strategy. on the ... | 2017 | 28294048 |
| chikungunya infection: a global public health menace. | chikungunya virus (chikv) has been involved in epidemics in african and asian subcontinents and, of late, has transcended to affect the americas. aedes aegypti and aedes albopictus are the major vectors for chikv infection, which results in dissemination of virus to various vital organs. entry of virus into these tissues causes infiltration of innate immune cells, monocytes, macrophages, neutrophils, natural killer cells, and adaptive immune cells. macrophages bearing the replicating virus, in t ... | 2017 | 28233156 |
| aedes-borne virus-mosquito interactions: mass spectrometry strategies and findings. | aedes-borne viruses are responsible for high-impact neglected tropical diseases and unpredictable outbreaks such as the ongoing zika epidemics. aedes mosquitoes spread different arboviruses such as dengue virus (denv), chikungunya virus (chikv), and zika virus, among others, and are responsible for the continuous emergence and reemergence of these pathogens. these viruses have complex transmission cycles that include two hosts, namely the aedes mosquito as a vector and susceptible vertebrate hos ... | 2017 | 28192064 |
| environmental and social change drive the explosive emergence of zika virus in the americas. | since zika virus (zikv) was detected in brazil in 2015, it has spread explosively across the americas and has been linked to increased incidence of microcephaly and guillain-barré syndrome (gbs). in one year, it has infected over 500,000 people (suspected and confirmed cases) in 40 countries and territories in the americas. along with recent epidemics of dengue (denv) and chikungunya virus (chikv), which are also transmitted by aedes aegypti and ae. albopictus mosquitoes, the emergence of zikv s ... | 2017 | 28182667 |
| severe chikungunya infection in northern mozambique: a case report. | although chikungunya virus has rapidly expanded to several countries in sub-saharan africa, little attention has been paid to its control and management. until recently, chikungunya has been regarded as a benign and self-limiting disease. in this report we describe the first case of severe chikungunya disease in an adult patient in pemba, mozambique. | 2017 | 28179029 |
| transcriptome analysis of aedes aegypti in response to mono-infections and co-infections of dengue virus-2 and chikungunya virus. | chikungunya virus (chikv) and dengue virus (denv) spread via the bite of infected aedes mosquitoes. both these viruses exist as co-infections in the host as well as the vector and are known to exploit their cellular machinery for their replication. while there are studies reporting the changes in aedes transcriptome when infected with denv and chikv individually, the effect both these viruses have on the mosquitoes when present as co-infections is not clearly understood. in the present study, we ... | 2017 | 28161634 |
| chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen. | re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public health concern. in the past 15 years, after decades of infrequent, sporadic outbreaks, the virus has caused major epidemic outbreaks in africa, asia, the indian ocean, and more recently the caribbean and the americas. chikungunya virus is mainly transmitted by aedes aegypti mosquitoes in tropical and subtropical regions, but the potential exists for further spread because of genetic adaptation of the virus t ... | 2017 | 28159534 |
| engineered aedes aegypti jak/stat pathway-mediated immunity to dengue virus. | we have developed genetically modified ae. aegypti mosquitoes that activate the conserved antiviral jak/stat pathway in the fat body tissue, by overexpressing either the receptor dome or the janus kinase hop by the blood feeding-induced vitellogenin (vg) promoter. transgene expression inhibits infection with several dengue virus (denv) serotypes in the midgut as well as systemically and in the salivary glands. the impact of the transgenes dome and hop on mosquito longevity was minimal, but it re ... | 2017 | 28081143 |
| identification and initial characterization of matrix metalloproteinases in the yellow fever mosquito, aedes aegypti. | aedes aegypti is a major vector for arboviruses such as dengue, chikungunya and zika viruses. during acquisition of a viremic bloodmeal, an arbovirus infects mosquito midgut cells before disseminating to secondary tissues, including the salivary glands. once virus is released into the salivary ducts it can be transmitted to another vertebrate host. the midgut is surrounded by a basal lamina (bl) in the extracellular matrix, consisting of a proteinaceous mesh composed of collagen iv and laminin. ... | 2017 | 28054419 |
| [chikungunya, an emerging viral disease. proposal of an algorithm for its clinical management]. | chikungunya fever (chik) is an emerging viral disease. it is caused by the chikungunya virus, an alphavirus from the togaviridae family. it is transmitted to humans by the bite of infected mosquitoes, mainly aedes aegypti and aedes albopictus. they are also involved in the transmission of dengue, malaria, etc. chik is now endemic in any region of africa and southeast-asia. cases of chik have been reported in america, the caribbean, and europe (france, italy and spain). there are reservoirs of th ... | 2017 | 25440971 |
| optimal control problems of mosquito-borne disease subject to changes in feeding behavior of aedes mosquitoes. | dengue viruses (denv) are transmitted to humans by the bite of aedes mosquitoes. it is known that dengue virus infection in aedes aegypti female mosquitoes makes a change in the feeding behavior of the infected mosquitoes. in this study, using the forces of infection, we incorporated the effect of changes in the feeding behavior of mosquitoes into the standard vector-borne sir-si model. it has been proved that both a single-strain model and a two-strain model exhibit forward bifurcations. moreov ... | 2017 | 28385591 |