Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [evaluation of the specificity of skin allergy tests in cattle with ibr-ipv]. | an allergic and serologic investigation was carried out by the skin allergic test (sat) and the virus neutralization test (vnt) to demonstrate the presence of infectious bovine rhinotracheitis -- infectious pustular vulvovaginitis (ibr-ipv) in cattle divided into three groups according to age, treated with the live attenuated vaccine mk25 against aujeszky's disease. it was found that this vaccine induced the production of specific antibodies against the virus of ibr-ipv, which could be demonstra ... | 1983 | 6306906 |
| [use of nonspecific agents and vaccination in bronchopneumonia prevention in cattle]. | a group of 463 calves, kept under one and the same conditions of tending and feeding, were followed up from the fifteenth day after birth up to one year of age, after treatment by subgroups with a hyperimmune antibovine rabbit serum, biomass of chlorella, a tissue preparation of swine embryos, and vaccines against mucosal diseases and infectious bovine rhinotracheitis. the experiment revealed that those of the calves that were treated with a combination of chlorella biomass and a hyperimmune ant ... | 1983 | 6306907 |
| [field trials of a number of ibr vaccines in dairy cattle]. | vaccination of ninety-six cows which showed titres of less than or equal to 1:2 on inoculation, using vaccines containing attenuated live ibr virus (tracherine, resbo. ibr pi3, respacine 3) elicited a moderate serological response. inoculation of these vaccines in 192 cows showing titres of greater than or equal to 1:3 on vaccination did not result in a significant increase in titre. inactivated ibr vaccines (iffavax and ibeair h) induced a satisfactory serological response in 140 cows, regardle ... | 1983 | 6308850 |
| [vaccination against ibr: a recommendation for dairy herds]. | in view of the results of previous serological studies on the presence of sn antibodies to ibr virus in a minimum of ten per cent of the herd, the following procedure is suggested: (1) vaccination of serologically negative herds in areas menaced by ibr virus. (2) vaccination of ibr-negative groups of animals in herds in which serologically ibr-positive animals are present. when sampling shows that ibr-negative animals are present in every age group, vaccination of the entire herd should be conte ... | 1983 | 6308851 |
| a mail survey of factors associated with morbidity and mortality in feedlot calves in southwestern ontario. | the design and results of a mail survey of a simple random sample of southwestern ontario feedlot owners are presented. the survey provided general data about management of feedlot calves and the association between a number of factors and disease and/or death rates. the number of calves purchased was related positively, in a linear manner, to mortality and morbidity rates. increased levels of morbidity and mortality were noted when the ration was changed to corn silage from dry-hay within the f ... | 1983 | 6309344 |
| the effect of dose, route and virulence of bovine herpesvirus 1 vaccine on experimental respiratory disease in cattle. | three experiments were conducted with calves in which, following intramuscular or intranasal vaccination with virulent or attenuated bovine herpesvirus 1, calves were protected against bovine herpesvirus 1 -- pasteurella haemolytica challenge. calves receiving low doses of vaccine had lower levels of antibody and greater evidence of virus replication upon challenge than those receiving higher doses. in contrast 11/13 unvaccinated controls had fibrino-purulent pneumonia following challenge. the i ... | 1983 | 6309347 |
| nonspecific suppressive effect of bovine herpesvirus type 1 on bovine leukocyte functions. | the effect of bovine herpesvirus type 1 on the specific and nonspecific immune response of calves was examined. animals with or without prior aerosol exposure to pasteurella haemolytica serotype a1 were aerosol challenged with 10(8) pfu of virus. blood and serum samples were taken before and after virus challenge for determining cell-mediated, humoral, and neutrophil responses. a significant depression of the blastogenic responses to phytohemagglutinin, p. haemolytica, and pasteurella multocida ... | 1983 | 6311742 |
| goat herpesviruses: biological and physicochemical properties. | two herpesvirus isolates from goats are known which cause afflictions of the digestive tract in kids and, in some cases, abortion. an antigenic relationship of these goat herpesviruses with infectious bovine rhinotracheitis/infectious pustular vulvo-vaginitis virus (bovid herpesvirus 1, bhv-1) was reported and because of the species-specific pathogenicity, the goat isolates were named caprine herpesvirus 1. in this report the two isolates are further characterized and compared with bhv-1. althou ... | 1983 | 6311953 |
| analysis of bovine herpes virus-type 1 isolates by restriction endonuclease fingerprinting. | in an effort to determine whether distinct types of bovine herpesvirus 1 are responsible for causing specific syndromes, the polypeptides and dna of 93 bhv 1 isolates from the province of alberta as well as vaccine strains and numerous other canadian, u.s. and european isolates were analyzed by page and restriction endonuclease fingerprinting, respectively. the polypeptide patterns showed only slight variations: only six isolates contained polypeptides that varied from the norm in their molecula ... | 1983 | 6312930 |
| efficacy of aerosol, intranasal and intramuscular vaccination against selected bovine viral diseases. | an experiment was designed to compare the efficacy of an im modified live vaccine, an in temperature-sensitive vaccine, an in modified live vaccine, and an aerosolized modified live vaccine (two concentrations) to stimulate specific serum antibody and protect calves from a known viral challenge. all vaccines except the im vaccine contained ibr virus and pi3 virus. the im vaccine and the in vaccines provided excellent protection to an ibr challenge, but both concentrations of aerosolized vaccine ... | 1983 | 6313292 |
| challenge exposure of cattle vaccinated with a chemically altered strain of pasteurella haemolytica. | calves vaccinated with a chemically altered strain of pasteurella haemolytica and their nonvaccinated controls were challenge exposed intranasally with the cooper strain of infectious bovine rhinotracheitis virus. five days later, the calves were challenge exposed intratracheally with the p haemolytica type a1. calves that had been vaccinated with large, medium, or small doses of the chemically altered vaccinal strain of p haemolytica had various degrees of resistance to the experimental challen ... | 1983 | 6314851 |
| characteristics of the polyriboinosinic acid:polyribocytidylic acid assay for noncytopathogenic bovine viral diarrhea virus. | the use of polyriboinosinic acid:polyribocytidylic acid (poly i:c) for noncytopathogenic bovine viral diarrhea virus (nc-bvdv) assay (pinba) was studied. several viruses were tested for their suitability as test challenge viruses. in addition to vesicular stomatitis virus, which previously was shown to be a suitable challenge virus, bovine enteroviruses also were found to be suitable, whereas infectious bovine rhinotracheitis virus and parainfluenza type 3 virus were only marginally suitable. bo ... | 1983 | 6314854 |
| a field trial, of preshipment vaccination, with intranasal infectious bovine rhinotracheitis-parainfluenza-3 vaccines. | a total of 849 calves, 278 controls, 335 vaccinated intranasally with ibr-pi3/ts and 236 vaccinated intranasally with ibr-pi3/ptc were studied in a field trial of preimmunization. all calves were vaccinated in saskatchewan at least three weeks prior to shipment to feedlots. four hundred and twenty six calves were not sold within eight weeks of vaccination; however, seven of these died within four weeks of vaccination. treatment rates varied from 1.0% to 5.2%. there was no significant effect of v ... | 1983 | 6315194 |
| prevention of experimental bovine pneumonic pasteurellosis with an extract of pasteurella haemolytica. | a total of 36 calves were used in three experiments to test the efficacy of a potassium thiocyanate extract of pasteurella haemolytica in protecting against experimental pneumonia. in each of experiments a and b, 12 calves were divided into three equal groups. the first group was vaccinated with an aerosol of a potassium thiocyanate extract twice, two weeks apart; the second group was vaccinated subcutaneously once only with the same extract. the third group of calves in both experiments remaine ... | 1983 | 6315195 |
| viral-bacterial pneumonia in calves: duration of the interaction between bovine herpesvirus 1 and pasteurella haemolytica. | sixteen six to eight month old beef calves were exposed individually to a five minute aerosol of bovine herpesvirus 1, isolate 108. aerosol exposure to pasteurella haemolytica (biotype a, serotype 1) was administered individually for five minutes at either four, ten, 20 or 30 days after the virus. fibrinous pneumonia and pleuritis occurred in all four groups but were most extensive and severe in those exposed to the virus and bacterium four days apart (the positive controls). fibrinous pneumonia ... | 1983 | 6315196 |
| the relationship of serology and nasal microbiology to pulmonary lesions in feedlot cattle. | a group of 62 beef calves, born and raised in an institutional herd, were transferred at nine months of age to a commercial feedlot where they remained until slaughter seven months later. clinical, immunological and microbiological monitoring was carried out during this period. no serious clinical illness occurred. one hundred percent seroconversion to bovine virus diarrhea virus took place after introduction of the calves into the feedlot as well as almost complete (59/62) seroconversion to bov ... | 1983 | 6315201 |
| prevalence of antibody to bovine herpesvirus 1 in wild ruminants captive in united states zoos. | serum samples (n = 1,146) representing 100 species of exotic ruminants now captive in united states zoos were assayed for neutralizing antibody to infectious bovine rhinotracheitis (ibr) virus (bovine herpesvirus 1). thirty-four animals (3%) of 11 species had antibody to ibr virus. because of the low prevalence of ibr antibody found, it was concluded that vaccination against ibr virus probably is not necessary for captive wild ruminants in united states zoos. | 1983 | 6315661 |
| epidemiology of bhv 1 virus infections in dairy herds. | the epidemiology of bovine herpesvirus 1 (bhv 1) infections was studied in 20 dairy herds. periodic serological surveillance of these herds during three consecutive years (1980-82) was combined with clinical studies. in 19 herds seropositive cows were found indicating previous exposure to bhv 1. one herd had its first experience with bhv 1 during the study. no indication of virus circulation for at least three years was found in eight herds. in five herds an interval of 2 years without an indica ... | 1983 | 6315812 |
| prevalence of bovine herpesvirus-1, parainfluenza-3, bovine rotavirus, bovine viral diarrhea, bovine adenovirus-7, bovine leukemia virus and bluetongue virus antibodies in cattle in mexico. | 1983 | 6316006 | |
| antibodies against viral pathogens in dairy cattle in colombia. | 1983 | 6316593 | |
| thymidine kinase (tk) induction after infection of tk-deficient rabbit cell mutants with bovine herpesvirus type 1 (bhv-1): isolation of tk- bhv-1 mutants. | cytosol thymidine kinase (tk) activity is enhanced at 6 hr after bovine embryo tracheal (ebtr) and rabbit skin fibroblast (rab-9) cells are infected with the los angeles and cooper strains of bovine herpesvirus type 1 (bhv-1). to learn whether this enhancement resulted from the induction of a virus-specific tk activity, biochemical and genetic studies were carried out. the biochemical experiments demonstrated that: (i) the bhv-1-induced tk activity had a relative disc page mobility (rm) characte ... | 1983 | 6316635 |
| suppressed lymphocyte blastogenic responses and enhanced in vitro growth of infectious bovine rhinotracheitis virus in stressed feeder calves. | hereford steers were stressed on a large-animal treadmill operating at speeds of 1.8 to 2.2 m/s. blood samples were collected from indwelling jugular catheters before, during, and after exercise. peripheral blood lymphocytes from stressed calves at 5 and 30 minutes after exercise had less (p less than 0.01) mitogen-induced blastogenic responses when compared to pre- or 60-minute postexercise values. serum from stressed calves incorporated into lymphocyte cultures from nonstressed steers resulted ... | 1983 | 6316823 |
| attempted reactivation of latent bovine herpesvirus 1 infection in calves by infection with ruminant pestiviruses. | three calves, latently infected with bovine herpesvirus 1 (bhv 1), were each inoculated intranasally with 9 strains of ruminant pestivirus (bvdv). all three calves developed a biphasic pyrexia and a lymphopenia followed by a neutrophilia. they did not shed bhv 1 in their nasal secretions in the 14 days following bvdv inoculation, and their bhv 1 antibody levels remained static, as did those of 2 control calves not given bvdv. all five calves were subsequently shown to be latently infected with b ... | 1983 | 6318422 |
| variation of virus replication in primary bovine kidney cell cultures derived from 68 three-day-old calves. | primary kidney cell cultures were prepared from 68 three-day-old calves. complete monolayers of these cultures were infected separately with viral diarrhea, infectious bovine rhinotracheitis, parainfluenza, and adenovirus 7 viruses. the yield of virus from all infected cultures was calculated by plaque titer assay after 2 to 4 days' incubation. the variation of virus yield was substantial between individual cultures. | 1983 | 6318615 |
| in vivo and in vitro effect of acyclovir on pseudorabies virus, infectious bovine rhinotracheitis virus and pigeon herpesvirus. | the effect of various concentrations of acyclovir on the mean plaque size of pseudorabies virus (shv), infectious bovine rhinotracheitis virus (ibr virus) and pigeon herpesvirus (phv) has been studied. acyclovir significantly reduced the mean plaque size of shv and phv, whereas ibr virus was less affected and did only show a reduction of the mean plaque size at the highest concentration of acyclovir used (1000 microm). in vivo effect of acyclovir was tested using pigeons and budgerigars experime ... | 1983 | 6318645 |
| serologic survey for selected microbial pathogens in alaskan wildlife. | antibodies to brucella spp. were detected in sera of seven of 67 (10%) caribou (rangifer tarandus), one of 39 (3%) moose (alces alces), and six of 122 (5%) grizzly bears (ursus arctos). antibodies to leptospira spp. were found in sera of one of 61 (2%) caribou, one of 37 (3%) moose, six of 122 (5%) grizzly bears, and one of 28 (4%) black bears (ursus americanus). antibodies to contagious ecthyma virus were detected in sera of seven of 17 (41%) dall sheep (ovis dalli) and five of 53 (10%) caribou ... | 1983 | 6139490 |
| [infectious bovine rhinotracheitis (vhb-1). ii. physico-chemical properties of strain l-114]. | the thermal stability, density gradient and morphological features of a recently isolated l-114 strain of infectious bovine rhinotracheitis virus were determined. morphology studies showed an enveloped virus with 200 nm of total diameter, a core diameter of 90 nm and an icosaedral-type structure; purified preparations contained both complete and empty viral particles. more than 90% of the infectivity was lost after 15 hours at 37 degrees c; at 56 degrees c, inactivation was much faster, with a 3 ... | 1982 | 6100998 |
| susceptibility of bovine macrophages to infectious bovine rhinotracheitis virus infection. | infectious bovine rhinotracheitis virus replicated in cultured bovine alveolar macrophages (am). however, yields of infectious virus were low, with maximum titers approximately 100 times that of the residual inoculum. immunofluorescence and electron microscopic studies indicated that the majority of macrophages produced viral antigen, but after infection at a multiplicity of 0.1, only 4.1% of am produced infectious centers. virus-infected am culture supernatants possessed interfering activity, p ... | 1982 | 6175574 |
| duration of protection of calves against rhinovirus challenge exposure by infectious bovine rhinotracheitis virus-induced interferon in nasal secretions. | six calves inoculated intranasally with a vaccinal strain of infectious bovine rhinotracheitis (ibr) virus and 6 control calves were given a placebo. all calves were subsequently challenge exposed (by aerosol) with rhinovirus--3 of the calves from each group at 2 days after they were inoculated with ibr virus or with placebo and the remaining calves at 6 days. nasal excretion of viruses, interferon (ifn) concentrations in nasal secretions (ns), and neutralizing antibody in sera and ns were deter ... | 1982 | 6178325 |
| bovine herpesvirus-1 vaccination against experimental bovine herpesvirus-1 and pasteurella haemolytica respiratory tract infection: onset of protection. | the onset of protection offered by intranasal vaccination with attenuated bovine herpesvirus-1 (bhv-1) was studied in 18 calves given a virulent bhv-1 aerosol challenge inoculum and an aerosol challenge exposure to pasteurella haemolytica. calves challenge exposed with virus 3, 7, 11, 15, or 19 days after vaccination and challenge exposed 4 days later with pasteurella haemolytica did not develop viral-bacterial pneumonia, whereas 2 of 3 control calves died of fibrinous bronchopneumonia 40 and 60 ... | 1982 | 6183996 |
| [interferon induction in calves after experimental infection with bovine herpesvirus 1]. | a total of 9 calves were used to test the interferon-inducing activity of strain vulchedrum of the bovid herpes virus 1. the virus of stomatitis vesiculosa adapted to cell cultures of calf kidney was used as an indicator of interferon. the antiviral action of interferon was demonstrated in the serum and the nose discharge of calves. the dynamics of interferon production in calves varied, depending on the venous, muscular, and tracheal route of application of the virus. highest interferon titer i ... | 1982 | 6188269 |
| persistent infection with bovine herpesvirus type 1: rabbit model. | persistent infection with bovine herpesvirus type 1 (bhv-1) was established in all rabbits after conjunctival inoculation of virus. spontaneous reactivations of bhv-1 with and without the appearance of recurrent ocular lesions were observed in persistently infected rabbits. bhv-1 was reactivated predictably and shed from all persistently infected rabbits after the administration of dexamethasone. during all reactivations, bhv-1 isolation was restricted to the inoculated eye. | 1982 | 6274801 |
| rapid detection of antibodies to infectious bovine rhinotracheitis by 'macro' and 'micro' elisa. | two kinds of enzyme-linked immunosorbent assay were evaluated in their ability to detect specific antibodies against bovine rhinotracheitis virus (ibr-ipv). the tests were called macroelisa and microelisa, according to the kind of the solid support used for antigen insolubilization, polystyrene beads and microtitration plates respectively. partially purified virus was used to coat both beads and plates; a single dilution of examples was tested and protein a linked to peroxidase was employed as e ... | 1982 | 6299826 |
| infectious bovine rhinotracheitis: study on the experimentally induced disease and its prevention using an inactivated, adjuvanted vaccine. | experimentally induced ibr was studied in calves. intranasal challenge enabled reproducible results to be obtained, both from qualitative (clinical aspect) and quantitative points of view (virus excretion, temperature); local and general immunity were also evaluated. this challenge method is useful when studying ibr vaccines. the disease was also experimentally induced by putting healthy animals into contact with diffusor calves. a single injection of inactivated vaccine in oily adjuvant already ... | 1982 | 6299856 |
| isolation of infectious bovine rhinotracheitis virus from the soft-shelled tick, ornithodoros coriaceus. | infectious bovine rhinotracheitis virus was isolated from the soft-shelled tick (ornithodoros coriaceus). serological identification of the isolated viruses was confirmed by restriction endonuclease digestion of purified virus dna. these isolations indicate that the soft-shelled tick may be a vector for infectious bovine rhinotracheitis virus. this may be the first reported isolation of mammalian herpesvirus from an arthropod vector. | 1982 | 6278596 |
| effect of infectious bovine rhinotracheitis virus infection on bovine alveolar macrophage function. | bovine alveolar macrophages isolated in culture were assessed for immunological activity in assays for fc and complement receptors, for phagocytosis, and for effector cell function in antibody-dependent cell cytotoxicity. in the case of uninfected alveolar macrophages, fc receptors were detected on approximately 94% of macrophages and complement receptors were detected on 39%. phagocytosis of immunoglobulin g-coated sheep erythrocytes occurred in 58% of macrophages, and phagocytosis of opsonized ... | 1982 | 6279511 |
| bovid herpesvirus 2 latency: failure to recover virus from central sensory nerve ganglia. | latent bovid herpesvirus 2 was sought in sensory ganglia, epithelium and lymph nodes from cattle having antibodies against bovid herpes virus 2. tissues from eight animals were maintained in vitro as explants for 49-72 days during which all expended media was tested for virus. three animals were pretreated with corticosteroids prior to slaughter. infectious bovine rhinotracheitis virus was recovered from one animal, but bovid herpesvirus 2 was not detected. | 1982 | 6280823 |
| [possibilities and limits of md/vd and ibr vaccination in a cattle fattening stable. observations of a case in practice (author's transl)]. | 1982 | 6280958 | |
| dna of bovine herpesvirus type 1 in the trigeminal ganglia of latently infected calves. | twelve calves infected with bovine herpesvirus type 1 (bhv-1) were killed when in a latent state of infection. latency was verified 30 days after virus inoculation of the calves by seroconversion, absence of virus shedding, and in 2 calves, by recrudescence of the infection after they were treated with dexamethasone. by in situ hybridization techniques and autoradiography, dna of bhv-1 was detected in 13 of 23 trigeminal ganglia of latently infected calves. viral dna was restricted to the nucleu ... | 1982 | 6283952 |
| vaccination of cattle against pseudorabies (aujeszky's disease) with homologous virus (herpes suis) and heterologous virus (herpes bovis 1). | study was made to determine whether vaccination of cattle against pseudorabies (pr; aujeszky's disease) affords protection upon subsequent intranasal challenge exposure with virulent virus. vaccinations were performed with a commercially available oil-adjuvant pr virus vaccine, in some cases supplemented with a1(oh)3 (given subcutaneously), with the attenuated nia4 strain of pr virus (given intranasally), and with a commercially available temperature-sensitive mutant of bovine herpesvirus-1 (inf ... | 1982 | 6283963 |
| natural cell-mediated cytotoxicity of bovine mononuclear cells against virus-infected cells. | the ability of mononuclear cells (mc) from peripheral blood of normal cattle to lyse a variety of cells was tested in a 51cr-release microcytotoxicity assay. several types of bovine cells infected with parainfluenza 3 virus (pi3v) were susceptible to natural cytotoxicity. bovine cells infected with infectious bovine rhinotracheitis virus or noncytopathogenic bovine viral diarrhea virus, uninfected bovine cells, and human cell lines molt-3, hsb-2, k562, and u-937 were not susceptible. the period ... | 1982 | 6284642 |
| virologic study of the reproductive tract in dairy cows. | from aug 1, 1979 to aug 15, 1980, a total of 624 samples were collected from the vaginas, cervices, and uteri of 208 dairy cows 30 to 37 days after parturition. an additional 90 samples were collected from the reproductive tracts from 30 of the 208 cows. the 30 cows had aborted or were repeat breeders. samples from cows that had aborted were collected within a week after clinical abortion or immediately after rectal palpation revealed subclinical abortion. all samples were tested for the presenc ... | 1982 | 6285771 |
| effect of levamisole in immune responses to bovine herpesvirus-1. | the effect of levamisole on bovine immune responses to infectious bovine rhinotracheitis virus was assessed under laboratory and commercial feedlot situations. in all instances, levamisole appeared to have a beneficial effect on antibody responses of the cattle after vaccination. in the smaller scale pilot trials, levamisole appeared to be more efficacious when given 7 days after vaccination, presumably when a large amount of viral antigens was present as a result of viral replication. in the la ... | 1982 | 6285779 |
| association between route of inoculation with infectious bovine rhinotracheitis virus and site of recrudescence after dexamethasone treatment. | four calves latently infected with infectious bovine rhinotracheitis virus (ibrv) were used to compare the ease of isolation of virus from neuronal ganglia and from mucosal surfaces. two calves were slaughtered, and neuronal ganglia (cranial cervical, trigeminal, and 3rd and 4th sacral) were cocultivated on bovine fetal kidney cells. virus was not isolated. two calves given dexamethasone for 4 days were slaughtered on the 5th day. virus was not isolated from cocultivated or macerated neuronal ga ... | 1982 | 6285780 |
| prevalence of bovine herpesvirus-1, bovine oral diarrhea, parainfluenza-3, bovine adenoviruses-3 and -7, and goat respiratory syncytial viral antibodies in goats. | sera from healthy goats were collected during october 1979 through october 1980. these sera were tested for bovine herpesvirus-1 (bhv-1), bovine viral diarrhea virus (bvdv), parainfluenza-3 (pi-3) virus, bovine adenoviruses (bav) -3 and -7, and goat respiratory syncytial virus (grsv) antibodies by microtitration virus-neutralization test. the number of herds with seropositive goats for each virus were: 5/38 (13.2%) for bhv-1; 9/38 (23.7%) for bvdv; 8/38 (21.1%) for pi-3 virus; 1/38 (2.6%) for ba ... | 1982 | 6285781 |
| safety and efficacy of live and inactivated infectious bovine rhinotracheitis vaccines. | two commercial live virus infectious bovine rhinotracheitis (ibr) vaccines for intranasal administration and an inactivated polyvalent calf pneumonia vaccine were compared for safety and efficacy in calves against experimental ibr infections. all three products were clinically safe for use in young calves; a mild, transient, febrile response was induced by one of the live vaccines. vaccinal virus was recovered for up to 16 days after vaccination from nasal secretions of all calves given live vac ... | 1982 | 6289508 |
| a review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle. | unanswered questions on the etiology and prevention of shipping fever pneumonia have allowed this disease to remain one of the most costly to the north american cattle industry. research in this area has indirected that while pasteurella haemolytica and, to a lesser extent, p. multocida are involved in most cases, they seem to require additional factors to help initiate the disease process. bovine herpes virus 1 has been shown experimentally to be one such factor. this review examines in some de ... | 1982 | 6290011 |
| immune responses of dairy cattle to parainfluenza-3 virus in intranasal infectious bovine rhinotracheitis-parainfluenza-3 virus vaccines. | two hundred and fifty dairy heifers were vaccinated at three to six months of age with an intranasal infectious bovine rhinotracheitis-parainfluenza-3 vaccine. eighteen additional heifers were tested prior to vaccination and again three to four weeks after vaccination. neither cell-mediated nor humoral immunity was significantly raised to parainfluenza-3 virus in either group of cattle. | 1982 | 6290012 |
| aerosol vaccination of calves with pasteurella haemolytica against experimental respiratory disease. | three experiments were conducted on calves in which the efficacy of vaccination with live pasteurella haemolytica in aerosol was tested by challenge with sequential aerosol exposure to bovine herpesvirus 1 and p. haemolytica. neither single nor multiple aerosol vaccinations protected against the experimental disease. macroscopically recognizable rhinitis, tonsillitis, tracheitis and pneumonia occurred in both controls and vaccinates. in one experiment as many as three aerosol vaccinations with l ... | 1982 | 6290014 |
| effect of infectious bovine rhinotracheitis virus immunization on viral shedding in challenge-exposed calves treated with dexamethasone. | calves not vaccinated with infectious bovine rhinotracheitis virus (ibrv) became latently infected when challenge exposed and treated with dexamethasone (dm). calves that shed ibrv after dm treatment were considered to be latently infected. vaccination with a temperature-sensitive intranasal vaccine or with formalinized ibrv in freund's complete adjuvant (ibrv-fca) protected some, but not all, calves against latent infection--indicating a role for the immune response in preventing latent infecti ... | 1982 | 6293350 |
| respiratory tract immune response to microbial pathogens. | effective resistance to respiratory tract infection depends principally on specific immunity on mucosal surfaces of the upper or lower respiratory tract. respiratory tract immune response comprises antibody and cell-mediated systems and may be induced most readily by surface presentation of replicating agents but can result from parenteral or local presentation of highly immunogenic antigens. upper and lower respiratory tract systems differ in immunologic competence, with the lungs having a grea ... | 1982 | 6294027 |
| theory and practice of immunoprophylaxis in cattle. | 1982 | 6294031 | |
| importance of competitive binding in the detection of antigen specific bovine isotypes and subisotypes by the micro elisa. | an enzyme-linked immunosorbent assay was developed to detect and quantify the specific bovine immunoglobulin class response to trypanosoma theileri, dictyocaulus viviparus and infectious bovine rhinotracheitis virus. comparative measurement of the specific immunoglobulin classes in whole serum was achieved using monospecific rabbit antibovine igg1, igg2 and igm, followed by a goat anti-rabbit ig-enzyme conjugate (antiglobulin elisa). the results obtained in the antiglobulin elisa compared favour ... | 1982 | 6296953 |
| bovid herpesvirus 1 infection of cattle: pathogenesis, latency, consequences of latency. | 1982 | 6303191 | |
| non-specific antiviral activity of bovine leukocytes against infectious bovine rhinotracheitis virus in vitro. | leukocytes collected from bovine blood inhibit the multiplication of virus in ibr infected mdbk cells. this inhibition is non-specific and can be observed in the absence of serum. number of infected cells, number of leukocytes per infected cell and time of placing of leukocytes onto infected cells are some of the important factors in this protection. we observed variations between animals, but for each animal the activity of leukocytes was constant for several months. contact between leukocytes ... | 1982 | 6303192 |
| preliminary survey for antibodies against five bovine viruses in cattle in korea. | 1982 | 6302359 | |
| [timing of sensitization and appearance of skin allergic reaction in infectious bovine rhinotracheitis--infectious pustular vulvovaginitis]. | allergic and serologic investigations were carried out on infectious bovine rhinotracheitis--infectious pustular vulvovaginitis with cattle artificially and spontaneously affected with the causative agent of the disease as well as with cattle that were treated with a live attenuated vaccine. it was found that in the case of experimental infection the allergization of the body and the positive skin allergic reaction set in as early as the 7th day of the disease while in the case of vaccination th ... | 1982 | 6304991 |
| pathological changes in young and adult cattle after intranasal inoculation with infectious bovine rhinotracheitis virus. | 1982 | 7068953 | |
| distribution of pasteurella haemolytica and pasteurella multocida in the bovine lung following vaccination and challenge exposure as an indicator of lung resistance. | experimental calves were vaccinated with virulent strains of pasteurella haemolytica or pasteurella multocida or with phosphate-buffered saline solution either by an aerosol method or by subcutaneous injection. calves were subsequently challenge exposed by intrapulmonic inoculation of the homologous virulent pasteurella species. sections obtained from the resulting pulmonic lesion were stained, using a fluorescent antibody technique, to determine relative number, location, and integrity of the c ... | 1982 | 7073058 |
| effect of infectious bovine rhinotracheitis virus infection of calves on cell populations recovered by lung lavage. | calves were challenge exposed with infectious bovine rhinotracheitis (ibr) virus, and experiments were carried out to determine the presence of virus in the lungs, virus or viral antigen in alveolar macrophages, and alterations in immune functions of alveolar macrophages. in experiment 1, calves were challenge exposed intranasally with ibr virus. although clinical signs of ibr occurred in all challenge-exposed calves, there was minimal evidence of virus or viral antigen in cells lavaged from the ... | 1982 | 7103198 |
| effect of lymphocytes and broncho-alveolar washing cells on the replication of bovine herpesvirus type 1 in tracheal organ cultures. | the daily addition of lymphocytes collected from a calf between 7 and 11 days after experimental infection with bovine herpesvirus type 1 (bhv-1) to bovine fetal tracheal organ cultures after infection with bhv-1 did not inhibit virus replication. the daily addition of normal lymphocytes, together with a low concentration of serum antibody against bhv-1, had a slight viral inhibitory effect which was believed to be due to antibody-dependent cell-mediated cytotoxicity. the addition of broncho-alv ... | 1982 | 7112897 |
| herpesvirus-induced "early" glycoprotein: characterization and possible role in immune cytolysis. | glycoprotein gvp-11 (molecular weight, 71,500), induced by bovine herpesvirus type 1, was detected on the external surface of infected cells. it could be categorized as an "early" or "beta" class protein since it was synthesized early in the infectious process and its expression was not dependent upon prior viral dna replication in the infected cells. monoclonal antibodies directed against gvp-11 immunoprecipitated that glycoprotein and some low-molecular-weight polypeptides from infected cells ... | 1982 | 7143563 |
| a method to test large numbers of bovine semen samples for viral contamination and results of a study using this method. | a procedure to test large numbers of semen samples for viral contamination is described. the procedure has the advantages of being simple to perform, sensitive and a relatively inexpensive method to test pooled semen samples, but it has the disadvantage of requiring serologically negative calves and sheep, isolation facilities to prevent environmental contamination during the testing procedure and relatively long times to obtain results. using this in vivo procedure called the "cornell semen tes ... | 1982 | 16725672 |
| embryo transfer as a means of controlling the transmission of viral infections. ii. the in vitro exposure of preimplantation bovine embryos to infectious bovine rhinotracheitis virus. | bovine embryos, at the 16-cell to the blastocyst stage of development, were exposed to infectious bovine rhinotracheitis virus (ibrv) for either one or 24 hours. these embryos were then washed and incubated for 24 or 48 hours before being assayed for ibrv. under these conditions, infectious virus at the level of 0-10(2.2) tcid(50)/ml was isolated from 57-64% of the embryos exposed to ibrv. trypsin and ibrv-antiserum were found to be capable of removing and/or inactivating the ibrv from exposed e ... | 1982 | 16725735 |
| an outbreak of vulvovaginitis in goats caused by a caprine herpesvirus. | a caprine herpesvirus related to infectious bovine rhinotracheitis virus but immunologically distinct from that virus was isolated from an outbreak of vulvovaginitis in a herd of saanen goats. the morbidity rate was 52.5%, with 21 of 40 does showing clinical signs. the lesions healed rapidly with only two goats showing lesions two weeks after the disease was first detected. no effect on subsequent reproductive performance was observed. the mode of transmission of the virus was believed to be ven ... | 1982 | 16030825 |
| recrudescence of infectious bovine rhinotracheitis virus and associated neural changes in calves treated with dexamethasone. | reactivation of infection bovine rhinotracheitis (ibr) virus in calves administered dexamethasone (dm) was studied in 2 experiments. at 2, 3, 5, 15, or 30 months after inoculation of the los angeles strain of ibr virus, iv injections of dm were given for 5 consecutive days to induce a recurrent infection (experiment 1). three months after the 1st treatment, a 2nd recurrent infection was induced, using dm with the same doses as used in experiment 1. the virus was excreted from nasal secretions fr ... | 1981 | 6267968 |
| serologic survey for selected microbial agents in mammals from alberta, 1976. | blood samples were taken from humans and several species of free-ranging wild mammals from five different geographic areas of alberta, canada. sera were tested for antibody to eastern equine encephalitis (eee) virus, western equine encephalitis (wee) virus, st. louis encephalitis (sle) virus, powassan (pow) virus, the snowshoe hare (ssh) strain of the california group (cal) of viruses, northway (nor) virus, klamath (kla) virus, infectious bovine rhinotracheitis (ibr) virus, and two bacteria, bru ... | 1981 | 6273600 |
| risk factors related to the prevalence of infectious bovine keratoconjunctivitis. | a cross-sectional epizootiologic study was conducted by mailed questionnaire to determine how the prevalence of infectious bovine keratoconjunctivitis (ibk) related to selected predisposing causes. the prevalence of ibk in missouri during the summer of 1978 was 4.97 cases/100 cattle, with 45% of respondents reporting cases of ibk. a higher prevalence of ibk was associated with calves and yearlings, hereford and hereford-cross cattle, backgrounding cattle operations, and herds with a history of i ... | 1981 | 6281222 |
| [virus neutralization microreaction to determine antibodies against the infectious bovine rhinotracheitis virus]. | comparative studies were carried out with a total of 170 serum samples from cattle with the use of the virus-neutralization test and the virus-neutralization microreaction to demonstrate the presence of antibodies against the ibr virus. it was found that the two reactions were equally effective in terms of specificity. the coincidence of the results obtained with regard to the positive and negative tests was 97 per cent with variant alfa and 98 per cent with variant beta. comparatively higher se ... | 1981 | 6283727 |
| levamisole and bovine immunity: in vitro and in vivo effects on immune responses to herpesvirus immunization. | levamisole was shown to enhance in vitro blastogenic responses of bovine lymphocytes to nonspecific mitogens (phytohemagglutinin and pokeweed mitogen) as well as to infectious bovine rhinotracheitis virus and purified protein derivative. greatest enhancement was observed at suboptimal concentrations of viral antigen. in addition to enhancing lymphocyte reactivity levamisole also affected macrophage activity as determined by increased fc receptor activity and [3h]glucosamine incorporation. levami ... | 1981 | 6174193 |
| detection of bacteremia in cattle inoculated with bovine viral diarrhea virus. | bovine viral diarrhea virus infection of cattle interfered with normal blood clearance mechanisms, as evidenced by the detection of an endogenous bacteremia in up to 85% of infected calves during the first 5 days after infection. the occurrence of detectable bacteremia correlated with the period of leukopenia and depression of lymphocyte responses to mitogens. noninoculated control animals, reinoculated immune calves, or calves inoculated with infectious bovine rhinotracheitis virus yielded cons ... | 1981 | 7258771 |
| failure of a subunit bovine herpesvirus 1 vaccine to protect against experimental respiratory disease in calves. | in two experiments in which 31 calves were used, a bovine herpesvirus 1 subunit vaccine previously shown to elicit a strong immunological response in adult cattle failed to do so in younger animals and failed to protect against pneumonia caused by sequential exposure to virulent bovine herpesvirus 1 and pasteurella haemolytica aerosols. one of the experimental groups had been previously inoculated with a live commercial vaccine but even this failed to elicit a strong immunological response. thes ... | 1981 | 7272846 |
| proteins specified by bovine herpesvirus 1 (infectious bovine rhinotracheitis virus). | an electrophoretic analysis of radioactively labeled, purified, "empty" and dna-containing infectious bovine rhinotracheitis virions revealed the presence of 25 to 33 structural (virion) polypeptides. a total of 11 of these polypeptides could be labeled with [3h]glucosamine and were identified as glycoproteins. in addition to the 25 structural polypeptides, infectious bovine rhinotracheitis virus infected cells also contained at least 15 nonstructural (nonvirion) polypeptides that were not prese ... | 1981 | 6275094 |
| further studies of naturally occurring latent bovine herpesvirus infection. | attempts were made to enhance the isolation rate of latent bovine herpesviruses from trigeminal ganglia by using a fibroblastic fetal bovine kidney cell line, in addition to madin-darby bovine kidney cells, and by superinfecting with a temperature-sensitive helper strain of bovine herpesvirus-1 (bhv-1). four isolates of latent bhv-1 were obtained from 44 pairs of trigeminal ganglia--thus reflecting no increase in isolation rate over that previously observed. two isolates of a latent bovine herpe ... | 1981 | 6275750 |
| [multiplication of the ibr, pi-3 and bvd-md viruses in cell and organ cultures of bovine fetuses after experimental intrauterine infections]. | the intrauterine infection of four- to nine-month-old bovine foetuses with the pi-3, bvd-md viruses, performed 7 to 72 days prior to their delivery, did not exert any significant influence upon the susceptibility of primary cell cultures from foetal organs and tissues to further viral infection in vitro. the bvd-md and ibr viruses multiplied in the primary cell cultures from the organs of a foetus infected with the pi-3 virus seven days before delivery even in the presence of endogenous pi-3 vir ... | 1981 | 6277081 |
| the prevalence of serum neutralizing antibodies to infectious bovine rhinotracheitis virus in scotland. | the prevalence of serum neutralizing antibodies to infectious bovine rhinotracheitis virus in 1152 serum samples from adult cattle in 114 dairy and beef herds in different regions of scotland was 12%. in the grampian region, the number of seropositive cattle in the self-contained herds was significantly less (p less than 0.01) than in the "other" herds. holstein cattle had been introduced into five of these "other" herds, and significantly more (p less than 0.01) of the samples from these five h ... | 1981 | 6257782 |
| induction of persistent infection in mice and oncogenic transformation of mouse macrophages with infectious bovine rhinotracheitis virus. | infectious bovine rhinotracheitis virus (ibrv) established long-term persistent infection in intracerebrally inoculated athymic nude mice. after intraperitoneal injection into outbred mice, virus was isolated for only 3 days from spleens and livers. in vitro inoculation of outbred mouse spleen fragments with ibrv resulted in persistent infection and subsequent transformation of spleen macrophages. the ibrv-specific membrane and intracellular antigens were detected by indirect immunofluorescence ... | 1981 | 6266290 |
| bovine herpesvirus type 1 in the sperm of a bull from a herd with fertility problems. | a herd of 125 holstein cows manifested fertility problems for two years. the number of services per pregnancy was 2.97, conception rate was 33% after the first service, and the average number of open days was 127. abortions occurred in four cows over the last 12 months. the herd was not vaccinated against any disease. natural service by a bull and artificial insemination were used for breeding the cows. bovine herpesvirus type 1 was demonstrated in sperm heads from the bull by direct and indirec ... | 1980 | 6266630 |
| [antigen isolation and the applicability of a microvariant of the complement fixation reaction in infectious bovine rhinotracheitis]. | comparative investigations were carried out on 3 ibr cellular cultural antigens with regard to the cf-micromethod, produced by different methods. the best qualities with regard to sensitivity and specificity were reached by the antigen concentrated by ultracentrifuging. high coincidence rate was observed in discovering ibr antibodies in the blood serums of cows through the cf and vnr tests--96% of the positive and negative results although the cf reaction showed lower sensitivity. a conclusion w ... | 1980 | 6261439 |
| [protective action of inactivated adjuvant ibr vaccine against experimental infection in cattle]. | 1980 | 6243812 | |
| a seroepidemiologic survey of three pronghorn (antilocapra americana) populations in southeastern idaho, 1975-1977. | sera from 104 adult and 42 fawn pronghorn antelope (antilocapra americana) from southeastern idaho were tested against selected livestock pathogens. the numbers positive/numbers tested (% positive) were as follows: bovine virus diarrhea - adults 2/102 (2), fawns 0/41 (0);; infectious bovine rhinotracheitis - adults 27/101 (27), fawns 9/42 (22); parainfluenza 3 - adults 79/104 (76), fawns 22/42 (52); bovine adenovirus 7 - adults 42/103 (41), fawns 20/48 (48); bovine adenovirus 3 - adults 11/32 (3 ... | 1980 | 6246285 |
| evaluation of the rabbit as a laboratory model for infectious bovine rhinotracheitis virus infection. | experimental infection of rabbits with infectious bovine rhinotracheitis virus (ibrv) produced diverse manifestations of disease which included abortion, conjunctivitis, dermatitis, vulvovaginitis, systemic infection, neonatal death and respiratory tract infection. each disease syndrome was studied using virus isolation, fluorescent antibody examination and histologic examination. conjunctivitis, dermatitis and vulvovaginitis lesions were characterized by edema, infiltration of mucosa and submuc ... | 1980 | 6247121 |
| rapid onset of immunity in cattle after intramuscular injection of a modified-live-virus ibr vaccine. | 1980 | 6254226 | |
| neutrophils in antiviral immunity: inhibition of virus replication by a mediator produced by bovine neutrophils. | neutrophils collected from bovine mammary glands were placed in culture with virus-infected cell preparations that had been inactivated by ultraviolet light. upon culture with infectious bovine rhinotracheitis (ibr) virus-infected georgia bovine kidney cells, a material was released from the neutrophils that, like interferon, inhibited the replication of vesicular stomatitis virus and ibr virus. cell-free ibr virus was a less effective inducer of the inhibitor produced by neutrophils. other herp ... | 1980 | 6154112 |
| isolation of bovine herpesvirus-1 from trigeminal ganglia of clinically normal cattle. | trigeminal ganglia collected from 56 adult dairy cattle at slaughter were maintained in explant culture. bovine herpesvirus-1 was isolated from six ganglia after periods of 7 to 24 days' maintenance in vitro. antibody against bovine herpesvirus-1, indicating exposure to that virus, was found in 45.4% of the sample population from which ganglia were collected. | 1980 | 7447114 |
| the pathological features of severe cases of infectious bovine rhinotracheitis. | in recent outbreaks of infectious bovine rhinotracheitis (ibr) in britain a proportion of the animals affected developed a severe clinical disease characterised, at necropsy, by widespread damage to the respiratory tract. they had necrotising rhinitis, pharyngitis, laryngotracheobronchitis with extensive pseudomembrane formation and severe pneumonia with or without interstitial emphysema. renal infarction was seen in approximatley half of the cases. the central nervous system was not affected in ... | 1980 | 7456296 |
| scanning electron microscopy of the tracheal epithelium of calves inoculated with bovine herpesvirus 1. | tracheal epithelium was examined by light, scanning electron and transmission electron microscopy at four, five and seven days after calves were infected intranasally with bovine herpesvirus. similar areas were examined from uninoculated calves. tracheal epithelial lesions were found in all inoculated calves and their degree of severity did not vary with the interval between inoculation and examination. extensive loss of cilia leaving areas of tracheal epithelium covered by microvilli was the ma ... | 1980 | 7255893 |
| immunologic effects of experimental iodine toxicosis in young cattle. | a study was designed to evaluate effects of 4 dosage levels (0, 50, 250, or 1,250 mg) of daily iodine supplementation on cell-mediated and humoral immune mechanisms in 40 calves, 10 per group, for a 6-month period. immune and inflammatory responses were measured by titers to brucella, leptospira, and infectious bovine rhinotracheitis virus vaccinations, by stimulation of lymphocyte mitoses with poke-weed, phytohemagglutinin (pha), and conconavalin a mitogens, by intradermal pha responses, by in ... | 1980 | 6996540 |
| [immunization effectiveness of the inactivated vaccine against infectious bovine rhinotracheitis (ibr) with an oily adjuvant]. | the adjuvant vaccine against infectious bovine rhinotracheitis (ibr) was tested as to its innocuousness and immunogenicity. the immunity response induced by a single or double application of different vaccine doses was evaluated according to the content of neutralization antibodies (np) in the blood serum. a direct dependence was revealed between the size of the inoculum and np content in the blood serum, with np titres of 1 : 9.3; 1 : 26.6, 1 : 80 and 1 : 149 after doubled application of 1, 2, ... | 1979 | 223270 |
| immune response of cattle to antigens obtained from bovine herpesvirus 1-infected tissue culture. | the ability of two antigens, termed ev and cm, derived from bovine herpesvirus 1 infected cultures to produce serum-virus neutralizing antibodies has been studied in cattle. both ev and cm when inoculated with adjuvant induced significant increases in serum-virus neutralizing antibody titers. control groups inoculated in a similar manner failed to induce significant increases in serum-virus neutralizing antibody. some of the animals were vaccinated, then were bred, challenged with a virulent str ... | 1979 | 226245 |
| [isolation of infectious bovine rhinotracheitis virus from the tarsal joint of a bull (author's transl)]. | isolation of infectious bovine rhinotracheitis virus from the tarsal joint of a bullinfectious bovine rhinotracheitis virus was isolated from the right tarsal joint of a bull who was showing signs of a systemic viral infection. the clinical signs manifested by 16 bulls of this herd are described, the laboratory methods used are listed and the results are analysed and discussed. | 1979 | 227556 |
| properties of human epithelioid cells established in vitro by a herpesvirus [ibrv(hmc)] isolated from cytomegalovirus-transformed human cells. | infectious bovine rhinotracheitis virus [ibrv(hmc)], a double-enveloped herpesvirus, was isolated from human embryo lung fibroblasts transformed by cytomegalovirus (cmv). this agent was identified as an ibrv strain that was antigenically related to human cmv. inoculation of a primary human kidney cancer cell culture with ibrv(hmc) resulted in persistent infection and subsequent establishment of a cell line [ibrv(hmc)hkc-1]. virus-related nuclear, cytoplasmic, and cell membrane antigens were dete ... | 1979 | 229291 |
| experimental infection of eastern cottontail rabbits sylvilagus floridanus) with infectious bovine rhinotracheitis virus. | experimental infection of eastern cottontail rabbits (sylvilagus floridanus) with infectious bovine rhinotracheitis virus caused acute keratoconjunctivitis and a fatal systemic infection. the clinical syndrome was characterized initially by blepharospasm and ocular discharge. the rabbits were markedly depressed on post-exposure day (ped) 5 and were dead or moribund on ped 6. the virus was readily recovered from liver and adrenal gland tissue on ped 6 and from conjunctival swabs on ped 1 to 6. hi ... | 1979 | 230773 |
| [production and study of the immunogenic properties of a bivalent inactivated vaccine against mucosal disease (bovine viral diarrhea and infectious rhinotracheitis)]. | bivalent inactivated vaccine against mucous disease (md) and infectious rhinotracheitis (ir) in cattle was produced from cell cultural md and ir virus suspensions. the vaccine was concentrated on aluminium hydroxide, inactivated by ethanol and is without residual virus. saponine in final 1:1500 dilution is added as supplementary adjuvant. immunogeneity of the vaccine was tested on 10-month-old calves, which had shown full resistance against experimental infection with virulent strains of both vi ... | 1979 | 232586 |
| neural changes in recurrent genital infection of infectious bovine rhinotracheitis virus in calves treated with dexamethasone. | recurrent genital infection with infectious bovine rhinotracheitis (ibr) virus was induced in calves by dexamethasone (dm) treatment 3 months after primary infection. the virus was first recovered from vaginal secretions on the 3rd day after the initiation of dm treatment; however, the virus was not recovered at all from nasal secretions or from the cerebrospinal fluid of the dm-treated calves. the significant neural changes in all recurrent infected calves were nonsuppurative poliomyelitis in t ... | 1979 | 444414 |
| some lesions observed in calves born to cows exposed to the virus of infectious bovine rhinotracheitis in the last trimester of gestation. | sixteen pregnant cows were challenged with infectious bovine rhinotracheitis virus intranasally. one had a mummified fetus, four aborted, one calf was stillborn, two live fetuses were taken at the abattoir and eight calves were born alive. of the eight born alive, five were dead by 12 days of age. four of these had the usual lesions of infectious bovine rhinotracheitis as well as lesions in the intestine and peritoneum and two of the four had a fibrinous pneumonia thought to be caused by aspirat ... | 1978 | 743599 |
| maternal immunity to infectious bovine rhinotracheitis and bovine viral diarrhea viruses: duration and effect on vaccination in young calves. | the immune response to modified live-virus bovine viral diarrhea (bvd) vaccine and infectious bovine rhinotracheitis (ibr) vaccine was examined in calves that had received passive maternal antibodies to these viruses. blood serum samples from vaccinated and control (nonvaccinated) calves were examined for more than 1 year to determine the rate of decline of passive anti-bvd and anti-ibr antibodies and the effect that vaccination had on these antibody titers. the control calves lost their antibod ... | 1978 | 204233 |
| an outbreak of the conjunctival form of infectious bovine rhinotracheitis. | an outbreak of severe conjunctivitis involved approximately 30% of a dairy herd of 118 cattle. infectious bovine rhinotracheitis (ibr) virus was identified by cytopathic effects and fluorescent antibody techniques from conjunctival swabs of affected animals. the disease typically presented as a unilateral ocular disease with systemic signs of pyrexia, inappetance, decreased milk production, and some subsequent abortions. | 1978 | 208813 |
| identification of a herpesvirus isolated from cytomegalovirus-transformed human cells. | human cells transformed by cytomegalovirus and transplanted to athymic nude mice yielded a cytopathic virus, hershey medical center virus, following prolonged in vitro passage of the tumor cells. the virus is a double-enveloped herpesvirus, is sensitive to ether, and is inhibited by iododeoxyuridine. no significant antigenic relationship to herpes simplex virus was detected using herpes simplex virus-immune sera in neutralization and immunofluorescence tests, but indirect immunofluorescence test ... | 1978 | 212591 |
| mechanisms of recovery from herpesvirus infections -a review. | a variety of specific immunological mechanisms have been shown to be effective at neutralizing herpesviruses or destroying herpesvirus infected cells. these include both humoral and cell mediated immune responses or combinations thereof. thus, it is genarlly accepted that humoral immunity is probably responsible for preventing reinfection whereas cellular immunity, mediated by t lymphocytes or by the interaction of antibody and fc receptor bearing cells, is more important in recovery from infect ... | 1978 | 217506 |