Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
extrachromosomal bovine papillomavirus type 1 dna in hamster fibromas and fibrosarcomas. 19816274094
identification of papillomaviruses in butchers' warts.we have studied the papillomaviruses found in the hand warts of 60 butchers, most of them from 2 distant slaughterhouses. warts differing in morphology and location were studied separately. the viruses were identified by molecular hybridization, restriction enzyme analysis and immunofluorescence. four known human papillomaviruses (hpv-1, hpv-2, hpv-3, hpv-4) were detected and one hitherto unknown papillomavirus was identified in 9 butchers. the dna of the latter virus did not anneal with any of ...19816257792
apparent lack of integration of bovine papillomavirus dna in virus-induced equine and bovine tumor cells and virus-transformed mouse cells. 19816258289
bovine papilloma virus deoxyribonucleic acid: a novel eucaryotic cloning vector.a novel eucaryotic vector derived from the transforming region of bovine papilloma virus was established and demonstrated to be highly effective for introducing foreign genes into animal cells. the foreign deoxyribonucleic acid (dna) is replicated and actively transcribed as an episome, and the transcripts are translated into an authentic gene product. we have constructed a dna hybrid molecule, bpv69t-ri1, containing the transforming region of bovine papilloma virus dna and the rat preproinsulin ...19816100967
a new phenomenon (smog) associated with solid phase immune electron microscopy.solid phase immune electron microscopy (spiem) has been used to study the interaction of virus and antibody both quickly and with economy of reagents. unexpectedly, the present study shows that when virus-coated grids are floated on drops of specific antibody the virus particles migrate to form complexes. this has been termed specific migration on the grid (smog) and it is suggested that it can be used both to assess the properties of an antiserum and to make virus more readily detectable. the m ...19806262338
a quantitative in vitro focus assay for bovine papilloma virus. 19806247821
in vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus dna. 19806251381
equine connective tissue tumors contain unintegrated bovine papilloma virus dna.bovine papilloma virus (bpv) appears to be the etiological agent of common equine connective tissue tumors. we investigated the physical state of the viral dna within such tumors and found no indication for integration into the host genome. the bpv genomes were present as free circular episomes. two equine sarcoids were shown to contain multiple copies of free circular bpv type 1 (bpv-1) dna. when the tumors were digested with several single-cut restriction enzymes, there were only form iii bpv- ...19806252350
bracken fern and papilloma virus in bovine alimentary cancer. 19806266569
hybridization of bovine papilloma virus type 1 and type 2 dna to dna from virus-induced hamster tumors and naturally occurring equine tumors.dnas from bovine papilloma virus(bpv)-induced hamster tumors and from equine connective tissue tumors of unknown etiology were examined for bpv dna sequences by molecular hybridization. dna from two distinct classes of bpv (type 1 and type 2) was labeled in vitro and used as probes. analysis of dna-dna reassociation kinetics indicated that both virus types were capable of tumor induction in the hamster. dna isolated from 6 of 7 equine tumors accelerated the reassociation of the bpv dna probes. b ...1979218902
seroepidemiologic studies of bovine papillomavirus infections.bovine and human sera were analyzed for the presence of antibodies against bovine papillomavirus types 1 and 2 (bpv 1 and 2) and human papillomavirus type 1 (hpv 1) in a solid-phase radioimmunoassay. human sera did not react with bpv antigens, and bovine sera showed no evidence of antibodies against hpv 1. in contrast, 19% of all bovine sera tested reacted with bpv 1 and 2 antigens, and 35% of human sera revealed antibodies against hpv 1. no serologic evidence was obtained for heterologous infec ...1979220453
a survey of bovine teat papillomatosis. 1979222039
partial characterization of a new type of bovine papilloma viruses. 1979223295
in vitro transformation by bovine papilloma virus.this paper reports the development of a quantal transformation assay for bovine papillome virus. support for its specificity to fibropapilloma derived bovine papilloma virus comes from (i) the absence of transformation associated changes following inoculations of normal bovine skin, bovine teat papilloma, bovine teat focal epithelial hyperplasia lesion and canine papilloma derived suspensions; (2) in vitro transformation occurs when cscl purified fibropapilloma-derived bpv is used; (3) in vitro ...1979225431
physical maps of bovine papillomavirus type 1 and type 2 genomes.physical maps of bovine papillomavirus type 1 and type 2 (bpv-1 and bpv-2) dna were constructed from analysis of the electrophoretic mobilities of restriction endonuclease cleavage fragments from dual digests. bpv-1 dna was sensitive to hind iii, hindiii, ecori, hpai, and bamhi, with all but hindii yielding single scissions. bpv-2 dna was resistant to ecori, and hindiii had one cleavage site whereas hpai, bamhi, and hindii yielded multiple fragments. of four bpv-1 isolates examined, dna from one ...1979228086
conserved polynucleotide sequences among the genomes of papillomaviruses.the dnas of different members of the papillomavirus genus of papovaviruses were analyzed for nucleotide sequence homology. under standard hybridization conditions (tm - 28 degrees c), no homology was detectable among the genomes of human papillomavirus type 1 (hpv-1), bovine papillomavirus type 2 (bpv-2), or cottontail rabbit (shope) papillomavirus (crpv). however, under less stringent conditions (i.e., tm - 43 degrees c), stable hybrids were formed between radiolabeled dnas of crpv, bpv-1, or b ...1979232171
experimental transmission of bovine papilloma virus (bpv) extracted from morphologically distinct teat and cutaneous lesions and the effects of inoculation of bpv transformed fetal bovine cells.bovine papilloma virus (bpv) was extracted from five cattle each affected with only one of five morphologically distinct lesion types. when inoculated into experimental calves either by scarification or intradermal injection, the bpv extracts produced lesions macroscopically and microscopically similar to those from which individual extracts were made. fetal bovine cells, transformed in vitro with bpv, failed to produce fibromas, fibropapillomas or papillomas when inoculated into experimental ca ...1979233276
the occurrence of human wart-virus antibodies in dogs, pigs and cattle.using the immunodiffusion method, antibodies against human wart-virus were detected in dog, pig and cattle sera but not in horse and reindeer sera. antibodies were found in 25 percent (28/114) of the dog sera, the prevalence of antibodies being fairly similar to that in children of the same age. by electron microscopy the antibodies in dog sera were shown to attach to and precipitate the human wart-virus particles, and in immunodiffusion the precipitation lines of human and dog sera were shown t ...1978210743
demonstration of two distinct classes of bovine papilloma virus. 1978213876
common membrane neoantigens on bovine papilloma virus-induced fibroma cells from cattle and horses.cultured cells from bovine papilloma virus (bpv)-induced fibroblastic tumors and normal dermis of cattle, horses, and hamsters were examined for cell membrane or internal neoantigens, using the indirect immunofluorescence technique. sera from cattle and horses bearing bpv-induced fibromas cross reacted with cell membranes of tumor, but not with normal dermal cells of both species. the reaction could be blocked with homologous, but not heterologous, serum of these 2 species. immunofluorescence wa ...1978213996
chromatin-like structures obtained after alkaline disruption of bovine and human papillomaviruses.four low-molecular-weight polypeptides migrating like h2a, h2b, h3, and h4 calf liver histones were detected by sodium dodecyl sulfate-acrylamide gel electrophoresis of highly purified preparations of bovine papillomavirus (bpv) and human papillomavirus (hpv). complexes of these polypeptides and viral dna were isolated by agarose-gel filtration of the alkaline disruption products of both viruses. when observed under the electron microscope, these complexes appeared as circular structures compose ...1977191643
bovine papilloma virus: presence of virus-specific dna sequences in naturally occurring equine tumors.four of five spontaneous benign equine connective tissue tumors of unknown etiology and a bovine papilloma virus (bpv)-induced equine tumor contained bpv-specific dna sequences as determined by dna-dna hybridization of dna from tumors with bpv dna labeled in vitro. analysis of the kinetics of reassociation indicated that 20-75% of the bpv genome was present in the various tumors. the number of partial bpv genome equivalents ranged from 60 to 500 copies per diploid quantity of cellular dna. therm ...1977191813
quantitation of bovine papilloma viral dna in viral-induced tumors.bovine papilloma virus (bpv) dna was labeled in vitro under conditions of repair synthesis and subsequently used as a "probe" in dna-dna reassociation studies to detect bpv-specific dna sequences in a viral-induced calf meningioma and hamster fibroma. in vitro labeled bpv dna had denaturation characteristics expected for duplex dna and denatured dna reassociated with apparent second-order kinetics. analysis of in vitro labeled bpv dna reassociation rates in the presence of excess tumor dna revea ...1976176447
precipitin response of cattle to commercial wart vaccine.fifty young bulls were given commercial wart vaccine upon their arrival at a bull stud establishment. the bulls were given 2 additional vaccinations 2 and 24 weeks later. the precipitin antibody response of these bulls to bovine papilloma virus was monitored. antibody levels increased significantly, particularly after the 3rd vaccination was given at 24 weeks, but decreased markedly within 20 weeks after the last vaccination was given. these results demonstrated that formalin-inactivated bovine ...1976178253
persistent papillomatosis associated with immunodeficiency.a case report of a young bull with persistent papillomatosis associated with immunodeficiency is presented. humoral immune responses were normal but cell mediated immunity was deficient. the possible significance of the findings to pathogenesis and therapy of the disease is discussed.1975165037
[induction of cutaneous or subcutaneous fibroblastic tumors in the afghan pika (ochotona rufescens rufescens) by injection or bovine papilloma virus].newborn afghan pikas have been inoculated with bovine papilloma virus via the subcutaneous route. cutaneous or subcutaneous fibromas and fibrosarcomas were observed after a mean incubation period of nine months. the transmission of these tumors by homograft has been obtained. bovine papilloma virus antibodies have been demonstrated in most of the animals inoculated at birth. they have not been detected in animals bearing transplanted tumors.1975168982
[bovine viruses and methods for their detection]. 1975169627
Displaying items 1501 - 1527 of 1527