Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| antimicrobial properties of dead sea black mineral mud. | the unique, black, hypersaline mud mined from the dead sea shores is extensively used in mud packs, masks, and topical body and facial treatments in spas surrounding the lake, and in cosmetic preparations marketed worldwide, but little is known about its antimicrobiological properties. | 2006 | 16700781 |
| endogenous endophthalmitis by propionibacterium acnes associated with leflunomide and adalimumab therapy. | to report a case of unusual endogenous endophthalmitis associated with the use of leflunomide and adalimumab. | 2006 | 16703558 |
| a multicenter efficacy and tolerability evaluation of benzoyl peroxide in a 10% urea vehicle for the treatment of acne vulgaris. | acne vulgaris is a common skin disease that affects 70 to 96% of individuals. topical benzoyl peroxide has been used successfully for acne treatment; however, it may be accompanied by drying and or flaking skin. the addition of a 10% urea to the product excipient is theorized to moisturize the skin due to its humectant properties, aid in the efficacy of benzoyl peroxide due to its keratolytic properties, and effectively combat propionibacterium acnes due to its antibacterial properties. | 2006 | 16703780 |
| elimination and multiplication of bacteria during preparation and storage of buffy coat-derived platelet concentrates. | the prevalence of bacterial contamination of random-donor platelet concentrates (pcs) is considerably lower than that of blood donations. which key steps of the preparation procedure contribute to the elimination of bacteria was investigated. | 2006 | 16734811 |
| role of intravitreal triamcinolone acetonide in the treatment of postoperative endophthalmitis. | to report the use of commercially available triamcinolone acetonide as adjunct treatment for acute-onset endophthalmitis after intraocular procedures. | 2006 | 16770261 |
| [biotyping of propionibacterium acnes strains isolated from patients with acne vulgaris]. | propionibacterium acnes is the main bacterial etiologic agent in acne vulgaris pathogenesis. the rate of antibiotic resistant p. acnes isolates is less than 10% in our country. the aim of this study was to biotype p. acnes strains which were isolated from acne vulgaris patients and to investigate the biotype distribution in our region. p. acnes isolates from 64 patients (18 male, 46 female; mean age 19 +/- 3.1 years) were included in the study and biotyped by sugar-specific ph changes using sorb ... | 2006 | 16775952 |
| effect of bacteriocin produced by lactococcus sp. hy 449 on skin-inflammatory bacteria. | this study was carried out to evaluate the effect of bacteriocin produced by lactococcus sp.hy 449 against skin-inflammatory bacteria such as staphylococcus epidermidis atcc 12228, staphylococcus aureus atcc 65389, streptococcus pyogenes atcc 21059, and propionibacterium acnes atcc 6919. the spot-on-the-lawn method was used to determine the antimicrobial activity of bacteriocin against indicator strains on the human skin. the bacteriocin produced by lactococcus sp. hy 449 inhibited the growth of ... | 2006 | 16226831 |
| treatment of acne could lead to the better control of cellular autoimmune disorders. | 2006 | 16253429 | |
| comparative in vitro activities of retapamulin (sb-275833) against 141 clinical isolates of propionibacterium spp., including 117 p. acnes isolates. | using the nccls agar dilution method, we studied the in vitro activity of retapamulin (sb-275833) against 141 clinical isolates of propionibacterium species, including seven multiresistant strains, and found retapamulin to be the most active agent among those tested with mics of < or = 1 microg/ml against all isolates. | 2006 | 16377717 |
| commensal oral bacteria antigens prime human dendritic cells to induce th1, th2 or treg differentiation. | in various immunopathologic conditions, bacterial flora induce an immune response which results in inflammatory manifestations, e.g. periapical granuloma. dendritic cells provide the main orchestration of specific immune responses. the aim of our study was to test the capacity of distinct oral bacterial antigens (prepared from streptococcus mitis, propionibacterium acnes, and bacteroides spp.) to prime human dendritic cells for stimulation of the t-lymphocyte response. to assess the t-lymphocyte ... | 2006 | 16390334 |
| the temperature dependence of porphyrin production in propionibacterium acnes after incubation with 5-aminolevulinic acid (ala) and its methyl ester (m-ala). | topical pdt treatment of the common skin disease acne vulgaris is now in clinical use. propionibacterium acnes (p. acnes) is known to play an important role in acne. 5-aminolevulinic acid (ala) supplementation leads to an enhanced porphyrin production in the bacteria. subsequent illumination with light of the proper wavelengths can reduce the number of bacteria and this might at least partly explain the pdt effect on acne. we have assessed the effects of temperature on p. acnes washed cell suspe ... | 2006 | 16395429 |
| basics of flow cytometry-based sterility testing of platelet concentrates. | flow cytometry (facs) is a common technique in blood banking. it is used, for example, for the enumeration of residual white blood cells in plasma and in cellular blood products. it was investigated whether it can also be applied for sterility testing of buffy coat-derived platelet concentrates (pcs). | 2006 | 16398729 |
| clinical and bacteriological evaluation of nadifloxacin 1% cream in patients with acne vulgaris: a double-blind, phase iii comparison study versus erythromycin 2% cream. | the aim of this double-blind, multinational, phase iii study was to investigate the clinical and bacteriological efficacy of nadifloxacin 1% cream compared with erythromycin 2% cream in 474 european patients with predominantly inflamed slight-to-moderate acne vulgaris. during 12 weeks of treatment both nadifloxacin and erythromycin caused significant reduction in the number of inflamed papulo-pustular lesions (66.7% and 64.7%, respectively) and open and closed comedones. the microbiological eval ... | 2006 | 16436342 |
| the presence of propionibacterium spp. in the vitreous fluid of uveitis patients with sarcoidosis. | 2006 | 16445463 | |
| in vivo and in vitro effect of killed propionibacterium acnes and its purified soluble polysaccharide on mouse bone marrow stem cells and dendritic cell differentiation. | among the effects exerted by propionibacterium acnes, a most relevant one is its capacity to modulate the th1/th2 cellular immune response. this effect depends on the induction and activation of antigen presenting cells, mainly dendritic cells (dcs), whose number is increased in the peripheral blood of animals treated with this bacterium. a soluble p. acnes polysaccharide (ps) extract also acts on dcs, modulating a th1 immune response. these data led us to investigate the role of p. acnes and it ... | 2006 | 16446175 |
| influence of a new surface modification of intraocular lenses with fluoroalkylsilan on the adherence of endophthalmitis-causing bacteria in vitro. | dynasilan is a fluoroalkylsilan that is able to interact with surface active centres on intraocular lenses (iol), offering a new way for surface modification of different iol materials. the purpose of this in vitro study was to investigate the influence of this new surface modification on the adherence of two typical endophthalmitis causing bacteria (staphylococcus epidermidis, propionibacterium acnes). | 2006 | 16453124 |
| production of trans-10, cis-12 conjugated linoleic acid in rice. | conjugated linoleic acid (cla) has anti-carcinogenic and anti-atherosclerosis activity, and modulatory effects on the immune system and lipid metabolism. to produce a transgenic rice plant that can accumulate cla, a linoleate isomerase gene that can convert linoleic acid to trans-10, cis-12 cla was introduced and expressed under the control of seed-specific promoters from the oleosin and globulin genes. the fatty acid composition of the transgenic rice grain was analyzed by gas chromatography. a ... | 2006 | 16475013 |
| structure and mechanism of the propionibacterium acnes polyunsaturated fatty acid isomerase. | conjugated linoleic acids (clas) affect body fat gain, carcinogenesis, insulin resistance, and lipid peroxidation in mammals. several isomers of cla exist, of which the (9z, 11e) and (10e, 12z) isomers have beneficial effects on human metabolism but are scarce in foods. bacterial polyunsaturated fatty acid isomerases are promising biotechnological catalysts for cla production. we describe six crystal structures of the propionibacterium acnes polyunsaturated fatty acid isomerase pai in apo- and p ... | 2006 | 16477020 |
| propionibacterium acnes. | propionibacterium acnes, a common skin organism, is most notably recognized for its role in acne vulgaris. it also causes postoperative and device-related infections and has been associated with a number of other conditions such as sarcoidosis and synovitis, acne, pustulosis, hyperostosis and osteitis (sapho), although its precise role as a causative agent remains to be determined. propionibacterium acnes produces a number of virulence factors and is well known for its inflammatory and immunomod ... | 2006 | 16478502 |
| anterior chamber paracentesis cytology (cytospin technique) for the diagnosis of intraocular lymphoma. | to report on the diagnosis of intraocular lymphoma by aqueous cytology. | 2006 | 16488933 |
| antimicrobial susceptibility of anaerobic bacteria in new zealand: 1999-2003. | routine susceptibility testing of all anaerobic organisms is not advocated, but it is useful for laboratories to test periodically for anaerobic organisms and provide local susceptibility data to guide therapy. this study reports the national trend of antibiotic susceptibility of clinically significant anaerobes in new zealand. | 2006 | 16507560 |
| in-house siras phasing of the polyunsaturated fatty-acid isomerase from propionibacterium acnes. | the polyenoic fatty-acid isomerase from propionibacterium acnes (pai) catalyzes the double-bond isomerization of linoleic acid to conjugated linoleic acid, which is a dairy- or meat-derived fatty acid in the human diet. pai was overproduced in escherichia coli and purified to homogeneity as a yellow-coloured protein. the nature of the bound cofactor was analyzed by absorption and fluorescence spectroscopy. single crystals of pai were obtained in two crystal forms. cubic shaped crystals belong to ... | 2006 | 16511289 |
| long-chain 3-acyl-4-hydroxycoumarins: structure and antibacterial activity. | by reacting 4-hydroxycoumarin with long-chain acyl chlorides, a number of new 3-acyl derivatives were prepared and the relationship was studied between their structures and activities against staphylococcus aureus atcc 6538, staphylococcus epidermidis atcc 12228, and propionibacterium acnes atcc 11827. antibacterial activity was associated with enolic tautomers of a tricarbonylmethane group bearing a lipophilic side chain (undec-10-enoyl, undec-10-ynoyl, palmitoyl or octadec-9-enoyl). a newly sy ... | 2006 | 16511806 |
| gene array expression profiling in acne lesions reveals marked upregulation of genes involved in inflammation and matrix remodeling. | the pathogenesis of acne has been linked to multiple factors such as increased sebum production, inflammation, follicular hyperkeratinization, and the action of propionibacterium acnes within the follicle. in an attempt to understand the specific genes involved in inflammatory acne, we performed gene expression profiling in acne patients. skin biopsies were obtained from an inflammatory papule and from normal skin in six patients with acne. biopsies were also taken from normal skin of six subjec ... | 2006 | 16528362 |
| improved aero-anaerobe recovery from infected prosthetic joint samples taken from 72 patients and collected intraoperatively in rosenow's broth. | recovery of the bacteria responsible for prosthetic joint infections is a major problem, which is due in part to the alteration of their ability to grow by storage during transportation to the laboratory. | 2006 | 16534711 |
| anti-inflammatory activity of cationic peptides: application to the treatment of acne vulgaris. | cationic antimicrobial peptides exhibit potent antimicrobial activity against clinically relevant microorganisms including propionibacterium acnes. recent studies showed that, in addition to the antimicrobial activity, these peptides can exhibit an anti-inflammatory effect. these properties make cationic peptides attractive drug candidates for the treatment of acne vulgaris, a disease with both bacterial and inflammatory components. this review focuses on the anti-inflammatory activity of cation ... | 2006 | 16553825 |
| partial posterior capsulectomy through an anterior approach: an intraocular lens retaining technique in the management of presumed propionibacterium acnes endophthalmitis. | 2006 | 15746949 | |
| evaluation of in vitro antimicrobial activity of thai basil oils and their micro-emulsion formulas against propionibacterium acnes. | the aim of this study was to evaluate the efficacy of thai basil oils and their micro-emulsions, on in vitro activity against propionibacterium acnes. an agar disc diffusion method was employed for screening antimicrobial activity of the essential oils of ocimum basilicum l. (sweet basil), ocimum sanctum l. (holy basil) and ocimum americanum l. (hoary basil) against p. acnes. minimum inhibitory concentration (mic) values of the basil oils were determined using an agar dilution assay. the obtaine ... | 2006 | 18492147 |
| antimicrobial susceptibility of strains of propionibacterium acnes isolated from inflammatory acne. | in the last decade, a significant increase in the antimicrobial resistance of clinical specimens of propionibacterium acnes to first line antibiotics used for acne treatment, has been informed in europe and in the usa. no information about strains isolated from latin-american countries is available. the antimicrobial susceptibility of 53 strains of p. acnes isolated from skin specimens of inflammatory acne patients, at the clinical hospital university of chile was tested. all isolates were susce ... | 2006 | 17357569 |
| the infectivity of sarcoid clinical material and its bacterial content inoculated in cba mice. | sarcoidosis is a multisystemic disorder that is currently viewed as the consequence of chronic immunological response associating genetic susceptibility and specific environmental or transmissible agents. relevant evidence, although conflicting, justifies a concern about the involvement of specific pathogens to disease causation. in this study we assessed the infectivity of sarcoid clinical material, and of the pathogens found in it, to normal cba mice used as a model of an immuno-competent host ... | 2006 | 17203772 |
| nasal antibiotic-resistant propionibacterium acnes carriage in acne vulgaris patients in turkey. | 2006 | 17169100 | |
| therapeutic blue light: a different ray of light on an age-old problem. | 2006 | 17199464 | |
| in vitro bactericidal effects of 405-nm and 470-nm blue light. | the aim of this study was to determine the bactericidal effect of 405- and 470-nm light on two bacteria, staphylococcus aureus and pseudomonas aeruginosa, in vitro. | 2006 | 17199466 |
| [identification of propionibacterium acnes in a case with stage iii pulmonary sarcoidosis involving hepatosplenic disease]. | a 35-year-old woman was admitted to our hospital because of an abnormal chest radiograph. chest x-ray on admission showed multiple small nodular shadows in both lung fields but no bilateral hilar lymphadenopathy (bhl). moreover, abdominal ct showed some nodules in the liver and spleen, and serum ace was slightly increased to 23.3u/l (normal range: 8.3-21.4u/l). transbronchial lung biopsy and liver biopsy resulted in a diagnosis of stage iii pulmonary sarcoidosis with hepatosplenic disease. histo ... | 2006 | 17037406 |
| inhibition of propionibacterium acnes by bacteriocin-like inhibitory substances (blis) produced by streptococcus salivarius. | we report the in vitro inhibition of propionibacterium acnes (p. acnes) by a bacteriocin-like inhibitory substance (blis-like substance) produced by streptococcus salivarius (s. salivarius). bacteriocins are proteinaceous substances produced by bacteria that are capable of inhibiting the growth of similar bacterial strains. unlike classical antibiotics, they have a relatively narrow spectrum of killing activity, resulting in a reduction in the intensity of selection for resistance. these finding ... | 2006 | 17039652 |
| propionibacterium acnes infections after cranial neurosurgery. | propionibacterium acnes (p. acnes) is a relatively avirulent organism that is part of the normal skin flora. most patient isolates are considered contaminants but, in a small subset of patients, particularly in the post-neurosurgery setting, the organism can cause significant infections. we reviewed our experience with the occurrence and management of p. acnes infections after cranial neurosurgical procedures over a five-year period. | 2006 | 17001816 |
| association between the presence of bacterial 16s rna in prostate specimens taken during transurethral resection of prostate and subsequent risk of prostate cancer (sweden). | to study bacterial 16s rna in archival prostate samples from 352 patients with benign prostate hyperplasia (bph) and evaluate whether the presence of bacterial dna was different in those who later developed prostate cancer (n = 171) and in the matched controls that did not progress to cancer (n = 181). | 2006 | 17006718 |
| systemic antibiotic therapy of acne vulgaris. | inflammatory, medium to severe acne vulgaris is treated with systemic antibiotics worldwide. the rationale is an effect on propionibacterium acnes as well as the intrinsic anti-inflammatory properties of these antibiotics. although there are no correlations between the number of p. acnes and the severity of the disease, associations between the degree of humoral and cellular immune responses towards p. acnes and the severity of acne have been reported. exact data on practical use of these compou ... | 2006 | 17010172 |
| acne: more than skin deep. | acne is one of the most prevalent skin conditions affecting teenagers. it is a disease of the pilosebaceous unit. blockage of sebaceous glands and colonisation with proionobacterium acnes leads to acne. grading the severity of acne helps to determine the appropriate treatment. treatment of acne should be started as early as possible to minimise the risk of scarring and adverse psychological effects. it should be tailored to the individual patient, the type of acne, its severity, the patient's ab ... | 2006 | 16891439 |
| corrosion and late infection causing delayed paraparesis after spinal instrumentation. | a 28-year-old female patient came to our hospital 14 years after surgical correction of adolescent idiopathic scoliosis with a 316l stainless-steel instrumentation. she presented progressive paraparesis during the last 2 months. plain radiography, computed tomography scan and computed tomography-scan-guided needle biopsy revealed that a metallotic mass penetrated into the spinal canal, causing compression of the spinal cord at the t5-t6 level. the patient's symptoms were related to corrosion of ... | 2006 | 16891957 |
| delayed posttraumatic propionibacterium acnes endophthalmitis in a child. | a 7-year-old boy presented with granulomatous anterior uveitis after an unrecognized penetrating injury in the same eye 2 months previously. the uveitis was unresponsive to topical corticosteroid therapy, lensectomy with anterior vitrectomy, and administration of intraocular and subconjunctival injections of vancomycin. pars plana vitrectomy, capsulectomy, and injection of intravitreal vancomycin were eventually performed, leading to complete resolution of the intraocular inflammation. culture a ... | 2006 | 16898393 |
| evaluation of cytokines concentration and percentage of survival of rabies virus-infected mice submitted to anti-rabies vero-cell propagated vaccine and p. acnes. | previously, survival of rabies infection was shown to correlate with low il-6 serum concentration in mice subjected to post-exposure treatment with the fuenzalida palacios rabies vaccine in conjunction with the immunomodulator propionibacterium acnes, previously corynebacterium parvum. considering the substitution of the fuenzalida palacios rabies vaccine by the vero cell raised anti-rabies vaccine in almost all countries, the objective of this work was to evaluate the survival and cytokine seru ... | 2006 | 16930720 |
| critical role of toll-like receptors and the common tlr adaptor, myd88, in induction of granulomas and liver injury. | toll-like receptors (tlr) recognize pathogens and regulate innate immune activation. here, we investigated the roles of tlr9 and the common tlr adaptor, myd88, in liver injury. | 2006 | 16935388 |
| sarcoidosis and nod1 variation with impaired recognition of intracellular propionibacterium acnes. | sarcoidosis is a systemic granulomatous disease of unknown etiology. nod2 mutations have been shown to predispose to granulomatous diseases, including crohn's disease, blau syndrome, and early-onset sarcoidosis, but not to adult sarcoidosis. we found that intracellular propionibacterium acnes, a possible causative agent of sarcoidosis, activated nf-kappab in both nod1- and nod2-dependent manners. systematic search for nod1 gene polymorphisms in japanese sarcoidosis patients identified two allele ... | 2006 | 16935475 |
| outbreak of postoperative shoulder arthritis due to propionibacterium acnes infection in nondebilitated patients. | we investigated an outbreak of postoperative shoulder arthritis due to propionibacterium acnes infection in nondebilitated patients. risk factors were male sex, the order in which surgery was performed during the daily operating schedule, and increased duration of the surgical procedure. after modification of the ventilation system and implementation of improved cleaning methods in the operating theater, no new cases were recorded. | 2006 | 16941330 |
| investigation of the mechanism of action of nonablative pulsed-dye laser therapy in photorejuvenation and inflammatory acne vulgaris. | nonablative lasers are widely used for treatment of wrinkles, atrophic scars and acne. these lasers stimulate dermal remodelling and collagen production, but the early molecular stimulus for this is unknown. the mechanism of nonablative lasers in inflammatory acne is variously suggested to be damage either to sebaceous glands or to propionibacterium acnes. their effects on cytokine production are unknown. | 2006 | 16965424 |
| essential roles of dc-derived il-15 as a mediator of inflammatory responses in vivo. | interleukin (il)-15 is expressed in a variety of inflammatory diseases. however, the contribution of dendritic cell (dc)-derived il-15 to the development of diseases is uncertain. using established models of propionibacterium acnes (p. acnes)- and zymosan-induced liver inflammation, we observed granuloma formation in the livers of wild-type (wt) and rag-2(-/-) mice but not in those of il-15(-/-) mice. we demonstrate that this is likely caused by an impaired sequential induction of il-12, ifn-gam ... | 2006 | 16966429 |
| susceptibilities of propionibacterium acnes ophthalmic isolates to ertapenem, meropenem, and cefepime. | we investigated the in vitro susceptibilities of 23 propionibacterium acnes ophthalmic isolates to ertapenem, meropenem, and cefepime by utilizing the etest. the mics ranged from 0.094 microg/ml to 0.75 microg/ml, 0.094 microg/ml to 1.5 microg/ml, and 1 microg/ml to 12 microg/ml for ertapenem, meropenem, and cefepime, respectively. based on our excellent in vitro carbapenem susceptibility results, in vivo studies using ertapenem and meropenem in a rabbit model of p. acnes endophthalmitis are war ... | 2006 | 16971643 |
| treatment considerations for inflammatory acne: clinical evidence for adapalene 0.1% in combination therapies. | acne vulgaris is an exceptionally common, chronic, and recurring disease. it involves multiple etiological factors including follicular hyperkeratinization, increased sebum production, propionibacterium acnes proliferation, and inflammation. presently, oral isotretinoin is the only single agent that is effective against all 4 major pathophysiologic features. however, this drug is also responsible for several serious side effects, including teratogenicity. therefore, it should be used in only the ... | 2006 | 16989194 |
| pharmacological management of sapho syndrome. | the sapho (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome (sas) includes different skeletal manifestations such as recurrent multifocal osteomyelitis, osteitis and arthritis, which are frequently associated with different forms of skin pustulosis (palmoplantar pustulosis, pustular psoriasis and severe acne). this syndrome is strictly related to the spondyloarthopathies (particularly to psoriatic arthritis) and many sas cases fulfil the classification criteria for the spondyloar ... | 2006 | 16989598 |
| antibiotic resistance in propionibacterium acnes. microbiological and clinical aspects. | 2006 | 17000123 | |
| propionibacter acnes complicating hiv-associated tuberculous pericardial effusion in cameroon. | large pericardial effusions are common in sub-saharan africa. they are most often caused by tuberculosis and are frequently associated with hiv infection. we report on a case of massive pericardial effusion in a 32-year-old hiv-positive male with smear-positive pulmonary tuberculosis. this was found to be colonised by propionibacter acnes, which is normally found in anaerobic skin flora. despite management, including appropriate antibiotic treatment based on culture and sensitivity, the patient ... | 2006 | 17117231 |
| [the influence of amps from hacat keratinocytes on some bacteria strains derived from skin changes]. | the aim of this study was to evaluate antimicrobial activity of protein extracts from hacat cell line against bacterial strains, isolated from clinical materials, obtained from patients with clinical symptoms of acne (propionibacterium acnes) and gas gangrene (clostridium perfringens and sterptococcus pyogenes). reference strain of staphylococcus aureus atcc 25923 also was used. protein extracts from cultured hacat cells were obtained by 3-fold freezing/defreezing cells in dry ice following by c ... | 2006 | 17133910 |
| bacteraemia in patients with hidradenitis suppurativa undergoing carbon dioxide laser surgery: detection and quantification of bacteria by lysis-filtration. | hidradenitis suppurativa (hs) is a cicatrising and persistent disease of apocrine gland-bearing areas in adults. the severity of this condition varies from a few suppurating lesions to widespread, disabling disease. the aetiology is obscure, but suggested contributory factors include a genetic predisposition, comedones occluding the pilosebaceous apparatus, bacterial infections, and hormonal factors. treatment consists mainly of surgery, while medical therapies serve principally as adjunct thera ... | 2006 | 17135736 |
| variable expression of immunoreactive surface proteins of propionibacterium acnes. | despite accumulating data implicating propionibacterium acnes in a variety of diseases, its precise role in infection remains to be determined. p. acnes antigen-specific cd4(+) t cells are present in early inflamed acne lesions and may be involved in the inflammatory response; however, little is known about the specific antigens involved. in this study, b cell and t cell antigens from p. acnes expression libraries were cloned and evaluated and the four predominant proteins identified were invest ... | 2006 | 17159220 |
| re: propionibacterium acnes infections after cranial neurosurgery. can j neurol sci. 2006;33:292-5. | 2006 | 17168177 | |
| inhibition of pathogenic bacterial adhesion by acidic polysaccharide from green tea (camellia sinensis). | an acidic polysaccharide cs-f2 from camellia sinensis was examined to characterize its anti-adhesive effects against pathogenic bacteria, most notably helicobacter pylori, propionibacterium acnes, and staphylococcus aureus. cs-f2 showed marked inhibitory activity against the pathogen-mediated hemagglutination with a minimum inhibitory concentration (mic) between 0.01 and 0.1 mg/ml, which is lower than the previously reported mic values for panax ginseng and artemisia capillaris. the inhibitory e ... | 2006 | 17090112 |
| bacterial diversity in aortic aneurysms determined by 16s ribosomal rna gene analysis. | aortic aneurysms are common vascular conditions that cause considerable morbidity and mortality. understanding of the mechanisms involved in the pathogenesis of the condition remains limited. recently, infection has been suggested as possible contributor in the development of the disease. the aim of the present study was to examine aortic aneurysms for the presence of bacterial dna using polymerase chain reaction (pcr) targeting the 16s ribosomal rna (rrna) gene, followed by cloning and sequenci ... | 2006 | 17098542 |
| bacteriology of chronic sinusitis and acute exacerbation of chronic sinusitis. | to establish the microbiological characteristics of acute exacerbation of chronic sinusitis (aecs). | 2006 | 17043258 |
| neurological picture. production of oil in a brain abscess caused by propionibacterium acnes. | 2006 | 17043293 | |
| microbial contamination of "in use" bar soap in dental clinics. | bar soap from 18 different dental clinics were investigated for microbial contamination, while it was "in-use". of the 32 samples obtained from the bar soap, 100% yielded positive culture. a total of 8 different genera of organisms were isolated. each bar soap was found to harbor 2-5 different genera of micro organisms. heavily used soap had more micro organisms compared to less used soap. the microbial load of the "in-use" bar soap constituted a mixed flora of gram positive, gram negative, aero ... | 2006 | 17051871 |
| benzoyl peroxide/clindamycin/uva is more effective than fluticasone/uva in progressive macular hypomelanosis: a randomized study. | there is no effective treatment for progressive macular hypomelanosis. recent findings indicate that propionibacterium acnes may play a role in the pathogenesis. | 2006 | 17052490 |
| treatment of active acne with an er:glass (1.54 microm) laser: a 2-year follow-up study. | to investigate the effects of the 1.54 microm wavelength on active lesions of the face and of the back at the 2-year follow-up. | 2006 | 19839169 |
| light/laser therapy in the treatment of acne vulgaris. | acne vulgaris is one of the most prevalent skin diseases known. as common as this condition is, the social and psychological consequences are limitless. although current treatments are available and include topical or oral antibiotics, it is crucial to develop a less risky and more effective therapy such as light/laser therapy. this article focuses specifically on the benefits of the light/laser treatment on acne vulgaris. porphyrins accumulated in the bacteria, propionibacterium acnes, one of t ... | 2005 | 17168883 |
| a case of nodular-type muscular sarcoidosis: findings of imaging, histopathology, and polymerase chain reaction. | we report a case of nodular-type muscular sarcoidosis with no systemic symptoms. thallium-201 scintigraphy showed intense uptake in the muscular lesion mimicking malignant soft tissue tumor. magnetic resonance imaging (mri) demonstrated characteristic signal patterns of peripheral high intensity with central low intensity ("three stripes" pattern). microscopy revealed sarcoid granuloma with typical histopathological characteristics. propionibacterium acnes was detected on polymerase chain reacti ... | 2005 | 17029046 |
| the potential immunomodulatory effects of topical retinoids. | new research has refined our understanding of the immunopathophysiology of acne. various immune factors, including both innate and adaptive immune responses, have been implicated in the pathophysiology of inflammatory acne. topical retinoids such as tretinoin, adapalene, and tazarotene, exhibit immunomodulatory effects that may help to explain their efficacy in the resolution of inflammatory lesions. | 2005 | 15748544 |
| exacerbation of granuloma formation in il-1 receptor antagonist-deficient mice with impaired dendritic cell maturation associated with th2 cytokine production. | dendritic cell (dc) maturation at the site of inflammation and migration into draining lymph nodes is fundamental to initiate ag-specific immune responses. although several proinflammatory cytokines, including il-1, are known to promote dc maturation in vitro, their contributions to dc activation and migration within peripheral inflamed tissue compartments are not yet fully understood. we show here that endogenous il-1 receptor antagonist (il-1ra) controls the activation state of liver-recruited ... | 2005 | 15749858 |
| a case of renal sarcoidosis with complement activation via the lectin pathway. | a 57-year-old woman with pulmonary sarcoidosis was admitted to the hospital because of an elevation of serum creatinine and blood urea nitrogen. on admission, the laboratory data suggested interstitial nephritis without proteinuria and hematuria, whereas a renal biopsy showed granulomatous interstitial nephritis and mild mesangial proliferative glomerulonephritis. immunoglobulin and c1q deposits were negative, but mannose-binding lectin, c3, c4d, and c5b-9 deposits were marked in the glomerular ... | 2005 | 15754281 |
| anaerobic spondylodiscitis: case series and systematic review. | bacterial spondylodiscitis is rarely caused by anaerobic organisms. we describe two patients with lumbar vertebral osteomyelitis and discitis caused by anaerobic bacteria, including an unusual occurrence after an endodontic procedure, and review the salient clinical features and outcomes of 31 previously reported cases. | 2005 | 15759942 |
| different pro-inflammatory and immunogenic potentials of propionibacterium acnes and staphylococcus epidermidis: implications for chronic inflammatory acne. | propionibacterium acnes (pa) and staphyloccocus epidermidis (se) are two major bacterial strains isolated from acne lesions. nevertheless, only pa seems to be implicated in the pathogenesis of inflammatory acne vulgaris. evidence for this, however, remains indirect and the precise role of pa in inflammatory acne is still a matter for conjecture. the aim of this study was to compare some pro-inflammatory and adjuvant properties of pa and se. | 2005 | 15761379 |
| requirement for tlr9 in the immunomodulatory activity of propionibacterium acnes. | propionibacterium acnes (formerly corynebacterium parvum) is part of the human flora and, as such, is associated with several human pathologies. it possesses strong immunomodulatory activities, which makes this bacterium interesting for prophylactic and therapeutic vaccination. the bacterial component(s) and the host receptor(s) involved in the induction of these activities are poorly understood. we show in this study that tlr9 is crucial in generating the characteristic effects of killed p. acn ... | 2005 | 15778393 |
| the pathogenesis of acne. | acne vulgaris is a multifactorial disease of as yet incompletely elucidated etiology and pathogenesis. the following have been identified as the most significant factors: follicular hyperkeratosis, increased sebum secretion, propionibacterium (p.) acnes, and inflammation. increased sebum production and follicular hyperkeratosis result in the development of microcomedones, and changes in follicular milieu in intensive growth of p. acnes. p. acnes secretes several proinflammatory products, which p ... | 2005 | 15788147 |
| acne vulgaris: a review of antibiotic therapy. | antibiotic therapy has been integral to the management of inflammatory acne vulgaris for many years. systemic antibiotics work via antibacterial, anti-inflammatory and immunomodulatory modes of action, and have been found to be useful in managing moderate-to-severe acne. commonly prescribed antibiotics include tetracyclines, erythromycin and trimethoprim, with or without sulfamethoxazole. in selecting the appropriate antibiotic for patients needing to receive topical or systemic antibiotic thera ... | 2005 | 15794732 |
| nadifloxacin, an antiacne quinolone antimicrobial, inhibits the production of proinflammatory cytokines by human peripheral blood mononuclear cells and normal human keratinocytes. | acne vulgaris is a chronic inflammatory disease involving colonization of propionibacterium acnes (p. acnes), activation of neutrophils and lymphocytes. circumstantial evidence suggests that antigen-independent and -dependent immune responses against p. acnes are involved in the pathogenesis of inflammatory acne. epidermal keratinocytes are also suggested to be involved in initiation and progression of cutaneous inflammation. nadifloxacin, a fluorinated quinolone, has potent antimicrobial activi ... | 2005 | 15795123 |
| formulation and evaluation of an effective ph balanced topical antimicrobial product containing tea tree oil. | the effect of ph on the antimicrobial activity of melaleuca alternifolia essential oil formulations was studied. microemulsions, liposomal dispersions, multiple emulsions and a colloidal bed of sterile clay were formulated using 5% w/w of tea tree oil. a number of formulations were prepared at various ph values (5.0, 5.5, 6.0, 6.5, and 7.0). thermal stability studies showed that the formulations were stable for more than eight months. agar dilution tests showed mics of 1.0% v/v s. aureus and s. ... | 2005 | 15801675 |
| incidence of bacteremia after routine tooth brushing. | the american heart association first developed recommendations on antibiotic prophylaxis against infective endocarditis during dental procedures more than 50 years ago. these recommendations were partly based on the fact that bacteremia occurs with dental procedures. previous studies in the 1970s and earlier demonstrated that patients become bacteremic after tooth brushing. improved culture techniques suggest that these rates could be higher now. the objective of this study was to determine the ... | 2005 | 15832100 |
| late implant infections caused by propionibacterium acnes in scoliosis surgery. | one hundred and one consecutive adolescent scoliosis patients instrumented from the posterior between 1995 and 2002, with a minimum follow-up of 24 months (maximum 106 months), were reviewed for incidence of infection. stainless steel implants with pedicle screws were used in the thoracic and lumbar spine of all patients. all were operated on by a single surgeon. there were no early infections. incidence of late infection was 6.9% (seven patients). clinical indicators for infection were the sudd ... | 2005 | 15841406 |
| distinct strains of propionibacterium acnes induce selective human beta-defensin-2 and interleukin-8 expression in human keratinocytes through toll-like receptors. | acne is a chronic inflammatory disease of the pilosebaceous follicle. one of the main pathogenetic factors in acne is the increased proliferation of propionibacterium acnes (p. acnes) in the pilosebaceous unit. we investigated whether direct interaction of p. acnes with keratinocytes might be involved in the inflammation and ductal hypercornification in acne. the capacities of different p. acnes strains to activate the innate immune response and the growth of cultured keratinocytes were investig ... | 2005 | 15854033 |
| anti-inflammatory effects of magnolol and honokiol are mediated through inhibition of the downstream pathway of mekk-1 in nf-kappab activation signaling. | propionibacterium acnes, an anaerobic pathogen, plays an important role in the pathogenesis of acne and seems to initiate the inflammatory process by producing proinflammatory cytokines. in order to demonstrate the anti-inflammatory effects and action mechanisms of magnolol and honokiol, several methods were employed. through dpph and sod activity assays, we found that although both magnolol and honokiol have antioxidant activities, honokiol has relatively stronger antioxidant activities than ma ... | 2005 | 15856410 |
| camp factor homologues in propionibacterium acnes: a new protein family differentially expressed by types i and ii. | analysis of the draft genome sequence of the opportunistic pathogen propionibacterium acnes type strain nctc 737 (=atcc 6919) revealed five genes with sequence identity to the co-haemolytic christie-atkins-munch-peterson (camp) factor of streptococcus agalactiae. the predicted molecular masses for the expressed proteins ranged from 28 to 30 kda. the genes were present in each of the three recently identified reca-based phylogenetic groupings of p. acnes (ia, ib and ii), as assessed by pcr amplif ... | 2005 | 15870447 |
| propionibacterium acnes associated with inflammation in radical prostatectomy specimens: a possible link to cancer evolution? | inflammation is commonly observed in the prostate gland and has been implicated in the development of prostate cancer. the etiology of prostatic inflammation is unknown. however, the involvement of a carcinogenic infectious agent has been suggested. | 2005 | 15879794 |
| propionibacterium acnes is the most common bacterium commensal in peripheral lung tissue and mediastinal lymph nodes from subjects without sarcoidosis. | in studies of the unknown etiology of sarcoidosis, propionibacterium acnes (a possible agent) was found in the lungs and lymph nodes of many sarcoidosis patients and some control subjects. p. acnes might be commensal not only to the skin, conjunctivae, and intestine, but also to the lungs and lymph nodes of individuals without sarcoidosis. | 2005 | 15881278 |
| microbial changes in conjunctival flora with 30-day continuous-wear silicone hydrogel contact lenses. | to determine the effect of 30-day continuous-wear silicone hydrogel contact lenses on the conjunctival flora in asymptomatic wearers. | 2005 | 15894879 |
| mechanism-based treatment of acne vulgaris: the value of combination therapy. | acne vulgaris has multiple pathogenic mechanisms that act in concert to produce disease. effective therapy addresses more than one pathogenic factor to speed resolution of disease. typically, retinoids are used to inhibit comedo formation and an antibacterial is used to suppress propionibacterium acnes (p. acnes). using combinations of agents can enhance efficacy, but increase side effects. therefore, the tolerability of a topical retinoid is important. strategies to enhance retinoid tolerabilit ... | 2005 | 15898282 |
| propionibacterium acnes-induced hepatic granuloma formation is impaired in mice lacking tetraspanin cd9. | the granuloma is a host defence response to persistent pathogenic irritants. in the process of granuloma formation, the activation, migration, and fusion of macrophages occur locally, but the mechanisms involved remain elusive. tetraspanins regulate cell migration and fusion by organizing functional molecular complexes in membrane microdomains. here we investigated the role of tetraspanin cd9 in hepatic granuloma formation. immunostaining of the liver of untreated wild-type mice showed that cd9 ... | 2005 | 15902693 |
| endophthalmitis following cataract surgery in southwest finland from 1987 to 2000. | to investigate the incidence, causes, prevention, treatment and outcome of postoperative endophthalmitis (poe) following cataract surgery in southwest finland from 1987 to 2000. | 2005 | 15906062 |
| effect of zinc gluconate on propionibacterium acnes resistance to erythromycin in patients with inflammatory acne: in vitro and in vivo study. | tetracyclines and macrolide antibiotics have been in use for acne treatment for more than 20 years. since 1992 increasing resistance to these antibiotics, and especially to erythromycin, is reported with propionibacterium acnes. zinc salts have demonstrated their efficacy in inflammatory acne treatment as well as their bacteriostatic activity against propionibacterium acnes. the objective of our work was firstly to determine whether the clinical anti-inflammatory efficacy of zinc salts was alter ... | 2005 | 15908296 |
| infected neonatal cephalohematomas caused by anaerobic bacteria. | to present the microbiological and clinical features of six children with infected cephalohematomas (ic) caused by anaerobic bacteria. | 2005 | 15914351 |
| microbial contamination of hematopoietic progenitor cell grafts-incidence, clinical outcome, and cost-effectiveness: an analysis of 735 grafts. | screening of progenitor cell grafts (marrow, peripheral blood, and cord blood) for microbial contamination is required by the standards of aabb. clinical sequelae from infusion of these contaminated grafts, however, is uncommon. | 2005 | 15934984 |
| postoperative discitis due to propionibacterium acnes: a case report and review of the literature. | no previous report has described a progressive, destructive postoperative discitis requiring operative stabilization due to propionibacterium acnes. the clinical and radiographic features and treatment options associated with discitis due to p acnes are presented in a retrospective case study, as well as a review of the current literature. | 2005 | 15936379 |
| induction of interferon-gamma (ifn-gamma) and t helper 1 (th1) immune response by bitter gourd extract. | mice were inoculated intraperitoneally wih 34 different types of vegetable juices, and interferon-gamma (ifn-gamma) and interleukin-4 (il-4) were measured as markers for the induction of th1 and th2 cells, respectively. serum ifn-gamma level was markedly increased in mice inoculated with bitter gourd (momordica charantia) juice, but il-4 levels were not increased with any of the 34 vegetable juices. testing of the various components of bitter gourd, including peel, pulp, and seed, showed that th ... | 2005 | 15942138 |
| the presence of propionibacterium spp. in the vitreous fluid of uveitis patients with sarcoidosis. | an immunological reaction to a bacterial antigen, such as mycobacterium tuberculosis or propionibacterium spp., is suspected to be an initial mechanism in the disorder known as sarcoidosis. we investigated whether or not p. acnes, p. granulosum or m. tuberculosis are present in the vitreous fluid of eyes suffering from uveitis with sarcoidosis. | 2005 | 15948792 |
| phlyctenular keratitis associated with meibomitis in young patients. | to describe the unique clinical features of phlyctenular keratitis, including the association with meibomitis, in young patients. | 2005 | 15953578 |
| [subacute subdural empyema]. | 2005 | 15970172 | |
| the antimicrobial activities of psidium guajava and juglans regia leaf extracts to acne-developing organisms. | this study aims to present the in vitro inhibitory effect of psidium guajava and juglans regia leaf extracts on the main developer of acne lesions, propionibacterium acnes (p. acnes), and other organisms that are isolated from acne lesions. thirty-eight subjects (males and females) who had various types of acne were enrolled in the study. the contents of the acne lesions were cultured and the frequency of p. acnes (alone and with staphylococci spp.) was 47%, whereas the frequencies for staphyloc ... | 2005 | 15974479 |
| helicobacter pylori accumulates photoactive porphyrins and is killed by visible light. | helicobacter pylori colonizes the mucus layer of the human stomach and duodenum, causes chronic gastritis, gastric ulcer, and is a risk factor for gastric adenocarcinoma. there is a 20% failure rate in antibiotic therapy, which is increasingly due to antibiotic resistance and necessitates the search for alternative antimicrobial methods. we have discovered that h. pylori when cultured in liquid medium, accumulates significant quantities of coproporphyrin and protoporphyrin ix, both in the cells ... | 2005 | 15980355 |
| [oral clarithromycin as a treatment option in chronic post-operative endophthalmitis]. | to assess the outcome of medical treatment with oral clarithromycin in patients with chronic post-surgical endophthalmitis. | 2005 | 15986274 |
| superoxide dismutase and myeloperoxidase activities in polymorphonuclear leukocytes in acne vulgaris. | acne vulgaris frequently occurs in the second decade of life. the pathogenesis of the disease is multifactorial and in the present study, we aimed to investigate the role of reactive oxygen species in the inflammation of acne by determining the activities of myeloperoxidase (mpo) and superoxide dismutase (sod) in polymorphonuclear leukocytes (pmn). | 2005 | 16001098 |
| repeat infective endocarditis: differentiating relapse from reinfection. | repeat infective endocarditis due to the same species can represent relapse of the initial infection or a new infection. we used time-based clinical criteria and pulsed-field gel electrophoresis-based molecular criteria to classify 13 cases of repeat infective endocarditis as either relapse or reinfection. the agreement between clinical and molecular criteria was imperfect (agreement in 10 [77%] of 13 cases). | 2005 | 16007540 |
| antimicrobial effects of thai medicinal plants against acne-inducing bacteria. | propionibacterium acnes and staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. the present study was conducted to evaluate antimicrobial activities of thai medicinal plants against these etiologic agents of acne vulgaris. crude extracts were tested for antimicrobial activities by disc diffusion and broth dilution methods. the results from the disc diffusion method showed that 13 medicinal plants could inhibit the growth of propionibacteriu ... | 2005 | 16009519 |