Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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[an epidemic of q fever on kerguelen islands; problem of retrospective diagnosis]. | 2013 | 13536750 | |
[pseudogrippal syndromes from dakar; q fever]. | 2013 | 13585048 | |
[the second case of autochthonous q fever lorraine]. | 2013 | 13585030 | |
[1st clinical case report of q fever serologically confirmed from madagascar]. | 2013 | 13671322 | |
[experimental rickettsial infection of testudo mauritanica with r. burneti and infection of the tick hyalomma aegyptium]. | 2013 | 13801286 | |
[cardiovascular complications due to q fever and other ricketsioses]. | 2013 | 14113485 | |
[the laboratory diagnosis of q fever and the problem of the antigenic variation of c. burneti]. | 2013 | 14108520 | |
[epidemiology of q fever in italy]. | 2013 | 14108516 | |
[the rickettsioses in central africa]. | 2013 | 14108512 | |
[epidemic of q fever in tul'ear (republic of madagascar)]. | 2013 | 14184775 | |
[clinical aspects of q fever]. | 2013 | 613411 | |
[endemic zoonosis in mediterranean area]. | the mediterranean is historically considered an area of high concentration of zoonoses. mediterranean countries socio-economic features have favoured, over time, the onset of different types of zoonosis. many of these may affect many occupational categories, first of all farmers, people working in abattoirs and processing products of animal origin. new farming activities and technologies have generated new occupational and zoonotic risks. these changes have influenced zoonosis epidemiology and h ... | 2013 | 24303725 |
q fever outbreaks in poland during 2005-2011. | q fever is a health problem affecting humans and animals worldwide. in poland, previous studies have pointed to 2 sources of outbreaks of the disease: the importation of infected animals and their products, and natural domestic foci. in the last decade, 5 outbreaks have occurred in cattle farms in south poland in malopolskie, podkarpackie, opolskie, and silesian provinces. the aim of this study was to characterize the q fever foci in poland. | 2013 | 24284912 |
the impact of q fever-phase-specific milk serology for the diagnosis of puerperal and chronic milk shedding of c. burnetii in dairy cows. | c. burnetii infection might be associated with puerperal shedding; additionally, the chronic shedding of this pathogen in milk has been observed in individual animals. a longitudinal survey was performed in an endemically infected dairy cow herd with 100 cows in order to compare phase-specific milk-serology with pathogen shedding. from march 2010 through december 2011, 870 individual milk samples from 212 cows were analysed using both quantitative (q) pcr and phase-specific antibody-elisa. the m ... | 2013 | 24199386 |
rapid, simple and sensitive detection of q fever by loop-mediated isothermal amplification of the htpab gene. | q fever is the most widespread zoonosis, and domestic animals are the most common sources of transmission. it is not only difficult to distinguish from other febrile diseases because of the lack of specific clinical manifestations in humans, but it is also difficult to identify the disease in c. burnetii-carrying animals because of the lack of identifiable features. conventional serodiagnosis requires sera from the acute and convalescent stages of infection, which are unavailable at early diagno ... | 2013 | 23696915 |
dairy goat demography and q fever infection dynamics. | between 2007 and 2009, the largest human q fever epidemic ever described occurred in the netherlands. the source was traced back to dairy goat farms, where abortion storms had been observed since 2005. since one putative cause of these abortion storms is the intensive husbandry systems in which the goats are kept, the objective of this study was to assess whether these could be explained by herd size, reproductive pattern and other demographic aspects of dutch dairy goat herds alone. we adapted ... | 2013 | 23621908 |
vectorborne diseases in west africa: geographic distribution and geospatial characteristics. | this paper provides an overview of the methods in which geographic information systems (gis) and remote sensing (rs) technology have been used to visualise and analyse data related to vectorborne diseases (vbd) in west africa and to discuss the potential for these approaches to be routinely included in future studies of vbds. gis/rs studies of diseases that are associated with a specific geographic landscape were reviewed, including malaria, human african trypanosomiasis, leishmaniasis, lymphati ... | 2013 | 23479360 |
polymicrobial endocarditis: chronic q fever and enterococcus faecalis coinfection. | 2013 | 23318110 | |
a model for the early identification of sources of airborne pathogens in an outdoor environment. | source identification in areas with outbreaks of airborne pathogens is often time-consuming and expensive. we developed a model to identify the most likely location of sources of airborne pathogens. | 2013 | 24324598 |
q fever outbreak in a goat herd--diagnostic investigations and measures for control. | this is a case report about a q fever infection of a goat herd with abortions and excretions of pathogens accompanied by human infection and disease. following a diagnosis of q fever in a goat herd, all animals were vaccinated with an inactivated phase 1 vaccine. the herd was kept isolated and animals were neither removed nor introduced so that monitoring of the course of the q fever infection of the individual dam was possible. over a period of two years following the diagnosis of a q fever inf ... | 2013 | 24199381 |
economic assessment of q fever in the netherlands. | in this paper the economic impact of controlling the q fever epidemic in 2007-2011 in the netherlands is assessed. whereas most of the long-term benefits of the implemented control programme stem from reduced disease burden and human health costs, the majority of short-term intervention costs were incurred in the dairy goat sector. the total intervention cost in agriculture amounted approximately 35,000 euro per daly occurred. by culling of infected animals, breeding prohibition and vaccination, ... | 2013 | 23866818 |
multiple strains of coxiella burnetii are present in the environment of st. paul island, alaska. | in 2010, coxiella burnetii was identified at a high prevalence in the placentas of northern fur seals (callorhinus ursinus) collected at a single rookery on st. paul island alaska; an area of the united states where the agent was not known to be present. as contamination was hypothesized as a potential cause of false positives, but nothing was known about environmental c. burnetii in the region, an environmental survey was conducted to look for the prevalence and distribution of the organism on ... | 2013 | 22747976 |
screening for coxiella burnetii seroprevalence in chronic q fever high-risk groups reveals the magnitude of the dutch q fever outbreak. | the netherlands experienced an unprecedented outbreak of q fever between 2007 and 2010. the jeroen bosch hospital (jbh) in 's-hertogenbosch is located in the centre of the epidemic area. based on q fever screening programmes, seroprevalence of igg phase ii antibodies to coxiella burnetii in the jbh catchment area was 10·7% [785 tested, 84 seropositive, 95% confidence interval (ci) 8·5-12·9]. seroprevalence appeared not to be influenced by age, gender or area of residence. extrapolating these dat ... | 2013 | 22691867 |
inactivation or clearance of coxiella burnetii in rat serum samples to enable safe serological testing. | to allow processing of serum samples from animals experimentally infected with coxiella burnetii outside the bsl-3 facility, an inactivation or clearance protocol that does not hamper serological testing may be required. the effects of filtration (0.1 µm pore size), heating at 56 °c for 30 min, addition of nan3 (0.09% w/v), and combinations thereof on the presence of viable c. burnetii as well as od-values in elisa were tested. only filtration was shown to effectively clear all culturable c. bur ... | 2013 | 22961372 |
lookback procedures after postdonation notifications during a q fever outbreak in the netherlands. | since 2007, large outbreaks of q fever occurred in the netherlands. the unprecedented number of q fever infections resulted in the need for the dutch blood transfusion service to evaluate the risk of transmission of coxiella burnetii via blood. | 2013 | 22803955 |
time-course of antibody responses against coxiella burnetii following acute q fever. | large outbreaks of q fever in the netherlands have provided a unique opportunity for studying longitudinal serum antibody responses in patients. results are presented of a cohort of 344 patients with acute symptoms of q fever with three or more serum samples per patient. in all these serum samples igm and igg against phase 1 and 2 coxiella burnetii were measured by an immunofluorescence assay. a mathematical model of the dynamic interaction of serum antibodies and pathogens was used in a mixed m ... | 2013 | 22475210 |
geographical distribution modelling for neospora caninum and coxiella burnetii infections in dairy cattle farms in northeastern spain. | maximum entropy ecological niche modelling and spatial scan statistic were utilized to predict the geographical range and to investigate clusters of infections for neospora caninum and coxiella burnetii in dairy cattle farms in catalonia, northeastern spain, using the maxent and satscan programs, respectively. the geographical distribution of neospora and coxiella with the highest level of probability (p > 0·60) covers central catalonia and spreads towards northeastern catalonia which contains a ... | 2013 | 22370223 |
[presence of q fever virus in bat eptesicus isabellinus (temminck) in morocco]. | 2013 | 13511085 | |
comparison of the performance of ifa, cfa, and elisa assays for the serodiagnosis of acute q fever by quality assessment. | the indirect immunofluorescence assay (ifa) is considered the reference method for diagnosing q fever, but serology is also performed by complement fixation assay (cfa) or enzyme-linked immunosorbent assay (elisa). however, comparability between these assays is not clear, and therefore a quality assessment was performed. a total of 25 serum samples from negative controls, q fever patients, and a serial diluted high-positive sample were analyzed in 10 dutch laboratories. six laboratories performe ... | 2013 | 23041450 |
could it be q fever? | 2013 | 23330744 | |
particulate matter strongly associated with human q fever in the netherlands: an ecological study. | there are still questions about the importance of different animal reservoirs and environmental factors that played a role in the large q fever epidemic in the netherlands. we therefore investigated the spatial association between reported q fever cases and different livestock and environmental factors at the national level. a spatial regression analysis was performed, with four-digit postal code areas as the unit of analysis. high level of particulate matter (< 24.5 μg/m³) with an aerodynamic d ... | 2013 | 23481147 |
a new assay: specific interferon-γ detection for the diagnosis of previous q fever. | 2013 | 23463639 | |
q fever and mediterranean spotted fever associated with hemophagocytic syndrome: case study and literature review. | hemophagocytosis during q fever (qf) and mediterranean spotted fever (msf) is rare and only a few cases have been reported. we aimed to investigate the characteristics, outcome, and treatment of qf/msf-associated hemophagocytosis. | 2013 | 23402798 |
acute q fever in northern queensland: variation in incidence related to rainfall and geographical location. | the aims of this study were to define the basic epidemiology of serologically confirmed acute q fever in patients tested via the townsville hospital laboratory from 2000 to 2010 and to determine the impact of geographical location and seasonality on the incidence of acute cases in the townsville region. seven statistical local areas (sla) were identified as having an incidence higher than the average queensland incidence over the study period. the sla with the highest incidence was woodstock-ros ... | 2013 | 22882795 |
bright spots: q fever prosthetic valve endocarditis. | 2013 | 24135510 | |
a dynamic case definition is warranted for adequate notification in an extended epidemic setting: the dutch q fever outbreak 2007-2009 as exemplar. | q fever is a notifiable disease in the netherlands:laboratories are obliged to notify possible cases to the municipal health services. these services then try to reconfirm cases with additional clinical and epidemiological data and provide anonymised reports to the national case register of notifiable diseases. since the start of the 2007–2009 dutch q fever outbreak,notification rules remained unchanged, despite new laboratory insights and altered epidemiology. in this study, we retrospectively ... | 2013 | 24135125 |
localizing chronic q fever: a challenging query. | chronic q fever usually presents as endocarditis or endovascular infection. we investigated whether 18f-fdg pet/ct and echocardiography were able to detect the localization of infection. also, the utility of the modified duke criteria was assessed. | 2013 | 24004470 |
assessing health status and quality of life of q-fever patients: the nijmegen clinical screening instrument versus the short form 36. | the aim of the study was to assess the use of the nijmegen clinical screening instrument (ncsi) and short form 36 (sf-36) in providing a detailed assessment of health status of q-fever patients and to evaluate which subdomains within the ncsi and sf-36 measure unique aspects of health status. | 2013 | 23826639 |
[the immune structure against q fever and tick-bite spotted fever group rickettsioses in the population and domestic animals of the republic of guinea]. | the circulation of the rickettsiae r.africae and c.brunetii, the causative agents of african tick-bite spotted fever and q fever, was first ascertained throughout the territory of the republic of guinea. the immune stratum against r.africae among the population varied 1.1 to 25.4% or 10.6+/-0.7% on average and that among the livestock did 0.6 to 18.8% or 7.6+/-0.6% on average. the proportion of sera to c,brunettii in the population was in the rage from 0.8 to 10.5% or 2.4+/-0.3% on average; that ... | 2013 | 23805485 |
evolution from acute q fever to endocarditis is associated with underlying valvulopathy and age and can be prevented by prolonged antibiotic treatment. | the prevention of q fever endocarditis through the use of systematic echocardiography and antibiotic prophylaxis in patients with acute q fever and valvulopathy has never been validated in a cohort study. | 2013 | 23794723 |
[milk goats and sheep are a definite source of q fever outbreak]. | 2013 | 23786118 | |
chronic q fever causing aortitis. | 2013 | 23684061 | |
culture negative prosthetic valve endocarditis in chronic q fever: an under-recognized entity. | 2013 | 23642595 | |
unexpected sequel of chronic q-fever endocarditis. | we report a patient with chronic q-fever endocarditis who was treated with bentall procedure on two occasions due to persistent endocarditis. a chronic pseudoaneurysm of the aortic root was discovered incidentally by cardiac magnetic resonance and computed tomography eight years post-operatively. due to chronicity of the pseudoaneurysm and great risk of re-intervention, conservative management was recommended. | 2013 | 23628330 |
large regional differences in serological follow-up of q fever patients in the netherlands. | during the dutch q fever epidemic more than 4,000 q fever cases were notified. this provided logistical challenges for the organisation of serological follow-up, which is considered mandatory for early detection of chronic infection. the aim of this study was to investigate the proportion of acute q fever patients that received serological follow-up, and to identify regional differences in follow-up rates and contributing factors, such as knowledge of medical practitioners. | 2013 | 23577152 |
q fever with transient antiphospholipid antibodies associated with cholecystitis and splenic infarction. | we describe a case of q fever associated with the transient presence of antiphospholipid antibodies in a 9-year-old boy presenting with acalculous cholecystitis and splenic infarction. antiphospholipid antibodies are commonly associated with acute q fever in adults but have previously been thought to be of little clinical significance. recent data suggest that antiphospholipid antibodies may be responsible for certain clinical manifestations of acute q fever. | 2013 | 23271442 |
[granulomatous hepatitis caused by q fever]. | we inform of one case of fever and characteristic hepatic granuloma in which the final diagnosis was q fever. the interest of this case lies in the fact that the patient did not have the usual epidemiological antecedent and its typical clinical presentation. | 2013 | 9504075 |
q-fever can simulate a lupus flare. | fever is a diagnostic challenge in the patient with lupus. infections can mimic a lupus flare which further complicates the diagnostic approach. moreover, immunosuppressive treatment of sle may promote the development of infections and poor outcome. we report the case of a patient with sle with an initial diagnosis of lupus flare, who was found to have q fever showing an excellent response to treatment with doxycycline. | 2012 | 22137637 |
hydroxychloroquine: from malaria to autoimmunity. | quinine was first recognized as a potent antimalarial agent hundreds of years ago. since then, the beneficial effects of quinine and its more advanced synthetic forms, chloroquine and hydroxychloroquine, have been increasingly recognized in a myriad of other diseases in addition to malaria. in recent years, antimalarials were shown to have various immunomodulatory effects, and currently have an established role in the management of rheumatic diseases, such as systemic lupus erythematosus and rhe ... | 2012 | 21221847 |
acute q fever myocarditis: thinking about a life-threatening but potentially curable condition. | 2012 | 22078989 | |
placental abruption remote from term associated with q fever infection. | it has been suggested that q fever infection in pregnancy is associated with various maternal and neonatal adverse outcomes, including intrauterine growth restriction, stillbirth, preterm delivery, intrauterine fetal death, and oligohydramnios. | 2012 | 22825280 |
successful treatment with azathioprine of relapsing rosai-dorfman disease of the central nervous system. | rosai-dorfman disease (rdd) is a rare non-langerhans histiocytosis that usually presents with lymphadenopathy. although isolated involvement of the cns was considered to be uncommon, numerous cases have been reported in recent years. for rdd of the cns, the treatment consists, in general, of surgery. in cases of partial resection or relapse, chemotherapy regimens, corticosteroids, and/or radiotherapy have yielded negative results. the authors describe the case of a 57-year-old man with a history ... | 2012 | 22725985 |
q fever and pneumonia in an area with a high livestock density: a large population-based study. | concerns about public health risks of intensive animal production in the netherlands continue to rise, in particular related to outbreaks of infectious diseases. the aim was to investigate associations between the presence of farm animals around the home address and q fever and pneumonia.electronic medical record data for the year 2009 of all patients of 27 general practitioners (gps) in a region with a high density of animal farms were used. density of farm animals around the home address was c ... | 2012 | 22685612 |
a case of acute q fever hepatitis diagnosed by f-18 fdg pet/ct. | a 53-year-old man with fever of unknown origin underwent f-18 fluorodeoxyglucose positron emission tomography/computed tomography (f-18 fdg pet/ct) as a workup for a fever of unknown origin. on presentation, he complained of fever, chills, and myalgia. the f-18 fdg pet/ct scan showed diffusely increased uptake of the liver with mild hepatomegaly. a liver biopsy then revealed fibrin-ring granulomas typically seen in q fever. the patient was later serologically diagnosed as having acute q fever as ... | 2012 | 24900046 |
q fever infection: inflammatory aortic root aneurysm in an hiv positive patient. | we describe a case of q fever infection with an inflammated proximal ascending aortic aneurysm in an hiv-infected patient. the patient was treated with aortic root replacement and medication for q fever, a combination of doxycycline and hydroxychloroquine in addition to highly active antiretroviral therapy. the combination of q fever and hiv infection has rarely been documented. a case of q fever infection of a proximal ascending aorta aneurysm in a patient with hiv co-infection has never been d ... | 2012 | 22641989 |
q fever endocarditis: does serology predict outcome? | q fever is an ubiquitous zoonosis caused by coxiella burneti, an intracellular bacterium that can produce acute or chronic infections in humans. these forms are characterized by different evolution, serological profile and treatment that must be very long to achieve a cure in chronic forms. however, the serological profile for diagnosis and the real value of serology for predicting outcome are controversial, and management dilemmas for many patients with q fever infection are continuously emergi ... | 2012 | 22639065 |
a program against bacterial bioterrorism: improved patient management and acquisition of new knowledge on infectious diseases. | in 2002 it was decided to establish laboratory facilities in denmark for diagnosing agents associated with bioterrorism in order to make an immediate appropriate response to the release of such agents possible. molecular assays for detection of specific agents and molecular and proteomic techniques for identification of bacteria were introduced as part of the program. all assays and techniques were made accessible for use in diagnosing patients, even when an intentional release was not suspected ... | 2012 | 22571372 |
chronic q fever: expert opinion versus literature analysis and consensus. | q fever has long been considered a rare disease. the extensive outbreak in the netherlands generated a body of literature based solely on the consensus in the netherlands. as a long-standing expert on q fever, i offer my experience and recommendations to the e-cdc and the dutch q fever consensus group. my (biased) opinion is that experts deeply involved in the field continue to be useful in the management of outbreaks and can avoid decisions that produce an unfavorable progression in patients. h ... | 2012 | 22537659 |
q fever outbreak in the village of noćaj, srem county, vojvodina province, serbia, january to february 2012. | from 27 january to 10 february 2012, a total of 43 cases of q fever were notified in the village of noćaj, srem county, autonomous province of vojvodina, republic of serbia. q fever was laboratory confirmed in 37 notified cases. alhough, the outbreak is considered over, the outbreak investigation is still ongoing in order to identify aetiologic factors relevant for this outbreak. | 2012 | 22516045 |
[today's threat of rickettsioses]. | rickettsioses are infectious diseases transmitted to human by arthropodes, characterized by different clinical manifestation, from subclinical symptoms, through the mild virus-like infection to severe disease with multiorgan complications. rickettsiosis include typhus, spotted fevers, anaplasmosis, bartonellosis and q fever. in some of these diseases respiratory symptoms predominate (i.e. acute q fever), where as one do not occure in the others at all. rickettsiosis treatment is based usually on ... | 2012 | 23394042 |
influence of the environment and occupational exposure on the occurrence of q fever. | q fever, which is caused by coxiella bumetii, is a worldwide zoonotic infectious disease and ruminants are the main reservoir for human infections. humans become infected primarily by inhaling aerosols that are contaminated with c. bumetii. ingestion (particularly drinking raw milk) and person-to-person transmission are minor routes. animals shed the bacterium in urine and faeces, and in very high concentrations in birth by-products. the bacterium persists in the environment in a resistant spore ... | 2012 | 23285522 |
q fever masquerading as prostate cancer metastases. | we report a case of q fever demonstrated on (99m)tc methylene diphosphonate bone scan and fluorodeoxyglucose (fdg) pet/ct. a 66-year-old man with newly diagnosed, low-grade prostate cancer presented with abdominal and bone pain. bone scan revealed multiple lesions suspicious for prostate cancer metastases. because of liver abnormalities on noncontrast ct, an fdg pet/ct was performed and demonstrated fdg-avid sclerotic bone lesions, infiltrative liver disease, and retroperitoneal adenopathy. this ... | 2012 | 22475908 |
why did patients with cardiovascular disease in the netherlands accept q fever vaccination? | this study examines patient's reasons for accepting q fever vaccination, including risk perception, feelings of doubt, social influence, information-seeking behavior, preventive measures taken, and perceptions regarding received information and governmental action. data was obtained from exit interviews conducted after q fever vaccination, between january and april 2011. a total of 413 patients with specific cardiovascular conditions in the netherlands participated in exit interviews; 70% were o ... | 2012 | 22475862 |
effectiveness and safety of minilaparoscopy-guided spleen biopsy: a retrospective series of 57 cases. | minilaparoscopy is an accepted method for liver biopsy. we report our experience with minilaparoscopy for splenic biopsy. | 2012 | 22350241 |
solitary igm phase ii response has a limited predictive value in the diagnosis of acute q fever. | we investigated the positive predictive value (ppv) of a solitary positive immunoglobulin m (igm) phase ii response for the serodiagnosis of acute q fever detected with either an indirect immunofluorescence assay (ifa) or an enzyme-linked immunosorbent assay (elisa). initial and follow-up sera from patients suspected of acute q fever were included if initially only igm phase ii tested positive with ifa in 2008 (n=92), or elisa in 2009 (n=85). a seroconversion for q fever was defined as an initia ... | 2012 | 22340504 |
[hemolytic anemia secondary to q fever]. | 2012 | 22316659 | |
self-reported sick leave and long-term health symptoms of q-fever patients. | in the netherlands, 1168 q-fever patients were notified in 2007 and 2008. patients and general practitioners (gps) regularly reported persisting symptoms after acute q-fever, especially fatigue and long periods of sick leave, to the public health authorities. international studies on smaller q-fever outbreaks demonstrate that symptoms may persist years after acute illness. data for the dutch outbreaks were unavailable. the aim of this study is to quantify sick leave after acute q-fever and long- ... | 2012 | 22315459 |
[persistent fatigue following q fever]. | in the netherlands, more than 4000 patient cases of acute q fever have been reported since 2007. approximately 20% of these patients subsequently developed long-term fatigue. such fatigue, as well as other physical symptoms and patient-perceived limitations in social functioning, have been compiled into what is known as the q fever fatigue syndrome (qfs). the number of dutch patients having qfs is expected to increase over the next years. the chance of a spontaneous recovery during the first six ... | 2012 | 23191971 |
secondary hemophagocytic lymphohistiocytosis in zoonoses. a systematic review. | hemophagocytic lymphohistiocytosis (hlh) is a rare syndrome that is often fatal despite treatment. it is caused by a dysregulation in natural killer t-cell function, resulting in activation and proliferation of histiocytes with uncontrolled hemophagocytosis and cytokines overproduction. the syndrome is characterized by fever, hepatosplenomegaly, cytopenias, liver dysfunction, and hyperferritinemia. hlh can be either primary, with a genetic aetiology, or secondary, associated with malignancies, a ... | 2012 | 23104648 |
[the content of rosette-forming neutrophils and lysozyme in patients with q-fever]. | the article deals with the results of study of 35 patients with q-fever and 30 donors to determine the content of rosette-forming neutrophils, lysozyme activity of blood and saliva. on the second week of disease it was revealed the activation of compensative immune mechanisms and on third and fourth week inhibition of these mechanisms. | 2012 | 23097995 |
[risk factors and preventive measures regarding q fever transmission in the sheep abattoir]. | 2012 | 22900422 | |
defining chronic q fever: a matter of debate. | 2012 | 22898388 | |
applicability of evidence-based practice in public health: risk assessment on q fever under an ongoing outbreak. | with reference to the q fever outbreak in the netherlands in 2009-10, we tested if an evidence-based approach, comparable to the methodology used in clinical medicine, was appropriate for giving public health advice under time constrains. according to the principles of evidence-based methodologies, articles were retrieved from bibliographic databases and categorised by type and size, outcome, strengths and limitations. the risk assessment was conducted in two months and involved six staff member ... | 2012 | 22297099 |
q fever: new insights, still many queries. | 2012 | 22297098 | |
chronic q fever: review of the literature and a proposal of new diagnostic criteria. | a review was performed to determine clinical aspects and diagnostic tools for chronic q fever. we present a dutch guideline based on literature and clinical experience with chronic q fever patients in the netherlands so far. in this guideline diagnosis is categorized as proven, possible or probable chronic infection based on serology, pcr, clinical symptoms, risk factors and diagnostic imaging. | 2012 | 22226692 |
smooth incidence maps give valuable insight into q fever outbreaks in the netherlands. | from 2007 through 2009, the netherlands faced large outbreaks of human q fever. control measures focused primarily on dairy goat farms because these were implicated as the main source of infection for the surrounding population. however, in other countries, outbreaks have mainly been associated with non-dairy sheep and the netherlands has many more sheep than goats. therefore, a public discussion arose about the possible role of non-dairy (meat) sheep in the outbreaks. to inform decision makers ... | 2012 | 23242690 |
epidemic q fever in humans in the netherlands. | in 2005, q fever was diagnosed on two dairy goat farms and 2 years later it emerged in the human population in the south of the netherlands. from 2007 to 2010, more than 4,000 human cases were notified with an annual seasonal peak. the outbreaks in humans were mainly restricted to the south of the country in an area with intensive dairy goat farming. in the most affected areas, up to 15% of the population may have been infected. the epidemic resulted in a serious burden of disease, with a hospit ... | 2012 | 22711640 |
seroprevalence of major bovine-associated zoonotic infectious diseases in the lao people's democratic republic. | bovine-associated zoonotic infectious diseases pose a significant threat to human health in the lao people's democratic republic (lao pdr). in all, 905 cattle and buffalo serum samples collected in northern lao pdr in 2006 were used to determine seroprevalence of five major bovine zoonotic infectious diseases that included taenia saginata cysticercosis, bovine tuberculosis, q-fever, bovine brucellosis, and bovine leptospirosis. five enzyme-linked immunosorbent assays (elisas) were used to test f ... | 2012 | 22651388 |
reported vectorborne and zoonotic diseases, u.s. air force, 2000-2011. | during 2000-2011, u.s. air force public health officers reported 770 cases of vectorborne and zoonotic diseases diagnosed at air force medical treatment facilities. cases of lyme disease accounted for 70 percent (n=538) of all cases and most cases of lyme disease (57%) were reported from bases in the northeastern u.s. and in germany. the annual numbers of reported lyme disease cases were much higher during the last four years than earlier in the surveillance period. the next most commonly report ... | 2012 | 23121007 |
letter to the editor: screening for coxiella burnetii infection during pregnancy: pros and cons according to the wilson and jungner criteria. | 2012 | 22370018 | |
risk factors of coxiella burnetii (q fever) seropositivity in veterinary medicine students. | q fever is an occupational risk for veterinarians, however little is known about the risk for veterinary medicine students. this study aimed to assess the seroprevalence of coxiella burnetii among veterinary medicine students and to identify associated risk factors. | 2012 | 22363803 |
presence of antibodies against coxiella burnetii and risk of spontaneous abortion: a nested case-control study. | q fever is a bacterial zoonosis caused by infection with coxiella burnetii. it is well established that q fever causes fetal loss in small ruminants. the suspicion has been raised that pregnant women may also experience adverse pregnancy outcome when the infection is acquired or reactivated during pregnancy. the purpose of this study was to assess the potential association between serologic markers of infection with c. burnetii and spontaneous abortion. | 2012 | 22363769 |
comparison of q fever serology methods in cattle, goats, and sheep. | coxiella burnetii is an obligate intracellular bacterium that is responsible for the zoonotic disease q fever. the distribution of this agent is worldwide except for new zealand, and infection can be asymptomatic in both human beings and animals. chronic exposures can produce abortions, stillbirths, and infertility issues in animals and endocarditis in human beings. a commercial enzyme-linked immunosorbent assay (elisa) kit marketed in the european union was purchased to compare c. burnetii anti ... | 2012 | 22362532 |
defective monocyte dynamics in q fever granuloma deficiency. | the outcome of q fever, an infectious disease caused by coxiella burnetii, is associated with granuloma formation. granulomas are present in patients with resolutive q fever but are lacking in patients with chronic q fever. | 2012 | 22351939 |
coxiella burnetii in bulk tank milk samples from dairy goat and dairy sheep farms in the netherlands in 2008. | in 2007, a human q fever epidemic started, mainly in the south eastern part of the netherlands with a suspected indirect relation to dairy goats, and, to a lesser degree, to dairy sheep. this article describes the q fever prevalences in dutch dairy goat and dairy sheep bulk tank milk (btm) samples, using a real-time (rt) pcr and elisa. results of btm pcr and elisa were compared with the serological status of individual animals, and correlations with a history of q fever abortion were determined. ... | 2012 | 22351793 |
coxiella burnetii infection of a bovine jugular vein conduit in a child. | we report a case of an 11-year-old girl with coxiella burnetii infection of a bovine jugular vein conduit which is an extremely rare manifestation of q fever. the role of surgery in the management of c. burnetii endovascular infection and the use of serology are discussed. | 2012 | 22349674 |
screening-level risk assessment of coxiella burnetii (q fever) transmission via aeration of drinking water. | a screening-level risk assessment of q fever transmission through drinking water produced from groundwater in the vicinity of infected goat barnyards that employed aeration of the water was performed. quantitative data from scientific literature were collected and a quantitative microbial risk assessment approach was followed. an exposure model was developed to calculate the dose to which consumers of aerated groundwater are exposed through aerosols inhalation during showering. the exposure asse ... | 2012 | 22309101 |
screening for coxiella burnetii infection during pregnancy: pros and cons according to the wilson and jungner criteria. | in europe the incidence of human q fever has dramatically increased over the previous years. untreated infections with coxiella burnetii, the causal agent of q fever, have been associated with both obstetric and maternal complications. the majority of pregnant women with a c. burnetii infection remain asymptomatic, hence screening could be of value to prevent unwanted outcomes in this high-risk group. we applied the updated wilson and jungner criteria to review the evidence for routine screening ... | 2012 | 22297102 |
shifting priorities in the aftermath of a q fever epidemic in 2007 to 2009 in the netherlands: from acute to chronic infection. | from 2007 to 2009, the netherlands faced large seasonal outbreaks of q fever, in which infected dairy goat farms were identified as the primary sources. veterinary measures including vaccination of goats and sheep and culling of pregnant animals on infected farms seem to have brought the q fever problem under control. however, the epidemic is expected to result in more cases of chronic q fever among risk groups in the coming years. in the most affected area, in the south of the country, more tha ... | 2012 | 22297101 |
relation between q fever notifications and coxiella burnetii infections during the 2009 outbreak in the netherlands. | large outbreaks of q fever in the netherlands from 2007 to 2009 were monitored using notification data of acute clinical q fever. however, the notification system provides no information on infections that remain subclinical or for which no medical attention is sought. the present study was carried out immediately after the peak of the 2009 outbreak to estimate the ratio between coxiella burnetii infections and q fever notifications. in 23 postcode areas in the high-incidence area, notification ... | 2012 | 22297100 |
q fever across the dutch border in limburg province, belgium. | data from three different data sources were compiled to estimate the presence of coxiella burnetii in the belgian limburg province for both humans and livestock. first, serological data of all samples sent to the belgian reference centre (2003–2010) for human q fever were analysed, showing evidence for an acute q fever infection in 1–5% of the cases. second, a multi-centre prospective survey was conducted in limburg in 2010 to detect undiagnosed human cases; evidence for a recent infection with ... | 2012 | 22290347 |
q fever osteomyelitis: a case report and literature review. | q fever is a worldwide zoonosis caused by coxiella burnetii. the clinical manifestations of q fever include endocarditis, pneumonitis and hepatitis. disease awareness and evolving diagnostic tests have enabled the recognition of unusual manifestations of q fever. we report a case of q fever osteomyelitis. a 51-year-old patient was admitted to hospital because of fever, leg weakness, and asthenia. his past medical history included surgery and a bone graft for the treatment of a giant cell tumor o ... | 2012 | 22285690 |
coxiella burnetii infection of marine mammals in the pacific northwest, 1997-2010. | q fever is a zoonotic disease caused by the bacterium coxiella burnetii. humans are commonly exposed via inhalation of aerosolized bacteria derived from the waste products of domesticated sheep and goats, and particularly from products generated during parturition. however, many other species can be infected with c. burnetii, and the host range and full zoonotic potential of c. burnetii is unknown. two cases of c. burnetii infection in marine mammal placenta have been reported, but it is not kno ... | 2012 | 22247392 |
detection of coxiella burnetii dna on small-ruminant farms during a q fever outbreak in the netherlands. | during large q fever outbreaks in the netherlands between 2007 and 2010, dairy goat farms were implicated as the primary source of human q fever. the transmission of coxiella burnetii to humans is thought to occur primarily via aerosols, although available data on c. burnetii in aerosols and other environmental matrices are limited. during the outbreak of 2009, 19 dairy goat farms and one dairy sheep farm were selected nationwide to investigate the presence of c. burnetii dna in vaginal swabs, m ... | 2012 | 22247143 |
prevalence of coxiella burnetii antibodies among febrile patients in croatia, 2008-2010. | despite the widespread distribution of q fever, the prevalence in humans is not accurately known, because many infected people seroconvert without symptoms or with a mild febrile disease. the aim of this study was to determine the seroprevalence of q fever in different regions of croatia. during a 2-year period (2008-2010), serum samples from 552 febrile patients with prolonged cough aged 1-88 were tested for the presence of coxiella burnetii antibodies by using indirect immunofluorescent assay. ... | 2012 | 22239180 |
q fever: baseline monitoring of a sheep and a goat flock associated with human infections. | animal losses due to abortion and weak offspring during a lambing period amounted up to 25% in a goat flock and up to 18% in a sheep flock kept at an experimental station on the swabian alb, germany. fifteen out of 23 employees and residents on the farm tested positive for coxiella burnetii antibodies by enzyme-linked immunosorbent assay (elisa) and indirect immunofluorescence assay. ninety-four per cent of the goats and 47% of the sheep were seropositive for c. burnetii by elisa. blood samples ... | 2012 | 22217267 |
zoonotic infections in native communities of james bay, canada. | the cree communities of james bay might be at risk of contracting zoonoses from their contacts with wildlife. evidence of exposure to seven zoonotic infections, namely trichinella spp., toxoplasma gondii, toxocara canis, echinococcus granulosus, leptospira spp., coxiella burnetii, and francisella tularensis, was sought in sera from 267 residents of chisasibi (166) and waskaganish (101). study participants responded to questionnaires documenting socio-demographic characteristics and hunting and t ... | 2012 | 22217180 |
the first reported cases of q fever endocarditis in thailand. | we describe the first two reported cases of q fever endocarditis in thailand. both patients were male, had pre-existing heart valve damage and had contact with cattle. heightened awareness of q fever could improve diagnosis and case management and stimulate efforts to identify risk factors and preventive measures. | 2012 | 24470937 |
[leptospira spp. and coxiella burnetii infections occuring in radomskie district in people of selected professional groups]. | leptospirosis and q fever are a zoonotic diseases with global occurring. | 2012 | 23484388 |
dynamics of coxiella burnetii antibodies and seroconversion in a dairy cow herd with endemic infection and excreting high numbers of the bacterium in the bulk tank milk. | possible factors related to seropositivity and seroconversion to coxiella burnetii were examined in a dairy herd with a high coxiella-seroprevalence and high excretion levels of the bacterium in the bulk tank milk. antibodies were detected by using a commercial elisa test in 50.7% of 603 parous cows. the likelihood of c. burnetii seropositivity significantly increased by factors of 1.87 and 1.61 for cows in their first and second terms of pregnancy, respectively, compared to non-pregnant cows. i ... | 2012 | 22475008 |