Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| the central role of mosquito cytochrome p450 cyp6zs in insecticide detoxification revealed by functional expression and structural modelling. | the resistance of mosquitoes to chemical insecticides is threatening vector control programmes worldwide. cytochrome p450 monooxygenases (cyps) are known to play a major role in insecticide resistance, allowing resistant insects to metabolize insecticides at a higher rate. among them, members of the mosquito cyp6z subfamily, like aedes aegypti cyp6z8 and its anopheles gambiae orthologue cyp6z2, have been frequently associated with pyrethroid resistance. however, their role in the pyrethroid degr ... | 0 | 23844938 |
| multimodal integration of carbon dioxide and other sensory cues drives mosquito attraction to humans. | multiple sensory cues emanating from humans are thought to guide blood-feeding female mosquitoes to a host. to determine the relative contribution of carbon dioxide (co2) detection to mosquito host-seeking behavior, we mutated the aaeggr3 gene, a subunit of the heteromeric co2 receptor in aedes aegypti mosquitoes. gr3 mutants lack electrophysiological and behavioral responses to co2. these mutants also fail to show co2-evoked responses to heat and lactic acid, a human-derived attractant, suggest ... | 0 | 24581501 |
| nutrition-dependent control of insect development by insulin-like peptides. | in metazoans, members of the insulin-like peptide (ilp) family play a role in multiple physiological functions in response to the nutritional status. ilps have been identified and characterized in a wide variety of insect species. insect ilps that are mainly produced by several pairs of medial neurosecretory cells in the brain circulate in the hemolymph and act systemically on target tissues. physiological and biochemical studies in lepidoptera and genetic studies in the fruit fly have greatly e ... | 0 | 26664828 |
| cloning, expression analysis, and molecular modeling of the gamma-aminobutyric acid receptor alpha2 subunit gene from the common cutworm, spodoptera litura. | intensive research on the molecule structures of the gamma-nminobutyric acid (gaba) receptor in agricultural pests has great significance to the mechanism investigation, resistance prevention, and molecular design of novel pesticides. the gaba receptor a2 (slgabarĪ±2) subunit gene in spodoptera litura (fabricius) (lepidoptera: noctuidae) was cloned using the technologies of reverse transcription pcr and rapid amplification of cdna ends. the gemonic dna sequence of slgabarĪ±2 has 5164 bp with 8 exo ... | 0 | 23909412 |
| towards abolition of immunogenic structures in insect cells: characterization of a honey-bee (apis mellifera) multi-gene family reveals both an allergy-related core alpha1,3-fucosyltransferase and the first insect lewis-histo-blood-group-related antigen-synthesizing enzyme. | glycoproteins from honey-bee (apis mellifera), such as phospholipase a2 and hyaluronidase, are well-known major bee-venom allergens. they carry n-linked oligosaccharide structures with two types of alpha1,3-fucosylation: the modification by alpha1,3-fucose of the innermost core glcnac, which constitutes an epitope recognized by ige from some bee-venom-allergic patients, and an antennal lewis-like galnacbeta1,4(fucalpha1,3)glcnac moiety. we now report the cloning and expression of two cdnas encod ... | 0 | 17029591 |
| comparative genomics of odorant binding proteins in anopheles gambiae, aedes aegypti, and culex quinquefasciatus. | about 1 million people in the world die each year from diseases spread by mosquitoes, and understanding the mechanism of host identification by the mosquitoes through olfaction is at stake. the role of odorant binding proteins (obps) in the primary molecular events of olfaction in mosquitoes is becoming an important focus of biological research in this area. here, we present a comprehensive comparative genomics study of obps in the three disease-transmitting mosquito species anopheles gambiae, a ... | 0 | 23292137 |
| molecular determinants of differential ligand sensitivities of insect ecdysteroid receptors. | the functional receptor for insect ecdysteroid hormones is a heterodimer consisting of two nuclear hormone receptors, ecdysteroid receptor (ecr) and the retinoid x receptor homologue ultraspiracle (usp). although ecdysone is commonly thought to be a hormone precursor and 20-hydroxyecdysone (20e), the physiologically active steroid, little is known about the relative activity of ecdysteroids in various arthropods. as a step toward characterization of potential differential ligand recognition, we ... | 0 | 10805730 |
| but2 is a member of the third major group of hat transposons and is involved in horizontal transfer events in the genus drosophila. | the hat superfamily comprises a large and diverse array of dna transposons found in all supergroups of eukaryotes. here we characterized the drosophila buzzatii but2 element and found that it harbors a five-exon gene encoding a 643-aa putatively functional transposase. a phylogeny built with 85 hat transposases yielded, in addition to the two major groups already described, ac and buster, a third one comprising 20 sequences that includes but2, tip100, hat-4_bm, and rp-hat1. this third group is h ... | 0 | 24459285 |
| cloning and immunoreactivity of the 5-ht 1mac and 5-ht 2mac receptors in the central nervous system of the freshwater prawn macrobrachium rosenbergii. | biogenic amines are implicated in several mental disorders, many of which involve social interactions. simple model systems, such as crustaceans, are often more amenable than vertebrates for studying mechanisms underlying behaviors. although various cellular responses of biogenic amines have been characterized in crustaceans, the mechanisms linking these molecules to behavior remain largely unknown. observed effects of serotonin receptor agonists and antagonists in abdomen posture, escape respon ... | 0 | 19184976 |
| proteome changes in the plasma of papilio xuthus (lepidoptera: papilionidae): effect of parasitization by the endoparasitic wasp pteromalus puparum (hymenoptera: pteromalidae). | although the biochemical dissection of parasitoid-host interactions is becoming well characterized, the molecular knowledge concerning them is minimal. in order to understand the molecular bases of the host immune response to parasitoid attack, we explored the response of papilio xuthus parasitized by the endoparasitic wasp pteromalus puparum using proteomic approach. by examining the differential expression of plasma proteins in the parasitized and unparasitized host pupae by two-dimensional (2 ... | 0 | 19489110 |
| foreword. | 0 | 24473796 | |
| cloning and sequence analysis of chitin synthase gene fragments of demodex mites. | to our knowledge, few reports on demodex studied at the molecular level are available at present. in this study our group, for the first time, cloned, sequenced and analyzed the chitin synthase (chs) gene fragments of demodex folliculorum, demodex brevis, and demodex canis (three isolates from each species) from xi'an china, by designing specific primers based on the only partial sequence of the chs gene of d. canis from japan, retrieved from genbank. results show that amplification was successf ... | 0 | 23024043 |
| insights into the venom composition of the ectoparasitoid wasp nasonia vitripennis from bioinformatic and proteomic studies. | with the nasonia vitripennis genome sequences available, we attempted to determine the proteins present in venom by two different approaches. first, we searched for the transcripts of venom proteins by a bioinformatic approach using amino acid sequences of known hymenopteran venom proteins. second, we performed proteomic analyses of crude n. vitripennis venom removed from the venom reservoir, implementing both an off-line two-dimensional liquid chromatography matrix-assisted laser desorption/ io ... | 0 | 20167014 |
| mechanisms and dynamics of orphan gene emergence in insect genomes. | orphan genes are defined as genes that lack detectable similarity to genes in other species and therefore no clear signals of common descent (i.e., homology) can be inferred. orphans are an enigmatic portion of the genome because their origin and function are mostly unknown and they typically make up 10% to 30% of all genes in a genome. several case studies demonstrated that orphans can contribute to lineage-specific adaptation. here, we study orphan genes by comparing 30 arthropod genomes, focu ... | 0 | 23348040 |
| a visible dominant marker for insect transgenesis. | transgenesis of most insects currently relies on fluorescence markers. here we establish a transformation marker system causing phenotypes visible to the naked eye due to changes in the color of melanin pigments, which are widespread in animals. ubiquitous overexpression of arylalkylamine-n-acetyl transferase in the silkworm, bombyx mori, changes the color of newly hatched first-instar larvae from black to a distinctive light brown color, and can be used as a molecular marker by directly connect ... | 0 | 23250425 |
| a mosquito sperm's journey from male ejaculate to egg: mechanisms, molecules, and methods for exploration. | the fate of mosquito sperm in the female reproductive tract has been addressed sporadically and incompletely, resulting in significant gaps in our understanding of sperm-female interactions that ultimately lead to fertilization. as with other diptera, mosquito sperm have a complex journey to their ultimate destination, the egg. after copulation, sperm spend a short time at the site of insemination where they are hyperactivated and quickly congregate near the entrance of the spermathecal ducts. w ... | 0 | 27147424 |
| inner workings: a big role for a microbial parasite. | 0 | 27095842 | |
| sub-lethal metal stress response of larvae of aedes aegypti. | aedes aegypti (diptera: culicidae) has adapted to urban environments; the urbanisation process provides suitable habitats for this disease vector subsequently increasing the probability of the transmission of pathogens in high-density environments. urban environments provide metal stressed larval habitats. however, little is known about the physiological cost of metal stress or how this might affect the performance of this mosquito species. this study aims to characterise the sub-lethal physiolo ... | 0 | 24926118 |
| contribution of dengue fever to the burden of acute febrile illnesses in papua new guinea: an age-specific prospective study. | malaria is a major contributor to the burden of febrile illnesses in papua new guinea (png). dengue fever (df) is likely to contribute; however, its epidemiology in png is poorly understood. we performed a prospective age-stratified study in outpatient clinics investigating the prevalence of df; 578 patients were enrolled, and 317 patients with a negative rapid diagnostic test (rdt) for malaria were tested for dengue. malaria was confirmed in 52% (301/578, 95% confidence interval [ci] = 48-56%), ... | 0 | 21734138 |
| mosquitocidal properties of igg targeting the glutamate-gated chloride channel in three mosquito disease vectors (diptera: culicidae). | the glutamate-gated chloride channel (glucl) is a highly sensitive insecticide target of the avermectin class of insecticides. as an alternative to using chemical insecticides to kill mosquitoes, we tested the effects of purified immunoglobulin g (igg) targeting the extracellular domain of glucl from anopheles gambiae (agglucl) on the survivorship of three key mosquito disease vectors: anopheles gambiae s.s., aedes aegypti and culex tarsalis. when administered through a single blood meal, anti-a ... | 0 | 25994632 |
| diversity of wolbachia pipientis strain wpip in a genetically admixtured, above-ground culex pipiens (diptera: culicidae) population: association with form molestus ancestry and host selection patterns. | analysis of molecular genetic diversity in nine marker regions of five genes within the bacteriophage wo genomic region revealed high diversity of the wolbachia pipentis strain wpip in a population of culex pipiens l. sampled in metropolitan chicago, il. from 166 blood fed females, 50 distinct genetic profiles of wpip were identified. rarefaction analysis suggested a maximum of 110 profiles out of a possible 512 predicted by combinations of the nine markers. a rank-abundance curve showed that fe ... | 0 | 22679853 |
| effects of temperature on emergence and seasonality of west nile virus in california. | temperature has played a critical role in the spatiotemporal dynamics of west nile virus transmission throughout california from its introduction in 2003 through establishment by 2009. we compared two novel mechanistic measures of transmission risk, the temperature-dependent ratio of virus extrinsic incubation period to the mosquito gonotrophic period (bt), and the fundamental reproductive ratio (r(0)) based on a mathematical model, to analyze spatiotemporal patterns of receptivity to viral ampl ... | 0 | 22556092 |
| evaluation of carbon dioxide- and 1-octen-3-ol-baited centers for disease control fay-prince traps to collect aedes albopictus. | during the summer of 2001, field studies were performed to evaluate the effects of carbon dioxide (co2) and 1-octen-3-ol (octenol) on the ability to collect aedes albopictus with centers for disease control (cdc) fay-prince traps. results from these studies indicated that ae. albopictus is significantly more attracted to co2- or co2 + octenol-baited cdc fay-prince traps than unbaited or octenol-baited traps. however, the difference between the responses to co2 and co2 + octenol was not statistic ... | 0 | 14710753 |
| epidemic infections and their relevance to the gulf and other arabian peninsula countries. | 0 | 24019727 | |
| preliminary analysis of several attractants and spatial repellents for the mosquito, aedes albopictus using an olfactometer. | mosquito attractants and spatial repellents hold great promise in controlling mosquito pests. in assessing the effectiveness of mosquito attractants and repellents, a good olfactometer system, and optimized testing conditions, are essential. in this research, we demonstrated the usefulness of an olfactometer system, and optimized testing conditions for aedes albopictus (diptera: culicidae). we found no significant difference in the biting activity of the insect between 8:00 and 22:00. furthermor ... | 0 | 23418948 |
| culex mosquitoes are experimentally unable to transmit zika virus. | we report that two laboratory colonies of culex quinquefasciatus and culex pipiens mosquitoes were experimentally unable to transmit zikv either up to 21 days post an infectious blood meal or up to 14 days post intrathoracic inoculation. infectious viral particles were detected in bodies, heads or saliva by a plaque forming unit assay on vero cells. we therefore consider it unlikely that culex mosquitoes are involved in the rapid spread of zikv. | 0 | 27605159 |
| experimental investigation of the susceptibility of italian culex pipiens mosquitoes to zika virus infection. | we investigated the susceptibility of an italian population of culex pipiens mosquitoes to zika virus (zikv) infection, tested in parallel with aedes aegypti, as a positive control. we analysed mosquitoes at 0, 3, 7, 10, 14, 20 and 24 days after an infectious blood meal. viral rna was detected in the body of cx. pipiens up to three days post-infection, but not at later time points. our results indicate that cx. pipiens is not susceptible to zikv infection. | 0 | 27605056 |
| zika in the united states: how are we preparing? | 0 | 27581255 | |
| the mysterious zika virus: adding to the tropical flavivirus mayhem. | until now, known as the demure cousin of dengue virus (denv) inhabiting africa, zika virus (zikv) has reinvented itself to cause explosive epidemics captivating the western hemisphere. the outbreak causing potential for zikv was realized when it made its way from africa to yap island micronesia in 2007, and in french polynesia in 2013. from there, it moved on to brazil in 2015. now zikv has infected people in more than 33 countries in central and south america and the caribbean. moreover the epi ... | 0 | 27763483 |
| vector-borne disease, cities, and climate change. | 0 | 27737979 | |
| a search for mosquito larvicidal compounds by blocking the sterol carrying protein, aescp-2, through computational screening and docking strategies. | sterol is a very vital compound for most of the insects and mosquitoes to complete their life cycle. unfortunately mosquitoes cannot synthesize the sterol, it depends on mammals for the same. mosquitoes take the sterol from the plant decays during their larval stage in the form of phytosterol, which is then converted to cholesterol for further growth and reproduction. this conversion occurs with the help of the sterol carrier protein 2(scp2). | 0 | 21808576 |
| mayaro virus and dengue virus 1 and 4 natural infection in culicids from cuiabá, state of mato grosso, brazil. | this study aimed to verify the diversity of culicidae species and their frequency of infection with flaviviruses and alphaviruses in cuiabá, state of mato grosso, brazil. mosquitoes were captured with nasci aspirators and hand net in 200 census tracts, identified alive at species level and pooled in one-20 (11,090 mosquitoes, 14 species). female pools (n = 610) were subjected to multiplex seminested-reverse transcription-polymerase chain reaction (rt-pcr) for 11 flavivirus and five alphavirus. p ... | 0 | 26784852 |
| is transfusion-transmitted dengue fever a potential public health threat? | dengue is an arboviruses due to single-stranded enveloped ribonucleic acid viruses, named dengue viruses (denv), that include four serotypes and are mainly transmitted via the bite of mosquitoes of the genus aedes (a. aegypti and a. albopictus). the distribution of the disease was historically limited to intertropical areas; however, during the last thirty years, the perimeter of the disease extended considerably and temperate areas are now at risk of outbreaks. the present global burden of deng ... | 0 | 25964876 |
| advances and controversies in yellow fever vaccination. | ever since its development in 1937, the live-attenuated 17d yellow fever (yf) vaccine has been one of the most effective vaccines available to man. in this review we highlight the major steps in the development of 17d yf vaccine. we discuss the use of neutralizing antibodies as a surrogate marker for protection, and explore the strengths and weaknesses of the current plaque reduction neutralization test (prnt), a technique developed in the 1960s that continues to be superior to every modern test ... | 0 | 24757521 |
| indigenous dengue fever, buenos aires, argentina. | 0 | 18760035 | |
| thoughts around the zika virus crisis. | as a lot of reviews are available on zika virus (zikv), in this short commentary, we will focus on the recent advances and gaps in knowledge regarding our understanding of zikv infections and on the reaction to the "zikv crisis." | 0 | 27832453 |
| geographic variation in adult survival and reproductive tactics of the mosquito aedes albopictus. | climate differences across latitude can result in seasonal constraints and selection on life history characters. since aedes albopictus (skuse) invaded north america in the mid-1980s, it has spread across a range of approximately 14 degrees latitude and populations in the north experience complete adult mortality due to cold winter temperatures that are absent in the south. life table experiments were conducted to test for differences in the adult survival and reproductive schedules of ae. albop ... | 0 | 18402136 |
| emerging viral diseases. | 0 | 18491811 | |
| in search of a better mosquito repellent. | 0 | 18709154 | |
| survival of west nile virus-challenged southern house mosquitoes, culex pipiens quinquefasciatus, in relation to environmental temperatures. | we investigated the effect of west nile virus (wnv) infection on survival in two colonies of culex pipiens quinquefasciatus say (diptera: culicidae) originating from vero beach and gainesville, fl. mosquitoes were fed west nile virus-infected blood and checked daily for survival. exposure to wnv decreased survival among cx. p. quinquefasciatus from gainesville relative to unexposed individuals at 31° c. in contrast, exposure to wnv enhanced survival among cx. p. quinquefasciatus from vero beach ... | 0 | 24820564 |
| zika virus, french polynesia, south pacific, 2013. | 0 | 24856001 | |
| public health response to aedes aegypti and ae. albopictus mosquitoes invading california, usa. | aedes aegypti and ae. albopictus mosquitoes, primary vectors of dengue and chikungunya viruses, were recently detected in california, usa. the threat of potential local transmission of these viruses increases as more infected travelers arrive from affected areas. public health response has included enhanced human and mosquito surveillance, education, and intensive mosquito control. | 0 | 26401891 |
| regulation of physiological processes by micrornas in insects. | micrornas (mirnas) are small non-coding rnas that function in gene regulatory processes in plants and animals by targeting sites within messenger rna. in insects, mirnas have been shown to regulate a variety of physiological processes throughout insect development, including molting, metamorphosis, oogenesis, embryogenesis, behavior and host-pathogen interactions. the roles of mirnas in the model organism, drosophila melanogaster, have been studied extensively due to the conserved nature of mirn ... | 0 | 26251827 |
| hla class ii allele polymorphism in an outbreak of chikungunya fever in middle andaman, india. | a sudden upsurge of fever cases with joint pain was observed in the outpatient department, community health centre, rangat during july-august 2010 in rangat middle andaman, india. the aetiological agent responsible for the outbreak was identified as chikungunya virus (chikv), by using rt-pcr and igm elisa. the study investigated the association of polymorphisms in the human leucocyte antigen class ii genes with susceptibility or protection against chikv. one hundred and one patients with clinica ... | 0 | 23710940 |
| next-generation sequencing in clinical virology: discovery of new viruses. | viruses are a cause of significant health problem worldwide, especially in the developing nations. due to different anthropological activities, human populations are exposed to different viral pathogens, many of which emerge as outbreaks. in such situations, discovery of novel viruses is utmost important for deciding prevention and treatment strategies. since last century, a number of different virus discovery methods, based on cell culture inoculation, sequence-independent pcr have been used fo ... | 0 | 26279987 |
| analysis of post-blood meal flight distances in mosquitoes utilizing zoo animal blood meals. | we assessed the post-blood meal flight distance of four mosquito species in a unique environment using blood meal analysis. mosquitoes were trapped at the rio grande zoo in albuquerque, nm, and the blood source of blood-engorged mosquitoes was identified. the distance from the enclosure of the animal serving as a blood source to the trap site was then determined. we found that mosquitoes captured at the zoo flew no more than 170 m with an average distance of 106.7 m after taking a blood meal. th ... | 0 | 22548540 |
| aedes (stegomyia) aegypti and aedes (howardina) cozumelensis in yucatán state, méxico, with a summary of published collection records for ae. cozumelensis. | we collected mosquito immatures from artificial containers during 2010-2011 from 26 communities, ranging in size from small rural communities to large urban centers, located in different parts of yucatán state in southeastern méxico. the arbovirus vector aedes (stegomyia) aegypti was collected from all 26 examined communities, and nine of the communities also yielded another container-inhabiting aedes mosquito: aedes (howardina) cozumelensis. the communities from which ae. cozumelensis were coll ... | 0 | 23181861 |
| urbanization and geographic expansion of zoonotic arboviral diseases: mechanisms and potential strategies for prevention. | arthropod-borne viruses (arboviruses) mainly infect people via direct spillover from enzootic cycles. however, dengue, chikungunya, and yellow fever viruses have repeatedly initiated urban transmission cycles involving human amplification and peridomestic mosquito vectors to cause major epidemics. here, i review these urban emergences and potential strategies for their prevention and control. | 0 | 23910545 |
| modeling and biological control of mosquitoes. | models can be useful at many different levels when considering complex issues such as biological control of mosquitoes. at an early stage, exploratory models are valuable in exploring the characteristics of an ideal biological control agent and for guidance in data collection. when more data are available, models can be used to explore alternative control strategies and the likelihood of success. there are few modeling studies that explicitly consider biological control in mosquitoes; however, t ... | 0 | 17853610 |
| habitat segregation of mosquito arbovirus vectors in south florida. | oviposition traps set in rural to urban environments in three south florida counties were colonized predominantly by culex quinquefasciatus say (35.1%), aedes albopictus (skuse) (34.5%), aedes aegypti (l.) (23.8%), and culex nigripalpus theobald (6.6%) during 1 yr of monthly sampling. significant differences were detected among counties for abundances of cx. quinquefasciatus and for percentage composition of that species and ae. albopictus. aerial images of habitats around each collection site w ... | 0 | 17162945 |
| antiviral natural products and herbal medicines. | viral infections play an important role in human diseases, and recent outbreaks in the advent of globalization and ease of travel have underscored their prevention as a critical issue in safeguarding public health. despite the progress made in immunization and drug development, many viruses lack preventive vaccines and efficient antiviral therapies, which are often beset by the generation of viral escape mutants. thus, identifying novel antiviral drugs is of critical importance and natural produ ... | 0 | 24872930 |
| interspecific competition of a new invasive mosquito, culex coronator, and two container mosquitoes, aedes albopictus and cx. quinquefasciatus (diptera: culicidae), across different detritus environments. | the mosquito culex coronator (dyar and knab) (diptera: culicidae) has undergone rapid range expansion in the united states since 2003, with its historical distribution in the southwest expanding eastward to the atlantic coast. although cx. coronator nominally use small natural aquatic habitats for development, the use of containers (e.g., tires) makes it potentially important as container invasive. to determine the potential ecological effects of cx. coronator on resident container species, we c ... | 0 | 24605457 |
| history, epidemiology, and clinical manifestations of zika: a systematic review. | to describe salient epidemiological characteristics of zika virus outbreaks across the world and to examine the clinical presentations, complications, and atypical manifestations related to their occurrence in recent history. | 0 | 26959260 |
| zika virus: a global threat to humanity: a comprehensive review and current developments. | at present, one of greatest concerns of medical personnel is zika virus (zikv). though it has been reported for quite a long time, its rapid emergence, new modes of transmission, and more importantly, the congenital anomalies associated with it have made the situation worse. it was first detected in 1947. after that, this infection was found in the countries of africa as well as asia. at present, interestingly it has been reported from brazil. microcephaly and intracranial calcification have bee ... | 0 | 27114968 |
| dengue in the context of "safe blood" and global epidemiology: to screen or not to screen? | 0 | 22882092 | |
| virus evolution and transmission in an ever more connected world. | the frequency and global impact of infectious disease outbreaks, particularly those caused by emerging viruses, demonstrate the need for a better understanding of how spatial ecology and pathogen evolution jointly shape epidemic dynamics. advances in computational techniques and the increasing availability of genetic and geospatial data are helping to address this problem, particularly when both information sources are combined. here, we review research at the intersection of evolutionary biolog ... | 0 | 26702033 |
| genomic screening with rnai: results and challenges. | rna interference (rnai) is an effective tool for genome-scale, high-throughput analysis of gene function. in the past five years, a number of genome-scale rnai high-throughput screens (htss) have been done in both drosophila and mammalian cultured cells to study diverse biological processes, including signal transduction, cancer biology, and host cell responses to infection. results from these screens have led to the identification of new components of these processes and, importantly, have also ... | 0 | 20367032 |
| facts and ideas from anywhere. | 0 | 16369660 | |
| peripheral coding of taste. | five canonical tastes, bitter, sweet, umami (amino acid), salty, and sour (acid), are detected by animals as diverse as fruit flies and humans, consistent with a near-universal drive to consume fundamental nutrients and to avoid toxins or other harmful compounds. surprisingly, despite this strong conservation of basic taste qualities between vertebrates and invertebrates, the receptors and signaling mechanisms that mediate taste in each are highly divergent. the identification over the last two ... | 0 | 24607224 |
| volatile phytochemicals as mosquito semiochemicals. | plant biochemical processes result in the release of an array of volatile chemical substances into the environment, some of which are known to play important plant fitness enhancing functions, such as attracting pollinators, thermal tolerance of photosynthesis, and defense against herbivores. cunningly, phytophagous insects have evolved mechanisms to utilize these volatiles to their own advantage, either to colonize a suitable host for feeding, reproduction and oviposition or avoid an unsuitable ... | 0 | 25383131 |
| evaluation of a stable isotope method to mark naturally-breeding larval mosquitoes for adult dispersal studies. | understanding mosquito dispersal is critically important for vector-borne disease control and prevention. mark-release-recapture methods using various marking techniques have made substantial contributions to the study of mosquito biology. however, the ability to mark naturally breeding mosquitoes noninvasively and with life-long retention has remained problematic. here, we describe a method to mark naturally breeding mosquitoes with stable isotopes. culex pipiens f. molestus mosquitoes were pro ... | 0 | 22308772 |
| dengue outbreak in key west, florida, usa, 2009. | after 3 dengue cases were acquired in key west, florida, we conducted a serosurvey to determine the scope of the outbreak. thirteen residents showed recent infection (infection rate 5%; 90% ci 2%-8%), demonstrating the reemergence of dengue in florida. increased awareness of dengue among health care providers is needed. | 0 | 22257471 |
| risk assessment for yellow fever in western and north-western provinces of zambia. | north-western and western provinces of zambia were reclassified as low-risk areas for yellow fever (yf). however, the current potential for yf transmission in these areas is unclear. | 0 | 25722614 |
| functional circadian clock genes are essential for the overwintering diapause of the northern house mosquito, culex pipiens. | the short day lengths of late summer are used to program the overwintering adult diapause (dormancy) of the northern house mosquito, culex pipiens. here, we investigated the role of clock genes in initiating this diapause and asked whether the circadian cycling of clock gene expression persists during diapause. we provide evidence that the major circadian clock genes continue to cycle throughout diapause and after diapause has been terminated. rna interference (rnai) was used to knock down the c ... | 0 | 25653422 |
| outsmarting olfaction: the next generation of mosquito repellents. | 0 | 16002364 | |
| passive prophylaxis with permethrin-treated tents reduces mosquito bites among north american summer campers. | over 2 million adolescents participate in summer-camp experiences, placing themselves at risk for mosquito-borne illness. insect repellent is recommended but often not used. it is unknown whether permethrin treatment of a location, such as a campsite, provides passive prophylaxis reducing mosquito bites among all persons in the immediate vicinity. | 0 | 15813141 |
| effects of ingested vertebrate-derived factors on insect immune responses. | during the process of blood feeding insect vectors are exposed to an array of vertebrate-derived blood factors ranging from byproducts of blood meal digestion to naturally occurring products in the blood including growth hormones, cytokines and factors derived from blood-borne pathogens themselves. in this review, we examine the ability of these ingested vertebrate blood factors to alter the innate pathogen defenses of insect vectors. the ability of these factors to modify the immune responses o ... | 0 | 25401083 |
| high degree of single nucleotide polymorphisms in california culex pipiens (diptera: culicidae) sensu lato. | resolution of systematic relationships among members of the culex pipiens (l.) complex has important implications for public health as well as for studies on the evolution of sibling species. currently held views contend that in california considerable genetic introgression occurs between cx. pipiens and cx. quinquefasciatus say, and as such, these taxa behave as if they are a single species. development of high throughput snp genotyping tools for the analysis of cx. pipiens complex population s ... | 0 | 22493847 |
| no evolutionary response to four generations of laboratory selection on antipredator behavior of aedes albopictus: potential implications for biotic resistance to invasion. | aedes albopictus (skuse) is an invasive container-dwelling mosquito and an important disease vector that co-occurs with the native mosquito, aedes triseriatus (say), and the predatory midge, corethrella appendiculata (grabham). larval ae. triseriatus show significantly greater antipredatory responses when compared to larval ae. albopictus in the presence of predation cues from c. appendiculata. the potential for evolution of antipredatory behavioral responses to c. appendiculata in ae. albopictu ... | 0 | 19645279 |
| emerging and re-emerging viruses in the era of globalisation. | 0 | 19657478 | |
| towards a hybrid agent-based model for mosquito borne disease. | agent-based models (abm) are used to simulate the spread of infectious disease through a population. detailed human movement, demography, realistic business location networks, and in-host disease progression are available in existing abms, such as the epidemic simulation system (episims). these capabilities make possible the exploration of pharmaceutical and non-pharmaceutical mitigation strategies used to inform the public health community. there is a similar need for the spread of mosquito bor ... | 0 | 26618203 |
| chikungunya virus as cause of febrile illness outbreak, chiapas, mexico, 2014. | since chikungunya virus (chikv) was introduced into the americas in 2013, its geographic distribution has rapidly expanded. of 119 serum samples collected in 2014 from febrile patients in southern mexico, 79% were positive for chikv or igm against chikv. sequencing results confirmed chikv strains closely related to caribbean isolates. | 0 | 26488312 |
| symbionts conferring resistance to viruses in insects. | 0 | 25417905 | |
| false-negative dengue cases in roraima, brazil: an approach regarding the high number of negative results by ns1 ag kits. | serum samples from 150 ns1-negative (platelia elisa) patients presumptively diagnosed with dengue were analyzed by the taqman probed real-time reverse transcription pcr (taqman qrt-pcr) method. the qrt-pcr positive samples were tested for serotype by semi-nested rt-pcr and a qualitative immunochromatographic assay for igg and igm. molecular detection methods showed 33 (22%) positive samples out of 150 ns1-antigen negative samples. of these, 72% were collected up to day 2 after the onset of sympt ... | 0 | 25229228 |
| clinicohematological profiles of hospitalized patients with dengue in kolkata in 2012 epidemic, west bengal. | dengue usually presents itself with subclinical or mild infection to full blown dengue fever (df) to dengue hemorrhagic fever (dhf) and dengue shock syndrome (dss). in kolkata, dengue started in 1824 followed by five epidemics that occurred in 1836, 1906, 1911, 1923 and 2005. the aim of this investigation is to study the clinicohematological correlation of all patients with respect to their gender that were admitted to "kali pada chowdhury medical college and hospital" during 2012 epidemic. amon ... | 0 | 25242847 |
| assessing the risk of international spread of yellow fever virus: a mathematical analysis of an urban outbreak in asuncion, 2008. | yellow fever virus (yfv), a mosquito-borne virus endemic to tropical africa and south america, is capable of causing large urban outbreaks of human disease. with the ease of international travel, urban outbreaks could lead to the rapid spread and subsequent transmission of yfv in distant locations. we designed a stochastic metapopulation model with spatiotemporally explicit transmissibility scenarios to simulate the global spread of yfv from a single urban outbreak by infected airline travelers. ... | 0 | 22302873 |
| a case of yellow fever vaccine-associated viscerotropic disease in ecuador. | we report the first case of viscerotropic syndrome in ecuador. because of similarities between yellow fever and viscerotropic syndrome, the incidence of this recently described complication of vaccination with the 17d yellow fever vaccine is not known. there is a large population in south america that is considered at risk for possible reemergence of urban yellow fever. knowledge of potentially fatal complications of yellow fever vaccine should temper decisions to vaccinate populations where the ... | 0 | 20348528 |
| the deadly ebola threat in the midst of an overwhelming dengue epidemic. | the recent death tolls and morbidities associated with two deadly viral haemorrhagic fevers (vhfs), i.e., ebola and dengue, are simply shocking. by the end of august 2014, 65 672 people were afflicted with dengue fever (df) in malaysia, with 9505 from kelantan, and there were 128 reported deaths. more astounding are the death tolls associated with ebola: 3091 deaths from 6574 reported cases so far. it is not difficult to imagine the potential disaster if ebola spreads beyond africa. vhfs are cha ... | 0 | 25897277 |
| a three year retrospective study on the increasing trend in seroprevalence of dengue infection from southern odisha, india. | in odisha, several cases of dengue virus infection were detected for the first time in 2010, the importance of dengue as a serious mosquito-borne viral infection was felt only in 2011 with the reporting of many more positive cases. this retrospective three year study was done to find out the seroprevalence of dengue ig m0 antibody and to know the predominant serotype of dengue virus among the patients suspected to have dengue virus infection in a tertiary care hospital in southern odisha, india. | 0 | 25579149 |
| emerging arboviruses and public health challenges in brazil. | environmental modification by anthropogenic actions, disordered urban growth, globalization of international exchange and climate change are some factors that help the emergence and dissemination of human infectious diseases transmitted by vectors. this review discusses the recent entry of three arboviruses in brazil: chikungunya, west nile, and zika virus, focusing on the challenges for the country's public health. the brazilian population is exposed to infections caused by these three arboviru ... | 0 | 27355468 |
| climate and human health: the impact of climate change on vector-borne diseases, paphos, cyprus (17-19 october 2012). | 0 | 24428826 | |
| microhabitat partitioning of aedes simpsoni (diptera: culicidae). | yellow fever virus is a reemerging infection responsible for widespread, sporadic outbreaks across africa. although aedes aegypti (l.) is the most important vector globally, in east africa, epidemics may be vectored by aedes bromeliae (theobald), a member of the aedes simpsoni (theobald) species complex. the ae. simpsoni complex contains 10 subspecies, of which ae. bromeliae alone has been incriminated as a vector of yellow fever virus. however, morphological markers cannot distinguish ae. brome ... | 0 | 24897852 |
| zika. an emerging teratogenic virus. | [no abstract available]. | 0 | 27464857 |
| the global distribution of yellow fever and dengue. | yellow fever has been subjected to partial control for decades, but there are signs that case numbers are now increasing globally, with the risk of local epidemic outbreaks. dengue case numbers have also increased dramatically during the past 40 years and different serotypes have invaded new geographical areas. despite the temporal changes in these closely related diseases, and their enormous public health impact, few attempts have been made to collect a comprehensive dataset of their spatial an ... | 0 | 16647971 |
| evolutionary and ecological characterization of mayaro virus strains isolated during an outbreak, venezuela, 2010. | in 2010, an outbreak of febrile illness with arthralgic manifestations was detected at la estación village, portuguesa state, venezuela. the etiologic agent was determined to be mayaro virus (mayv), a reemerging south american alphavirus. a total of 77 cases was reported and 19 were confirmed as seropositive. mayv was isolated from acute-phase serum samples from 6 symptomatic patients. we sequenced 27 complete genomes representing the full spectrum of mayv genetic diversity, which facilitated de ... | 0 | 26401714 |
| phylogeography of dengue virus serotype 4, brazil, 2010-2011. | dengue virus serotype 4 (denv-4) reemerged in roraima state, brazil, 28 years after it was last detected in the country in 1982. to study the origin and evolution of this reemergence, full-length sequences were obtained for 16 denv-4 isolates from northern (roraima, amazonas, pará states) and northeastern (bahia state) brazil during the 2010 and 2011 dengue virus seasons and for an isolate from the 1982 epidemic in roraima. spatiotemporal dynamics of denv-4 introductions in brazil were applied t ... | 0 | 23092706 |
| co-circulation of dengue and chikungunya viruses, al hudaydah, yemen, 2012. | we investigated 400 cases of dengue-like illness in persons hospitalized during an outbreak in al hudaydah, yemen, in 2012. overall, 116 dengue and 49 chikungunya cases were diagnosed. dengue virus type 2 was the predominant serotype. the co-circulation of these viruses indicates that mosquitoborne infections represent a public health threat in yemen. | 0 | 25061762 |
| reply to skalsky et al.: a microrna-like small rna from dengue virus. | 0 | 25061641 | |
| small bite, big threat: the burden of vector-borne diseases. | 0 | 25909072 | |
| clinical applicability of various dengue diagnostic tests in resource-limited endemic settings. | dengue is one of the most important arboviral infections caused by one of the four dengue serotypes, 1-4. | 0 | 25191051 |
| zika virus infection after travel to tahiti, december 2013. | 0 | 25062427 | |
| vertical transmission of dengue virus in aedes aegypti collected in puerto iguazú, misiones, argentina. | a finding of vertical transmission of the den 3 virus in male specimens of aedes aegypti, collected in the 2009 fall-winter period, in puerto iguazú city, misiones, argentina, using the rt-pcr technique in a 15-specimen pool is reported. this result is analyzed within the context of the epidemiological situation of argentina's northeast border. | 0 | 24626420 |
| mosquito larvicidal properties of mirabilis jalapa (nyctaginaceae) against anopheles stephensi, aedes aegypti & culex quinquefasciatus (diptera: culicidae). | 0 | 25366214 | |
| updating the geographical distribution and frequency of aedes albopictus in brazil with remarks regarding its range in the americas. | the geographical distribution of aedes albopictus in brazil was updated according to the data recorded across the country over the last eight years. countrywide house indexes (hi) for ae. albopictus in urban and suburban areas were described for the first time using a sample of brazilian municipalities. this mosquito is currently present in at least 59% of the brazilian municipalities and in 24 of the 27 federal units (i.e., 26 states and the federal district). in 34 brazilian municipalities, th ... | 0 | 25317707 |
| imported dengue fever in tuscany, italy, in the period 2006 to 2012. | this report focuses on epidemiological and clinical features of dengue fever (df) in tuscany (italy) between 2006 and 2012. sixty-one df cases were diagnosed, 32 of which were in the period of aedes albopictus activity. some clinical (arthralgia/myalgia, nausea/vomiting, and skin rash), laboratory (leukopenia and thrombocytopenia), and epidemiological characteristics (travel in a continent other than africa) significantly distinguished df cases from other febrile illnesses. our data stress the i ... | 0 | 25155927 |
| molecular epidemiology and phylogenetic analysis of dengue virus type-1 and 2 isolated in malaysia. | detection of different serotypes of dengue virus and provide information on origin, distribution and genotype of the virus. | 0 | 26150855 |
| re-emergence of dengue virus serotype 2 strains in the 2013 outbreak in nepal. | epidemiological interventions and mosquito control are the available measures for dengue control. the former approach uses serotype and genetic information on the circulating virus strains. dengue has been frequently reported from nepal, but this information is mostly lacking. the present study was done to generate a comprehensive clinical and virological picture of a dengue outbreak in nepal during 2013. | 0 | 26905233 |
| reemergence and autochthonous transmission of dengue virus, eastern china, 2014. | in 2014, 20 dengue cases were reported in the cities of wenzhou (5 cases) and wuhan (15 cases), china, where dengue has rarely been reported. dengue virus 1 was detected in 4 patients. although most of these cases were likely imported, epidemiologic analysis provided evidence for autochthonous transmission. | 0 | 26292098 |
| molecular detection and typing of dengue viruses from archived tissues of fatal cases by rt-pcr and sequencing: diagnostic and epidemiologic implications. | diagnosis of dengue virus (denv) infection in fatal cases is challenging because of the frequent unavailability of blood or fresh tissues. for formalin-fixed, paraffin-embedded (ffpe) tissues immunohistochemistry (ihc) can be used; however, it may not be as sensitive and serotyping is not possible. the application of reverse transcription-polymerase chain reaction (rt-pcr) for the detection of denv in ffpe tissues has been very limited. we evaluated ffpe autopsy tissues of 122 patients with susp ... | 0 | 22302871 |
| deadly intracranial bleed in patients with dengue fever: a series of nine patients and review of literature. | dengue fever is a global pandemic threat with increasing incidence. to date, there are no cures and the effectiveness of dengue vaccines is still uncertain. world heath organization introduced expanded dengue syndrome to include unusual presentations of dengue fever including severe neurologic complications. one of the deadly complications is intracranial hemorrhage (ich). | 0 | 27365962 |