Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| advances in developing a climate based dengue outbreak models in dhaka, bangladesh: challenges & opportunities. | 0 | 22885257 | |
| cadherin binding is not a limiting step for bacillus thuringiensis subsp. israelensis cry4ba toxicity to aedes aegypti larvae. | bacillus thuringiensis subsp. israelensis produces three cry toxins (cry4aa, cry4ba and cry11aa) that are active against aedes aegypti larvae. the identification of the rate-limiting binding steps of cry toxins that are used for insect control in the field, such as those of b. thuringiensis subsp. israelensis, should provide targets for improving insecticides against important insect pests. previous studies showed that cry11aa binds to cadherin receptor fragment cr7-11 (cadherin repeats 7-11) wi ... | 0 | 22329749 |
| analysis of lipolysis underlying lactation in the tsetse fly, glossina morsitans. | female tsetse flies undergo viviparous reproduction, generating one larva each gonotrophic cycle. larval nourishment is provided by the mother in the form of milk secretions. the milk consists mostly of lipids during early larval development and shifts to a balanced combination of protein and lipids in the late larval instars. provisioning of adequate lipids to the accessory gland is an indispensable process for tsetse fecundity. this work investigates the roles of brummer lipase (bmm) and the a ... | 0 | 22509523 |
| a review on the toxicity and non-target effects of macrocyclic lactones in terrestrial and aquatic environments. | the avermectins, milbemycins and spinosyns are collectively referred to as macrocyclic lactones (mls) which comprise several classes of chemicals derived from cultures of soil micro-organisms. these compounds are extensively and increasingly used in veterinary medicine and agriculture. due to their potential effects on non-target organisms, large amounts of information on their impact in the environment has been compiled in recent years, mainly caused by legal requirements related to their marke ... | 0 | 22039795 |
| dengue infections in travellers. | dengue has been designated a major international public health problem by the world health organization (who). it is endemic in most tropical and sub-tropical countries, which are also popular tourist destinations. travellers are not only at significant risk of acquiring dengue but they also contribute to its spread to non-endemic regions. furthermore, they may serve as sentinels to alert the international community to epidemics in dengue-endemic regions. geosentinel, a global surveillance netwo ... | 0 | 22668447 |
| dengue: an escalating public health problem in latin america. | dengue infection is a significant and escalating public health problem in latin america. its re-emergence and subsequent rise in the region over the past 50 years has largely been caused by a combination of a lack of political will, the radical growth of urban populations, migration flow and insufficient financial resources. its increased incidence has been compounded by climate change, poor sanitation and extreme poverty, which lead to more breeding sites of the mosquito vector aedes aegypti. i ... | 0 | 22668444 |
| the dengue situation in africa. | dengue outbreaks and epidemics have been reported in all regions of africa, and it is believed that all four dengue virus serotypes are in circulation. available data suggest that dengue is endemic to 34 african countries and that aedes aegypti mosquitoes--the primary vector for dengue transmission--are known to be present in all but five countries. whether populations in africa are susceptible to dengue at the same rates as in asia and latin america is difficult to determine from the available ... | 0 | 22668445 |
| infertility resulting from transgenic i-ppoi male anopheles gambiae in large cage trials. | anopheles gambiae is the primary vector of malaria in sub-saharan africa and is a potential target of genetic control programs. we determined the capacity of male a. gambiae created by germline transformation to introduce infertility into stable age-distribution populations. we also determined effects of the transgenes on life history. | 0 | 22595271 |
| the effect of ivermectin in seven strains of aedes aegypti (diptera: culicidae) including a genetically diverse laboratory strain and three permethrin resistant strains. | seven different strains of aedes aegypti (l.), including a genetically diverse laboratory strain, three laboratory-selected permethrin-resistant strains, a standard reference strain, and two recently colonized strains were fed on human blood containing various concentrations of ivermectin. ivermectin reduced adult survival, fecundity, and hatch rate of eggs laid by ivermectin-treated adults in all seven strains. the lc50 of ivermectin for adults and the concentration that prevented 50% of eggs f ... | 0 | 22493855 |
| study on the correlation of premises condition index and the presence of larvae of aedes species mosquitoes in human dwellings of the cuddalore district of tamil nadu, india. | it is concluded that this study helps in conducting rapid survey to identify the presence of aedes larvae with a minimum number of staff for both inspection and treatment of aedes larvae during the epidemic situation. | 0 | 24159479 |
| mosquitocidal properties of natural product compounds isolated from chinese herbs and synthetic analogs of curcumin. | because of resistance to current insecticides and to environmental, health, and regulatory concerns, naturally occurring compounds and their derivatives are of increasing interest for the development of new insecticidal compounds against vectors of disease-causing pathogens. fifty-eight compounds, either extracted and purified from plants native to china or synthetic analogs of curcumin, were evaluated for both their larvicidal activity against aedes aegypti (l.) and their ability to inhibit bin ... | 0 | 22493854 |
| mutually exclusive splicing of the insect dscam pre-mrna directed by competing intronic rna secondary structures. | drosophila dscam encodes 38,016 distinct axon guidance receptors through the mutually exclusive alternative splicing of 95 variable exons. importantly, known mechanisms that ensure the mutually exclusive splicing of pairs of exons cannot explain this phenomenon in dscam. i have identified two classes of conserved elements in the dscam exon 6 cluster, which contains 48 alternative exons--the docking site, located in the intron downstream of constitutive exon 5, and the selector sequences, which a ... | 0 | 16213213 |
| females use self-referent cues to avoid mating with previous mates. | females of many species mate repeatedly throughout their lives, often with many different males (polyandry). females can secure genetic benefits by maximizing their diversity of mating partners, and might be expected, therefore, to forego matings with previous partners in favour of novel males. indeed, a female preference for novel mating partners has been shown in several taxa, but the mechanism by which females distinguish between novel males and previous mates remains unknown. we show that fe ... | 0 | 16271971 |
| cloning and expression analysis of the bombyx mori α-amylase gene (amy) from the indigenous thai silkworm strain, nanglai. | α-amylase is a common enzyme for hydrolyzing starch. in the silkworm, bombyx mori l. (lepidoptera: bombycidae), α-amylase is found in both digestive fluid and hemolymph. here, the complete genomic sequence of the amy gene encoding α-amylase from a local thai silkworm, the nanglai strain, was obtained. this gene was 7981 bp long with 9 exons. the full length amy cdna sequence was 1749 bp containing a 1503 bp open reading frame. the orf encoded 500 amino acid residues. the deduced protein showed 8 ... | 0 | 21529256 |
| proteome changes in the plasma of pieris rapae parasitized by the endoparasitoid wasp pteromalus puparum. | parasitism by the endoparasitoid wasp pteromalus puparum causes alterations in the plasma proteins of pieris rapae. analysis of plasma proteins using a proteomic approach showed that seven proteins were differentially expressed in the host pupae after 24-h parasitism. they were masquerade-like serine proteinase homolog (msph), enolase (eno), bilin-binding protein (bbp), imaginal disc growth factor (idgf), ornithine decarboxylase (odc), cellular retinoic acid binding protein (crabp), and one unkn ... | 0 | 21265041 |
| discrete pulses of molting hormone, 20-hydroxyecdysone, during late larval development of drosophila melanogaster: correlations with changes in gene activity. | periodic pulses of the insect steroid molting hormone 20-hydroxyecdysone (20e), acting via its nuclear receptor complex (ecr/usp), control gene expression at many stages throughout drosophila development. however, during the last larval instar of some lepidopteran insects, subtle changes in titers of ecdysteroids have been documented, including the so-called "commitment peak." this small elevation of 20e reprograms the larva for metamorphosis to the pupa. similar periods of ecdysteroid immunorea ... | 0 | 16273522 |
| the drosophila microrna iab-4 causes a dominant homeotic transformation of halteres to wings. | the drosophila bithorax complex encodes three well-characterized homeodomain proteins that direct segment identity, as well as several noncoding rnas of unknown function. here, we analyze the iab-4 locus, which produces the micrornas iab-4-5p and iab-4-3p. iab-4 is analogous to mir-196 in vertebrate hox clusters. previous studies demonstrate that mir-196 interacts with the hoxb8 3' untranslated region. evidence is presented that mir-iab-4-5p directly inhibits ubx activity in vivo. ectopic expres ... | 0 | 16357215 |
| light on the moth-eye corneal nipple array of butterflies. | the outer surface of the facet lenses in the compound eyes of moths consists of an array of excessive cuticular protuberances, termed corneal nipples. we have investigated the moth-eye corneal nipple array of the facet lenses of 19 diurnal butterfly species by scanning electron microscopy, transmission electron microscopy and atomic force microscope, as well as by optical modelling. the nipples appeared to be arranged in domains with almost crystalline, hexagonal packing. the nipple distances we ... | 0 | 16608684 |
| condition-specific competition in container mosquitoes: the role of noncompeting life-history stages. | condition-specific competition, wherein competitive superiority varies with the abiotic environment, can determine species' distributions in a spatially heterogeneous environment. we investigated this phenomenon with two competing container-dwelling mosquitoes. we tested the hypothesis that habitat drying alters the outcome of interspecific competition, predicting that the competitive impact of aedes albopictus on aedes aegypti would be severe in wetter environments, but greatly reduced in drier ... | 0 | 17450188 |
| location of and landing on a source of human body odour by female culex quinquefasciatus in still and moving air. | the orientation to and landing on a source of human odour by female culex quinquefasciatus say (diptera: culicidae) is observed in a wind tunnel without an airflow or with a laminar airflow of 0.2 m s(-1). odours from human feet are collected by 'wearing' clean glass beads inside a stocking and presenting beads in a petri dish in a wind tunnel. mosquitoes are activated by brief exposure to a 1 l min(-1) jet of 4% co2 positioned 10 cm from the release cage. in moving air at 0.2 m s(-1), a mean of ... | 0 | 26472918 |
| high level of awareness but poor practices regarding dengue fever control: a cross-sectional study from north india. | delhi, the capital of india, has suffered many outbreaks of dengue in recent past and despite the obvious magnitude of problem, very scarce evidence exists that documents the knowledge, awareness and practices of the people regarding dengue. | 0 | 22754880 |
| a vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. | vitellogenin (vg) is an egg-yolk precursor protein in most oviparous species. in honeybee (apis mellifera), the protein (amvg) also affects social behavior and life-span plasticity. despite its manifold functions, the amvg molecule remains poorly understood. the subject of our structure-oriented amvg study is its polyserine tract - a little-investigated repetitive protein segment mostly found in insects. we previously reported that amvg is tissue specifically cleaved in the vicinity of this trac ... | 0 | 22573762 |
| histone recognition and nuclear receptor co-activator functions of drosophila cara mitad, a homolog of the n-terminal portion of mammalian mll2 and mll3. | mll2 and mll3 histone lysine methyltransferases are conserved components of compass-like co-activator complexes. in vertebrates, the paralogous mll2 and mll3 contain multiple domains required for epigenetic reading and writing of the histone code involved in hormone-stimulated gene programming, including receptor-binding motifs, set methyltransferase, hmg and phd domains. the genes encoding mll2 and mll3 arose from a common ancestor. phylogenetic analyses reveal that the ancestral gene underwent ... | 0 | 22569554 |
| ecoepidemiologia del dengue: relevancia de dos vectores invasores. | 0 | 25284912 | |
| characterization of cry2-type genes of bacillus thuringiensis strains from soilisolated of sichuan basin, china. | sichuan basin, situated in the west of china, is the fourth biggest basin in china. in order to describe a systematic study of the cry2-type genes resources from bacillus thuringiensis strains of sichuan basin, a total of 791 bacillus thuringiensis strains have been screened from 2650 soil samples in different ecological regions. the method of pcr-restriction fragment length polymorphism (pcr-rflp) was used to identify the type of cry2 genes. the results showed that 322 bacillus thuringiensis st ... | 0 | 24031615 |
| bilateral premacular subhyaloid hemorrhage in dengue fever. | 0 | 22454709 | |
| sampling considerations for designing aedes aegypti (diptera:culicidae) oviposition studies in iquitos, peru: substrate preference, diurnal periodicity, and gonotrophic cycle length. | when devising methods to sample aedes aegypti (l.) eggs from naturally-occurring containers to investigate selective oviposition, failure to take into account certain aspects of ae. aegypti behavior can bias study inferences. in iquitos, peru, we tested three assumptions related to designing ae. aegypti oviposition field studies, as follows: 1) lining containers with paper as an oviposition substrate does not affect oviposition; 2) diurnal egg-laying activity peaks in the late afternoon or early ... | 0 | 21337947 |
| differential selection within the drosophila retinal determination network and evidence for functional divergence between paralog pairs. | the retinal determination (rd) network in drosophila comprises 14 known nuclear proteins that include dna-binding proteins, transcriptional coactivators, kinases, and phosphatases. the composition of the network varies considerably throughout the animal kingdom, with the network in several basal insects having fewer members and with vertebrates having potentially significantly higher numbers of rd genes. one important contributing factor for the variation in gene number within the network is gen ... | 0 | 21210943 |
| visceral leishmaniasis in far western nepal: another case and concerns about a new area of endemicity. | 0 | 21363996 | |
| male mating history and body size influence female fecundity and longevity of the dengue vector aedes aegypti. | male reproductive success is dependent on insemination success and reproductive output. during mating, male mosquitoes transfer not just sperm, but also seminal fluid proteins that may have profound effects on mated female biology and behavior. in this study, we investigated the role of male body size and mating history on semen depletion, female longevity, and reproductive success in aedes aegypti l. small and large males were mated in rapid succession with up to five females. our results indic ... | 0 | 21485355 |
| prevalence of chikungunya in urban field practice area of a private medical college, chennai. | the outbreak of chikungunya in india started during december 2005 with more than 11,00,000 cases. many cases with symptoms suggestive of chikungunya reported to our urban health-training centre. hence this study was done to estimate the prevalence of chikungunya, to study the common treatment-seeking behavior, control measures and the sequalae of chikungunya by follow-up. | 0 | 21976797 |
| infection dynamics of western equine encephalomyelitis virus (togaviridae: alphavirus) in four strains of culex tarsalis (diptera: culicidae): an immunocytochemical study. | background: vector competence describes the efficiency with which vector arthropods become infected with and transmit pathogens and depends on interactions between pathogen and arthropod genetics as well as environmental factors. for arbovirus transmission, the female mosquito ingests viremic blood, the virus infects and replicates in midgut cells, escapes from the midgut, and disseminates to other tissues, including the salivary glands. virus-laden saliva is then injected into a new host. for t ... | 0 | 22629118 |
| the poly(a) polymerase gld2 is required for spermatogenesis in drosophila melanogaster. | the dna of a developing sperm is normally inaccessible for transcription for part of spermatogenesis in many animals. in drosophila melanogaster, many transcripts needed for late spermatid differentiation are synthesized in pre-meiotic spermatocytes, but are not translated until later stages. thus, post-transcriptional control mechanisms are required to decouple transcription and translation during spermatogenesis. in the female germline, developing germ cells accomplish similar decoupling throu ... | 0 | 21427144 |
| upward trend in dengue incidence among hospitalized patients, united states. | international travel and a global expansion of dengue fever have the potential to increase the incidence of dengue in the united states. we conducted a retrospective cohort analysis of trends in dengue among hospitalized patients by using the national inpatient sample (2000-2007); the number of cases more than tripled (p<0.0001). | 0 | 21529411 |
| the cost of routine aedes aegypti control and of insecticide-treated curtain implementation. | insecticide-treated curtains (itcs) are promoted for controlling the dengue vector aedes aegypti. we assessed the cost of the routine aedes control program (racp) and the cost of itc implementation through the racp and health committees in venezuela and through health volunteers in thailand. the yearly cost of the racp per household amounted to us$2.14 and $1.89, respectively. the itc implementation cost over three times more, depending on the channel used. in venezuela the racp was the most eff ... | 0 | 21540384 |
| the mysterious multi-modal repellency of deet. | deet is the most effective insect repellent available and has been widely used for more than half a century. here, i review what is known about the olfactory and contact mechanisms of deet repellency. for mosquitoes, deet has at least two molecular targets: odorant receptors (ors) mediate the effect of deet at a distance, while unknown chemoreceptors mediate repellency upon contact. additionally, the ionotropic receptor ir40a has recently been identified as a putative deet chemosensor in drosoph ... | 0 | 26252744 |
| dengue reborn: widespread resurgence of a resilient vector. | 0 | 18795135 | |
| toxicity studies for indigenous bacillus thuringiensis isolates from malang city, east java on aedes aegypti larvae. | to investigate the toxicity of indigenous bacillus thuringiensis (b. thuringiensis)isolates from malang city for controlling aedes aegypti (ae. aegypti) larvae. | 0 | 23593589 |
| genome-level analysis of selective constraint without apparent sequence conservation. | conservation of function can be accompanied by obvious similarity of homologous sequences which may persist for billions of years (iyer lm, leipe dd, koonin ev, aravind l. 2004. evolutionary history and higher order classification of aaa+ atpases. j struct biol. 146:11-31.). however, presumably homologous segments of noncoding dna can also retain their ancestral function even after their sequences diverge beyond recognition (fisher s, grice ea, vinton rm, bessling sl, mccallion as. 2006. conserv ... | 0 | 23418180 |
| crystal structure and functional characterization of the human rbm25 pwi domain and its flanking basic region. | human rbm25 (rna-binding motif protein 25) is a novel splicing factor that contains a pwi domain, a newly identified rna/dna-binding domain, and regulates bcl-x pre-mrna alternative splicing. the flanking basic region has been suggested to serve as a co-operative partner of the pwi domain in the binding of nucleic acids, but the structure of this basic region is unknown. in the present paper, we report the crystal structure of the rbm25 pwi domain and its flanking basic region. the pwi domain is ... | 0 | 23190262 |
| evolutionary conservation and adaptation in the mechanism that regulates srebp action: what a long, strange trip it's been. | sterol regulatory element-binding proteins (srebps) are a subfamily of basic helix-loop-helix leucine zipper (bhlh-lz) transcription factors that are conserved from fungi to humans and are defined by two key features: a signature tyrosine residue in the dna-binding domain, and a membrane-tethering domain that is a target for regulated proteolysis. recent studies including genome-wide and model organism approaches indicate srebps coordinate cellular lipid metabolism with other cellular physiologi ... | 0 | 19933148 |
| larvicidal activity of syzygium aromaticum (l.) merr and citrus sinensis (l.) osbeck essential oils and their antagonistic effects with temephos in resistant populations of aedes aegypti. | environmentally friendly botanical larvicides are commonly considered as an alternative to synthetic larvicides against aedes aegypti linn. in addition, mosquito resistance to currently used larvicides has motivated research to find new compounds acting via different mechanisms of action, with the goal of controlling the spread of mosquitos. essential oils have been widely studied for this purpose. this work aims to evaluate the larvicidal potential of syzygium aromaticum and citrus sinensis ess ... | 0 | 27384083 |
| the efficacy of some commercially available insect repellents for aedes aegypti (diptera: culicidae) and aedes albopictus (diptera: culicidae). | reducing the number of host-vector interactions is an effective way to reduce the spread of vector-borne diseases. repellents are widely used to protect humans from a variety of protozoans, viruses, and nematodes. deet (n,n-diethyl-meta-toluamide), a safe and effective repellent, was developed during world war ii. fear of possible side effects of deet has created a large market for "natural" deet-free repellents with a variety of active ingredients. we present a comparative study on the efficacy ... | 0 | 26443777 |
| big city, small world: density, contact rates, and transmission of dengue across pakistan. | macroscopic descriptions of populations commonly assume that encounters between individuals are well mixed; i.e. each individual has an equal chance of coming into contact with any other individual. relaxing this assumption can be challenging though, due to the difficulty of acquiring detailed knowledge about the non-random nature of encounters. here, we fitted a mathematical model of dengue virus transmission to spatial time-series data from pakistan and compared maximum-likelihood estimates of ... | 0 | 26468065 |
| draft genome sequence of bacillus thuringiensis 147, a brazilian strain with high insecticidal activity. | bacillus thuringiensis is a ubiquitous gram-positive and sporulating bacterium. its crystals and secreted toxins are useful tools against larvae of diverse insect orders and, as a consequence, an alternative to recalcitrant chemical insecticides. we report here the draft genome sequence of b. thuringiensis147, a strain isolated from brazil and with high insecticidal activity. the assembled genome contained 6,167,994 bp and was distributed in seven replicons (a chromosome and 6 plasmids). we iden ... | 0 | 26517667 |
| satyrization without evidence of successful insemination from interspecific mating between invasive mosquitoes. | previous research has documented low frequencies of interspecific mating in nature between the invasive vectors aedes aegypti and aedes albopictus. it is also known that heterospecific male accessory gland substances transferred during mating sterilize a. aegypti but not a. albopictus females, leading to satyrization, a form of reproductive interference. this paper demonstrates that satyrization of a. aegypti by a. albopictus may occur without evidence of successful insemination. our results sho ... | 0 | 26382076 |
| inhibitor designing, virtual screening, and docking studies for methyltransferase: a potential target against dengue virus. | aim of this work was to design and identify some s-adenosyl-l-homocysteine (sah) analogs as inhibitors of s-adenosyl-l-methionine-dependent methyltransferase (mtase) protein using computational approaches. | 0 | 27413346 |
| [dengue and chikungunya vector control: is it necessary to re-examine present strategies?]. | 0 | 26849689 | |
| modelling, simulation and social network data: what's new for public health and epidemiology informatics? | 0 | 26293870 | |
| it's time for doctors to speak out on climate change. | 0 | 22135506 | |
| cell surface changes in the egg at fertilization. | an egg changes dramatically at fertilization. these changes include its developmental potential, its physiology, its gene expression profile, and its cell surface. this review highlights the changes in the cell surface of the egg that occur in response to sperm. these changes include modifications to the extracellular matrix, to the plasma membrane, and to the secretory vesicles whose contents direct many of these events. in some species, these changes occur within minutes of fertilization, and ... | 0 | 19658159 |
| chikungunya fever - epidemic in rural maharashtra. | 0 | 20165644 | |
| promising new tools to fight aedes mosquitoes. | two new tools for suppressing aedes aegypti mosquito populations have been recommended for pilot testing. carefully designed trials will be needed to see whether they actually reduce disease as well. andréia azevedo soares reports. | 0 | 27516632 |
| racing against time against zika. | 0 | 27489331 | |
| vaccine-preventable diseases in humanitarian emergencies among refugee and internally-displaced populations. | humanitarian emergencies may result in breakdown of regular health services including routine vaccination programs. displaced populations including refugees and internally displaced persons are particularly susceptible to outbreaks of communicable diseases such as vaccine-preventable diseases (vpds). common vpds encountered in humanitarian emergencies include measles, polio, and depending on geographical location, meningococcal meningitis, yellow fever, hepatitis a, and cholera. we conducted a r ... | 0 | 26406333 |
| clip-domain serine proteases as immune factors in insect hemolymph. | clip proteases are non-digestive serine proteases present in hemolymph of insects and other arthropods. they are composed of one or more amino-terminal clip domains followed by a linker sequence and a carboxyl-terminal s1a family serine protease domain. the genes for clip proteases have evolved as four clades (clipa, clipb, clipc, clipd), each present as multigene families in insect genomes. clip proteases in hemolymph function in innate immune responses. these include proteolytic activation of ... | 0 | 26688791 |
| nutritional control of insect reproduction. | the amino acid-target of rapamycin (aa/tor) and insulin pathways play a pivotal role in reproduction of female insects, serving as regulatory checkpoints that guarantee the sufficiency of nutrients for developing eggs. being evolutionary older, the aa/tor pathway functions as an initial nutritional sensor that not only activates nutritional responses in a tissue-specific manner, but is also involved in the control of insect insulin-like peptides (ilps) secretion. insulin and aa/tor pathways also ... | 0 | 26644995 |
| repellant and insecticidal activities of shyobunone and isoshyobunone derived from the essential oil of acorus calamus rhizomes. | it was found that the essential oil of acorus calamus rhizomes showed insecticidal activity. | 0 | 26600710 |
| molecular analysis of juvenile hormone analog action in controlling the metamorphosis of the red flour beetle, tribolium castaneum. | the juvenile hormone analogs (jha) are known to disrupt insect development but the molecular mechanisms of their action have been studied only in a few model insects belonging to orders diptera and lepidoptera. here, we investigated the mechanisms of jha action in red flour beetle, tribolium castaneum, belonging to the order coleoptera. application of jha during penultimate and final instar larval stages blocked larval-pupal metamorphosis and induced supernumerary larval molts. when compared to ... | 0 | 19072925 |
| screening of uruguayan plants for deterrent activity against insects. | we evaluated the anti-insectan activity of extracts from different vegetative parts of ten plant species native to uruguay. the selected plants belong to five families: bignoniaceae: clytostoma callistegioides, dolichandra cynanchoides, macfadyena unguis-cati; sapindaceae: dodonaea viscosa, allophylus edulis, serjania meridionalis; lamiaceae: salvia procurrens, salvia guaranitica; solanaceae: lycium cestroides; and phytolaccaceae: phytolacca dioica. the extracts were evaluated in independent bio ... | 0 | 20046902 |
| awareness and support of release of genetically modified "sterile" mosquitoes, key west, florida, usa. | after a dengue outbreak in key west, florida, during 2009-2010, authorities, considered conducting the first us release of male aedes aegypti mosquitoes genetically modified to prevent reproduction. despite outreach and media attention, only half of the community was aware of the proposal; half of those were supportive. novel public health strategies require community engagement. | 0 | 25625795 |
| use of insecticide-treated house screens to reduce infestations of dengue virus vectors, mexico. | dengue prevention efforts rely on control of virus vectors. we investigated use of insecticide-treated screens permanently affixed to windows and doors in mexico and found that the screens significantly reduced infestations of aedes aegypti mosquitoes in treated houses. our findings demonstrate the value of this method for dengue virus vector control. | 0 | 25625483 |
| integrating participatory community mobilization processes to improve dengue prevention: an eco-bio-social scaling up of local success in machala, ecuador. | this project investigates the effectiveness and feasibility of scaling-up an eco-bio-social approach for implementing an integrated community-based approach for dengue prevention in comparison with existing insecticide-based and emerging biolarvicide-based programs in an endemic setting in machala, ecuador. | 0 | 25604763 |
| effectiveness and feasibility of long-lasting insecticide-treated curtains and water container covers for dengue vector control in colombia: a cluster randomised trial. | long-lasting insecticide-treated net (llin) window and door curtains alone or in combination with llin water container covers were analysed regarding effectiveness in reducing dengue vector density, and feasibility of the intervention. | 0 | 25604762 |
| long-lasting insecticide-treated house screens and targeted treatment of productive breeding-sites for dengue vector control in acapulco, mexico. | long-lasting insecticidal net screens (llis) fitted to domestic windows and doors in combination with targeted treatment (tt) of the most productive aedes aegypti breeding sites were evaluated for their impact on dengue vector indices in a cluster-randomised trial in mexico between 2011 and 2013. | 0 | 25604761 |
| entomological impact and social participation in dengue control: a cluster randomized trial in fortaleza, brazil. | this study intended to implement a novel intervention strategy, in brazil, using an ecohealth approach and analyse its effectiveness and costs in reducing aedes aegypti vector density as well as its acceptance, feasibility and sustainability. the intervention was conducted from 2012 to 2013 in the municipality of fortaleza, northeast brazil. | 0 | 25604760 |
| improved dengue fever prevention through innovative intervention methods in the city of salto, uruguay. | uruguay is located at the southern border of aedes aegypti distribution on the south american sub-continent. the reported dengue cases in the country are all imported from surrounding countries. one of the cities at higher risk of local dengue transmission is salto, a border city with heavy traffic from dengue endemic areas. | 0 | 25604764 |
| a lepidopteran orthologue of reaper reveals functional conservation and evolution of iap antagonists. | genetic studies in drosophila melanogaster have revealed that inhibitor of apoptosis (iap) proteins and iap antagonists such as reaper play a pivotal role in controlling cell death in insects. interestingly, although the sequences and structures of iaps are highly conserved, the sequence of iap antagonists diverged very rapidly during evolution, making their identification difficult. using a customized bioinformatics approach, we identified an iap antagonist, iap-binding motif 1 (ibm1), from the ... | 0 | 19523066 |
| wolbachia endosymbiont of brugia malayi elicits a t helper type 17-mediated pro-inflammatory immune response through wolbachia surface protein. | wolbachia is an endosymbiotic bacterium of the filarial nematode brugia malayi. the symbiotic relationship between wolbachia and its filarial host is dependent on interactions between the proteins of both organisms. however, little is known about wolbachia proteins that are involved in the inflammatory pathology of the host during lymphatic filariasis. in the present study, we cloned, expressed and purified wolbachia surface protein (r-wsp) from wolbachia and administered it to mice, either alon ... | 0 | 25059495 |
| disruption of dengue virus transmission by mosquitoes. | current control efforts for mosquito-borne arboviruses focus on mosquito control involving insecticide applications, which are becoming increasingly ineffective and unsustainable in urban areas. mosquito population replacement is an alternative arbovirus control concept aiming at replacing virus-competent vector populations with laboratory-engineered incompetent vectors. a prerequisite for this strategy is the design of robust anti-pathogen effectors that can ultimately be genetically driven thr ... | 0 | 26120563 |
| aversion and attraction through olfaction. | sensory cues that predict reward or punishment are fundamental drivers of animal behavior. for example, attractive odors of palatable food or a potential mate predict reward, while aversive odors of pathogen-laced food or a predator predict punishment. aversive and attractive odors can be detected by intermingled sensory neurons that express highly related olfactory receptors and display similar central projections. these findings raise basic questions of how innate odor valence is extracted fro ... | 0 | 25649823 |
| chikungunya on the move. | in december 2013, chikungunya virus (chikv) transmission was reported for the first time in the americas. since then it has spread quickly, with more than 1 million suspected and confirmed cases being reported in one year, where previously there were only sporadic travel-related cases. transmission patterns suggest that the epidemic in the southern hemisphere is only beginning and that chikungunya will not go away anytime soon. | 0 | 25649340 |
| voltage coupling of primary h+ v-atpases to secondary na+- or k+-dependent transporters. | this review provides alternatives to two well established theories regarding membrane energization by h(+) v-atpases. firstly, we offer an alternative to the notion that the h(+) v-atpase establishes a protonmotive force (pmf) across the membrane into which it is inserted. the term pmf, which was introduced by peter mitchell in 1961 in his chemiosmotic hypothesis for the synthesis of atp by h(+) f-atp synthases, has two parts, the electrical potential difference across the phosphorylating membra ... | 0 | 19448072 |
| chloroquine use improves dengue-related symptoms. | dengue is the most important arboviral disease in the world. as chloroquine, an antimalarial agent, has shown some antiviral effects, this study evaluated its effect in patients with dengue. a randomised, double-blind study was performed by administering chloroquine or placebo for three days to 129 patients with dengue-related symptoms. of these patients, 37 were confirmed as having dengue and completed the study; in total, 19 dengue patients received chloroquine and 18 received placebo. there w ... | 0 | 23903975 |
| oral delivery of double-stranded rna in larvae of the yellow fever mosquito, aedes aegypti: implications for pest mosquito control. | rna interference has already proven itself to be a highly versatile molecular biology tool for understanding gene function in a limited number of insect species, but its widespread use in other species will be dependent on the development of easier methods of double-stranded rna (dsrna) delivery. this study demonstrates that rna interference can be induced in the mosquito aedes aegypti l. (diptera: culicidae) simply by soaking larvae in a solution of dsrna for two hours. the mrna transcripts for ... | 0 | 24224468 |
| dengue: "plus ça change, plus c'est la même chose". | 0 | 24600111 | |
| influence of age and nutritional status on flight performance of the asian tiger mosquito aedes albopictus (diptera: culicidae). | the asian tiger mosquito, aedes albopictus, is a competent vector for arboviruses and recently was implicated as the vector of the first autochthonous cases of dengue and chikungunya in southern europe. the objective of this study was to analyze the flight performance of female ae. albopictus of different ages that were starved, sugar-fed, or sugar-fed and blood-fed, using flight mills. after three days of starvation post emergence, females flew an average distance of 0.7 ± 0.5 km in 1.9 ± 1.5 h ... | 0 | 24404384 |
| an extraovarian protein accumulated in mosquito oocytes is a carboxypeptidase activated in embryos. | we report a phenomenon previously unknown for oviparous animals; in aedes aegypti mosquitoes a serine carboxypeptidase is synthesized extraovarially and then internalized by oocytes. the cdna encoding mosquito vitellogenic carboxypeptidase (vcp) was cloned and sequenced. the vcp cdna hybridizes to a 1.5-kilobase mrna present only in the fat body of vitellogenic females. the deduced amino acid sequence of vcp shares significant homology with members of the serine carboxypeptidase family. binding ... | 0 | 1961751 |
| polyamine synthesis by the mermithid nematode romanomermis culicivorax. | the polyamine and amino acid composition of the mermithid nematode, romanomermis culicivorax, and its host, aedes aegypti, was determined. putrescine, spermidine, spermine, cadaverine and two acetylated spermidine derivatives were present in parasitic juveniles, newly-emerged post-parasites, and eggs of r. culicivorax. whole insect homogenates of fourth-instar a. aegypti contained the same array of polyamines, except that the putrescine:spermidine ratio was the inverse of that in parasitic r. cu ... | 0 | 19287579 |
| what can be learnt about selection from gene frequency distribution? | polymorphism has been studied at the esterase 6 locus in the yellow fever mosquito aedes aegypti (l.) in laboratory stocks. at least 12 alleles are present, with up to four coexisting in a stock. the allele frequency distribution is quite sharply peaked at a mode of about 0.25. the experimental data are compared with the results of simulation based on two models, one in which the initial global distribution is taken to be the stationary distribution obtained from the neutral model assuming m = 4 ... | 0 | 3792826 |
| transport of palmitic acid across the tegument of the entomophilic nematode romanomermis culicivorax. | romanomermis culicivorax juveniles, dissected out of aedes aegypti larvae 7 days after infection, were incubated under controlled conditions in isotonic saline containing (1)c-u-palmitic acid to investigate the nature of the transport mechanism(s) used by the nematode for transcuticular uptake of palmitic acid. net uptake of the isotope by the nematode was of a logarithmic nature with respect to time. uptake of palmitic acid was accomplished by a combination of diffusion and a mediated process w ... | 0 | 19295867 |
| effect of aedes aegypti (diptera:culicidae) age on sex ratios in romanomermis culicivorax (nematoda:mermithidae). | first, second, third, early and late fourth-instar larvae, and pupae of aedes aegypti were infected with romanomerrais culicivorax and reared at 20, 25, and 30 c. an increase in the ratio of male to female nematodes was observed with increase in host age at the time of infection at each temperature. the number of pupal and late fourth-instar infections was low, but r. culicivorax continued to develop in adult a. aegypti. since male nematodes were recovered from both male and female hosts infecte ... | 0 | 19295853 |
| glutathione biosynthesis in the aging adult yellow-fever mosquito [aedes aegypti (louisville)]. | our previous findings [hazelton & lang (1978) fed. proc. fed. am. soc. exp. biol. 37(6), 2378 (abstr.)] demonstrated a senescence-specific decrease in glutathione (gsh) concentration in the yellow-fever mosquito aedes aegypti (louisville)]. as a possible mechanism for this change, gsh biosynthesis was investigated in adult mosquitoes of different ages through the life-span. biosynthesis was measured as the incorporation rate of [14c]glycine or [14c]cystine into glutathione. essential information ... | 0 | 6860301 |
| glutathione s-transferase activities in the yellow-fever mosquito [aedes aegypti (louisville)] during growth and aging. | our previous findings [hazelton & lang (1978) fed. proc. fed. am. soc. exp. biol. 37(6), 2378 (abstr.)] demonstrated aging-specific changes in glutathione concentrations in the yellow-fever mosquito [aedes aegypti (louisville)]. a possible mechanism could be increased utilization via glutathione s-transferase. thus glutathione s-transferase activities were measured in mosquito samples from the entire life span, including growth, maturity and senescence. methods were validated for the quantitativ ... | 0 | 6860300 |
| uptake of lipids by the entomophilic nematode romanomermis culicivorax. | romanomermis culicivorax juveniles were dissected out of aedes aegypti larvae 7 days after infection and incubated under controlled conditions in isotonic saline containing a (1)c-labeled fatty acid (palmitic acid), monoacylglycerol (glycerol monoolein), or triacylglycerol (glycerol tripalmate) nutrient source. the mermithid absorbed each of these lipids from the incubation medium, the rate of uptake being greatest for glycerol monoolein. no lipase activity was detected in whole nematode homogen ... | 0 | 19295741 |
| role of a modified ovitrap in the control of aedes aegypti in houston, texas, usa. | a modified ovitrap from which larvae could not escape was employed for one year for the control of aedes aegypti at blossom heights, houston, texas. at the end of this period, the breteau index in the ovitrap area had declined by 36%, in contrast to a sharp increase of nearly 500% in the non-ovitrap area. the premises index in the ovitrap area remained unchanged, while the index in the non-ovitrap area increased by 440%. the problems associated with this control campaign and the use of these "au ... | 0 | 6980740 |
| effects of host diet on romanomermis culicivorax, a mermithid parasite of mosquitoes. | when larval mosquitoes (aedes aegypti) infected with the mermithid nematode romanomermis culicivorax were fed on a diet low in quantity or protein content or both, the number of postparasites which emerged from the hosts decreased and host mortality increased marginally. parasitic development was prolonged and became asynchronous in nutritionally deprived hosts. nematodes emerged from insects infected by more than one nematode before the remaining juveniles comprising such infections had complet ... | 0 | 19300764 |
| the biosynthesis of deoxyribonucleic acid during the life-span of the mosquito. | previous results from this laboratory [kao et al, (1976) biochem. j. 154, 471-480] demonstrated that a low-molecular-weight dna species, "sdna", present in high concentrations during rapid larval growth of the yellow-fever mosquito, aedes aegypti, may be an intermediate in dna replication. we have now determined the life-span profiles of synthetic rates and the steady-state contents of sdna and total dna by radiometric and biochemical procedures and by using mosquitoes grown and maintained under ... | 0 | 938460 |
| a deoxyribonucleic acid-replication intermediate in the growing mosquito. | in previous experiments on growth and aging in the yellow-fever mosquito, aedes aegypti, a low mol. wt. (500000) dna species was found in the supernatant fraction after ultracentrifugation of homogenates of rapidly-growing larvae. this dna species, "sdna", constituted 30-40% of total dna in 2-4-day-old larvae, but was less than 5% in older larvae, pupae and adults. we have now isolated and characterized sdna and initiated experiments to determine its metabolic role. isolated sdna has the same ph ... | 0 | 938459 |
| the ovary as a source of alpha-ecdysone in an adult mosquito. | the ovaries of the mosquito aedes aegypti cultured in vitro secrete material that behaves like ecdysone in a radioimmunoassay. the material was identified as alpha-ecdysone by high-resolution liquid and gas-liquid chromatography. secretion reached a maximum 16 hr after a blood meal as shown by bioassay and direct determination. ovariectomy reduced the concentration of ecdysone in the adult after a blood meal. qualitative analysis of whole-body extracts indicated beta-ecdysone to be the principal ... | 0 | 1059110 |
| diminution and enlargement of the mosquito rhabdom in light and darkness. | the rhabdoms of the larval ocelli of the mosquito aedes aegypti undergo morphological light and dark adaptation over periods of hours. the rhabdom enlarges during dark adaptation and grows smaller during light adaptation. diminution is exponential, enlargement linear, and rates of change are proportional to log light intensity. rhabdoms maintained at a constant intensity level off at a constant volume proportional to log intensity. we argue that changes in rhabdom volume after changes in light i ... | 0 | 1176940 |
| ecdysone-mediated stimulation of dopa decarboxylase activity and its relationship to ovarian development in aedes aegypti. | very little dopa decarboxylase activity is detectable in adult female mosquitoes aedes aegypti which have not been allowed to engorge blood. however, when such females are injected with the molting hormone beta-ecdysone a marked stimulation of this enzyme's activity is observable. no stimulation is observed in males similarly injected, nor in females injected with cholesterol or a juvenile hormone mimic. in addition, ecdysone injection initiates ovarian development in these anautogenous non-bloo ... | 0 | 4827909 |
| the control of aedes aegypti during the yellow fever epidemic in luanda, angola, in 1971. | vector control was carried out in three cycles with ulv technical malathion sprayed from aircraft at the application rate of 500 ml/ha. successive reductions of 84%, 93.6%, and 96% in the pretreatment density of a. aegypti were attained, a range of 77-98% being observed over a 24-day period. | 0 | 4543554 |
| spectral sensitivity of larval mosquito ocelli. | the spectral sensitivity of lateral ocelli in both wild-type and white-eyed larvae of the yellow fever mosquito aedes aegypti l. (reared in darkness) was measured by means of the electroretinogram. the spectral sensitivity is maximal at about 520 nm, with a small secondary peak near 370 nm. when allowance is made for some screening and filtering by the eye tissues, the spectral sensitivity is in reasonable agreement with the absorption spectrum of ocellar rhodopsin (lambda(max) = 515 nm). | 0 | 5029552 |
| rhodopsin of the larval mosquito. | larvae of the mosquito aedes aegypti have a cluster of four ocelli on each side of the head. the visual pigment of each ocellus of mosquitoes reared in darkness was characterized by microspectrophotometry, and found to be the same. larval mosquito rhodopsin (lambda(max) = 515 nm) upon short irradiation bleaches to a stable photoequilibrium with metarhodopsin (lambda(max) = 480 nm). on long irradiation of glutaraldehyde-fixed tissues or in the presence of potassium borohydride, bleaching goes fur ... | 0 | 5029551 |
| permeability of the ovarian follicle of aedes aegypti mosquitoes. | the passage of tracers of various molecular weights into resting and vitellogenic ovarian follicles of aedes aegypti mosquitoes was studied ultrastructurally. the outermost layer of the follicular sheath (the basement lamina) is a coarse mechanical filter. it is freely permeable to particles with molecular weights ranging from 12,000 to 500,000 (i.e. cytochrome c, peroxidase, hemoglobin, catalase, ferritin, immunoglobulin (igg)-peroxidase, iron dextran and thorotrast) that have dimensions less t ... | 0 | 4104968 |
| ultra-low-volume ground aerosols of technical malathion for the control of aedes aegypti l. | the efficacy of malathion aerosols applied from the ground was evaluated for the control of ae. aegypti. several techniques for applying the aerosols to an inhabited locality were investigated, and it was found that excellent control of adult mosquitos could be obtained with a dosage of 438 ml/ha. two treatments carried out 3 days apart enabled the adult mosquito population to be reduced by 99%, and it took about 2 weeks to regain its pretreatment level. schedules of treatment and strategies to ... | 0 | 5317014 |
| [aedes aegypti and potential vectors of yellow fever in the democratic republic of somalia and in the french territory of afars and issas]. | 0 | 5316916 | |
| [sensitivity of and resistance to insecticides of aedes aegypti in west africa and methods of control of the vector]. | 0 | 5316917 | |
| population control potential of heterozygous translocations as determined by computer simulations. | a possible method for genetic control of insect vector species involves the use of translocation heterozygotes. the potential of single and double heterozygotes already available in aedes aegypti has been investigated with computer simulations of release strategies. such simulations indicate a possible role for translocation heterozygotes of these types in an insect population characterized by a 5-fold population growth per generation, or less. | 0 | 5317450 |