Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
outsmarting olfaction: the next generation of mosquito repellents. 016002364
passive prophylaxis with permethrin-treated tents reduces mosquito bites among north american summer campers.over 2 million adolescents participate in summer-camp experiences, placing themselves at risk for mosquito-borne illness. insect repellent is recommended but often not used. it is unknown whether permethrin treatment of a location, such as a campsite, provides passive prophylaxis reducing mosquito bites among all persons in the immediate vicinity.015813141
effects of ingested vertebrate-derived factors on insect immune responses.during the process of blood feeding insect vectors are exposed to an array of vertebrate-derived blood factors ranging from byproducts of blood meal digestion to naturally occurring products in the blood including growth hormones, cytokines and factors derived from blood-borne pathogens themselves. in this review, we examine the ability of these ingested vertebrate blood factors to alter the innate pathogen defenses of insect vectors. the ability of these factors to modify the immune responses o ...025401083
high degree of single nucleotide polymorphisms in california culex pipiens (diptera: culicidae) sensu lato.resolution of systematic relationships among members of the culex pipiens (l.) complex has important implications for public health as well as for studies on the evolution of sibling species. currently held views contend that in california considerable genetic introgression occurs between cx. pipiens and cx. quinquefasciatus say, and as such, these taxa behave as if they are a single species. development of high throughput snp genotyping tools for the analysis of cx. pipiens complex population s ...022493847
no evolutionary response to four generations of laboratory selection on antipredator behavior of aedes albopictus: potential implications for biotic resistance to invasion.aedes albopictus (skuse) is an invasive container-dwelling mosquito and an important disease vector that co-occurs with the native mosquito, aedes triseriatus (say), and the predatory midge, corethrella appendiculata (grabham). larval ae. triseriatus show significantly greater antipredatory responses when compared to larval ae. albopictus in the presence of predation cues from c. appendiculata. the potential for evolution of antipredatory behavioral responses to c. appendiculata in ae. albopictu ...019645279
emerging and re-emerging viruses in the era of globalisation. 019657478
towards a hybrid agent-based model for mosquito borne disease.agent-based models (abm) are used to simulate the spread of infectious disease through a population. detailed human movement, demography, realistic business location networks, and in-host disease progression are available in existing abms, such as the epidemic simulation system (episims). these capabilities make possible the exploration of pharmaceutical and non-pharmaceutical mitigation strategies used to inform the public health community. there is a similar need for the spread of mosquito bor ...026618203
chikungunya virus as cause of febrile illness outbreak, chiapas, mexico, 2014.since chikungunya virus (chikv) was introduced into the americas in 2013, its geographic distribution has rapidly expanded. of 119 serum samples collected in 2014 from febrile patients in southern mexico, 79% were positive for chikv or igm against chikv. sequencing results confirmed chikv strains closely related to caribbean isolates.026488312
symbionts conferring resistance to viruses in insects. 025417905
false-negative dengue cases in roraima, brazil: an approach regarding the high number of negative results by ns1 ag kits.serum samples from 150 ns1-negative (platelia elisa) patients presumptively diagnosed with dengue were analyzed by the taqman probed real-time reverse transcription pcr (taqman qrt-pcr) method. the qrt-pcr positive samples were tested for serotype by semi-nested rt-pcr and a qualitative immunochromatographic assay for igg and igm. molecular detection methods showed 33 (22%) positive samples out of 150 ns1-antigen negative samples. of these, 72% were collected up to day 2 after the onset of sympt ...025229228
clinicohematological profiles of hospitalized patients with dengue in kolkata in 2012 epidemic, west bengal.dengue usually presents itself with subclinical or mild infection to full blown dengue fever (df) to dengue hemorrhagic fever (dhf) and dengue shock syndrome (dss). in kolkata, dengue started in 1824 followed by five epidemics that occurred in 1836, 1906, 1911, 1923 and 2005. the aim of this investigation is to study the clinicohematological correlation of all patients with respect to their gender that were admitted to "kali pada chowdhury medical college and hospital" during 2012 epidemic. amon ...025242847
assessing the risk of international spread of yellow fever virus: a mathematical analysis of an urban outbreak in asuncion, 2008.yellow fever virus (yfv), a mosquito-borne virus endemic to tropical africa and south america, is capable of causing large urban outbreaks of human disease. with the ease of international travel, urban outbreaks could lead to the rapid spread and subsequent transmission of yfv in distant locations. we designed a stochastic metapopulation model with spatiotemporally explicit transmissibility scenarios to simulate the global spread of yfv from a single urban outbreak by infected airline travelers. ...022302873
a case of yellow fever vaccine-associated viscerotropic disease in ecuador.we report the first case of viscerotropic syndrome in ecuador. because of similarities between yellow fever and viscerotropic syndrome, the incidence of this recently described complication of vaccination with the 17d yellow fever vaccine is not known. there is a large population in south america that is considered at risk for possible reemergence of urban yellow fever. knowledge of potentially fatal complications of yellow fever vaccine should temper decisions to vaccinate populations where the ...020348528
the deadly ebola threat in the midst of an overwhelming dengue epidemic.the recent death tolls and morbidities associated with two deadly viral haemorrhagic fevers (vhfs), i.e., ebola and dengue, are simply shocking. by the end of august 2014, 65 672 people were afflicted with dengue fever (df) in malaysia, with 9505 from kelantan, and there were 128 reported deaths. more astounding are the death tolls associated with ebola: 3091 deaths from 6574 reported cases so far. it is not difficult to imagine the potential disaster if ebola spreads beyond africa. vhfs are cha ...025897277
a three year retrospective study on the increasing trend in seroprevalence of dengue infection from southern odisha, india.in odisha, several cases of dengue virus infection were detected for the first time in 2010, the importance of dengue as a serious mosquito-borne viral infection was felt only in 2011 with the reporting of many more positive cases. this retrospective three year study was done to find out the seroprevalence of dengue ig m0 antibody and to know the predominant serotype of dengue virus among the patients suspected to have dengue virus infection in a tertiary care hospital in southern odisha, india.025579149
emerging arboviruses and public health challenges in brazil.environmental modification by anthropogenic actions, disordered urban growth, globalization of international exchange and climate change are some factors that help the emergence and dissemination of human infectious diseases transmitted by vectors. this review discusses the recent entry of three arboviruses in brazil: chikungunya, west nile, and zika virus, focusing on the challenges for the country's public health. the brazilian population is exposed to infections caused by these three arboviru ...027355468
climate and human health: the impact of climate change on vector-borne diseases, paphos, cyprus (17-19 october 2012). 024428826
microhabitat partitioning of aedes simpsoni (diptera: culicidae).yellow fever virus is a reemerging infection responsible for widespread, sporadic outbreaks across africa. although aedes aegypti (l.) is the most important vector globally, in east africa, epidemics may be vectored by aedes bromeliae (theobald), a member of the aedes simpsoni (theobald) species complex. the ae. simpsoni complex contains 10 subspecies, of which ae. bromeliae alone has been incriminated as a vector of yellow fever virus. however, morphological markers cannot distinguish ae. brome ...024897852
zika. an emerging teratogenic virus.[no abstract available].027464857
the global distribution of yellow fever and dengue.yellow fever has been subjected to partial control for decades, but there are signs that case numbers are now increasing globally, with the risk of local epidemic outbreaks. dengue case numbers have also increased dramatically during the past 40 years and different serotypes have invaded new geographical areas. despite the temporal changes in these closely related diseases, and their enormous public health impact, few attempts have been made to collect a comprehensive dataset of their spatial an ...016647971
evolutionary and ecological characterization of mayaro virus strains isolated during an outbreak, venezuela, 2010.in 2010, an outbreak of febrile illness with arthralgic manifestations was detected at la estación village, portuguesa state, venezuela. the etiologic agent was determined to be mayaro virus (mayv), a reemerging south american alphavirus. a total of 77 cases was reported and 19 were confirmed as seropositive. mayv was isolated from acute-phase serum samples from 6 symptomatic patients. we sequenced 27 complete genomes representing the full spectrum of mayv genetic diversity, which facilitated de ...026401714
phylogeography of dengue virus serotype 4, brazil, 2010-2011.dengue virus serotype 4 (denv-4) reemerged in roraima state, brazil, 28 years after it was last detected in the country in 1982. to study the origin and evolution of this reemergence, full-length sequences were obtained for 16 denv-4 isolates from northern (roraima, amazonas, pará states) and northeastern (bahia state) brazil during the 2010 and 2011 dengue virus seasons and for an isolate from the 1982 epidemic in roraima. spatiotemporal dynamics of denv-4 introductions in brazil were applied t ...023092706
co-circulation of dengue and chikungunya viruses, al hudaydah, yemen, 2012.we investigated 400 cases of dengue-like illness in persons hospitalized during an outbreak in al hudaydah, yemen, in 2012. overall, 116 dengue and 49 chikungunya cases were diagnosed. dengue virus type 2 was the predominant serotype. the co-circulation of these viruses indicates that mosquitoborne infections represent a public health threat in yemen.025061762
reply to skalsky et al.: a microrna-like small rna from dengue virus. 025061641
small bite, big threat: the burden of vector-borne diseases. 025909072
clinical applicability of various dengue diagnostic tests in resource-limited endemic settings.dengue is one of the most important arboviral infections caused by one of the four dengue serotypes, 1-4.025191051
zika virus infection after travel to tahiti, december 2013. 025062427
vertical transmission of dengue virus in aedes aegypti collected in puerto iguazú, misiones, argentina.a finding of vertical transmission of the den 3 virus in male specimens of aedes aegypti, collected in the 2009 fall-winter period, in puerto iguazú city, misiones, argentina, using the rt-pcr technique in a 15-specimen pool is reported. this result is analyzed within the context of the epidemiological situation of argentina's northeast border.024626420
mosquito larvicidal properties of mirabilis jalapa (nyctaginaceae) against anopheles stephensi, aedes aegypti & culex quinquefasciatus (diptera: culicidae). 025366214
updating the geographical distribution and frequency of aedes albopictus in brazil with remarks regarding its range in the americas.the geographical distribution of aedes albopictus in brazil was updated according to the data recorded across the country over the last eight years. countrywide house indexes (hi) for ae. albopictus in urban and suburban areas were described for the first time using a sample of brazilian municipalities. this mosquito is currently present in at least 59% of the brazilian municipalities and in 24 of the 27 federal units (i.e., 26 states and the federal district). in 34 brazilian municipalities, th ...025317707
imported dengue fever in tuscany, italy, in the period 2006 to 2012.this report focuses on epidemiological and clinical features of dengue fever (df) in tuscany (italy) between 2006 and 2012. sixty-one df cases were diagnosed, 32 of which were in the period of aedes albopictus activity. some clinical (arthralgia/myalgia, nausea/vomiting, and skin rash), laboratory (leukopenia and thrombocytopenia), and epidemiological characteristics (travel in a continent other than africa) significantly distinguished df cases from other febrile illnesses. our data stress the i ...025155927
molecular epidemiology and phylogenetic analysis of dengue virus type-1 and 2 isolated in malaysia.detection of different serotypes of dengue virus and provide information on origin, distribution and genotype of the virus.026150855
re-emergence of dengue virus serotype 2 strains in the 2013 outbreak in nepal.epidemiological interventions and mosquito control are the available measures for dengue control. the former approach uses serotype and genetic information on the circulating virus strains. dengue has been frequently reported from nepal, but this information is mostly lacking. the present study was done to generate a comprehensive clinical and virological picture of a dengue outbreak in nepal during 2013.026905233
reemergence and autochthonous transmission of dengue virus, eastern china, 2014.in 2014, 20 dengue cases were reported in the cities of wenzhou (5 cases) and wuhan (15 cases), china, where dengue has rarely been reported. dengue virus 1 was detected in 4 patients. although most of these cases were likely imported, epidemiologic analysis provided evidence for autochthonous transmission.026292098
molecular detection and typing of dengue viruses from archived tissues of fatal cases by rt-pcr and sequencing: diagnostic and epidemiologic implications.diagnosis of dengue virus (denv) infection in fatal cases is challenging because of the frequent unavailability of blood or fresh tissues. for formalin-fixed, paraffin-embedded (ffpe) tissues immunohistochemistry (ihc) can be used; however, it may not be as sensitive and serotyping is not possible. the application of reverse transcription-polymerase chain reaction (rt-pcr) for the detection of denv in ffpe tissues has been very limited. we evaluated ffpe autopsy tissues of 122 patients with susp ...022302871
deadly intracranial bleed in patients with dengue fever: a series of nine patients and review of literature.dengue fever is a global pandemic threat with increasing incidence. to date, there are no cures and the effectiveness of dengue vaccines is still uncertain. world heath organization introduced expanded dengue syndrome to include unusual presentations of dengue fever including severe neurologic complications. one of the deadly complications is intracranial hemorrhage (ich).027365962
urban mosquito fauna in mérida city, méxico: immatures collected from containers and storm-water drains/catch basins.we examined the species composition and temporal occurrence of immature mosquitoes in containers and storm-water drains/catch basins from november 2011 to june 2013 in mérida city, méxico. a wide range of urban settings were examined, including residential premises, vacant lots, parking lots, and streets or sidewalks with storm-water drains/catch basins. in total, 111,776 specimens of 15 species were recorded. the most commonly collected species were aedes (stegomyia) aegypti (l.) (n = 60,961) a ...025429168
dengue: challenges for policy makers and vaccine developers.because of the increasing incidence, geographic expansion and economic burden of dengue transmission, dengue poses major challenges to policy makers. a vaccine against dengue is urgently needed, but vaccine development has been hampered by the lack of an appropriate animal model, poor understanding of correlates of successful human immunity, the fear of immune enhancement, and viral interference in tetravalent combinations. the most suitable target epitopes for vaccines, as well as the role of n ...024781826
mayaro virus infection, amazon basin region, peru, 2010-2013.during 2010-2013, we recruited 16 persons with confirmed mayaro virus infection in the peruvian amazon to prospectively follow clinical symptoms and serologic response over a 12-month period. mayaro virus infection caused long-term arthralgia in more than half, similar to reports of other arthritogenic alphaviruses.024210165
aedes taeniorhynchus vectorial capacity informs a pre-emptive assessment of west nile virus establishment in galápagos.increased connectivity with the mainland has led to the arrival of many invasive species to the galápagos islands, including novel pathogens, threatening the archipelago's unique fauna. here we consider the potential role of the mosquito aedes taeniorhynchus in maintaining the flavivirus west nile virus [wnv] should it reach the islands. we report on three components of vectorial capacity - vector competency, distributional abundance and host-feeding. in contrast to usa strains, galápagos a. tae ...023519190
antiviral defense mechanisms in honey bees.honey bees are significant pollinators of agricultural crops and other important plant species. high annual losses of honey bee colonies in north america and in some parts of europe have profound ecological and economic implications. colony losses have been attributed to multiple factors including rna viruses, thus understanding bee antiviral defense mechanisms may result in the development of strategies that mitigate colony losses. honey bee antiviral defense mechanisms include rna-interference ...026273564
can horton hear the whos? the importance of scale in mosquito-borne disease.the epidemiology of vector-borne pathogens is determined by mechanisms and interactions at different scales of biological organization, from individual-level cellular processes to community interactions between species and with the environment. most research, however, focuses on one scale or level with little integration between scales or levels within scales. understanding the interactions between levels and how they influence our perception of vector-borne pathogens is critical. here two examp ...024724278
coi barcode versus morphological identification of culex (culex) (diptera: culicidae) species: a case study using samples from argentina and brazil.sequences of the cytochrome c oxidase subunit i (coi) mitochondrial gene from adults of 22 culex (culex) species from argentina and brazil were employed to assess species identification and to test the usefulness of coi for barcoding using the best close match (bcm) algorithm. a pairwise kimura two-parameter distance matrix including the mean intra and interspecific distances for 71 coi barcode sequences was constructed. of the 12 coi lineages recovered in the neighbour-joining topology, five co ...024473810
dengue vaccines: recent developments, ongoing challenges and current candidates.dengue is among the most prevalent and important arbovirus diseases of humans. to effectively control this rapidly spreading disease, control of the vector mosquito and a safe and efficacious vaccine are critical. despite considerable efforts, the development of a successful vaccine has remained elusive. multiple factors have complicated the creation of a successful vaccine, not the least of which are the complex, immune-mediated responses against four antigenically distinct serotypes necessitat ...023984962
the roles of mosquito and bird communities on the prevalence of west nile virus in urban wetland and residential habitats.this study investigated the impacts of urban wetlands and their adjacent residential environments on the transmission dynamics of west nile virus (wnv) within the state of new jersey (usa). a working hypothesis was that urban wetlands decrease the local prevalence of wnv through the dilution effect from increased bird diversity, and through relative reductions in the numbers of competent avian host and mosquito species commonly associated with wnv. surveys of mosquito and bird communities were u ...025484570
travel medicine for the extreme traveler. 017101310
larvicidal & ovicidal efficacy of pithecellobium dulce (roxb.) benth. (fabaceae) against anopheles stephensi liston & aedes aegypti linn. (diptera: culicidae).in view of the recently increased interest in developing plant origin insecticides as an alternative to chemical insecticide, this study was undertaken to assess the larvicidal and ovicidal potential of the crude hexane, benzene, chloroform, ethyl acetate and methanol solvent extracts from the medicinal plant pithecellobium dulce against the mosquito vectors, anopheles stephensi and aedes aegypti (diptera: culicidae).024056567
preliminary findings on bagaza virus (flavivirus: flaviviridae) growth kinetics, transmission potential & transovarial transmission in three species of mosquitoes.bagaza virus (bagv), a flavivirus synonymous with israel turkey meningoencephalitis virus, has been found to circulate in india. bagv has recently been held responsible for inducing febrile illness in humans and causing unusually high mortality to wild birds in spain. a study was therefore, undertaken to determine its replication kinetics in certain mosquitoes and to determine vector competence and potential of the mosquitoes to transmit bagv experimentally.024056604
zika virus: indian perspectives.the emergence of zika virus (ziv), a mosquito borne flavivirus like dengue (den) and chikungunya (chik), in brazil in 2014 and its spread to various countries have led to a global health emergency. aedes aegypti is the major vector for ziv. fast dissemination of this virus in different geographical areas posses a major threat especially to regions where the population lacks herd immunity against the ziv and there is abundance of aedes mosquitoes. in this review, we focus on current global scenar ...027487998
rodents and risk in the mekong delta of vietnam: seroprevalence of selected zoonotic viruses in rodents and humans.in the mekong delta in southern vietnam, rats are commonly traded in wet markets and sold live for food consumption. we investigated seroprevalence to selected groups of rodent-borne viruses among human populations with high levels of animal exposure and among co-located rodent populations. the indirect fluorescence antibody test (ifat) was used to determine seropositivity to representative reference strains of hantaviruses (dobrava virus [dobv], seoul virus [seov]), cowpox virus, arenaviruses ( ...025629782
evidence that implicit assumptions of 'no evolution' of disease vectors in changing environments can be violated on a rapid timescale.projected impacts of climate change on vector-borne disease dynamics must consider many variables relevant to hosts, vectors and pathogens, including how altered environmental characteristics might affect the spatial distributions of vector species. however, many predictive models for vector distributions consider their habitat requirements to be fixed over relevant time-scales, when they may actually be capable of rapid evolutionary change and even adaptation. we examine the genetic signature o ...025688024
assessment of arbovirus surveillance 13 years after introduction of west nile virus, united states.before 1999, the united states had no appropriated funding for arboviral surveillance, and many states conducted no such surveillance. after emergence of west nile virus (wnv), federal funding was distributed to state and selected local health departments to build wnv surveillance systems. the council of state and territorial epidemiologists conducted assessments of surveillance capacity of resulting systems in 2004 and in 2012; the assessment in 2012 was conducted after a 61% decrease in federa ...026079471
interspecific larval competition between aedes albopictus and aedes japonicus (diptera: culicidae) in northern virginia.aedes albopictus (skuse) and aedes japonicus (theobald) are two of the most recent and widespread invasive mosquito species to have become established in the united states. the two species co-occur in water-filled artificial containers, where crowding and limiting resources are likely to promote inter- or intraspecific larval competition. the performance of northern virginia populations of ae. japonicus and ae. albopictus competing as larvae under field conditions was evaluated. per capita rates ...018714861
the burden of dengue and chikungunya worldwide: implications for the southern united states and california.dengue virus (denv) spreads to humans through the bite of an infected aedes aegypti or aedes albopictus mosquito and is a growing public health threat to both industrialized and developing nations worldwide. outbreaks of autochthonous dengue in the united states occurred extensively in the past but over the past 3 decades have again taken place in florida, hawaii, and texas as well as in american samoa, guam, northern mariana islands, puerto rico, and the us virgin islands. as the aedes vectors ...025960096
health economics of dengue: a systematic literature review and expert panel's assessment.dengue vaccines are currently in development and policymakers need appropriate economic studies to determine their potential financial and public health impact. we searched five databases (pubmed, embase, lilac, econlit, and wholis) to identify health economics studies of dengue. forty-three manuscripts were identified that provided primary data: 32 report economic burden of dengue and nine are comparative economic analyses assessing various interventions. the remaining two were a willingness-to ...021363989
regulation of cell survival and death during flavivirus infections.flaviviruses, ss(+) rna viruses, include many of mankind's most important pathogens. their pathogenicity derives from their ability to infect many types of cells including neurons, to replicate, and eventually to kill the cells. flaviviruses can activate tumor necrosis factor α and both intrinsic (bax-mediated) and extrinsic pathways to apoptosis. thus they can use many approaches for activating these pathways. infection can lead to necrosis if viral load is extremely high or to other types of c ...024921001
serratia odorifera mediated enhancement in susceptibility of aedes aegypti for chikungunya virus.the susceptibility of the mosquito to the invading pathogen is predominantly dictated by the complex interactions between the mosquito midgut and the surface proteins of the invading pathogen. it is well documented that the midgut microbiota plays an important role in determining the susceptibility of the mosquito to the pathogen. in the present study, we investigated the influence of serratia odorifera, an endogenous cultivable midgut inhabitant of aedes aegypti on the chikungunya virus (chikv) ...025027087
larvicidal efficacy of ethiopian ethnomedicinal plant juniperus procera essential oil against afrotropical malaria vector anopheles arabiensis (diptera: culicidae).to screen the essential oil of juniperus procera (j. procera) (cupressaceae) for larvicidal activity against late third instar larvae of anopheles arabiensis (an. arabiensis) patton, the principle malaria vector in ethiopia.025183156
economic value of dengue vaccine in thailand.with several candidate dengue vaccines under development, this is an important time to help stakeholders (e.g., policy makers, scientists, clinicians, and manufacturers) better understand the potential economic value (cost-effectiveness) of a dengue vaccine, especially while vaccine characteristics and strategies might be readily altered. we developed a decision analytic markov simulation model to evaluate the potential health and economic value of administering a dengue vaccine to an individual ...021540387
neurological infections in the returning international traveler.clinicians may encounter international travelers returning with exotic infections, emerging infectious diseases, or resurgent old-world infections. many of these infectious diseases can affect the nervous system directly or indirectly. the contemporary neurologist should therefore be cognizant of the clinical manifestations, potential complications, and appropriate management of common travel-related infections. this chapter focuses on five important infections that affect the central nervous sy ...025147444
dengue antibody prevalence in german travelers.we studied 2,259 german citizens after they returned from dengue-endemic countries from 1996 to 2004. serotype-specific dengue antibodies indicated acute infections in 51 (4.7%) travelers with recent fever and 13 (1.1%) travelers with no recent fever, depending largely on destination and epidemic activity in the countries visited.015890135
the tortoise or the hare? impacts of within-host dynamics on transmission success of arthropod-borne viruses.arthropod-borne viruses (arboviruses) are maintained in a cycle of alternating transmission between vertebrate hosts and arthropod vectors. arboviruses possess rna genomes capable of rapid diversification and adaptation, and the between-host trade-offs inherent to host alternation impose well-documented constraints on arbovirus evolution. here, we investigate the less well-studied within-host trade-offs that shape arbovirus replication dynamics and transmission. arboviruses generally establish l ...026150665
outbreak of dengue virus serotype-2 (denv-2) of cambodian origin in manipur, india - association with meteorological factors.dengue is a major health problem in many parts of india and its neighbouring countries. dengue cases have not been reported from manipur, a northeastern state of india till 2007. but, the sudden outbreak of fever with febrile illness during 2007 and 2008, suspected to be dengue/dengue haemorrhagic fever was investigated to detect the causative agent. potential impact of climatic variables on dengue transmission has been documented and hence the association between climatic factors, entomological ...023168706
the new health threats of exotic and global travel. 023265199
mosquito biting activity on humans & detection of plasmodium falciparum infection in anopheles stephensi in goa, india.knowledge of the bionomics of mosquitoes, especially of disease vectors, is essential to plan appropriate vector avoidance and control strategies. information on biting activity of vectors during the night hours in different seasons is important for choosing personal protection measures. this study was carried out to find out the composition of mosquito fauna biting on humans and seasonal biting trends in goa, india.022382193
a cluster of dengue cases in american missionaries returning from haiti, 2010.dengue is an acute febrile illness caused by four mosquito-borne dengue viruses (denv-1 to -4) that are endemic throughout the tropics. after returning from a 1-week missionary trip to haiti in october of 2010, 5 of 28 (18%) travelers were hospitalized for dengue-like illness. all travelers were invited to submit serum specimens and complete questionnaires on pre-travel preparations, mosquito avoidance practices, and activities during travel. denv infection was confirmed in seven (25%) travelers ...022232444
the emergence of zika virus as a global health security threat: a review and a consensus statement of the indusem joint working group (jwg).the zika virus (zikv), first discovered in 1947, has emerged as a global public health threat over the last decade, with the accelerated geographic spread of the virus noted during the last 5 years. the world health organization (who) predicts that millions of cases of zikv are likely to occur in the americas during the next 12 months. these projections, in conjunction with suspected zika-associated increase in newborn microcephaly cases, prompted who to declare public health emergency of intern ...027013839
mass scale screening of common arboviral infections by an affordable, cost effective rt-pcr method.to develop a rapid, cost effective rt-pcr method for the mass scale diagnosis of such diseases at the viremia stage to find out the actual disease burden in that area.023569876
unsuspected dengue and acute febrile illness in rural and semi-urban southern sri lanka.dengue virus (denv), a globally emerging cause of undifferentiated fever, has been documented in the heavily urbanized western coast of sri lanka since the 1960s. new areas of sri lanka are now being affected, and the reported number and severity of cases have increased. to study emerging denv in southern sri lanka, we obtained epidemiologic and clinical data and acute- and convalescent-phase serum samples from patients >2 years old with febrile illness. we tested paired serum samples for denv i ...022304972
knowledge and use of personal protective measures against mosquito borne diseases in a resettlement colony of delhi.mosquito borne diseases (mbds) are major public health problem in india. state of delhi is endemic for dengue and other mbds. the increasing incidence of mbds in delhi in recent years warrants a pro-active approach for their prevention. knowledge and use of personal protective measures (ppms) presents an effective strategy for prevention and control of mbds.024761243
novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides.insect pests are responsible for human suffering and financial losses worldwide. new and environmentally safe insecticides are urgently needed to cope with these serious problems. resistance to current insecticides has resulted in a resurgence of insect pests, and growing concerns about insecticide toxicity to humans discourage the use of insecticides for pest control. the small market for insecticides has hampered insecticide development; however, advances in genomics and structural genomics of ...022280344
dengue virus infection: current concepts in immune mechanisms and lessons from murine models.dengue viruses (denv), a group of four serologically distinct but related flaviviruses, are responsible for one of the most important emerging viral diseases. this mosquito-borne disease has a great impact in tropical and subtropical areas of the world in terms of illness, mortality and economic costs, mainly due to the lack of approved vaccine or antiviral drugs. infections with one of the four serotypes of denv (denv-1-4) result in symptoms ranging from an acute, self-limiting febrile illness, ...024182427
neurological manifestations of zika virus infection.zika virus (zikv) is a flavivirus (flaviviridae family) transmitted mainly by aedes mosquitoes. the virus was restricted to the african continent until its spread to south-east asia in the 1980's, the micronesia in 2007, the french polynesia in 2013 and, more recently in the americas in 2015, where, up to date, the world health organization (who) has estimated about 3-4 million total cases of zikv infection. during outbreaks in the french polynesia and brazil in 2013 and 2015, respectively, nati ...027878100
zika virus: epidemiology, current phobia and preparedness for upcoming mass gatherings, with examples from world olympics and pilgrimage.to describe zika virus (zikv) epidemiology, current phobia, and the required preparedness for its prevention during the upcoming mass gathering (mg) events.027648063
dengue fever in travelers to the tropics, 1998 and 1999.dengue fever (df) has become common in western travelers to the tropics. to improve the basis for travel advice, risk factors and dengue manifestations were assessed in 107 swedish patients for whom df was diagnosed after return from travel in 1998 and 1999. patient data were compared with data on a sample of all swedish travelers to dengue-endemic countries in the same years. only three of the patients had received pretravel advice concerning df from their physicians. hemorrhagic manifestations ...012702223
classification of dengue illness based on readily available laboratory data.the aim of this study was to examine retrospective dengue-illness classification using only clinical laboratory data, without relying on x-ray, ultrasound, or percent hemoconcentration. we analyzed data from a study of children who presented with acute febrile illness to two hospitals in thailand. multivariable logistic regression models were used to distinguish: (1) dengue hemorrhagic fever (dhf) versus dengue fever (df), (2) dhf versus df + other febrile illness (ofi), (3) dengue versus ofi, a ...020889865
zika virus: a roar after years of whispering. 027168917
zika in america: the year in review.short on funds and with no therapeutics or vaccines in sight, u.s. health officials are scrambling to prepare for a protracted fight with zika virus and the mosquitoes that carry it. in this article, the author focuses on the arrival of zika in the u.s.027990081
attractive toxic sugar baits: control of mosquitoes with the low-risk active ingredient dinotefuran and potential impacts on nontarget organisms in morocco.we evaluated the efficacy of attractive toxic sugar baits (atsb) in the laboratory and field with the low-risk active ingredient dinotefuran against mosquito populations. preliminary laboratory assays indicated that dinotefuran in solution with the sugar baits was ingested and resulted in high mortality of female culex quinquefasciatus say and aedes aegypti linnaeus. field studies demonstrated >70% reduction of mosquito populations at 3 wk post-atsb application. nontarget feeding of seven insect ...024331613
delayed egg hatching of anopheles gambiae (diptera: culicidae) pending water agitation.mosquito eggs laid on water surfaces typically hatch spontaneously soon after the embryos within them become fully formed first-instar larvae. however, we have found that anopheles gambiae giles, an important vector of malaria in africa, exhibits delayed hatching until the water surface is agitated, a feature overlooked in most laboratory colonies. agitation within 24 h postoviposition, before embryonation was complete, failed to stimulate delayed postembryonic hatching of isolated eggs on the f ...024897850
use of the cdc autocidal gravid ovitrap to control and prevent outbreaks of aedes aegypti (diptera: culicidae).populations ofaedes aegypti (l.) can be managed through reductions in adult mosquito survival, number of offspring produced, or both. direct adult mortality can be caused by the use of space sprays or residual insecticides to mosquito resting sites, and with a variety of residual insecticide-impregnated surfaces that are being tested, such as curtains, covers for water-storage vessels, bednets, and ovitraps. the fertility ofae. aegypti populations can be reduced by the use of autocidal ovipositi ...024605464
an improved trap to capture adult container-inhabiting mosquitoes.although dengue viruses are thought to be transmitted by aedes aegypti in puerto rico, aedes mediovittatus, the caribbean tree hole mosquito, is also a potential vector. this species is native to the greater antilles and has been shown to be a competent vector of dengue viruses in the laboratory. consequently, it has been suggested that ae. mediovittatus could be acting as a secondary vector or virus reservoir. this study was part of an ongoing investigation into this, and it aimed to determine ...024551969
hunger-dependent and sex-specific antipredator behaviour of larvae of a size-dimorphic mosquito.1. modification of behaviors in the presence of predators or predation cues is widespread among animals. costs of a behavioral change in the presence of predators or predation cues depend on fitness effects of lost feeding opportunities and, especially when organisms are sexually dimorphic in size or timing of maturation, these costs are expected to differ between the sexes. 2. larval aedes triseriatus (say) (diptera: culicidae) were used to test the hypothesis that behavioral responses of the s ...025309025
vertebrate hosts of aedes aegypti and aedes mediovittatus (diptera: culicidae) in rural puerto rico.the distribution of aedes (stegomyia) aegypti (l.), the main vector of dengue viruses (denv) worldwide, overlaps with aedes (gymnometopa) mediovittatus (coquillett), the caribbean treehole mosquito, in urban, suburban, and rural areas. ae. mediovittatus is a competent vector of denv with high rates of vertical denv transmission in the laboratory. this study determined whether ae. mediovittatus feeds on humans and compared its feeding patterns with co-occurring ae. aegypti in two rural communitie ...022897052
monitoring resistance to bacillus thuringiensis subsp. israelensis in the field by performing bioassays with each cry toxin separately.bacillus thuringiensis subsp. israelensis (bti) is increasingly used worldwide for mosquito control and is the only larvicide used in the french rhône-alpes region since decades. the artificial selection of mosquitoes with field-persistent bti collected in breeding sites from this region led to a moderate level of resistance to bti, but to relatively high levels of resistance to individual bti cry toxins. based on this observation, we developed a bioassay procedure using each bti cry toxin separ ...024037105
population dynamics.this chapter reviews aspects of population dynamics that may be conceptually important for biological control of mosquitoes. density dependent population regulation among immature stages has important implications for biological control of mosquito populations, primarily because it can lead to compensatory or overcompensatory mortality due to additions of a biological control agent. this can result in control efforts leading to no change in the target population, or actual increases in the targe ...017853611
competitive displacement and reduction. 017853612
consequences of detritus type in an aquatic microsystem: effects on water quality, micro-organisms and performance of the dominant consumer.1. variation in detritus quality and quantity can have significant effects on aquatic invertebrate food webs. allochthonous inputs of detritus are the principal energy source for organisms in aquatic tree hole microsystems. we compared the effects of two major detritus types found in tree holes, senescent leaves (sugar maple and white oak) and invertebrate carcasses (dead adult fruit flies and crickets), on several water quality characteristics of laboratory microcosms as well as on mass, surviv ...017476312
precipitation and temperature effects on populations of aedes albopictus (diptera: culicidae): implications for range expansion.we investigated how temperature and precipitation regime encountered over the life cycle of aedes albopictus (skuse) affects populations. caged populations of a. albopictus were maintained at 22, 26, and 30 degrees c. cages were equipped with containers that served as sites for oviposition and larval development. all cages were assigned to one of three simulated precipitation regimes: (1) low fluctuation regime - water within the containers was allowed to evaporate to 90% of its maximum before b ...011580037
temperature effects on the dynamics of aedes albopictus (diptera: culicidae) populations in the laboratory.we investigated how constant temperatures of 22, 24, and 26 degrees c experienced across the full life cycle affected the dynamics of caged populations of aedes albopictus (skuse). all cages were equipped with plastic beakers that served as sites for oviposition and larval development. we measured the per capita daily mortality and emergence rates of the adults and size of adult females, and estimated the intrinsic rate of increase (r) and asymptotic density (k) for each caged population. popula ...011476335
human and animal dirofilariasis: the emergence of a zoonotic mosaic.dirofilariasis represents a zoonotic mosaic, which includes two main filarial species (dirofilaria immitis and d. repens) that have adapted to canine, feline, and human hosts with distinct biological and clinical implications. at the same time, both d. immitis and d. repens are themselves hosts to symbiotic bacteria of the genus wolbachia, the study of which has resulted in a profound shift in the understanding of filarial biology, the mechanisms of the pathologies that they produce in their hos ...022763636
stable isotope analysis reveals detrital resource base sources of the tree hole mosquito, aedes triseriatus.1. detritus that forms the basis for mosquito production in tree hole ecosystems can vary in type and timing of input. we investigated the contributions of plant- and animal-derived detritus to the biomass of aedes triseriatus (say) pupae and adults by using stable isotope ((15)n and (13)c) techniques in lab experiments and field collections.2. lab-reared mosquito isotope values reflected their detrital resource base, providing a clear distinction between mosquitoes reared on plant or animal det ...021132121
senescent leaf exudate increases mosquito survival and microbial activity.we conducted experiments to evaluate the effects of soluble components in senescent leaf material on the growth and development of the eastern tree hole mosquito, aedes triseriatus (say). oak leaves that were either leached for three days to remove the labile nutrient fraction, or were not leached, served as basal nutrient inputs in each experiment.mosquito performance in microcosms containing leachate only was significantly worse compared with microcosms containing leaf material in combination ...021113430
interpopulation divergence in competitive interactions of the mosquito aedes albopictus.geographic variation in species interactions can have major effects on distributions. effects of such variation can be particularly evident for invasive species, in which variation in competitive ability can influence invasive success and impacts. we tested the hypothesis that coexistence or exclusion of the resident mosquito aedes aegypti results from variation among local populations of the invasive aedes albopictus in competitive interactions with a. aegypti. we also examined the role of vari ...019769119
leaf species identity and combination affect performance and oviposition choice of two container mosquito species.1. resource diversity can be an important determinant of individual and population performance in insects. fallen parts of plants form the nutritive base for many aquatic systems, including mosquito habitats, but the effect of plant diversity on mosquito production is poorly understood.2. to determine the effects of diverse plant inputs on larval mosquitoes, experiments were conducted that examined how leaves of vitis aestivalis, quercus virginiana, psychotria nervosa, and nephrolepis exalta aff ...020161198
digital image analysis to estimate numbers of aedes eggs oviposited in containers.monitoring reproductive rates in experiments involving aedine mosquitoes is tedious and time demanding. here, we demonstrate a protocol for rapid estimation of aedine mosquito egg number. the protocol uses imagej, a publicly available image analysis program developed at the u.s. national institutes of health. the method relies upon the oviposition behavior of aedes (i.e., ovipositing on a moist substrate instead of water surface) and upon the contrast between dark-colored aedine eggs and a light ...019181055
sex ratios of mosquitoes from long-term censuses of florida tree holes.pupal sexes of the most common mosquito species were determined in the course of biweekly censuses (with replacement) of the contents of 3-7 tree holes from 1980-2003 in vero beach, fl. a significant (p < 0.001) male bias was detected over this period for the most abundant species, aedes triseriatus. no significant deviation from a 1:1 sex ratio was detected among pupae of toxorhynchites rutilus or ae. albopictus, the latter species occurring in this community only since 1991. although pupae of ...018437808
characterisation of culex quinquefasciatus (diptera: culicidae) larval habitats at ground level and temporal fluctuations of larval abundance in córdoba, argentina.the aims of this study were to characterise the ground-level larval habitats of the mosquito culex quinquefasciatus, to determine the relationships between habitat characteristics and larval abundance and to examine seasonal larval-stage variations in córdoba city. every two weeks for two years, 15 larval habitats (natural and artificial water bodies, including shallow wells, drains, retention ponds, canals and ditches) were visited and sampled for larval mosquitoes. data regarding the water dep ...024037200
tackling the malaria problem in the south-east asia region: need for a change in policy?malaria is largely neglected in the south-east asia region (sear), although it has the highest number of people susceptible to the disease. malaria in the sear exhibits special epidemiological characteristics such as "forest malaria" and malaria due to migration across international borders. the greater mekong subregion (gms) has been a focal-point for the emergence of drug resistant malaria. with the recent emergence of artemisinin resistance, coupled with the limited availability of insecticid ...023481050
effects of intraspecific larval competition on adult longevity in the mosquitoes aedes aegypti and aedes albopictus.larval competition is common in container-breeding mosquitoes. the impact of competition on larval growth has been thoroughly examined and findings that larval competition can lead to density-dependent effects on adult body size have been documented. the effects of larval competition on adult longevity have been less well explored. the effects of intraspecific larval densities on the longevity of adults maintained under relatively harsh environmental conditions were tested in the laboratory by m ...019239615
Displaying items 14401 - 14500 of 14974