Publications

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[monthly report on the campaign of eradication of aedes aegypti in american countries, september, 1952]. 195313041772
the growth stimulating effect of apf, terramycin hydrochloride, vitamin b12 and an undetermined factor x upon aedes aegypti (l) diptera, culicidae. 195313007931
control of malaria in mauritius; eradication of anopheles funestus and aedes aegypti. 195313077717
studies on the intake of microfilariae by their insect vectors, their survival, and their effect on the survival of their vectors. i. dirofilaria immitis and aëdes aegypti. 195313080982
studies on plasmodium gallinaceum. iv. a comparison of the susceptibility of aedes aegypti, anopheles quadrimaculatus and anopheles freeborni. 195214933391
the mechanism of the transmission of myxomatosis in the european rabbit (oryctolagus cuniculus) by the mosquito aedes aegypti. 195214934625
studies on plasmodium gallinaceum. i. characteristics of the infection in the mosquito, aedes aegypti. 195114846794
[eradication of aedes aegypti and control of yellow fever; four year continental program]. 195114886443
[results of ddt application in french guiana; destruction of the aedes aegypti and spectabular reduction of malaria]. 195124541063
[innocuousness of the addition of 1 ppm of ddt to drinking water for the eradication of aedes aegypti]. 195114821037
estimation of traces of ddt using aedes aegypti larvae as a biological indicator. 195114817816
some nutritional requirements of adult mosquitoes (aedes aegypti) for oviposition. 195114851026
[attempt at control of aedes aegypti by application of ddt in water tanks]. 195014783641
[control of aedes aegypti in chile]. 195015411454
a method of infecting aedes aegypti with plasmodium gallinaceum from chick embryos. 195014795205
arrest of development of plasmodium gallinaceum in mosquitoes (aedes aegypti) by radiation effect of p32 1,2. 195015424666
relative susceptibility of aëdes aegypti, aëdes albopictus, aëdes canadensis and anopheles quadrimaculatus to plasmodium gallinaceum. 194918137143
aedes aegypti and other mosquito control measures in port sudan. 194915408260
rearing of anopheles quadrimaculatus say and aedes aegypti (l.) in the laboratory. 194915406584
bioassay systems for the pyrethrins; water-base sprays against aëdes aegypti l. and other flying insects. 194918151949
experiments in crossing aedes (stegomyia) aegypti linnaeus and aedes (stegomyia) albopictus skuse. 194917800955
toxicity of limewash containing ddt or gammexane to mosquitos, aëdes aegypti, l. 194818865550
extermination of aëdes aegypti in khartoum. 194818900760
the nutrition of the larva of aëdes aegypti linnaeus; protein and amino-acid requirements. 194818122654
the nutrition of the larva of aëdes aegypti linnaeus; lipid requirements. 194818105885
the nutrition of the larva of aëdes aegypti linnaeus. 4. protein and amino-acid requirements. 194816748417
the nutrition of the larva of aëdes aegypti linnaeus. 3. lipid requirements. 194816748416
stimuli involved in the attraction of aedes aegypti, l., to man. 194818104364
the effect of artificial blood meals containing the hydroxynaphthoquinone m2279 on the developmental cycle pf plasmodium gallinaceum in aedes aegypti. 194818864109
the effect of one plant extract and of certain drugs on the development of plasmodium gallinaceum in aedes aegypti. 194818867818
studies on cyclic passage of yellow fever virus in south american mammals and mosquitoes; marsupials (metachirus nudicaudatus and marmosa) in combination with aedes aegypti as vector. 194818898700
mortality of aedes aegypti feeding on rabbits receiving oral gammexane. 194720344387
practical laboratory methods for quantity rearing and handling of aedes aegypti mosquitoes to be infected with plasmodium gallinaceum. 194720266394
physiological factors which influence the infection of aedes aegypti with plasmodium gallinaceum. 194720279328
failure of aedes aegypti and culex pipiens to transmit plasmodium vaughani. 194720294091
observations on the effect of microclimate on biting by aëdes aegypti (l.) (dipt., culicid.). 194718920748
aedes aegypti control in the absence of a piped potable water supply. 194718897110
further observations on the nutritional requirements of the larva of aedes aegypti l. 194720269871
ddt and aedes aegypti control in british guiana. 194720264247
the inhibition of growth of larvae of aedes aegypti by certain anti-malarial drugs. 194720265407
winter survival of aedes aegypti in houston, texas. 194620995756
chlorine as a possible ovicide for aedes aegypti eggs. 194621027331
experiments upon the feeding of aedes aegypti through animal membranes with a view to applying this method to the chemotherapy of malaria. 194621014255
studies on cyclic passage of yellow fever virus in south american mammals and mosquitoes; marmosets (callithrix penicillata and leontocebus chrysomelas) in combination with aedes aegypti. 194620996629
occurrence of aedes aegypti in british guiana. 194520998212
aedes aegypti linnaeus, the yellow fever mosquito, in central missouri. 194217752151
measures instituted for the control of aëdes aegypti. 194018015233
the absence from the urine of pernicious anemia patients of a mosquito growth factor present in normal urine.extracts prepared from the urine of normal persons or patients with aplastic anemia or leukemia contain a substance, possibly flavine or a flavine compound, which under suitable conditions of test enhances the growth of larvae of the mosquito, aëdes aegypti. this substance is lacking, or is present in much smaller amount, in extracts from the urine of pernicious anemia patients showing symptoms of the disease. extracts from the urine of the same patients after adequate treatment contain as much ...193819870733
control of stegomyia fasciata (ædes ægypti) mosquitoes in indian country craft by a mosquito-proof metal cap (bennett pattern) for drinking-water receptacles. 193829014217
the multiplication of the virus of yellow fever in aedes aegypti.aëdes aegypti have been shown to be capable of multiplying the asibi strain of yellow fever virus in their bodies. following the ingestion of infected blood, the content of virus falls for several days, reaching a minimum during the 1st week. it then increases rapidly until quantities of virus greater than those previously encountered can be demonstrated. the actual final amount of virus demonstrable, however, is subject to variations of which we know little.193719870651
a practical way of dealing with ædes ægypti (stegomyia fasciata) mosquito breeding in country craft. 193629013069
a practical way of dealing with ædes ægypti (stegomyia fasciata) mosquito breeding in country craft. 193629012997
the transmission of equine encephalomyelitis virus by aedes aegypti.in confirming kelser's work on the transmission of equine encephalomyelitis of the western type by aëdes aegypti it has been learned that the mosquitoes must be fed virus of high titer if positive results are to be secured. a period of from 4 to 5 days after feeding either on infected guinea pigs or on brain containing virus must elapse before the disease is transmitted by biting, but after this time transmission regularly results for a period of about 2 months. by inoculation, virus can be demo ...193519870442
recent laboratory contributions to the control of yellow fever: (section of tropical diseases and parasitology).the most important recent laboratory contributions to the control of yellow fever will be briefly summarized under three headings: (1) methods of diagnosis, (2) transmission, and (3) protection.(1) methods of diagnosis.-the development of improved methods of identification, in particular by immunity tests, has made it possible to diagnose yellow fever with much greater certainty. moreover, since the immunity following an attack of the disease is usually of life-long duration, it is possible to d ...193319989606
possibility of hereditary transmission of yellow fever virus by aedes aegypti (linn.).attempts to obtain passage of yellow fever virus from one generation to the next in a. aegypti were unsuccessful. subcutaneous injections at varying intervals of a saline emulsion of 200 eggs laid by an infective lot of mosquitoes produced no reaction in six normal m. rhesus monkeys. negative results were also obtained in five biting and two injection experiments with progeny of the same infective lot of mosquitoes in which seven normal monkeys were used. the eggs consisted of batches laid after ...192919869656
the filtrability of yellow fever virus as existing in the mosquito.the virus of yellow fever as it exists in aëdes aegypti mosquitoes, both in their so-called infective stage and in the intermediate condition termed the "incubation period", is capable of passing through berkefeld n filters when suspended in normal monkey serum, although earlier investigators have shown that the virus from infective mosquitoes will not do so when suspended in physiological salt solution. the virus of yellow fever as it exists in mosquitoes behaves with regard to filtration throu ...192919869658
studies on yellow fever in south america : iv. transmission experiments with aedes aegypti.1. batches of aëdes (stegomyia) aegypti which had fed on monkeys in the early febrile stage of yellow fever and which has subsequently passed the usually accepted extrinsic incubation period for the virus, failed to transmit the disease to normal monkeys in approximately fifty per cent of the experiments. during the same time over eighty per cent of blood transfers were successful. 2. the monkeys which failed to show fever following mosquito bites later proved resistant to the inoculation of blo ...192919869665
the incubation period of yellow fever in the mosquito.1. the yellow fever virus was found in infectious form in aedes aegypti throughout the entire period of the extrinsic incubation, as demonstrated by the injection of the bodies of mosquitoes into normal rhesus monkeys at daily intervals after the insects had fed on an infected animal. 2. the virus was transmitted through the bite of the mosquitoes, in one experiment on and after the 9th day, and in two experiments on the 12th day after the initial infecting feed. 3. the pathologic changes produc ...192819869467
the yellow-fever mosquito. 190617737726
concerning the geographic distribution of the yellow fever mosquito. 190319601151
toxicological effects of sphaeranthus indicus linn. (asteraceae) leaf essential oil against human disease vectors, culex quinquefasciatus say and aedes aegypti linn., and impacts on a beneficial mosquito predator.use of environmentally friendly, decomposable natural products for effective vector control has gained considerable momentum in modern society. in this study, essential oil of sphaeranthus indicus (si-eo) was extracted and further phytochemical screening revealed fourteen compounds with prominent peak area percentage of 24.9 and 22.54% in 3,5-di-tert-butyl-4-hydroxybenzaldehyde and benzene,2-(1,1-dimethylethyl)-1,4-dimethoxy, respectively. the si-eo was further evaluated for their larvicidal res ...028455566
larval food quantity affects the capacity of adult mosquitoes to transmit human malaria.adult traits of holometabolous insects are shaped by conditions experienced during larval development, which might impact interactions between adult insect hosts and parasites. however, the ecology of larval insects that vector disease remains poorly understood. here, we used anopheles stephensi mosquitoes and the human malaria parasite plasmodium falciparum, to investigate whether larval conditions affect the capacity of adult mosquitoes to transmit malaria. we reared larvae in two groups; one ...027412284
mechanisms of arthropod transmission of plant and animal viruses.a majority of the plant-infecting viruses and many of the animal-infecting viruses are dependent upon arthropod vectors for transmission between hosts and/or as alternative hosts. the viruses have evolved specific associations with their vectors, and we are beginning to understand the underlying mechanisms that regulate the virus transmission process. a majority of plant viruses are carried on the cuticle lining of a vector's mouthparts or foregut. this initially appeared to be simple mechanical ...010066833
transcriptional pausing controls a rapid antiviral innate immune response in drosophila.innate immune responses are characterized by precise gene expression whereby gene subsets are temporally induced to limit infection, although the mechanisms involved are incompletely understood. we show that antiviral immunity in drosophila requires the transcriptional pausing pathway, including negative elongation factor (nelf) that pauses rna polymerase ii (pol ii) and positive elongation factor b (p-tefb), which releases paused pol ii to produce full-length transcripts. we identify a set of g ...023084920
the status of infectious disease in the amazon region.the amazon river basin region is a vast territory with an area >7 million km2, encompassing parts of 9 south american countries: bolivia, brazil, colombia, ecuador, french guiana, guyana, peru, suriname, and venezuela. the amazon river, the longest river in the world, traverses the region from west to east, fed by multiple tributaries. the region also contains the largest tropical rainforest in the world, situated on a massive plain whose altitude is near sea level. with a climate characterized ...019331757
assessing the epidemic potential of rna and dna viruses.many new and emerging rna and dna viruses are zoonotic or have zoonotic origins in an animal reservoir that is usually mammalian and sometimes avian. not all zoonotic viruses are transmissible (directly or by an arthropod vector) between human hosts. virus genome sequence data provide the best evidence of transmission. of human transmissible virus, 37 species have so far been restricted to self-limiting outbreaks. these viruses are priorities for surveillance because relatively minor changes in ...027869592
molecular modeling and docking study to elucidate novel chikungunya virus nsp2 protease inhibitors.chikungunya is one of the tropical viral infections that severely affect the asian and african countries. absence of any suitable drugs or vaccines against chikungunya virus till date makes it essential to identify and develop novel leads for the same. recently, nsp2 cysteine protease has been classified as a crucial drug target to combat infections caused by alphaviruses including chikungunya virus due to its involvement viral replication. here in, we investigated the structural aspects of the ...026664062
novel genetic and molecular tools for the investigation and control of dengue virus transmission by mosquitoes.aedes aegypti is the principal vector of dengue virus (denv) throughout the tropical world. this anthropophilic mosquito species needs to be persistently infected with denv before it can transmit the virus through its saliva to a new vertebrate host. in the mosquito, denv is confronted with several innate immune pathways, among which rna interference is considered the most important. the ae. aegypti genome project opened the doors for advanced molecular studies on pathogen-vector interactions in ...024693489
microbiota-dependent priming of antiviral intestinal immunity in drosophila.enteric pathogens must overcome intestinal defenses to establish infection. in drosophila, the erk signaling pathway inhibits enteric virus infection. the intestinal microflora also impacts immunity but its role in enteric viral infection is unknown. here we show that two signals are required to activate antiviral erk signaling in the intestinal epithelium. one signal depends on recognition of peptidoglycan from the microbiota, particularly from the commensal acetobacter pomorum, which primes th ...026567510
rna interference-mediated antiviral defense in insects.small interfering rna (sirna)-mediated rna interference (rnai) pathways are critical for the detection and inhibition of rna virus replication in insects. recent work has also implicated rnai pathways in the establishment of persistent virus infections and in the control of dna virus replication. accumulating evidence suggests that diverse double-stranded rnas produced by rna and dna viruses can trigger rnai responses yet many viruses have evolved mechanisms to inhibit rnai defenses. therefore, ...026034705
mosquito immune responses to arbovirus infections.the principal mosquito innate immune response to virus infections, rna interference (rnai), differs substantially from the immune response to bacterial and fungal infections. the exo-sirna pathway constitutes the major anti-arboviral rnai response and its essential genetic components have been identified. recent research has also implicated the piwi-interacting rna pathway in mosquito anti-arboviral immunity, but piwi gene-family components involved are not well-defined. arboviruses must evade o ...025401084
host inflammatory response to mosquito bites enhances the severity of arbovirus infection.aedes aegypti mosquitoes are responsible for transmitting many medically important viruses such as those that cause zika and dengue. the inoculation of viruses into mosquito bite sites is an important and common stage of all mosquito-borne virus infections. we show, using semliki forest virus and bunyamwera virus, that these viruses use this inflammatory niche to aid their replication and dissemination in vivo. mosquito bites were characterized by an edema that retained virus at the inoculation ...027332734
factors shaping the adaptive landscape for arboviruses: implications for the emergence of disease.many examples of the emergence or re-emergence of infectious diseases involve the adaptation of zoonotic viruses to new amplification hosts or to humans themselves. these include several instances of simple mutational adaptations, often to hosts closely related to the natural reservoirs. however, based on theoretical grounds, arthropod-borne viruses, or arboviruses, may face several challenges for adaptation to new hosts. here, we review recent findings regarding adaptive evolution of arboviruse ...023374123
chikungunya virus and prospects for a vaccine.in 2004, chikungunya virus (chikv) re-emerged from east africa to cause devastating epidemics of debilitating and often chronic arthralgia that have affected millions of people in the indian ocean basin and asia. more limited epidemics initiated by travelers subsequently occurred in italy and france, as well as human cases exported to most regions of the world, including the americas where chikv could become endemic. because chikv circulates during epidemics in an urban mosquito-human cycle, con ...023151166
innate antiviral immunity in drosophila.the study of drosophila, and other genetically tractable insects, has expanded our understanding of innate immunity and more recently antiviral innate mechanisms. the drosophila antiviral program includes inflammatory signaling cascades as well as antiviral rna silencing and autophagy. this review will highlight the recent discoveries in antiviral immunity in insects and will reveal some of the lessons learned.020137906
tackling the most difficult diseases. genetics and genomics open new strategies to fight vector-borne diseases. 011600446
wing shape as an indicator of larval rearing conditions for aedes albopictus and aedes aegypti (diptera: culicidae).estimating a mosquito's vector competence, or likelihood of transmitting disease, if it takes an infectious bloodmeal, is an important aspect of predicting when and where outbreaks of infectious diseases will occur. vector competence can be affected by rearing temperature and inter- and intraspecific competition experienced by the individual mosquito during its larval development. this research investigates whether a new morphological indicator of larval rearing conditions, wing shape, can be us ...022897054
specificity of resistance to dengue virus isolates is associated with genotypes of the mosquito antiviral gene dicer-2.in contrast to the prevailing view that invertebrate immunity relies on broad-spectrum recognition and effector mechanisms, intrinsic genetic compatibility between invertebrate hosts and their pathogens is often highly specific in nature. solving this puzzle requires a better understanding of the molecular basis underlying observed patterns of invertebrate host-pathogen genetic specificity, broadly referred to as genotype-by-genotype interactions. here, we identify an invertebrate immune gene in ...023193131
a genome-wide rnai screen reveals that mrna decapping restricts bunyaviral replication by limiting the pools of dcp2-accessible targets for cap-snatching.bunyaviruses are an emerging group of medically important viruses, many of which are transmitted from insects to mammals. to identify host factors that impact infection, we performed a genome-wide rnai screen in drosophila and identified 131 genes that impacted infection of the mosquito-transmitted bunyavirus rift valley fever virus (rvfv). dcp2, the catalytic component of the mrna decapping machinery, and two decapping activators, ddx6 and lsm7, were antiviral against disparate bunyaviruses in ...023824541
rna interference in infectious tropical diseases.introduction of double-stranded rna (dsrna) into some cells or organisms results in degradation of its homologous mrna, a process called rna interference (rnai). the dsrnas are processed into short interfering rnas (sirnas) that subsequently bind to the rna-induced silencing complex (risc), causing degradation of target mrnas. because of this sequence-specific ability to silence target genes, rnai has been extensively used to study gene functions and has the potential to control disease pathogen ...018344671
transgene-mediated suppression of the rna interference pathway in aedes aegypti interferes with gene silencing and enhances sindbis virus and dengue virus type 2 replication.rna interference (rnai) is the major innate antiviral pathway in aedes aegypti that responds to replicating arboviruses such as dengue virus (denv) and sindbis virus (sinv). on the one hand, the mosquito's rnai machinery is capable of completely eliminating denv2 from ae. aegypti. on the other, transient silencing of key genes of the rnai pathway increases replication of sinv and denv2, allowing the viruses to temporally overcome dose-dependent midgut infection and midgut escape barriers (meb) m ...023331493
biological transmission of arboviruses: reexamination of and new insights into components, mechanisms, and unique traits as well as their evolutionary trends.among animal viruses, arboviruses are unique in that they depend on arthropod vectors for transmission. field research and laboratory investigations related to the three components of this unique mode of transmission, virus, vector, and vertebrate host, have produced an enormous amount of valuable information that may be found in numerous publications. however, despite many reviews on specific viruses, diseases, or interests, a systematic approach to organizing the available information on all f ...016223950
emerging and re-emerging viruses: a global challenge illustrated by chikungunya virus outbreaks.in recent decades, the issue of emerging and re-emerging infectious diseases, especially those related to viruses, has become an increasingly important area of concern in public health. it is of significance to anticipate future epidemics by accumulating knowledge through appropriate research and by monitoring their emergence using indicators from different sources. the objective is to alert and respond effectively in order to reduce the adverse impact on the general populations. most of the eme ...024175207
the role of environmental variables on aedes albopictus biology and chikungunya epidemiology.aedes albopictus is a vector of dengue and chikungunya viruses in the field, along with around 24 additional arboviruses under laboratory conditions. as an invasive mosquito species, ae. albopictus has been expanding in geographical range over the past 20 years, although the poleward extent of mosquito populations is limited by winter temperatures. nonetheless, population densities depend on environmental conditions and since global climate change projections indicate increasing temperatures and ...023916332
protective and pathogenic responses to chikungunya virus infection.chikungunya virus (chikv) is an arbovirus responsible for causing epidemic outbreaks of human disease characterized by painful and often debilitating arthralgia. recently chikv has moved into the caribbean and the americas resulting in massive outbreaks in naïve human populations. given the importance of chikv as an emerging disease, a significant amount of effort has gone into interpreting the virus-host interactions that contribute to protection or virus-induced pathology following chikv infec ...026366337
larval feeding behavior of three co-occurring species of container mosquitoes.interspecific differences in foraging behavior may help to determine whether the outcome of interspecific competition is coexistence or exclusion. mosquitoes in the genus culex are commonly described as foraging primarily by filtering the water column. this behavior contrasts with that of other container-dwelling genera, such as aedes and ochlerotatus, that are thought to forage primarily by browsing on container and detritus surfaces. we compared the feeding behavior of cx. pipiens, ae. albopic ...015707290
identification of mosquito avian-derived blood meals by polymerase chain reaction-heteroduplex analysis.a polymerase chain reaction (pcr) heteroduplex assay (hda) was developed to identify avian derived mosquito blood meals to the species level. the assay used primers amplifying a fragment of the cytochrome b gene from vertebrate but not invertebrate species. in culex tarsalis fed on quail, pcr products derived from the quail cytochrome b gene were detected seven days post-engorgement. in an analysis of wild-caught mosquitoes, 85% of blood-fed mosquitoes produced detectable pcr products. heterodup ...012201598
risk of transmission of viral haemorrhagic fevers and the insecticide susceptibilitystatus of aedes aegypti (linnaeus) in some sites in accra, ghana.dengue is one of the emerging diseases that can mostly only be controlled by vector control since there is no vaccine for the disease. although, dengue has not been reported in ghana, movement of people from neighbouring countries where the disease has been reported can facilitate transmission of the disease.027752187
barriers to success: how baculoviruses establish efficient systemic infections.the mechanisms used by baculoviruses to exit the midgut and cause systemic infection of their insect hosts have been debated for decades. after being ingested, baculoviruses reach the midgut, where several host barriers need to be overcome in order to establish successful infection. one of these barriers is the basal lamina, a presumably virus-impermeable extracellular layer secreted by the epithelial cells lining the midgut and trachea. this review discusses new evidence that demonstrates how t ...021300392
climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission.arguably one of the most important effects of climate change is the potential impact on human health. while this is likely to take many forms, the implications for future transmission of vector-borne diseases (vbds), given their ongoing contribution to global disease burden, are both extremely important and highly uncertain. in part, this is owing not only to data limitations and methodological challenges when integrating climate-driven vbd models and climate change projections, but also, perhap ...025688012
arbovirus infections.arbovirus (arthropod-borne virus) infections are increasingly important causes of neurologic disease in the united states through both endemic transmission and travel-associated infections. this article reviews the major arbovirus infections that can cause neurologic disease likely to be encountered in the united states.026633778
chikungunya vaccines in development.chikungunya virus has become a global health threat, spreading to the industrial world of europe and the americas; no treatment or prophylactic vaccine is available. since the late 1960s much effort has been put into the development of a vaccine, and several heterogeneous strategies have already been explored. only two candidates have recently qualified to enter clinical phase ii trials, a chikungunya virus-like particle-based vaccine and a recombinant live attenuated measles virus-vectored vacc ...026554522
south-to-north, cross-disciplinary training in global health practice: ten years of lessons learned from an infectious disease field course in jamaica.global commerce, travel, and emerging and resurging infectious diseases have increased awareness of global health threats and opportunities for collaborative and service learning. we review course materials, knowledge archives, data management archives, and student evaluations for the first 10 years of an intensive summer field course in infectious disease epidemiology and surveillance offered in jamaica. we have trained 300 students from 28 countries through collaboration between the university ...021896794
tagetes erecta linn. and its mosquitocidal potency against culex quinquefasciatus.to investigate mosquitocidal effects of ethanolic extract of flowers of tagetes erecta (t. erecta) and its chloroform and petroleum ether soluble fractions against the larvae of culex quinquefasciatus (cx. quinquefasciatus).023569756
interlocked feedforward loops control cell-type-specific rhodopsin expression in the drosophila eye.how complex networks of activators and repressors lead to exquisitely specific cell-type determination during development is poorly understood. in the drosophila eye, expression patterns of rhodopsins define at least eight functionally distinct though related subtypes of photoreceptors. here, we describe a role for the transcription factor gene defective proventriculus (dve) as a critical node in the network regulating rhodopsin expression. dve is a shared component of two opposing, interlocked ...021663797
behavioral observations and sound recordings of free-flight mating swarms of ae. aegypti (diptera: culicidae) in thailand.sound plays an important role in the mating behavior of mosquitoes, including aedes aegypti (l). males orient to the fundamental wing beat frequency of females, and both sexes actively modulate their flight tone before mating to converge at harmonic frequencies. the majority of studies on mosquito mating acoustics have been conducted in the laboratory using tethered individuals. in this study, we present the first free-flight recording of naturally forming ae. aegypti swarms in thailand. we desc ...021845959
newer approaches to malaria control.malaria is the third leading cause of death due to infectious diseases affecting around 243 million people, causing 863,000 deaths each year, and is a major public health problem. most of the malarial deaths occur in children below 5 years and is a major contributor of under-five mortality. as a result of environmental and climatic changes, there is a change in vector population and distribution, leading to resurgence of malaria at numerous foci. resistance to antimalarials is a major challenge ...023508211
distributions of competing container mosquitoes depend on detritus types, nutrient ratios, and food availability.coexistence of competitors may result if resources are sufficiently abundant to render competition unimportant, or if species differ in resource requirements. detritus type has been shown to affect interspecific competitive outcomes between aedes albopictus (skuse) and aedes aegypti (l.) larvae under controlled conditions. we assessed the relationships among spatial distributions of detritus types, nutrients, and aquatic larvae of these species in nature. we collected mosquitoes, water, and detr ...022707761
the world of pulmonary vascular disease. 022140619
direct targets of the d. melanogaster dsxf protein and the evolution of sexual development.uncovering the direct regulatory targets of doublesex (dsx) and fruitless (fru) is crucial for an understanding of how they regulate sexual development, morphogenesis, differentiation and adult functions (including behavior) in drosophila melanogaster. using a modified damid approach, we identified 650 dsx-binding regions in the genome from which we then extracted an optimal palindromic 13 bp dsx-binding sequence. this sequence is functional in vivo, and the base identity at each position is imp ...021652649
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