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reference services via electronic mail. 20133947775
neuropharmacological screening of newly-synthesized 2-substituted derivatives of the barbituric acid.neuropharmacological screening is applied of fourteen newly-synthesized 2-substituted derivatives of the barbituric acid (the first seven compounds contain a hydroxylamine group, the rest--a hydrazine group). the derivatives were studied using irwin's screening test (1964), modified by nikolova and daleva (1968), after being introduced intraperitoneally in albino mice of both sexes. excitatory phenomena prevail in the compounds containing the hydrazine group. the derivatives containing hydroxyla ...20133832793
the role of androstenedione and testosterone in the reproduction and antler growth of a male white-tailed deer.seasonal levels of androstenedione and testosterone were investigated in plasma of mature intact and castrated male white-tailed deer. in four intact bucks, androstenedione concentrations were low in february and march (around 1 nmol/l) and then increased significantly (p less than 0.05) from april to november (peak 2.34 nmol/l). testosterone remained low (below 3.5 nmol/l) from february to august and then rose significantly (p less than 0.01) till november (peak 36.78 nmol/l). both hormones dec ...20133811770
an unusual case of cyproheptadine (periactin) overdose in an adolescent female.a 13-year-old female ingested an acute overdose of cyproheptadine hydrochloride (periactin) and presented for treatment. she manifested all the classic signs and symptoms of an acute antihistamine overdose, including psychosis, except for miotic, minimally reactive pupils. the patient was supportively managed. all sequelae of the ingestion resolved within four days, and the child was released from the hospital. we discuss the unusual presentation of miotic pupils in an acute cyproheptadine overd ...20133786225
the potentiating effects of alcohol on driver injury.it is well established that alcohol (ethanol) is associated with increased probability of traumatic injury. this relationship has been attributed to alcohol's impairment of judgment and psychomotor performance, leading to increased probability of an injury-producing mishap. once an accident occurs, it is widely believed that alcohol may protect against injury. however, controlled laboratory studies using animal models indicate that alcohol exacerbates the injurious effects of trauma. in this stu ...20133747064
[pregnancy and functional disorders of the thyroid gland]. 20133719755
correcting a block?: successful experience of a small british pacing centre.the establishment of a local permanent pacemaker service in a district general hospital increased the pacemaker implantation rate from 22 per million population per year to 152 per million population per year over the first 6 years of the service. forty eight per cent of patients were referred by general practitioners and 52% by hospital specialists. single chamber demand pacing (vvi) was used exclusively. indications for pacing and complications were comparable to those of specialist cardiac ce ...20133676039
rupture of atheromatous plaque as a cause of thrombotic occlusion of the internal carotid artery. 20133686595
volmat. a midwife's view. 20133647214
[the language of the eye. expressive functions of the eye].the eye is an effective and frequently used means of communication. innate ocular signals express basic feelings and are identical all over the world. acquired signals depend on cultural status, intelligence, and education. eye diseases and orbital anomalies can provide misleading impressions, because they can be confused with true eye signals or because they can trigger innate reaction mechanisms. surgically, the eye can often be improved as an emittor of signals; the message, however, has to b ...20133573666
gastric ulcers after endoscopic sclerosis of esophageal varices.two patients with bleeding esophageal varices underwent endoscopic sclerosis. each developed a gastric ulcer of the fundic mucosa approximately 6-7 cm below the gastro-esophageal junction. it seems probable that these lesions were related to the retrograde flow of sclerosing solution into the venous system which drains the gastric mucosa.20133872322
obstetric medication and neonatal behavior. current controversies.this article reviews the work on the neonatal effects of low drug doses published in the last five years. at the same time, there will be a focus on new developments in perinatal pharmacology and on current controversies in this area. the article includes discussions about neurobehavioral outcome measures and statistics, as well as recommendations for future studies.20133893844
obstetric medication and neonatal behavior. current controversies.this article reviews the work on the neonatal effects of low drug doses published in the last five years. at the same time, there will be a focus on new developments in perinatal pharmacology and on current controversies in this area. the article includes discussions about neurobehavioral outcome measures and statistics, as well as recommendations for future studies.20133893844
atherosclerosis precursors in finnish children and adolescents. i. general description of the cross-sectional study of 1980, and an account of the children's and families' state of health.the paper describes the general outline of a multicentre study on the risk factors of coronary heart disease (chd) and their determinants in children of various ages in different parts of finland. the study was a cross-sectional one, and was carried out in 1980 in five university cities of finland with medical schools and in 12 rural communities in their vicinity. the randomized sample included an equal number of boys and girls, aged 3, 6, 9, 12, 15, and 18 years, and an equal number of urban an ...20133879091
the use of recommended daily allowances to assess dietary adequacy. 20133797414
[determination of the minimal inhibitory concentration and of the minimal bactericidal concentration. bacteriostatic and bactericidal strength of serum]. 20133851490
low dose urography. a clinical comparison of three low osmolar (ratio 3) contrast media.three modern low osmolar contrast media (iopamiro, omnipaque and hexabrix) were injected intravenously in 150 patients. they were all effective for urography in a concentration iso-osmolar to blood and with a dose of 90 mg i/kg body weight in patients with normal renal function. in patients with decreased renal function, this low dose is not sufficient and should be doubled. no significant diagnostic differences between the three media were found. the subjective and objective adverse effects wer ...20133799228
[bacterial meningitis and intrathecal treatment of chronic pain]. 20133839988
palliative treatment of malignant stenoses of the upper gastrointestinal tract using a combination of laser and afterloading therapy.forty-eight patients with malignant stenoses of the esophagus and cardio-esophageal junction were submitted to endocavitary afterloading treatment after prior endoscopic recanalization with the laser. an intraluminal reduction in tumor mass, and rapid elimination of dysphagia proved possible. this technique represents an alternative to the endoscopic implantation of an endoprosthesis. the afterloading tube is placed endoscopically under direct vision. using a 192iridium radiation source, 7 gy we ...20133709412
long-term follow-up study of patients after endoscopic sphincterotomy for choledocholithiasis.late complications have been examined in 96 patients consecutively treated for choledocholithiasis by endoscopic sphincterotomy in the years 1976 to 1980. forty-four of the patients (46%) had the gallbladder in situ. patients treated for short-term complications--that is, in the 1st month after sphincterotomy--are not included in this study. the mean length of follow-up study was 4.1 years (range, 2 months to 8 years and 9 months). late bile duct symptoms occurred in seven patients (7%): three ( ...20133685877
significance of increased serum lactate dehydrogenase isoenzyme 5 in acute infero-posterior myocardial infarction. 20133690859
postgraduate course: respiratory injury. part iii: pulmonary dysfunction in the burn patient. 20133648051
[dieulafoy disease. a rare cause of upper gastrointestinal hemorrhage]. 20133871983
[dieulafoy disease. a rare cause of upper gastrointestinal hemorrhage]. 20133871983
desmoplastic cartilaginous formation in malignant melanoma. 20133624588
aacn recertification. 20133636238
[modification of tear film break-up time by hormonal contraceptives]. 20133710337
[practice of oriental medicine. 8. etiology and internal and external symptoms]. 20133639179
painful piezogenic pedal papules in patients with ehlers-danlos syndrome.painful piezogenic pedal papules were observed in 10 of 29 patients with ehlers-danlos syndrome. the diagnosis was made by examining each patient while he or she stood with full body weight on the heels and by observing the appearance of the painful papules on the medial, posterior, and lateral aspects of both heels. biopsy specimens of papules demonstrated a thickened and dense dermis. the subcutaneous fibrous trabeculae were thin, with resultant poor compartmentalization of the fat. painful pi ...20133624559
a 15-year follow-up study of 512 consecutive charnley-muller total hip replacements.this article presents a prospective study of 512 consecutive total hip replacements done with the charnley-muller prosthesis. the operations were performed between 1967 and 1972. the follow-up period ranges from 13 1/2 to 18 years (average, 15 years). from the initial 512 replaced hips, only 148 were available for study at the end of 1985. the failure rate due to loosening of the prosthetic components, after a mean follow-up period of 15 years, was approximately 40%. the rate of loosening of the ...20133612141
tumor immunogenicity, nutritional repletion, and cancer.nutritional repletion in cancer reverses malnutrition and its associated immunodepression, but whether it benefits the host-tumor outcome has been variable. this study hypothesizes that such nutritional support will only favor that host generating a potent antitumor immune response. murine neuroblastoma (nb) was characterized into immunizing c1300-nb and nonimmunizing tbj-nb cell lines; and 100 6-week-old strain a mice were assigned on day -14 to isocaloric dietary groups (24% or 2.5% protein). ...20133616915
rodent population in suez canal zone, egypt. 20133572086
a simple substitute for a missing segment of the proximal anterior urethra.we describe 2 patients with an absent segment of the bulbomembranous urethra, in 1 of whom the defect extended from the triangular ligament to the scrotal area. a simple method to restore continuity is presented, which is applicable to a wide variety of conditions resulting in the absence of a long segment of the bulbomembranous urethra.20133669176
osteoarthropathy of the hand and wrist in patients undergoing long-term hemodialysis.radiographs of the hand and wrist in 81 patients who had undergone hemodialysis for a minimum of 5 years (mean, 7.8 years) were reviewed. in 32 patients arthritic changes were found, consisting of articular erosions, joint space narrowings, periarticular cysts, and osteopenia. seven of the 32 patients had periarticular calcific deposits. the frequency and severity of the radiographic findings increased with increasing duration of dialysis. it appears that in addition to the well-recognized secon ...20133588905
[practical child psychology of the dentist]. 20134235714
recently described defects in vitamin b12 metabolism. 20133554021
medical students perceptions of pre-clinical medical ethics teaching. 20133641589
[electrocardiographic monitoring of children with cardiac rhythms disorders]. 20133562162
[care of ventilator patients. monitoring and maintenance of artificial respirators]. 20133859900
fourth international workshop on bone and soft tissue densitometry using computed tomography. fontevraud, france, may 29-june 1, 1984. 20133989065
improvement in men inpatients in an alcoholism rehabilitation unit: a week-by-week comparison.the brief symptom inventory (bsi), a 53-item psychiatric symptom checklist, was administered to 57 alcoholic inpatients on days 2, 10, 18 and 26 of their 28-day stay in an alcoholism rehabilitation unit at a veterans administration hospital. the results of the test show a steady decline in the patients' psychiatric symptomatology from week 1 to week 4 with the most dramatic improvement evidenced between weeks 1 and 2.20133959565
improvement in men inpatients in an alcoholism rehabilitation unit: a week-by-week comparison.the brief symptom inventory (bsi), a 53-item psychiatric symptom checklist, was administered to 57 alcoholic inpatients on days 2, 10, 18 and 26 of their 28-day stay in an alcoholism rehabilitation unit at a veterans administration hospital. the results of the test show a steady decline in the patients' psychiatric symptomatology from week 1 to week 4 with the most dramatic improvement evidenced between weeks 1 and 2.20133959565
[new methods for audiometric evaluation in childhood].impaired speech learning, mental retardation and alterations of affectivity and behaviour may be the consequences of profound neonatal deafness. the authors emphasize the importance of detecting the newborns at audiological risk and screening the neonates in order to get an early diagnosis and treatment of the affection, at least within the first year of life, to avoid or reduce the consequences of hearing loss; then they describe the procedure commonly in use at present for neonatal hearing scr ...20133837251
[clinico-angiographic characteristics of choroid melanoma and their significance in the planning of organ-sparing treatment]. 20133822332
[hospital bacteremias. prospective study of their clinical and epidemiological characteristics]. 20133832248
ultrasound guidance for needle aspiration of the hip in patients with painful hip prosthesis. 20133928697
[laser scanning ophthalmoscopy]. 20133792966
chromosomal and fluorometric dna analyses of malignant histiocytosis. 20133811786
[current problems in pediatric endocrinology]. 20133811424
ethical issues in nursing research. 20133850680
effect of age, sex, and body surface area on echocardiographic left ventricular wall mass in normal subjects.m-mode echocardiography was used to estimate left ventricular wall mass in 136 older normal subjects (group i: 78 men and 58 women, ages 20 to 97 years) and 105 younger normal subjects (group ii: 52 male and 53 female subjects, ages 1 day to 23 years). echocardiographic left ventricular mass (in grams) was estimated from the following formula: left ventricular mass = 1.05 ([ left ventricular internal diastolic dimension + ventricular septal thickness (diastole) + posterior wall thickness (diasto ...20133804398
multiple myeloma mimicking pituitary adenoma.a case of multiple myeloma which presented as a solitary intrasellar tumor is reported. the initial radiographic and light microscopic findings were interpreted as being consistent with pituitary adenoma. subsequently, when systemic disease developed and a bone marrow biopsy demonstrated multiple myeloma, the histopathologic diagnosis of the sellar lesion was established retrospectively.20133791987
high plasma levels of protein c activity and antigen in the nephrotic syndrome.low plasma levels of antithrombin iii due to excessive urinary loss are thought to be the cause of thrombotic complications in patients with the nephrotic syndrome. to see whether protein c (pc), another antithrombotic protein, is also reduced in plasma by the same mechanism, plasma and urinary protein c were determined in 24 patients with nephrotic syndrome and no thrombotic complication, and compared to plasma and urinary antithrombin iii. twenty patients (83%) had high plasma levels of protei ...20133754658
presentation of an unrecognized lymphoma as esophageal tumor.malignant lymphomas rarely cause symptomatic esophageal involvement. we describe a patient presenting with the typical clinical and radiological features of an esophageal tumor. endoscopic findings suggested a malignant tumor different from a carcinoma. histology and cytology of biopsies revealed a highly malignant non-hodgkin's lymphoma (nhl). interestingly, further staging procedures revealed a well-differentiated stage iv nhl. thus, the esophageal tumor must be interpreted as a de-differentia ...20133754207
prediction of long-term outcome in schizophrenia by prognostic scales.the predictive validity of four prognostic scales described in the literature (gittelman-klein scale, goldstein scale, phillips scale, strauss-carpenter scale) and of four newly developed prognostic scores was tested in two long-term followup studies on schizophrenic patients. among the prognostic scales of the literature, the strauss-carpenter scale showed the best results; it reached a level that was attained by only three of the newly developed scales. the three other scales of the literature ...20133715416
sales incentives for marketers. 20133679134
a modified pitot tube for the accurate measurement of tidal volume in children.a device using modification of a pitot tube has been designed for measurement of tidal volume in infants and small children. its accuracy was compared both n vitro and n vivo to that of a calibrated pneumotachograph (fleish #1) designed for a similar flow range. in vitro measurement of air flow with the modified pitot tube (mpt) was within 5% of the pneumotachograph readings over a range of 1-60 l/min. similar accuracy was found with measurement of tidal volumes from 20 ml to 1 l, delivered by a ...20133674477
reversible somatosensory evoked potential changes with neodymium: yttrium-aluminum-garnet laser use.reversible prolongation and dissolution of the tibial somatosensory evoked potential (sep) was observed with operative use of the neodymium:yttrium-aluminum-garnet (nd:yag) laser during extirpation of a foramen magnum meningioma. rapid normalization of the sep followed irrigation with cool saline. the absence of postoperative dorsal column deficit suggests that heat-related physiological changes occurred before the point of irreversible tissue injury. should intraoperative sep monitoring prove a ...20133683778
[tuberculous meningitis and normal glucose in the csf]. 20133659470
[volunteers at a hospital: pleasure in serving from one's free will]. 20133656734
classification of spinal cord vascular malformations.through the aid of developments in the neuroradiological sciences, great attention has been given to the diagnosis and treatment of vascular malformations of the spinal cord. some of these are congenital, such as intramedullary vascular malformations and arteriovenous fistulae supplied by the spinal cord. others are rather frequent and appear in old age. due to their poor prognosis when not treated, precise determinations and sufficient knowledge are of the utmost importance.20134070669
[arm function in patients with quadriplegia after spinal cord injuries]. 20133684754
the segmental nephrogram. 20133875232
burns of the upper extremity in children: long-term evaluation of function following treatment.hand burns in children represent a severe and possibly deforming injury. this study evaluated 82 patients for type of burn, prognostic indicators, and treatment as it affected function and appearance. the best long-term results were associated with small palmar contact burns, compression garments, early skin grafting except for the palm, and late surgical release of webbing. range of motion of the joints in the hand and clinical function were related. however, hand appearance had no correlation ...20133624468
progress curves of reactions catalyzed by unstable enzymes. a theoretical approach.when an enzyme is incubated with its substrate, the rate of catalysis will decline with time due to the combined effects of substrate utilization and product accumulation. these effects will be superimposed upon a progressive loss of catalytic activity if the enzyme is unstable, either spontaneously or as a result of an added reagent. in this report, the effect of enzyme inactivation on the progress curve for an enzyme-catalyzed reaction is considered. it is shown that under most circumstances c ...20133626585
antimicrobial activities of some flavonoid compounds.6 flavonoid compounds, namely kaempferol, quercetin, myricetin, rutin, naringin, and formononetin were separated from different plant materials. they were identified using column and paper chromatography techniques, and physicochemical methods were applied to determine their structure. isolated flavonoids were tested for their antimicrobial property against different bacterial and fungal strains as test organisms.20133811648
[granulocyte alloimmunization during hemotherapy]. 20133719627
[injuries of the extremities in polytraumatized patients: staged treatment]. 20133715477
able elderly in the family context: changes, chances, and challenges. 20133623133
stress and medical illness in the elderly. 20133553904
interactions of oncogenes with haematopoietic cells. 20133536235
usefulness of postoperative enzymes for diagnosis of perioperative myocardial infarction following aortocoronary bypass. 20133879714
[reaction of the eye to absence of the vitreous body]. 20133623377
aqueous micellar systems in membrane protein crystallization. partial miscibility of a nonionic surfactant in the presence of salt or polyethylene glycol.the effects of nacl and polyethylene glycol (peg) 4000 on the lower consolution boundary (lcb) of a nonionic surfactant (c8e5) were studied and compared. micellar systems were nacl and peg 4000 are present are often used in membrane protein crystallization. while sodium chloride shifts the surfactant lcb to lower temperatures without a significant change in the shape of the boundary, peg produces a large solubility change strongly depending on the surfactant concentration. the salt effect is exp ...20133840746
a retrospective study on the effects of steroid administration and prolongation of the latent phase in patients with preterm premature rupture of the membranes.to address the issues of whether corticosteroid treatment and prolongation of the latent phase improve the outcome of pregnancy in patients with preterm premature rupture of the membranes, we studied 96 patients with premature rupture of the membranes who were delivered of infants of adequate weight for gestational age with birth weights between 751 and 2000 gm and who had a latent period longer than 48 hours. of these 96 infants, 53 received treatment with steroids and tocolytic agents and 43 r ...20133706431
autonomic responsiveness to affective visual stimulation in temporal lobe epilepsy.patients with temporal lobe epilepsy (tle) have been posited by some to manifest a syndrome of interictal personality and behavioral change. furthermore, this syndrome has been attributed to an underlying mechanism--enhanced affective responsiveness. the purpose of this investigation was to determine whether patients with tle manifest increased emotional responsiveness relative to appropriate controls. patients with tle (n = 23) were compared with non-tle (n = 7) and healthy controls (n = 16) as ...20133965038
autonomic responsiveness to affective visual stimulation in temporal lobe epilepsy.patients with temporal lobe epilepsy (tle) have been posited by some to manifest a syndrome of interictal personality and behavioral change. furthermore, this syndrome has been attributed to an underlying mechanism--enhanced affective responsiveness. the purpose of this investigation was to determine whether patients with tle manifest increased emotional responsiveness relative to appropriate controls. patients with tle (n = 23) were compared with non-tle (n = 7) and healthy controls (n = 16) as ...20133965038
rapid and sensitive high-performance liquid chromatographic assay for metformin in plasma and urine using ion-pair extraction techniques. 20133734008
small groups in orbit: group interaction and crew performance on space station.orbiting space stations herald a new era of enterprise, but they raise unprecedented issues about crew interaction and performance. it is argued that group interaction, despite its effect on crew performance, is an area largely ignored in current space planning. this article identifies these issues using a model of group interaction and findings from situations similar to orbiting stations. directions for possible solutions and research are noted.20133675462
the vulnerable elderly. 20133639104
follow-up programs for emotionally restored patients: some issues and considerations. 20134317292
follow-up programs for emotionally restored patients: some issues and considerations. 20134317292
[investigation of the selective method for the optimal combination of paper chromatographic solvent systems of 22 kinds of amino acids]. 20134096244
[investigation of the selective method for the optimal combination of paper chromatographic solvent systems of 22 kinds of amino acids]. 20134096244
learning to say "no". 20133792593
electrosurgery: fundamental requirements for successful use. 20133865125
ethical issues in critical care. voluntariness. 20133641820
pathology of fatal rhabdomyosarcoma. report from intergroup rhabdomyosarcoma study (irs-i and irs-ii).patterns of tumor spread were studied by examining clinicopathologic and postmortem data on 274 tumor-related deaths from patients in irs-i and irs-ii. the activity of the primary lesion and presence or absence of distant metastases at death were related to the histologic subtype and anatomic site of origin, individually and/or in combination. the alveolar subtype had the highest proportion of distant metastases and the lowest occurrence of local progression alone from the primary site. more dis ...20133791156
use of csf c-reactive protein in differentiating bacterial and non-bacterial meningitis. 20133681748
infection control for the emergency medical technician: developing an educational program. 20133633704
male pseudohermaphroditism due to 5-alpha-reductase deficiency. clinical and endocrinological data in a 17-year-old patient. 20133747981
leu m1 and s100 in hodgkin's disease and non-hodgkin's lymphomas.leu m1 positivity of reed-sternberg (rs) cells has been reported. the authors studied the specificity and sensitivity of leu m1 in hodgkin's disease (hd) and non-hodgkin's lymphoma (nhl). within nhl, they particularly selected cases that were confused with hd. the authors also studied s100 antigen to determine the pattern of staining in hd and nhl. paraffin-embedded sections of 23 hd cases (3 lymphocyte predominate, 10 nodular sclerosing, 10 mixed cellularity) and 22 nhl cases (13 diffuse large ...20133754087
detection of nonrandom clustering of colonies in agar culture.we report a quantitative method for the detection of clustering in agar cultures. a statistical model was constructed on the assumption that colony formation by a cell in agar culture was independent of its spatial relationship to other cells in the culture. deviation from this model was then tested by a chi-squared test of the actual observations compared with values obtained from the model. this method provides a technique that will identify interactions between cells of like or unlike type. u ...20134029296
prediction of the relative blood glucose response of mixed meals using the white bread glycemic index.unexpected plasma glucose responses to different mixed meals fed to normal and diabetic volunteers have recently been reported. we have therefore examined in normal volunteers the effect of mixing carbohydrate foods of different glycemic indices (gis) without the addition of fat and protein. the observed gi of the mixed meal was within 2% of the expected value. in studies in the literature where fat and protein were added to mixed meals, the observed blood glucose responses also related signific ...20134053930
at least one thalamotelencephalic pathway in cartilaginous fishes projects to the medial pallium.injections of horseradish peroxidase into the medial pallium of the spiny dogfish, squalus acanthias, retrogradely labeled cells in the superficial portion of the dorsal pallium, the medial pallium and the septal area of the telencephalon, and in the posterior tubercle and posterior lateral thalamic nucleus of the diencephalon. except for the septal projection, all projections to the medial pallium are bilateral. labeled fibers could be traced from the injection site to caudal telencephalic leve ...20133627563
[analysis of hba1 is necessary in the routine check-up of patients with type 2 diabetes mellitus]. 20133807486
tissue cea determination and cytophotometric dna analysis of colorectal mucosa in patients with colorectal cancer.determination of tissue cea content and cytophotometric dna analysis of colorectal mucosa were carried out in 45 patients. tissue cea content in mucosa of tumor-bearing patients was significantly higher than in mucosa of the controls. in mucosa of the patients, tissue cea content of transitional mucosa was significantly higher than that of background mucosa. cytophotometric dna analysis of colorectal mucosa disclosed that over 3c cells were not found in the upper third of the crypt in the contro ...20133831499
longitudinal study of dental caries in individuals in jönköping, sweden, aged 15 years in 1973 and 20 years in 1978.the aim of this investigation was to study caries development between the ages of 15 and 20 yr in the same individuals. data concerning 100 adolescents constituted the basic material. eighty subjects could be re-examined 5 yr after the first examination. the mean number of teeth per subject was 27.1 both in 1973 and in 1978. four subjects (4%) in 1973 and three subjects (2.4%) in 1978 showed no decayed and/or filled proximal tooth surfaces. the prevalence of intact tooth regions was higher in th ...20133857143
[perinatal nursing of mothers and infants: psychosocial approach. 9. response to the basic needs of the expectant mothers and the process of acquisition of the maternal role]. 20133643300
[method of preparing combined knock-down models for porcelain and unit-cast crowns]. 20133554619
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