Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| bilateral scrotal abscesses caused by klebsiella pneumoniae in a newborn. | the management of acute scrotal swelling can be challenging in neonatal age, with scrotal infections being great mimickers of testicular torsion. only a few unilateral cases of scrotal abscess have been previously reported, mostly caused by staphylococcus and salmonella. we describe the case of a newborn who developed bilateral scrotal abscesses caused by klebsiella pneumoniae and discuss the rarity of the case, regarding both the bilaterality and the pathogen, never reported before. | 2010 | 20223303 |
| recurrent hemolacria: a sign of scleral buckle infection. | the purpose of this study was to report recurrent hemolacria, or "bloody tears," as a sign of scleral buckle (sb) infection. | 2010 | 20224466 |
| increased isolation of esbl producing klebsiella pneumoniae with emergence of carbapenem resistant isolates in pakistan: report from a tertiary care hospital. | to report trends of extended spectrum beta lactamase (esbl), multidrug resistant (mdr) esbl and emergence of carbapenem resistant esbl producing isolates of k. pneumoniae from pakistan. | 2010 | 20225774 |
| the function of wzy_k1 (maga), the serotype k1 polymerase gene in klebsiella pneumoniae cps gene cluster. | 2010 | 20225957 | |
| in vitro activity of tigecycline against patient isolates collected during phase 3 clinical trials for diabetic foot infections. | the in vitro activity of tigecycline and comparative antimicrobial agents was evaluated against 1828 primary baseline pathogens isolated from 844 patients enrolled in the phase 3 clinical trials investigating the efficacy of tigecycline in diabetic foot infection (dfi). the trials were global, enrolling patients in 30 countries. tigecycline was active against the most prevalent pathogens in dfi, including gram-positive and gram-negative isolates of both aerobic and anaerobic bacteria with 95% of ... | 2010 | 20226331 |
| plasmid-mediated quinolone resistance determinants qnr and aac(6')-ib-cr in escherichia coli and klebsiella spp. from norway and sweden. | the prevalence of the plasmid-mediated quinolone resistance genes qnr and aac(6')-ib-cr was investigated among clinical isolates of escherichia coli and klebsiella spp. selected from 2 collections of consecutive isolates collected in 2004 to 2005 in norway (n = 2479) and sweden (n = 2980) and 1 group of extended-spectrum beta-lactamase (esbl)-producing isolates collected in 2003 in norway (n = 71). a total of 414 isolates was selected for screening based on resistance to nalidixic acid and/or re ... | 2010 | 20226333 |
| bloodstream infections caused by qnr-positive enterobacteriaceae: clinical and microbiologic characteristics and outcomes. | the clinical significance of plasmid-mediated quinolone resistance determinant qnr has not been well characterized. we investigated the clinical and microbiologic characteristics and outcomes of bloodstream infections (bsis) caused by qnr-positive enterobacteriaceae. we prospectively collected 351 nonduplicate consecutive blood isolates of enterobacter spp. and klebsiella pneumoniae. qnr genes were detected by polymerase chain reaction and confirmed by sequencing. the medical records of patients ... | 2010 | 20227228 |
| genetic background of quinolone resistance in ctx-m-15-producing klebsiella pneumonia and escherichia coli strains in tunisia. | 2010 | 20227997 | |
| design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. | in the present investigation, a series of novel {5-chloro-2-[(3-(substitutedphenyl)-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones (3a-i) have been synthesized from 5-(chloromethyl)-3-substitutedphenyl-1,2,4-oxadiazole (2a-i). the newly synthesized compounds were characterized by ir, nmr (1h and 13c), mass spectral and elemental analysis. the title compounds were investigated for in-vitro qualitative (zone of inhibition) and quantitative (mic) antibacterial activity by agar cup plate ... | 2010 | 20231043 |
| comparison of the efficacy of rose bengal and erythrosin in photodynamic therapy against enterobacteriaceae. | the aim of this study was to evaluate the effects of the photosensitizers rose bengal and erythrosin combined with a light-emitting diode (led) on enterobacteriaceae. twelve enterobacteriaceae strains isolated from the oral cavities of patients undergoing prolonged antibiotic therapy, including three escherichia coli, three enterobacter cloacae, three klebsiella oxytoca and three klebsiella pneumoniae, were studied. an enterobacteriaceae suspension (10(6) cells/ml) was prepared from each clinica ... | 2010 | 20232222 |
| synthesis of 1-(4-methoxybenzyl)-3-cyclopropyl-1h-pyrazol-5-amine derivatives as antimicrobial agents. | a series of novel substituted 1-(4-methoxybenzyl)-3-cyclopropyl-1h-pyrazol-5-amine benzamides 9(a-h) were synthesized to determine their antibacterial and antifungal activities as well as possible structure-activity relationships (sars) to improve therapeutic efficacy. the pyrazol-5-amine benzamides were screened for their antibacterial activity against standard strains of gram-positive (streptococcus pyogenes ncim 2608, staphylococcus aureus atcc 29737, bacillus subtilis ncim 2010) and gram-neg ... | 2010 | 20235748 |
| development and evaluation of oligonucleotide chip based on the 16s-23s rrna gene spacer region for detection of pathogenic microorganisms associated with sepsis. | oligonucleotide chips targeting the bacterial internal transcribed spacer region (its) of the 16s-23s rrna gene, which contains genus- and species-specific regions, were developed and evaluated. forty-three sequences were designed consisting of 1 universal, 3 gram stain-specific, 9 genus-specific, and 30 species-specific probes. the specificity of the probes was confirmed using bacterial type strains including 54 of 52 species belonging to 18 genera. the performance of the probes was evaluated u ... | 2010 | 20237100 |
| the udp-galp mutase catalyzed isomerization: synthesis and evaluation of 1,4-anhydro-beta-d-galactopyranose and its [2.2.2] methylene homologue. | the synthesis of 1,4-anhydro-beta-d-galactopyranose (1,5-anhydro-alpha-d-galactofuranose), a proposed intermediate in the ring contraction isomerisation catalyzed by udp-galactopyranose mutase, together with its [2.2.2] bicyclic methylene homologue, synthesised as a possible competitive inhibitor or alternative substrate, are reported. neither compound was found to be an inhibitor or substrate for udp-galactopyranose mutase from klebsiella pneumoniae. | 2010 | 20237670 |
| in situ polytetrafluoroethylene graft bypass for primary infected aneurysm of the infrarenal abdominal aorta. | reinfection is a major issue of surgical treatment for patients with infected abdominal aortic aneurysm (aaa). the present report describes outcomes after use of our procedure for treating patients with infected aneurysm of the infrarenal abdominal aorta. the procedure involved an in situ polytetrafluoroethylene (ptfe) graft bypass and omental wrapping of the graft. the procedure was used regardless of the presence of gram-stain-positive pus or tissue or the type of pathogen identified. | 2010 | 20238215 |
| management of antibiotic resistance in the intensive care unit setting. | over the past few decades, an alarming increase of infections caused by antibiotic-resistant pathogens, including methicillin-resistant staphylococcus aureus, vancomycin-resistant enterococcus species, carbapenem-resistant pseudomonas aeruginosa, extended-spectrum beta-lactamase-producing escherichia coli and klebsiella spp., and multidrug-resistant acinetobacter spp., has been observed, particularly in intensive care units. for clinicians, the rising resistance rate observed in nosocomial patho ... | 2010 | 20192683 |
| antibiotic-associated hemorrhagic colitis caused by cytotoxin-producing klebsiella oxytoca. | klebsiella oxytoca was recently described as the causative organism for antibiotic-associated hemorrhagic colitis (aahc). it is currently not known if this novel gastrointestinal infection exists in children. aahc is usually preceded by antibiotic treatment with penicillins, which are frequently prescribed for pediatric patients. in contrast to colitis caused by clostridium difficile, colitis caused by k oxytoca is usually segmental and located predominantly in the right colon. patients with aah ... | 2010 | 20194278 |
| klebsiella pneumoniae orbital cellulitis with extensive vascular occlusions in a patient with type 2 diabetes. | a 39-year-old woman visited the emergency room complaining of right eye pain and swelling over the preceding three days. the ophthalmologist's examination revealed orbital cellulitis and diabetic retinopathy in the right eye, although the patient had no prior diagnosis of diabetes. it was therefore suspected that she had diabetes and orbital cellulitis, and she was started on multiple antibiotic therapies initially. she then underwent computed tomography scans of the orbit and neck and magnetic ... | 2010 | 20195414 |
| immune responses of helicoverpa armigera to different kinds of pathogens. | insects react against pathogens through innate immunity. the cotton bollworm helicoverpa armigera (h. armigera) is an important defoliator and an extremely destructive pest insect of many crops. the elucidation of the mechanism of the immune response of h. armigera to various pathogens can provide a theoretical basis for new approaches to biologically control this pest. | 2010 | 20196874 |
| [change of esbls-kpn and esbls-eco after antimicrobial intervention]. | to evaluate the change of extended spectrum beta-lactamase (esbls) producing klebsiella pneumoniae (esbls-kpn) and escherichia coli (esbls-eco) causing nosocomial infection after antimicrobial intervention. | 2010 | 20197617 |
| [investigation of nosocomial infection in the neonatal intensive care unit]. | a perspective study was conducted to describe the epidemiologic profile of nosocomial infection in the neonatal intensive care unit (nicu). | 2010 | 20199716 |
| outbreak of infection with klebsiella pneumoniae sequence type 258 producing klebsiella pneumoniae carbapenemase 3 in an intensive care unit in italy. | 2010 | 20200298 | |
| application of real-time pcr, dgge fingerprinting, and culture-based method to evaluate the effectiveness of intrinsic bioremediation on the control of petroleum-hydrocarbon plume. | real-time polymerase chain reaction (pcr), denaturing gradient gel electrophoresis (dgge), and the culture-based method were applied in the intrinsic bioremediation study at a petroleum-hydrocarbon contaminated site. the genes of phenol hydroxylase (phe), ring-hydroxylating toluene monooxygenase (rmo), naphthalene dioxygenase (nah), toluene monooxygenase (tol), toluene dioxygenase (tod), and biphenyl dioxygenase (bph4) were quantified by real-time pcr. results show that phe gene was detected in ... | 2010 | 20185233 |
| transmission of a klebsiella pneumoniae clone harbouring genes for ctx-m-15-like and shv-112 enzymes in a neonatal intensive care unit of a kuwaiti hospital. | the spread of antibiotic-resistant bacteria has become a large problem in most countries including kuwait. this antibiotic resistance is usually due to the production of extended-spectrum beta-lactamase (esbl) enzymes such as shv, tem and ctx-m. this study reports the emergence and spread of an esbl-producing klebsiella pneumoniae clone in a neonatal intensive care unit (nicu) in a kuwaiti hospital. eight esbl-producing k. pneumoniae isolates were from blood cultures of seven neonates, and two w ... | 2010 | 20185547 |
| [chronic abdominal aortic graft infection : detection with 18f-fdg-pet/ct]. | a 67-year-old male patient presented with recurrent fever and septic emboli due to an aorto-duodenal fistula after previous aortobiiliac bypass grafting with suspected graft infection. imaging by ultrasound, computed tomography scan (ct) and magnetic resonance imaging (mri) could not confirm graft infection. a scan using 2-deoxy-2-fluoro-[18f]-d-glucose positron emission tomography ct (18f-fdg-pet/ct) revealed a pathological uptake. the bifurcated graft was removed und revascularization was perf ... | 2010 | 20186379 |
| in vitro activities of fosfomycin and carbapenem combinations against carbapenem non-susceptible escherichia coli and klebsiella pneumoniae. | 2010 | 20189774 | |
| 2-chloroadenosine (2-cado) treatment modulates the pro-inflammatory immune response to prevent acute lung inflammation in balb/c mice suffering from klebsiella pneumoniae b5055-induced pneumonia. | acute lung inflammation (ali) is a life-threatening pathology and can develop during the course of several clinical conditions such as pneumonia, acid aspiration or sepsis. adenosine plays a significant role in controlling acute inflammation via binding to a(2a) receptors on inflammatory cells, i.e. neutrophils or macrophages. the present study was designed to evaluate the anti-inflammatory and immunomodulatory effects of 2-chloroadenosine (2-cado), alone or in combination with amoxicillin/clavu ... | 2010 | 20189776 |
| microwave-assisted, solvent-free and parallel synthesis of some novel substituted imidazoles of biological interest. | solvent free microwave assisted synthesis of some novel substituted imidazoles of biological interest is reported. first, primary aromatic or heteryl amine was condensed with aryl or heteryl aldehydes to afford corresponding schiff's base. the schiff's base further on treatment with ammonium acetate (nh(4)oac) and isatin using silica gel as the solid support, yielded the corresponding aryl imidazoles. in this paper a comparative study between the developed microwave method and conventional metho ... | 2010 | 20190444 |
| eleven-year study of causes of neonatal bacterial meningitis in ahvaz, iran. | bacterial meningitis is a devastating infection with a high mortality rate, especially in neonates. the aim of this study was to determine the causative agents that cause bacterial meningitis in khuzestan province in the south-western region of iran. | 2010 | 20202151 |
| first description of klebsiella pneumoniae clinical isolates carrying both qnra and qnrb genes in portugal. | in the present study, 21 multidrug-resistant klebsiella pneumoniae isolates were recovered from patients hospitalised in the intensive care unit of hospital infante d. pedro in aveiro, portugal. fifteen isolates carried qnr genes. four strains harboured the quinolone resistance genes qnra and qnrb, both located on a large plasmid in two strains (kp4 and kp10) and on different plasmids in two strains (kp5 and kp6). these findings indicate an extremely high prevalence of qnr genes associated with ... | 2010 | 20202799 |
| characteristics of plasmid-mediated quinolone resistance genes in extended-spectrum cephalosporin-resistant isolates of klebsiella pneumoniae and escherichia coli in korea. | quinolone resistance is frequently associated with extended-spectrum cephalosporin resistance in enterobacteriaceae. | 2010 | 20203489 |
| the analysis of multiple genome comparisons in genus escherichia and its application to the discovery of uncharacterised metabolic genes in uropathogenic escherichia coli cft073. | a survey of a complete gene synteny comparison has been carried out between twenty fully sequenced strains from the genus escherichia with the aim of finding yet uncharacterised genes implicated in the metabolism of uropathogenic strains of e. coli (upec). several sets of adjacent colinear genes have been identified which are present in all four upec included in this study (cft073, f11, uti89, and 536), annotated with putative metabolic functions, but are not found in any other strains considere ... | 2010 | 20204180 |
| detection of the first two klebsiella pneumoniae isolates with sequence type 258 producing kpc-2 carbapenemase in denmark. | 2010 | 20206479 | |
| characterization of the klebsiella aerogenes urease accessory protein ured in fusion with the maltose binding protein. | assembly of the klebsiella aerogenes urease metallocenter requires four accessory proteins, ured, uree, uref, and ureg, to effectively deliver and incorporate two ni2+ ions into the nascent active site of the urease apoprotein (ureabc). each accessory protein has been purified and characterized with the exception of ured due to its insolubility when it is overproduced in recombinant cells. in this study, a translational fusion was made between the maltose binding protein (mbp) and ured, with the ... | 2010 | 20207756 |
| 2,3-dihydroxypropane-1-sulfonate degraded by cupriavidus pinatubonensis jmp134: purification of dihydroxypropanesulfonate 3-dehydrogenase. | 2,3-dihydroxypropane-1-sulfonate (dhps) is a widespread intermediate in plant and algal transformations of sulfoquinovose (sq) from the plant sulfolipid sulfoquinovosyl diacylglycerol. further, dhps is recovered quantitatively during bacterial degradation of sq by klebsiella sp. strain abr11. dhps is also a putative precursor of sulfolactate in e.g. ruegeria pomeroyi dss-3. a bioinformatic approach indicated that some 28 organisms with sequenced genomes might degrade dhps inducibly via sulfolact ... | 2010 | 20150239 |
| genotypic detection and molecular epidemiology of extended-spectrum beta-lactamase-producing escherichia coli and klebsiella pneumoniae in a regional hospital in central taiwan. | this study was conducted to detect the genes encoding extended-spectrum beta-lactamases (esbls) and determine the epidemiological relatedness of 69 escherichia coli and 33 klebsiella pneumoniae isolates collected from a regional hospital in central taiwan, mostly from inpatients (e. coli 87.0%; k. pneumoniae 88.0%). the phenotypes of these isolates were examined according to the combination disc method recommended by the clinical and laboratory standards institute. most of the esbl-producing e. ... | 2010 | 20150317 |
| risk factors in community-acquired urinary tract infections caused by esbl-producing bacteria in children. | in this study, risk factors were investigated in children with community-acquired urinary tract infections (uti) caused by extended-spectrum beta-lactamases (esbl)-producing e. coli or klebsiella spp. one hundred and fifty-five patients were diagnosed with esbl-positive uti (case group) in the outpatient clinics of hacettepe university children's hospital between 1 january 2004 and 31 december 2006. a control group, 155 out of 4,105 children, was matched by age and sex among children with esbl-n ... | 2010 | 20151161 |
| antimicrobial susceptibility of moxifloxacin against gram-negative enteric rods from colombian patients with chronic periodontitis. | gram-negative enteric rods were associated with periodontal diseases in several populations. the association between enteric and putative periodontal pathogens has received little attention in the literature. the present investigation determined the occurrence and in vitro antimicrobial susceptibility of isolates of gram-negative enteric rods from colombian patients with chronic periodontitis. | 2010 | 20151809 |
| influencing factors in the occurrence of injured coliforms in the drinking water distribution system in the city of la plata, argentina. | the objective of this study was to evaluate the influencing factors in the occurrence of coliforms in the drinking water in la plata (argentina) from june 1999 to june 2001. a total of 180 samples were collected from rio de la plata (102 samples) and puelche aquifer (78 samples); 45 samples were collected for each of the four seasons. the membrane filter procedure was used for isolating bacteria, and each sample was tested for chlorine and ph. the highest percentage of samples positive for colif ... | 2010 | 20154384 |
| relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from klebsiella pneumoniae by rational design. | 1,3-propanediol has wide applications for large volume markets, particularly in the polymer business. microbial production of 1,3-propanediol has been considered as a competitor to the traditional petrochemical routes. however, the formation of 1,3-propanediol is limited by the amount of nadh supplied by the oxidative pathway of glycerol dismutation. previous metabolic flux analysis revealed that relaxation of the coenzyme specificity of 1,3-propanediol oxidoreductase for both nadh and nadph wou ... | 2010 | 20156491 |
| "typhlitis" in rectum. | 2010 | 20158643 | |
| klebsiella oxytoca-positive, penicillin-associated hemorrhagic enterocolitis in children. | 2010 | 20158656 | |
| extended-spectrum beta-lactamase-producing bacteria and vesicoureteral reflux in children. | 2010 | 20158657 | |
| alterations in cytokines and effects of dexamethasone immunosuppression during subclinical infections of invasive klebsiella pneumoniae with hypermucoviscosity phenotype in rhesus (macaca mulatta) and cynomolgus (macaca fascicularis) macaques. | invasive klebsiella pneumoniae with the hypermucoviscosity phenotype (hmv k. pneumoniae) is an emerging human pathogen that also has been attributed to fatal multisystemic disease in african green monkeys at our institution. combining a cluster of subclinically infected macaques identified in march and april 2008 and the animals documented during a subsequent survey of more than 300 colony nonhuman primates yielded a total of 9 rhesus macaques and 6 cynomolgus macaques that were subclinically in ... | 2010 | 20158951 |
| efflux pumps are involved in the defense of gram-negative bacteria against the natural products isobavachalcone and diospyrone. | the activities of two naturally occurring compounds, isobavachalcone and diospyrone, against documented strains and multidrug-resistant (mdr) gram-negative bacterial isolates were evaluated. the results indicated that the two compounds exhibited intrinsic antibacterial activity against several gram-negative bacteria, and their activities were significantly improved in the presence of an efflux pump inhibitor (mic values decreased to below 10 microg/ml). in addition, the activities of isobavachal ... | 2010 | 20160051 |
| susceptibility of carbapenemase-producing strains of klebsiella pneumoniae and escherichia coli to the direct antibacterial activity of nab739 and to the synergistic activity of nab7061 with rifampicin and clarithromycin. | to determine the susceptibility of carbapenemase-producing strains of klebsiella pneumoniae and escherichia coli to the direct antibacterial activity of nab739 and to the synergistic activity of nab7061 with rifampicin and clarithromycin. nab739 and nab7061 are novel polymyxin derivatives that lack the cationic charges in the linear peptide portion of polymyxin b and have pharmacokinetic properties different from those of polymyxin b. | 2010 | 20167589 |
| pediatric urinary tract infections in a tertiary care center from north india. | paediatric urinary tract infections (uti) are associated with high morbidity and long term complications like renal scarring, hypertension, and chronic renal failure. a cause of occult febrile illness, they often remain undiagnosed. we studied the clinical and microbiologic profile and antibiotic resistance profile of such infections in paediatric uti patients at our center. | 2010 | 20167982 |
| molecular characterisation of trimethoprim resistance in escherichia coli and klebsiella pneumoniae during a two year intervention on trimethoprim use. | trimethoprim resistance is increasing in enterobacteriaceae. in 2004-2006 an intervention on trimethoprim use was conducted in kronoberg county, sweden, resulting in 85% reduction in trimethoprim prescriptions. we investigated the distribution of dihydrofolate reductase (dfr)-genes and integrons in escherichia coli and klebsiella pneumoniae and the effect of the intervention on this distribution. | 2010 | 20169085 |
| sialidase-based anti-influenza virus therapy protects against secondary pneumococcal infection. | das181 (fludase) is a sialidase fusion protein in clinical development as a broad-spectrum anti-influenza virus (ifv) therapeutic agent. previous reports by other investigators have raised the concern that desialylation of airway epithelium might increase susceptibility to streptococcus pneumoniae infection. | 2010 | 20170378 |
| [postoperative infection due to contaminated propofol]. | seven patients operated on in a period of two consecutive days in the havenziekenhuis, rotterdam, the netherlands developed symptoms of sepsis following a relatively minor procedure. one patient developed fever and hypotension a few hours after surgery, and developed thrombocytopenia and leucopenia. postoperative bleeding occurred as a result of the thrombocytopenia, necessitating further surgery. this patient developed serious multi-organ failure, and required prolonged intensive care treatment ... | 2010 | 20170564 |
| sepsis and its etiology among hospitalized children less than 1 year of age with intestinal failure on parenteral nutrition. | infections accompany intestinal failure (if) more commonly in children than in adults, with reported incidences of 2% to 29%. appropriate care of the central venous catheter is the most important factor preventing infections; but in addition, bacteria translocate from the dysmotile gut as a possible source of septicemia. the aim of this retrospective analysis was to investigate the rate and the epidemiologic profile of septicemia in the patient group at greatest risk, namely, children less than ... | 2010 | 20172274 |
| [extended-spectrum beta-lactamases in enterobacteria other than escherichia coli and klebsiella]. | methods for detecting esbl-producing enterobacteriaceae begin by a correct interpretation of the susceptibility profiles, applying the usual criteria for interpretative reading of the antibiogram. appropriate confirmatory methods will be consequently chosen, based on the inhibition of the enzyme by betalactamases inhibitors, generally clavulanic acid. in case of non-ampc-producing enterobacteriaceae, at least two substrates should be used -cefotaxime or ceftriaxone and ceftazidime- to detect enz ... | 2010 | 20172418 |
| [urinary pneumococcal or legionella antigen detection tests and low-spectrum antibiotic therapy for community-acquired pneumonia]. | we performed urinary antigen tests for pneumococcus and legionella for patients with community-acquired pneumonia (cap), to prescribe a documented antibiotic therapy. we report the efficiency of low-spectrum antibiotic treatment, illustrating the inappropriateness of bacteriological respiratory sampling. | 2010 | 20172672 |
| successful control of an outbreak of klebsiella pneumoniae carbapenemase-producing k. pneumoniae at a long-term acute care hospital. | to determine the effect of a bundle of infection control interventions on the horizontal transmission of klebsiella pneumoniae carbapenemase (kpc)-producing k. pneumoniae during an outbreak. | 2010 | 20175685 |
| natural history of colonization with gram-negative multidrug-resistant organisms among hospitalized patients. | to determine the anatomic sites and natural history of colonization with gram-negative multidrug-resistant organisms (mdros). | 2010 | 20175687 |
| antimicrobial activity of the extracts of craniotome furcata (lamiaceae). | craniotome furcata (link.) o. kuntze (lamiaceae) is used in the traditional medicine for the treatment of cuts and wounds indicating antimicrobial activity. | 2010 | 20176098 |
| international nosocomial infection control consortium (inicc) report, data summary for 2003-2008, issued june 2009. | we report the results of the international infection control consortium (inicc) surveillance study from january 2003 through december 2008 in 173 intensive care units (icus) in latin america, asia, africa, and europe. during the 6-year study, using centers for disease control and prevention (cdc) us national healthcare safety network (nhsn; formerly the national nosocomial infection surveillance system [nnis]) definitions for device-associated health care-associated infection, we collected prosp ... | 2010 | 20176284 |
| colistin administration to pediatric and neonatal patients. | emergence of multidrug-resistant gram-negative nosocomial pathogens has led to resurgence of colistin use. safety and efficacy data regarding colistin use in pediatric patients are sparse, while optimal dosage has not been defined. we present a case series of neonates and children without cystic fibrosis treated with various doses of colistin intravenously. the records of patients who received colistin in a tertiary-care hospital from january 2007 to march 2009 were reviewed. thirteen patients ( ... | 2010 | 20119725 |
| emergence of kpc-producing klebsiella pneumoniae in italy. | abstract: | 2010 | 20178590 |
| a case-control study of risk factors for urinary acquisition of klebsiella pneumoniae producing ctx-m-15 in an outbreak situation in sweden. | a retrospective case-control study was initiated at uppsala university hospital in 2006 during a major outbreak caused by a klebsiella pneumoniae strain producing ctx-m-15. to identify risk factors associated with acquisition of the outbreak strain in the urinary tract, 52 case patients with a urine culture positive for the outbreak strain between 1 may and 31 december 2005 were enrolled. case patients were matched 1:2 with concurrently hospitalized control patients with significant growth of su ... | 2010 | 20180680 |
| prevalence and antibiotic resistance pattern of metallo-beta-lactamase-producing pseudomonas aeruginosa from burn patients--experience of an indian tertiary care hospital. | the objective of the study is to determine the prevalence of pseudomonas aeruginosa from burn patients, antibiotic resistance pattern and occurrence of acquired mbl-producing p. aeruginosa among isolates collected from burn patients. in this study, two phenotypic methods were used for the detection of mbl-producing p. aeruginosa: zone enhancement with edta-impregnated imipenem and ceftazidime discs, and modified hodge test. one hundred fifty-four isolates of p. aeruginosa were obtained from july ... | 2010 | 20182377 |
| detection of ges-5-producing klebsiella pneumoniae in brazil. | 2010 | 20139141 | |
| response to the letter to the editor by j silver 're: case report: a fatal metastasis of klebsiella pneumonia of the lungs'. | 2010 | 20142833 | |
| histamine, cadaverine, and putrescine produced in vitro by enterobacteriaceae and pseudomonadaceae isolated from spinach. | a total of 364 bacterial isolates, obtained from spinach leaves, were assayed in a decarboxylase broth containing histidine, lysine, and ornithine to check their ability to produce biogenic amines, and then quantified by high-performance liquid chromatography. among these isolates, 240 formed cadaverine, 208 formed putrescine, and 196 formed histamine, in widely varying amounts. they frequently produced more than one biogenic amine. klebsiella pneumoniae subsp. pneumoniae and morganella morganii ... | 2010 | 20132689 |
| isethionate formation from taurine in chromohalobacter salexigens: purification of sulfoacetaldehyde reductase. | bacterial generation of isethionate (2-hydroxyethanesulfonate) from taurine (2-aminoethanesulfonate) by anaerobic gut bacteria was established in 1980. that phenomenon in pure culture was recognized as a pathway of assimilation of taurine-nitrogen. based on the latter work, we predicted from genome-sequence data that the marine gammaproteobacterium chromohalobacter salexigens dsm 3043 would exhibit this trait. quantitative conversion of taurine to isethionate, identified by mass spectrometry, wa ... | 2010 | 20133363 |
| nosocomial infections in neonatal intensive care units: profile, risk factor assessment and antibiogram. | to determine the profile and risk factors of neonatal nosocomial infections and determine the antibiotic susceptibilities of these isolates. | 2010 | 20135266 |
| in vitro biological activities of niloticane, a new bioactive cassane diterpene from the bark of acacia nilotica subsp. kraussiana. | acacia nilotica subsp. kraussiana was reported in african traditional medicine for the treatment of various ailments. isolation of an active compound in this study from the bark extract may lead to the validation of its efficiency as a traditional crude drug. | 2010 | 20138134 |
| carriage of genes for various extended-spectrum beta-lactamases: a novel resistance strategy of klebsiella pneumoniae in poland. | among 110 randomly sampled strains from a collection of 247 extended-spectrum beta-lactamase (esbl)-producing clinical isolates of klebsiella pneumoniae collected from hospitalised children in three paediatric hospitals in poland, 64 strains (58.2%) with multiple esbls were found, including five non-clonal strains (4.5%) harbouring bla genes for esbls of three families (ctx-m, shv and tem). this is the first report of the emergence of triple esbl-producing k. pneumoniae in poland. in addition, k ... | 2010 | 20138476 |
| stereospecific synthesis of oximes and oxime ethers of 3-azabicycles: a sar study towards antimicrobial agents. | libraries of 1-methyl-2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones/oximes/o-methyloximes 1-14/15-28/29-42 and 7-methyl-2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones/oximes/o-methyloximes 43-48/49-54/55-60 were synthesized and their stereochemistry was established by 1d/2d nmr spectral and single crystal xrd studies. all the synthesized oximes and oxime ethers were screened for their in vitro antimicrobial activity against a panel of pathogenic bacteria (bacillus subtilis, staphylococcus aureus, klebs ... | 2010 | 20138517 |
| evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm? | 2010 | 20121112 | |
| extended-spectrum beta-lactamase-producing escherichia coli in patients with travellers' diarrhoea. | the identification of patients carrying extended-spectrum beta-lactamase (esbl)-producing bacteria is important, since these patients are at risk of receiving inappropriate empirical therapy if they become infected. the purpose of this study was to investigate the occurrence of esbl-producing bacteria in patients with travellers' diarrhoea. patients with travellers' diarrhoea (n = 242) having delivered stool samples for the diagnosis of salmonella, shigella, yersinia or campylobacter, were also ... | 2010 | 20121649 |
| suppurative adenitis of preputial glands associated with corynebacterium mastitidis infection in mice. | suppuration of the preputial gland in mice occurs as a septic complication of fight wounds around the external genitalia. currently reported bacterial isolates from these lesions are limited to staphylococcus aureus, pasteurella pneumotropica, and klebsiella oxytoca. in the context of a pilot experiment aimed at defining the aging phenotype of estrogen receptor beta knockout (berko) mice, 2 male mice (1 of the berko line and the other from the age- and sex-matched wild-type control group) were d ... | 2010 | 20122320 |
| structural fold, conservation and fe(ii) binding of the intracellular domain of prokaryote feob. | feob is a g-protein coupled membrane protein essential for fe(ii) uptake in prokaryotes. here, we report the crystal structures of the intracellular domain of feob (nfeob) from klebsiella pneumoniae (kpnfeob) and pyrococcus furiosus (pfnfeob) with and without bound ligands. in the structures, a canonical g-protein domain (g domain) is followed by a helical bundle domain (s-domain), which despite its lack of sequence similarity between species is structurally conserved. in the nucleotide-free sta ... | 2010 | 20123128 |
| in vitro activity of penem-1 in combination with beta-lactams against blakpc-possessing klebsiella pneumoniae isolates. | 2010 | 20124003 | |
| fosfomycin for the treatment of multidrug-resistant, including extended-spectrum beta-lactamase producing, enterobacteriaceae infections: a systematic review. | rising rates of resistance to antimicrobial drugs among enterobacteriaceae limit the choice of reliably active forms of these drugs. we evaluated the evidence on fosfomycin as a treatment option for infections caused by members of the family enterobacteriaceae with advanced resistance to antimicrobial drugs, including producers of extended-spectrum beta-lactamase (esbl). we systematically reviewed studies evaluating the antimicrobial activity, or the clinical effectiveness of fosfomycin. 17 anti ... | 2010 | 20129148 |
| biodegradation of propionitrile by klebsiella oxytoca immobilized in alginate and cellulose triacetate gel. | a microbial process for the degradation of propionitrile by klebsiella oxytoca was studied. the microorganism, k. oxytoca, was isolated from the discharged wastewater of metal plating factory in southern taiwan and adapted for propionitrile biodegradation. the free and immobilized cells of k. oxytoca were then examined for their capabilities on degrading propionitrile under various conditions. alginate (al) and cellulose triacetate (ct) techniques were applied for the preparation of immobilized ... | 2010 | 20129732 |
| [emphysematous pyelonephritis]. | emphysematous pyelonephritis (epn) is a rare, life-threatening infection of the kidney, characterized by production of gas within the renal parenchyma or perinephric tissue. escherichia coli and klebsiella are the most commonly isolated organisms. most patients are diabetics. ct is diagnostic. within half a year two patients with epn were admitted. they were successfully treated with internal/percutaneous drainage (pcd), and antibiotics. earlier, acute nephrectomy was first choice treatment, but ... | 2010 | 20089217 |
| spread of plasmids containing the bla(vim-1) and bla(ctx-m) genes and the qnr determinant in enterobacter cloacae, klebsiella pneumoniae and klebsiella oxytoca isolates. | we describe 12 vim-1-producing strains (7 enterobacter cloacae, 2 klebsiella pneumoniae and 3 clonal klebsiella oxytoca strains) detected among clinically relevant enterobacteriaceae isolates from routine cultures at the hospital del mar (barcelona, spain) from december 2006 to may 2007. | 2010 | 20089541 |
| [laryngeal stenosis as late manifestation of rhinoscleroma. case report]. | rhinoscleroma is a chronic, progressive, granulomatous disease resulting from infection with klebsiella rhinoscleromatis. it is generally uncommon, but endemic in certain regions of the world. it typically affects the nasal cavity, but also other parts of the respiratory system, such as the laryngotracheal region, which may be life-threatening if compromised. we present a 46-year-old male patient with a history of rhinoscleroma diagnosed and treated 15 years ago, with subglottal stenosis as a la ... | 2010 | 20092805 |
| clinical characteristics of post-neurosurgical klebsiella pneumoniae meningitis in adults and a clinical comparison to the spontaneous form in a taiwanese population. | a total of 46 patients (nine post-neurosurgical, 37 spontaneous) with adult bacterial meningitis (abm) caused by klebsiellapneumoniae infection were included in this study. the nine patients in the post-neurosurgical k. pneumoniae abm group (seven male, two female) had a mean age of 48.9 years. two patients in this group also had diabetes mellitus (dm) and one had liver disease. the most common presentation of patients in post-neurosurgical k. pneumoniae abm group was fever (nine patients), foll ... | 2010 | 20093030 |
| microbiological study of pathogenic bacteria isolated from paediatric wound infections following the 2008 wenchuan earthquake. | on 12 may 2008, the wenchuan earthquake struck in sichuan, china. within 1 month after the earthquake, 98 injured children were admitted to the children's hospital of chongqing medical university. according to clinical manifestations, 50 children were diagnosed with wound infections. wound secretions were cultured for bacteria. pathogen distribution and drug resistance were analyzed. a total of 99 pathogens were isolated; 16 (16%) were gram-positive bacteria and 81 (82%) were gram-negative bacte ... | 2010 | 20095936 |
| contamination of laryngoscope handles. | despite use of sterile or disposable laryngoscope blades for each patient, disinfection of laryngoscope handles does not routinely occur, and these devices present a potential route of transmission of pathogens between patients and staff. a total of 192 specimens from 64 laryngoscope handles deemed 'ready for patient use' in the anaesthetic rooms of 32 operating theatres were semiquantitatively assessed for bacterial contamination. a further 116 specimens from 58 of the handles were tested for o ... | 2010 | 20096953 |
| synthesis and in vitro microbiological evaluation of an array of biolabile 2-morpholino-n-(4,6-diarylpyrimidin-2-yl)acetamides. | biolabile 2-morpholino-n-(4,6-diarylpyrimidin-2-yl)acetamides 34-42 have been synthesized and evaluated for their in vitro antibacterial and antifungal activities. the minimum inhibitory concentration tested for the same compounds against the same set of bacterial and fungal strains shows that the compounds 36 and 38 against beta-heamolytic streptococcus and klebsiella pneumonia, 40 against escherichia coli and pseudomonas, have excellent antibacterial activity. compounds 36, 38 and 42 show inhi ... | 2010 | 20106563 |
| risk factors for bloodstream infection with klebsiella pneumoniae producing vim-1 metallo-beta-lactamase. | to identify risk factors for bloodstream infections (bsis) caused by vim-1-producing klebsiella pneumoniae (vpkp). | 2010 | 20106862 |
| in vitro activities of doripenem and other carbapenems against clinically important bacteria isolated in intensive care units: nationwide data from the smart programme. | this nationwide surveillance of clinically important bacteria from the intensive care units (icus) of major teaching hospitals throughout taiwan investigated the susceptibilities to doripenem and other comparator carbapenems from september through november 2005. minimum inhibitory concentrations (mics) were determined for 1,311 clinical isolates using the broth microdilution method according to clinical and laboratory standards institute (clsi) 2005 guidelines. doripenem showed similar (within f ... | 2010 | 20108018 |
| risks factors for infections with extended-spectrum beta-lactamase-producing escherichia coli and klebsiella pneumoniae at a tertiary care university hospital in switzerland. | there are considerable geographical differences in the occurrence of extended-spectrum beta-lactamase(esbl)-producing bacteria, both in the community and in the hospital setting. our aim was to assess risk factors for blood stream, urinary tract, and vascular catheter-associated infections with esbl-producing escherichia coli and klebsiella pneumoniae at a tertiary care hospital in a low-prevalence country. | 2010 | 20108162 |
| molecular epidemiology of multidrug resistant extended spectrum beta-lactamase producing klebsiella pneumoniae at a jamaican hospital, 2000-2004. | the accurate identification of a pathogen beyond the species level is critical in epidemiological studies and investigations of nosocomial outbreaks of infection. the clonal relatedness of 66 multidrug resistant (mdr) strains of extended spectrum beta-lactamase (esbl) producing k. pneumoniae isolated from clinical specimens from hospitalized patients at a jamaican hospital during a 5 year period were determined by pulsed field gel electrophoresis (pfge). | 2010 | 20109209 |
| antibacterial activity of artemisia nilagirica leaf extracts against clinical and phytopathogenic bacteria. | the six organic solvent extracts of artemisia nilagirica were screened for the potential antimicrobial activity against phytopathogens and clinically important standard reference bacterial strains. | 2010 | 20109237 |
| pcr characterization and typing of klebsiella pneumoniae using capsular type-specific, variable number tandem repeat and virulence gene targets. | a multiplex pcr is described which detects capsular types k1, k2, k5, k54 and k57, which are those most associated with invasive disease or pathogenicity, a further capsular type (k20), two putative virulence factors (rmpa and wcag) and the 16s-23s internal transcribed spacer unit of klebsiella pneumoniae, facilitating identification of this organism. wcag encodes capsular fucose production and was associated with capsular types k1 and k54, but was also found in strains of other capsular types; ... | 2010 | 20110386 |
| design, recombinant expression, and antibacterial activity of the cecropins-melittin hybrid antimicrobial peptides. | in order to evaluate their antibacterial activities and toxicities, the cecropins-melittin hybrid antimicrobial peptide, ca(1-7)-m(4-11) (cam) and cb(1-7)-m(4-11) (cbm), were designed by apd2 database. the recombinant hybrid antimicrobial peptides were successfully expressed and purified in pichia pastoris. antimicrobial activity assay showed that both of the two hybrid antimicrobial peptides had strong antibacterial abilities against escherichia coli, staphylococcus aureus, pseudomonas aerugino ... | 2010 | 20111863 |
| important methodological considerations with respect to differentiation of ctx-m-15 and ctx-m-28 extended-spectrum beta-lactamases. | 2010 | 20061778 | |
| epidemiology and outcome of klebsiella species bloodstream infection: a population-based study. | to determine incidence rate, seasonal variation, and short- and long-term outcomes of klebsiella species bloodstream infection (bsi) in a population-based setting. | 2010 | 20118389 |
| antimicrobial resistance among clinical isolates from the chinese meropenem surveillance study (cmss), 2003-2008. | the chinese meropenem surveillance study (cmss) programme was initiated in 2003 with the aim of monitoring the antimicrobial activity of broad-spectrum agents against nosocomial gram-negative bacilli in china. from 2003 to 2008, a total of 3892 isolates were collected from 10 teaching hospitals. the minimum inhibitory concentrations (mics) of 11 antimicrobial agents were determined by the agar dilution method. during the study period, a marked decrease in the susceptibility of acinetobacter spp. ... | 2010 | 20047820 |
| synthesis and antimicrobial activities of novel 1,5-diaryl pyrazoles. | novel 1,5-diaryl pyrazole derivatives viz. 5-(4-chlorophenyl)-1-(4-fluorophenyl)-1h-pyrazole-3-carboxamides (2a-e, 3, 3a-f), 2-(5-(4-chlorophenyl)-1-(4-fluorophenyl)-1h-pyrazole-3-yl)thiazoles (6a-c,7, 8, 9a-c, 10, 11) were synthesized by varying the active part (amide group) of pyrazole, characterized using ir, (1)h nmr, mass spectral data and screened for their antibacterial activity against escherichia coli (attc-25922), staphylococcus aureus (attc-25923), pseudomonas aeruginosa (attc-27853), ... | 2010 | 20053480 |
| molecular characterization of extended-spectrum beta-lactamases in clinical escherichia coli and klebsiella pneumoniae isolates from surabaya, indonesia. | no detailed reports regarding extended-spectrum beta-lactamase (esbl)-producing enterobacteriaceae are currently available from indonesia, the fourth most populous country in the world. | 2010 | 20053690 |
| antiserum against raoultella terrigena atcc 33257 identifies a large number of raoultella and klebsiella clinical isolates as serotype o12. | raoultella terrigena atcc 33257, recently reclassified from the genus klebsiella, is a drinking water isolate and belongs to a large group of non-typeable klebsiella and raoultella strains. using an o-antiserum against a capsule-deficient mutant of this strain, we could show a high prevalence (10.5%) of the r. terrigena o-serotype among non-typeable, clinical klebsiella and raoultella isolates. we observed a strong serological cross-reaction with the k. pneumoniae o12 reference strain, indicatin ... | 2010 | 20053705 |
| cytotoxic effects of klebsiella oxytoca strains isolated from patients with antibiotic-associated hemorrhagic colitis or other diseases caused by infections and from healthy subjects. | antibiotic-associated hemorrhagic colitis (aahc) is associated with klebsiella oxytoca. this study analyzed whether cytotoxic properties are linked to specific subtypes of k. oxytoca. klebsiella isolates from stools of aahc patients, healthy carriers, and diarrhea patients as well as from infections of other organs were investigated. cytotoxic effects on human epithelial cells were limited to the species k. oxytoca and were not detectable for any other klebsiella species. isolates from aahc pati ... | 2010 | 20053860 |
| curcumin alone and in combination with augmentin protects against pulmonary inflammation and acute lung injury generated during klebsiella pneumoniae b5055-induced lung infection in balb/c mice. | acute lung injuries due to acute lung infections remain a major cause of mortality. thus a combination of an antibiotic and a compound with immunomodulatory and anti-inflammatory activities can help to overcome acute lung infection-induced injuries. curcumin derived from the rhizome of turmeric has been used for decades and it exhibits anti-inflammatory, anti-carcinogenic, immunomodulatory properties by downregulation of various inflammatory mediators. keeping these properties in mind, we invest ... | 2010 | 20056776 |
| genetic determinants of antibiotic resistance in diarrheagenic klebsiella pneumoniae subspecies ozaenae: an emerging enteropathogen in senegal. | 2010 | 20064035 | |
| human pathogens abundant in the bacterial metagenome of cigarettes. | many studies have evaluated chemical, heavy metal, and other abiotic substances present in cigarettes and their roles in the development of lung cancer and other diseases, yet no studies have comprehensively evaluated bacterial diversity of cigarettes and the possible impacts of these microbes on respiratory illnesses in smokers and exposed nonsmokers. | 2010 | 20064769 |
| surveillance and correlation of antibiotic prescription and resistance of gram-negative bacteria in singaporean hospitals. | a surveillance study was performed in four singapore public hospitals from 2006 to 2008 to determine the correlation between antibiotic prescription and gram-negative bacterial antimicrobial resistance. targeted organisms included ceftriaxone- and ciprofloxacin-resistant escherichia coli and klebsiella pneumoniae, as well as imipenem-resistant pseudomonas aeruginosa and acinetobacter spp. antibiotic prescription data were collated in the who anatomical therapeutic chemical (atc)/defined daily do ... | 2010 | 20065055 |