Publications

in vitro susceptibility to antimycotics of microsporum canis isolates from cats.	one hundred thirty-four isolates of microsporum canis, obtained from cats, were tested for in vitro susceptibility to various antifungal agents. the fungi were classified as susceptible, resistant, and intermediate by measuring the size of the zone of inhibited growth on yeast nitrogen base agar medium. clotrimazole had the highest activity (99.2%), followed by tioconazole (89.6%), griseofulvin (88.8%), econazole (73.1%), ketoconazole (50.7%), miconazole (15.7%), and isoconazole (12.7%). we foun ...	1992	1429182
microsporum gypseum complex in man and animals.	twenty-eight strains of the microsporum gypseum complex isolated from humans and animals were studied. the perfect form was found for 25 of the isolates. nannizzia incurvata was the species most frequently involved in human pathology, while nannizzia gypsea was most frequently found on animal lesions. nannizzia fulva was rarely involved pathologically and nannizzia corniculata was not isolated during this study. it is surprising to note that this species was not found even though most of our str ...	1992	1432489
superficial mycoses in saudi arabia.	between june 1988 and december 1990, 1018 cases of superficial mycoses were investigated. diagnosis was confirmed by microscopic examination in 503 cases and the causal agent was isolated in 490 cases. tinea capitis accounted for 47.7% (92.5% in children below 10 years of age). the frequency of other clinical types in descending order was pityriasis versicolor 25.8%, tinea corporis 9%, onychomycosis 5.8%, tinea pedis 4%, intertrigo 3.9% and tinea cruris 2.8%. erythrasma was encountered three tim ...	1992	1445094
keratinolytic fungi in egyptian soils. i. baited with hair and wool.	150 soil samples were collected, 90 from nile valley and delta, 36 from desert and 24 from salt marshes. human, buffalo and cow hair and sheep wool were used as baits at three incubation temperatures. forty-four species which belong to twenty-one genera at 27 degrees c and forty-two which belong to twenty-two genera at 37 degrees c were collected. we isolated the following keratinophilic fungi chrysosporium tropicum, c. keratinophilum, c. indicum, c. pannicola, c. queenslandicum, trichophyton te ...	1992	1471440
preliminary report on the isolation of a dysgonic variety of microsporum canis together with the normal variety from a cattery.	the isolation of a dysgonic variety of microsporum canis from a large number of cats and kittens in a cattery is described. the normal variety of this fungus was isolated at the same time from the same animals. dysgonic varieties are thought to be mutants of normal strains, but this isolation of both forms together suggests that the relationship may be more complex.	1992	1480210
widespread dermatophytosis due to microsporum (trichophyton) gallinae in a patient with aids--a case report from spain.	we report the case of a 25-year-old, hiv-positive patient (group iv, a, c2 clinical stage) with a widespread dermatophyte infection. he was a male gypsy with a known history of intravenous drug abuse. after an episode of cerebral toxoplasmosis for which he was treated with systemic steroids (because of cerebral oedema) he developed, over 16 days, a remarkably extensive ringworm of the trunk due to an unusual zoophilic dermatophyte, microsporum (trichophyton) gallinae. human infection with this d ...	1992	1486716
extensive dermatophytoses caused by trichophyton mentagrophytes and microsporum canis in a patient with aids.	retrospective studies have shown the occurrence of episodes of deep or superficial fungal infections in 58 to 81% of hiv/aids patients as a result of impairment of cell immunity. we describe a case of disseminated cutaneous dermatophytoses caused by trichophyton mentagrophytes and microsporum canis in a patients with aids. diagnostic and therapeutic problems in relation to this unusual presentation are emphasized as well as the importance of an early mycologic diagnosis to prescribe antifungal t ...	1992	1494359
is microsporum canis infection about to become a serious dermatological problem?	in europe, especially in the mediterranean, the incidence of microsporum canis infection has been on a steep increase during the recent years. in some countries (italy) and geographic areas (slovenia), m. canis is the most often isolated dermatophyte. in slovenia (yugoslavia), a dramatic increase in the incidence of m. canis infection has been observed recently, both in absolute figures and as compared to the rest of isolated dermatophytes. m. canis is a cause of tinea most prevalent in children ...	1992	1498385
control of zoopathogenic fungi in vitro by polyamine biosynthesis inhibitors.	effect of inhibitors of polyamine (pa) biosynthesis, alpha-difluoromethylornithine (dfmo), methylglyoxal bis (guanylhydrazone)--mgbg and bis (cyclohexylammonium) sulphate (bcha) on mycelial growth of three clinically important fungi-trichophyton mentagrophytes, microsporum gypseum and aspergillus flavus was examined in vitro. all inhibitors at concentrations 1 to 50 mm produced greater inhibition of mycelial growth in all fungi tested in a dose-dependent manner. mgbg was the most effective inhib ...	1992	1506039
dermatophytosis of children in kuwait.	five hundred fifty-six children constituted 39.5% of total smear- and culture-positive cases of dermatophytosis and 0.6% of the total new dermatology outpatients seen over a period of five years. males outnumbered females. the youngest child was a 20-day-old neonate (age range 20 days-12 yrs) with a peak of fungal infections seen in patients between 4 and 6 years of age. microsporum canis was the most prevalent (70.5%) species, followed by trichophyton violaceum, microsporum audouinii, trichophy ...	1992	1574472
tinea capitis caused by microsporum canis in a newborn.		1992	1587671
biotypes of the dermatophyte microsporum distortum.	during a study of the epidemiology of microsporum canis and closely related species, sub-specific variation was demonstrated within thirteen isolates of microsporum distortum based on the pattern of carbohydrate utilization. strains from three continents could be differentiated by their utilization of trehalose and erythritol. isolates from new zealand yielded the same patterns as m. canis (arthroderma otae (-)); examination of 120 isolates indicated that m. canis could not be biotyped by carboh ...	1992	1474986
solanum chrysotrichum (schldl.) a plant used in mexico for the treatment of skin mycosis.	an ethnobotanical field study carried out in 200 rural communities determined that the leaves of solanum chrysotrichum schldl. are used in mexican traditional medicine for the treatment of skin mycosis, being particularly recommended to cure tinae pedis. clinical trials were performed using a cream containing 5% of a methanolic leaf extract of this plant. results showed that 45% of the patients were completely cured after 4 weeks of topical treatment. the rest of the cases improved notably in co ...	1992	1608268
in vitro activity of sertaconazole.	the activity of 7-chloro-3-[1-(2,4-dichlorophenyl)-2-(1h-imidazol-1-yl) ethoxy-methyl]benzo[b]thiophene (sertaconazole, fi 7045, cas 99592-32-2), a new topical antifungal, was studied in vitro against several infecting organisms. the results obtained show that sertaconazole is a broad-spectrum antifungal against yeasts (c. albicans, c. tropicalis, c. pseudotropicalis, c. krusei, trichosporon and cryptococcus), dermatophytes (microsporum, trichophyton and epidermophyton), opportunistic filamentou ...	1992	1627186
[tinea corporis caused by microsporum gypseum].	human infections due to microsporum gypseum are rare. we report on a female patient who had tinea corporis caused by m. gypseum after a cutaneous wound. the numerous lesions located on the borders of the wound had an eczematous appearance.	1991	1757260
disinfectants in the control of small animal ringworm due to microsporum canis.	twelve disinfectant products or compounds were evaluated for their ability to kill microsporum canis harvested from naturally infected material. the disinfectants were diluted to the concentration recommended for the disinfection of clean surfaces and the potency of each substance was determined by the degree to which it could be further diluted before losing its fungicidal action. hypochlorite, benzalkonium chloride and glutaraldehyde based compounds were the most effective agents and phenolics ...	1991	1957460
polyacrylamide gel electrophoresis patterns of some microsporum species.	the paper reports observations made of various microsporum species during a page pattern study of the epidemiology of microsporum canis. it is shown that m. audouinii can readily be distinguished from m. canis but that m. equinum is more difficult to separate. m. rivalierii was distinguishable from m. audouinii, confirming previous reports. m. distortum could not be separated from m. canis by page gels of total protein or by isozyme patterns generated. there are particular problems with studies ...	1991	1803231
antifungal activity of two benzofuran-imidazoles in different experimental conditions.	a number of experiments was performed in order to analyze the in vitro activity of two new benzofuran-imidazoles, im/b/4-62 and im/b/4-66. studies included the determination of minimum inhibitory concentrations (mics) on three culture media, at different ph values and at different inoculum sizes. furthermore, the killing activity and induced resistance were determined. in all the experiments econazole, clotrimazole and bifonazole were the reference compounds. the best mic values of the two new i ...	1991	1809809
an atypical microsporum canis isolate.	an atypical strain of microsporum canis isolated from a two-year-old boy with tinea corporis is described. when cultured on lactritmel agar the strain presented the typical pigment of m. canis without developing characteristic macroconidia. after 6 weeks, scarce, rudimentary, fusiform macroconidia 120-150 microns long developed on lactritmel and sablac microcultures. in vitro, the strain developed hair perforating organs. experimental inoculation of a healthy volunteer produced a tinea with typi ...	1991	1824421
tinea capitis in the united arab emirates.	the authors reviewed the causative agents for tinea capitis in united arab emirates nationals attending tawam hospital, al ain, between 1981 and 1988. microsporum canis was the most prevalent organism isolated. oral griseofulvin remained the treatment of choice. the addition of isotretinoin appeared promising in the chronic inflammatory forms.	1991	2001903
sparse diversity of potential pathogenic soil micro-fungi in the ukraine.	soil from steppe and garden reserves, and urban park and wharf regions in the ukraine, u.s.s.r., were studied for keratinophilic as well as for other predominant micro-fungal species. most of the fungi were nonpathogens, and potential skin infecting fungi were limited to microsporum gypseum and trichophyton ajelloi. species diversity identified population variation between collection sites.	1991	2030648
tinea capitis in three adults.	three cases of tinea capitis in healthy adults are presented. in light of the very low incidence (less than 1%) of tinea capitis in nonimmunocompromised adults and the possibility of contagion from asymptomatic dermatophyte carriers in the pediatric and adult populations, the necessity for heightened clinical suspicion and diagnostic tenacity in the evaluation of adults with scalp dermatitis and/or alopecia for possible tinea capitis is underscored.	1991	2037407
kerion masquerading as erosive pustular dermatosis of the scalp.		1991	2039734
fungal flora of the coat of pet cats.	the fungal flora of the coat of 172 healthy pet cats was examined qualitatively. fungi were isolated from 136 (79%) of the 172 cats. fifteen genera were isolated; 13 are commonly regarded as saprophytes, and 2 (microsporum and trichophyton) are commonly regarded as pathogens. aspergillus, alternaria, penicillium, and cladosporium spp were the most frequently isolated saprophytes. dermatophytic fungi, including microsporum gypseum (n = 1), m vanbreuseghemii (n = 1), and trichophyton rubrum (n = 1 ...	1991	2053732
plants used in guatemala for the treatment of dermatophytic infections. 1. screening for antimycotic activity of 44 plant extracts.	skin infections are common diseases in developing countries, of which dermatophytoses are of particular concern in the tropics, especially in infants. through ethnobotanical surveys and literature review 100 plants were detected as being used in guatemala for the treatment of dermatophytoses. of these, 44 plants were screened for in vitro activity against the most common dermatophytes (epidermophyton floccosum, microsporum canis, microsporum gypseum, trichophyton mentagrophytes and trichophyton ...	1991	2056755
review of dermatophytoses in galicia from 1951 to 1987, and comparison with other areas of spain.	we have reviewed all the dermatophytoses diagnosed in galicia during four consecutive 9-year periods 1951-86 and 1987. from 4571 patients, we isolated 3351 fungal strains belonging, in decreasing order of frequency, to the following dermatophyte species: microsporum canis (25.5%), trichophyton rubrum (24.6%), t. mentagrophytes (21.4%), epidermophyton floccosum (11.8%), m. gypseum (5.2%), t. tonsurans (3.9%), t. verrucosum (3.1%), t. schoenlenii (2.5%), t. violaceum (1.2%), t. mengninii (0.3%), m ...	1991	2034261
studies on the mode of action of tolnaftate in microsporum gypseum.	studies were performed on the mode of action of tolnaftate and resistance to this drug in microsporum gypseum. cells grown in the presence of tolnaftate (at the ic 50) showed a reduced content of total phospholipids and sterols whereas there was an increase in total rna content. incubation of cells with tolnaftate (at 10 x mic), followed by addition of different macromolecule precursors revealed inhibition of the biosynthesis of all macromolecules except for rna. the activity of membrane-bound e ...	1991	2061794
isolation of keratinophilic fungi from soil in malaysia.	two hundred and thirty soil samples from different localities were examined for the presence of geophilic keratinophilic fungi. six species namely microsporum gypseum--34 isolates, chrysosporium keratinophilum--29, c. tropicum--20, keratinophyton terreum--4, trichophyton terrestre--8 and chrysosporium species--3--were isolated. most of these fungi were recovered from garden, field and river bank soil. the importance of these findings is briefly discussed.	1991	2067562
fungal skin infections associated with animal contact.	zoophilic dermatophytes are fungal organisms that primarily infect animals but occasionally infect humans. the most common of these are microsporum canis and trichophyton mentagrophytes. the clinical lesions of zoophilic fungal infections are more inflammatory than those caused by the typical anthropophilic fungi normally transmitted from person to person. to diagnose zoophilic fungal infections, a potassium hydroxide preparation of the skin scrapings may be examined microscopically or a culture ...	1991	2008813
mycologic study of tinea capitis in qatar.	the causative dermatophytic species of tinea capitis were identified in 91 patients in qatar. microsporum canis was the most common isolated organism (86.81%) followed by microsporum ferrugineum and trichophyton violaceum. a gray patch type of tinea capitis was the predominant presentation (87.91%), and the disease was more prevalent among qatari boys.	1991	2037406
saprophytic and keratinolytic fungi associated with animals hair from riyadh, saudi arabia.	hair samples from different animals collected from different sites in riyadh, saudi arabia were examined for the presence of saprophytic and keratinolytic fungi. fifty-one specimens were examined of which 19 were from rabbits, 13 from sheeps, 12 from camels and 7 from horses. forty-eight species and one variety which belong to 24 genera were collected during this investigation. the most common genera were aspergillus and chrysosporium. in low frequency, members of the genera thermoascus, scopula ...	1991	1882596
microsporidiosis in hiv-1 infected individuals.		1991	1677148
inflammatory tinea capitis caused by microsporum gypseum in a five-year-old girl.	an otherwise healthy five-year-old girl presented for evaluation of a large patch of erythematous scaling alopecia on the vertex of her scalp. previous attempts to treat this with various topical agents resulted in no improvement. our evaluation included examination of fungal cultures, which grew out a colony with characteristic morphology of microsporum gypseum, supported by lactolphenol blue tease mounts, demonstrating the characteristic conidia for this fungus. treatment was begun with oral g ...	1991	1764960
a clinical and laboratory study of ciclopirox olamine (8% batrafen) in the treatment of onychomycosis.	ciclopirox olamine, a new synthetic substituted pyridone derivative, is an antimycotic agent with activity against a broad spectrum of pathogenic and nonpathogenic fungi. the clinical efficacy and safety of 8% ciclopirox olamine nail liquor were evaluated in 100 cases with finger (or great toe) onychomycosis. after 16 weeks and 24 weeks of treatment for finger and great toe onychomycosis, respectively, the overall therapeutic results were excellent in 36 cases, good in 17, fair in 24, and poor i ...	1991	1838936
influence of aminophylline on the lipids in microsporum gypseum.	the effect of aminophylline on the lipid synthesis of microsporum gypseum has been examined. a decreased incorporation of [14c]acetate into lipids was observed when the cells were incubated for 1 h with aminophylline which was reflected in all the individual lipid fractions. however, cells grown with aminophylline in the growth medium exhibited increased levels of total phospholipids, which was probably due to a rise in intracellular camp as these cells exhibited 4-fold increased levels of camp. ...	1991	1846758
an outbreak of tinea corporis among schoolgirls.		1991	1861933
endemic microsporum canis infection in a sheep flock.		1991	2043092
a survey of dermatophytes from human patients in the united states from 1985 to 1987.	a survey of dermatophytes isolated from patients seeking medical advice was made from 1985 to 1987 in the united states. the survey included 54 locations with data from 45 cities and one state. listing of the isolated dermatophytes and the frequency given by percentage of the total follows: trichophyton rubrum 54.8%, t. tonsurans 31.3%, t. mentagrophytes 6.0%, microsporum canis 4.0%, epidermophyton floccosum 2.0%, m. gypseum 0.6%, and t. verrucosum 0.2%. out of a total of 14,696 isolates m. audo ...	1991	1875984
fungal flora of the haircoat of cats with and without dermatophytosis.	in catteries with a long-standing problem of dermatophytosis, microsporum canis was the sole fungal isolate from all cats, regardless of clinical signs. fungal isolates from cats in catteries with an early problem of m. canis infection (less than 30 days) consisted of m. canis mixed with saprophytic fungi, fewer cats with pure m. canis cultures and individual cats that were culture negative for m. canis. when these catteries were resampled at a later date, m. canis was the only fungus isolated f ...	1991	1955948
[in vitro antifungal activities of amorolfine against fresh isolates from patients with cutaneous mycosis].	in vitro antifungal activities of amorolfine (mt-861), a new morpholine antifungal agent, were examined using an agar-dilution method, in comparison with those of 2 other antifungal agents, clotrimazole (ctz) and bifonazole (bfz), against 182 clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, microsporum canis, and epidermophyton floccosum, which had been freshly isolated from a total of 182 cutaneous mycotic patients with various types of dermatophytes or cutaneous candidias ...	1991	1960850
prevalence of superficial mycoses in the aosta valley region of italy from 1984 to 1989.	this report represents the results of the culture tests for fungi carried out in the aosta valley region of italy from 1984 to 1989. the pathological material consisted of cutaneous scales, hair and nails. it was possible to identify 91.8% of the isolates: out of these, 36.1% were dermatophytes, 21% were aspergillus spp, 15.6% deuteromycetes, 15% yeasts and 4.1% members of the family mucoraceae. the resulting data indicate that microsporum canis was the most wide-spread species (73.7%) among the ...	1991	1795730
fungal infection as a cause of skin disease in the eastern province of saudi arabia: tinea corporis and tinea cruris.	in the period between april 1984 and april 1988 a total of 4,294 clinically suspected cases of dermatomycoses were examined for causative fungi. of these cases 768 (17.9%) were suspected as tinea corporis (427 cases) and tinea cruris (341 cases). twenty two different nationalities were represented. both sexes were involved and the age range was 19 days to 70 years. of the 768 patients examined, 738 (96.1%) had their diagnosis confirmed by direct microscopy and in 631 of these positive cases the ...	1991	1820522
nonscalp hair infection caused by microsporum canis in patient with acquired immunodeficiency syndrome.		1991	1869658
novel broad-spectrum metal-based antifungal agents. correlations amongst the structural and biological properties of copper (ii) 2-acetylpyridine n4-dialkylthiosemicarbazones.	copper(ii) complexes of the type [cu(l)x], where l = tridentate anion of 2-acetylpyridine n4-diethyl thiosemicarbazone and x = c1 or br, were screened against seven fungal strains pathogenic to man viz. aspergillus niger, aspergillus fumigatus, candida albicans, cryptococcus neoformans, tricophyton rubrum, epidermophyton floccosum and microsporum canis. the greater growth inhibition exhibited by the bromo complex can be explained on the basis of its lower cu(ii)/cu(i) redox couple and greater co ...	1991	1931432
favus in a backyard flock of game chickens.	favus, or avian ringworm, was diagnosed in a backyard flock of game chickens from which microsporum gallinae was isolated. infected birds had white crusts on the comb and on the skin of the head and neck. histopathological lesions included hyperkeratosis of the skin epithelium with invasion of the stratum corneum by fungal mycelia, acanthosis, acantholysis, and hydropic degeneration of cells in the stratum spinosum. the underlying dermis was infiltrated by mononuclear cells and contained lymphoi ...	1991	1953587
dermatophytoses in cusco (peru).	a total of 90 cases of suspected dermatophytoses was observed over a period of 9 months in the city of cusco (peru) and in its environs. the age groups most commonly infected were 1-10 and 11-20 year old. the most common tineae diagnosed were tinea capitis (13.3%) and tinea unguium (11.1%). only four species of dermatophytes were isolated: microsporum canis (52.4%), trichophyton mentagrophytes (35.7%), tr. rubrum (9.5%) and epidermophyton floccosum (2.4%). dry weather, low temperature and high a ...	1991	1749399
biochemical and morphological effects of polyamine biosynthesis inhibitors on trichophyton and microsporum.	the minimum inhibitory concentrations (mics) of three known irreversible inhibitors of polyamine synthesis, alpha-difluoromethylornithine (dfmo) and monofluoromethyldehydroornithine methylester (mfmome), inhibitors of ornithine decarboxylase (odc) and alpha-difluoromethylarginine (dfma), an inhibitor of arginine decarboxylase (adc), were determined for 10 species of dermatophytic fungi. trichophyton species were generally more sensitive to these inhibitors than microsporum species. both genera p ...	1991	1880681
trichophyton rubrum invasion of human hair apparatus in tinea capitis and tinea barbae: light- and electron microscopic study.	we have previously reported morphological changes of trichophyton violaceum and microsporum canis in hair apparatuses in tinea capitis. to investigate the morphology of trichophyton rubrum in the human hair apparatus, two cases of tinea capitis and one case of tinea barbae were examined by light- and electron microscopy. the fungal elements, which were located in the lower keratogenous zone, showed non-septate hyphae in the outer part of the hair cortex. with the upward development of the hair l ...	1991	1929541
screening the keratinolytic activity of dermatophytes in vitro.	sixteen strains out of 12 species dermatophytes were examined in respect to their ability of utilizing keratin substrates as the only sources of c and n. the employed keratin substrates included a solubilized preparation of feather keratin (ks) and native keratin, guinea pig hair and chicken feathers. it has been shown that the preparation ks constitutes a convenient model for a preliminary estimation of fungal keratinolytic activity and it can be a source of information about the localization o ...	1991	1713301
dermatophytosis in children and adolescents: epidemiological, clinical, and microbiological aspects changing with age.	during a four year period, a total of 84 cases of dermatophytosis were seen in patients from 0 to 17 years of age attending our out-patient department. the sex distribution was about equal in preadolescents. males predominated among adolescents. a peak incidence at early school age was due to cases of tinea capitis, mainly caused by microsporum canis. a peak among adolescents was due to cases of tinea pedis, mainly caused by trichophyton rubrum. in general, patients with trichophyton rubrum infe ...	1991	1761791
[outbreak of dermatophytosis caused by microsporum canis in a closed community in the province of soria].		1991	1932251
tinea corporis due to microsporum canis from an asymptomatic dog.	the patient was a 19-year-old female student who purchased a puppy from a pet shop four weeks earlier. at the time of her first examination, an annular edematous erythema with adherent scales and vesicles surrounding its margin was seen on the left forearm. on direct examination of the vesicles, fungal elements were detected, and microsporum canis was isolated. the puppy was a pomeranian and was kept in the house at all times. no clinical lesions were seen on the puppy, and the wood's lamp test ...	1991	1939864
fungal infection as a cause of skin disease in the eastern province of saudi arabia: prevailing fungi and pattern of infection.	a total of 4,294 clinically suspected cases of dermatomycoses belonging to 26 different nationalities were examined between april 1984 and april 1988. fungi were demonstrated in routine potassium hydroxide/dimethyl sulfoxide mount in 3,814 cases (88.8%) and the etiology was determined by culture in 2,458 cases (57.2%). tinea versicolor was the predominant fungal infection (30.9% of all infections). onychomycosis and paronychia ranked second in prevalence (16.8%). candidal onychomycosis was the m ...	1991	1803238
[in vitro antifungal activity of itraconazole, a new triazole antifungal agent, against clinical isolates from patients with dermatomycoses].	in vitro antifungal activities of itraconazole (itz), a triazole antifungal agent, against clinical isolates obtained from patients with superficial and subcutaneous mycoses were examined using the agar dilution method on casitone agar. the clinical isolates tested were 7 species and 263 isolates including trichophyton mentagrophytes (104 isolates), trichophyton rubrum (103 isolates), microsporum canis (3 isolates), epidermophyton floccosum (2 isolates), candida albicans (32 isolates), malassezi ...	1991	1652655
diagnosis of enterocytozoon bieneusi microsporidiosis in aids patients by recovery of spores from faeces.		1990	1975888
the occurrence of keratinophilic fungi in sewage sludge from egypt.	the keratinophilic fungi of 40 sewage sludge samples from upper egypt were studied using a goat hair-baiting technique. 43 species representing 22 genera were isolated, 17 species of which were dermatophytes and closely related fungi: chrysosporium state of arthroderma tuberculatum, c. asperatum, c. georgii, c. indicum, c. keratinophilum, c. pseudomerdarium, c. queenslandicum, chrysosporium state of thielavia sepedonium, c. tropicum, microsporum cookei, m. gypseum, myceliophthora anamorph of cor ...	1990	1693678
case for diagnosis. panniculitis, pyogranulomatous, diffuse, severe, with numerous fungal aggregates; etiology--consistent with deep dermatophytosis.		1990	2125345
keratinophilic and saprophytic fungi isolated from students' nails in egypt.	in order to determine the presence of dermatophytes and saprophytes in healthy toe and finger nails, 120 students (60 male and 60 female) from preparatory schools at sohag governorate (upper egypt) were studied. 54 species in addition to 3 varieties belonging to 17 genera were isolated. six species of true dermatophytes were collected: microsporum audouinii var. rivalieri, m. cookei, trichophyton mentagrophytes, t. simii, t. terrestre and t. verrucosum. chrysosporium, a well-known keratinophilic ...	1990	2338622
management of dermatophyte infections in catteries and multiple-cat households.	successful elimination of dermatophytosis from cats requires clipping of the haircoat, weekly or twice-weekly antifungal dips, and systemic antifungal therapy. in addition, the environment should be repeatedly decontaminated with an appropriate chemical, for example, household bleach. successful treatment may take weeks to months depending on the circumstances. monitoring response to therapy is best done via toothbrush-culturing techniques and inoculation of the bristles onto fungal culture medi ...	1990	2251736
in vitro susceptibility of dermatophytes from munich to griseofulvin, miconazole and ketoconazole.	various recent clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, microsporum canis and epidermophyton floccosum from munich were subjected to antimicrobial susceptibility testing using the microdilution method. both azoles miconazole and ketoconazole were found to be more active than griseofulvin. comparatively high inhibitory concentrations of griseofulvin were especially found with tr. mentagrophytes. on the whole miconazole turned out to be even somewhat more effective th ...	1990	2359418
[clinico-epidemiological findings in tinea capitis in adults].	clinical and epidemiological data on 15 subjects with tinea capitis are reported. the patients, aged between 19 and 74, were observed from 1.1.1980 to 30.6.1990; 14 of them were females. the evidence of different clinical pictures is stressed. microsporum canis was isolated in 7 cases, trichophyton violaceum in 6 cases, and trichophyton schoenleinii in 2 cases.	1990	2089001
life cycle of amblyospora indicola (microspora: amblyosporidae), a parasite of the mosquito culex sitiens and of apocyclops sp. copepods.	the life cycle of amblyospora indicola, a parasite of the mosquito culex sitiens, was revealed by field observations and laboratory infection experiments conducted in australia. in northern queensland, infected c. sitiens larvae were often found breeding in association with two cyclopoid copepods: apocyclops dengizicus and an undescribed species of the same genus. the latter species was found to be an intermediate copepod host of this microsporidium whereas a. dengizicus was not. one complete cy ...	1990	1972171
dermatophytoses as occupational dermatoses in industrialized countries. report on two cases from munich.	although interest in dermatophytoses as occupational dermatoses nowadays focuses on developing countries, pertinent cases are still also seen in industrialized countries. two recent cases from munich are reported in which trichophyton verrucosum had been acquired by a cattle farmer and microsporum canis by a veterinary surgeon from a pet cat.	1990	2141106
phylogeny of nannizzia incurvata, n. gypsea, n. fulva and n. otae by restriction enzyme analysis of mitochondrial dna.	sequence divergence among nannizzia incurvata, n. gypsea, n. fulva and n. otae was studied genetically using digestion profiles of mitochondrial dna with restriction enzymes, hae iii, hha i, hind iii and xba i. only n. fulva was subdivided into two types on restriction profiles. phylogenetic relationships suggest that 1) n. gypsea is more closely related to n. fulva than n. incurvata, 2) the phylogenetic distance between n. otae and the other three species is larger than the distances between th ...	1990	2089259
[experience in treating patients with microsporosis of the smooth skin with involvement of the lanugo hair].	seventy-four patients with smooth skin microsporosis with involvement of the lanugo were treated with a 10% quinosol solution in dimexid. the foci were smeared twice a day. resolution of the clinical manifestations and elimination of the fungi were achieved in 5-14 days, in 9.4 days on an average. this therapeutic method does not involve manual epilation and oral griseofulvin, no side effects were recorded.	1990	2111618
the sensitivity of dermatophytes to griseofulvin.	13 isolates of trichophyton violaceum and 7 microsporum langeroni from zambia and cameroon were tested in vitro for their sensitivity to griseofulvin. no strain was found resistant. all the 13 t. violaceum were inhibited by 4-8 micrograms/ml while 4 m. langeroni were inhibited by 0.5-1 microgram/ml.	1990	2260189
tinea capitis in awka local government area of anambra state.	between january and august 1984, a total of 1,555 primary school children aged 4-18 years were surveyed for tinea capitis in awka local government area of anambra state, nigeria. specimens for mycological investigations were aseptically collected from 300 children showing evidence of tinea capitis and processed by standard method. a total of 158 (10.2%) mycologically proven cases of tinea capitis were detected. prevalence of tinea capitis was higher in younger children (12.0%) aged 4-10 years th ...	1990	2268566
a survey of tinea capitis in primary school children in harare, zimbabwe.	a survey of the prevalence and appearance of tinea infections and associated dermatophytes in schools in harare is reported. of 704 children examined, 29% showed clinical evidence of tinea capitis; of these, 86% had mycological evidence of infection. dermatophytes were isolated from 69% of all the specimens. the most common was trichophyton violaceum (78% of the isolates), 9% of the dermatophytes were microsporum audouinii, and other isolates were t. mentagrophytes, t. yaoundei, m. gypseum and m ...	1990	2270008
keratinophilic fungi in bottom sediments of surface waters.	samples of bottom sediments from several artificial lakes, ponds, rivers and sewage in the silesia region of poland were examined for keratinophilic fungi. the intensity of growth on hair-bait, as well as the qualitative and quantitative distribution of keratomycetes in bottom sediments, depended on the level of sewage contamination of the water.	1990	2283586
synthesis and antimicrobial activities of some new tetrahydro-2h-1,3,5-thiadiazine-2-thione derivatives of ampicillin.	compounds having alpha-[dihydro-5-substituted 6-thioxo-2h- 1,3,5-thiadiazine-3(4h)-yl]benzylpenicillin structure were synthesized by the reaction of ampicillin trihydrate, formaldehyde and dithiocarbamic acid salts. the structures were evident from chemical and spectral analysis. the antimicrobial activities of the compounds were investigated against some gram-positive (staphylococcus aureus and streptococcus faecalis) and gram-negative (escherichia coli and pseudomonas aeruginosa) bacteria and ...	1990	2288482
fungi causing dermatophytosis in lagos, nigeria.	dermatophytes of the genera trichophyton, microsporum and epidermophyton were isolated from 162 (41%) of 395 patients with clinical manifestations of ringworm infection reporting at the lagos university teaching hospital, lagos, nigeria between january 1986 and december 1987. of the 162 strains of fungi isolated, 120 (74.1%) were microsporum species and 7 (4.3%) were epidermophyton floccosum. superficial mycosis was most prevalent on the skin (59.3%), followed by that of the hairs (27.2%). infec ...	1990	2364899
pathogenic fungi in soils of jabalpur, india.	results of a preliminary survey of pathogenic fungi in soils collected from forest, riverside and residential garbage soil in jabalpur, india, are reported. a total of 45 soils samples were examined, of which 39 (87%) were positive for fungi, 66 species of fungi classified in 35 genera were isolated: chrysosporium (78%), fusarium (69%), aspergillus (47%), microsporum (38%), gliocladium (16%), acremonium (11%), penicillium (11%), humicola (9%), scopulariopsis (7%), paecilomyces (7%), cladosporium ...	1990	2359416
[dermatomycoses observed at the dermatologic clinic, pavia university. 2) pathology of microsporum gypseum].	microsporum gypseum infections are 0.4% of 4900 suspected dermatomycoses examined with direct microscopic exam and culture on lactrimel medium or d.t.m. this geophilic dermatophyte was isolated in 20 cases (1.5% of all dermatophytes). more frequently m. gypseum caused tinea corporis (13 cases: 65%) and rarely tinea capitis (2 cases: 10%), tinea faciei (2 cases), tinea manus (2 cases) and tinea cruris (1 case). both sexes are equally affected. direct microscopic exam was negative in 2 cases. this ...	1990	2365400
[tinea capitis in adults. description of 3 cases].		1990	2365401
dermatophytosis of the scalp: incidence, immune response, and epidemiology.	tinea capitis remains a common infection among the pediatric population of north america. the 'gray patch' microsporum audouinii infections of the 1950's have been supplanted by the 'black dot' ringworm of trichophyton tonsurans. the clinical presentation of t. tonsurans infection is quite variable and may be related to specific host t-lymphocyte response. this dermatophytosis is most frequently incurred from contact with an infected child either directly or via a variety of fomites. current stu ...	1990	2183065
proton magnetic resonance study of cycloheximide-ribosome interactions.	cycloheximide-ribosome interactions from sensitive and resistant organisms were studied by proton magnetic resonance spectroscopic techniques. the two methyl resonances of cycloheximide upon interaction with ribosomes from saccharomyces cerevisiae showed preferential broadening. comparison of cycloheximide line broadening as effected by ribosomes from s. cerevisiae (sensitive) and microsporum canis (resistant) revealed that less cycloheximide is bound to the m. canis ribosomes. from the decrease ...	1990	2206134
detection of keratinolytic proteinase in skin tissues from guinea pigs infected with microsporum canis by an immunoperoxidase technique.	an immunoperoxidase technique was performed to detect keratinolytic proteinase (kpase) in sections of the skin taken from guinea pigs infected with microsporum canis and in cultured m. canis using polyclonal antisera to purified kpase. of tissue samples from guinea pigs infected with m. canis, all sections of erythematous lesions showed positive staining mainly in the horny layer and the hair follicles. positive depositions were seen only at the level of the outer and inner root sheaths of the h ...	1990	2288900
sterols of fungi responsible for superficial skin and nail infection.	two groups of fungi isolated from human skin and nail are the dermatophytes epidermophyton, microsporum and trichophyton species and the non-dermatophytes hendersonula toruloidea and scytalidium hyalinum. examination of the sterol composition of these fungi by gas chromatography-mass spectrometry (gc-ms) identified five new sterols from dermatophytes, namely cholesterol, campesterol, episterol, fecosterol and sitosterol. these sterols, with ergosterol and brassicasterol, were also identified fro ...	1990	2324703
tinea capitis in the netherlands (rotterdam area).	this retrospective study reviews the occurrence and treatment of various forms of tinea capitis at the out-patient clinic for dermatology and pediatric dermatology of the university hospital sophia/dijkzigt over the period 1977-1988. tinea capitis was diagnosed in 64 children. trichophyton violaceum was the pathogen most frequently isolated, with microsporum canis ranking second. the potassium hydroxide preparation was positive in 58% of the cases. four cases showed a positive potassium hydroxid ...	1990	2342520
[microsporum infection in patients treated at the dermatological clinic, medical academy, in gdańsk 1984-1988].	in the years 1984-1988 in the department of dermatology, m. a. in gdańsk 80 cases of microsporum mycoses were diagnosed. the cases were due to microsporum canis. among 80 cases of this mycosis we found 59 children aged from 2 to 15 years and 21 subjects aged over 15 years. in children the most cases were diagnosed in the age group 4-7 years. in 40 cases (50%). m. canis produced lesions of hairless skin and in 36 cases (45%) the scalp was involved.	1990	2217836
isolation of microsporum vanbreuseghemii from skin lesions of a dog.	routine examination of a 12-week-old labrador retriever revealed circular scaly lesions, with alopecia, on the lateral aspect of the left carpus and left upper eyelid. the geophilic fungus microsporum vanbreuseghemii was isolated from the lesions. topical treatment with chlorhexidine ointment resulted in resolution, with hair regrowth.	1990	2228771
[the dynamics of dermatomycetes in the bashkir assr in 1979-1987].	analysis of changes in dermatomycetes incidence in bashkiria in 1979-1987 has shown the predominance of zoophilic fungi in the latest 9 years, while the share of anthroponotic fungi has made up but 8.6%. the major agent of dermatophytosis in the republic was microsporum canis. the incidence of trichophyton verrucosum and trichophyton mentagrophytes v. gypzeune has grown of late, this necessitating the detection of new epidemiologic factors, contributing to dissemination of these mycoses and the ...	1990	2343671
review of animal mycoses in australia.	this review covers the available literature on the mycoses of animals in australia since the last review published in 1967. of the cutaneous infections, dermatophytoses have been recorded in a wide range of animals: cattle, horses, goats, pigs, sheep, cats, dogs, mice, guinea-pigs, rabbits, a lion, kangaroos, a camel, koalas and wallabies. these infections were caused by several species and varieties of the genera, microsporum and trichophyton. eight agents of ringworms have been recorded in the ...	1990	2233984
dermatophytes in healthy chilians.	to study the presence of dermatophytes in healthy persons, 1060 skin samples from the scalp, complexion, inguinal region and sole were taken from 265 healthy individuals who live in valdivia, chile. the carpet technique of mariat and tapia was used. the isolated dermatophytes were identified according to rebell and taplin. zoophilic dermatophytes were isolated in only 4.9% of the healthy individuals. microsporum canis was found in the scalp and inguinal area of children (1.5%). trichophyton ment ...	1990	2352545
isolations of dermatophyte from clinically normal scalps in m. canis infections using the hairbrush method.	the scalp hair of patients with dermatophytosis due to m. canis but without scalp lesions, and that of their family members without dermatophytosis were examined using the hairbrush method. the dermatophyte was detected in 93.8% of the scalps of those who lived in homes where cats were kept, and in 25% of those without cats. after the source of infection had been treated, the dermatophyte showed a gradually decreasing presence, finally disappearing altogether, so that no case of the disease on t ...	1990	2250690
wool-colonizing micro-organisms capable of utilizing wool-lipids and fatty acids as sole sources of carbon and energy.	two keratinolytic fungi, chrysosporium keratinophilum and malbranchea anamorph of uncinocarpus reesii, and another three wool-colonizing fungi not previously reported to be keratinolytic, aspergillus fumigatus, a. flavus and scopulariopsis candida, were isolated from soil samples baited with animal wool. these fungi were tested for their ability to utilize wool-lipids as sole source of carbon and energy. the lipid contents of wool of various animals ranged between 2 and 5%. the different lipid e ...	1990	2126788
in vitro activity of certain antibiotics against dermatophytes.	the in vitro effect of antibiotics i.e. hamycin, griseofulvin and mycostatin against microsporum gypseum and m. fulvum showed that hamycin was comparatively less inhibitory to m. fulvum. complete inhibition in mycelial growth and sporulation of these two dermatophytes was observed by mycostatin at its 1000 micrograms/ml conc. after 8 days. m. fulvum did not sporulate at higher concentration of griseofulvin. however, griseofulvin completely inhibited the sporulation in m. gypseum at all the conce ...	1990	2131330
in vitro nail invasion by pathogenic and non-pathogenic fungi under different culture conditions.	data from the literature suggest that the nutritional environment can modify major metabolic functions of fungi and possibly their aggressivity towards keratinous structures. trichophyton rubrum (tr), microsporum canis (mc), scopulariopsis brevicaulis (sb), aspergillus fumigatus (af) and penicillium spec. (p) were inoculated on media of different nutritional value, in presence of nail fragments. the activity of the fungi was evaluated at two and four weeks for intensity and depth of invasion of ...	1990	2103593
study of lipids in dermatophytes. i. the effect of ketoconazole on fatty acids of microsporum gypseum and its mutants.	there was studied the spectre of fatty acids and its changes induced by ketoconazole in the strain m. gypseum and its two mutants (uv-1, uv-2). the main saturate fatty acid in mg-155 and in both mutants is palmitic acid, the main unsaturate fatty acid is linoleic acid. in comparison with mg-155, uv-1 and uv-2 manifest a lower amount of stearic and oleic acids and a higher amount of stearic acid) in mg-155 and uv-1, an increase of saturate fatty acids is observed in uv-2. the unsaturate fatty aci ...	1990	2150281
[dermatophyte infections caused by microsporum canis and microsporum audouinii in the greifswald area].	report of serial diseases of dermatophytoses caused by m. canis (5 patients) and m. audouinii (9 patients). two cats and a dog were the infective source of m. canis-infection. m. audouinii-infection was stated in a children ward; here the infective source had not been detected. remarkable are the identical morphological lesions of tinea capitis resp. corporis and the affections of adults in the two groups of patients. griseofulvin therapy and additional veterinary hygienical treatment in case of ...	1990	2365106
[urban cycles of zoonotic mycoses].	based on their own results assembled during mycological examinations of 9958 subjects, 5496 animals and 648 specimens of non-animal substrates, and using data from the literature, the authors tried to formulate general laws concerning the prevalence of causal agents of mycoses with a zoonotic character which circulate steadily in urban areas: microsporum canis, m. persicolor, trichophyton mentagrophytes, m. equinum and t. equinum, t. verrucosum, some geophilic dermatophytes, cryptococcus neoform ...	1990	2150623
[dermatophytosis in a urban setting: prospective study of 135 cases].	during a period of one year all patients referred to the dermatology department with the diagnosis of dermatophytosis were studied to determine the incidence. etiology, and epidemiology of these infections in the northeast of madrid. we have evaluated the sensitivity and specificity of the direct examination with 10% koh with respect to the culture as well as the correlation between the clinical diagnosis and the result of the mycologic examination. the annual incidence was 8.4 cases per 10,000 ...	1990	2152479
itraconazole in the treatment of tinea capitis.	fifty patients with tinea capitis were treated with itraconazole, 25 to 100 mg/day, for 20 to 73 days in six countries. forty-seven patients (94%) responded clinically (healed or markedly improved) to therapy, of which 38 patients (76%) completely healed and 9 patients (18%) markedly improved. three patients (6%) failed therapy. forty-two patients were assessable for mycologic examination; 38 patients (93%) converted mycologically to negative and 4 patients (7%) remained positive for organisms. ...	1990	2170474
dermatomycoses and their etiology in the material of the dermatological department in lódź, poland.	in the period of 1982-1988 mycological examinations were carried out on 4,657 patients suspected of having dermatomycoses. in approximately 60% of patients infections were localized on the feet and hands and in approximately 30% other regions of the glabrous skin were involved. before treatment, 5,725 examinations were made. the diagnosis was confirmed mycologically in 30% of the cases, most often in tinea cruris (51%) and chronic paronychia (60%). in more than half of the cases the isolated fun ...	1990	2103597
effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs.	butenafine hydrochloride, n-4-tert-butylbenzyl-n-methyl-1-naphthalenemethylamine hydrochloride (butenafine), is a novel antifungal agent of the class of benzylamine derivatives. butenafine was investigated for its activity against guinea pig dermatophytosis caused by trichophyton mentagrophytes or microsporum canis in comparison with those of naftifine, tolnaftate, clotrimazole, and bifonazole. topical butenafine showed excellent efficacy against dermatophytosis when it was applied once daily, a ...	1990	2073116
cycloheximide enhances factor binding to the native 40s ribosomal subunit of microsporum canis.	native and derived ribosomal particles from the mycelial cells of microsporum canis grown in the presence and absence of cycloheximide were compared by cscl equilibrium density gradient centrifugation. since the buoyant densities of ribonucleoprotein complexes are dependent on the protein-rna ratio, they reflect the composition of these particles. the native monosomes from cells grown in the presence and absence of cycloheximide had a buoyant density of 1.585 g/cc. the native 60s subunits showed ...	1990	2099146
[the epidemiology of trichophytosis, microsporosis and favus in the armenian ssr].	mycoses of the hairy part of the head have been effectively treated in the two last decades in armenia. the number of trichophytosis patients has reduced from 32.7 per 100,000 in 1965 to 5.4 per 100,000 in 1987. the share of anthroponotic trichophytosis among all trichophytosis forms has reduced from 24.9 to 6.7 percent. chronic trichophytosis became quite rare among adult patients. favus has not been recorded in armenia since 1976. epidemic outbreaks of imported anthroponotic microsporosis were ...	1990	2147805
ultraviolet-mediated antimycotic activity of alpha-terthienyl on microsporum cookei.	alpha-terthienyl (alpha-t) in the presence of uv-a irradiation reduced the growth rate of microsporum cookei. in the dark, alpha-t accumulated in small diffuse vacuoles within the hyphae. after uv-a treatment, alpha-t caused damage to the membranes of the nucleus, mitochondria and endoplasmic reticulum. plasmolytic and autolytic changes occurred resulting in plasma membrane breakage and cell wall aberrations. uv-a activated alpha-t would appear to target membrane proteins.	1990	2093120
widespread dermatophyte infections that mimic collagen vascular disease.	this article reports the cases of two patients in whom a widespread dermatophyte infection mimicked the cutaneous lesions of their underlying collagen vascular disease. griseofulvin may be associated with an increased incidence of adverse cutaneous reactions in patients with systemic lupus erythematosus. one patient with systemic lupus erythematosus developed erythema multiforme after taking griseofulvin.	1990	2147700
differentiation of medically important isolates of bipolaris and exserohilum with exoantigens.	soluble culture extracts of bipolaris australiensis, b. hawaiiensis, b. spicifera, exserohilum longirostratum, e. mcginnisii, e. rostratum, and helminthosporium solani were used to prepare reference antisera in new zealand white rabbits. the absorbed reference antisera were tested by a microimmunodiffusion method against concentrated culture filtrates prepared from 115 environmental and clinical isolates of alternaria spp., bipolaris spp., curvularia spp., dactylaria sp., drechslera spp., embell ...	1990	2380387