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polysaccharide a of bacteroides fragilis: actions on dendritic cells and t cells.in a recent paper published in cell host & microbe, dasgupta et al. (2014) demonstrate that a component of the gut microbiota, bacteroides fragilis, induces il-10-producing regulatory t cells by driving tlr2-dependent plasmacytoid dendritic cell activation.201424766882
pneumocephalus in mixed aerobic and anaerobic (bacteroides fragilis) meningitis. 201424739868
design and in vitro evaluation of a novel poly(methacrylic acid)/metronidazole antibacterial nanogel as an oral dosage form.to overcome the undesirable side-effects of metronidazole (mtz), ethylene glycol dimethacrylate is used as the cross-linker, and a series of poly(methacrylic acid) (pmaa) nanogels were prepared to load the mtz. we investigated the morphology, size, in vitro release property in the simulated gastrointestinal medium, long-term antibacterial performance against bacteroides fragilis, cytotoxicity, stability and activity of this novel mtz/pmaa nanogel. the results indicate that the mtz/pmaa nanogel s ...201424727529
evaluation of bacteroides fragilis gb-124 bacteriophages as novel human-associated faecal indicators in the united states.phages infecting human-associated bacteroides fragilis (gb-124 phages) have been employed in the european union (eu) to identify human faecal pollution, but their utility for the united states was unclear. primary sewage samples were collected seasonally from seven wastewater treatment plants (wwtp) across the continental united states, and more time-intensive sampling was conducted at local wwtps. all samples were assayed for plaque-forming units (pfu) of gb-124 phages, somatic and frna-specifi ...201424725119
antibiotic resistance capability of cultured human colonic microbiota growing in a chemostat model.to evaluate the potential antibiotic resistance capability of cultured human colonic microbiota as a whole system when residual antibiotics enter the human intestine, the combination of viable cell counting and denaturing gradient gel electrophoresis (dgge) method was used to study effects of the enrofloxacin (enr) residue on the microbial diversity, antibiotic resistance, and anti-colonization capability in a human chemostat model. the results indicated that the enr enhanced the microbial antib ...201424715638
stat3 activation in murine colitis induced by enterotoxigenic bacteroides fragilis.enterotoxigenic bacteroides fragilis (etbf), a molecular subclass of the common human commensal, b. fragilis, has been associated with inflammatory bowel disease. etbf colitis is characterized by the activation of stat3 and a th17 immune response in the colonic mucosa. this study was designed to investigate the time course and cellular distribution of stat3 activation in etbf-colonized mice.201424704822
the reca operon: a novel stress response gene cluster in bacteroides fragilis.bacteroides fragilis, an opportunistic pathogen of humans, is a leading cause of bacteraemias and anaerobic abscesses which are often treated with metronidazole, a drug which damages dna. this study investigated the responses of the b. fragilis reca three gene operon to the stress experienced during metronidazole treatment and exposure to reactive oxygen species simulating those generated by the host immune system during infection. a transcriptionally regulated response was observed using quanti ...201424703997
influence of intrapartum antibiotic prophylaxis against group b streptococcus on the early newborn gut composition and evaluation of the anti-streptococcus activity of bifidobacterium strains.several factors are known to influence the early colonization of the gut in newborns. among them, the use of antibiotics on the mother during labor, referred to as intrapartum antibiotic prophylaxis (iap), has scarcely been investigated, although this practice is routinely used in group b streptococcus (gbs)-positive women. this work is therefore aimed at verifying whether iap can influence the main microbial groups of the newborn gut microbiota at an early stage of microbial establishment. fift ...201424687755
peptide sequence region that is essential for the interactions of the enterotoxigenic bacteroides fragilis metalloproteinase ii with e-cadherin.bacteroides fragilis is a valuable anaerobic commensal and an essential component of the gut microbiome in humans. the presence of a short pathogenicity island in the genome is predominantly associated with the enterotoxigenic strains of b. fragilis. metallopro-teinase ii (mpii) and fragilysin (fra) are the structurally related enzymes encoded by the pathogenicity island in the enterotoxigenic strains. accordingly, there is a significant overlap between the cleavage preferences of mpii and fra. ...201425964952
prevalence of extended spectrum beta-lactamase producing anaerobic bacteria in chronic periodontitis.due to the rampant use of antibiotics bacteria are acquiring resistance to penicillin group of drugs, which results in prescription failure in clinical practice. beta-lactamase producing organisms are not only more virulent they also cause surrounding bacteria to become resistant. hence, this study was undertaken to know the prevalence of extended spectrum beta-lactamase (esbl) producing anaerobic bacteria in chronic periodontitis.201425425816
distinct interactions with cellular e-cadherin of the two virulent metalloproteinases encoded by a bacteroides fragilis pathogenicity island.bacteroides fragilis causes the majority of gram-negative anaerobic infections in the humans. the presence of a short, 6-kb, pathogenicity island in the genome is linked to enterotoxigenic b. fragilis (etbf). the role of the enterotoxin in b. fragilis virulence, however, remains to be determined, as the majority of clinical isolates lack etbf genes and healthy individuals carry enterotoxin-positive b. fragilis. the island encodes secretory metalloproteinase ii (mpii) and one of three homologous ...201425411788
[isolation and identification of a non-enterotoxigenic strain of bacteroides fragilis from a healthy term infant].to identify a non-enterotoxigenic strain of bacteroides fragilis.201425399982
differential susceptibility of bacteria to mouse paneth cell α-defensins under anaerobic conditions.small intestinal paneth cells secrete α-defensin peptides, termed cryptdins (crps) in mice, into the intestinal lumen, where they confer immunity to oral infections and define the composition of the ileal microbiota. in these studies, facultative bacteria maintained under aerobic or anaerobic conditions displayed differential sensitivities to mouse α-defensins under in vitro assay conditions. regardless of oxygenation, crps 2 and 3 had robust and similar bactericidal activities against s. typhim ...201425383215
elucidating structural features of an entirely carbohydrate cancer vaccine construct employing circular dichroism and fluorescent labeling.the zwitterionic polysaccharide ps a1 from anaerobe bacteroides fragilis atcc 25285/nctc 9343 is known to elicit a t-cell-dependent, major histocompatibility complex class ii (mhcii) immune response through a correspondingly similar protein-antigen-based mechanism/pathway. the biological activity of ps a1 is known to arise from alternating charged motifs on adjacent monosaccharides comprising a tetrameric repeating oligomeric unit creating an alpha-helical secondary structure. however, we have l ...201425383162
comparison of the transport of bacteroides fragilis and escherichia coli within saturated sand packs.pathogens in groundwater accounted for ∼50% of waterborne disease outbreaks in the united states between 1971 and 2006. the fast and reliable detection of groundwater microbial contamination and the identification of the contamination sources are of critical importance to the protection of public health. recent studies suggested that fecal anaerobe bacteriodes spp. could be employed as an effective tool for surface water microbial source tracking (mst). the usefulness of bacteroides spp. for gro ...201425448721
use of maldi-tof/ms for routine detection of cfia gene-positive bacteroides fragilis strains. 201425216544
genome-wide evidence of positive selection in bacteroides fragilis.we used an evolutionary genomics approach to identify genes that are under lineage-specific positive selection in six species of the genus bacteroides, including three strains of pathogenic bacteroides fragilis. using orthomcl, we identified 1275 orthologous gene clusters present in all eight bacteroides genomes. a total of 52 genes were identified as under positive selection in the branch leading to the b. fragilis lineage, including a number of genes encoding cell surface proteins such as tonb ...201425215651
the capability of non-native strains of bacteroides bacteria to detect bacteriophages as faecal indicators in a tropical area.to evaluate the use of nonlocal, already-available strains of phages to indicate faecal contamination in thailand waters.201425207866
crystallization, preliminary x-ray crystallographic and cryo-electron microscopy analysis of a bifunctional enzyme fucokinase/l-fucose-1-p-guanylyltransferase from bacteroides fragilis.fucokinase/l-fucose-1-p-guanylyltransferase (fkp) is a bifunctional enzyme which converts l-fucose to fuc-1-p and thence to gdp-l-fucose through a salvage pathway. the molecular weights of full-length fkp (f-fkp) and c-terminally truncated fkp (c-fkp, residues 300-949) are 105.7 and 71.7 kda, respectively. in this study, both recombinant f-fkp and c-fkp were expressed and purified. size-exclusion chromatography experiments and analytical ultracentrifugation results showed that both f-fkp and c-f ...201425195892
activity of the investigational fluoroquinolone finafloxacin and seven other antimicrobial agents against 114 obligately anaerobic bacteria.the activity of finafloxacin against 73 strains of the bacteroides fragilis group, 10 other gram-negative anaerobic rods and 31 clostridium difficile strains was determined by the broth microdilution technique. the activity was compared with that of moxifloxacin, levofloxacin, ciprofloxacin, clindamycin, imipenem, piperacillin/tazobactam and metronidazole. mic(50/90) values (minimum inhibitory concentration, in μg/ml, at which 50% and 90% of the isolates tested are inhibited, respectively) for f ...201425264128
virulence factors and biofilm production by isolates of bacteroides fragilis recovered from dog intestinal tracts.bacteroides fragilis colonizes dog guts both as a commensal and as an opportunistic pathogen. this study aims to evaluate virulence factors of 13 b. fragilis strains isolated from dog intestinal tracts and their ability for biofilm formation. capsules were detected in all the evaluated strains. a total of 61.5% of all strains were biofilm producers. these attributes most likely play an important role in b. fragilis persistent colonization in the gut.201425242953
bacteria flying under the radar: linking a bacterial infection to colon carcinogenesis.the emergence of a link between helicobacter pylori infection and an increased risk of gastric cancer has raised an awareness of a possible link between colonic microbiota and colorectal cancer. pertubation of the colonic epithelium by toxin-producing strains of bacteroides fragilis may increase the risk of premalignant transdifferentiation. however, like h. pylori, b. fragilis exhibit an ability to modulate the normal host response to infection. we speculate this may be an underappreciated risk ...201425225573
metagenomic analysis of the gastric microbiota cultivable from a patient with gastritis concomitant with barrett's esophagus.barrett's esophagus is a distal metaplasia characterized by the transformation of squamous mucosa into columnar mucosa. this esophageal phenotype is a product not only of the chronic reflux of gastric acids, but also by microorganisms that colonize the oral cavity and stomach. two classes of microbiota can be identified in barrett's esophagus; microbiota type i is associated with the normal esophagus and type ii with an inflamed esophagus. the present study describes the gastric microbiota of a ...201425293992
evaluation of the in vitro activity of levornidazole, its metabolites and comparators against clinical anaerobic bacteria.this study evaluated the in vitro anti-anaerobic activity and spectrum of levornidazole, its metabolites and comparators against 375 clinical isolates of anaerobic bacteria, including gram-negative bacilli (181 strains), gram-negative cocci (11 strains), gram-positive bacilli (139 strains) and gram-positive cocci (44 strains), covering 34 species. minimum inhibitory concentrations (mics) of levornidazole, its five metabolites and three comparators against these anaerobic isolates were determined ...201425301712
anaerobic bacteria grow within candida albicans biofilms and induce biofilm formation in suspension cultures.the human microbiome contains diverse microorganisms, which share and compete for the same environmental niches. a major microbial growth form in the human body is the biofilm state, where tightly packed bacterial, archaeal, and fungal cells must cooperate and/or compete for resources in order to survive. we examined mixed biofilms composed of the major fungal species of the gut microbiome, candida albicans, and each of five prevalent bacterial gastrointestinal inhabitants: bacteroides fragilis, ...201425308076
an antimicrobial protein of the gut symbiont bacteroides fragilis with a macpf domain of host immune proteins.bacteroidales are the most abundant gram-negative bacteria of the human intestinal microbiota comprising more than half of the bacteria in many individuals. some of the factors that these bacteria use to establish and maintain themselves in this ecosystem are beginning to be identified. however, ecological competition, especially interference competition where one organism directly harms another, is largely unexplored. to begin to understand the relevance of this ecological principle as it appli ...201425339613
[bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between april 2010 and march 2011].bacteria isolated from surgical infections during the period from april 2010 to march 2011 were investigated in a multicenter study in japan, and the following results were obtained. in this series, 631 strains including 25 strains of candida spp. were isolated from 170 (81.7%) of 208 patients with surgical infections. four hundred and twenty two strains were isolated from primary infections, and 184 strains were isolated from surgical site infection. from primary infections, anaerobic gram-nega ...201425549405
understanding how commensal obligate anaerobic bacteria regulate immune functions in the large intestine.the human gastrointestinal tract is colonised by trillions of commensal bacteria, most of which are obligate anaerobes residing in the large intestine. appropriate bacterial colonisation is generally known to be critical for human health. in particular, the development and function of the immune system depends on microbial colonisation, and a regulated cross-talk between commensal bacteria, intestinal epithelial cells and immune cells is required to maintain mucosal immune homeostasis. this home ...201425545102
antimicrobial activity of traditional medicinal plants from ankober district, north shewa zone, amhara region, ethiopia.traditional medicinal plants have long been used in ethiopia to treat human and livestock ailments. despite a well-documented rich tradition of medicinal plant use in the country, their direct antimicrobial effects are still poorly known.201424392738
structural and functional diversity of metalloproteinases encoded by the bacteroides fragilis pathogenicity island.bacteroides fragilis causes the majority of anaerobic infections in humans. the presence of a pathogenicity island in the genome discriminates pathogenic and commensal b. fragilis strains. the island encodes metalloproteinase ii (mpii), a potential virulence protein, and one of three homologous fragilysin isozymes (fra; also termed b. fragilis toxin or bft). here, we report biochemical data on the structural-functional characteristics of the b. fragilis pathogenicity island proteases by reportin ...201424698179
distinct polymicrobial populations in a chronic foot ulcer with implications for diagnostics and anti-infective therapy.polymicrobial infections caused by combinations of different bacteria are being detected with an increasing frequency. the evidence of such complex infections is being revealed through the use of novel molecular and culture-independent methods. considerable progress has been made in the last decade regarding the diagnostic application of such molecular techniques. in particular, 16s rdna-based sequencing and even metagenomic analyses have been successfully used to study the microbial diversity i ...201424679105
diaryl-substituted azolylthioacetamides: inhibitor discovery of new delhi metallo-β-lactamase-1 (ndm-1).the emergence and spread of antibiotic-resistant pathogens is a global public health problem. metallo-β-lactamases (mβls) such as new delhi mβl-1 (ndm-1) are principle contributors to the emergence of resistance because of their ability to hydrolyze almost all known β-lactam antibiotics including penicillins, cephalosporins, and carbapenems. a clinical inhibitor of mbls has not yet been found. in this study we developed eighteen new diaryl-substituted azolylthioacetamides and found all of them t ...201425048031
structural analysis of arabinose-5-phosphate isomerase from bacteroides fragilis and functional implications.the crystal structure of arabinose-5-phosphate isomerase (api) from bacteroides fragilis (bfapi) was determined at 1.7 å resolution and was found to be a tetramer of a single-domain sugar isomerase (sis) with an endogenous ligand, cmp-kdo (cytidine 5'-monophosphate-3-deoxy-d-manno-oct-2-ulosonate), bound at the active site. api catalyzes the reversible isomerization of d-ribulose 5-phosphate to d-arabinose 5-phosphate in the first step of the kdo biosynthetic pathway. interestingly, the bound cm ...201425286848
distinct patterns of igg and iga against food and microbial antigens in serum and feces of patients with inflammatory bowel diseases.inflammatory bowel disease (ibd) is associated with a defective intestinal barrier and enhanced adaptive immune responses against commensal microbiota. immune responses against food antigens in ibd patients remain poorly defined.201425215528
functional identification of a galactosyltransferase critical to bacteroides fragilis capsular polysaccharide a biosynthesis.capsular polysaccharide a (cpsa), a polymer of a four-sugar repeating unit that coats the surface of the mammalian symbiont bacteroides fragilis, has therapeutic potential in animal models of multiple sclerosis and other autoinflammatory diseases. genetic studies have demonstrated that cpsa biosynthesis is dependent primarily on a single gene cluster within the b. fragilis genome. however, the precise functions of the individual glycosyltransferases encoded by this cluster have not been identifi ...201424997288
preferential packing of acidic glycosidases and proteases into bacteroides outer membrane vesicles.outer membrane vesicles (omv) are spherical membranous structures released from the outer membrane (om) of gram-negative bacteria. omv have been proposed to play several different roles during both pathogenesis and symbiosis. despite the fact that omv were described several decades ago, their biogenesis is a poorly characterized process. whether omv are produced by an active mechanism or by passive disintegration of the om is a still matter of controversy. bacteroides fragilis and bacteroides th ...201424618254
cephalosporinases associated with outer membrane vesicles released by bacteroides spp. protect gut pathogens and commensals against β-lactam antibiotics.to identify β-lactamase genes in gut commensal bacteroides species and to assess the impact of these enzymes, when carried by outer membrane vesicles (omvs), in protecting enteric pathogens and commensals.201425433011
an intestinal commensal symbiosis factor controls neuroinflammation via tlr2-mediated cd39 signalling.the mammalian immune system constitutively senses vast quantities of commensal bacteria and their products through pattern recognition receptors, yet excessive immune reactivity is prevented under homeostasis. the intestinal microbiome can influence host susceptibility to extra-intestinal autoimmune disorders. here we report that polysaccharide a (psa), a symbiosis factor for the human intestinal commensal bacteroides fragilis, protects against central nervous system demyelination and inflammati ...201425043484
plasmacytoid dendritic cells mediate anti-inflammatory responses to a gut commensal molecule via both innate and adaptive mechanisms.polysaccharide a (psa), the archetypical immunomodulatory molecule of the gut commensal bacteroides fragilis, induces regulatory t cells to secrete the anti-inflammatory cytokine interleukin-10 (il-10). the cellular mediators of psa's immunomodulatory properties are incompletely understood. in a mouse model of colitis, we find that psa requires both innate and adaptive immune mechanisms to generate protection. plasmacytoid dcs (pdcs) exposed to psa do not produce proinflammatory cytokines, but i ...201424721570
[the effect of group psychotherapy on reversion in schizophrenics. a comparative study]. 20134064148
[the effect of group psychotherapy on reversion in schizophrenics. a comparative study]. 20134064148
the effects of antipsoriatic treatment on cutaneous blood flow in psoriasis measured by 133xe washout method and laser doppler velocimetry.in 8 patients with psoriasis vulgaris, the cutaneous blood flow (cbf) was measured simultaneously in both involved and uninvolved psoriatic skin before (i.e., on the first day of hospitalization) and on the 3rd, 7th, 14th, and 28th days of treatment with tar. the 133xe washout method was used after epicutaneous labeling and compared to the laser doppler velocimetry (ldv) technique. control experiments were performed in 10 normal individuals. before treatment the mean cbf in involved psoriatic sk ...20133897394
comparative analysis of urinary corticosteroid and catecholamine levels in persons with different occupational training. 20133837738
[risk of losing a kidney]. 20133825626
[value of modeling of the clinical process in psychiatric research]. 20133688706
in vitro amikacin sensitivity testing. 20133744520
[status of lipid peroxidation in patients with silicosis]. 20133623157
erythromycin and cyclosporine. 20133740694
different mechanisms for activation of gene transcription by interferons alpha and gamma.treatment of hela cells with either recombinant interferon (rifn) alpha 2 or gamma elevated the level of mrna for 2',5'-oligo(a) synthetase and for a 56,000 mr protein. cycloheximide prevented the induction of these mrnas when rifn-gamma, but not rifn-alpha 2, was the inducer. this suggested that these rifns activate gene transcription by different mechanisms. the level of induced mrnas reached a maximum 8 or 12 hr, respectively, after addition of rifn-alpha 2 or rifn-gamma, and then slowly decr ...20133933177
different mechanisms for activation of gene transcription by interferons alpha and gamma.treatment of hela cells with either recombinant interferon (rifn) alpha 2 or gamma elevated the level of mrna for 2',5'-oligo(a) synthetase and for a 56,000 mr protein. cycloheximide prevented the induction of these mrnas when rifn-gamma, but not rifn-alpha 2, was the inducer. this suggested that these rifns activate gene transcription by different mechanisms. the level of induced mrnas reached a maximum 8 or 12 hr, respectively, after addition of rifn-alpha 2 or rifn-gamma, and then slowly decr ...20133933177
appearance of adenosine triphosphate in the perfusate from working frog heart.frog hearts (rana pipiens) were perfused in situ with ringer's solution and the perfusate tested on firefly extract for the presence of atp. at a normal perfusion pressure of 8 cm. h2o the rate of release of atp into the perfusate was 8.8 (+/- s.e.1.7) pmoles.min-1. when the workload was increased by raising the perfusion pressure to 12 cm. h2o the rate of release increased to 28.3 (+/- s.e.4.8) pmoles.min-1. the rate of release was found to be proportional to the amount of workload imposed upon ...20133877270
[monophasic menstrual cycle and its effect on periodontal tissues]. 20133870246
[acute juvenile mesotitis in ambulatory practice. ii. bacteriologic findings]. 20133815548
liver transplantation at the cleveland clinic. early results. 20133555885
[the use of occupational law in solving problems at obstetric-gynecologic facilities]. 20133811411
toward the elimination of guessing bias in landolt acuity testing.a subjective guessing bias has been claimed to be present in association with visual acuity testing using the classic circular landolt ring. a semiautomated visual test system has been described previously which uses an angular version of the broken ring. evidence is presented here which indicates that this version of the test object overcomes the problem of guessing bias and thus might prove to be not only a preferred "standard" or reference optotype but also an acceptable clinical optotype in ...20133777112
[mediastinal dislocation accentuated by initiation of pleural drainage]. 20133775925
barium embolisation during barium enema examination. 20133690174
the measurement of foot preference.foot preference has been given only superficial attention in studies of hemispheric lateralization, although it has potential utility for predicting hemispheric dominance. this paper reports the development of a reliable (alpha = 0.89) 11-item behavioral inventory of foot preference. since footedness and handedness are only partially related, both must be measured reliably to identify individuals who have a consistent right or left side preference. it has yet to be determined whether footedness ...20133683814
[effect of the loudness of a speech signal on the results of evaluation of the functional asymmetry of the brain]. 20133609581
self-instructional training: a commentary and state-of-the-art. 20133888941
self-instructional training: a commentary and state-of-the-art. 20133888941
ultrasound diagnosis in hepatorenal polycystic disease in children. 20133916543
ultrasound diagnosis in hepatorenal polycystic disease in children. 20133916543
[body weight changes in the aged].the paper reports on general medical experiences in a municipal territory concerning the weight changing of 129 women with an average age of 74,8 years. in a period of 5 years the investigated group showed an evidential trend to a weight decreasing.20134049930
[body weight changes in the aged].the paper reports on general medical experiences in a municipal territory concerning the weight changing of 129 women with an average age of 74,8 years. in a period of 5 years the investigated group showed an evidential trend to a weight decreasing.20134049930
inferior vena cava interruption. 20133874355
on the practice of medicine and on the culture and customs in japan--an impression of an american student. 20133837954
typhoid fever in young children. 20133836981
problems of modernization and occupational health in the people's republic of china. 20133832427
recent advances in experimental motion sickness. 20133892781
exercise thallium imaging in patients with diabetes mellitus. prognostic implications.we used exercise thallium 201 imaging in 123 patients with diabetes mellitus (77 men and 46 women, aged 56 +/- 8 years), 75% of whom had angina pectoris (typical or atypical). during exercise testing, 18 patients (15%) had angina pectoris, 28 (23%) had ischemic st changes, and 69 (56%) had abnormal thallium images. during follow-up (up to 36 months), there were 12 cardiac events; four patients died of cardiac causes and eight had nonfatal acute myocardial infarction. univariate and multivariate ...20133813750
when a student's client commits suicide. 20133851202
neurotoxicity caused by lithium-verapamil synergism. 20133793965
aluminium encephalopathy. 20133979053
view from the horizontal side of caring. 20133850407
[home life of the aged--psychological aspects].with increasing age the social and physical environment of elderly persons becomes increasingly focussed upon the home and its immediate surroundings, whilst life within the home ("wohnen") expands to take in a wider variety of activities. critical life events and transitions in old age often induce changes both in the way of life within the home and also in housing. the way of life of elderly people in the home ("alterswohnen") can be defined as the totality of goal-directed activities within t ...20133811468
[prevention of stress ulcers with cimetidine and ranitidine. comparative studies within the scope of cardiosurgical interventions].2 h2-receptor antagonists--cimetidine and ranitidine--were applied in our prospective randomized study in 100 cardio-surgical cases in order to test their therapeutical efficiency for the prophylaxis of bleedings of gastroduodenal stress-ulcers. during the phase of the intensive therapy of 2 days the patients of group a received t.i.d. 400 mg of cimetidine i.v. and those of group b twice a day 150 mg of ranitidine i.v. the following tests were realized: gastric acidity, plasma level, side-effect ...20133798932
[cutaneous delayed hypersensitivity to methyl hepatine carbonate in pulmonary tuberculosis]. 20133820872
[the "optura" system for the injection of thermo-plasticized gutta-percha into root canals]. 20133864811
restraint and seclusion. a standard and standard care plan. 20133848487
[procedures in fulminant courses of necrotizing enterocolitis].14/42 neonates suffering from n.e.c. developed the clinical stage iii (intestinal necrosis, septicemia) and/or iv (intestinal perforation, peritonitis) within 24-48 h ("fulminant" course). 2/14 deteriorated dramatically and died before operation. in 12/14 cases, the general condition could be improved and immediate laparotomy was performed (2/12 died). management and factors affecting prognosis are discussed. following surgery, there was no significant difference in survival rates between "fulmi ...20133807587
occasions for cyclosporine in the management of various renal transplant situations. 20133893107
chylothorax on technetium-99m antimony sulfide colloid scan. 20133772512
assessment of right and left heart interactions: application of the resistance ratio in chronic congestive heart failure. 20133779731
[computerized axial tomography of bladder hemangioma (apropos of a case)]. 20133739790
pancreatobiliary duct anatomy and alcoholic pancreatitis. 20133734371
[obstetrical nursing in comprehensive nursing]. 20134485384
reliability of anti-leu-m1 immunostaining in hodgkin's disease. 20133754715
[new guidelines for indications for balneotherapy--gynecologic diseases]. 20133719759
an alternative view of education for deaf children: part i. 20133716955
[fetal uropathies. diagnostic and therapeutic problems].based on the experience of 63 antenatal diagnosis of fetal uropathies, the authors discuss the diagnostic problems, practical implications of antenatal diagnosis and potential indications of in utero interventions. a correct diagnosis was established in 43 out of the 63 cases (70%). diagnostic problems were encountered in differentiating between multicystic dysplastic kidneys and uretero-pelvic junction obstruction, dilatation due to reflux or from obstruction and from the lack of visualisation ...20133912074
increased number of hypothalamic [3h] (+)-amphetamine binding sites in genetically obese (ob/ob) mice.in genetically obese (ob/ob) mice the development of obesity was correlated with the binding of [3h] (+)-amphetamine to the hypothalamus. in 39-day-old ob/ob mice, which had obtained a body weight greater than 150% of their lean littermates, hypothalamic [3h] (+)-amphetamine binding had increased by approximately 60% above levels of their lean littermates. this increased number of hypothalamic [3h] (+)-amphetamine binding sites appeared during the onset of obesity and then remained elevated foll ...20133703180
3-dehydroretinal in the eye of a bioluminescent squid, watasenia scintillans.3-dehydroretinal was found in the retina of a bioluminescent squid, watasenia scintillans. the possible vitamin a2-visual pigment was localized in the ventral part of the eye and its proportion was about 15% of the total visual pigment.20133716219
[health education in preventing diseases of the teeth and periodontium]. 20133845005
scanning electron microscopy of adenomatoid tumours.four adenomatoid tumours of the epididymis were embedded in paraffin wax, sectioned and the sectioned surfaces examined by scanning electron microscopy using the secondary electron mode. the solid faces of the sectioned neoplasms were damaged by the preparative technique but the depressed luminal surfaces of the tubules were well preserved and yielded useful information. large areas of luminal surface were examined and the presence and distribution of microvilli were noted. in addition, there wa ...20133697633
vitamin e deficiency and neurologic dysfunction in children. 20133702949
[remote results in the treatment of bimalleolar fractures]. 20133677877
biochemistry of muscle fatigue.fatigue--or decrease in force generation--is a reduction of simultaneously attached cross-bridges in the force generating state. two processes are necessary for the force generation: firstly ca++ release from the sarcoplasmic reticulum to the sarcoplasm and the binding of ca++ by the troponin molecule and secondly the turnover of myosin-actin cross-bridges. these processes require energy in at least three different atpase reactions and can consequently be inhibited when atp hydrolysis is decreas ...20133964254
biochemistry of muscle fatigue.fatigue--or decrease in force generation--is a reduction of simultaneously attached cross-bridges in the force generating state. two processes are necessary for the force generation: firstly ca++ release from the sarcoplasmic reticulum to the sarcoplasm and the binding of ca++ by the troponin molecule and secondly the turnover of myosin-actin cross-bridges. these processes require energy in at least three different atpase reactions and can consequently be inhibited when atp hydrolysis is decreas ...20133964254
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