Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| disk diffusion susceptibility testing of dermatophytes with allylamines. | allylamines are a newly developed group of drugs possessing a broad spectrum of activity against a wide range of fungi. with the advent of new antifungal drugs, susceptibility testing of fungi is receiving increased attention as important laboratory procedures for aiding in the selection of appropriate drug therapy. | 1994 | 8002146 |
| treatment of superficial mycoses in the tropics: whitfield's ointment versus clotrimazole. | in tropical primary health care, essential drugs should be safe, effective, and as inexpensive as possible. to treat the very common dermatophyte infections of the skin, one may use inexpensive whitfield's preparations, more expensive topical imidazole derivatives, or extremely expensive oral antifungals. because a cream base is felt to be more appropriate than an ointment in tropical conditions, we wanted to compare the effectiveness of whitfield's cream and a topical imidazole derivative in fi ... | 1994 | 8002148 |
| itraconazole versus griseofulvin in the treatment of tinea capitis: a double-blind randomized study in children. | tinea capitis is a fungal infection in which topical therapy is often unsuccessful. griseofulvin has been considered to be a first-line therapy. other antifungal agents are the azole derivatives. among these, itraconazole was compared with griseofulvin in children in a double-blind study. | 1994 | 8002149 |
| tinea capitis in lahore, pakistan. | the causative fungi of tinea capitis vary with geography and time. this study was planned to identify the etiologic agents and determine clinicoetiologic correlations of tinea capitis in lahore, pakistan. | 1994 | 8021080 |
| microsporum canis infection of the thumb-nail. | 1994 | 8033403 | |
| ecology and epidemiology of dermatophyte infections. | our knowledge of ecology and epidemiology of dermatophytes and the factors influencing their transmission has helped us understand better the natural history of dermatophytoses. it seems that the anthropophilic agents of scalp infection are being eradicated in developing nations. the exception is trichophyton tonsurans-related tinea capitis in north america. microsporum canis is a prevalent agent of tinea capitis in many regions of the world, and this could be related to close association of hum ... | 1994 | 8077503 |
| current therapy of dermatophytosis. | in the past dermatophytes were treated with topical agents or, in the case of more recalcitrant or extensive disease, with oral antifungals (griseofulvin or ketoconazole). topical therapies may be effective in many cases, but they have limitations. they may be viewed as inconvenient by the patient, thereby affecting compliance. therapy with early oral antifungals entails long treatment periods until complete cure is obtained. for ketoconazole rare but serious side effects can occur, particularly ... | 1994 | 8077504 |
| synthesis and structure-activity relationships of the novel homopropargylamine antimycotics. | analogues of the antimycotic allylamine terbinafine were prepared in which the naphthalene and the tert-butyl-acetylene moieties were preserved, but the spacer between these two groups was varied, and the antifungal activity of the new compounds was evaluated. all modifications of the original spacer such as reduction of the double bond, switching the position of the nitrogen atom, shortening, and elongation resulted in decreased potencies with one exception: compounds with the ch2nmech2ch2 grou ... | 1994 | 8126700 |
| tinea capitis in south wales--observations in change of causative fungi. | we report an observed change in the causative organisms in 45 consecutive cases of tinea capitis seen in the cardiff area over the last 9 years. direct microscopy using potassium hydroxide was positive in all but one case, but this was subsequently positive on culture. this retrospective analysis shows that more cases are being seen in our department, and that a higher proportion of cases are due to trichophyton violaceum whereas previously we would have expected the majority of cases to be due ... | 1994 | 7889666 |
| microsporum canis vaccine. | 1994 | 7852169 | |
| antidermatophytic activity of allylamine derivatives. | the allylamine derivatives are a new class of synthetic antifungal agents. the antidermatophytic activity of the two main compounds, naftifine and terbinafine were compared in vitro with those of ketoconazole and itraconazole by agar dilution. eighty eight clinical isolates of dematophytes comprising of microsporum canis (50), m. audouinii (5), trichophyton rubrum (6) t. mentagrophytes (5), t. violaceum (12), t. simii (5), t. verrucosum (1), t. soudanense (1), t. erinacie (1) and epidermophyton ... | 1994 | 7868170 |
| sds-page separation of dermatophyte antigens, and western immunoblotting in feline dermatophytosis. | water-soluble antigens liberated from the disrupted mycelium of nine dermatophytes (seven isolates of microsporum canis, one each of microsporum gypseum and trichophyton mentagrophytes) were compared by analytical slab sds-page. no substantial differences were observed between the protein bands of the m. canis isolates, but certain distinctive bands were apparent in the other two species examined. western immunoblotting using m. canis-derived antigens separated by sds-page was used to investigat ... | 1994 | 7777039 |
| mutants of dermatophytes resistant to ketoconazole. | authors describe the frequency and properties of mutants resistant to ketoconazole, obtained from the dermatophytes microsporum gypseum and trichophyton mentagrophytes. spontaneous mutants occurred with the frequency of 10(-9) to spore and nucleus. ultraviolet radiation increased the frequency of mutants by two numeric orders. the resistance level was relatively small in both types of mutants (rl within the range of 2-5). | 1994 | 7778498 |
| effect of ketoconazole on potassium pool, c-amp-release and ergosterol synthesis in resistant mutants of microsporum gypseum. | the effect of ketoconazole (kk) on chosen biochemical indexes was studied in three mutants of dermatophyte microsporum gypseum (mg-155 wild strain) resistant to kk. fungistatic concentration of kk added to liquid cultivate medium increases significantly ergosterol pool and nonsignificantly demethylation activity, potassium content, camp release in three days old mycelium of mutants when compared to the cultivation without kk. on the contrary, there is a significant suppression of ergosterol leve ... | 1994 | 7778499 |
| [the occurrence of keratinolytic fungi in the polluted environment of the labedy district in gliwice]. | this study was undertaken to find relationships between the degree of bacteriological contamination with qualitative composition of potentially pathogenic keratinolytic fungal population in soil, sediment and air samples from the labedy district in gliwice (poland). the examined soil samples were characterized by the predominance of botryotrichum piluliferum, chrysosporium anamorph of arthroderma curreyi, myceliophthora anamorph of ctenomyces serratus, chrysosporium pannicola and trichphyton aje ... | 1994 | 7792523 |
| possible role of calcium in phospholipid synthesis of microsporum gypseum. | the effect of calcium on lipid synthesis in microsporum gypseum was examined by growing these cells in calcium supplemented (1 mm to 10 mm) medium. maximum incorporation of [14c]acetate into total lipids and phospholipids was observed in cells grown with 6 mm calcium. this was probably due to a 3-fold increase in total calcium levels as incorporation of label was inhibited in total lipids (33%) and phospholipids (20.5%) in calcium-grown cells which were preincubated with the calcium specific che ... | 1994 | 7811720 |
| dicarboxylic acids affect the growth of dermatophytes in vitro. | azelaic acid is a dicarboxylic acid with known antimycotic activity. in this study we have used an agar dilution technique to test the effect of six other dicarboxylic acids (sebacic, undecanedioic, dodecanedioic, tridecanedioic, tetradecanedioic and hexadecanedioic acid, 10(-4)-10(-2) mol/l, ph 5.5) on in vitro growth of trichophyton (t.) rubrum, t. mentagrophytes and microsporum (m.) canis. furthermore, the fungicidal activity of 10(-2) mol/l undecanedioic and sebacic acid was tested using a t ... | 1994 | 7817668 |
| [microsporum langeronii dermatophytosis in a newborn infant contaminated in france]. | dermatophytosis due to microsporum langeronii was observed in a 21-day neonate born in bordeaux, france to a mother of west african origin. a typical misleading manifestations were: non alopecic squamation of the scalp with seborrhoea associated with circineous vesiculo-squamous lesions of the forehead. the source of the contamination was undoubtedly the mother who presented squamation without alopecia of the scalp. m. langeronii were observed in the scales and the hair. epidemiological search f ... | 1994 | 7832556 |
| phylogeny of dermatophytes and dimorphic fungi based on large subunit ribosomal rna sequence comparisons. | the phylogeny of dermatophytes and dimorphic fungi was considered using the large-subunit of ribosomal rna (25s rrna). aligned sequences of 595 nucleotides covering the two most divergent domains d1 and d2, permitted a comparison of phylogenetic relationships at different levels. the dimorphic species (onygenaceae) were significantly separated from dermatophytes (arthrodermataceae) and from a third group including geophilic or very weakly pathogenic species (onygenaceae and gymnoascaceae). on a ... | 1994 | 7844699 |
| microsporum canis infection in a 5-year-old boy: transmission from the interior of a second-hand car. | microsporum canis is one of the most common zoophilic dermatophytes. if transmitted to humans, inflammatory lesions may develop, e.g. on the scalp. m. canis was isolated from a 5-year-old boy living in a suburban area who suffered from a long-standing, mildly inflammatory lesion on the scalp that had been treated for several months with anti-eczematous regimens. there had been no contact with animals, e.g. cats or dogs, in the previous months, but the lesions had developed a few weeks after the ... | 1994 | 7845421 |
| polymerase chain reaction-based detection of dermatophyte dna with a fungus-specific primer system. | there is significant clinical interest in primers which are specific for fungi and do not hybridize to dna of other eukaryotes or prokaryotes. such primers would allow specific amplification of fungal dna from human tissue samples containing fungi. fungal identification to the species level could follow by direct sequencing or restriction analysis. several previously described primer systems cross-react with dna of plants and animals. we have designed a primer system that amplifies a fragment of ... | 1994 | 7845424 |
| [spread of a microsporum canis infection in an agricultural facility (case description)]. | in a combined pig production and fattening unit the weaned piglets on the flatdecks and some young fattening pigs were suffering from a microsporum canis-infection. besides the pigs the children of the farmer showed skin alterations. the infection was spread probably by the cats, which had access to the houses for sows and for sows with piglets. in cases of uncertain skin alterations, a mycologic etiology should be considered. | 1994 | 7717960 |
| antifungal activity of some 2,2':5',2"-terthiophene derivatives. | the dermatophyte microsporum cookei ajello was treated with nine new natural and synthetic 2,2':5',2"-terthiophenes to determine their possible antifungal activity. in the dark the thiophenes were inactive, while when photoactivated with uv-a they induced a remarkable reduction in the growth rate of the fungus. the only exception was (e)-n-(2-methylpropyl)-3-(2,2':5',2"-terthien-5-yl)-propenamide , which was not fungistatic even at the highest dose tested (24 microm). the more active compounds w ... | 1994 | 7746300 |
| improved sensitivity in the diagnosis of dermatophytosis by fluorescence microscopy with calcafluor white. | 1994 | 7516594 | |
| screening of different keratin baits for isolation of keratinophilic fungi. | twenty different keratin-rich substrates were screened as keratin baits for isolation of keratinophilic fungi from different soil sample of chhindwara district, india. fungi easily formed colonies on different baits. however, hair, feathers and horns were found to be more suitable than nails, fish fins and fish scales. | 1994 | 7537862 |
| successful treatment of griseofulvin-resistant tinea capitis in infants. | we report on three siblings, children of a farmer, aged 3-8 years, suffering from tinea capitis due to microsporum canis. initially, the infection was treated systemically with griseofulvin as well as externally for 5 months without success. therapy was changed to itraconazole 33 mg per day orally. laboratory investigations followed every 4-6 weeks. dependent on the dose per kg body weight the children were cured clinically after 2-5 months and microbiologically after 5-8 months. thus, itraconaz ... | 1994 | 7659136 |
| [interspecific outbreaks of dermatomycoses +caused by microsporum canis and microsporum gypseum]. | dermatomycosis in domestic animals are important zoonosis in view of the fact that they maintain close contact with human beings. seven ringworm outbreaks are here described, one of m. gypseum involving a cat and a women and the remainder of m. canis involving 20 human beings (adults, young people and children), 5 dogs, 16 cats and a gibbon-monkey (hylobates lar). | 1994 | 7660034 |
| development of an experimental model of microsporum canis infection in cats. | an experimental infection model was developed for reliable induction of microsporum canis skin infections in cats, using a defined number of macroconidia harvested from the fungus in culture. the strain of m. canis used produced highly fluorescent hairs under ultraviolet illumination. kittens 8 to 9 weeks of age (n = 6) received 10(5) macroconidia applied topically to a closely-shaved area of skin. sites were dressed with an occlusive bandage for 3 days, then grooming was restricted for an addit ... | 1994 | 9133054 |
| immunogenicity in guinea-pigs of a crude ribosomal fraction from microsporum canis. | the immunogenicity of a crude ribosomal fraction (crf) extracted from microsporum canis was tested by assessing protection of vaccinated guinea-pigs (gp) against a challenge with the dermatophyte. stimulation of the humoral as well as the cellular immune systems of these animals was evaluated by elisa and the lymphocyte stimulation tests, respectively. in addition, the immune response elicited by the m. canis crf was examined for cross-reactivity towards trichophyton verrucosum antigen. the dura ... | 1994 | 8147094 |
| gypsetin, a new inhibitor of acyl-coa:cholesterol acyltransferase produced by nannizzia gypsea var. incurvata ifo 9228. i. fermentation, isolation, physico-chemical properties and biological activity. | a novel inhibitor of acyl-coa:cholesterol acyltransferase (acat), designated gypsetin, was isolated from the cultured broth of nannizzia gypsea var. incurvata ifo 9228 by solvent extraction, silica gel chromatography and crystallization. gypsetin inhibited rat liver microsomal acat activity competitively with respect to the substrate oleoyl-coa with an apparent ki value of 5.5 microm. in cultured macrophage j774 cells incubated with oxidized low density lipoprotein, gypsetin inhibited cholestery ... | 1994 | 8150711 |
| gypsetin, a new inhibitor of acyl-coa: cholesterol acyltransferase produced by nannizzia gypsea var. incurvata ifo 9228. ii. structure determination. | the elucidation of the structure of gypsetin, a new inhibitor of acyl-coa: cholesterol acyltransferase, is described in this paper. by spectroscopic and x-ray crystallographic analyses, the structure of gypsetin has been determined to be 8a,16a-dihydroxy-5a,13a-bis[1,1-dimethylallyl]-[1]benzazolidine [3''' 2''':4'',5'']azolidino[1'',2'':4',5'][1,4]perhydrodiazin[1', 2':1, 5]azolidino[2,3-b]-[1]benzazolidine-7,15-dione. | 1994 | 8150712 |
| an evaluation of the resistance to microsporum canis on the basis of the guinea pig. | the purpose of the work was to assess the immune response of guinea pigs after the experimental infection with microsporum canis, and after immunization with a specific live vaccine. the guinea pigs after the recovery from infection showed a delayed type of hypersensitivity and in addition, 30 per cent of the animals were characterized by the presence of immediate hypersensitivity reactions. all the animals were resistant to reinfection with m. canis and to some extent to trichophyton verrucosum ... | 1994 | 8891170 |
| in vitro antifungal activity of essential oils against some isolates of microsporum canis and microsporum gypseum. | 1994 | 8202570 | |
| [uncommon caseous maxillary sinusitis of dental origin caused by microsporum canis]. | the authors report an uncommon case of maxillary sinusitis due to microsporum canis. to their knowledge this is the first observation in which a zoophilic dermatophytic fungus which grows usually on keratin has been isolated in a dental maxillary sinusitis in human. this observation makes it possible to discuss nosologic and diagnostic features of dental caseous sinusitis and fungal sinusitis which are often or too often called aspergillosis sinusitis. | 1993 | 8210096 |
| epidemiological and diagnostic features of canine and feline dermatophytosis in the united kingdom from 1956 to 1991. | between 1956 and 1991, 8349 samples from dogs and cats were received for investigation of suspected dermatophytosis, and 1368 (16 per cent) yielded positive cultures. cats had a significantly higher proportion of positive cultures (26 per cent) than dogs (10 per cent), and of these microsporum canis accounted for 92 per cent in cats and 65 per cent in dogs. the other isolates were diverse but mainly sylvatic dermatophytes, and m gypseum was isolated on only four occasions. different breeds of do ... | 1993 | 8212483 |
| increasing importance of trichophyton tonsurans in childhood tinea in new south wales. the pattern of childhood tinea in new south wales, australia 1979-1988: the emergence of trichophyton tonsurans as an important pathogen in tinea capitis in white children. | a retrospective study was undertaken of 192 cases of culture proven tinea capitis occurring between 1979 and 1988 in a predominantly white population of children in new south wales (nsw). the aim of the study was to identify whether trichophyton tonsurans was increasing in importance in the causation of this condition in australia as it was in many other parts of the world. the results of our study were compared with those of earlier australian studies. our study demonstrated that trichophyton t ... | 1993 | 8240189 |
| the presence of dermatophytes in the environment and on healthy looking skin: their significance as a cause of disease in japan. | 1993 | 8242801 | |
| tinea capitis in trinidad. | characteristics of clinically diagnosed cases of tinea capitis from trinidad are described. tinea capitis comprised 29.5% of all dermatophytoses seen at one general hospital out-patient dermatology clinic during a one-year period. males were more often affected than females and there was a predominance of patients of african descent. among the dermatophytes cultured trichophyton tonsurans was the most prevalent (52.9%), followed by microsporum canis (20.0%) and m. audouinii (18.6%). less frequen ... | 1993 | 8254711 |
| immunohistological characterization of the cellular infiltrate in dermatophytosis. | the local cell composition of skin infections caused by trichophyton rubrum (13 cases) and microsporum canis (2 cases) was examined using monoclonal antibodies and the abc immunoperoxidase technique. the number of langerhans cells increased both in the epithelium and in the dermis of the mycotic area. apart from these, only t cells were found in the dermis, among which helper cells were predominant. the helper/suppressor ratio showed variations depending upon the pathogen. | 1993 | 8264718 |
| fungitoxicity of essential oils against dermatophytes. | sixteen essential oils were screened in vitro for their fungitoxicity against the two dermatophytes trichophyton rubrum and microsporum gypseum. five oils (from artemisia nelagrica, caesulia axillaris, chenopodium ambrosioides, cymbopogon citratus and mentha arvensis) showed strong activity and were assessed for their fungitoxicity against eight other dermatophytes as well as against aspergillus fumigatus and cladosporium trichoides. these five essential oils by formulation of ointments were abl ... | 1993 | 8264720 |
| dermatophytosis of children in kuwait: a prospective survey. | tinea capitis in children is widely reported, whereas there have been only isolated reports on involvement of sites other than the scalp. the purpose of this study was to examine the epidemiological features and treatment responses of dermatophytosis of children in kuwait. | 1993 | 8270336 |
| dermatophyte pseudomycetoma: a case report. | a 25-year-old man presented with several prominent subcutaneous masses in the occipital region of the scalp. he had a long history of tinea capitis and tinea corporis infection. histopathology of the occipital lesions showed mycelial aggregates in the deep dermis and subcutis. cultures of the excised material and superficial scales grew a fungus identified as microsporum ferrugineum. we propose the term 'dermatophyte pseudomycetoma' to describe this distinctive mycosis. | 1993 | 8286261 |
| humoral immune responses in cats with dermatophytosis. | the igg and igm classes of antibodies to a water-soluble antigen preparation derived from microsporum canis were determined by elisa in the sera of 79 cats with dermatophytosis confirmed by results of fungal culture, and of 46 specific-pathogen-free-derived, barrier-maintained cats with no previous exposure to dermatophytes. of the 79 cats with dermatophytosis, the species isolated were: m canis from 72, m gypseum from 6, and trichophyton mentagrophytes from 1. concentrations of soluble m canis ... | 1993 | 8291765 |
| [reported frequency of dermatophytes in cats and dogs in austria]. | during four years (1988-1991) 384 skin scrapings and hair samples obtained from cats and 636 samples obtained from dogs in austria were examined routinely for dermatophytes. in cats dermatophytes were isolated or found positive in unstained koh preparation in 50.3% of the samples. 90.7% of these cats were proved to be infected with microsporum canis. trichophyton mentagrophytes was isolated in 5.2% and trichophyton spp. in 2.1% of the positive samples. in dogs dermatophytes were isolated from 12 ... | 1993 | 8306866 |
| [evaluation of susceptibility of dermatophytes to antifungal drugs]. | a serial dilution and a disc method were used for evaluation of susceptibility of 50 dermatophyte strains belonging to the species trichophyton rubrum, trichophyton mentagrophytes, microsporum canis and epidermophyton floccosum. following drugs were investigated: griseofulvin, pimaricin, clotrimoxazole, miconazole, ketoconazole, biphonazole and naftifin. application of two methods of testing resulted in high convergence of determinations. naftifin was most effective and pimaricin least active. a ... | 1993 | 8309309 |
| in vitro susceptibility testing of antimycotics. | 1993 | 8318086 | |
| [causal agents of tinea of the scalp in the region of butare (rwanda)]. | one hundred children with clinical symptoms of tinea capitis have been examined. the samples were inoculated on sabouraud medium and incubated at 25 degrees c. in 65 of 100 cultured samples at least one dermatophyte was isolated. in 42 cases trichophyton violaceum and in 26 cases microsporon langeroni was grown. the cultures of three patients resulted in the mixed growth of trichophyton violaceum and microsporon langeroni. determination of the type of tinea capitis on clinical symptoms alone is ... | 1993 | 8323410 |
| [enantioselective synthesis and antifungal activity of optically active econazole and miconazole]. | in an effort to investigate the relationship between stereochemistry and antifungal activity of the antimycotic agents, optically active econazole and miconazole were first enantioselectively synthesized. the key step was the enantioselective reduction of 2-chloro-1-(2,4-dichlorophenyl) ethanone catalyzed by chiral oxazaborolidine. preliminary biological tests showed that (r)-(-)-econazole and (r)-(-)-miconazole were more active than the (s)-isomer and racemates against common pathogenic fungi s ... | 1993 | 8328265 |
| [pets as permanent excretors of zoonoses pathogens]. | when scrutinizing zoonoses with regard to risks for human beings, the spectrum of pathogens with dogs, cats and birds leading to persistent infections and consequently to the fact that the animals become carriers and permanent excretors is relatively small. most of the zoonoses cause clinical symptoms and will be taken care of correspondingly. with regard to dogs there is a multitude of persistent infections that are transferred from the pet to the human being and vice versa. in reality, however ... | 1993 | 8333899 |
| in vitro susceptibility of dermatophytes to antifungal drugs: a comparison of two methods. | there is an evidence that some fungal strains are resistant to certain antimycotic drugs with resulting therapeutic failures. unlike testing of antibacterial agents, the activity of these drugs against the given fungal strains is not tested routinely. the paper presented is an approach to such a procedure. | 1993 | 8340195 |
| langerhans cell histiocytosis and dermatophytosis. | langerhans cell histiocytosis (lch) is regarded as a disorder of histiocytic cell proliferation of the langerhans type, probably resulting from altered immunoregulation. cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, scaling and erythema may also be confused with tinea capitis. we describe four patients who had lch and documented dermatophyte infection versus colonization of the scalp. fungal cult ... | 1993 | 8340510 |
| [identification of dermatophytes as possible agents in clinically and microbiologically diagnosed dermatophytosis]. | in this study we have investigated the distribution of dermatophyte species clinically and microbiologically on 110 patients with dermatophytosis. the distribution of the dermatophytes according to the localization sites are: tinea capitis 13 (11.8%), t. corporis 12 (10.9%), t. inguinalis 22 (20%), t. pedis et manum 47 (42.7%), t. unguinum 16 (14.5%). the species of dermatophytes which have been cultured were, trichophyton rubrum 32 (29%), t. mentagrophytes 32 (29%), t. schoenleini 4 (3.6%), t. ... | 1993 | 8361407 |
| tinea corporis bullosa. | the paper reports a case of tinea corporis bullosa in a 63-year-old woman. near the classical annular lesions on the anterior surface of the left leg, the patient presented frank bullous lesions. serous fluid from the bulla yielded microsporum canis, the first report of the association of this fungus with bullous lesions in tinea corporis. the patient was investigated with routine examinations and immunological studies which showed an intense inflammatory process much greater than in usual cases ... | 1993 | 8366877 |
| fungal skin infections in a paediatric dermatology clinic. | a diagnosis of fungal infection was established in 8.6% of patients who attended the dermatology clinic at the lady ridgeway hospital, colombo over a one year period. only 4.3% were confirmed in the laboratory. the agreement between clinical and laboratory diagnosis was 96.6% for patients with typical clinical features, but only 26.4% for patients who did not have the classical appearance. both direct microscopy and culture are required to determine the causative agent, although the majority (92 ... | 1993 | 8370091 |
| further studies on the influence of aminophylline on lipids of microsporum gypseum. | aminophylline added to the growth medium of microsporum gypseum for varying periods exhibited varied effects on lipid synthesis. a decreased incorporation of [14c]acetate into both lipids and phospholipids was initially observed which showed increase after 24 hr of incubation. short-time exposure of aminophylline also resulted in decreased activity of glycerol-3-phosphate acyltransferase, the key enzyme of lipid synthesis, which, however, got stimulated on longer incubation, supporting the decre ... | 1993 | 8389728 |
| oral itraconazole versus topical bifonazole treatment in experimental dermatophytosis. | guinea pigs, infected with either trichophyton mentagrophytes or microsporum canis, were treated orally or topically with azole antifungals daily for two weeks. fungi located in the stratum corneum were affected similarly by both treatment schedules, showing typical cell wall changes after azole exposure and necrosis of internal organelles. fungi located in the hair sheaths were affected only by the oral treatment, which not only prevented invasion of the inner hair structures and inflammatory r ... | 1993 | 8396203 |
| superficial fungal infections in newborns. | 1993 | 8406721 | |
| epidemiology of the dermatophytoses in the florence area of italy: 1985-1990. trichophyton mentagrophytes, epidermophyton floccosum and microsporum gypseum infections. | between 1985 and 1990 we observed 2085 cases of dermatophytoses in the florence area of italy. trichophyton rubrum and microsporum canis were the major etiological agents. 126 cases of dermatophytoses observed during this period were caused by trichophyton mentagrophytes. most of the patients came from rural areas or they kept pets. epidermophyton floccosum ranked fourth in frequency (95 cases). the patients were adults and mainly males, most of whom engaged in sports or lived in group environme ... | 1993 | 8413498 |
| tinea capitis in saudi arabia. | tinea capitis is a dermatophyte infection of the scalp, eyebrows, and eyelashes caused by species of microsporum and trichophyton. the purpose of this study was to discover the incidence and causal agents of tinea capitis in saudi arabia. | 1993 | 8425800 |
| the ringworm riddle: an outbreak of microsporum canis in the nursery. | tinea capitis, the most common fungal infection in children, is rare in neonates. we report six patients in a level ii intermediate care nursery who developed nosocomial dermatophyte infections caused by microsporum canis. the investigation, which led to the identification of a nurse as the common source, is described. the nurse had an indolent infection with m. canis. human to human transmission is exceedingly rare for m. canis. the literature regarding neonatal dermatophyte infections is discu ... | 1993 | 8426773 |
| ultrastructure of trichophyton violaceum. | the ultrastructure of different fungi have been described in recent literature; however, few reports have concerned dermatophytes. | 1993 | 8440569 |
| microsporum canis infection in sheep. | 1993 | 8488650 | |
| humoral and cellular immune responses to microsporum canis in naturally occurring feline dermatophytosis. | peripheral blood lymphocytes isolated from cattery cats which were culture positive for microsporum canis, or from cats which had recovered from m. canis infection, showed a significantly greater mean in vitro blastogenic response to m. canis antigen than lymphocytes from uninfected cats. mean lymphocyte reactivity to concanavalin a was higher in cats which had recovered from infection than in either culture positive or uninfected cats, whereas reactivity to phytohemagglutinin was highest in the ... | 1993 | 8509949 |
| purification, characterization, and lytic activity against naegleria fowleri of two amoebicins produced by bacillus licheniformis a12. | bacillus licheniformis a12 produces two amoebolytic substances (amoebicins a12-a and a12-b) in liquid media during sporulation. both substances have been purified and characterized. they are heat- and protease-resistant peptides containing aspartic acid, glutamic acid, serine, proline, and tyrosine in a molar ratio of 5:2:2:2:2. no fatty acids or carbohydrates have been detected. their molecular weight is 1,430. purified amoebicins a12-a and a12-b exhibit amoebolytic action against naegleria fow ... | 1993 | 8517742 |
| [analysis of microsporum dermatomycoses in szczecin, its terrain and regions in the years 1985-1988]. | the retrospective analysis of m. canis infections in szczecin and its region, and the comparison with other dermatomycoses are presented. the study comprised two groups of patients: 450 patients diagnosed between january 1985--december 1988 to have microsporum infections, and 449 patients with the diagnosis of dermatomycosis made between january 1986--december 1988. data collected in form of patients personal cards were subsequently analysed with the use of standard statistical methods. most of ... | 1993 | 8154613 |
| dermatophytes and other associated fungi isolated from ringworm lesions of camels. | among 75 camels showing skin lesions, 48% were positive for fungal infection. the younger individuals were more susceptible to this infection. sixteen species belonging to nine genera of keratinophilic and cycloheximide-resistant fungi were recovered from diseased camels. trichophyton, microsporum and chrysosporium were the most common genera. t. verrucosum appeared to be the main cause of ringworm in small camels while t. mentagrophytes infected older ones. camel skin presents a suitable habita ... | 1993 | 8150398 |
| isolation and physico-chemical characterization of an antifungal and antibacterial peptide produced by bacillus licheniformis a12. | an antifungal substance named peptide a12-c has been purified to homogeneity from supernatants of sporulated cultures of bacillus licheniformis a12. it consists of a 0.77-kda hydrophilic peptide containing two residues of glu and one of arg, ala, pro, tyr and orn. no fatty acids, phosphorus or carbohydrates have been detected. peptide a12-c is active on several fungi (microsporum canis cect 2797, mucor mucedo cect 2653, m. plumbeus (ccm f 443, sporothrix schenckii cect 2799 and trichophyton ment ... | 1993 | 7763922 |
| atypical features of tinea in newborns. | 1993 | 7848375 | |
| antifungal activities of crude extracts of mitracarpus villosus (rubiaceae). | extracts of mitracarpus villosus leaves and inflorescences were investigated individually for in vitro antifungal activities by agar-diffusion and tube-dilution techniques. ethanolic extracts produced definite antifungal activities against trichophyton rubrum, microsporum gypseum, candida albicans, aspergillus niger and fusarium solani. the aqueous extracts and the glycerol vehicle control did not inhibit any of the fungi tested. the zones of inhibition produced by the ethanol extracts ranged fr ... | 1993 | 8133654 |
| epidemiological study of tinea capitis in puerto rico. | two separate studies were carried out to determine the dermatophytes responsible for tinea capitis in puerto rico. a retrospective study to determine those agents during the period between 1979 and 1989 revealed a total of 36 mycologically positive cases. the causative organisms consisted of the following species: m. canis, 14 cases (38.9%); t. mentagrophytes, 7 cases (19.4%); t. rubrum, 7 cases (19.4%); m. gypseum, 5 cases (13.9%); and t. tonsurans, t. verrucosum, unclassified microsporum speci ... | 1993 | 8140209 |
| [incidence of various etiologic agents of superficial mycosis]. | in a retrospective review of laboratory records at the department of mycology, national institute of microbiology "dr. carlos g. malbrán", during the period june 1989-july 1991, 1225 putatively immunocompetent cases of superficial mycoses were identified. ninety five percent of these patients were adults and 5% children. among the total cases, dermatomycoses were caused, 67.6% by dermatophytes, 25.9% by yeasts, 5.9% by malassezia furfur. and 0.5% by other fungi, as proven by the isolation of the ... | 1993 | 8140245 |
| diagnosis of favus (avian dermatophytosis) in oriental breed chickens. | chickens of various oriental breeds (shamo and aseel) and crossbreeds in california's central valley were observed to have an unusual skin condition and feather loss. the appearance of white plaques on the comb, face, and/or ear lobes was followed by feather loss starting at the caudal base of the comb and progressing down the neck. although the cocks were affected first, the condition spread to the hens paired with those cocks. the birds showed no other signs of illness. the affected areas were ... | 1993 | 8141747 |
| influence of cyclic amp on the biosynthesis of phosphatidylcholine in microsporum gypseum. | the influence of intracellular camp on phosphatidylcholine biosynthesis in microsporum gypseum has been examined using radiolabelled precursors. the incorporation of labelled choline, methionine and ethanolamine into total lipids, phospholipids and choline containing phospholipids increased in aminophylline and decreased in atropine grown cells as a result of rise and fall in camp levels in these cells. the enhanced uptake of labelled methionine and ethanolamine in comparison to labelled choline ... | 1993 | 8144178 |
| plants used in guatemala for the treatment of dermatophytic infections. 2. evaluation of antifungal activity of seven american plants. | from 52 plants screened for antifungal activity, 26 (50%) were active against dermatophytes. this paper reports further evaluation of seven american plants against four pathogenic fungi (aspergillus flavus, epidermophyton floccosum, microsporum gypseum and trichophyton rubrum), the part showing most activity, the best solvent and, in three cases, the minimal inhibitory concentration (mic) against the fungus in pure culture. antifungal activity was confirmed in all of the plants, but not all part ... | 1993 | 8145577 |
| microsporum canis scalp ringworm: its primary or secondary ectothrix character. | this study supports the view that, in cases of tinea capitis due to a microsporum canis infection, ectothrix arthroconidium formation is extrapilary and arises from intrapilary hyphae. the hyphae of m. canis perforate and digest the hair cuticle to alter its appearance from a normally identifiable structure of imbricated cells with a distal free border, to a grossly altered and pathological layer. conidium production mainly takes place outside the hair shaft and forms thick clusters between the ... | 1993 | 8108682 |
| [gum-like exudate from laguncularia racemosa (white mangrove) as culture media for fungi]. | morphological studies of eight species of fungus: aspergillus flavus microsporum canis, epidermophyton floccosum, curvularia lunata, cladosporium carrionii, natrassia mangífera (edo. scytalidium), sporotrix schenckii y rhizophus oligosporus, which belong to families mucedinaceae, dematiaceae and mucoraceae have been carried out in support medium based in gum exudate from laguncularia racemosa (mangle blanco). this native polimer contains galactose, arabinose, rhamnose, uronic acid and proteins. ... | 1993 | 8123711 |
| [synthesis and antifungal activity of 1-(2-[(4-substituted-phenyl) methoxy]-2-(substituted-phenyl) ethyl)-1h-azoles]. | twenty nine 1-(2-[(4-substituted-phenyl) methoxy]-2-(substituted-phenyl) ethyl)-1h-azoles were synthesized for searching of more potent and less toxic antimycotic agents. nine of the title compounds are first reported. results of preliminary biological tests showed that most of the title compounds exhibited activity against the common pathogenic fungi such as candida albicans, microsporum bodin, trichophyton gypsum, epidermophyton floccosum, trichophyton violaceum, microsporum ferrugincum, trich ... | 1993 | 8010011 |
| dermatophytes and dermatophytoses in the milan area between 1970 and 1989. | between 1970 and 1989 we examined 13,019 patients with dermatophytoses in the milan area, northern italy. the results obtained during the 1980-89 period were compared with those obtained in the years 1970-79. from the data collected, tinea corporis emerged as the most frequently observed dermatophytosis, followed by tinea pedis and unguium. as far as dermatophytes are concerned, the dermatological pattern is dominated by microsporum canis and trichophyton rubrum. other species, such as epidermop ... | 1993 | 8015563 |
| influence of different oils on penetration of human hair by fungi. | synopsis the hair perforating ability of microsporum gypseum and trichophyton vanbreuseghemii was tested in presence of seventeen oils. clove, olive and turpentine oils were found to be fully inhibitory for hair penetration by both fungi. hair segments smeared with cantheridine oil and keocarpin hair vitalizer failed to reveal any perforation by t. vanbreuseghemii whereas arnica and shikakai oils showed little perforation by this fungus. résumé la capacité de pénétration du microsporum gypseum e ... | 1993 | 19272114 |
| effect of reducing agents on proteolytic and keratinolytic activity of enzymes of microsporum gypseum. | the effect of sodium sulphite, cysteine, glutathione, mercaptoethanol and dithioerythritol (0.1-10 mmol l-1) on the activity of proteases of microsporum gypseum was studied using azocasein, cross-linked bovine serum albumin and keratin as substrates. with the substrate without disulphide bonds (casein) no stimulation was found, and reducing agents inhibited proteolysis in most cases. with the remaining two substrates, all substances enhanced the activity of proteases probably through the cleavag ... | 1992 | 1284610 |
| [epidemiology of tinea capitis in bangui (central african republic)]. | in bangui (central african republic) an epidemiological survey making use of cluster sampling has been performed. prevalence rate is not very high in bangui (3.4%). boys are more infected than girls. both in rural and urban area prevalence rates are decreasing with age. microsporum langeronii has been identified in 98% of case. | 1992 | 1292802 |
| pattern of dermatophyte infection in singapore. | dermatophyte infection is the fourth commonest skin disorder seen in the national skin centre in singapore. a prospective study was carried out from june 1990 to march 1991 to determine the epidemiology and pattern of dermatophyte infections seen in this centre. two hundred patients who had a clinical diagnosis of dermatophyte infection and confirmed by direct microscopy were included into the study. cultures for dermatophyte were done on sabouraud's dextrose agar with chloramphenicol and cycloh ... | 1992 | 1295417 |
| structure modification and biological activity of some griseofulvin derivatives. | griseofulvin is an orally acting anti-fungal antibiotic with very limited water solubility. five chemical modifications were made on the griseofulvin structure in order to evaluate these changes on the antifungal and water solubility properties. antifungal activity was measured against tricophyton mentagrophytes, t. rubrum, t. terrestre, and microsporum canis. the oxime of griseofulvin was the most potent of the five compounds tested, but it was only of equal or less potency than griseofulvin. t ... | 1992 | 1296044 |
| low voltage scanning electron microscopy study of naftifine activity on microsporum canis. | scanning electron microscopy (sem) is at present considered a good way to observe the morphological alterations induced by an antifungal on pathogenic fungi. owing to its high precision, low voltage scanning electron microscopy (lvsem) improves the quality of observations. the microsporum canis morphology alterations induced by naftifine at a concentration of 0.9 microgram ml-1 (10 times the minimum inhibitory concentration (mic) for 7 days were studied in lvsem. the young lateral ramifications ... | 1992 | 1302809 |
| inhibition of growth of dermatophytes by indian hair oils. | a survey on the use of hair oils for hair dressings by the indian population revealed that mustard oil is preferred by males and coconut oil by females. amla oil is used equally by both. these oils contain different percentages of various saturated and unsaturated fatty acids which largely determine their toxicity against dermatophytes. for microsporum canis, m. gypseum and trichophyton rubrum, amla oil was most toxic, followed by cantharidine and coconut oil, while trichophyton mentagrophytes w ... | 1992 | 1302812 |
| in vitro and in vivo antidermatophytic activity of saperconazole, a new fluorinated triazole. | the in vitro activity of saperconazole against selected isolates of dermatophytes and its in vivo efficacy in a guinea pig dermatophytic infection model using trichophyton mentagrophytes were evaluated. susceptibility testing was determined with an agar dilution method in three media: yeast nitrogen base agar (ynba), brain heart infusion agar (bhia) and sabouraud dextrose agar (sda). an inoculum of 1 x 10(5) cfu of t. mentagrophytes spores was placed onto the surface of these agars. incubation w ... | 1992 | 1308468 |
| correlation between intracellular camp levels and phospholipids of microsporum gypseum. | atropine, a modulator of camp has been used to examine the relationship between phospholipids and intracellular levels of camp in microsporum gypseum. a decreased phospholipid content was observed in atropine grown cells as a result of reduced levels of intracellular camp. this decline was caused by the inhibitory effect of atropine on adenylate cyclase. lowered phospholipid content was supported by decreased [14c]acetate incorporation as well as reduced activities of key enzymes of phospholipid ... | 1992 | 1311953 |
| mycological findings in feline immunodeficiency virus-infected cats. | thirty-five fiv-seropositive cats and 55 fiv-seronegative matched cats were examined for yeasts (oropharyngeal swabs) and dermatophytes (hair brushings). the frequency of isolation of candida albicans and cryptococcus neoformans was significantly higher in the former group. the only dermatophyte isolated was microsporum canis. its prevalence was three times higher among fiv-infected cats than among control animals. | 1992 | 1325555 |
| outbreak of tinea capitis by trichophyton tonsurans and microsporum canis in niterói, rj, brazil. | 18 girls from an orphanage (orfanato santo antônio) in niterói presented tinea capitis due to trichophyton tonsurans (15 cases-83.3%) and microsporum canis (3 cases-26.7%). comments are made about clinical, mycological and therapeutic aspects of this microepidemic. | 1992 | 1342076 |
| [microsporum nanum. a fourth report of human infection in brazil]. | the authors present the fourth brazilian case of human microsporum nanum (m. nanum) infection. a child of nine months old presents cutaneous dorsal lesions compatible with tinea corporis, which appeared one month before. the culture revealed m. nanum. the lesions resolved spontaneously after a month. epidemiologic investigation in the patient's place of origin identified swine infected by m. nanum, indicating the probable source of the infection. | 1992 | 1342128 |
| phylogenetic relationships of the genera arthroderma and nannizzia inferred from mitochondrial dna analysis. | the phylogenetic relationship of the genera arthroderma and nannizzia, was investigated by mitochondrial dna analysis based on the restriction-fragment-length polymorphisms. phylogenetic trees made on ten species. a. benhamiae, a. insingulare, a. quadrifidum, a. simii, a. vanbreuseghemii, n. fulva, n. grubyia, n. gypsea, n. incurvata and n. otae showed no definite distinctions between the genera arthroderma and nannizzia. these results support the conclusion of weitzman et al. that the genera ar ... | 1992 | 1359414 |
| occurrence of keratinolytic fungi and related dermatophytes in soils in cairo, egypt. | 120 soil samples collected from various sites of cairo were processed for the isolation of keratinophilic fungi by "tokava" hair baiting technique. 22 species belonging to 6 genera were isolated viz.: chrysosporium tropicum, c. indicum, c. keratinophilum, c. queenslandicum, c. merdarium, c. anamorph of arthroderma curreyi, c. pannicola, c. lobatum, c. anamorph of renispora flavissima, c. pseudomerdarium, microascus mangini, malbranchea gypsea, ml. state of uncicarpus reesii, ml. state of coccidi ... | 1992 | 1380752 |
| evaluation of keratinolytic potential of some fungal isolates from gelatin factory campus. | during hair degradation, majority of organic sulphur was oxidized to inorganic sulphate and thiosulphate by four fungal isolates (cylindrocarpon lichenicola, graphium cuneiferum, microsporum gypseum, and m. fulvum) from gelatin factory soil. inorganic thiosulphate, an unusual metabolite, was regularly detected in the culture filtrates of all fungi, although in less amounts. maximum quantity (44 micrograms/ml) was released by g. cuneiferum on 50th day of incubation. all four fungi showed signific ... | 1992 | 1381699 |
| keratinophilic fungi isolated from soil of italian parks in the province of pavia. | soil samples collected from 9 parks in the italian province of pavia were baited with hair and feathers for the isolation of keratinophilic fungi. the dominant species were the teleomorphs arthroderma gypsea, a. uncinatum, ctenomyces serratus and aphanoascus fulvescens with their anamorphs. among the other species isolated, amauroascus mutatus, gymnascella dankaliensis, gymnoascus intermedius and gymnoascus reessii were recorded. the distribution of these fungi is discussed and related to previo ... | 1992 | 1383024 |
| [antimicrobial activity of selected aqua-carboxyl-cupric complexes]. | the activity of compounds of different structural types of aqua-complexes of the composition cu(r-coo)2.nh2o-methoxybenzoatocupric complexes, r = 2-, 3- and 4-methoxyphenyl (n = 1, 1 and 3); aryloxyacetatocupric complexes, r = phenoxymethyl (n = 3), 2-, 3- and 4-chlorophenoxymethyl (n = 4, 2 and 2) and 1-naphthoxymethyl (n = 4), and furthermore isomeric furanecarboxylato-(r = 2- or 3-furyl, n = 3, or 1) and thiophencarboxylatocupric complexes (r = 2- or 3-thienyl, n = 1 and 1), was examined by t ... | 1992 | 1394479 |
| incidence of dermatophytoses in rabbit farms in catalonia, spain, and its repercussion on human health. | over the past decades there has been an important increase in the incidence of dermatophytoses in humans as a result of contact with animals, although etiological agents can vary as can the animals transmitting the disease. a large-scale study was carried out in 220 farms raising rabbits for consumption. most of the farms (85%) were located in the autonomous community of catalonia (spain). mycological studies showed that 79.5% of the rabbits were infected with trichophyton mentagrophytes var. gr ... | 1992 | 1397196 |
| morphological and biochemical variability of microsporum canis strains. | seventy-two strains of microsporum canis, of different origins, were examined from a morphological point of view and tested in relation to their hydrolytic activity on tyrosine, xanthine, casein, gelatin, their ureasic activity and their capacity to assimilate different nitrogenous substances. the morphological aspects, that vary within the m. canis isolates, were constant in the strains isolated from rabbits. a strain with particular features was isolated many times from the dogs and cats comin ... | 1992 | 1397197 |
| forty four years of dermatophytes in a chicago clinic (1944-1988). | data are presented on 39,270 cultures taken over a 44 year span (1944-1988) at the university of chicago's dermatology clinic. in the mid 1940's microsporum audouinii accounted for 60-80% of isolates. it gradually decreased over the next two decades and disappeared altogether in the 1970's. trichophyton rubrum, rare in the 1940's accounted for over 60% of isolates in the mid-1960's only to be overtaken by t. tonsurans. this species, not isolated till the mid 1950's, became and remains the domina ... | 1992 | 1406904 |
| in vitro susceptibility to antimycotics of microsporum canis isolates from cats. | one hundred thirty-four isolates of microsporum canis, obtained from cats, were tested for in vitro susceptibility to various antifungal agents. the fungi were classified as susceptible, resistant, and intermediate by measuring the size of the zone of inhibited growth on yeast nitrogen base agar medium. clotrimazole had the highest activity (99.2%), followed by tioconazole (89.6%), griseofulvin (88.8%), econazole (73.1%), ketoconazole (50.7%), miconazole (15.7%), and isoconazole (12.7%). we foun ... | 1992 | 1429182 |
| microsporum gypseum complex in man and animals. | twenty-eight strains of the microsporum gypseum complex isolated from humans and animals were studied. the perfect form was found for 25 of the isolates. nannizzia incurvata was the species most frequently involved in human pathology, while nannizzia gypsea was most frequently found on animal lesions. nannizzia fulva was rarely involved pathologically and nannizzia corniculata was not isolated during this study. it is surprising to note that this species was not found even though most of our str ... | 1992 | 1432489 |