Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| an extracellular serine protease produced by vibrio vulnificus ncimb 2137, a metalloprotease-gene negative strain isolated from a diseased eel. | vibrio vulnificus is a ubiquitous estuarine microorganism but causes fatal systemic infections in immunocompromised humans, cultured eels or shrimps. an extracellular metalloprotease vvp/vvpe has been reported to be a potential virulence factor of the bacterium; however, a few strains isolated from a diseased eel or shrimp were recently found to produce a serine protease termed vvsa, but not vvp/vvpe. in the present study, we found that these strains had lost the 80 kb genomic region including t ... | 2011 | 22805945 |
| antimicrobial activity of rice bran extracts for diarrheal disease. | rice bran showed antioxidative, antimutagenic, carcinogenic and antibacterial activities in previous reports. the rice bran has been recently used as a natural source of health food for several diseases such as diabetes, atherosclerosis and cancer. severe diarrheal disease due to food-borne contamination of bacteria resulted from the bacteria have become resistant to many antibiotics. hence, early treatment of diarrhea using natural food containing antibacterial activity to prevent progression o ... | 2011 | 22619917 |
| temporal and spatial variability in the distribution of vibrio vulnificus in the chesapeake bay: a hindcast study. | vibrio vulnificus, an estuarine bacterium, is the causative agent of seafood-related gastroenteritis, primary septicemia, and wound infections worldwide. it occurs as part of the normal microflora of coastal marine environments and can be isolated from water, sediment, and oysters. hindcast prediction was undertaken to determine spatial and temporal variability in the likelihood of occurrence of v. vulnificus in surface waters of the chesapeake bay. hindcast predictions were achieved by forcing ... | 2011 | 22302219 |
| genetic diversity of the human pathogen vibrio vulnificus: a new phylogroup. | the biotype 3 group of the human pathogen vibrio vulnificus emerged in israel probably as a result of genome hybridization of two bacterial populations. we performed a genomic and phylogenetic study of v. vulnificus strains isolated from the environmental niche from which this group emerged - fish aquaculture in israel. the genetic relationships and evolutionary aspects of 188 environmental and clinical isolates of the bacterium were studied by genomic typing. genetic relations were determined b ... | 2011 | 22227412 |
| genetic and quantitative assessment of vibrio vulnificus populations in oyster (crassostrea virginica) tissues. | vibrio vulnificus is a leading cause of shellfish-associated food-borne illness. us regulations stipulate shellfish processing procedures to limit v. vulnificus densities; however, the effect of these procedures on v. vulnificus strain distribution and/or genetic diversity is unknown. vibrio vulnificus concentrations and strain diversity were analysed in various oyster tissues stored overnight at 26°c that were subsequently divided into two treatment groups: one received post-harvest processing ... | 2011 | 23761333 |
| serum antibodies to vibrio vulnificus biotype 3 lipopolysaccharide and susceptibility to disease caused by the homologous v. vulnificus biotype. | in 1996 an outbreak of severe soft tissue infections caused by vibrio vulnificus unexpectedly erupted in fish consumers in israel with relatively little morbidity in fish farmers. to test the hypothesis that recurrent exposure of fishermen to the virulent strain may have provided protection against severe or symptomatic disease, we investigated the association between the immune response to v. vulnificus biotype 3 lipopolysaccharide (bt3 lps) and disease susceptibility in fish farmers and fish c ... | 2011 | 20492749 |
| vibrio illness in florida, 1998-2007. | this study characterized the current epidemiology of vibrio infections in florida and examined cases reported from 1998 to 2007. logistic regression was used to determine risk of death. there were 834 vibrio infections in 825 individuals (average annual incidence rate 4·8/1,000,000). common vibrio species reported were vibrio vulnificus (33%), v. parahaemolyticus (29%), and v. alginolyticus (16%). most exposures were attributed to wounds (42%), and the most common clinical syndromes were wound i ... | 2011 | 20546636 |
| a novel and simple pcr walking method for rapid acquisition of long dna sequence flanking a known site in microbial genome. | acquisition of flanking sequence adjacent to a known dna site is an important task in microbial genome-related research. in this study, we developed a new method containing two rounds of pcr followed by cloning and sequencing. firstly, specific primer (sp) is added into the reaction system for primary locus-specific linear amplification, and then a complex long primer (clp) is added into the cooled reaction system for only one cycle. amplification products from the first round of pcr are directl ... | 2011 | 20878504 |
| rtx toxin enhances the survival of vibrio vulnificus during infection by protecting the organism from phagocytosis. | vibrio vulnificus is a marine bacterium causing serious septicemia and wound infection in humans. it produces an rtx toxin that can lyse a variety of cells and is important for virulence in mice. in this study, we explored the role of rtx in pathogenesis by characterizing an rtx-deficient mutant. this mutant showed an ~2-log reduction in virulence for mice infected by various routes. survival of the mutant at the infection site and subsequent spread into the bloodstream were impaired. in mice pr ... | 2011 | 21422475 |
| inactivation of vibrio vulnificus hemolysin through mutation of the n- or c-terminus of the lectin-like domain. | vibrio vulnificus is an etiological agent causing serious systemic infections in the immunocompromised humans or cultured eels. this species commonly produces a hemolytic toxin consisting of the cytolysin domain and the lectin-like domain. for hemolysis, the lectin-like domain specifically binds to cholesterol in the erythrocyte membrane, and to form a hollow oligomer, the toxin is subsequently assembled on the membrane. the cytolysin domain is essential for the process to form the oligomer. thr ... | 2011 | 21426913 |
| in-vitro antagonistic characteristics of crude aqueous and methanolic extracts of garcinia kola (heckel) seeds against some vibrio bacteria. | the methanolic and aqueous extracts of garcinia kola seeds were screened for their anti-vibrio activities against 50 vibrio isolates obtained from wastewater final effluents in the eastern cape province, south africa. the crude extracts at 10 mg/ml exhibited appreciable inhibitory activities against most of the test vibrio isolates, with zones of inhibition ranging from 10-19 mm for methanol extract and 8-15 mm for the aqueous extracts. the minimum inhibitory concentrations (mic) of the methanol ... | 2011 | 21441874 |
| dynamic analysis of pathogen-infected host cells using quantitative phase microscopy. | we present the real-time quantitative analysis of vibrio vulnificus-infected host cells using quantitative phase microscopy (qpm) based on interferometric techniques. this provides the ability to retrieve the phase or optical path-length distribution over the cell with nanometer path-length sensitivity from a single interferogram image. we have used qpm to study dynamic cell morphologic changes and to noninvasively quantify the cell volumes of rat basophilic leukemia rbl-2h3 cells infected with ... | 2011 | 21456868 |
| proteases produced by vibrios. | bacteria of the genus vibrio are normal habitants of the aquatic environment but the some species are believed to be human pathogens. pathogenic vibrios produce various pathogenic factors, and the proteases are also recognized to play pathogenic roles in the infection: the direct roles by digesting many kinds of host proteins or indirect roles by processing other pathogenic protein factors. especially vvp from vibrio vulnificus is thought to be a major pathogenic factor of the vibrio. although h ... | 2011 | 21467624 |
| factors affecting mortality in hong kong patients with upper limb necrotising fasciitis. | to identify predictive factors for mortality of patients with upper limb necrotising fasciitis. | 2011 | 21471588 |
| bacterial pathogens in hawaiian coastal streams-associations with fecal indicators, land cover, and water quality. | this work aimed to understand the distribution of five bacterial pathogens in o'ahu coastal streams and relate their presence to microbial indicator concentrations, land cover of the surrounding watersheds, and physical-chemical measures of stream water quality. twenty-two streams were sampled four times (in december and march, before sunrise and at high noon) to capture seasonal and time of day variation. salmonella, campylobacter, staphylococcus aureus, vibrio vulnificus, and v. parahaemolytic ... | 2011 | 21492899 |
| a survey of oysters (crassostrea gigas) in new zealand for vibrio parahaemolyticus and vibrio vulnificus. | a microbiological survey was conducted to determine the levels of total and pathogenic vibrio parahaemolyticus (vp) and vibrio vulnificus (vv) in pacific oysters (crassostrea gigas) collected from commercial growing areas in the north island, new zealand. the survey was intended to be geographically representative of commercial growing areas of pacific oysters in new zealand, while selecting the time frame most likely to coincide with the increased abundance of pathogenic vibrio species. vp was ... | 2011 | 21501884 |
| rapid and sensitive detection of vibrio vulnificus by loop-mediated isothermal amplification combined with lateral flow dipstick targeted to rpos gene. | a novel loop-mediated isothermal amplification (lamp) combined with amplicon detection by chromatographic lateral flow dipstick (lfd) assay was developed and evaluated for the detection of vibrio vulnificus. biotinylated lamp amplicons were produced by a set of six designed primers that recognized the v. vulnificus rna polymerase subunit sigma factor s (rpos) gene followed by hybridization with an fitc-labeled probe and lfd detection. the optimized time and temperature conditions for the lamp as ... | 2011 | 21513793 |
| comparison of the effects of environmental parameters on growth rates of vibrio vulnificus biotypes i, ii and iii by culture and quantitative pcr. | vibrio vulnificus is a natural inhabitant of estuarine waters. the three known biotypes include 1 (most human pathogens), 2 (primarily eel pathogens), and 3 (associated with fish and with human wound infections in israel). despite the frequently lethal consequences of v. vulnificus infections, the growth rates of the various biotypes and their response to environmental changes are not well characterized. we compared the specific growth rates (μ) of a representative of each biotype by culture and ... | 2011 | 21515718 |
| multiplex pcr assay for identification of three major pathogenic vibrio spp., vibrio cholerae, vibrio parahaemolyticus, and vibrio vulnificus. | a multiplex pcr assay was developed based on atpa-sequence diversification for molecular identification of 3 major pathogenic vibrio species: vibrio cholerae, vibrio parahaemolyticus, and vibrio vulnificus. it specifically identified them from among 133 strains of various vibrio species and other genera, and was applicable for testing seawater, suggesting its usefulness. | 2011 | 21530641 |
| modulation of iron-uptake systems by a mutation of luxs encoding an autoinducer-2 synthase in vibrio vulnificus. | vibrio vulnificus possesses multiple iron-uptake systems which are mediated by vuua (vulnibactin receptor), iuta (aerobactin receptor) and hupa (heme receptor). in this study, we determined the effect of a mutation of luxs encoding autoinducer-2 (ai-2) synthase on the expressions of the three receptors. a mutation and an in trans complementation of luxs did not affect the growing ability of v. vulnificus in iron-deficient conditions. nevertheless, the luxs mutation slightly decreased vuua expres ... | 2011 | 21532149 |
| inactivation kinetics of vibrio vulnificus in phosphate-buffered saline at different freezing and storage temperatures and times. | vibrio vulnificus (vv) is a pathogen that can be found in raw oysters. freezing can reduce vv and increase the shelf life of oysters. the objective of this study was to develop predictive inactivation kinetic models for pure cultures of vv at different frozen storage temperatures and times. vv was diluted in phosphate-buffered saline (pbs) to obtain about 10(7) cfu/ml. samples were frozen at -10, -35, and -80 °c (different freezing rates), and stored at different temperatures. survival of vv was ... | 2011 | 21535763 |
| the pseudomonas quinolone signal (pqs), and its precursor hhq, modulate interspecies and interkingdom behaviour. | the pseudomonas quinolone signal (pqs), and its precursor 2-heptyl-4-quinolone (hhq), play a key role in coordinating virulence in the important cystic fibrosis pathogen pseudomonas aeruginosa. the discovery of hhq analogues in burkholderia and other microorganisms led us to investigate the possiblity that these compounds can influence interspecies behaviour. we found that surface-associated phenotypes were repressed in gram-positive and gram-negative bacteria as well as in pathogenic yeast in r ... | 2011 | 21539583 |
| vibrio parahemolyticus septicaemia in a liver transplant patient: a case report. | abstract: introduction: vibrio parahemolyticus is the leading cause of vibrio-associated gastroenteritis in the united states of america, usually related to poor food handling; only rarely has it been reported to cause serious infections including sepsis and soft tissue infections. in contrast, vibrio vulnificus is a well-known cause of septicaemia, especially in patients with cirrhosis. we present a patient with v. parahemolyticus sepsis who had an orthotic liver transplant in 2007 and was on i ... | 2011 | 21548914 |
| a conserved gtpase ychf of vibrio vulnificus is involved in macrophage cytotoxicity, iron acquisition, and mouse virulence. | vibrio vulnificus, a highly virulent marine bacterium, causes serious wound infections and fatal septicemia in many areas of the world. to identify v. vulnificus genes required for killing macrophages, we made an insertional mutant library of v. vulnificus and screened it for reduced macrophage cytotoxicity. one mutant defective in macrophage cytotoxicity had an insertion in ychf, a gene encoding a putative gtpase. in addition to reduced cytotoxicity, this mutant had attenuated growth in iron-li ... | 2011 | 21570909 |
| [development of an immunochromatographic strip test for rapid detection of vibrio vulnificus.] | objective: to establish a rapid strip test for detection of vibrio vulnificus. method: anti-vibrio vulnificus polyclonal antibodies were obtained from the rabbits immunized with vibrio vulnificus (atcc27562). colloidal gold was prepared through reducing haucl(4)·4h(2)o by sodium citrate and conjugated with the polyclonal antibodies as the detecting reagent. the polyclonal antibodies and sheep anti-rabbit immunoglobulins were separately coated onto the same nitrocellulose membrane for sample dete ... | 2011 | 21602152 |
| frsa functions as a cofactor-independent decarboxylase to control metabolic flux. | the interaction between fermentation-respiration switch (frsa) protein and glucose-specific enzyme iia(glc) increases glucose fermentation under oxygen-limited conditions. we show that frsa converts pyruvate to acetaldehyde and carbon dioxide in a cofactor-independent manner and that its pyruvate decarboxylation activity is enhanced by the dephosphorylated form of iia(glc) (d-iia(glc)). crystal structures of frsa and its complex with d-iia(glc) revealed residues required for catalysis as well as ... | 2011 | 21623357 |
| transgenic expression of tilapia hepcidin 1-5 and shrimp chelonianin in zebrafish and their resistance to bacterial pathogens. | recently, tilapia hepcidin (th)1-5 was characterized, and its antimicrobial functions against several pathogens were reported. the antimicrobial functions of another shrimp antimicrobial peptide (amp), chelonianin, were also characterized using a recombinant chelonianin protein (rcf) that was expressed by a stably transfected chinese hamster ovary (cho) cell line against pathogen infections in fish. the function of the overexpression of both amps in zebrafish muscles was not examined in previous ... | 2011 | 21642002 |
| temporal and spatial variability in culturable pathogenic vibrio spp. in lake pontchartrain, louisiana, usa, following hurricanes katrina and rita. | we investigated the abundance, distribution, and virulence gene content of v. cholerae, v. parahaemolyticus, v. vulnificus in the waters of southern lake pontchartrain in louisiana, usa, on four occasions from october 2005 to september 2006, using selective cultivation and molecular assays. the three, targeted pathogenic vibrios were generally below detection in january 2006 when the water was cold (13° c), and highest in september 2006 when lake water was warmest (30° c). the maximum values for ... | 2011 | 21642406 |
| identification and characterization of a novel serine protease vvps containing two functional domains and essential for autolysis of vibrio vulnificus. | little is known about the molecular mechanism for autolysis of gram (-) bacteria. in the present study, we identified the vvps gene encoding a serine protease, vvps, from vibrio vulnificus, a gram (-) food-born pathogen. the amino acid sequence predicted that vvps consists of two functional domains, an n-terminal protease catalytic domain (pcd) and c-terminal carbohydrate binding domain (cbd). a null mutation of vvps significantly enhanced viability during stationary phase, as measured by enumer ... | 2011 | 21642466 |
| design and validation of a novel multiplex real-time pcr assay for vibrio pathogen detection. | three species--vibrio cholerae, vibrio parahaemolyticus, and vibrio vulnificus--account for the majority of vibrio infections in humans. rapid and accurate identification of vibrio species has been problematic because phenotypic characteristics are variable within species. additionally, biochemical identification and confirmation require 2 or more days to complete. rapid and sensitive molecular techniques for the detection of vibrio pathogens would be useful for the surveillance and management o ... | 2011 | 21669071 |
| chitin-induced carbotype conversion in vibrio vulnificus. | as an etiological agent of bacterial sepsis and wound infections, vibrio vulnificus is unique among the vibrionaceae. the most intensely studied of its virulence factors is the capsular polysaccharide (cps). over 100 cps types have been identified, yet little is known about the genetic mechanisms that drive such diversity. chitin, the second-most-abundant polysaccharide in nature, is known to induce competence in vibrio species. here, we show that the frequency of chitin-induced transformation i ... | 2011 | 21670169 |
| necrotising fasciitis caused by vibrio vulnificus in the lower limb following exposure to seafood on the hand. | vibrio vulnificus infection mainly manifests as primary bacteraemia or gastroenteritis following injection of the microorganism, and wound infection through direct inoculation. injury from exposure to the microorganism and development of necrotising fasciitis at a remote site and sepsis are rare. this report is of a high-risk patient with haemoglobin h disease who developed necrotising fasciitis in the lower limb after exposure to seafood on the hand. | 2011 | 21813906 |
| functional characterization of epsc, a component of the type ii secretion system, in the pathogenicity of vibrio vulnificus. | epsc, one of the components comprising the type ii secretion system (t2ss), was isolated from a human pathogenic bacterium, vibrio vulnificus, to evaluate its role in eliciting virulence. an espc-deleted mutant v. vulnificus displayed a reduced cytotoxicity to the human cell line hep-2 and an attenuated virulence in a mouse model. this mutant exhibited dramatic defects in secretion of diverse extracellular proteins, such as outermembrane proteins, transporters, and the known secreted factors, no ... | 2011 | 21788383 |
| a new leukocyte cell-derived chemotaxin-2 from marine fish grouper, epinephelus coioides: molecular cloning and expression analysis. | leukocyte cell-derived chemotaxin-2 (lect2) is a multifunctional protein involved in cell growth, differentiation and autoimmunity. in this study, a new leukocyte cell-derived chemotaxin-2 (eclect2) gene was cloned from grouper, epinephelus coioides, by rapid amplification of cdna ends (race) pcr. the full-length cdna sequence of eclect2 was 595 bp in size, containing a 5'-untranslated region (utr) of 44 bp and a 3'-utr of 83 bp. the deduced protein sequence of the open reading frame (465 bp) sh ... | 2011 | 21763428 |
| insights into the antibacterial and immunomodulatory functions of tilapia hepcidin (th)2-3 against vibrio vulnificus infection in mice. | the antimicrobial and immunomodulatory functions of the antimicrobial peptide, tilapia hepcidin (th)2-3, against a bacterial endotoxin under in vitro conditions was previously reported. in this study, we investigated the antibacterial and immunomodulatory functions of th2-3 in mice infected with the pathogen, vibrio vulnificus. a th2-3 injection in v. vulnificus-infected mice produced an increased survival rate compared to mice injected with v. vulnificus only. in addition, a th2-3 injection inc ... | 2011 | 21756935 |
| the antifouling potentiality of galactosamine characterized from vibrio vulnificus exopolysaccharide. | to gain a better insight into biofilm composition, the exopolysaccharide (eps) of the gram-negative bacterium vibrio vulnificus was studied. monosaccharide composition analysis of the wild-type and mutant v. vulnificus eps carried out with bio-liquid chromatography revealed the presence of d-glucosamine, d-galactose, d-glucose and d-xylose in both strains. d-galactosamine was found only in the mutant that formed less biofilm compared to its wild-type. the influence of galactosamine on biofilm fo ... | 2011 | 21827336 |
| comparative analysis of proteins in the culture supernatants of human intestinal epithelial cells infected with the wild-type and rtxe mutant of vibrio vulnificus. | bacterial virulence factors and secreted extracellular proteins from damaged host cells following infection have been recognized as key mediators in the pathophysiological alterations observed in septic shock, and have also been shown to have a synergistic influence on bacterial pathogenicity. we hypothesized that during infections, virulence factors as well as host-shed proteins may synergistically influence aspects of the pathogenicity of v.-ávulnificus, such as primary septic shock and overpr ... | 2011 | 21725587 |
| influence of iron-chelated growth conditions on outer membrane protein production and virulence of vibrio tubiashii. | growth of two vibrio tubiashii strains under iron-chelated conditions resulted in the production of a hydroxymate-like siderophore, and expression of outer membrane proteins with homologies to proteins in vibrio cholerae and vibrio vulnificus which were not seen in cells grown under non-chelated growth conditions. pcr analysis using primers based on listonella anguillarum's ferric uptake repressor protein (fur) gene detected a 316-ábp fur gene homolog which also had sequence homology to the fur ... | 2011 | 21839393 |
| genomic and metabolic profiling of nonulosonic acids in vibrionaceae reveal biochemical phenotypes of allelic divergence in vibrio vulnificus. | nonulosonic acids (nulos) encompass a large group of structurally diverse nine-carbon backbone +¦-keto sugars widely distributed among the three domains of life. mammals express a specialized version of nulos called sialic acids, which are displayed in prominent terminal positions of cell surface and secreted glycoconjugates. within bacteria, the ability to synthesize nulos has been demonstrated in a number of human pathogens and is phylogenetically widespread. here we examine the distribution, ... | 2011 | 21724895 |
| intranasal immunization with recombinant pspa fused with a flagellin enhances cross-protective immunity against streptococcus pneumoniae infection in mice. | streptococcus pneumoniae is a major respiratory pathogen that causes high levels of mortality and morbidity in infants and the elderly. despite the use of antibiotics and vaccines, fatal pneumococcal disease remains prevalent. pneumococcal surface protein a (pspa), a highly immunogenic surface protein produced by all strains of s. pneumoniae, can elicit protective immunity against fatal pneumococcal infection. we have previously demonstrated that the vibrio vulnificus flab, a bacterial flagellin ... | 2011 | 21696869 |
| occurrence and potential pathogenesis of vibrio cholerae, vibrio parahaemolyticus and vibrio vulnificus on the south coast of sweden. | during the summer of 2006, several wound infections - of which three were fatal - caused by vibrio cholerae were reported from patients who had been exposed to water from the baltic sea. before these reports, we initiated a sampling project investigating the occurrence of potential human pathogenic v. cholerae, vibrio vulnificus and vibrio parahaemolyticus in the sound between sweden and denmark. the blue mussel (mytilus edulis) was used as an indicator to follow the occurrence of vibrios over t ... | 2011 | 21692819 |
| Vibrio virulence genes in fishes collected from estuarine waters in Italy. | Aims:ÔÇé The aim of this study was to investigate the presence of Vibrio vulnificus and potentially pathogenic strains of Vibrio parahaemolyticus in mullets collected from estuarine environment in Italy. Methods and Results:ÔÇé Two hundred and ninety-five mullets were analysed by culture using the selective medium thiosulfate citrate bile salt sucrose agar, during a monitoring period of 2ÔÇâyears (2008-2009). Presumptive Vibrio colonies were initially identified by using biochemical tests, and s ... | 2011 | 21740448 |
| Detection and characterization of pathogenic vibrios in shellfish by a Ligation Detection Reaction-Universal Array approach. | Vibrios are a group of major foodborne pathogens widely distributed in marine environment. Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio vulnificus are the pathogenic species of Vibrio that pose the greatest threat to human health. However, other vibrios, e.g. Vibrio alginolyticus, Vibrio mimicus and Grimontia hollisae, apparently less relevant in the group of foodborne pathogens, have been sporadically found in outbreaks. For seafood safety and economic purposes, a rapid and powerful met ... | 2011 | 22177227 |
| morbidity and mortality of carotid endarterectomy under local anesthesia: a retrospective study. | it has been shown that carotid endarterectomy reduces the incidence of stroke in patients with symptomatic extracranial occlusive vascular disease in the absence of major perioperative complications such as stroke or death. we present a retrospective study of 106 carotid endarterectomies performed under local anesthesia in 100 patients in whom transient ischemic attack (tia) or minor stroke had occurred. nonfatal stroke occurred in 2%, and tia occurred in 1%. there was no perioperative mortality ... | 2011 | 3059211 |
| the management of dyspepsia. | 2011 | 3245006 | |
| the management of dyspepsia. | 2011 | 3245006 | |
| [the anti-insulin receptor antibody syndrome]. | 2011 | 3785115 | |
| total occlusion of the left main coronary artery in chronic stable angina pectoris. | 2011 | 3209223 | |
| [esophagectomy via a right-sided thoracic approach. role of the circulating nurse]. | 2011 | 3206015 | |
| [microcomputers used in administration in the private dental practice]. | 2011 | 3270215 | |
| [microcomputers used in administration in the private dental practice]. | 2011 | 3270215 | |
| [a giant lipoma of the spermatic cord]. | 2011 | 3210616 | |
| [a combination of an accessory large intestine and teratoid cysts of the intrapelvic tissue]. | 2011 | 3210612 | |
| karyological studies in coris julis (pisces, labridae). | in the present investigation the diploid number 2n = 48 (nf = 58) has been determined for females, primary males, and secondary males of coris julis from the gulf of palermo. differentiated sex chromosomes have not been observed in the population under study. | 2011 | 3234765 |
| [new aspects of vitamin k prophylaxis in newborn infants and infants]. | discussion about vitamin k prophylaxis has again become a matter of major concern since cases of life threatening bleeding due to late onset vitamin k deficiency have been observed in germany. this review tries to summarize present knowledge about the clinical presentation, pathogenesis and the potential prevention of vitamin k deficiency caused bleeding in the neonatal period and infancy. | 2011 | 3785234 |
| cleavage lines of the oral mucosa in japanese cadavers. | cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria. | 2011 | 3165386 |
| an investigation into the relative sealing ability of five commercially used temporary restorative materials. | 2011 | 3165335 | |
| clinical experience with a new formulation of midazolam--10mgs in 5ml solution. | 2011 | 3159107 | |
| [the origins of public health nursing]. | 2011 | 3147266 | |
| bioaffinity sensors. | 2011 | 3131631 | |
| progestins and oral contraceptive-induced lipoprotein changes: a prospective study. | in order to determine the effects on plasma lipoproteins of oral contraceptives containing progestins with varying androgenic potency, 136 healthy women were randomized into 3 groups and followed prospectively for one year while receiving either 50 mcg ethinyl estradiol and 1.0 mg ethynodiol diacetate (eed), 50 mcg ethinyl estradiol and 1.0 mg norethindrone acetate (ena), or 50 mcg ethinyl estradiol and 0.5 mg d-1 norgestrel (eng). comparison was made to a self-selected group of 50 women using a ... | 2011 | 3096633 |
| subcutaneous bronchogenic cysts. | recent experience with a bronchogenic cyst occurring in a subcutaneous suprasternal location presents an additional entity to be considered in the differential diagnosis of head and neck lesions, and correlates with the embryology of the developing tracheobronchial tree and sternum. a review of subcutaneous bronchogenic cysts shows 41 cases have been described in the english literature. most were noted in the suprasternal location; all but one were first noted in infancy or childhood. there is a ... | 2011 | 3072402 |
| [pharmacokinetic and toxicologic aspects of stress]. | 2011 | 3069119 | |
| [use of photosensitizing preparations in the treatment of cancer of the orl organs]. | 2011 | 3067440 | |
| membrane phospholipids alter nutrient transport and drug toxicity in tumorigenic fibroblasts. | the phospholipid polar head group composition of lm cell plasma membranes was nutritionally altered by choline analogue supplementation. phosphatidylcholine (pc), normally 60% of total phospholipid, was depleted by 60 to 90% in membranes from cells cultured with n, n'-dimethylethanolamine (dme), n-monomethylethanolamine (me), and ethanolamine (e). enrichment of lm cell membranes with choline analogues, such as dme-, me-, and e-containing phospholipids, decreased the transport of [3h]thymidine, [ ... | 2011 | 3032553 |
| a preliminary study of a combination chemotherapy with ifosfamide, adriamycin and cisplatin for endometrial carcinoma. | seven patients with uterine endometrial carcinoma received a postoperative combination chemotherapy with ifosfamide (1g/m2) daily for 5 days, and adriamycin (50mg/m2) and cisplatin (50mg/m2) on day 1 (iap). all except one patient with the disease without myometrial invasion received 5 courses or more of iap treatment. of four patients with measurable disease, three achieved complete response (cr) and the other patient obtained partial response (pr), indicating a 100% response rate. in the pr cas ... | 2011 | 3209914 |
| emphasis on preventive perinatology: a suitable alternative for developing countries. | the potential efficacy of preventive interventions in latin america to reduce perinatal morbidity and mortality is reviewed. the most important perinatal risk factors associated with pregnancy and delivery are young age of the mother, low socioeconomic status, low education, malnutrition, lack of prenatal care, pregnancy-induced-hypertension, perinatal infections, alcohol, smoking, and iatrogenic causes. adequate data are lacking to determine the magnitude of these factors in latin america. iatr ... | 2011 | 3065947 |
| [iron deficiency and food habits in the 1st year of life]. | 2011 | 3185434 | |
| changes in body proportions of japanese medical students between 1961 and 1986. | since 1945, the japanese physique has changed a great deal. physical examinations of medical students at kyushu university have been carried out on an annual basis since 1939. we investigated changes in body proportions using data on 813 medical students examined from 1961 to 1986. during these 26 years, standing height has increased by 4.69 cm, arm length by 2.58 cm, and sitting height by 0.79 cm. thus, the japanese have grown taller and their extremities are longer, yet the trunk has not chang ... | 2011 | 3189519 |
| racism, the national health service, and the health of black people. | racism has been and is central to an understanding of the health of black people in britain. black people have played and are playing a central role in the national health service (nhs). their role is, however, shaped by racism. their experiences as consumers of the nhs are also shaped by racism--in terms of their treatment for both physical and mental health problems. in addition, their specific health problems such as sickle cell anemia have not received the attention they deserve. the nhs has ... | 2011 | 3049409 |
| valproate-associated hepatotoxicity and its biochemical mechanisms. | intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ... | 2011 | 3131628 |
| intestinal obstruction during pregnancy and the puerperium at mpilo central hospital. | 2011 | 3225798 | |
| economic rights of the institutionalized mentally disabled. | 2011 | 3319919 | |
| [x-ray computed tomography in venous pathology]. | after presenting the tomodensitometric semiology of venous thromboses in various territories, the authors define its indications. it is essentially in deep territories, head, chest and abdomen that the ct-scan is used to study and diagnose unrecognized thromboses as well as determine the venous repercussion of various neighboring ailments. the respective place of the ct-scan, ultrasonography and various phlebographies is analyzed. | 2011 | 3043474 |
| muscle function in women with rheumatoid arthritis--the influence of glucocorticosteroids. a clinical and morphological investigation. | 2011 | 3187461 | |
| [academic dissertations of military pharmacists on the history of pharmacy]. | 2011 | 3067684 | |
| phlegmonous necrotising cellulitis after reduction mammoplasty. a report of 4 cases. | 2011 | 3187790 | |
| synthesis and antineoplastic effects of furo[3,4-d]pyrimidine derivatives. | furo[3,4-d]pyrimidine was obtained in the reaction of 2-phenyl-4-phenylamino-6-methyl-5-pyrimidinecarboxylic acid with socl2. this compound, heated with aliphatic amines, yielded mono- and diamino-derivatives. some of the obtained compounds exhibited a potent antineoplastic activity. | 2011 | 3237569 |
| oesophageal pain exacerbated by propranolol. | 2011 | 3113570 | |
| deficiency of eosinophil peroxidase detected by automated cytochemistry. | 2011 | 3122494 | |
| annual summary 1984. reported morbidity and mortality in the united states. | 2011 | 3092006 | |
| phenazopyridine-induced methemoglobinemia. | 2011 | 3234262 | |
| [aspergilloma of the lung in djibouti]. | 2011 | 3233037 | |
| evaluation of tenoxicam in rheumatology--clinical trial results in argentina and brazil. | the therapeutic activity of tenoxicam, a thienothiazine derivative with analgesic and anti-inflammatory properties, has been studied by 15 investigators in argentina and brazil. twenty-nine clinical trials were performed in a total of 747 patients suffering from rheumatoid arthritis (270), cox- and gonarthrosis (190), extra-articular inflammation (250) and acute gout (37). out of the patients studied, 507 received tenoxicam and 240 were given comparative preparations. in 76% of the patients 20 m ... | 2011 | 3329108 |
| evaluation of tenoxicam in rheumatology--clinical trial results in argentina and brazil. | the therapeutic activity of tenoxicam, a thienothiazine derivative with analgesic and anti-inflammatory properties, has been studied by 15 investigators in argentina and brazil. twenty-nine clinical trials were performed in a total of 747 patients suffering from rheumatoid arthritis (270), cox- and gonarthrosis (190), extra-articular inflammation (250) and acute gout (37). out of the patients studied, 507 received tenoxicam and 240 were given comparative preparations. in 76% of the patients 20 m ... | 2011 | 3329108 |
| ferriprotoporphyrin ix mediated oxygen activation/insertion reactions: the anerobic reduction of the aniline-fe3+-microperoxidase-8 complex by nadh. | a spectrophotometric study of the reduction of the fe3+ microperoxidase-8-aniline (fe3+-mp-8-an) complex has been carried out. addition of nadh to a solution of fe3+-mp-8-an under strictly anerobic conditions results in the formation of a species with lambda max = 414 nm (fe3+-mp-8-an lambda max 407 nm). the kinetics of formation of this species show an induction period (tau) which follows saturation kinetics with respect to [aniline] with km(app) = 2.2 x 10(-3) mol dm-3, i.e., close to that obt ... | 2011 | 3236002 |
| [twin pregnancies with intrauterine fetal death of one fetus]. | 2011 | 3234930 | |
| construction of hygromycin-resistant retroviral cloning vectors. | 2011 | 3205745 | |
| the use of methotrexate in steroid-resistant systemic lupus erythematosus. | although the use of methotrexate (mtx) is gaining acceptance in the treatment of several connective tissue diseases, there is little evidence of its therapeutic value in systemic lupus erythematosus (sle). we examined the response to mtx in patients with steroid-resistant sle in an open, unblinded study. of 10 sle patients treated with mtx (7.5 mg/weekly), 7 showed improvement. the other 3 stopped therapy because of lack of response or because of side effects. improvements were noted within 3 mo ... | 2011 | 3288223 |
| the use of methotrexate in steroid-resistant systemic lupus erythematosus. | although the use of methotrexate (mtx) is gaining acceptance in the treatment of several connective tissue diseases, there is little evidence of its therapeutic value in systemic lupus erythematosus (sle). we examined the response to mtx in patients with steroid-resistant sle in an open, unblinded study. of 10 sle patients treated with mtx (7.5 mg/weekly), 7 showed improvement. the other 3 stopped therapy because of lack of response or because of side effects. improvements were noted within 3 mo ... | 2011 | 3288223 |
| [accidental inversion of the gastroscope in the esophagus]. | 2011 | 3197612 | |
| fructosamine concentrations in the serum of diabetics and healthy individuals in singapore. | 2011 | 3252462 | |
| fructosamine concentrations in the serum of diabetics and healthy individuals in singapore. | 2011 | 3252462 | |
| [use of chickpea (cicer arietinum l.) in non-dairy formulas. ii. nitrogen balance in children with lactose intolerance, fed with a formula based on chickpea and a commercial soybean product]. | the nutritive value of chick-pea and soy infant formulas was evaluated. nitrogen balance was performed in 17 malnourished babies, seven of which were fed with the chick-pea formula, and 10 with the soy commercial formula (sobee). the percentage of absorption, retention and biological value of the chick-pea formula were 72.4, 26.4 and 35.1, respectively and 69.6, 24.3 and 34.0 in the same order, with the soy formula. since the nutritional quality of the chick-pea was not different to the commerci ... | 2011 | 3146951 |
| what can pediatricians do for the children in asia in the 21st century? (the philippine vision). | 2011 | 3149125 | |
| the clinical and pathophysiologic implications of pain, st abnormalities, and scintigraphic changes induced during dipyridamole infusion: their relationships to the peripheral hemodynamic response. | in order to determine their significance during dipyridamole perfusion scintigraphy, symptomatic, ecg, and scintigraphic findings were related to each other, to the hemodynamic response, and to angiographic findings in 73 consecutive patients having coronary angiography within 3 months of scintigraphy. the group having induced "cardiac" pain differed from the group without induced pain only in their higher incidence of induced ischemic st changes, the "marked" hemodynamic response, and their low ... | 2011 | 3177178 |
| interleukin-1 stimulation in the esrd patient: potential long-term consequences. | 2011 | 3118543 | |
| partial lipodystrophy: report of a case. | 2011 | 3114415 | |
| hypopigmented mycosis fungoides. speculations about the mechanism of hypopigmentation. | hypopigmented, nonatrophic macules are an unusual manifestation of lesions of early mycosis fungoides. presented herein is a patient with such lesions and an unusual mask-like hypopigmentation of the face. we review both the clinical and microscopic findings in this patient and in previously reported patients with hypopigmented lesions of mycosis fungoides. finally, speculation is made as to the mechanisms of the hypopigmentation. | 2011 | 3766921 |
| treatment of localized neuroblastoma. | the treatment of neuroblastoma must take into account the prognosis as determined at the time of diagnosis. the stage is an important prognostic factor. in evans's stage i neuroblastoma, surgery is curative in itself and adjuvant treatment is not needed. in evans' stage ii, it is our opinion that the presence of involved lymph nodes worsens the prognosis. therefore, we suggest that patients with stage ii should be divided into stage iia (without lymph node involvement) and stage iib (with lymph ... | 2011 | 3766913 |