Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [in vitro antibacterial activity of fleroxacin (flrx) against clinical isolates from bacterial enteritis]. | antibacterial activity of fleroxacin (flrx), a new quinolone antimicrobial, against 36 strains of shigella app., 14 strains of salmonella spp., 11 strains of escherichia coli, 9 strains of vibrio spp. (including 2 strains of v. cholerae o1), 14 strains of campylobacter jejuni/coli, 3 strains of aeromonas spp. and 1 strain of plesiomonas shigelloides isolated from infectious enteritis patients in this study was determined. its activity was compared with that of ciprofloxacin (cpfx), norfloxacin ( ... | 1994 | 7829909 |
| enteropathogens associated with acute diarrhoeal diseases. | five types of escherichia coli are responsible for as much as 25% of all diarrheal diseases in developing countries. they tend to be transmitted via contaminated foods, particularly weaning foods, and water. they include enterotoxigenic, enteropathogenic, enteroadherent, enteroinvasive, and enterohemorrhagic e. coli. shigella species are responsible for 10-15% of acute diarrheas in children less than 5 years old and the most common etiologic agents of childhood dysentery. shigellosis is common i ... | 1994 | 7835992 |
| agammaglobulinaemia. | agammaglobulinaemia is the most common of the primary immunodeficiencies. three major types can be distinguished: x-linked agammaglobulinaemia, early-onset agammaglobulinaemia and late-onset agammaglobulinaemia. in x-linked agammaglobulinaemia, the molecular defect has been elucidated, and genetic counseling, prenatal diagnosis and carrier detection have become important issues. the pathogenesis of early- and late-onset agammaglobulinaemia is heterogeneous and usually not within the b-cell linea ... | 1994 | 7838240 |
| antibodies against some bacterial antigens in children. | the prevalence of bacterial antibodies was determined in 173 children aged 0-15 years. the prevalence of igg borrelia burgdorferi antibodies in titres > 500 in children less than 8 years of age was 6% while none of the older children had these antibodies in titres > 400. igg helicobacter pylori antibodies were detected only in children older than 6 years of age, with a prevalence of 6.5%, as were iga h. pylori antibodies, with a prevalence of 3.7%. the prevalence of high-titre igg campylobacter ... | 1994 | 7841725 |
| the pathogenesis of campylobacter jejuni. | studies on the pathogenesis of campylobacter jejuni show that for this organism to cause disease the susceptibility of the host and the relative virulence of the infecting strain are both important. infection with c. jejuni results from the ingestion of contaminated food or water, and the infective dose can be as low as 800 organisms. to initiate infection the organism must penetrate the gastrointestinal mucus, which it does by using its high motility and spiral shape. the bacteria must then adh ... | 1994 | 7841837 |
| [an enzyme-linked immunosorbent assay for the detection of igg antibodies against urease of helicobacter pylori]. | we have developed an enzyme-linked immunosorbent assay (elisa) for the detection of igg antibodies against helicobacter pylori (hp) using purified hp urease as an antigen. the urease was purified from ultrasonicated extract of hp by nacl linear gradient system on deae-sepharose 4b chromatography. two molecular weight bands, 65kd and 27kd were observed on a sds-page gel in the purified urease sample. the urease antigen did not crossreact to rabbit antibodies prepared against campylobacter coli an ... | 1994 | 7844892 |
| impairment of na+,k(+)-atpase activity following enterotoxigenic campylobacter jejuni infection: changes in na+, cl- and 3-o-methyl-d-glucose transport in vitro, in rat ileum. | unidirectional fluxes of na+, cl- and 3-o-methyl-d-glucose (3-mg) were measured in vitro across campylobacter jejuni live culture-infected and control rat ileal short-circuited tissues by the ussing chamber technique. net secretion of na+ and enhanced secretion of cl- ions was observed in the infected animals (p < 0.001, n = 6) as compared to the net absorption of na+ and marginal secretion of cl- ions in the control animals. there was a significant decrease in the mucosal-to-serosal fluxes of 3 ... | 1994 | 7851745 |
| cryptolepis sanguinolenta activity against diarrhoeal bacteria. | cryptolepine is the main alkaloid of cryptolepis sanguinolenta (lindl.) schlechter, a plant used in traditional medicine in west africa. the minimal inhibitory concentrations (mics) of cryptolepine, ethanol and aqueous extracts of cryptolepis sanguinolenta root were determined for 65 strains of campylobacter jejuni, 41 strains of campylobacter coli isolated from sporadic cases of gastroenteritis in portugal and 86 strains of vibrio cholerae isolated from patients with enteric infections in angol ... | 1994 | 7853867 |
| oxygen tolerance estimates in campylobacter species depend on the testing medium. | oxygen tolerance of the microaerophile campylobacter jejuni subsp. jejuni varied with different brands of complex media which were used for plating the dilute cell suspensions. the tryptone component was one factor. with some tryptones growth occurred at 21% oxygen whereas with others there was no growth at oxygen levels of 15% or higher. a chemically-defined, agar-solidified plating medium was used to estimate the oxygen tolerance of camp. jejuni subsp. jejuni, camp. coli and camp. fetus subsp. ... | 1994 | 7822225 |
| identification of campylobacter jejuni, campylobacter coli and campylobacter lari by the nucleic acid amplification system nasbar. | nasbar, an isothermal amplification technique for nucleic acids, was evaluated for the specific identification of campylobacter jejuni, camp. coli and camp. lari. a set of primers and a probe were chosen from the 16s rrna sequence of campylobacter. the probe was hybridized in solution with the amplified nucleic acids of 12 campylobacter species and nine other gram-negative bacteria. the probe was shown to hybridize specifically to the amplified single-stranded rna of camp. jejuni, camp. coli and ... | 1994 | 7822229 |
| isolation of motile and non-motile insertional mutants of campylobacter jejuni: the role of motility in adherence and invasion of eukaryotic cells. | a method of insertional mutagenesis for naturally transformable organisms has been adapted from haemophilus influenzae and applied to the study of the pathogenesis of campylobacter jejuni. a series of kanamycin-resistant insertional mutants of c. jejuni 81-176 has been generated and screened for loss of ability to invade int407 cells. eight noninvasive mutants were identified which showed 18-200-fold reductions in the level of invasion compared with the parent. three of these eight show defects ... | 1994 | 7715450 |
| a pcr assay for the detection of campylobacter jejuni and campylobacter coli in water. | a pcr assay has been developed for the detection of campylobacter jejuni and camp. coli in water samples. the sample is filtered through a membrane which is subjected to sonication to release the impacted cells. after removal of the filter from the cell suspension and a freeze/thaw cell lysis step, a semi-nested pcr is carried out on the filtrate using the primers cf02, cf03 and cf04 (camp. jejuni flaa and flab gene sequences). incorporation of a sonication stage allows removal of the filter mem ... | 1994 | 7765441 |
| inhibition of dnase activity in pfge analysis of dna from campylobacter jejuni. | dnase-positive strains of campylobacter jejuni degrade their chromosomal dna during standard preparative procedures before pulsed-field gel electrophoresis (pfge). a simple method for inactivation of this dnase activity is described. formaldehyde fixation of the bacterial cells resulted in the preservation of the dna in a state suitable for restriction digestion and subsequent electrophoretic analysis. | 1994 | 7765449 |
| [campylobacter jejuni and hiv infection]. | to evaluate the characteristics of the campylobacter jejuni infection in hiv positive patients. | 1994 | 7912110 |
| flagellin gene polymorphism analysis of campylobacter jejuni infecting man and other hosts and comparison with biotyping and somatic antigen serotyping. | flagellin gene sequence polymorphisms were used to discriminate amongst 77 strains of campylobacter jejuni from sporadic and outbreak-associated human enteric infections, and from chickens, sheep and calves. the results were assessed in relation to lior biotyping and serotyping (penner somatic antigens). eight dna pcr-rflp patterns (genotypes) were identified by analysis of hinfi fragment length polymorphisms in flagellin gene (flaa) polymerase chain reaction (pcr) products. one genotype (f-1) w ... | 1994 | 7925661 |
| [toxic megacolon with colonic perforation complicating campylobacter jejuni ileo-colitis]. | campylobacter jejuni is an enteropathogen with invasive ability which may be responsible for acute colitis. we report the case of a 38-year-old woman who was hospitalized for severe acute colitis. stool specimen examination revealed campylobacter jejuni. a laparotomy was performed due to clinical deterioration and toxic megacolon. colic perforations were observed. the examination of the colectomy specimen revealed ulcerative pancolitis. this is the first published case of campylobacter jejuni in ... | 1994 | 7926445 |
| heat shock- and alkaline ph-induced proteins of campylobacter jejuni: characterization and immunological properties. | the protein response to physiological stress was characterized in campylobacter jejuni 81176 after exposure to heat and ph shock and following periods of recovery. immunoreactivities of major stress-related proteins were determined with anti-campylobacter immune rabbit serum and intestinal lavage fluid. distinct proteins with molecular masses ranging from 10 to 120 kda were induced and/or released by selective heat or ph treatments. the most notable responses were those of two proteins with appa ... | 1994 | 7927682 |
| mechanisms of quinolone resistance. | two mechanisms of resistance to fluoroquinolones are known: (i) alteration of the molecular target of quinolone action-dna gyrase, and (ii) reduction of the quinolone accumulation. mutations altering the n-terminus of the gyrase a subunit, especially those around residues ser83 and asp87, significantly reduce the susceptibilities towards all quinolones, while alterations of the gyrase b subunit are rarely found and are of minor importance. reduced drug accumulation is associated with alterations ... | 1994 | 7927834 |
| biodiversity of apidaecin-type peptide antibiotics. prospects of manipulating the antibacterial spectrum and combating acquired resistance. | insects have a unique repertoire of peptide antibiotics but, to date, prospects of clinical applications are not clear. apidaecin, a small peptide isolated from honeybees, inhibits viability of gram-negative bacteria; lethal activity is near immediate, independent of a conventional "lytic" mechanism, and involves stereoselective recognition of target molecules. here we report structural analysis of 14 naturally occurring apidaecin-type peptides and the existence of evolutionarily conserved ("con ... | 1994 | 7929322 |
| expression of a novel autoantibody defined by the vh3-15 gene in inflammatory bowel disease and campylobacter jejuni enterocolitis. | this study newly introduces anti-vh mabs to assess the role of clonal b cell activity in inflammatory bowel disease. immunohistochemistry of colonic biopsies in ulcerative colitis (uc) and crohn's disease (cd), but not unaffected individuals, demonstrated uniform staining of intravascular erythrocytes with bk2, a monoclonal specific for the vh3-15 ig heavy chain gene product. staining was caused by erythrocytes opsinized in vivo by anti-erythrocyte abs present in patient sera and by using the vh ... | 1994 | 7930592 |
| seroreactivity to campylobacter jejuni and gangliosides in patients with guillain-barré syndrome. | seroreactivities to campylobacter jejuni or campylobacter coli and to the gangliosides gm1 and gd1b were studied by quantitative and immunoglobulin class-specific elisas in 42 patients with recent onset of acute guillain-barré syndrome (gbs), in 39 patients with positive campylobacter serology but no neurologic disease, and in 52 healthy blood donors. gbs patients showed positive reactivities to c. jejuni in 57%, 26%, and 2% for igg, iga, and igm, respectively, while blood donors had correspondi ... | 1994 | 7930724 |
| development of a tissue culture assay system for campylobacter jejuni cytotoxin and the influence of culture conditions on cytotoxin production. | a tissue culture assay system to detect campylobacter jejuni cytotoxin was developed, and the effect of culture conditions on cytotoxin production was examined. broth-culture filtrates from clinical isolates were used. the expression of cytotoxicity was dependent on the presence of serum in the culture medium. although the titre of cytotoxin was low, the greatest cytotoxicity was revealed when newborn calf (ncs), adult bovine or goat serum was added to minimum essential medium. moderate or weak ... | 1994 | 7932615 |
| henoch-schönlein purpura associated with campylobacter jejuni enteritis. case report. | after an episode of enteritis caused by c. jejuni a 15-year-old boy developed schönlein-henoch purpura. because of continuous proteinuria a renal biopsy was performed. light microscopy revealed focal proliferative glomerulonephritis. iga was the dominant immunoglobulin. a causal relationship between enteritis caused by c. jejuni and schönlein-henoch purpura complicated with focal proliferative glomerulonephritis is suggested. | 1994 | 7939469 |
| [etiology, diagnosis and course of infectious diarrhea in the liestal canton hospital (5-year retrospective study)]. | between 1987 and 1991 219 patients (1.3% of all hospitalized patients) with acute infectious diarrhea were investigated retrospectively. 52% of the patients were hospitalized and 48% were outpatients. in 55% the inducing diarrhea microorganism could be identified. the most frequently detected pathogens were endemic salmonella sp. and campylobacter jejuni (65%). imported diarrheas (shigella sp. and parasites) were rare, as only 15% of the patients had a history of travel. all clostridium difficil ... | 1994 | 7939515 |
| clinical aspects of campylobacter jejuni infections in adults. | campylobacter jejuni is an almost ubiquitous, microaerophilic, gram-negative rod. outbreaks have been associated with drinking raw milk or contaminated water and eating poultry. campylobacter jejuni accounts for 3.2% to 6.1% of cases of diarrheal illness in the general population of the united states, and infected patients frequently present with abdominal pain and fever. less frequently, c jejuni is responsible for bacteremia, septic arthritis, septic abortion, and other extraintestinal infecti ... | 1994 | 7941533 |
| persistent, recurring diarrhea in a colony of orangutans (pongo pygmaeus) caused by multiple strains of campylobacter spp. | a colony of 10 orangutans (pongo pygmaeus) experienced persistent, recurring diarrhea caused by multiple infections with campylobacter jejuni and c. coli. infections appeared to have occurred through several mechanisms, including fecal-oral transmission between orangutans, and possibly transmission by houseflies contaminated with the organisms from nearby chicken feces. among the 14 fecal and environmental c. jejuni isolates, 4 different antibiotic susceptibility profiles were detected; there we ... | 1994 | 7942349 |
| [campylobacter gastroenteritis in patients with human immunodeficiency virus infection]. | campylobacter bacteria are frequent, and usually slight causes of diarrhea in a normal host while in an immunosuppressed host the diarrhea may lead to severe pictures. the aim of this study was to analyze the clinical features of gastroenteritis by campylobacter spp. in hospitalized seronegative patients and in those with hiv infection. | 1994 | 7948112 |
| [acute cholecystitis caused by campylobacter jejuni]. | 1994 | 7948125 | |
| [the endotoxins of gram-negative bacteria: their structure and biological role]. | main attention in the paper is paid to the study of lipid a, a component possessing endotoxic activity. lipids a containing glucosamine disaccharide (representatives of enterobacteriaceae family), and variants of lipid a differing from the toxic one either in the structure of carbohydrate core or in the spectrum of fatty acids are considered. they are either phototrophic, nodulating (bradyrhyzobium species) or soil species (nitrobacter and thiobacillus) bacteria. lipid a from lipopolysaccharides ... | 1994 | 7952230 |
| [a patient with guillain-barré syndrome in association with campylobacter jejuni enteritis (pen19:lio7) in a patient with hla-b52 antigen]. | we report a 15-year-old boy with guillain-barré syndrome (gbs) in association with campylobacter jejuni enteritis. a neurologic examination revealed distal-dominant weakness and areflexia. compound muscle action potentials were markedly reduced in amplitude, but the decrease in motor conduction velocities was slight. c. jejuni was isolated from his stool culture and the serotype belonged to pen19:lio7. thin-layer chromatography-immunostaining showed that his serum igg reacted strongly with gm1 a ... | 1994 | 7955736 |
| severe campylobacter jejuni diarrhoea in a patient with hodgkin's disease. | 1994 | 7963346 | |
| [unusual forms of bacteremia due to campylobacter jejuni in patients with hiv infection]. | 1994 | 7967876 | |
| reproduction of proliferative enteritis in hamsters with a pure culture of porcine ileal symbiont intracellularis. | hamsters, three weeks old, were inoculated orally with suspensions of intracellular bacteria, grown in tissue culture cells, iec-18, rat enterocytes. cells had been infected with suspensions of intracellular bacteria derived from the lesions of proliferative haemorrhagic enteropathy occurring naturally in two pigs 916/91 and 1482/89. infected cell lines containing each separate strain, 916/91 and 1482/89, were passaged one, two or five times and pure cultures of intracellular bacteria, identifie ... | 1994 | 7801512 |
| experimental colonization of mice with campylobacter jejuni. | the ability of one human and two chicken strains of campylobacter jejuni to colonise and survive in three different strains of laboratory mice (nmri, cba and c57-black) was studied. mice were inoculated orally with campylobacter jejuni and faeces samples were cultured at regular intervals during the following months. the length of colonisation of mice differed between mouse strains but also between campylobacter strains. the mouse strain c57-black was not colonised with c. jejuni to the same deg ... | 1994 | 7801521 |
| guillain-barré syndrome. | guillain-barré syndrome has now become recognized as a clinical syndrome that may be due to several pathological entities, consisting of an acute inflammatory demyelinating polyradiculoneuropathy as well as an acute motor axonal neuropathy. campylobacter jejuni infection is a common preceding event and, together with anti-ganglioside gm1 antibodies, is associated with axonal damage and a poor outcome. the mechanism by which such antibodies damage axons is not clear. the miller fisher syndrome is ... | 1994 | 7804457 |
| development of resistance to macrolide antibiotics in an aids patient treated with clarithromycin for campylobacter jejuni diarrhea. | in an aids patient with diarrhea, identical isolates of campylobacter jejuni susceptible and, later, resistant to macrolide antibiotics were isolated from feces before and after treatment with clarithromycin. results of rrna gene restriction analysis and serotyping suggest that development of resistance rather than simultaneous infection with a susceptible and a resistant strain was responsible for this phenomenon. this is the first report of in vivo development of resistance by campylobacter je ... | 1994 | 7805694 |
| campylobacter jejuni infection and the guillain-barre syndrome: mechanisms and implications. | 1994 | 7727903 | |
| antimicrobial susceptibility and plasmid analysis of campylobacter jejuni isolated from diarrhoeal patients and healthy chickens in northern india. | seventy-five strains of campylobacter jejuni isolated from humans with diarrhoea (45 strains) and healthy chickens (30 strains) were tested for their susceptibility to different antimicrobial agents: ampicillin, tetracycline, erythromycin, gentamicin, kanamycin, furazolidine and quinolones (nalidixic acid, norfloxacin, ciprofloxacin). the frequencies of resistance to ampicillin and tetracycline were 16 and 9.3% respectively. two strains (2.7%) exhibited resistance to quinolones as mentioned. one ... | 1994 | 7751568 |
| food and animal sources of human campylobacter jejuni infection. | 1994 | 8125823 | |
| bacteraemia caused by campylobacter spp. | the genus campylobacter has become increasingly recognised as the cause of various infections. campylobacter jejuni and c coli cause acute gastroenteritis in man all over the world. c jejuni enteritis can lead to bacteraemia, but its actual incidence remains unknown. seven cases of bacteraemia caused by c jejuni or c coli are reported, from the blood of seven patients: five immune deficient adults; a newborn baby; and a patient who had had abdominal surgery. patients who develop diarrhoea as a r ... | 1994 | 8132835 |
| etiology of diarrhea in a rural community in western thailand: importance of enteric viruses and enterovirulent escherichia coli. | the etiology of gastroenteritis was determined in children and adults with diarrhea seen at a district hospital and three government health clinics in suan phung, western thailand, in 1991. enteric viruses (rotavirus and astrovirus) were identified in 40%, shigellae in 18%, attaching and effacing escherichia coli in 13%, campylobacter jejuni in 9%, and enterotoxigenic e. coli in 7% of children < 5 years old with diarrhea seen at the hospital. enteric viruses were detected in 15% (24/156) of pati ... | 1994 | 8133110 |
| campylobacter jejuni enterocolitis causing peritonitis, ileitis and intestinal obstruction. | patients with campylobacter enterocolitis may come to laparotomy due to the severity of abdominal symptoms and signs, although only two patients with intestinal inflammation have been described and in neither was the histopathology documented. a case of a 52-year-old male who had a typical diarrhoeal illness of campylobacter enterocolitis diagnosed on stool culture is reported. despite appropriate treatment he developed signs and symptoms consistent with small intestinal obstruction. laparotomy ... | 1994 | 8267541 |
| gm 1 antibodies in guillain-barré syndrome: isotypes, course and clinical outcome. | iga, igg, and igm antibodies against ganglioside gm 1 were investigated in sera of 15 patients with guillain-barré syndrome (gbs), as compared with healthy controls. significantly raised titers were found in 4 patients who showed persisting weakness due to muscle wasting (3 patients) or due to the development of a chronic relapsing form of gbs (1 patient) after a follow up period of 1 year. by contrast, only 1 out of 11 anti-gm 1 seronegative patients showed persisting muscle wasting. in 1 patie ... | 1994 | 8197746 |
| campylobacter jejuni bacteremia and guillain-barré syndrome in a patient with gvhd after allogeneic bmt. | guillain-barré syndrome is a rare neurologic complication after allogeneic bmt. in the non-transplant setting, guillain-barré syndrome has typically been associated with antecedent acute infections and numerous reports have suggested an association between campylobacter jejuni infection and the subsequent development of guillain-barré syndrome. thus far, however, reports of c. jejuni-associated guillain-barré syndrome have been limited to gastrointestinal c. jejuni infections and none has been r ... | 1994 | 8199580 |
| [the role of flagella of campylobacter jejuni in colonization in the intestinal tract in mice and the cultured-cell infectivity]. | for analyzing the role of the bacterial flagella in colonization in the intestinal tract of mice and adhering to or invading the intestine 407 cell, a nonflagellated, nonmotile mutant was induced by ultraviolet irradiation of a flagellated, motile wild-type strain of campylobacter jejuni cf84-340. there was no great difference in the cellular infectivity to the intestine 407 cells between the wild-type and the mutant strains. cellular adherence and invasiveness were then compared by fluorescent ... | 1994 | 8201772 |
| monoclonal igm antibodies to gm1 and asialo-gm1 in chronic neuropathies cross-react with campylobacter jejuni lipopolysaccharides. | we tested monoclonal igm anti-gm1 and asialo-gm1 antibodies from 6 patients with chronic motor neuropathies for binding to lipopolysaccharides (lps) from three stains of campylobacter jejuni. four of the 6 patients showed strong reactivity with lps from at least one of the three c. jejuni strains tested as shown by enzyme-linked immunosorbent assay or western blot. preabsorption with gm1 or asialo-gm1, or blocking with cholera toxin, prevented antibody binding to lps. these studies indicate that ... | 1994 | 8210226 |
| lipopolysaccharides of campylobacter jejuni serotype o:19: structures of core oligosaccharide regions from the serostrain and two bacterial isolates from patients with the guillain-barré syndrome. | lipopolysaccharides from phenol-water extraction of cells of campylobacter jejuni serotype o:19 were separated into a water-soluble gel of low m(r) and a water-soluble component of high m(r). acetic acid hydrolysis of the ketosidic linkages to lipid a furnished respectively a core oligosaccharide, the structure of which is reported herein, and an o antigenic polysaccharide. structural investigations were performed on the o-deacetylated lipopolysaccharide of low m(r), the liberated core oligosacc ... | 1994 | 8286348 |
| development and characterization of reca mutants of campylobacter jejuni for inclusion in attenuated vaccines. | isogenic reca mutants of campylobacter jejuni have been constructed for evaluation of their usefulness in attenuated vaccines against this major worldwide cause of diarrhea. the reca+ gene of c. jejuni 81-176 was cloned by using degenerate primers to conserved regions of other reca proteins in a pcr. the c. jejuni reca+ gene encodes a predicted protein with an m(r) of 37,012 with high sequence similarity to other reca proteins. the termination codon of the reca+ gene overlaps with the initiation ... | 1994 | 8300203 |
| intestinal b cell defects in common variable immunodeficiency. | the humoral immune system of the small intestine of 17 patients with common variable immunodeficiency (cvid) was studied by immunohistology using antibodies specific for iga1,2, igm, igg1-4, the j chain and the secretory component (sc). iga1,2+, igg2+ and igm+ lamina propria b cells were totally lacking in 65% (11/17), 41% (7/17) and 18% (3/17) of cvid patients, respectively. one patient exhibited an isolated iga1 subclass deficiency. the proportion of plasma cells in conventionally stained hist ... | 1994 | 8306494 |
| guillain-barré syndrome with severe persistent disability: relationship to hyperacute guillain-barré syndrome. | guillain-barré syndrome (gbs) is a heterogeneous condition with a variable prognosis. we studied nine patients who were unable to walk unaided 12 months after the onset of their illness to discover whether they belonged to a more homogeneous subgroup. sis of the nine patients had symptoms of gastroenteritis shortly before the onset of their neuropathic symptoms and a hyperacute onset of weakness so that they were bed-bound within 24 h. these patients had predominantly motor rather than sensory i ... | 1994 | 24283425 |
| changes in cell morphology and polyamine composition during growth of campylobacter jejuni. | resting cells of campylobacter jejuni were spherical whereas growing cells were mainly spiral. content of cadaverine increased with the decrease in spherical forms prior to growth commencing but production of spermidine increased in early log phase. cadaverine and spermidine are possibly involved in changes in cell morphology and growth, respectively. | 1994 | 24421028 |
| ph and acidity in lactic-fermenting cereal gruels: effects on viability of enteropathogenic microorganisms. | survival of bacillus cereus, campylobacter jejuni, enterotoxigenic escherichia coli, salmonella typhimurium and shigella flexneri during lactic acid fermentation of cereal gruels prepared from low-tannin (white) and high-tannin (red) sorghum varieties was studied. a previously fermented gruel (starter culture, sc) recycled daily or stored for 7, 14 or 28 days, germinated cereal flour (power flour, pf), or a combination of pf and sc (pf+sc) were used as starters. at 24 h, the ph of all gruels wit ... | 1994 | 24421191 |
| the microbiology of acute diarrhoeal disease in the eastern province of saudi arabia. | a prospective study of acute diarrhoeal diseases in the eastern province of saudi arabia was carried out over a 19-month period to determine aetiology, risk factors and other epidemiological characteristics. of the 853 subjects studied, 344 were cases and 509 controls. more cases were seen in children than in adults. enteric pathogens were detected in 49% of the cases, but none in the controls. of the pathogens, 68% were bacterial with salmonella (34%) and shigella species (14.7%) being the most ... | 1993 | 8306900 |
| use of an immunoglobulin m containing preparation for treatment of two hypogammaglobulinemic patients with persistent campylobacter jejuni infection. | this report describes two hypogammaglobulinemic patients with persistent campylobacter jejuni infections in spite of igg substitution and antibiotic therapy. since serum bactericidal activity (sba) depends on igm, these patients were each treated with six doses of an igm-containing immunoglobulin preparation (pentaglobin) at three-week intervals. during igg therapy sba was not seen in either patient. however, one hour following administration of the igm preparation, sba increased to 90%. just be ... | 1993 | 8307048 |
| diarrhea in u.s. troops deployed to thailand. | ninety-five (28%) of 333 u.s. military personnel deployed to ubonratchathani, thailand, for 1 month in february 1993 developed diarrhea. campylobacter jejuni was identified in 6 (25%), attaching and effacing escherichia coli was identified in 3 (13%), nontyphoidal salmonella spp. were identified in 2 (8%), and rotavirus was identified in 1 (4%) of 24 persons who had diarrhea and submitted specimens. | 1993 | 8308137 |
| development of species-specific dna probes for campylobacter jejuni, campylobacter coli, and campylobacter lari by polymerase chain reaction fingerprinting. | the application of polymerase chain reaction (pcr) fingerprinting assays enables discrimination between species and strains of microorganisms. pcr primers aiming at arbitrary sequences in combination with primers directed against the repetitive extragenic palindrome (rep) or enterobacterial repetitive intergenic consensus (eric) motifs generate isolate-specific dna banding patterns. analysis of these pcr fingerprints obtained for 33 isolates of campylobacter jejuni, 30 isolates of campylobacter ... | 1993 | 8314996 |
| plasma level of antisecretory factor (asf) and its relation to post-weaning diarrhoea in piglets. | antisecretory factor (asf) is a regulatory peptide which counteracts diarrhoea in the pig; asf is rapidly absorbed from the pig intestine, and significantly reduces the incidence of neonatal diarrhoea in the suckling offspring. asf is synthesized in the central nervous system, and released to the blood stream via the pituitary gland. in two different experiments (n = 8 and n = 4), the blood concentration of asf was followed in 5-weeks old piglets from day 7 before weaning up to day 12 days after ... | 1993 | 8322543 |
| isolation and characterization of two campylobacter glycine-extracted proteins that bind to hela cell membranes. | two immunogenic proteins of 27 (cbf1) and 29 (cbf2) kda from enteropathogenic campylobacter species appear to bind to mammalian cells. we purified these two proteins from a pathogenic and adherent campylobacter jejuni strain to homogeneity by using acid extraction, preparative gel electrophoresis, and electroelution. polyclonal rabbit antisera to these proteins were prepared. immunologic studies indicate that cbf1 corresponds to the peb1 and cbf2 corresponds to the peb4 described by pei et al. ( ... | 1993 | 8335374 |
| newborn piglet model for campylobacteriosis. | an in vivo model system for human campylobacteriosis has been developed in which colostrum-deprived newborn piglets are orally challenged with an invasive strain of campylobacter jejuni. piglets developed clinical symptoms and histopathological lesions similar to those observed in humans infected with c. jejuni. gross lesion examination at autopsy revealed the presence of edema, hyperemia, and mucus. histopathologic examinations by light and transmission electron microscopy demonstrated damage t ... | 1993 | 8335377 |
| serum antibodies to gm1, gd1b, peripheral nerve myelin, and campylobacter jejuni in patients with guillain-barré syndrome and controls: correlation and prognosis. | serum antibodies to monosialoganglioside (gm1), disialoganglioside (gd1b), and campylobacter jejuni, measured by enzyme-linked immunosorbent assay and serum antibodies to peripheral nerve myelin, measured by the c1 fixation and transfer assay, were studied in 58 acute-phase patients with guillain-barré syndrome (gbs), 42 disease controls, and 29 normal controls. anti-peripheral nerve myelin antibodies were elevated in 57 of 58 patients with gbs compared with controls, whereas only 8.6% had incre ... | 1993 | 8338337 |
| the spectrum of immune responses to campylobacter jejuni and glycoconjugates in guillain-barré syndrome and in other neuroimmunological disorders. | an acute infectious illness frequently precedes the guillain-barré syndrome. recently, campylobacter jejuni was claimed to be a predominant precipitating agent that may also trigger a humoral immune response to glycoconjugates of peripheral myelin in guillain-barré syndrome. because of conflicting reports, we determined the frequency of a recent infection with c. jejuni in 38 patients with guillain-barré syndrome using a highly sensitive and specific immunoblot technique, and of the presence of ... | 1993 | 8338338 |
| cloning and characterization of the gamma-glutamyl phosphate reductase gene of campylobacter jejuni. | the gamma-glutamyl phosphate reductase gene, proa, of campylobacter jejuni was isolated from a recombinant pbr322 clone. a hindiii fragment of the insert containing the gene was subcloned into puc19 and sequenced in both orientations. the deduced amino acid sequence of gamma-glutamyl phosphate reductase (ec 1.2.1.41) of c. jejuni exhibits 36.4% identity to that of escherichia coli and 36.0% identity to serratia marcescens. two highly conserved regions in the amino acid sequence were identified f ... | 1993 | 8341262 |
| unusual microtubule-dependent endocytosis mechanisms triggered by campylobacter jejuni and citrobacter freundii. | bacterial invasion of six different human epithelial cell lines showed that some strains of the intestinal pathogen campylobacter jejuni invaded intestinal cell lines at a level 10(2)-10(4) times higher than reported previously for other campylobacter strains. separately, urinary tract isolates of citrobacter freundii triggered a high-efficiency invasion of bladder cells. use of multiple inhibitors with known effects on eukaryotic cell structures/processes allowed us to define in these genetical ... | 1993 | 8341714 |
| enterotoxigenic bacteria in the sudden infant death syndrome. | faecal samples from 123 infants who died with sudden infant death syndrome (sids) and from a comparative group of 52 age-matched babies were analysed for toxigenic bacteria and their toxins. serum samples from the sids infants were also analysed for these toxins. a significantly higher proportion of toxigenic bacteria and their toxins were found in faecal samples of sids babies than in samples from the comparative group. these toxins were also found in serum from the sids babies. clostridium per ... | 1993 | 8345506 |
| common diarrhea pathogens and the risk of dehydration in young children with acute watery diarrhea: a case-control study. | the role of common diarrheal pathogens in dehydration was examined in children with acute watery diarrhea who attended the treatment center of the international centre for diarrhoeal disease research, bangladesh, in dhaka. two hundred sixty-nine children with moderate or severe dehydration were matched with 700 children with no dehydration. vibrio cholerae o1 infections were 5.5 times more likely to be associated with dehydration than in cases without this agent. no significant association could ... | 1993 | 8352397 |
| role of infection due to campylobacter jejuni in the initiation of guillain-barré syndrome. | recent reports suggest that infection with campylobacter jejuni, a common enteric pathogen, may cause guillain-barré syndrome (gbs) by triggering demyelination of peripheral nerves. gbs is preceded by an acute infectious illness (due to a variety of agents) in 50%-75% of cases; the onset of neurological symptoms is preceded by diarrhea in 10%-30% of cases. in the last decade, more than 20 published anecdotal reports and case series have described patients with c. jejuni infection documented 1-3 ... | 1993 | 8353228 |
| cholecystitis caused by campylobacter jejuni. | 1993 | 8353233 | |
| [campylobacter jejuni sepsis and chronic terminal kidney insufficiency]. | 1993 | 8355552 | |
| direct polymerase chain reaction detection of campylobacter jejuni and campylobacter coli in raw milk and dairy products. | a polymerase chain reaction (pcr) method designed to sensitively detect and identify campylobacter jejuni and campylobacter coli without the need for isolating and culturing strains is described. the intergenic sequence between the flagellin genes flaa and flab was amplified and characterized with a triple primer or seminested primer approach. a total of 50 bacterial strains, 27 of c. jejuni and c. coli and 23 of other species, were tested, giving no false-positive or false-negative results. the ... | 1993 | 8357250 |
| peb1, the major cell-binding factor of campylobacter jejuni, is a homolog of the binding component in gram-negative nutrient transport systems. | the protein peb1 (28 kda) is a common antigen and a major cell adherence molecule of campylobacter jejuni and campylobacter coli. we created a bank of chromosomal dna fragments of c. jejuni strain 81-176 using lambda gt11. screening this bank in escherichia coli y1090 cells with antibody raised against purified peb1 enabled us to isolate and to purify a clone with a 2.6-kilobase insert expressing an immunoreactive protein of 28 kda. dna sequencing revealed that the insert contains three complete ... | 1993 | 8360165 |
| colonization of chicks by motility mutants of campylobacter jejuni demonstrates the importance of flagellin a expression. | campylobacter jejuni strain 81116 contains two flagellin genes, flaa and flab. wild-type (wt) bacteria express flaa only, but flab can be expressed under certain conditions. we have determined the importance of flagella for colonization of the avian caecum, which appears to be the natural environment for these bacteria. mutants in which flaa or flab, or both had been inactivated, and motility variants, were investigated. flagella are not a requisite for colonization, but mutants lacking both fla ... | 1993 | 8360610 |
| a cytotoxicity test for the detection of campylobacter jejuni toxin. | a 7-h 51cr-release cytotoxicity assay has been developed to detect the presence of campylobacter jejuni toxin in the culture supernatant. some of the culture supernatants have cytotoxic effects against labeled chicken lymphocytes, while some others do not have this effect. there is no direct correlation between the pathogenicity of the organisms and the presence of the toxin. the supernatant of c. jejuni retains its cytotoxicity after heating at 100 degrees c for 10 min.; therefore, it is a heat ... | 1993 | 8362493 |
| pulsed-field gel electrophoretic analysis of campylobacter jejuni dna for use in epidemiological studies. | the cleavage patterns of the genomic dna of 42 clinical isolates of campylobacter jejuni determined by pulsed-field gel electrophoresis (pfge) were compared with their lior and tck serotypes. the fragment patterns of dna obtained with sali and smai restriction enzymes did not always accord with the corresponding serotypes but strains of the same serotype could be further divided into subtypes by their cleavage patterns. this pfge method may prove useful for subclassifying c. jejuni. | 1993 | 8370943 |
| application of polymerase chain reaction for the correlation of salmonella serovars recovered from greyhound feces with their diet. | the polymerase chain reaction was employed to correlate salmonella serovars isolated from fecal material of greyhounds suffering from gastroenteritis with those isolated from the diet fed to the greyhounds prior to onset of diarrhea. kennels around the abilene, kansas, area were contacted and supplied with materials needed to collect a portion of the diet each day. with the onset of diarrhea, the kennels were instructed to ship the fecal material and diet from the previous 10 days to the laborat ... | 1993 | 8373851 |
| kinetic and antigenic characterization of altered protein synthesis by campylobacter jejuni during cultivation with human epithelial cells. | cultivation of campylobacter jejuni with int 407 cell monolayer cultures results in new or enhanced synthesis of a number of proteins compared with bacteria cultured in the absence of the epithelial cells. these proteins were detected within 60 min after the addition of the bacteria to the epithelial cell cultures, and their synthesis was temporally associated with an increase in c. jejuni internalization. a rabbit antiserum raised against bacteria that were cultivated with int 407 cells recogni ... | 1993 | 8376841 |
| tales of campylobacter jejuni. | 1993 | 8379884 | |
| helicobacter acinonyx sp. nov., isolated from cheetahs with gastritis. | four strains of a novel helicobacter species were isolated from the stomachs of cheetahs (acinonyx jubilatus) with gastritis. these isolates were phenotypically similar to helicobacter pylori. the isolates were gram-negative, spiral bacteria which grew under microaerophilic conditions at 37 degrees c, but not at 25 or 42 degrees c, and produced urease, catalase, oxidase, alkaline phosphatase, and gamma-glutamyl transpeptidase. the isolates did not ferment glucose, mannitol, inositol, sorbitol, r ... | 1993 | 8379970 |
| rotavirus-inhibitory activity in serial milk samples from mexican women and rotavirus infections in their children during their first year of life. | a total of 75 children born in rural mexico were followed for diarrheal diseases and rotavirus (rv) excretion during the first year of life. for 18 children, an average of 14 serial breast milk samples were obtained between days 2 and 360 after delivery and were tested for rv-inhibitory activity. of these samples, 70, 62, and 85% showed inhibitory activity against serotype (st) 1 human rv, st4 human rv, and st3 simian rv, respectively; the median titers were 10, 10, and 20, respectively. some 89 ... | 1993 | 8384626 |
| cloning and nucleotide sequence of the campylobacter jejuni gyra gene and characterization of quinolone resistance mutations. | the gyra gene of campylobacter jejuni ua580, which encodes the a subunit of dna gyrase, was cloned and its nucleotide sequence was determined. an open reading frame of 2,589 nucleotides was identified, which could code for a polypeptide of 863 amino acids with a m(r) of 97 kda. both the nucleotide sequence and the putative amino acid sequence show ca. 50% identity with those of other gyra genes from gram-positive and gram-negative bacteria. the locations of the gyra gene on genome maps of both c ... | 1993 | 8384814 |
| chemical structures of the core regions of campylobacter jejuni serotypes o:1, o:4, o:23, and o:36 lipopolysaccharides. | 1993 | 8404908 | |
| isolation of campylobacter jejuni strains resistant to nalidixic acid and fluoroquinolones from children with diarrhea in athens, greece. | 1993 | 8404924 | |
| studies on the pathophysiological mechanism of campylobacter jejuni-induced fluid secretion in rat ileum. | calcium has been reported to play an important role in regulating the intestinal electrolyte transport via ca2+/calmodulin (cam) and/or protein kinase c (pkc) systems. the role of ca2+, cam and pkc in the pathogenesis of campylobacter jejuni-induced fluid accumulation was studied in vivo in ligated rat ileal loops. calcium ionophore a23187 (5 microm) and pkc activator, phorbol-12-myristate-13-acetate (pma, 100 micrograms kg-1) when injected alone induced fluid accumulation in the control loops. ... | 1993 | 8405940 |
| genetic manipulation of campylobacter: evaluation of natural transformation and electro-transformation. | two methods, natural transformation and electro-transformation, for the introduction of dna into nine strains of campylobacter jejuni were compared. both methods were successful with a limited number of strains. natural transformation was efficient only for the introduction of c. jejuni chromosomal dna, while electro-transformation was also applicable for the introduction of escherichia coli-derived vector dna into at least one c. jejuni strain. the efficiency of dna recombination after entry wa ... | 1993 | 8406035 |
| roles of leukotriene b4, prostaglandin e2, and cyclic amp in campylobacter jejuni-induced intestinal fluid secretion. | infection of rabbit ileal loops with inflammatory campylobacter jejuni strains caused elevation of cyclic amp, prostaglandin e2, and leukotriene b4 levels in tissue and fluids. incubation of cultured caco-2 cells with loop fluids caused elevated cellular cyclic amp levels, an effect which was inhibited by antiserum against prostaglandin e2. | 1993 | 8406889 |
| antibiosis revisited: bacteriocins produced by dairy starter cultures. | well before the existence of starter bacteria was recognized, their activities were instrumental in preserving dairy foods. during growth in fermented products, dairy starters, including lactobacilli, lactococci, leuconostocs, streptococci, and propionibacteria, produce inhibitory metabolites. inhibitors include broad-spectrum antagonists, organic acids, diacetyl, and hydrogen peroxide. some starters also produce bacteriocins or bactericidal proteins active against species that usually are relat ... | 1993 | 8408870 |
| the effect of slurry storage and anaerobic digestion on survival of pathogenic bacteria. | the decline in viable numbers of salmonella typhimurium, yersinia enterocolitica and listeria monocytogene in beef cattle slurry is temperature-dependent; they decline more rapidly at 17 degrees c than at 4 degrees c. mesophilic anaerobic digestion caused an initial rapid decline in the viable numbers of escherichia coli, salm. typhimurium, y. enterocolitica and l. monocytogenes. this was followed by a period in which the viable numbers were not reduced by 90%. the t90 values of e. coli, salm. t ... | 1993 | 8420921 |
| campylobacter jejuni adapts to aerobic metabolism in the environment. | campylobacter jejuni, when left on blood agar for prolonged periods, was found to survive better in air than under micro-aerobic conditions. after a period of 2-3 days in air, all strains of c. jejuni examined grew freely in air on subculture, and could be further subcultured apparently indefinitely in air. this adaptation to aerobic metabolism was accompanied by a change in colony morphology and some changes in outer-membrane protein patterns, but no change in serotyping reactions. the ability ... | 1993 | 8429540 |
| detection of enterovirulent escherichia coli associated with diarrhoea in seville, southern spain, with non-radioactive dna probes. | to assess the role of diarrhoeagenic escherichia coli in southern spain, faecal samples from 135 patients with diarrhoea and 40 healthy subjects from seville, andalusia, were investigated. in this prospective study, enterovirulent e. coli were identified by hybridisation with five non-radioactive dna probes specific for enterotoxigenic e. coli (etec), enteropathogenic e. coli (epec) and verocytotoxin-producing e. coli (vtec). probe-positive strains were isolated from four patients (3%) with diar ... | 1993 | 8429544 |
| frequency and enterotoxigenicity of campylobacter jejuni and c. coli in domestic animals in pakistan as compared to sweden. | domestic and wild animals have been considered to be the most common reservoirs of campylobacter for human infections. this study has been conducted to establish the frequency and enterotoxigenicity of c. jejuni and c. coli in the stools of domestic animals in a developing versus a developed country. faecal samples of 300 chickens and laying hens, 102 horses, 180 cows, 92 goats and sheep were collected from pakistan and sweden. the hippurate hydrolysis test and cho-cell test were performed for s ... | 1993 | 8429572 |
| factors influencing fecal shedding of campylobacter jejuni in dogs without diarrhea. | rectal swab specimens were collected from 362 apparently healthy dogs of different origin, age, breed, and sex. specimens were obtained in summer, autumn, and winter. ninety-five thermophilic campylobacter spp were isolated: c jejuni biotype i, n = 57, c jejuni biotype ii, n = 1, c coli, n = 36, and c laridis, n = 1. biotypes of c jejuni recovered were the same as those associated with campylobacter-induced enteritis in human beings. prevalence of c jejuni was significantly (p < 0.05) greater: i ... | 1993 | 8430936 |
| the role of exposure to animals in the etiology of campylobacter jejuni/coli enteritis. | to determine the role of animals as possible sources for human infection with campylobacter jejuni/coli, 218 human cases of campylobacter enteritis diagnosed among members of group health cooperative of puget sound, king county, washington, from april 1982 through september 1983 were compared with 526 controls, randomly selected from group health cooperative members. all subjects were questioned regarding animal exposures one week prior to illness (cases) or interview (controls). there was no in ... | 1993 | 8434569 |
| [campylobacter jejuni infection in the neonatal period. a potentially serious condition]. | 1993 | 8439109 | |
| [prevalence of enteropathogenic bacteria in children with acute bloody diarrhea]. | between january to october 1991, were studied 148 samples of feces corresponding to the same number of children with acute diarrhea. in 41 (27.7%) samples, were found macroscopic or microscopic blood. at least one associated bacterial pathogen capable to produce bloody diarrhea was isolated from 22 (53.7%) of these samples. were isolated five (12.2%) salmonella strains, all of them were s. enteritidis; nine (22.0%) shigella: seven s. flexneri, one s. boydii, and other one s. sonnei; two (4.9%) e ... | 1993 | 8442878 |
| multiple antibiotic resistance in a strain of campylobacter jejuni acquired in jordan. | 1993 | 8444665 | |
| prosthetic hip infection and bacteremia due to campylobacter jejuni in a patient with aids. | campylobacter jejuni is a common enteric pathogen in healthy individuals and in patients with aids. it usually causes a self-limited diarrheal illness with fever and abdominal pain. we report what we believe is a unique case of c. jejuni osteomyelitis in a 60-year-old man who had hemophilia a, aids, and a hip prosthesis. he presented to the hospital with a 4-day history of fever and diarrhea and a 1-day history of hip pain. findings on plain films and a bone scan were suggestive of osteomyelitis ... | 1993 | 8452956 |
| effect of host lineage on the virulence of campylobacter jejuni/coli in the chick embryo model. | the chorioallantoic membrane (cam) inoculated chick embryo model was used to study the effect of host lineage on the virulence of campylobacter jejuni and campylobacter coli. ld50 values were used to compare the susceptibilities of chick embryos from eight inbred chicken lines to infection by four strains of c. jejuni and one strain of c. coli. differences in susceptibility were found between inbred chicken lines. these were shown not to be due to maternal antibody status, nor transfer of antibo ... | 1993 | 8454192 |
| postinfectious encephalopathy in a child following campylobacter jejuni enteritis. | we report a case of acute postinfectious encephalopathy in a child following campylobacter jejuni enteritis. serial mr scans showed lesions involving predominantly gray matter and the adjacent subcortical white matter--findings different from those in other immune-mediated disorders, such as systemic lupus erythematosus, in which either white or gray matter may be involved, and acute disseminated encephalomyelitis, in which white matter abnormalities predominate with involvement of the subcortic ... | 1993 | 8456726 |
| [bacteremia caused by campylobacter jejuni resistant to nalidixic acid and fluoroquinolones]. | 1993 | 8461378 | |
| in vitro susceptibility of quinolone-resistant campylobacter jejuni to new macrolide antibiotics. | the mics of erythromycin and three new macrolide antibiotics were determined for 36 quinolone-susceptible and 106 quinolone-resistant campylobacter jejuni. the mic90 values of azithromycin, clarithromycin, roxithromycin and erythromycin were 0.5, 4, 16 and 4 mg/l respectively. no difference was found between macrolide activity against the quinolone-susceptible and the quinolone-resistant strains. clarithromycin and especially azithromycin might eventually replace erythromycin for the treatment o ... | 1993 | 8462563 |
| evaluation of commercial antisera for serotyping heat-labile antigens of campylobacter jejuni and campylobacter coli. | commercial antisera for serotyping 22 heat-labile antigens of campylobacter jejuni and campylobacter coli were evaluated by using 66 isolates from human and nonhuman sources. test results were compared with results of tests using antisera produced at the centers for disease control (cdc), atlanta, ga. all strains (three isolates of each of the 22 serotypes) were typeable with the cdc antisera. of 66 test strains, 39 (59%) were typed as the same serotype with both sets of antisera. twenty-four st ... | 1993 | 8463402 |