Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| relationship of adverse events to serum drug levels in patients receiving high-dose azithromycin for mycobacterial lung disease. | we treated 39 elderly human immunodeficiency virus-noninfected patients with mycobacterium avium complex and/or mycobacterium abscessus lung disease with azithromycin (600 mg daily), given initially as monotherapy. adverse events occurred in 33 of 39 patients (85%) receiving azithromycin alone, most commonly gastrointestinal (gi) symptoms (32 of 39, or 82%) and hearing impairment (10 of 39, or 26%). twenty-four of 39 patients (62%) required a lower dose or withdrawal of the drug. the mean serum ... | 1997 | 9142801 |
| cutaneous infection due to mycobacterium abscessus. a case report. | erythematous nodular and ulcerating skin lesions occurred in a 56-year-old woman treated with chemotherapy and glucocorticosteroids for metastatic breast cancer. subsequent culture yielded mycobacterium abscessus, a facultative pathogen which exists as a saprophyte in the environment and rarely produces clinical disease in humans. this organism is usually relatively resistant to antituberculous as well as a number of other antimicrobial agents. on the basis of in vitro susceptibility results, tr ... | 1997 | 9188876 |
| report on an outbreak of postinjection abscesses due to mycobacterium abscessus, including management with surgery and clarithromycin therapy and comparison of strains by random amplified polymorphic dna polymerase chain reaction. | an outbreak of postinjection abscesses occurred in barranquilla, colombia, and was associated with local injections of lidocaine given in a single physician's office. over a 5-month period, 350 (18%) of approximately 2,000 injected patients developed localized cutaneous abscesses or cellulitis; of 210 abscess specimens that were cultured, 205 were positive for rapidly growing mycobacteria, subsequently identified as mycobacterium abscessus. the source of the outbreak was not identified. m. absce ... | 1997 | 9195073 |
| nontuberculous mycobacteria isolates: clinical significance and disease spectrum. | the incidence of diseases caused by nontuberculous mycobacteria (ntm) is increasing worldwide. there has been no previous report regarding the clinical significance and disease spectrum of these bacteria in taiwan. from january 1992 to june 1996, 201 isolates of ntm were recovered from clinical specimens from 143 patients at national taiwan university hospital. we retrospectively studied the clinical records and radiographs of these patients. a total of 86 isolates of ntm were considered clinica ... | 1997 | 9290272 |
| iatrogenic mycobacterium abscessus infection: histopathology of 71 patients. | the histopathology is described of 190 skin biopsies from 71 patients who presented during an epidemic of nodules and abscesses in the periumbilical region and buttocks, secondary to the application of xylocaine injections. positive cultures for mycobacterium abscessus were obtained from the specimens and from the xylocaine solution. the severe inflammatory lesions involved the dermis and the hypodermis and had three main histopathological patterns: (i) granulomatous nodular or diffuse inflammat ... | 1997 | 9292069 |
| rapid identification of mycobacteria to the species level by polymerase chain reaction and restriction enzyme analysis--a case report of corneal ulcer. | we report a case of corneal ulcer caused by nontuberculous mycobacteria which was confirmed by smear and culture. we attempted a new method for the rapid identification of mycobacteria to the species level on the basis of evaluation by the polymerase chain reaction of the gene encoding. the method is involved with restriction enzyme analysis of pcr product obtained with primers common to all mycobacteria. using the restriction enzyme bst eii and hae iii, clinically relevant and other frequent la ... | 1997 | 9348738 |
| strategies used by pathogenic and nonpathogenic mycobacteria to synthesize rrna. | one rrna operon of all mycobacteria studied so far is located downstream from a gene thought to code for the enzyme udp-n-acetylglucosamine carboxyvinyl transferase (unacgct), which is important to cell wall synthesis. this operon has been designated rrnaf for fast-growing mycobacteria and rrnas for slow growers. we have investigated the upstream sequences and promoter activities of rrna operons of typical fast growers which also possess a second rrn (rrnbf) operon and of the rrna operons of the ... | 1997 | 9371439 |
| collection of three bacterial aerosols by respirator and surgical mask filters under varying conditions of flow and relative humidity. | a variety of respirator filters and surgical masks were challenged with three aerosolized bacteria: mycobacterium abscessus (m.a.) (a rod), staphylococcus epidermidis (s.e.) (a sphere), and bacillus subtilis (b.s.) (a rod). tests were conducted at two flow rates (45 and 85 l./min) and two humidity levels (30 and 70%). aerosols were measured with a total-particle, direct-reading, spectrometer and a viable particle cascade impactor. measurements up- and downstream of the filter or mask were used i ... | 1997 | 9375526 |
| randomly amplified polymorphic dna pcr for comparison of mycobacterium abscessus strains from nosocomial outbreaks. | mycobacterium abscessus is an important cause of water-related nosocomial outbreaks or pseudo-outbreaks. strain comparison has relied on pulsed-field gel electrophoresis (pfge). unfortunately, almost 50% of strains cannot be assessed by this method. we studied 118 strains of m. abscessus previously studied by pfge by randomly amplified polymorphic dna (rapd) pcr, including isolates from eight nosocomial outbreaks. ten random primers were evaluated by using dna prepared by boiling or phenol-chlor ... | 1997 | 9399508 |
| a stationary-phase stress-response sigma factor from mycobacterium tuberculosis. | alternative rna polymerase sigma factors are a common means of coordinating gene regulation in bacteria. using pcr amplification with degenerate primers, we identified and cloned a sigma factor gene, sigf, from mycobacterium tuberculosis. the deduced protein encoded by sigf shows significant similarity to sigf sporulation sigma factors from streptomyces coelicolor and bacillus subtilis and to sigb, a stress-response sigma factor, from b. subtilis. southern blot surveys with a sigf-specific probe ... | 1996 | 8610119 |
| iatrogenic outbreak of m. chelonae skin abscesses. | we describe an outbreak of skin lesions due to mycobacterium chelonae subsp. abscessus associated with injections of lidocaine (lignocaine) given by a 'bioenergetic' (a practitioner of alternative medicine) in colombia. the lidocaine carpules and the lesions of the patients yielded mycobacteria with identical biochemical characteristics. using the methodology of sartwell and a case control design we examined the incubation period and assessed risk factors. of 667 potentially exposed individuals, ... | 1996 | 8760958 |
| infection with mycobacterium abscessus associated with intramuscular injection of adrenal cortex extract--colorado and wyoming, 1995-1996. | during march-april 1996, a physician in the denver area administered intramuscular injections of a preparation labeled "adrenal cortex injection" to 69 patients in colorado as part of a weight-loss regimen. as of august 7, a total of 47 (68%) of these persons were reported to have developed abscesses (diameters ranging from 0.5 cm to 4.0 cm) at the site of injection (either gluteal or deltoid muscle). an investigation of these episodes by the physician and the colorado department of public healt ... | 1996 | 8769652 |
| genetic basis for clarithromycin resistance among isolates of mycobacterium chelonae and mycobacterium abscessus. | resistance to clarithromycin among isolates of mycobacterium chelonae and m. abscessus was observed in 18 of 800 (2.3%) patients tested between 1990 and 1995. patients whose isolates were resistant had either disseminated disease or chronic lung disease, and the resistant isolates were recovered after clarithromycin monotherapy. sequencing of the gene coding for the 23s rrna peptidyltransferase region revealed a point mutation involving adenine at position 2058 (38%) or adenine at position 2059 ... | 1996 | 8807061 |
| from the centers for disease control and prevention. infection with mycobacterium abscessus associated with intramuscular injection of adrenal cortex extract--colorado and wyoming, 1995-1996. | 1996 | 8827955 | |
| activities of the glycylcyclines n,n-dimethylglycylamido-minocycline and n,n-dimethylglycylamido-6-demethyl-6-deoxytetracycline against nocardia spp. and tetracycline-resistant isolates of rapidly growing mycobacteria. | susceptibilities to the new semisynthetic tetracycline (tet) compounds n,n-dimethylglycylamido-minocycline (dmg-mino) and n,n-dimethylglycylamido-6-demethyl-6-deoxytetracycline (dmg-dmdot) were compared with those to doxycycline, minocycline, and tet for 198 tet-resistant (tetr) and 33 tet-susceptible (tets) clinical isolates of rapidly growing mycobacteria (rgm) including the mycobacterium fortuitum group, mycobacterium abscessus, mycobacterium chelonae, and mycobacterium mucogenicum and 68 iso ... | 1996 | 8849243 |
| successful treatment of chronic mycobacterium abscessus otitis media with clarithromycin. | 1996 | 8866816 | |
| mycobacterium abscessus osteomyelitis following a plantar puncture wound. | 1996 | 8879805 | |
| idiopathic disseminated bacillus calmette-guérin infection: a french national retrospective study. | disseminated bacillus calmette-guérin (bcg) infection after inoculation of live vaccine is considered to result from impaired immunity of the child. however, in half of the cases, regarded as idiopathic, no well-defined immunodeficiency condition can account for the infection. the objective of the present study is to report the prevalence, clinical features, associated infections, and outcomes of children with idiopathic disseminated bcg infection. | 1996 | 8885960 |
| [two cases of pulmonary disease caused by mycobacterium chelonae subsp. abscessus]. | we encountered two-cases of pulmonary disease caused by m. chelonae subsp. abscessus, [case 1] a 72-year-old man was admitted to the hospital because of fever. he had been observed for one year after being given a diagnosis of pulmonary disease caused by myocobacterium avium complex. sputum examination revealed acid-fast bacilli (gaffky 9). he recovered after administration of clarithromycin (cam) and other drugs. [case 2] a 61-year-old man was admitted to the hospital because of coughing and sp ... | 1996 | 8976085 |
| atypical mycobacterial infection of the orbit. | to describe the clinical presentation and successful management of an orbital infection caused by mycobacterium abscessus, a formerly unrecognized cause of orbital disease after penetrating trauma. | 1995 | 9097803 |
| mycobacterium abscessus infection of a norplant contraceptive implant site. | the authors report a case of mycobacterium abscessus infection of a subdermal levonogestrel implant (norplant) site. the infection lasted 12 weeks and was indolent, skin manifestations were low grade and difficult to detect. culture of exudate samples showed that m. abscessus was the only causative agent. after the implant was removed the patient's arm healed uneventfully without antimycobacterial therapy. the authors recommend that if gram staining of apparently infected material from an implan ... | 1995 | 7497391 |
| successful treatment of mycobacterium abscessus infections with multidrug regimens containing clarithromycin. | 1995 | 7620048 | |
| cutaneous infection with mycobacterium abscessus. | cutaneous infection with rapidly growing mycobacteria is uncommon and diagnosis may be difficult. however, the histopathological features are distinctive and may aid diagnosis. the three pathogenic species, mycobacterium fortuitum, m. chelonae and m. abscessus, show major differences in their antimicrobial sensitivities, and species identification is therefore important. we describe a case of infection with m. abscessus, and discuss the clinical and pathological features of such infections, and ... | 1995 | 7772489 |
| the role of mycobacteria other than tuberculosis (mott) in patients with cystic fibrosis. | the purpose of this study was to estimate the frequency of and evaluate the clinical impact of pulmonary mycobacterial infections among cystic fibrosis (cf) patients. 185 cf patients aged 2.2-38.5 years were screened by sputum samples and by intracutaneous skin tests against tuberculin and sensitins produced from mycobacterium chelonae subsp. abscessus, m. avium, m. intracellulare and m. scrofulaceum (the mais complex). the skin tests towards the sensitins in bcg-vaccinated patients (n = 60) wer ... | 1994 | 7855554 |
| structures of the glycopeptidolipid antigens of mycobacterium abscessus and mycobacterium chelonae and possible chemical basis of the serological cross-reactions in the mycobacterium fortuitum complex. | mycobacterium abscessus and mycobacterium chelonae, two members of the mycobacterium fortuitum complex, contain five major glycolipids. a combination of nmr spectroscopy, fast atom bombardment mass spectrometry and chemical degradation was used to elucidate their structures. all the compounds belong to the family of glycopeptidolipids. a 6-deoxy-alpha-l-talosyl unit, which may bear one or two acetyl groups, invariably occupies the site of glycosylation on the threonine residue in the various com ... | 1994 | 8025677 |
| mycobacterium abscessus pseudoinfection traced to an automated endoscope washer: utility of epidemiologic and laboratory investigation. | after 15 patients had positive cultures for mycobacterium abscessus without evidence of infection (i.e., pseudoinfection) following endoscopy, retrospective cohort studies of patients undergoing endoscopy and microbiologic sampling of the environment were done to examine potential nosocomial transmission and to identify the source and risk factors for m. abscessus pseudoinfection. in the epidemic period, m. abscessus-positive cultures were significantly more likely to be obtained during bronchos ... | 1994 | 8169416 |
| [two cases of lung infection due to mycobacterium chelonae subsp. abscessus]. | two cases of lung infection due to mycobacterium chelonae subsp. abscessus are reported. case 1, a 50-year-old female, was a secondary infection-type, and case 2, a 53-year-old female, was a primary infection-type. the 16 cases reported, between the ages of 29 and 76 years, there were 6 males and 10 females. the roentgenographic examinations, revealed that the ratio of the primary and secondary infection-type was 3:1. effective agents for this organism has not been yet confirmed. in the present ... | 1994 | 8176285 |
| recent changes in taxonomy and disease manifestations of the rapidly growing mycobacteria. | rapidly growing mycobacteria are a complex group of environmental organisms that cause human disease. eight taxonomic groups of pathogens are recognized of which three, the mycobacterium chelonae-like organism (mclo) and the two mycobacterium fortuitum third biovariant groups, have yet to receive names pending dna-dna homology studies. clinical disease due to all eight taxons usually consists of skin or soft tissue infections following trauma. nosocomial disease has become increasingly important ... | 1994 | 7698122 |
| chronic otitis media after tympanostomy tube placement caused by mycobacterium abscessus: a new clinical entity? | infections with nontuberculous mycobacteria (ntm) are being identified with increasing frequency, but the otologic manifestations of ntm infection are not well defined. mycobacterium abscessus is a ubiquitous rapidly growing mycobacterium (rgm) known to cause disease by inoculation after trauma. though reported following open heart and breast augmentation surgery, it is not recognized as a cause of sporadic post-tympanostomy tube otorrhea. this report presents detailed clinical information on si ... | 1994 | 8579134 |
| dna large restriction fragment patterns of sporadic and epidemic nosocomial strains of mycobacterium chelonae and mycobacterium abscessus. | large restriction fragment (lrf) pattern analysis of genomic dna using pulsed-field gel electrophoresis was performed on three reference strains, 32 sporadic isolates, and 92 nosocomial isolates from 12 epidemics of mycobacterium chelonae and mycobacterium abscessus. only 17 of 30 (57%) unrelated strains of m. abscessus, compared with 10 of 11 (91%) of m. chelonae strains, gave satisfactory dna extractions, with the remainder resulting in highly fragmented dna. drai, asni, xbai, and spei gave sa ... | 1993 | 8253968 |
| clinical significance, biochemical features, and susceptibility patterns of sporadic isolates of the mycobacterium chelonae-like organism. | mycobacterium chelonae-like organisms are nonpigmented rapidly growing mycobacteria whose clinical significance is unknown. we evaluated 87 sporadic isolates encountered in a clinical laboratory. most isolates (62%) were respiratory; only 2 of 54 (4%) (both from patients with aids) were clinically significant. among 33 nonrespiratory isolates, 20 of 33 (or 61%) were clinically significant. clinical diseases included posttraumatic wound infections and catheter-related sepsis. routine biochemical ... | 1993 | 8308116 |
| [rapid genetic identification system of mycobacteria]. | rapid colorimetric hybridization method was applied for the identification of mycobacteria and phylogenetic detection and identification system of mycobacteria of polymerase chain reaction method was designed. quantitative dna-dna hybridization in microdilution plate was used to identify 22 mycobacterial species. this method could identify 90% (178 among 194 trials) of clinical isolates within 3 hr. ten percent of clinical isolates did not belong to any of the established 22 species. through thi ... | 1992 | 1294787 |
| proposal of mycobacterium peregrinum sp. nov., nom. rev., and elevation of mycobacterium chelonae subsp. abscessus (kubica et al.) to species status: mycobacterium abscessus comb. nov. | we studied the taxonomic positions of the rapidly growing organism mycobacterium fortuitum and phenotypically related organisms. we confirmed that "mycobacterium peregrinum" atcc 14467t (t = type strain) is genetically independent of m. fortuitum atcc 6841t by using various dna hybridization conditions. strains that were genetically identified as "m. peregrinum" were phenotypically differentiated from m. fortuitum atcc 6841t. thus, we propose that "m. peregrinum" should be revived as an independ ... | 1992 | 1581184 |
| [contamination of endoscopes and endoscope washers by atypical mycobacteria]. | contamination of endoscopes and endoscope washers by atypical mycobacteria was studied. large amounts of atypical mycobacteria were detected with high frequency inside endoscopes and endoscope washers. the species of atypical mycobacteria was mycobacterium chelonae subsp. abscessus. antibacterial-effects of glutaraldehyde against isolated atypical mycobacteria were checked. sufficient antibacterial-effect was not obtained by 2% glutaraldehyde solution for endoscope sterilization. however, after ... | 1992 | 1624823 |
| occurrence and experimental infection of toads (bufo marinus and b. granulosus) with mycobacterium chelonei subsp. abscessus. | in a survey of 234 amazonian toads and frogs, six strains of mycobacterium chelonei subsp. abscessus were isolated from the liver or spleen of four of 66 bufo marinus (6.1%) and from the kidney or peritoneal fluid of two of 86 b. granulosus (2.3%). there were no histopathological lesions in the viscera of the infected animals. experimental infection of 29 captive b. marinus and b. granulosus, by the intraperitoneal route, with a pooled inoculum of m. chelonei subsp. abscessus caused five deaths ... | 1984 | 6438324 |
| radiometric detection of mycobacteria in routine blood cultures. | mycobacterium chelonei subsp. abscessus was detected radiometrically in routine blood cultures. the organism was detected in two patients without the use of special mycobacteriological media. | 1980 | 7012184 |
| mycobacterium abscessus (m. chelonei) infection of the knee joint: report of two cases following intra-articular injection of corticosteroids. | in 2 patients (3 knees) acute infectious arthritis of the knee developed following intra-articular injection of corticosteroids. the pathogenic organism responsible for the infection was found to be mycobacterium abscessus (m. chelonei). diagnostic difficulties were encountered due to the rarity of such infections and elusive identification of the organism with routine laboratory procedures. therapeutic approaches necessitated combined radical surgical procedures together with antituberculosis d ... | 1979 | 477069 |
| mycobacterium chelonei iatrogenic infections. | we report on two outbreaks of mycobacterium chelonei subsp. abscessus cutaneous infections, which occurred between june 1974 and april 1975 in a series of 24 patients (15 studied bacteriologically) subjected to venous stripping for varicose veins. the source of infection was the aqueous solution of merbromin used in presurgical care. | 1978 | 77278 |
| [injection abscesses caused by mycobacterium abscessus]. | 1972 | 4669854 | |
| mycobacterium abscessus infection in a puncture wound. | 1972 | 5049661 | |
| differentiation between mycobacterium abscessus and mycobacterium borstelense. | 1970 | 4244292 | |
| mycobacterium abscessus infection in an owl monkey (aotus trivirgatua). | 1970 | 4999881 | |
| comparative studies on the taxonomic relationship between mycobacterium abscessus and mycobacterium borstelense. incidence of mycobacterium abscessus in monkeys. | 1969 | 4986722 | |
| comparison of the pathogenicity for mice of mycobacterium fortuitum and mycobacterium abscessus. | the pathogenicity for mice of 12 strains of mycobacterium abscessus was compared with that for 8 strains of m. fortuitum. both species caused lesions in kidneys and produced "spinning disease" resulting from inner ear infections. no major differences in pathogenicity of these two species were demonstrated. strain to strain variation was marked, especially with m. abscessus. for example, 1.6 x 10(6) organisms of strain 11188 of m. abscessus produced death in four of five animals within 42 days, w ... | 1969 | 5370281 |
| [atypical acid fast bacilli, group iv rapid growers, with special reference to differentiation of mycobacterium fortuitum from mycobacterium abscessus]. | 1969 | 5389309 | |
| outbreak of injection abscesses due to mycobacterium abscessus. | 1969 | 5797954 | |
| an unusual acid-fast infection of the knee with subcutaneous, abscess-like lesions of the gluteal region; report of a case with a study of the organism, mycobacterium abscessus, n. sp. | 1953 | 13035193 |