Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| frequency of human toxocariasis in jos, plateau state, nigeria. | the enzyme-linked immunosorbent assay (elisa) was used to examine sera of 104 children and adults in jos, plateau state, nigeria for anti-toxocaral antibodies, out of which 31 (29.8%) were reactive. the seropositive rates were 30.4% for adults, 29.6% for children, 34% for females and 25.9% for males. however, the differences were not significant by age and sex. a highly significant association (p < 0.001) was observed between seropositivity and geography but none between seropositivity and dog o ... | 2000 | 10733730 |
| henoch-schönlein purpura associated with toxocara canis infection. | 2000 | 10743833 | |
| development of a highly specific recombinant toxocara canis second-stage larva excretory-secretory antigen for immunodiagnosis of human toxocariasis. | the specificity of the recombinant toxocara canis antigen developed for the immunodiagnosis of human toxocariasis was compared with that of the excretory-secretory antigen from t. canis second-stage larvae (tes) by enzyme-linked immunosorbent assay. a total of 153 human serum samples from patients infected with 20 different helminths, including 11 cases of toxocariasis, were examined. no false-negative reactions were observed for the toxocariasis cases. when the tes was used at concentrations of ... | 2000 | 10747116 |
| [ocular toxocariasis in 16-year old boy: a case report]. | the authors present a case of 16-year old boy with unilateral neurochorioretinitis induced by toxocariasis. quick diagnosis and effective treatment allowed to obtain clinical improvement. | 2000 | 10878960 |
| [clinical course of isolated larval infestation of orbit in children]. | clinical course of an isolated infestation of orbital tissues by larvae of helminths parasitizing in dogs (toxocara canis) has been followed up in 5 patients aged 6-13 years. the process ran a wave-like course for 3-8 months and was characterized by cyclic inflammatory changes in the orbit, presenting by toxic allergic tenonitis, regional lymphadenitis, optic nerve perineuritis with formation of parasitic granuloma detected by computer-aided rhoentgenotomography of the orbit. no clinical or labo ... | 2000 | 10918851 |
| quantitative comparison of various methods for detecting eggs of toxocara canis in samples of sand. | six techniques for recovering unembryonated toxocara canis eggs from sand samples were tested for efficiency and suitability for routine use. the tests were done under standardised conditions on 50g of sand samples contaminated experimentally with 10, 100 and 500 eggs of t. canis. best result was achieved by the method of dunsmore et al. [dunsmore, j.d., thompson, r.c.a., bates, i.a., 1984. vet. parasitol. 16, 303-311]. the results were expressed as the number of t. canis eggs recorded and perce ... | 2000 | 10936547 |
| efficacy of selamectin against experimentally induced and naturally acquired ascarid (toxocara canis and toxascaris leonina) infections in dogs. | the efficacy of selamectin against adult ascarids was evaluated in eight controlled and masked studies in dogs. three laboratory studies evaluated selamectin against experimentally induced infections of toxocara canis; three laboratory studies evaluated selamectin against naturally acquired infections of t. canis; one laboratory study evaluated selamectin against naturally acquired infections of both t. canis and toxascaris leonina; one field study evaluated selamectin against naturally acquired ... | 2000 | 10940533 |
| efficacy of selamectin administered topically to pregnant and lactating female dogs in the treatment and prevention of adult roundworm (toxocara canis) infections and flea (ctenocephalides felis felis) infestations in the dams and their pups. | the efficacy of selamectin in the treatment and prevention of naturally acquired toxocara canis infections and experimentally induced flea (ctenocephalides felis felis) infestations in dams and their suckling pups was evaluated by administering selamectin to the adult females only, approximately 40 and 10 days before parturition and 10 and 40 days after parturition. unit doses of the commercial formulation of selamectin were administered to the dams to provide at least the minimum recommended do ... | 2000 | 10940534 |
| a family of secreted mucins from the parasitic nematode toxocara canis bears diverse mucin domains but shares similar flanking six-cysteine repeat motifs. | infective larvae of the parasitic nematode toxocara canis secrete a family of mucin-like glycoproteins, which are implicated in parasite immune evasion. analysis of t. canis expressed sequence tags identified a family of four mrnas encoding distinct apomucins (tc-muc-1-4), one of which had been previously identified in the tes-120 family of glycoproteins secreted by this parasite. the protein products of all four cdnas contain signal peptides, a repetitive serine/threonine-rich tract, and varyin ... | 2000 | 10950959 |
| immunofluorescent localization of intermediate filaments (ifs) in helminths using anti-mammalian ifs monoclonal antibody. | intermediate filaments (ifs) make up the cytoskeleton of most eukaryotic cells. in vertebrates, a number of if proteins have been identified, showing distributions unique to tissue or cell type. information on helminth ifs is limited to some nematode species. to observe immunofluorescent localization of ifs in helminth tissues, we selected a murine hybridoma clone producing igm antibody to multiple types of mammalian if proteins and examined cross-reactivity to helminth proteins. the selected mo ... | 2000 | 10958445 |
| [zoonotic parasitosis transmitted by dogs in the chaco salteño, argentina]. | toxocara canis and ancylostoma spp. are geohelmints that parasites dogs and can eventually affect humans, mainly children, causing visceral and cutaneous larva migrans respectively, constituting a serious public health problem. this study was carried out in two towns located in the xerophilous forest chaco salteño where humans live closely with many animals, including dogs. hematological values and anti-toxocara canis antibodies, determined by elisa in serum, were evaluated in 98 children from t ... | 2000 | 10962811 |
| a parasitological survey of wild red foxes (vulpes vulpes) from the province of guadalajara, spain. | an epizootiological survey of leishmaniosis, coccidiosis and parasitic helminths in 67 foxes (vulpes vulpes) was conducted in guadalajara (central spain). examination for parasitic protozoa revealed prevalences of 74% leishmania (determined by molecular methods) and 2.9% coccidia oocysts (fecal flotation). survey of parasitic helminths (fecal flotation/necropsy) demonstrated the presence of nine species, including six nematodes, two cestodes and one trematode. nematodes were the most common para ... | 2000 | 10996735 |
| differentiation of toxocara canis and t. cati eggs by light and scanning electron microscopy. | in this study, we investigated the morphological identification of toxocara canis and t. cati eggs on the basis of light and scanning electron microscopic (sem) observations. t. canis and t. cati eggs used in this study were recovered from the uteri of respective gravid female worms. measurement of egg size was not helpful in the differentiation of these species, because approximately 90% of eggs measured were of similar size. using sem, we were able to differentiate t. canis eggs from t. cati e ... | 2000 | 10996740 |
| tropical pyomyositis and human toxocariasis: a clinical and experimental study. | 2000 | 11020398 | |
| biological activity of paecilomyces genus against toxocara canis eggs. | saprophytic soil fungi can exert ovicidal and ovistatic effects on helminths with differing degrees of efficiency. the representatives of such fungi from temperate regions, paecilomyces lilacinus (thom) samson and p. marquandii (masse) hughes, exhibit recognized ovicidal activity on some nematodes. we evaluated the action in vitro of p. lilacinus and p. marquandii on the zoonotic canine roundworm eggs of toxocara canis. eggs exposed and unexposed to fungal samples were observed by both light and ... | 2000 | 11068820 |
| skin manifestations associated with toxocariasis: a case-control study. | human toxocariasis is one of the most common zoonotic helminthiases. the recent development of sensitive and specific diagnostic laboratory tests has led to identify a large spectrum of diseases, including cutaneous diseases, induced by toxocara infection. objective: the purpose of our study was to assess the risk of having a positive toxocara elisa test in patients with different cutaneous symptoms. | 2000 | 11096194 |
| seroprevalence of toxocariasis in blood donors of gualeguaychú, argentina. | 2000 | 11127236 | |
| comparison of the sensitive screening kit with two elisa sets for detection of anti-toxocara antibodies. | three serological tests (elisa novum, elisa pu and toxocarachek) were compared using excretory-secretory (es) antigen of second stage larvae of toxocara canis on two sets of sera from patients aged 1-15 years, living in town and in the country, suspected of having larval toxocarosis. of 60 serum samples examined for the presence of anti-toxocara igm and igg antibodies 35 (58.3%) were positive with elisa novum, 30 (50.0%) with elisa pu and 37 (61.6%) with toxocarachek. a significantly higher sero ... | 2000 | 11127346 |
| ocular larva migrans caused by toxocara cati in mongolian gerbils and a comparison of ophthalmologic findings with those produced by t. canis. | to elucidate the pathogenic potential of toxocara cari, we observed the ophthalmologic changes of the fundi in mongolian gerbils, meriones unguiculatus, after oral inoculation of 17 embryonated eggs/g body weight. ophthalmic conditions in 8 t. cati-infected gerbils were monitored using an ophthalmoscope from day 0 to day 156 and were compared with those of 57 t. canis-infected gerbils. the results showed that t. cati larvae migrated into the eye of the gerbil and then elicited ophthalmic changes ... | 2000 | 11128493 |
| shared epitope for monoclonal ir162 between anisakis simplex larvae and clonorchis sinensis and cross-reactivity between antigens. | ir162 is a rat monoclonal ige antibody (mab). in the investigation of rat ige production, the antigens recognized by ir162 (ir-ags) were found to be expressed by a variety of helminthic parasites. by western blot analysis, ir162 detected bands in crude extracts of anisakis simplex larvae, clonorchis sinensis, paragonimus westermani, plerocercoids of spirometra mansoni, and toxocara canis. excretory-secretory material from a. simplex larvae also contained a protein recognized by ir162. ir162 mab ... | 2000 | 11128497 |
| identification of a new c-type lectin, tes-70, secreted by infective larvae of toxocara canis, which binds to host ligands. | infective larvae of the dog roundworm toxocara canis survive in the tissues of their hosts for extended periods in a state of developmental arrest, successfully evading immune destruction. this survival strategy is thought to be mediated by t. canis excretory/secretory (tes) products which downregulate or divert the immune response. we purified one of the major tes products, tes-70 and gained amino acid sequence from 4 tryptic peptides. these peptides were matched to a predicted protein from a c ... | 2000 | 11128806 |
| eosinophilic pleocytosis and myelitis related to toxocara canis infection. | toxocara canis causes the visceral larva migrans syndrome in which central nervous involvement is rare. we report the case of a 40-year-old woman presenting with a subacute weakness of the right leg and dysaesthesiae in the right th8-th10 dermatomas. spinal magnetic resonance imaging examination showed abnormal hyperintensity within the spinal cord. cerebrospinal fluid analysis revealed eosinophilic pleocytosis. antibody titres to toxocara canis were higher in the cerebrospinal fluid than in the ... | 2000 | 11136359 |
| improved methods for recovering eggs of toxocara canis from soil. | the ingestion of soil in parks and public places containing eggs of toxocara may constitute a significant health risk, particularly to children. to determine the most efficient method for extracting eggs from experimentally contaminated soil, two consecutive studies were undertaken. four techniques, including washing, sieving, vacuum, and the one recommended by the world health organization, were evaluated. recovery rates of over 85% were recorded with both washing and sieving methods. using the ... | 2000 | 11138025 |
| five cases of ocular toxocariasis confirmed by serology. | we report 5 cases of ocular toxocariasis in korean adults complaining of visual impairment along with floating or bubbling sensation. fundoscopic examination revealed a retinal detachment along with exudate in 4 cases. they all showed typical reaction by elisa and immunoblot against toxocra excretory-secretory antigen. one case showed high level of anti-toxocara ige antibodies (34,000 toxocara units/l) as well as increased level of serum total ige antibodies and the specific ige antibodies for 3 ... | 2000 | 11138321 |
| [ocular toxocariasis. value of local immunodiagnosis]. | toxocara canis is a nematode that may be involved in human ocular toxocariasis. specific immunotesting is of importance but may be negative as toxocara antigens may localize exclusively in vitreous humor. we report here the case of one patient with optic disc toxocariasis granuloma negative for toxocara canis immunodiagnostic on serum. clinical diagnosis was confirmed by toxocara canis specific enzyme-linked immunosorbent assay (elisa) on aqueous humor showing elevated titers of antibodies. syst ... | 2000 | 11139695 |
| [toxocara and bronchial hyperreactivity--results of a seroprevalence study]. | for more than 30 years the ascarid toxocara canis, a parasite of the dog, has been considered a possible cause of allergic-pulmonal irritations (i.e. asthma bronchial) in man. according to a british study thousands of people are presumably suffering from asthma bronchial as a consequence of toxocara infestations. the aim of our recent study was the assessment of the toxocara seroprevalence in patients of varying bronchial reactivity and status of atopy suffering from respiratory disturbances. 19 ... | 2000 | 11144007 |
| [environmental contamination with toxocara sp. eggs in public squares and parks from santiago, chile, 1999]. | most of cases of visceral larva migrans syndrome are caused by toxocara canis larvae. man acquires the infection by accidental ingestion of ripe eggs of the helminth. in order to find out the frequency of the presence of toxocara sp. eggs in dog fecal specimens from public places of santiago city in 1999 july-september a study was carried out in 84 squares and 12 parks from 32 counties. three fecal samples were collected in each of these places, making a total of 288. each sample was processed a ... | 2000 | 11338980 |
| choroidal neovascular membrane: a late complication of inactive toxocara chorioretinitis. | 2000 | 10783962 | |
| effect of ivermectin on the brown dog tick, rhipicephalus sanguineus. | ivermectin (ivomec) proved to be effective in controlling r. sanguineus. all brown dog ticks infesting the treated dogs (subcutaneous injections) with 1.5 ml or 2 ml/50 kg dropped off within 4 or 3 days respectively. the dropped off ticks were completely inactive and died within one day or two. ticks exposed to filter papers impregnated with 100 micrograms/ml (66.67%) died within four days. a dose of 1.5-2 microliters/50 kg eradicated toxocara canis infection in four dogs, and caused shrinkage o ... | 2000 | 10786024 |
| human toxocarosis. its seroprevalence in the city of la plata. | toxocara canis is very common in dogs throughout the world. it is the primary cause of visceral larva migrans (vlm) in humans. soil contaminated with t. canis embryonated eggs is the main source of infection of man. our objective was to describe toxocara seroprevalence in humans in the city of la plata associated with some determinants such asage, presence or absence of clinical manifestations and risk factors. blood samples were collected at random from 156 patients of different sex and age, wi ... | 2000 | 10800184 |
| the new subfamily of cathepsin-z-like protease genes includes tc-cpz-1, a cysteine protease gene expressed in toxocara canis adults and infective stage larvae. | 2000 | 10831387 | |
| [exposure to toxocariasis and tularemia among workers at białowieza national park]. | everyday contact of the workers of białowieza sanctuary with animals may create a risk of infection by microorganisms attacking animals. the reported study was undertaken for carrying out an epidemiological analysis of tularemia and toxocarosis in this group of workers. tularaemia infection was not found in then. in 12% of these workers antibodies to toxocara canis were found, and fire workers had articular borreliosis. antibodies to taxocara were disclosed in 10% of the białowieza population no ... | 2000 | 11349600 |
| toxocara canis: determination of the origin of antigenic materials released from infective larvae. | indirect fluorescent antibody test (ifat) revealed antigenic focal areas in the brain tissues of mice infected by toxocara canis as determined by the light, electron and fluorescent microscopic examination of the infective larvae. the oesophageal gland was well defined and its secretory activity was evident. the oral orifice and the lumen of oesophagus were strongly fluorescing by using anti es serum. these indicate the antigenic property of oesophageal gland secretion. intestine appeared to be ... | 2000 | 11198365 |
| prevalence of toxocara canis infection in dogs in the warszawa area. | the evaluation of toxocara canis infection in stray dogs from two shelters and private owners dogs in the warszawa district was the aim of this study. in 1998 five hundred faecal samples were examined. the homeless dogs were found more infected than those kept as pets. t. canis was recorded in 3.4% and 8.8% of stray dogs from the shelters and in 0.4% of animals from flats. the higher prevalence of infection in homeless dogs was due to high density of dogs population, worse environmental conditio ... | 2000 | 16886327 |
| [the risk factors of toxocara canis infestation in population of patients from the lublin region]. | the risk factors of toxocara canis infestation were assessed among population of patients from the lublin region. sera from 151 patients suspected of toxocarosis were tested on the presence of the specific antibodies by elisa (biokema-bordier, switzerland). sera from 74 women and 77 men were collected (mean: 24 years; range: 0-74 years). women sera were found positive in 27 cases (36.5%) and men in 34 cases (44.2%). positive results were found in the following age groups: young people up to 15 y ... | 2000 | 16886328 |
| [relationships between the prevalence of toxocara eggs in dogs' faeces and soil]. | toxocariasis is a cosmopolitan infection of dogs and cats. humans (mainly children) become infected by accidentally ingesting embryonated eggs from the environment. the studies were conducted on the role of dogs in the epidemiology of human toxocariasis. a total of 112 soil samples and 110 fecal samples were collected from the same public places in poznań, including backyards in the centre of the city, playgrounds and public squares grounds. of these soil samples, 6.3 % were positive for toxocar ... | 2000 | 16886343 |
| [own clinical observations of toxocara infections]. | toxocarosis clinical forms wers diagnosed according to kraus et. al. (1995). there were three forms: 1) asymptomatic - marked by hypereosynophilia and elisa positive serologic reaction, 2) minor - with cutaneous, pulmomary and pseudorheumatic lesions, 3) major - with hepatosplenomegaly and multifocal inflammatory lesions of organ of sight. over the years of 1994-1997 in infectious, parasitic and tropical diseases clinic of the voivodship specialist hospital of lódź we found and treated 137 toxoc ... | 1999 | 16886380 |
| helminth parasites of dogs from two resource-limited communities in south africa. | biological samples were collected from dogs in resource-limited communities in the north-west and gauteng provinces of south africa to assess the prevalence of helminth parasitism. these samples included adhesive tape peri-anal skin swabs and fresh faecal samples for helminth examination, and thick and thin blood films (smears) and whole-blood samples in anticoagulant for examination of filarial nematode microfilariae and haemoprotozoa. the eggs of ancylostoma caninum, toxocara canis, toxascaris ... | 1999 | 10855829 |
| [prevalence of toxocara spp in public playgrounds in a town of central italy] | in this study, the prevalence of toxocara spp. was evaluated in the soil of 22 public playgrounds of ancona (italy). the public playgrounds were selected according to the different areal distribution (centre, low-lying areas centre, hilly areas suburbs) within the urban area of ancona, central italy. in six playgrounds there were signs restricting access for dogs; all of them were frequented by children. parasites were found in the soil samples from 21 out of 22 playgrounds (95.5%). the most pre ... | 1999 | 12736552 |
| [lung manifestation of visceral larva migration syndrome due to toxocara canis infection]. | 32 year-old patient was hospitalized because of disseminated lung lesions. 2 years earlier he manifested chorioditis. exact disease history suggested suspicion of toxocare infection. the diagnosis was confirmed by serological tests with anti-toxocara canis antibodies, bronchial lavage and chest ct scan. administration of 450 mg of dietylokarbamasin (hetrazan) resulted in complete resolution of pulmonary lesions. | 1999 | 11057106 |
| a case of presumed ocular toxocariasis in a 28-year old woman. | this is a case of presumed ocular toxocariasis in a 28-year old woman complaining of a sudden onset of nasal side field defect of the right eye. the patient had been suffering from uveitis for ten months. fundoscopic examination of the right eye showed a rhegmatogenous retinal detachment. furthermore, a retinochoroidal granulomatous lesion was observed nearby the tear site. scleral buckling, cryotherapy, and gas injection(sf6, pure gas, 0.7 cc) were conducted. mebendazole was prescribed for one ... | 1999 | 10761408 |
| [the role of the water factor in the dissemination of toxocara eggs and the spread of toxocariasis in a megalopolis]. | the water factor in transfer of the activators toxocariasis was not taken into account by parasitologists earlier. yet in the urbanized ecosystems (first of all--in the megalopolis) it can have rather appreciable importance in distribution of toxocariasis in animals and man. our researches which have been carried out in reservoirs of moscow with the "wild" and the "organized" beaches, have revealed various, but as a whole their significant, of contaminations by invasion eggs toxocara (toxocara c ... | 1999 | 10771766 |
| nephrotic syndrome associated with toxocara canis infection. | this case report describes nephrotic syndrome in a 7-year-old boy coincident with toxocara canis infection. this rare association was confirmed by elevated toxocara-specific igm titres. treatment with corticosteroids resulted in remission of renal symptoms as well as abatement of the t. canis infection. the relationship between t. canis infection and glomerular disease is still unclear; nephrotic syndrome may be another manifestation of t. canis infection. | 1999 | 10715718 |
| diffuse bilateral subacute neuroretinitis: first patient with documented nematodes in both eyes. | to describe the first patient with documented evidence of diffuse unilateral subacute neuroretinitis (dusn) in both eyes. | 1999 | 10532442 |
| parasitological survey on wild carnivora in north-western tohoku, japan. | in the winter of 1997-1998, we collected parasitological data from 60 wild carnivora in the north-western part of tohoku region, japan. these included 7 foxes (vulpes vulpes japonica), 20 raccoon dogs (nyctereutes procyonoides viverrinus), 29 martens (martes melampus melampus), 3 weasels (two mustela sibirica itatsi and one m. nivalis namiyei), and one japanese badger (meles meles anakuma). roundworms (toxocara canis in foxes and toxocara tanuki in raccoon dogs), hookworms (ancylostoma kusimaens ... | 1999 | 10535507 |
| prevalence of intestinal helminths of dogs and foxes from jordan. | necropsy of 340 stray and semi-stray dogs (canis familiaris) and nine red foxes (vulpes vulpes) from jordan revealed that 239 dogs (70.3%) and all foxes were infected with at least one intestinal helminth species. no trematodes were found in the intestine of these hosts. the overall infection rates with cestodes, nematodes and acanthocephalans in dogs were 66.8%, 4.4% and 2.9%, respectively. the following cestodes were identified: echinococcus granulosus (9.4%), taenia pisiformis (11.8%), t. hyd ... | 1999 | 10540955 |
| fever, cough, and nodules on ankles. | 1999 | 10584725 | |
| immunomodulative effect of muramyldipeptide in mice with larval toxocarosis. | the phagocytic ability of polymorphonuclear leukocytes, the metabolic activity of peritoneal macrophages, the proliferative response of t- and b-cells, and the production of specific anti-toxocara antibodies were studied in paratenic hosts with experimental larval toxocarosis after treatment with the immunomodulator muramyldipeptide for 119 days. peroral infection of mice with 2,500 toxocara canis eggs partially reduced the numbers of cells and inhibited the activity of all cellular immune-respo ... | 1999 | 10599929 |
| characterization of antigenic property of toxocara canis and toxascaris leonina adults and larvae through immunodiagnostic electrophoresis (sds-page) and western blot technique. | differential molecular studies were performed by sodium dodecyle sulphate polyacrylamide gel electrophoresis--sds-page--between somatic antigen of toxocara canis and toxascaris leonina, adults and larvae, recovered from dogs. sds-page of both adults somatic antigen showed two closely similar bands (90.00, 91.95 kda and 69.25-70.56 kda). each parasite had characteristic bands clustered in different molecular weights. while for their larval antigen, t. canis showed a very different antigenic profi ... | 1999 | 10605487 |
| interleukin-5 transgenic mice show enhanced resistance to primary infections with nippostrongylus brasiliensis but not primary infections with toxocara canis. | in this study, interleukin-5 (il-5) transgenic mice with lifelong eosinophilia were assessed for resistance to primary infections with two tissue-invading nematodes, nippostrongylus brasiliensis and toxocara canis. relative to nontransgenic littermates, three lines of il-5 transgenic mice with varying degrees of eosinophilia all displayed enhanced resistance to n. brasiliensis. although the timing of final worm expulsion was similar in transgenic and nontransgenic hosts, intestinal worms in tran ... | 1999 | 9916122 |
| henoch-schönlein purpura associated with toxocara canis infection. | we describe a case of henoch-schönlein purpura in the onset of toxocara canis infection. the diagnosis was made in a 17-year-old boy based on the association of palpable purpura, oligoarthritis, acute abdominal pain, microhematuria, and cutaneous vasculitis. toxocariasis, suggested by hypereosinophilia and domestic contact with a puppy, was confirmed by anti-toxocara igg and ige and western blot. complete spontaneous resolution occurred within a few days. transient presence of antinuclear antibo ... | 1999 | 9972983 |
| cytologic findings in vitreous fluids. analysis of 74 specimens. | to review the cytologic findings of vitreous specimens and propose a simplified approach to them. | 1999 | 10097710 |
| visceral larva migrans and pyogenic liver abscess. | 1999 | 10201506 | |
| [a case of visceral larva migrans due to toxocara canis mimicking intrahepatic cholangiocarcinoma]. | 1999 | 10214079 | |
| aetiological study of the presumed ocular histoplasmosis syndrome in the netherlands. | to investigate whether presumed ocular histoplasmosis syndrome in the netherlands is caused by histoplasma capsulatum and whether other risk factors might play a role in the pathogenesis of this syndrome. | 1999 | 10216050 |
| [an attempt to extract an intraretinal nematode located in the papillomacular bundle]. | the nematode infection of the retina is a rare disease with sight threatening prognosis. untreated eyes usually become blind. there are different types of clinical progression: granuloma causing tractional detachment chronic inflammation called diffuse unilateral subacute neuroretinitis (dusn) and rapid loss of vision named "ocular wipe-out syndrome". efficient drugs are not available. the progression of the disease can be stopped by killing the nematode by means of photocoagulation. for parasit ... | 1999 | 10218207 |
| detection of circulating antigens and antibodies in toxocara canis infection among children in chengdu, china. | in order to determine the seroprevalence of toxocara spp. infection in children from chengdu, we performed an enzyme-linked immunosorbent assay (elisa) and sandwich elisa (s-elisa) with excretory-secretory antigens isolated from second-stage larvae of toxocara canis (tes-ag elisa). the seroprevalences of t. canis antibodies in the children from rural areas, urban districts, and urban districts with recent ascaris lumbricoides infection were 17.7% (59/333), 2.1% (4/186), and 2.6% (1/38), respecti ... | 1999 | 10219304 |
| cloning and expression of an aquaporin-like gene from a parasitic nematode. | 1999 | 10340494 | |
| ultrasound findings in children with toxocariasis: report on 18 cases. | to evaluate abdominal ultrasound (us) findings in children infected with toxocara canis. | 1999 | 10382204 |
| efficacy of fenbendazole granules and pyrantel pamoate suspension against toxocara canis in greyhounds housed in contaminated runs. | the efficacy of fenbendazole granules against toxocara canis in naturally infected greyhounds housed in contaminated environments was evaluated. eight pens, each containing three to seven greyhounds, 3-12 months of age, were randomly allotted into two treatment groups. greyhounds in group 1 were treated with fenbendazole granules mixed in their feed at 50 mg/kg/day for 3 consecutive days once a month for 4 months. greyhounds in group 2 were treated with pyrantel pamoate suspension at 5.0 mg/kg p ... | 1999 | 10384907 |
| a method for isolation and purification of nematode larvae. | a new apparatus for isolating, purifying, and collecting larvae of nematodes is described. results of collecting larvae with baermann's traditional method and the pasteur pipette cotton plug method are compared to those obtained with the device in this research note. it is simple, easy to use, and a more effective apparatus for the isolation, purification, and collection of nematode larvae. | 1999 | 10386459 |
| [the behavior of angiotensin-converting enzyme in patients with uveitis]. | serum angiotensin-converting enzyme (ace) is considered as a marker in many disorders, especially in sarcoidosis. the aim of this study was to assess ace activity using haiakari spectrophotometry in patients with non-sarcoidosis uveitis before and after treatment. material and methods: 36 patients, including 21 adults and 15 children, were investigated. ace concentration was increased mostly in patients with recurrent toxoplasmic and toxocaral iridocyclitis and choroiditis. results: it was demon ... | 1999 | 10401207 |
| new animal model for human ocular toxocariasis: ophthalmoscopic observation. | although human ocular toxocariasis causes severe vision defect, little is known about its aetiology, diagnosis, and treatment. to develop a new animal model for human ocular toxocariasis, ophthalmological findings of fundi in mongolian gerbils, meriones unguiculatus, and balb/c mice were investigated following infection with toxocara canis. | 1999 | 10413704 |
| toxocariasis: serological diagnosis by indirect antibody competition elisa. | toxocariasis is caused by infection of man by toxocara canis and toxocara cati larvae, the common roundworm of dogs and cats. because larvae are difficult to detect in tissues, diagnosis is mostly based on serology. non specific reactions are observed mainly due to cross-reactivity with ascaris sp antigens. this investigation aimed at developing and evaluating an indirect antibody competition elisa (iace) employing a specific rabbit igg anti-toxocara canis excretory-secretory antigens as the com ... | 1999 | 10413956 |
| visceral larva migrans: migratory pattern of toxocara canis in pigs. | the migratory pattern of toxocara canis was investigated following infection of pigs with 60000 infective eggs. groups of six pigs were slaughtered at 7, 14 and 28 days after infection (p.i.), and the number of larvae in selected organs and muscles was determined by digestion. a group of uninfected pigs was used as negative controls for blood parameters and weight gain. toxocara canis migrated well in the pig, although the relative numbers of larvae recovered decreased significantly during the e ... | 1999 | 10428632 |
| transmission trials, its2-pcr and rapd-pcr show identity of toxocara canis isolates from red fox and dog. | toxocara canis isolates from dog and from red fox were compared in transmission trials and with molecular analysis using rapd-pcr technique and comparison of the its2 sequence. after oral infection of bitches with 20,000 embryonated t. canis eggs of vulpine and canine origin, the vertical transmission to pup's was examined. all animals of both groups developed typical clinical symptoms of toxocarosis. the haematological, serological, parasitological and post mortem results showed no differences ... | 1999 | 10435795 |
| [toxocariasis caused by toxocara canis: clinico-epidemiological aspects]. | 1999 | 10439541 | |
| [asthma and covert toxocariasis]. | the relationship between asthma and covert toxocariasis was studied in 38 patients with asthma and 44 control individuals (without asthma). inclusion/exclusion criteria were determined. an elisa test based on the detection of anti-toxocara canis (e/s antigen) serum immunoglobulin g (ig g) and e (ig e) was determined in both groups. ordinary allergens and e/s antigen of t. canis injections were used to evaluate cutaneous reactivity. the seroprevalence in patients with asthma was 68.42%, and in th ... | 1999 | 10451562 |
| identification of abundantly expressed novel and conserved genes from the infective larval stage of toxocara canis by an expressed sequence tag strategy. | larvae of toxocara canis, a nematode parasite of dogs, infect humans, causing visceral and ocular larva migrans. in noncanid hosts, larvae neither grow nor differentiate but endure in a state of arrested development. reasoning that parasite protein production is orientated to immune evasion, we undertook a random sequencing project from a larval cdna library to characterize the most highly expressed transcripts. in all, 266 clones were sequenced, most from both 3' and 5' ends, and similarity sea ... | 1999 | 10456930 |
| ocular toxocariasis: a rare presentation of a posterior pole granuloma with an associated choroidal neovascular membrane. | ocular toxocariasis is a rare infection caused by the nematode larvae of toxocara canis, which is commonly found in dogs. human transmission is usually via geophagia, the ingestion of food contaminated with the toxocara eggs, or contact with infected puppies, often resulting in devastating ocular and/or systemic effects. distribution is worldwide; however, a higher incidence is demonstrated in the united states. | 1999 | 10457701 |
| a novel c-type lectin secreted by a tissue-dwelling parasitic nematode. | many parasitic nematodes live for surprisingly long periods in the tissues of their hosts, implying sophisticated mechanisms for evading the host immune system. the nematode toxocara canis survives for years in mammalian tissues, and when cultivated in vitro, secretes antigens such as tes-32. from the peptide sequence, we cloned tes-32 cdna, which encodes a 219 amino-acid protein that has a domain characteristic of host calcium-dependent (c-type) lectins, a family of proteins associated with imm ... | 1999 | 10469567 |
| hepatic imaging studies on patients with visceral larva migrans due to probable ascaris suum infection. | visceral larva migrans (vlm) is a disease usually observed in children in which the larvae of animal parasites invade and reside in human tissues for long periods. although the common causal species of vlm are toxocara canis and t. cati, we identified three adult patients with vlm, probably due to ascaris suum, whose diagnosis was made by specific immunoserological tests. the patients complained of respiratory symptoms, and laboratory tests showed pronounced eosinophilia, but neither larvae nor ... | 1999 | 10475929 |
| [55-year old patient with fatigue, ascites, recurrent diarrhea and eosinophilia]. | 1999 | 10476486 | |
| visceral larva migrans syndrome complicated by liver abscess. | we describe a case of visceral larva migrans syndrome complicated by liver abscess, pericardial effusion and ascites. to our knowledge, these findings have not been reported previously. the structural and immunological alterations caused by visceral larva migrans are thought to lead to the development of visceral abscesses. | 1999 | 10482069 |
| strategic use of ivermectin during pregnancy to control toxocara canis in greyhound puppies. | twenty-one greyhound bitches were bred (day 0) and housed throughout their pregnancies on three greyhound breeding farms in kansas. these dogs were assigned randomly to one of four treatment groups. group a dogs (6) were given ivermectin subcutaneously (300 microg/kg) on day 0 (the first day the dogs were bred), and days 30 and 60 of gestation. group b dogs (6) were given ivermectin (300 microg/kg sq) on day 42. group c dogs (3) were given ivermectin (300 microg/kg sq) on days 0, 30, and 60 plus ... | 1999 | 10488732 |
| anthelmintic efficacy of tinidazole against the progression of toxocara canis larvae to the brain in mice. | the anthelmintic effect of tinidazole (100 mg/kg per day for 3 successive days) was tested in male swiss cf-1 mice infected with second-stage toxocara canis larvae at challenge doses of 250, 500, 1000, and 1500 embryonated eggs per mouse. the drug was given orally on days 3-5 postinfection (p.i.) to one-half of the animals, and all mice were killed on day 40 p.i. the number of larvae recovered from each mouse's brain and skeletal muscle was then scored in both groups. tinidazole yielded a highly ... | 1999 | 10494809 |
| [the association between human toxocariasis and pyogenic abscesses]. | the association between hepatic abscesses and schistosomiasis mansoni was confirmed by clinical and experimental studies. other parasites may cause systemic immunologic changes and local structural alterations in the affected organs that can facilitate the seeding of these areas by bacteria. tropical pyomyositis, pyogenic liver and renal abscesses are frequent diseases in tropical areas. the visceral larva migrans syndrome is caused by the presence, in the human body, of larvae of worms that hav ... | 1999 | 10495673 |
| cloning and characterisation of a prohibitin gene from infective larvae of the parasitic nematode toxocara canis. | infective larvae of the parasitic nematode toxocara canis express an mrna (tc-pro-1) encoding a predicted protein that shares significant homology with prohibitin, a protein involved in inhibition of cell proliferation - the closest homologues of tc-pro-1 include an expressed sequence tag (est) from caenorhabditis elegans and drosophila l2cc, a protein thought to be essential for larval development and moulting. other homologues include prohibitin from rat and human and an est from saccharomyces ... | 1998 | 10524759 |
| visceral larva migrans and tropical pyomyositis: a case report. | we report a case of tropical pyomyositis in a boy who presented with a severe febrile illness associated with diffuse erythema, and swelling in many areas of the body which revealed on operation extensive necrotic areas of various muscles that required repeated débridement. the patient gave a history of contact with dogs, and an elisa test for toxocara canis was positive. he also presented eosinophilia and high serum ige levels. staphylococcus aureus was the sole bacteria isolated from the muscl ... | 1998 | 10436659 |
| [toxocariasis in dogs and contamination of soil with toxocara spp. eggs in the poznań region]. | dogs and soil samples from poznań city and the nearby small town murowana goślina were surveyed for the presence toxocara eggs. on the areas examined, the range of dog's infections with t. canis and the contamination of the soil with the infective stage of toxocara spp. were not paralleled. in poznań city out of 617 dogs examined 11.8% were infected with adult form of t. canis and since 1980th the prevalence has decreased. in murowana goślina as much as 35.2% dogs out of 352 examined were infect ... | 1998 | 10321087 |
| skin problems and parasites in children: 2. parasitic worms. | the skin is an organ which has many important functions for body maintenance and health. infestation by a wide variety of worms is a worldwide public health problem. threadworms are believed to infect up to 50% of london school children. dogs and other pets have much to teach children but regular care of pets should include attention to hygiene. nurses and midwives can help to educate the public about worms and their advice can help prevent toxocara infections. | 1998 | 9814365 |
| inhibition of lymphoproliferative response and its restoration with a glucan immunomodulator in mice with experimental larval toxocarosis. | a high infective dose of taxocara canis eggs (2,500 eggs per mouse) induced a partial immunosuppression in mice, manifested by inhibition of the proliferative response of splenic t and b cells to polyclonal activators. a glucan immunomodulator given to infected animals at the beginning of the experiment showed a marked stimulative and restorative effect on the parasite-suppressed lymphoproliferative response. the ability of t. canis to migrate in the host was reduced in glucan-treated animals by ... | 1998 | 9821300 |
| effects of monoclonal antibodies to adhesion molecules on eosinophilic myocarditis in toxocara canis-infected cba/j mice. | eosinophilic myocarditis followed by fibrosis of the cardiac muscle was observed in addition to peripheral blood eosinophilia in cba/j mice infected with toxocara canis. the infected mice were used as an experimental model of eosinophilic endomyocarditis associated with hypereosinophilic syndrome. effects of in vivo treatment with moabs to adhesion molecules on eosinophilic myocarditis were examined using this experimental model. expressions of intercellular adhesion molecule-1 (icam-1) and vasc ... | 1998 | 9822282 |
| the role of icam-1/lfa-1 and vcam-1/vla-4 interactions on t helper 2 cytokine production by lung t cells of toxocara canis-infected mice. | in order to study the effect of costimulatory signals on t helper type 2 (th2) cytokine production, monoclonal antibodies (mab) against cell adhesion molecules (cam) were added to cells in culture obtained from the lungs of toxocara canis (tc)-infected mice followed by the determination of interleukin-5 (il-5) and il-4 in the supernatants of the culture. es-stimulated il-5 production in the supernatant of total lung cells was reduced by 25% when anti-intercellular adhesion molecule-1 (anti-icam- ... | 1998 | 9824506 |
| effect of "in vitro" cultivation time on the infectivity of toxocara canis eggs. | 1998 | 9830737 | |
| interleukin-5 modulates interleukin-8 secretion in eosinophilic inflammation. | serum and balf (bronchoalveolar lavage fluid) il-8 levels and serum levels were investigated in toxocara canis infected guinea-pigs and the role of il-5 as a modulator of cytokine secretion was studied. serum levels increased early in infected animals, exceeding control levels 4 h after infection, peaked between days 6 and 18, and continued to exceed control levels after 48 days of infection. serum and balf il-8 levels showed the same profile as blood eosinophilia, increasing 6 days post-infecti ... | 1998 | 9839698 |
| [meningoencephalitis caused by toxocara canis]. | 1998 | 9853051 | |
| toxocara cati-induced ocular toxocariasis. | 1998 | 9869809 | |
| löeffler endomyocarditis: a clinical presentation as right ventricular tumor. | a four-year-old girl presented with an apical mass of the right ventricle, pulmonary embolism and hypereosinophilia, and was shown to be infected with toxocara canis. cardiac involvement was represented by endomyocardial fibrosis, mainly at the apex of the right ventricle, mural thrombi and tricuspid regurgitation. hypereosinophilia appears to be the head point at the basis of multiple organ damage in löeffler endomyocarditis. the disease mechanism proposed is the eosinophilic production of pero ... | 1998 | 9870201 |
| prevalence of anti-toxocara antibodies in a random sample of inpatients at a children's hospital in vitória, espírito santo, brazil. | in the streets of vitória, in the state of espírito santo, brazil, are large number of stray dogs, many of which are infected with toxocara canis, suggesting a high risk for human infection. in order to investigate the prevalence of toxocara infection in children in espírito santo we studied the prevalence of anti-toxocara antibodies in 100 random inpatients over one year of age, at the children's hospital n.s. da glória, the reference children's hospital for the state. all the sera were collect ... | 1998 | 9876441 |
| production of eosinophil chemotactic factor by cd8+ t-cells in toxocara canis-infected mice. | production of eosinophil chemotactic factor by t-lymphocytes (ecf-l) was examined in toxocara canis-infected mice. when spleen cells from t. canis-infected mice were cultured in serum-free rpmi1640, ecf-l production was detectable in an antigen-specific manner. the ecf-l production peaked at day 9 post-infection and then decreased. depletion of thy 1.2+ cells or cd8+ cells completely abrogated ecf-l production, whereas depletion of cd4+ cells did not, indicating that cd8+ t-cells are involved in ... | 1998 | 9493213 |
| effect of ozone treatment on toxocara canis eggs. | the effect of ozone treatment on the development and viability of toxocara canis eggs was studied. despite treatment with ozone, unembryonated t. canis eggs could develop into viable second-stage larvae when assayed by larvae recovery after oral inoculation into mice. the viability of second stage larvae of t. canis was also not affected by ozone treatment. no significant difference was observed in the larvae recovery count and migratory pattern of the ozone-treated larvae and the untreated cont ... | 1998 | 9524939 |
| toxocara canis infection in the paratenic host: a study on the chemosusceptibility of the somatic larvae in mice. | a research on formulation and dosage strategies of anthelmintics have been conducted in mice experimentally infected with eggs of toxocara canis. multidose treatments commenced at days 2, 14, 81, 87 and 123 postinfection. results indicated no detectable difference in the chemosusceptibility of the migrating early infection larvae and the resting hypobiotic chronic infection larvae. application of medicated dry food (pellets) may be a simple way of improving efficacy of treatment compared to oral ... | 1998 | 9561710 |
| anthelmintic efficacy of oxibendazole against some important nematodes in dogs and cats. | the anthelmintic efficacy and safety of the oxibendazole component in a combination oxibendazole-niclosamide paste were investigated in dogs and cats and in litters of pups with naturally acquired nematode infections. a single dose of 15 mg oxibendazole/kg body weight given to 70 dogs and to 29 cats reduced faecal worm egg counts (epg) by 97.6% for toxocara canis, 95.7% for trichuris vulpis, 94.6% for ancylostoma caninum, and 100% for toxascaris leonina. in cats, 96.7% efficacy was demonstrated ... | 1998 | 9563164 |
| antistriational antibodies during toxocara canis, trichinella spiralis infections. | the parasitic infections (toxocara can is, trichinella spiralis) are characterized by general and local symptoms including fever, muscle pain and swelling. the question was asked whether the muscle changes that occur due to larva migrans give rise to the autoimmune response. the presence of antistriational antibodies (astrabs) was determined in the following groups of patients: group 1--66 patients with toxocariasis and the presence of anti-toxocara antibodies, group 2--22 patients suspected of ... | 1998 | 9611680 |
| [ocular toxocariasis in austria]. | two women (aged 21 and 44 years) were referred because of a suspect retinal lesion. an ophthalmological examination in both revealed prominent retinal granulomatous foci, probably ocular toxocariasis. both women were otherwise well; both reported close contact with dogs. | 1998 | 9627571 |
| detection of sequence variation in parasite ribosomal dna by electrophoresis in agarose gels supplemented with a dna-intercalating agent. | this study evaluated the use of a commercially available dna intercalating agent (resolver gold) in agarose gels for the direct detection of sequence variation in ribosomal dna (rdna). this agent binds preferentially to at sequence motifs in dna. regions of nuclear rdna, known to provide genetic markers for the identification of species of parasitic ascarid nematodes (order ascaridida), were amplified by polymerase chain reaction (pcr) and subjected to electrophoresis in standard agarose gels ve ... | 1998 | 9629896 |
| incidence of patent toxocara canis infection in bitches during the oestrous cycle. | the incidence of patent toxocara canis infection as result of reactivation of somatic larvae with subsequent tracheal migration was investigated by faecal examination during 23 oestrous cycles of 15 bitches. blood samples were collected for determination of total and differential leukocyte counts, prolactin concentration, and toxocara titre. five pregnant dogs were used as controls. in the cyclic dogs there were no alterations in white blood cell counts or prolactin concentration, in contrast wi ... | 1998 | 9684299 |
| an epidemiological survey of echinococcus granulosus and other helminths in animal populations in northern israel. | in a survey carried out during the period may 1995 to november 1996, in communities of various ethnic groups in northern israel, 206 dogs were examined for echinococcus granulosus and other intestinal helminth parasites by arecoline hydrobromide purges and the coproantigen-elisa. the arecoline test was performed close to the owners' homes, using plastic sheets secured to the ground. from 56 dogs examined in the muslim town of tamra, six (10.7%) were found to be infected with e. granulosus. four ... | 1998 | 9687593 |
| a novel method for the recovery of toxocara canis in mice. | acid-isolating and acid digestion techniques were used to recover the larvae of t. canis from the tissues of mice and the acid-isolating technique in particular proved to be an effective method. | 1998 | 9687601 |