Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
[exoenzymes of dermatophytes isolated from acute and chronic tinea].the presence of five enzymes (deoxyribonuclease, elastase, lipase, caseinase and hemolysin) in 76 strains of dermatophytes 47 of trichophyton rubrum, 10 of t. mentagrophytes, five of t. tonsurans, 10 of microsporum canis and four of epidermophyton floccosum) isolated from 30 cases of acute dermatophytosis and from 46 chronic ones was determined by a qualitative plate assay; in the same way, the presence of these five enzymes with the acute and chronic dermatophytosis was correlated. it was obser ...19947938939
itraconazole versus griseofulvin in the treatment of tinea capitis: a double-blind randomized study in children.tinea capitis is a fungal infection in which topical therapy is often unsuccessful. griseofulvin has been considered to be a first-line therapy. other antifungal agents are the azole derivatives. among these, itraconazole was compared with griseofulvin in children in a double-blind study.19948002149
antidermatophytic activity of allylamine derivatives.the allylamine derivatives are a new class of synthetic antifungal agents. the antidermatophytic activity of the two main compounds, naftifine and terbinafine were compared in vitro with those of ketoconazole and itraconazole by agar dilution. eighty eight clinical isolates of dematophytes comprising of microsporum canis (50), m. audouinii (5), trichophyton rubrum (6) t. mentagrophytes (5), t. violaceum (12), t. simii (5), t. verrucosum (1), t. soudanense (1), t. erinacie (1) and epidermophyton ...19947868170
[the occurrence of keratinolytic fungi in the polluted environment of the labedy district in gliwice].this study was undertaken to find relationships between the degree of bacteriological contamination with qualitative composition of potentially pathogenic keratinolytic fungal population in soil, sediment and air samples from the labedy district in gliwice (poland). the examined soil samples were characterized by the predominance of botryotrichum piluliferum, chrysosporium anamorph of arthroderma curreyi, myceliophthora anamorph of ctenomyces serratus, chrysosporium pannicola and trichphyton aje ...19947792523
microsporum canis infection in a 5-year-old boy: transmission from the interior of a second-hand car.microsporum canis is one of the most common zoophilic dermatophytes. if transmitted to humans, inflammatory lesions may develop, e.g. on the scalp. m. canis was isolated from a 5-year-old boy living in a suburban area who suffered from a long-standing, mildly inflammatory lesion on the scalp that had been treated for several months with anti-eczematous regimens. there had been no contact with animals, e.g. cats or dogs, in the previous months, but the lesions had developed a few weeks after the ...19947845421
polymerase chain reaction-based detection of dermatophyte dna with a fungus-specific primer system.there is significant clinical interest in primers which are specific for fungi and do not hybridize to dna of other eukaryotes or prokaryotes. such primers would allow specific amplification of fungal dna from human tissue samples containing fungi. fungal identification to the species level could follow by direct sequencing or restriction analysis. several previously described primer systems cross-react with dna of plants and animals. we have designed a primer system that amplifies a fragment of ...19947845424
ecology and epidemiology of dermatophyte infections.our knowledge of ecology and epidemiology of dermatophytes and the factors influencing their transmission has helped us understand better the natural history of dermatophytoses. it seems that the anthropophilic agents of scalp infection are being eradicated in developing nations. the exception is trichophyton tonsurans-related tinea capitis in north america. microsporum canis is a prevalent agent of tinea capitis in many regions of the world, and this could be related to close association of hum ...19948077503
enzyme patterns of dermatophytes.exoenzymes produced by common dermatophytes, in addition to their ability to cause cutaneous inflammation, are thought to contribute to fungal spread. to investigate the patterns of enzymes released by common dermatophytes as well as scopulariopsis brevicaulis, the fungi were grown in liquid media containing either hair, stratum corneum, neopeptone or lipids, or in rpmi medium. enzymes recovered from the culture supernatants were compared using the api-zyme test. as a result, the widest range of ...19947935585
dermatophytoses in iran.a total of 12,150 cases of suspected dermatophytoses in different areas of iran were studied between 1986 and 1991. the age groups most commonly infected were 1-9 and 20-29 years. clinical diagnosis was confirmed in only 9345 cases by laboratory examination. of these positive samples, 1633 cases were found to be positive by direct microscopic observation only, 429 by culture only and 7283 by both techniques. scalp ringworm of children was the most common type of tinea. but according to the rate ...19947935592
microsporum canis infection of the thumb-nail. 19948033403
human dermatophyte-responsive t-cell lines recognize cross-reactive antigens associated with mannose-rich glycoproteins.resistance to dermatophyte infections has been shown to be mediated in part by t lymphocytes. the dermatophyte antigens recognized by human t lymphocytes and their degree of cross-reactivity were analyzed. dermatophyte-responsive t-cell lines were generated by in vitro sensitization to crude fungal extracts obtained from trichophyton rubrum, trichophyton tonsurans, microsporum canis and epidermophyton floccosum. proliferation was measured by incorporation of 3h-thymidine. the human t-cell lines ...19947921653
immunogenicity in guinea-pigs of a crude ribosomal fraction from microsporum canis.the immunogenicity of a crude ribosomal fraction (crf) extracted from microsporum canis was tested by assessing protection of vaccinated guinea-pigs (gp) against a challenge with the dermatophyte. stimulation of the humoral as well as the cellular immune systems of these animals was evaluated by elisa and the lymphocyte stimulation tests, respectively. in addition, the immune response elicited by the m. canis crf was examined for cross-reactivity towards trichophyton verrucosum antigen. the dura ...19948147094
development of an experimental model of microsporum canis infection in cats.an experimental infection model was developed for reliable induction of microsporum canis skin infections in cats, using a defined number of macroconidia harvested from the fungus in culture. the strain of m. canis used produced highly fluorescent hairs under ultraviolet illumination. kittens 8 to 9 weeks of age (n = 6) received 10(5) macroconidia applied topically to a closely-shaved area of skin. sites were dressed with an occlusive bandage for 3 days, then grooming was restricted for an addit ...19949133054
epidemiological and diagnostic features of canine and feline dermatophytosis in the united kingdom from 1956 to 1991.between 1956 and 1991, 8349 samples from dogs and cats were received for investigation of suspected dermatophytosis, and 1368 (16 per cent) yielded positive cultures. cats had a significantly higher proportion of positive cultures (26 per cent) than dogs (10 per cent), and of these microsporum canis accounted for 92 per cent in cats and 65 per cent in dogs. the other isolates were diverse but mainly sylvatic dermatophytes, and m gypseum was isolated on only four occasions. different breeds of do ...19938212483
tinea capitis in trinidad.characteristics of clinically diagnosed cases of tinea capitis from trinidad are described. tinea capitis comprised 29.5% of all dermatophytoses seen at one general hospital out-patient dermatology clinic during a one-year period. males were more often affected than females and there was a predominance of patients of african descent. among the dermatophytes cultured trichophyton tonsurans was the most prevalent (52.9%), followed by microsporum canis (20.0%) and m. audouinii (18.6%). less frequen ...19938254711
immunohistological characterization of the cellular infiltrate in dermatophytosis.the local cell composition of skin infections caused by trichophyton rubrum (13 cases) and microsporum canis (2 cases) was examined using monoclonal antibodies and the abc immunoperoxidase technique. the number of langerhans cells increased both in the epithelium and in the dermis of the mycotic area. apart from these, only t cells were found in the dermis, among which helper cells were predominant. the helper/suppressor ratio showed variations depending upon the pathogen.19938264718
dermatophytosis of children in kuwait: a prospective survey.tinea capitis in children is widely reported, whereas there have been only isolated reports on involvement of sites other than the scalp. the purpose of this study was to examine the epidemiological features and treatment responses of dermatophytosis of children in kuwait.19938270336
[incidence of various etiologic agents of superficial mycosis].in a retrospective review of laboratory records at the department of mycology, national institute of microbiology "dr. carlos g. malbrán", during the period june 1989-july 1991, 1225 putatively immunocompetent cases of superficial mycoses were identified. ninety five percent of these patients were adults and 5% children. among the total cases, dermatomycoses were caused, 67.6% by dermatophytes, 25.9% by yeasts, 5.9% by malassezia furfur. and 0.5% by other fungi, as proven by the isolation of the ...19938140245
isolation and physico-chemical characterization of an antifungal and antibacterial peptide produced by bacillus licheniformis a12.an antifungal substance named peptide a12-c has been purified to homogeneity from supernatants of sporulated cultures of bacillus licheniformis a12. it consists of a 0.77-kda hydrophilic peptide containing two residues of glu and one of arg, ala, pro, tyr and orn. no fatty acids, phosphorus or carbohydrates have been detected. peptide a12-c is active on several fungi (microsporum canis cect 2797, mucor mucedo cect 2653, m. plumbeus (ccm f 443, sporothrix schenckii cect 2799 and trichophyton ment ...19937763922
microsporum canis infection in sheep. 19938488650
microsporum canis scalp ringworm: its primary or secondary ectothrix character.this study supports the view that, in cases of tinea capitis due to a microsporum canis infection, ectothrix arthroconidium formation is extrapilary and arises from intrapilary hyphae. the hyphae of m. canis perforate and digest the hair cuticle to alter its appearance from a normally identifiable structure of imbricated cells with a distal free border, to a grossly altered and pathological layer. conidium production mainly takes place outside the hair shaft and forms thick clusters between the ...19938108682
[uncommon caseous maxillary sinusitis of dental origin caused by microsporum canis].the authors report an uncommon case of maxillary sinusitis due to microsporum canis. to their knowledge this is the first observation in which a zoophilic dermatophytic fungus which grows usually on keratin has been isolated in a dental maxillary sinusitis in human. this observation makes it possible to discuss nosologic and diagnostic features of dental caseous sinusitis and fungal sinusitis which are often or too often called aspergillosis sinusitis.19938210096
increasing importance of trichophyton tonsurans in childhood tinea in new south wales. the pattern of childhood tinea in new south wales, australia 1979-1988: the emergence of trichophyton tonsurans as an important pathogen in tinea capitis in white children.a retrospective study was undertaken of 192 cases of culture proven tinea capitis occurring between 1979 and 1988 in a predominantly white population of children in new south wales (nsw). the aim of the study was to identify whether trichophyton tonsurans was increasing in importance in the causation of this condition in australia as it was in many other parts of the world. the results of our study were compared with those of earlier australian studies. our study demonstrated that trichophyton t ...19938240189
[evaluation of susceptibility of dermatophytes to antifungal drugs].a serial dilution and a disc method were used for evaluation of susceptibility of 50 dermatophyte strains belonging to the species trichophyton rubrum, trichophyton mentagrophytes, microsporum canis and epidermophyton floccosum. following drugs were investigated: griseofulvin, pimaricin, clotrimoxazole, miconazole, ketoconazole, biphonazole and naftifin. application of two methods of testing resulted in high convergence of determinations. naftifin was most effective and pimaricin least active. a ...19938309309
the ringworm riddle: an outbreak of microsporum canis in the nursery.tinea capitis, the most common fungal infection in children, is rare in neonates. we report six patients in a level ii intermediate care nursery who developed nosocomial dermatophyte infections caused by microsporum canis. the investigation, which led to the identification of a nurse as the common source, is described. the nurse had an indolent infection with m. canis. human to human transmission is exceedingly rare for m. canis. the literature regarding neonatal dermatophyte infections is discu ...19938426773
humoral immune responses in cats with dermatophytosis.the igg and igm classes of antibodies to a water-soluble antigen preparation derived from microsporum canis were determined by elisa in the sera of 79 cats with dermatophytosis confirmed by results of fungal culture, and of 46 specific-pathogen-free-derived, barrier-maintained cats with no previous exposure to dermatophytes. of the 79 cats with dermatophytosis, the species isolated were: m canis from 72, m gypseum from 6, and trichophyton mentagrophytes from 1. concentrations of soluble m canis ...19938291765
[reported frequency of dermatophytes in cats and dogs in austria].during four years (1988-1991) 384 skin scrapings and hair samples obtained from cats and 636 samples obtained from dogs in austria were examined routinely for dermatophytes. in cats dermatophytes were isolated or found positive in unstained koh preparation in 50.3% of the samples. 90.7% of these cats were proved to be infected with microsporum canis. trichophyton mentagrophytes was isolated in 5.2% and trichophyton spp. in 2.1% of the positive samples. in dogs dermatophytes were isolated from 12 ...19938306866
in vitro susceptibility of dermatophytes to antifungal drugs: a comparison of two methods.there is an evidence that some fungal strains are resistant to certain antimycotic drugs with resulting therapeutic failures. unlike testing of antibacterial agents, the activity of these drugs against the given fungal strains is not tested routinely. the paper presented is an approach to such a procedure.19938340195
[identification of dermatophytes as possible agents in clinically and microbiologically diagnosed dermatophytosis].in this study we have investigated the distribution of dermatophyte species clinically and microbiologically on 110 patients with dermatophytosis. the distribution of the dermatophytes according to the localization sites are: tinea capitis 13 (11.8%), t. corporis 12 (10.9%), t. inguinalis 22 (20%), t. pedis et manum 47 (42.7%), t. unguinum 16 (14.5%). the species of dermatophytes which have been cultured were, trichophyton rubrum 32 (29%), t. mentagrophytes 32 (29%), t. schoenleini 4 (3.6%), t. ...19938361407
[gum-like exudate from laguncularia racemosa (white mangrove) as culture media for fungi].morphological studies of eight species of fungus: aspergillus flavus microsporum canis, epidermophyton floccosum, curvularia lunata, cladosporium carrionii, natrassia mangífera (edo. scytalidium), sporotrix schenckii y rhizophus oligosporus, which belong to families mucedinaceae, dematiaceae and mucoraceae have been carried out in support medium based in gum exudate from laguncularia racemosa (mangle blanco). this native polimer contains galactose, arabinose, rhamnose, uronic acid and proteins. ...19938123711
tinea corporis bullosa.the paper reports a case of tinea corporis bullosa in a 63-year-old woman. near the classical annular lesions on the anterior surface of the left leg, the patient presented frank bullous lesions. serous fluid from the bulla yielded microsporum canis, the first report of the association of this fungus with bullous lesions in tinea corporis. the patient was investigated with routine examinations and immunological studies which showed an intense inflammatory process much greater than in usual cases ...19938366877
oral itraconazole versus topical bifonazole treatment in experimental dermatophytosis.guinea pigs, infected with either trichophyton mentagrophytes or microsporum canis, were treated orally or topically with azole antifungals daily for two weeks. fungi located in the stratum corneum were affected similarly by both treatment schedules, showing typical cell wall changes after azole exposure and necrosis of internal organelles. fungi located in the hair sheaths were affected only by the oral treatment, which not only prevented invasion of the inner hair structures and inflammatory r ...19938396203
epidemiology of the dermatophytoses in the florence area of italy: 1985-1990. trichophyton mentagrophytes, epidermophyton floccosum and microsporum gypseum infections.between 1985 and 1990 we observed 2085 cases of dermatophytoses in the florence area of italy. trichophyton rubrum and microsporum canis were the major etiological agents. 126 cases of dermatophytoses observed during this period were caused by trichophyton mentagrophytes. most of the patients came from rural areas or they kept pets. epidermophyton floccosum ranked fourth in frequency (95 cases). the patients were adults and mainly males, most of whom engaged in sports or lived in group environme ...19938413498
tinea capitis in saudi arabia.tinea capitis is a dermatophyte infection of the scalp, eyebrows, and eyelashes caused by species of microsporum and trichophyton. the purpose of this study was to discover the incidence and causal agents of tinea capitis in saudi arabia.19938425800
ultrastructure of trichophyton violaceum.the ultrastructure of different fungi have been described in recent literature; however, few reports have concerned dermatophytes.19938440569
humoral and cellular immune responses to microsporum canis in naturally occurring feline dermatophytosis.peripheral blood lymphocytes isolated from cattery cats which were culture positive for microsporum canis, or from cats which had recovered from m. canis infection, showed a significantly greater mean in vitro blastogenic response to m. canis antigen than lymphocytes from uninfected cats. mean lymphocyte reactivity to concanavalin a was higher in cats which had recovered from infection than in either culture positive or uninfected cats, whereas reactivity to phytohemagglutinin was highest in the ...19938509949
purification, characterization, and lytic activity against naegleria fowleri of two amoebicins produced by bacillus licheniformis a12.bacillus licheniformis a12 produces two amoebolytic substances (amoebicins a12-a and a12-b) in liquid media during sporulation. both substances have been purified and characterized. they are heat- and protease-resistant peptides containing aspartic acid, glutamic acid, serine, proline, and tyrosine in a molar ratio of 5:2:2:2:2. no fatty acids or carbohydrates have been detected. their molecular weight is 1,430. purified amoebicins a12-a and a12-b exhibit amoebolytic action against naegleria fow ...19938517742
dermatophytes and dermatophytoses in the milan area between 1970 and 1989.between 1970 and 1989 we examined 13,019 patients with dermatophytoses in the milan area, northern italy. the results obtained during the 1980-89 period were compared with those obtained in the years 1970-79. from the data collected, tinea corporis emerged as the most frequently observed dermatophytosis, followed by tinea pedis and unguium. as far as dermatophytes are concerned, the dermatological pattern is dominated by microsporum canis and trichophyton rubrum. other species, such as epidermop ...19938015563
biotypes of the dermatophyte microsporum distortum.during a study of the epidemiology of microsporum canis and closely related species, sub-specific variation was demonstrated within thirteen isolates of microsporum distortum based on the pattern of carbohydrate utilization. strains from three continents could be differentiated by their utilization of trehalose and erythritol. isolates from new zealand yielded the same patterns as m. canis (arthroderma otae (-)); examination of 120 isolates indicated that m. canis could not be biotyped by carboh ...19921474986
low voltage scanning electron microscopy study of naftifine activity on microsporum canis.scanning electron microscopy (sem) is at present considered a good way to observe the morphological alterations induced by an antifungal on pathogenic fungi. owing to its high precision, low voltage scanning electron microscopy (lvsem) improves the quality of observations. the microsporum canis morphology alterations induced by naftifine at a concentration of 0.9 microgram ml-1 (10 times the minimum inhibitory concentration (mic) for 7 days were studied in lvsem. the young lateral ramifications ...19921302809
inhibition of growth of dermatophytes by indian hair oils.a survey on the use of hair oils for hair dressings by the indian population revealed that mustard oil is preferred by males and coconut oil by females. amla oil is used equally by both. these oils contain different percentages of various saturated and unsaturated fatty acids which largely determine their toxicity against dermatophytes. for microsporum canis, m. gypseum and trichophyton rubrum, amla oil was most toxic, followed by cantharidine and coconut oil, while trichophyton mentagrophytes w ...19921302812
pattern of dermatophyte infection in singapore.dermatophyte infection is the fourth commonest skin disorder seen in the national skin centre in singapore. a prospective study was carried out from june 1990 to march 1991 to determine the epidemiology and pattern of dermatophyte infections seen in this centre. two hundred patients who had a clinical diagnosis of dermatophyte infection and confirmed by direct microscopy were included into the study. cultures for dermatophyte were done on sabouraud's dextrose agar with chloramphenicol and cycloh ...19921295417
structure modification and biological activity of some griseofulvin derivatives.griseofulvin is an orally acting anti-fungal antibiotic with very limited water solubility. five chemical modifications were made on the griseofulvin structure in order to evaluate these changes on the antifungal and water solubility properties. antifungal activity was measured against tricophyton mentagrophytes, t. rubrum, t. terrestre, and microsporum canis. the oxime of griseofulvin was the most potent of the five compounds tested, but it was only of equal or less potency than griseofulvin. t ...19921296044
mycological findings in feline immunodeficiency virus-infected cats.thirty-five fiv-seropositive cats and 55 fiv-seronegative matched cats were examined for yeasts (oropharyngeal swabs) and dermatophytes (hair brushings). the frequency of isolation of candida albicans and cryptococcus neoformans was significantly higher in the former group. the only dermatophyte isolated was microsporum canis. its prevalence was three times higher among fiv-infected cats than among control animals.19921325555
incidence of dermatophytoses in rabbit farms in catalonia, spain, and its repercussion on human health.over the past decades there has been an important increase in the incidence of dermatophytoses in humans as a result of contact with animals, although etiological agents can vary as can the animals transmitting the disease. a large-scale study was carried out in 220 farms raising rabbits for consumption. most of the farms (85%) were located in the autonomous community of catalonia (spain). mycological studies showed that 79.5% of the rabbits were infected with trichophyton mentagrophytes var. gr ...19921397196
morphological and biochemical variability of microsporum canis strains.seventy-two strains of microsporum canis, of different origins, were examined from a morphological point of view and tested in relation to their hydrolytic activity on tyrosine, xanthine, casein, gelatin, their ureasic activity and their capacity to assimilate different nitrogenous substances. the morphological aspects, that vary within the m. canis isolates, were constant in the strains isolated from rabbits. a strain with particular features was isolated many times from the dogs and cats comin ...19921397197
in vitro susceptibility to antimycotics of microsporum canis isolates from cats.one hundred thirty-four isolates of microsporum canis, obtained from cats, were tested for in vitro susceptibility to various antifungal agents. the fungi were classified as susceptible, resistant, and intermediate by measuring the size of the zone of inhibited growth on yeast nitrogen base agar medium. clotrimazole had the highest activity (99.2%), followed by tioconazole (89.6%), griseofulvin (88.8%), econazole (73.1%), ketoconazole (50.7%), miconazole (15.7%), and isoconazole (12.7%). we foun ...19921429182
superficial mycoses in saudi arabia.between june 1988 and december 1990, 1018 cases of superficial mycoses were investigated. diagnosis was confirmed by microscopic examination in 503 cases and the causal agent was isolated in 490 cases. tinea capitis accounted for 47.7% (92.5% in children below 10 years of age). the frequency of other clinical types in descending order was pityriasis versicolor 25.8%, tinea corporis 9%, onychomycosis 5.8%, tinea pedis 4%, intertrigo 3.9% and tinea cruris 2.8%. erythrasma was encountered three tim ...19921445094
outbreak of tinea capitis by trichophyton tonsurans and microsporum canis in niterói, rj, brazil.18 girls from an orphanage (orfanato santo antônio) in niterói presented tinea capitis due to trichophyton tonsurans (15 cases-83.3%) and microsporum canis (3 cases-26.7%). comments are made about clinical, mycological and therapeutic aspects of this microepidemic.19921342076
preliminary report on the isolation of a dysgonic variety of microsporum canis together with the normal variety from a cattery.the isolation of a dysgonic variety of microsporum canis from a large number of cats and kittens in a cattery is described. the normal variety of this fungus was isolated at the same time from the same animals. dysgonic varieties are thought to be mutants of normal strains, but this isolation of both forms together suggests that the relationship may be more complex.19921480210
extensive dermatophytoses caused by trichophyton mentagrophytes and microsporum canis in a patient with aids.retrospective studies have shown the occurrence of episodes of deep or superficial fungal infections in 58 to 81% of hiv/aids patients as a result of impairment of cell immunity. we describe a case of disseminated cutaneous dermatophytoses caused by trichophyton mentagrophytes and microsporum canis in a patients with aids. diagnostic and therapeutic problems in relation to this unusual presentation are emphasized as well as the importance of an early mycologic diagnosis to prescribe antifungal t ...19921494359
is microsporum canis infection about to become a serious dermatological problem?in europe, especially in the mediterranean, the incidence of microsporum canis infection has been on a steep increase during the recent years. in some countries (italy) and geographic areas (slovenia), m. canis is the most often isolated dermatophyte. in slovenia (yugoslavia), a dramatic increase in the incidence of m. canis infection has been observed recently, both in absolute figures and as compared to the rest of isolated dermatophytes. m. canis is a cause of tinea most prevalent in children ...19921498385
[shifts in the species spectrum of mycoses in the netherlands from 1970-1990].a review is presented of yeast and mould infections occurring in humans in the netherlands. the occurrence of the dermatophytes trichophyton rubrum and t. mentagrophytes tends to increase, while microsporum canis and particularly epidermophyton floccosum have become less common. the yeast candida glabrata is particularly often involved in infections of the urinary tract. candida krusei, c. parapsilosis and c. tropicalis have become less significant. remarkable differences are found between the s ...19921557162
dermatophytosis of children in kuwait.five hundred fifty-six children constituted 39.5% of total smear- and culture-positive cases of dermatophytosis and 0.6% of the total new dermatology outpatients seen over a period of five years. males outnumbered females. the youngest child was a 20-day-old neonate (age range 20 days-12 yrs) with a peak of fungal infections seen in patients between 4 and 6 years of age. microsporum canis was the most prevalent (70.5%) species, followed by trichophyton violaceum, microsporum audouinii, trichophy ...19921574472
tinea capitis caused by microsporum canis in a newborn. 19921587671
[in vitro antifungal activity of itraconazole, a new triazole antifungal agent, against clinical isolates from patients with dermatomycoses].in vitro antifungal activities of itraconazole (itz), a triazole antifungal agent, against clinical isolates obtained from patients with superficial and subcutaneous mycoses were examined using the agar dilution method on casitone agar. the clinical isolates tested were 7 species and 263 isolates including trichophyton mentagrophytes (104 isolates), trichophyton rubrum (103 isolates), microsporum canis (3 isolates), epidermophyton floccosum (2 isolates), candida albicans (32 isolates), malassezi ...19911652655
dermatophytoses in cusco (peru).a total of 90 cases of suspected dermatophytoses was observed over a period of 9 months in the city of cusco (peru) and in its environs. the age groups most commonly infected were 1-10 and 11-20 year old. the most common tineae diagnosed were tinea capitis (13.3%) and tinea unguium (11.1%). only four species of dermatophytes were isolated: microsporum canis (52.4%), trichophyton mentagrophytes (35.7%), tr. rubrum (9.5%) and epidermophyton floccosum (2.4%). dry weather, low temperature and high a ...19911749399
dermatophytosis in children and adolescents: epidemiological, clinical, and microbiological aspects changing with age.during a four year period, a total of 84 cases of dermatophytosis were seen in patients from 0 to 17 years of age attending our out-patient department. the sex distribution was about equal in preadolescents. males predominated among adolescents. a peak incidence at early school age was due to cases of tinea capitis, mainly caused by microsporum canis. a peak among adolescents was due to cases of tinea pedis, mainly caused by trichophyton rubrum. in general, patients with trichophyton rubrum infe ...19911761791
polyacrylamide gel electrophoresis patterns of some microsporum species.the paper reports observations made of various microsporum species during a page pattern study of the epidemiology of microsporum canis. it is shown that m. audouinii can readily be distinguished from m. canis but that m. equinum is more difficult to separate. m. rivalierii was distinguishable from m. audouinii, confirming previous reports. m. distortum could not be separated from m. canis by page gels of total protein or by isozyme patterns generated. there are particular problems with studies ...19911803231
fungal infection as a cause of skin disease in the eastern province of saudi arabia: tinea corporis and tinea cruris.in the period between april 1984 and april 1988 a total of 4,294 clinically suspected cases of dermatomycoses were examined for causative fungi. of these cases 768 (17.9%) were suspected as tinea corporis (427 cases) and tinea cruris (341 cases). twenty two different nationalities were represented. both sexes were involved and the age range was 19 days to 70 years. of the 768 patients examined, 738 (96.1%) had their diagnosis confirmed by direct microscopy and in 631 of these positive cases the ...19911820522
an atypical microsporum canis isolate.an atypical strain of microsporum canis isolated from a two-year-old boy with tinea corporis is described. when cultured on lactritmel agar the strain presented the typical pigment of m. canis without developing characteristic macroconidia. after 6 weeks, scarce, rudimentary, fusiform macroconidia 120-150 microns long developed on lactritmel and sablac microcultures. in vitro, the strain developed hair perforating organs. experimental inoculation of a healthy volunteer produced a tinea with typi ...19911824421
nonscalp hair infection caused by microsporum canis in patient with acquired immunodeficiency syndrome. 19911869658
endemic microsporum canis infection in a sheep flock. 19912043092
plants used in guatemala for the treatment of dermatophytic infections. 1. screening for antimycotic activity of 44 plant extracts.skin infections are common diseases in developing countries, of which dermatophytoses are of particular concern in the tropics, especially in infants. through ethnobotanical surveys and literature review 100 plants were detected as being used in guatemala for the treatment of dermatophytoses. of these, 44 plants were screened for in vitro activity against the most common dermatophytes (epidermophyton floccosum, microsporum canis, microsporum gypseum, trichophyton mentagrophytes and trichophyton ...19912056755
novel broad-spectrum metal-based antifungal agents. correlations amongst the structural and biological properties of copper (ii) 2-acetylpyridine n4-dialkylthiosemicarbazones.copper(ii) complexes of the type [cu(l)x], where l = tridentate anion of 2-acetylpyridine n4-diethyl thiosemicarbazone and x = c1 or br, were screened against seven fungal strains pathogenic to man viz. aspergillus niger, aspergillus fumigatus, candida albicans, cryptococcus neoformans, tricophyton rubrum, epidermophyton floccosum and microsporum canis. the greater growth inhibition exhibited by the bromo complex can be explained on the basis of its lower cu(ii)/cu(i) redox couple and greater co ...19911931432
mycologic study of tinea capitis in qatar.the causative dermatophytic species of tinea capitis were identified in 91 patients in qatar. microsporum canis was the most common isolated organism (86.81%) followed by microsporum ferrugineum and trichophyton violaceum. a gray patch type of tinea capitis was the predominant presentation (87.91%), and the disease was more prevalent among qatari boys.19912037406
disinfectants in the control of small animal ringworm due to microsporum canis.twelve disinfectant products or compounds were evaluated for their ability to kill microsporum canis harvested from naturally infected material. the disinfectants were diluted to the concentration recommended for the disinfection of clean surfaces and the potency of each substance was determined by the degree to which it could be further diluted before losing its fungicidal action. hypochlorite, benzalkonium chloride and glutaraldehyde based compounds were the most effective agents and phenolics ...19911957460
[in vitro antifungal activities of amorolfine against fresh isolates from patients with cutaneous mycosis].in vitro antifungal activities of amorolfine (mt-861), a new morpholine antifungal agent, were examined using an agar-dilution method, in comparison with those of 2 other antifungal agents, clotrimazole (ctz) and bifonazole (bfz), against 182 clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, microsporum canis, and epidermophyton floccosum, which had been freshly isolated from a total of 182 cutaneous mycotic patients with various types of dermatophytes or cutaneous candidias ...19911960850
fungal infection as a cause of skin disease in the eastern province of saudi arabia: prevailing fungi and pattern of infection.a total of 4,294 clinically suspected cases of dermatomycoses belonging to 26 different nationalities were examined between april 1984 and april 1988. fungi were demonstrated in routine potassium hydroxide/dimethyl sulfoxide mount in 3,814 cases (88.8%) and the etiology was determined by culture in 2,458 cases (57.2%). tinea versicolor was the predominant fungal infection (30.9% of all infections). onychomycosis and paronychia ranked second in prevalence (16.8%). candidal onychomycosis was the m ...19911803238
tinea corporis due to microsporum canis from an asymptomatic dog.the patient was a 19-year-old female student who purchased a puppy from a pet shop four weeks earlier. at the time of her first examination, an annular edematous erythema with adherent scales and vesicles surrounding its margin was seen on the left forearm. on direct examination of the vesicles, fungal elements were detected, and microsporum canis was isolated. the puppy was a pomeranian and was kept in the house at all times. no clinical lesions were seen on the puppy, and the wood's lamp test ...19911939864
trichophyton rubrum invasion of human hair apparatus in tinea capitis and tinea barbae: light- and electron microscopic study.we have previously reported morphological changes of trichophyton violaceum and microsporum canis in hair apparatuses in tinea capitis. to investigate the morphology of trichophyton rubrum in the human hair apparatus, two cases of tinea capitis and one case of tinea barbae were examined by light- and electron microscopy. the fungal elements, which were located in the lower keratogenous zone, showed non-septate hyphae in the outer part of the hair cortex. with the upward development of the hair l ...19911929541
fungal flora of the haircoat of cats with and without dermatophytosis.in catteries with a long-standing problem of dermatophytosis, microsporum canis was the sole fungal isolate from all cats, regardless of clinical signs. fungal isolates from cats in catteries with an early problem of m. canis infection (less than 30 days) consisted of m. canis mixed with saprophytic fungi, fewer cats with pure m. canis cultures and individual cats that were culture negative for m. canis. when these catteries were resampled at a later date, m. canis was the only fungus isolated f ...19911955948
fungal skin infections associated with animal contact.zoophilic dermatophytes are fungal organisms that primarily infect animals but occasionally infect humans. the most common of these are microsporum canis and trichophyton mentagrophytes. the clinical lesions of zoophilic fungal infections are more inflammatory than those caused by the typical anthropophilic fungi normally transmitted from person to person. to diagnose zoophilic fungal infections, a potassium hydroxide preparation of the skin scrapings may be examined microscopically or a culture ...19912008813
review of dermatophytoses in galicia from 1951 to 1987, and comparison with other areas of spain.we have reviewed all the dermatophytoses diagnosed in galicia during four consecutive 9-year periods 1951-86 and 1987. from 4571 patients, we isolated 3351 fungal strains belonging, in decreasing order of frequency, to the following dermatophyte species: microsporum canis (25.5%), trichophyton rubrum (24.6%), t. mentagrophytes (21.4%), epidermophyton floccosum (11.8%), m. gypseum (5.2%), t. tonsurans (3.9%), t. verrucosum (3.1%), t. schoenlenii (2.5%), t. violaceum (1.2%), t. mengninii (0.3%), m ...19912034261
fungal flora of the coat of pet cats.the fungal flora of the coat of 172 healthy pet cats was examined qualitatively. fungi were isolated from 136 (79%) of the 172 cats. fifteen genera were isolated; 13 are commonly regarded as saprophytes, and 2 (microsporum and trichophyton) are commonly regarded as pathogens. aspergillus, alternaria, penicillium, and cladosporium spp were the most frequently isolated saprophytes. dermatophytic fungi, including microsporum gypseum (n = 1), m vanbreuseghemii (n = 1), and trichophyton rubrum (n = 1 ...19912053732
tinea capitis in the united arab emirates.the authors reviewed the causative agents for tinea capitis in united arab emirates nationals attending tawam hospital, al ain, between 1981 and 1988. microsporum canis was the most prevalent organism isolated. oral griseofulvin remained the treatment of choice. the addition of isotretinoin appeared promising in the chronic inflammatory forms.19912001903
a survey of dermatophytes from human patients in the united states from 1985 to 1987.a survey of dermatophytes isolated from patients seeking medical advice was made from 1985 to 1987 in the united states. the survey included 54 locations with data from 45 cities and one state. listing of the isolated dermatophytes and the frequency given by percentage of the total follows: trichophyton rubrum 54.8%, t. tonsurans 31.3%, t. mentagrophytes 6.0%, microsporum canis 4.0%, epidermophyton floccosum 2.0%, m. gypseum 0.6%, and t. verrucosum 0.2%. out of a total of 14,696 isolates m. audo ...19911875984
[outbreak of dermatophytosis caused by microsporum canis in a closed community in the province of soria]. 19911932251
prevalence of superficial mycoses in the aosta valley region of italy from 1984 to 1989.this report represents the results of the culture tests for fungi carried out in the aosta valley region of italy from 1984 to 1989. the pathological material consisted of cutaneous scales, hair and nails. it was possible to identify 91.8% of the isolates: out of these, 36.1% were dermatophytes, 21% were aspergillus spp, 15.6% deuteromycetes, 15% yeasts and 4.1% members of the family mucoraceae. the resulting data indicate that microsporum canis was the most wide-spread species (73.7%) among the ...19911795730
synthesis and antimicrobial activities of some new tetrahydro-2h-1,3,5-thiadiazine-2-thione derivatives of ampicillin.compounds having alpha-[dihydro-5-substituted 6-thioxo-2h- 1,3,5-thiadiazine-3(4h)-yl]benzylpenicillin structure were synthesized by the reaction of ampicillin trihydrate, formaldehyde and dithiocarbamic acid salts. the structures were evident from chemical and spectral analysis. the antimicrobial activities of the compounds were investigated against some gram-positive (staphylococcus aureus and streptococcus faecalis) and gram-negative (escherichia coli and pseudomonas aeruginosa) bacteria and ...19902288482
[dermatophyte infections caused by microsporum canis and microsporum audouinii in the greifswald area].report of serial diseases of dermatophytoses caused by m. canis (5 patients) and m. audouinii (9 patients). two cats and a dog were the infective source of m. canis-infection. m. audouinii-infection was stated in a children ward; here the infective source had not been detected. remarkable are the identical morphological lesions of tinea capitis resp. corporis and the affections of adults in the two groups of patients. griseofulvin therapy and additional veterinary hygienical treatment in case of ...19902365106
the value of electrophoretic protein patterns for the study of microsporum canis.whole-cell protein analysis of clinical isolates of microsporum canis by polyacrylamide gel electrophoresis (page) showed small but inconsistent differences in protein patterns. all clinical isolates closely resembled the (-) mating type of arthroderma otae. a reference strain of a. otae (+) mating type from japan gave a page pattern which was distinct from those of the clinical isolates. mating studies showed that the progeny of these reference (+) and (-) mating types had a variety of distinct ...19902380880
effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs.butenafine hydrochloride, n-4-tert-butylbenzyl-n-methyl-1-naphthalenemethylamine hydrochloride (butenafine), is a novel antifungal agent of the class of benzylamine derivatives. butenafine was investigated for its activity against guinea pig dermatophytosis caused by trichophyton mentagrophytes or microsporum canis in comparison with those of naftifine, tolnaftate, clotrimazole, and bifonazole. topical butenafine showed excellent efficacy against dermatophytosis when it was applied once daily, a ...19902073116
[clinico-epidemiological findings in tinea capitis in adults].clinical and epidemiological data on 15 subjects with tinea capitis are reported. the patients, aged between 19 and 74, were observed from 1.1.1980 to 30.6.1990; 14 of them were females. the evidence of different clinical pictures is stressed. microsporum canis was isolated in 7 cases, trichophyton violaceum in 6 cases, and trichophyton schoenleinii in 2 cases.19902089001
cycloheximide enhances factor binding to the native 40s ribosomal subunit of microsporum canis.native and derived ribosomal particles from the mycelial cells of microsporum canis grown in the presence and absence of cycloheximide were compared by cscl equilibrium density gradient centrifugation. since the buoyant densities of ribonucleoprotein complexes are dependent on the protein-rna ratio, they reflect the composition of these particles. the native monosomes from cells grown in the presence and absence of cycloheximide had a buoyant density of 1.585 g/cc. the native 60s subunits showed ...19902099146
in vitro nail invasion by pathogenic and non-pathogenic fungi under different culture conditions.data from the literature suggest that the nutritional environment can modify major metabolic functions of fungi and possibly their aggressivity towards keratinous structures. trichophyton rubrum (tr), microsporum canis (mc), scopulariopsis brevicaulis (sb), aspergillus fumigatus (af) and penicillium spec. (p) were inoculated on media of different nutritional value, in presence of nail fragments. the activity of the fungi was evaluated at two and four weeks for intensity and depth of invasion of ...19902103593
wool-colonizing micro-organisms capable of utilizing wool-lipids and fatty acids as sole sources of carbon and energy.two keratinolytic fungi, chrysosporium keratinophilum and malbranchea anamorph of uncinocarpus reesii, and another three wool-colonizing fungi not previously reported to be keratinolytic, aspergillus fumigatus, a. flavus and scopulariopsis candida, were isolated from soil samples baited with animal wool. these fungi were tested for their ability to utilize wool-lipids as sole source of carbon and energy. the lipid contents of wool of various animals ranged between 2 and 5%. the different lipid e ...19902126788
dermatophytoses as occupational dermatoses in industrialized countries. report on two cases from munich.although interest in dermatophytoses as occupational dermatoses nowadays focuses on developing countries, pertinent cases are still also seen in industrialized countries. two recent cases from munich are reported in which trichophyton verrucosum had been acquired by a cattle farmer and microsporum canis by a veterinary surgeon from a pet cat.19902141106
proton magnetic resonance study of cycloheximide-ribosome interactions.cycloheximide-ribosome interactions from sensitive and resistant organisms were studied by proton magnetic resonance spectroscopic techniques. the two methyl resonances of cycloheximide upon interaction with ribosomes from saccharomyces cerevisiae showed preferential broadening. comparison of cycloheximide line broadening as effected by ribosomes from s. cerevisiae (sensitive) and microsporum canis (resistant) revealed that less cycloheximide is bound to the m. canis ribosomes. from the decrease ...19902206134
[microsporum infection in patients treated at the dermatological clinic, medical academy, in gdańsk 1984-1988].in the years 1984-1988 in the department of dermatology, m. a. in gdańsk 80 cases of microsporum mycoses were diagnosed. the cases were due to microsporum canis. among 80 cases of this mycosis we found 59 children aged from 2 to 15 years and 21 subjects aged over 15 years. in children the most cases were diagnosed in the age group 4-7 years. in 40 cases (50%). m. canis produced lesions of hairless skin and in 36 cases (45%) the scalp was involved.19902217836
detection of keratinolytic proteinase in skin tissues from guinea pigs infected with microsporum canis by an immunoperoxidase technique.an immunoperoxidase technique was performed to detect keratinolytic proteinase (kpase) in sections of the skin taken from guinea pigs infected with microsporum canis and in cultured m. canis using polyclonal antisera to purified kpase. of tissue samples from guinea pigs infected with m. canis, all sections of erythematous lesions showed positive staining mainly in the horny layer and the hair follicles. positive depositions were seen only at the level of the outer and inner root sheaths of the h ...19902288900
tinea capitis in the netherlands (rotterdam area).this retrospective study reviews the occurrence and treatment of various forms of tinea capitis at the out-patient clinic for dermatology and pediatric dermatology of the university hospital sophia/dijkzigt over the period 1977-1988. tinea capitis was diagnosed in 64 children. trichophyton violaceum was the pathogen most frequently isolated, with microsporum canis ranking second. the potassium hydroxide preparation was positive in 58% of the cases. four cases showed a positive potassium hydroxid ...19902342520
dermatophytes in healthy chilians.to study the presence of dermatophytes in healthy persons, 1060 skin samples from the scalp, complexion, inguinal region and sole were taken from 265 healthy individuals who live in valdivia, chile. the carpet technique of mariat and tapia was used. the isolated dermatophytes were identified according to rebell and taplin. zoophilic dermatophytes were isolated in only 4.9% of the healthy individuals. microsporum canis was found in the scalp and inguinal area of children (1.5%). trichophyton ment ...19902352545
in vitro susceptibility of dermatophytes from munich to griseofulvin, miconazole and ketoconazole.various recent clinical isolates of trichophyton rubrum, trichophyton mentagrophytes, microsporum canis and epidermophyton floccosum from munich were subjected to antimicrobial susceptibility testing using the microdilution method. both azoles miconazole and ketoconazole were found to be more active than griseofulvin. comparatively high inhibitory concentrations of griseofulvin were especially found with tr. mentagrophytes. on the whole miconazole turned out to be even somewhat more effective th ...19902359418
[dermatophytosis in a urban setting: prospective study of 135 cases].during a period of one year all patients referred to the dermatology department with the diagnosis of dermatophytosis were studied to determine the incidence. etiology, and epidemiology of these infections in the northeast of madrid. we have evaluated the sensitivity and specificity of the direct examination with 10% koh with respect to the culture as well as the correlation between the clinical diagnosis and the result of the mycologic examination. the annual incidence was 8.4 cases per 10,000 ...19902152479
itraconazole in the treatment of tinea capitis.fifty patients with tinea capitis were treated with itraconazole, 25 to 100 mg/day, for 20 to 73 days in six countries. forty-seven patients (94%) responded clinically (healed or markedly improved) to therapy, of which 38 patients (76%) completely healed and 9 patients (18%) markedly improved. three patients (6%) failed therapy. forty-two patients were assessable for mycologic examination; 38 patients (93%) converted mycologically to negative and 4 patients (7%) remained positive for organisms. ...19902170474
[urban cycles of zoonotic mycoses].based on their own results assembled during mycological examinations of 9958 subjects, 5496 animals and 648 specimens of non-animal substrates, and using data from the literature, the authors tried to formulate general laws concerning the prevalence of causal agents of mycoses with a zoonotic character which circulate steadily in urban areas: microsporum canis, m. persicolor, trichophyton mentagrophytes, m. equinum and t. equinum, t. verrucosum, some geophilic dermatophytes, cryptococcus neoform ...19902150623
[the dynamics of dermatomycetes in the bashkir assr in 1979-1987].analysis of changes in dermatomycetes incidence in bashkiria in 1979-1987 has shown the predominance of zoophilic fungi in the latest 9 years, while the share of anthroponotic fungi has made up but 8.6%. the major agent of dermatophytosis in the republic was microsporum canis. the incidence of trichophyton verrucosum and trichophyton mentagrophytes v. gypzeune has grown of late, this necessitating the detection of new epidemiologic factors, contributing to dissemination of these mycoses and the ...19902343671
additive effect of the combination of griseofulvin and ketoconazole against microsporum canis in vitro.the susceptibility of 28 strains of microsporum canis to griseofulvin, to ketoconazole and to a combination of both antifungal drugs was determined. griseofulvin proved to be more active than ketoconazole. the combination of both antifungal agents was found to exert an additive effect.19892608097
[evaluation of the efficacy of a new antimycotic molecule for topical use: naftifine].the antifungal efficacy and tolerability of naftifine (cream, gel, 1% solution), were tested in an open, mycologically controlled study in 29 patients (mean age 32.7 +/- 2.8 years; 15 males, 14 females) with dermatomycosis caused by dermatophytes and yeasts. particularly, 16 patients were affected with tinea corporis; 11 patients by pityriasis versicolor and 2 other by cutaneous candidiasis. the mean treatment period was 32.9 days in a range from 1 to 44 days. only one patient, with cutaneous ca ...19892620916
Displaying items 901 - 1000 of 1282